#49297

Date: September 22, 2021

Subject: Intuitive Surgical, Inc. - 3 For 1 Stock SplitOption Symbol: ISRGEx-Date: 10/5/21

Intuitive Surgical, Inc. (ISRG) has announced a 3 for 1 stock split. The Ex-distribution Date is October 5, 2021. The Payable Date is October 4, 2021. The Record Date is September 27, 2021.

Pursuant to Article VI, Section 11A, of OCC's By-Laws, all Intuitive Surgical, Inc. options will be adjusted as follows:

Contract Adjustment

Effective Date: October 5, 2021

Option Symbol: ISRG remains ISRG

New Multiplier: 100 (e.g., for premium or strike dollar extensions 1.00 will equal $100)

Contract Multiplier: 3.00

Strike Divisor: 3.00

New Deliverable Per Contract: 100 Intuitive Surgical, Inc. (ISRG) Common Shares

CUSIP: 46120E602

Old Strike New Strike195.00 65.00200.00 66.67210.00 70.00220.00 73.33230.00 76.67240.00 80.00250.00 83.33260.00 86.67270.00 90.00280.00 93.33290.00 96.67

300.00 100.00310.00 103.33320.00 106.67330.00 110.00340.00 113.33350.00 116.67360.00 120.00370.00 123.33380.00 126.67390.00 130.00400.00 133.33410.00 136.67420.00 140.00430.00 143.33440.00 146.67450.00 150.00460.00 153.33470.00 156.67480.00 160.00485.00 161.67490.00 163.33495.00 165.00500.00 166.67505.00 168.33510.00 170.00515.00 171.67520.00 173.33525.00 175.00530.00 176.67535.00 178.33540.00 180.00545.00 181.67550.00 183.33555.00 185.00560.00 186.67565.00 188.33570.00 190.00575.00 191.67580.00 193.33585.00 195.00590.00 196.67595.00 198.33600.00 200.00605.00 201.67610.00 203.33615.00 205.00620.00 206.67625.00 208.33630.00 210.00635.00 211.67

640.00 213.33645.00 215.00650.00 216.67655.00 218.33660.00 220.00665.00 221.67670.00 223.33675.00 225.00680.00 226.67685.00 228.33690.00 230.00695.00 231.67700.00 233.33705.00 235.00710.00 236.67715.00 238.33720.00 240.00725.00 241.67730.00 243.33735.00 245.00740.00 246.67745.00 248.33750.00 250.00755.00 251.67760.00 253.33765.00 255.00770.00 256.67775.00 258.33780.00 260.00785.00 261.67790.00 263.33795.00 265.00800.00 266.67805.00 268.33810.00 270.00815.00 271.67820.00 273.33825.00 275.00830.00 276.67835.00 278.33840.00 280.00845.00 281.67850.00 283.33855.00 285.00860.00 286.67865.00 288.33870.00 290.00875.00 291.67880.00 293.33885.00 295.00

890.00 296.67895.00 298.33900.00 300.00905.00 301.67910.00 303.33915.00 305.00920.00 306.67925.00 308.33930.00 310.00935.00 311.67940.00 313.33945.00 315.00950.00 316.67955.00 318.33960.00 320.00965.00 321.67970.00 323.33975.00 325.00980.00 326.67985.00 328.33990.00 330.00995.00 331.67

1,000.00 333.331,005.00 335.001,010.00 336.671,015.00 338.331,020.00 340.001,025.00 341.671,030.00 343.331,035.00 345.001,040.00 346.671,045.00 348.331,050.00 350.001,055.00 351.671,060.00 353.331,065.00 355.001,070.00 356.671,075.00 358.331,080.00 360.001,085.00 361.671,090.00 363.331,095.00 365.001,100.00 366.671,105.00 368.331,110.00 370.001,115.00 371.671,120.00 373.331,125.00 375.001,130.00 376.671,135.00 378.33

1,140.00 380.001,145.00 381.671,150.00 383.331,155.00 385.001,160.00 386.671,165.00 388.331,170.00 390.001,175.00 391.671,180.00 393.331,185.00 395.001,190.00 396.671,195.00 398.331,200.00 400.001,210.00 403.331,220.00 406.671,230.00 410.001,240.00 413.331,250.00 416.671,260.00 420.001,270.00 423.331,280.00 426.671,290.00 430.001,300.00 433.331,310.00 436.671,320.00 440.001,330.00 443.331,340.00 446.671,350.00 450.001,360.00 453.331,370.00 456.671,380.00 460.001,390.00 463.331,400.00 466.671,410.00 470.001,420.00 473.331,430.00 476.671,440.00 480.001,450.00 483.331,460.00 486.671,470.00 490.001,480.00 493.331,490.00 496.671,500.00 500.001,510.00 503.331,520.00 506.671,530.00 510.001,540.00 513.331,550.00 516.671,560.00 520.001,570.00 523.33

1,580.00 526.671,590.00 530.001,600.00 533.331,610.00 536.671,620.00 540.00

These strikes reflect strikes that are active as of the publication date of this information memo and will be adjusted on the ex-date. Any strikes added after the publication of this memo and prior to the ex-date will be adjusted using the strike divisor stated above.

Disclaimer This Information Memo provides an unofficial summary of the terms of corporate events affecting listed options or futures prepared for the convenience of market participants. OCC accepts no responsibility for the accuracy or completeness of the summary, particularly for information which may be relevant to investment decisions. Option or futures investors should independently ascertain and evaluate all information concerning this corporate event(s).

The determination to adjust options and the nature of any adjustment is made by OCC pursuant to OCC By-Laws, Article VI, Sections 11 and 11A. The determination to adjust futures and the nature of any adjustment is made by OCC pursuant to OCC By-Laws, Article XII, Sections 3, 4, or 4A, as applicable. For both options and futures, each adjustment decision is made on a case by case basis. Adjustment decisions are based on information available at the time and are subject to change as additional information becomes available or if there are material changes to the terms of the corporate event(s) occasioning the adjustment.

ALL CLEARING MEMBERS ARE REQUESTED TO IMMEDIATELY ADVISE ALL BRANCH OFFICES AND CORRESPONDENTS ON THE ABOVE. For questions regarding this memo, call Investor Services at 1-888-678-4667 or email investorservices@theocc.com. Clearing Members may contact Member Services at 1-800-544-6091 or, within Canada, at 1-800-424-7320, or email memberservices@theocc.com.