international science & engineering visualization … · 2010-03-05 · netic analyzers take...

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Visualization in all its forms has the power to illuminate and educate. It explains and makes clear all aspects of the world around us. It feeds insight and provokes curiosity. The National Science Foundation (NSF) and the journal Science, published by the American Association for the Advancement of Science, invite you to participate in this year’s Challenge. The competition recognizes scientists, engineers, visualization specialists, and artists who produce innovative work in visual communication. Winning entries will be published in Science and Science Online, and will be displayed on the NSF web site. Award Categories Photographs/Pictures Illustrations/Drawings Informational Posters and Graphics Interactive Games Non-Interactive Media INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION CHALLENGE CALL FOR ENTRIES ENTRY DEADLINE: SEPTEMBER 15, 2010 C E I: ..//

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Page 1: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

Visualization in all its

forms has the power to

illuminate and educate. It

explains and makes clear

all aspects of the world

around us. It feeds insight

and provokes curiosity.

The National Science

Foundation (NSF) and the

journal Science, published by the

American Association for the

Advancement of Science, invite

you to participate in this year’s

Challenge. The competition

recognizes scientists, engineers,

visualization specialists, and

artists who produce innovative

work in visual communication.

Winning entries will be

published in Science and Science

Online, and will be displayed on

the NSF web site.

Award Categories

• Photographs/Pic tures

• I l lustrat ions/Drawings

• Informational Posters

and Graphics

• Interac tive Games

• Non- Interac tive Media

I N T E R N A T I O N A L S C I E N C E & E N G I N E E R I N G

V I S U A L I Z A T I O N C H A L L E N G E

CALL FOR ENTRIES

ENTRY DEADLINE: SEPTEMBER 15, 2010

C E I:

..//

Page 2: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

“How dowe know

this leadmolecule

is novel?”

Need to assess the novelty of substances?

SciFinder is the answer.

It includes CAS REGISTRY,SM themost comprehensive

substance information available, integrated with relevant

journal articles and patents.

Give your research team the highest quality andmost timely

scienti�c information resource.

Make SciFinder an essential part of your research process.

For more information about SciFinder, visit www.cas.org or

e-mail [email protected].

SciFinder®—Part of the process.TM

CAS is a division of the American Chemical Society

��

SciFinder—

of course.

www.cas.org

Page 3: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

Visit www.emdbiosciences.com/widescreen for technical information on the broad

range of WideScreen™ products available. To order WideScreen™ products: USA and

Canada 800.854.3417. Outside North America contact your local Merck office.

Refer to next page for details.

Without high-quality biomarker data,

am I making the best decisions?

What is your risk tolerance?

WideScreen™ BeadPlex™ Multiplex Assays.

Assay solutions that are extensively

validated for clarity you can count on.

When it comes to biomarker patterns,

insight is everything.

That's what's in it for you. EMD Chemicals

Page 4: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

Cancer:Human Cancer Panel 1 (Tumor Markers)•

Human Cancer Panel 2 (Growth Factors)•

Human Breast Cancer Panels (3)•

Human MMP Panel•

Signaling Cancer Panels:Erk/MAPK Pathway Panels 1&2•

Receptor Tyrosine Kinase (RTK) Panel 1•

Phospho-Receptor Tyrosine•

Kinase (RTK) Panel 1

Phospho-EGFR Profiling 9-plex•

Coming soon:Receptor Tyrosine Kinase (RTK) Panel 2•

Phospho-Receptor Tyrosine•

Kinase (RTK) Panel 2

CardioVascular Disease:Human CVD Panel 1 (Apolipoprotein)•

Human CVD Panel 2 (Inflammation)•

Human CVD Panel 3•

Human CVD Panel 4•

Human CVD Panel 5 (Acute Phase)•

Human CVD Panel 6•

Metabolism:Human Metabolism Panel 1•

Human Metabolism Panel 2•

Human Hormone Panel 1•

Rat Metabolism Panel 1•

WideScreen™ BeadPlex™ Biomarker Assay Kits

Large portfolio of multiplex assays developed both internally atMerck KGaA, and with Rules Based Medicine (RBM)Created using assays from RBM’s HumanMAP® and Rat KidneyMAP® service portfolioFocused on specific therapeutic areas and disease statesOur continually expanding portfolio includes:

