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Intramuscular Anabolic Steroid Injection Leading to Life-Threatening Clostridial Myonecrosis by Matthew D. Driscoll, Anisha Arora, and Michael L. Brennan J Bone Joint Surg Am Volume 93(16):e92 August 17, 2011 ©2011 by The Journal of Bone and Joint Surgery, Inc.

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During the initial nine hours of hospitalization, the serum hemoglobin level dropped dramatically as a result of toxin-mediated hemolytic anemia, while serum creatinine and lactic acid levels increased. Matthew D. Driscoll et al. J Bone Joint Surg Am 2011;93:e92 ©2011 by The Journal of Bone and Joint Surgery, Inc.

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Page 1: Intramuscular Anabolic Steroid Injection Leading to Life- Threatening Clostridial Myonecrosis by Matthew D. Driscoll, Anisha Arora, and Michael L. Brennan

Intramuscular Anabolic Steroid Injection Leading to Life-Threatening Clostridial Myonecrosis

by Matthew D. Driscoll, Anisha Arora, and Michael L. Brennan

J Bone Joint Surg AmVolume 93(16):e92

August 17, 2011

©2011 by The Journal of Bone and Joint Surgery, Inc.

Page 2: Intramuscular Anabolic Steroid Injection Leading to Life- Threatening Clostridial Myonecrosis by Matthew D. Driscoll, Anisha Arora, and Michael L. Brennan

CT scout film and axial images demonstrate diffuse air within the right vastus lateralis muscle and in the fascial planes from the pelvis to the knee.

Matthew D. Driscoll et al. J Bone Joint Surg Am 2011;93:e92

©2011 by The Journal of Bone and Joint Surgery, Inc.

Page 3: Intramuscular Anabolic Steroid Injection Leading to Life- Threatening Clostridial Myonecrosis by Matthew D. Driscoll, Anisha Arora, and Michael L. Brennan

During the initial nine hours of hospitalization, the serum hemoglobin level dropped dramatically as a result of toxin-mediated hemolytic anemia, while serum creatinine and lactic acid levels

increased.

Matthew D. Driscoll et al. J Bone Joint Surg Am 2011;93:e92

©2011 by The Journal of Bone and Joint Surgery, Inc.

Page 4: Intramuscular Anabolic Steroid Injection Leading to Life- Threatening Clostridial Myonecrosis by Matthew D. Driscoll, Anisha Arora, and Michael L. Brennan

Meat broth was injected with contents from the patient's steroid vial (center).

Matthew D. Driscoll et al. J Bone Joint Surg Am 2011;93:e92

©2011 by The Journal of Bone and Joint Surgery, Inc.