innate immunity -first line of host defence

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Innate Immunity -First Line of Host Defence Lea Munthe-Fog

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Innate Immunity -First Line of Host Defence. Lea Munthe-Fog. The Complement System is Activated by PAMPs/DAMPS. Lea Munthe-Fog. Recognition of PAMPs/DAMPs by Complement Receptors (CRs). Phagocytosis. Cell type Macrophages Chemotaxis Granulocytes Cytokine storm - PowerPoint PPT Presentation

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Page 1: Innate Immunity  -First Line of Host Defence

Innate Immunity -First Line of Host Defence

Lea Munthe-Fog

Page 2: Innate Immunity  -First Line of Host Defence

The Complement System is Activated by PAMPs/DAMPS

Lea Munthe-Fog

Page 3: Innate Immunity  -First Line of Host Defence

Recognition of PAMPs/DAMPs by Complement Receptors (CRs)

Lea Munthe-Fog

Phagocytosis

Cell typeMacrophages Chemotaxis Granulocytes Cytokine stormMastcells Degranulation T-Cells (?)

Page 4: Innate Immunity  -First Line of Host Defence

Recognition of PAMPs/DAMPs by Toll-Like Receptors (TLRs)

Lea Munthe-Fog

Bacteria

Bacteria

Page 5: Innate Immunity  -First Line of Host Defence

Cytokines and Anti-microbial Peptides are Released in Response to PAMPs/DAMPs

Lea Munthe-Fog

Bacteria

Bacteria