WideScreen™ BeadPlex™ Toxicity AssaysPanels of key toxicity biomarkers used to detect kidney impairment due to drug-induced toxicity. In

2008, the Predicitive Safety Testing Consortium (PSTC), a public-private consortium led by the Critical

Path Institute, submitted a list of urinary biomarkers indicative of drug-induced kidney damage to

the FDA and EMEA regulatory authorities. The FDA and EMEA have issued new guidelines on the

submission of the biomarkers as indicators of kidney damage in pre-clinical studies. EMD, in partnership

with RBM, has now released assay kits that include four of the seven newly accepted biomarkers

(KIM-1, ß2M, Cystatin C, and Clusterin) along with six other key protein markers for kidney injury.

Rat Kidney Toxicity Panel 1 (KIM-1, ß2-microglobulin, GST• α, TIMP-1, VEGF)

Rat Kidney Toxicity Panel 2 (Cystatin C, NGAL, Calbindin, Clusterin, Osteopontin)•

WideScreen™ BeadPlex™ Multiplex Assays

for the Luminex® xMAP® Platform

WideScreen™ Biomarker Analysis for:

WideScreen™BeadPlex™Multiplex Assaysfor the xMAP®Technology Platform

Toxicity•

Cancer•

Cardiovascular Disease (CVD)•

Metabolism•

Inflammation•

Hormones•

Signaling Pathways•

©Copyright 2009 EMD Chemicals, an affiliate of Merck KGaA, Darmstadt, Germany. All rights reserved. Each product is intended to be used

for research purposes only. It is not to be used for drug or diagnostic purposes nor is it intended for human use. Novagen® is a registered

trademark of EMD Chemicals Inc. in the United States, Europe, Japan and Australia. WideScreen™ and BeadPlex™ are trademarks of EMD

Chemicals Inc. Luminex®, xMAP®, and the xMAP® medallion are registered trademarks of Luminex Corporation. WideScreen™ Biomarker

Assays are manufactured by Rules Based Medicine. RodentMAP™, HumanMAP™ and KidneyMAP™ are trademarks of Rules Based Medicine.

©Copyright 2009 EMD Chemicals, an affiliate of Merck KGaA, Darmstadt, Germany. All rights reserved. Each product is intended to be used

for research purposes only. It is not to be used for drug or diagnostic purposes nor is it intended for human use. Novagen® is a registered

trademark of EMD Chemicals Inc. in the United States, Europe, Japan and Australia. WideScreen™ and BeadPlex™ are trademarks of EMD

Chemicals Inc. Luminex®, xMAP®, and the xMAP® medallion are registered trademarks of Luminex Corporation. WideScreen™ Biomarker

Assays are manufactured by Rules Based Medicine. RodentMAP™, HumanMAP™ and KidneyMAP™ are trademarks of Rules Based Medicine.

Visit www.emdbiosciences.com/widescreenfor technical information on the broad

range of WideScreen™ products available.

To order WideScreen™ products: USA

and Canada 800.854.3417. Outside North

America contact your local Merck office.

Page 5: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

GE HealthcareLife Sciences

It’s all the convenience you want in a spectrophotometer, packaged in a portable,

ergonomic device. NanoVue Plus features a new hydrophobic, gold-colored sample

plate coating that delivers outstanding results for sub-microliter amounts of proteins

and nucleic acids. It operates without a PC and does not require time-consuming third-

party path length recalibration.

NanoVue Plus enables easy protocol selection using advanced software that includes

intuitive drop-down lists for the full range of CyDye™ fluorescent dyes, as well as lists

for common fluors. Results can exported using a USB cable or Bluetooth™ connections

for print via computer (PVC) or stored using the new SD card option. An integrated

printer is also available.

• Swift, accurate analysis of 0.5 µl samples

of nucleic acids and proteins

• Practical drop and measure mechanism

• Outstanding sample recovery

• Reliable and reproducible measurements

• Automatic self-calibration on start up

• Path length recalibration kit available

as accessory

Experience the NanoVue Plus first hand.

