instrumental chemistry
DESCRIPTION
Instrumental Chemistry. Chapter 11 Atomic Mass Spectrometry. Atomic mass. The mass of a single atom, usually expressed in atomic mass units (amu) Most of the mass of an atom is concentrated in the protons and neutrons contained in the nucleus - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/1.jpg)
Instrumental Chemistry
Chapter 11Atomic Mass Spectrometry
![Page 2: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/2.jpg)
Atomic mass
The mass of a single atom, usually expressed in atomic mass units (amu)
Most of the mass of an atom is concentrated in the protons and neutrons contained in the nucleus
Each proton or neutron weighs about 1 amu, and thus the atomic mass is always very close to the mass number (total number of protons and neutrons in the nucleus)
![Page 3: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/3.jpg)
Mass Spectrometers
• Mass spectrometers use the difference in mass-to-charge ratio (m/e) of ionized atoms or molecules to separate them from each other
• In general a mass spectrometer consists of an ion source, a mass-selective analyzer, and an ion detector
![Page 4: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/4.jpg)
Diagram of a Mass Spectrometer
![Page 5: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/5.jpg)
Stage 1: Ionization
• The atom is ionized by knocking one or more electrons off to give a positive ion
• These positive ions are persuaded out into the rest of the machine by the ion repeller which is another metal plate carrying a slight positive charge
![Page 6: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/6.jpg)
Ionization (cont.)
![Page 7: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/7.jpg)
Stage 2: Acceleration
The ions are accelerated so that they all have the same kinetic energy
All the ions are accelerated into a finely focused beam
![Page 8: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/8.jpg)
Acceleration (cont.)
![Page 9: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/9.jpg)
Stage 3: Deflection
• The ions are then deflected by a magnetic field according to their masses
The lighter they are, the more they are deflected
• The more the ion is charged, the more it gets deflected
![Page 10: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/10.jpg)
Deflection (cont.)
![Page 11: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/11.jpg)
Stage 4: Detection
The beam of ions passing through the machine is detected electrically
When an ion hits the metal box, its charge is neutralized by an electron jumping from the metal on to the ion
That leaves a space amongst the electrons in the metal, and the electrons in the wire shuffle along to fill it
![Page 12: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/12.jpg)
Detection (cont.)
![Page 13: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/13.jpg)
Fourier-Transform MS
![Page 14: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/14.jpg)
Magnetic-sector MS
![Page 15: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/15.jpg)
Quadrupole MS
![Page 16: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/16.jpg)
Time-of-flight MS
![Page 17: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/17.jpg)
ICP-MS
Inductively Coupled Plasma Mass Spectrometry
In ICP-MS, the plasma is formed from Argon gas
Plasma is defined as a gas consisting of ions, electrons, and neutral particles
![Page 18: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/18.jpg)
SSMS
Spark Source Mass Spectrometry Semi-quantitative trace element technique for
the analysis of solids and liquid materials Advantages include total simultaneous
elemental coverage, low detection limits, semi-quantitative accuracy (+2-3x), and high resolution capabilities to eliminate many spectral interferences
![Page 19: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/19.jpg)
GDMS
Glow-Discharge Mass Spectrometry Analytical technique for the bulk elemental
analysis of inorganic solid samples The most comprehensive and sensitive
technique available for the analysis of solids
![Page 20: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/20.jpg)
Glow Discharge Ion Source
![Page 21: Instrumental Chemistry](https://reader033.vdocuments.us/reader033/viewer/2022051419/56815c12550346895dc9eece/html5/thumbnails/21.jpg)
Useful Websites Dealing With Mass Spectrometry
• http://www.anachem.umu.se/jumpstation.htm• http://userwww.service.emory.edu/~kmurray/mslist.html• http://www.chemcenter/org• http://www.sciencemag.org• http://reference.allrefer.com/encyclopedia/A/atomMas.html• http://www.webref.org/geology/a/atomic_mass.htm• http://www.chemguide.co.uk/analysis/masspec/howitworks.html• http://www.northernanalyticallab.com/tech2.htm• http://www.shivatec.com/new/gdmsdesc.php4