Register for a trial at:

www.gelifesciences.com/tryNanoVuePlus

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Drop. Measure. Done.NanoVue™ Plus: intelligent performanceacross all spectrophotometer applications

I ÄKTA I Amersham I Biacore I IN Cell Analysis I Whatman I GE Service I

Page 6: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

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Use QIAGEN® solutions from sample to result,and benefit from sensitive and reliable detection systems:

■ Quantitative, real-time PCR detection

■ Automated analysis of DNA fragments and RNA

■ Pyrosequencing® sequence-based DNA detection and quantification

■ Optimized, ready-to-use assays and reagents

Making improvements in life possible — www.qiagen.com

Detection platforms, assays,

and analysis software

by QIAGEN

Choose QIAGEN for detection

Sample & Assay Technologies

Page 7: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

www.abcam.com

We do proteins too!Over 8,000 proteins and peptides available, with 150 new products added

every month. All supported by industry leading datasheets providing detailed

application and technical data, just one click away!

Stay up-to-date on the latest developments with our human expressed proteins

• Optimal post-translational modifications

• Biological activity

• Fc chimera proteins offering advantages in dimerization

Visit www.abcam.com/proteins for more information

Abcam Inc.1 Kendall Square, Ste 341

Cambridge, MA 02139-1517

USA

Tel: 1-617-225-2272

Toll free: 1-888-77-ABCAM

Toll free Fax: 1-866-739-9884

Bioactivity of human expressed proteins

Assays were conducted to compare the

bioactivity of human expressed proteins

and their non-human expressed

counterparts such as E.coli expressed or

other mammalian expressed proteins.

Page 8: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

CLONING & MAPPINGDNA AMPLIFICATION

& PCRRNA ANALYSIS

PROTEIN EXPRESSION &

ANALYSIS

GENE EXPRESSION

& CELLULAR ANALYSIS

Reagents for Sample Preparation from New England Biolabs

Introducing NEBNext™, a series of highly pure reagents that facilitate sample preparation for downstream applications such

as next generation sequencing and expression library construction. Available in sets, master mixes and modules, these robust

reagents undergo stringent quality controls and functional validation, ensuring maximum yield, convenience and value.

www.neb.com

STUNNING QUALITY

Sequencing coverage map of the E. coli genome after using

NEBNext™ DNA Sample Prep Reagent Set 1 for Sample Preparation

E. coli strain MG1655 gDNA was prepared with NEBNext DNA Sample Prep Reagent Set I and sequenced on an Illumina

Genome Analyzer II.

Now available:NEBNext™ dsDNA Fragmentase™

an enzyme-based solution for the

fragmentation of DNA

For more information about NEBNext, including customized solutions,please contact [email protected].

160

140

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100

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Genome Position

Page 9: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

Today millions of people with Alzheimer’s can no longer remember the onesthey love. That number is expected to increase dramatically over the next 20years. And it’s one more reason MetLife Foundation continues to supportresearch to find a cure. This year the Foundation honors the outstanding workof Todd E. Golde, MD, PhD, University of Florida, Gainesville, Edward H. Koo, MD,University of California, San Diego, Eckhard Mandelkow, PhD, and Eva-MariaMandelkow, MD, PhD, Max-Planck-Institute for Structural Molecular Biology,Hamburg, Germany, with the MetLife Foundation Award for Medical Research.

Imagine not being able to recognize your best friend.

©2010 MetLife Foundation, NY, NY. PEANUTS ©UFS, Inc.

Page 10: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

The smarter the mouse

the quicker the drug gets to market.

From disease models that facilitate target identification, to humanized models

that test the safety and efficacy of potential therapeutics, Taconic’s “smart” mice

play a pivotal role in speeding new drugs to market.

Taconic’s rapidly expanding portfolio of fully licensed, off-the-shelf ADME-Tox

transgenic models, as well as transgenic models for short term carcinogenicity

testing provide valuable insights into how your drug will behave in humans.

Taconic introduces another breakthrough in in vivo compound testing with

its new transADMET program. Developed in conjunction with CXR Biosciences,

transADMET is transforming the discovery process by better predicting ADMET

in humans. New humanized models are available now.

To learn how Taconic’s “smart mice” can accelerate your

research and help speed a drug to market, visit our website,

www.taconic.com/SOT

Page 11: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

New Products, Services, and Solutions

SCIENCE

LA

B S

OLU

TIO

NS

To View

Sign Up At :

www.sciencemag.org/webinar

Webinar sponsored by Cyntellect

Brought to you by the

AAAS/Science Business Office

The Need for Standardization

Moving Stem Cell

Research Forward

Webinar

Participating Experts:

Ron McKay, Ph.D.National Institutesof HealthBethesda, MD

Mark D. Noble, Ph.D.University of RochesterMedical CenterRochester, NY

AmyWagers, Ph.D.Harvard UniversityBoston, MA

Recorded Live!

On January 28, 2010

Webinar viewers will:

• learn about common hurdles to beovercome when culturing stem cells

• obtain guidance on best practices forhandling and manipulating stem cells

• hear about the latest technologiesfor standardizing and automatingstem cell culture

www.AccuriCytometers.com

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The C6 uses de-ionized water as sheath, reducing everydaycosts to just a few cents.

Build new scientific relationships andexplore the best way to conduct a clinicaland translational science career at CTSciNet,the new online community from Science,Science Careers, and AAAS made possibleby the Burroughs Wellcome Fund.

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Page 12: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

It becomes you.

Introducing the 3500 Series Genetic Analyzer.

Get ready to make an amazing discovery: the new 8-capillary and 24-capillary 3500 Series Ge-

netic Analyzers take DNA analysis to an entirely new level of performance. A level where your

daily workflow seems like a natural extension of your own intuition. Where precise, quality-

assured data inspires greater confidence. And where a new consumables design

and intuitive software interface keep you current and in control.

Take a closer look, and you’ll find the new 3500 and 3500xL Genetic Analyzers are like

second nature. Which is our first priority when it’s your data.

Discover the 3500 System at www.appliedbiosystems.com/3500Series

FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.

© 2010 Life Technologies Corporation. All rights reserved. The trademarks mentioned herein are the property of Life Technologies Corporation or their respective owners.

For those who require IVD-marked devices, the 3500 Dx and the 3500xL Dx Genetic Analyzers and system accessories meet the requirements of the In Vitro Diagnostics Medical Devices Directive (98/79/EC). The 3500 Dx and 3500xL Dx systems are for distribution and use in

specific European countries only. For more information about the 3500 Dx Series Systems, contact your Applied Biosystems representative.

Easy-to-Use

Consumables

Control at

Your Fingertips

Quality-Assured

Data

Page 13: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

ADVANCES IN SCIENCE AND MEDICINE ARE CHANGING THE FACE OF PULMONARY, CRITICAL

CARE AND SLEEP. STAY AT THE FOREFRONT OF YOUR PROFESSION BY ATTENDING

THE AMERICAN THORACIC SOCIETY’S 2010 INTERNATIONAL CONFERENCE.

ATS 2010•New OrleansLouisiana MAY 14-19

• Epigenomics in Lung Cancer: Linking Development to Disease

• Lipid Mediators in Pathogenesis and Resolution of Acute Lung Injury

• Host Defense Mechanisms in Pulmonary Infection*

• Pushing Stem Cells: Cellular Plasticity

• Quantitative Assessment of Lung Structure: Principles and Practical Applications*

• Scientific Breakthroughs of the Year: Stem Cells and Regenerative Medicine

• Coins for the Boatman: Clearance of Apoptotic Cells in Lung Disease

• Vascular-Matrix Interactions in Lung Development and Disease

• Cells in Lung Injury and Repair of the Lung: Scientific and Translational Importance

• Top-Notch Decisions in Lung Development and Disease

*Postgraduate course

Scientists from nearly 100 countries are expected to participate in the 2010ATS International Conference.With more than 400 sessions, 800 speakers and 5,000 original research abstracts, attendees cansample a broad spectrum of topics or concentrate on the latest findings in respiratory molecular and cellbiology, lung structure and function, inflammatory biology and gene therapy.

Here is a selection of scientific and clinical sessions:

Registration for the 2010ATS

International Conference is now open.

Learn more about these and other sessions in

the 2010Advance Program, which is available

online at

www.thoracic.org/go/international-conference

MEETS

THE

WHERE THE BASIC SCIENCE

OF MEDICINE

OCTOBER 2009 | Vol. 1 | Nos. 1–4

Submit your work to Science

Translational Medicine today!

INTEGRATING MEDICINE AND SCIENCE

In 2009, AAAS and Science launched Science TranslationalMedicine, a new journal focused on applications of basicresearch knowledge that will improve human health.

The journal’s goal is simple: to help the scientificcommunity harness decades of progress in research atthe basic level and translate these biological discoveriesintomedical advances. Take this opportunity to have yourwork recognized in this groundbreaking new journal.

Papers in the following areas will be reviewed andconsidered for publication:

• Animal &Human Studies• Applied Physical Sciences• Behavior• Bioengineering• Biomarkers• Cancer• Cardiovascular Disease• Cell Culture• Chemical Genomics/Drug Discovery

• DataMining• Drug Delivery• Gene Therapy/RegenerativeMedicine

• Imaging

• Immunology/Vaccines• Infectious Diseases• Medical Informatics• Medical Nanotechnology• Metabolism/Diabetes/Obesity

• Neuroscience/Neurology/Psychiatry

• Pharmacogenetics• Policy• Toxicology andPharmacokinetics

• And other interdisciplinaryapproaches tomedicine

www.ScienceTranslationalMedicine.org

Page 14: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

1149www.sciencemag.org/products SCIENCE VOL 327 26 FEBRUARY 2010

NEW PRODUCTS

LIFE SCIENCE TECHNOLOGIES

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are

featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or

materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

AAAS/Science Business Office

FLOW CYTOMETERSThe guava easyCyte 8HT flow cytometry system is a compact, af-

fordable, six-color detection system with 96-well automation that al-

lows scientists to move their research out of the core lab and into

their own lab. The system enables researchers to carry out highly

multiplexed experiments in which six targets and eight parameters

can be simultaneously analyzed in a single sample of cells. In addi-

tion to allowing researchers to analyze more targets, the six-color

detection range also provides greater freedom to choose fluores-

cent dyes with well-separated emission spectra, which reduces the

chance of overlap in the resulting signals and improves data quality.

Millipore

For information 978-715-1567 www.millipore.com

COLOR CAMERAThe SC30 is an easy-to-use color camera for high-quality microscopy

imaging that offers superior resolution and quality with accurate

color reproduction. Suitable for use in both material and life science

applications, this camera is designed to capture fast frame rates.

Its cost-to-performance ratio makes it a suitable introductory model.

With a native resolution of 2048 x 1532 pixels and multiple binning

modes, the SC30 camera can achieve high levels of sensitivity and

fast frame rates during live cell imaging. Using the 4x binning mode,

49 frames per second can be captured at a resolution of 508 x 384

pixels. Exposure times can be set from 57 microseconds to 1.75

seconds, enabling the user to be in complete control of the image

acquisition process.

Olympus

For information +49-40-2-37-73-5426 www.microscopy.olympus.eu

CYTOMETER FOR LARGE PARTICLESThe Copast Large Particle Flow Cytometers can analyze, sort, and

dispense objects that are too large (20 microns to 1,000 microns) or

too delicate for traditional flow cytometers. Typical samples that can

be analyzed range from small multicellular organisms (C. elegans, D.

melanogaster, and zebrafish) to delicate large cells and cell clusters

(adipocytes, embryoid bodies, pancreatic islets, duct cells, and hepa-

tocytes) to seeds and beads (cells growing in or on beads and bead-

based assays). Samples are analyzed one by one in a continuously

flowing stream and each object is analyzed and sorted based on size,

optical density, and up to three fluorescent parameters. Applications

include rapid dispensing into microtiter plates for assay preparation,

population enrichment prior to further experiments, isolation of rare

events, and quantification of fluorescence levels of each object.

Union Biometrica

For information 508-893-3115 www.unionbio.com

PROTEIN A COLUMNSA new range of Protein A columns combines the benefits of BioVyon

technology with the economy and convenience of a cartridge-based

separation methodology. Designed for laboratories that handle small

numbers of discrete samples, the columns offer a simple and rapid

method for antibody purification, giving consistent recoveries of

purified IgG. The minicolumns have a capacity of about 2.5 mg IgG,

and the microcolumns have a capacity of 200 µg IgG. They can be

washed and reused several times.

Porvair Sciences

For information +44-1372-824290 www.porvair-sciences.com

MICROULTRACENTRIFUGESThe Sorvall Micro-ultracentrifuge models offer versatility in rapid,

small-volume processing of samples, including viruses, cellular or-

ganelles, lipoproteins, nucleic acids, and nanoparticles. Both new

models offer an expanded volume range, accommodating tubes

from 0.2 ml to 30 ml. These systems offer a cutting-edge drive sys-

tem, providing maintenance-free performance and rotor imbalance

protection for years of reliable and dependable performance. The

benchtop Sorvall MTX 150 puts almost any separation within reach

with a centrifugal force in excess of 1,048,000 x g. It achieves its

maximum rotational speed of 150,000 rpm in just 80 seconds, and

features a user-friendly LCD touch-screen interface. The Sorvall MX

series offers the same versatility as the Sorvall MTX 150 in a floor

model configuration. It is available in two versions, with maximum

speeds of 150,000 rpm or 120,000 rpm.

Thermo Fisher

For information 508-742-5254 www.thermo.com/centrifuge

LC TECHNOLOGYThe Accela 600 high performance liquid chromatography (HPLC) and Accela 1000 ultra-

HPLC systems are designed to enable rapid method development and reduce solvent

consumption. Both systems feature Force Feedback Control, which enables the delivery

of accurate and precise gradients under all operating conditions and provides the

flexibility of quaternary solvent delivery. The systems deliver excellent compositional

and flow rate accuracy and precision, resulting in high levels of reproducibility,

according to the manufacturer. When coupled with the Thermo Scientific LTQ Velos,

these systems create a fast LC-mass spectrometry (MS) system, with increased ion

trapping efficiency and lower fragmentation times.The fast scan rates of the LTQ Velos

allow more MSn experiments to be carried out in shorter chromatographic runs.

Thermo Fisher For information 800-532-4752 www.thermofisher.com/lc

Page 15: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

AAAS, publisher of Science,

thanks the sponsors and supporters of the

2010 Annual MeetingBridging Science and Society

18—22 February • San Diego

Presenting Sponsor

In addition generous funding for AAAS Awards is provided by the Kavli Foundation and Affymetrix.

Page 16: INTERNATIONAL SCIENCE & ENGINEERING VISUALIZATION … · 2010-03-05 · netic Analyzers take DNA analysis to an entirely new level of performance. A level where your daily wflw seems

Can you see the mutation earlier?

Can you analyze heterogeneous samples?

Can higher accuracy reduce the coveragerequired to detect SNPs?

Can you reduce the cost and time of validation?

Can true paired-end protocols reduce the noise?

Next-generation sequencing just leaped to the next

level in accuracy. The SOLiD™ 4 System leverages

advanced informatics and optimized reagents to

enable scientist to obtain the highest accuracy of

any NGS system. With throughputs of 100 GB per

run and workflow automation, the SOLiD™ 4 System

accelerates your large-scale genomic analysis to an

unprecedented pace. Plus, new paired-end library

options enable detection of novel splice variation

and fusion transcripts with less input DNA. Using

the SOLiD™ 4 System, your laboratory will have the

ability to detect more variation and spend less time

and money doing it. Take a look at the new SOLiD™ 4

System. See what’s never been seen before.

For Research Use Only. Not for use in diagnostic procedures.©2010 Life Technologies Corporation. All rights reserved. Trademarks of Life Technologies Corporation and

its affiliated companies. All other trademarks are the sole property of their respective owners. Printed in the USA. 01/2010 Publication A-091395 0110

Can you seehow they’llbe different30 yearsfrom now?

Introducing the new,more accurate, higher throughput SOLiD™ 4 System.

SOLiD™ 4SYSTEM SEQUENCING

Formore information, visit us at www.appliedbiosystems.com/solid4