(CLlA WAIVED)

UCPHometrade

Drug Screening Test Cups Test Instruction Questions amp Answers

(Information for the OTC users andji)r hcailh care professional users)

What is UCP Hometrade Drug Screening Test Cups UCP Hometrade Drug Screening Test Cups is a drug screening test and if needed a confirmation service It provides preliminary urine screening results for the detection presence of the following drugs or abuse Amphetaminc Barbiturates Bcnzodiazepines Cocaine Marijuana (THC) Methamphetamine Methadone Ecstasy (MDIvlA) Opiates Opiates 300 Oxycodone Phencyclidine and Tricyclic Antidepressants The test detects any or all of these drugs when they are above the detection limit of the test The test is intended for over-the-counter (OTe) users and for health care professional users

What is the Cut-off level and approximate detection time

I Drug (Identifier) r- Cut-off Level Minimuln T Maximurn 1------------- detectlOJl lime DetectIOn tIme rAmphetamine (AMP) 1000 ngmL 2 -- 7 hOllrs I 2 -- 4 days [ (ucaine (COC) 300 ng-mL i4 hours __ ---2 4 day~

M~thamphctamine (MET) __~~g~~TlI __ ~h~~___J__ 4----zhl~~___==I(gtrasy (MDMA) -L-20 (J n--lIc_ ___l_~_z~i___ ()p~atcs(OPI) I 20()O ngil~~_~~~~___ --l-~~~~~- __ 0plales 300(OPI 300) I 1111 ngiJll[ ill1l1rlt---+ - day

Phencychdme(PCP) ~) ng 1_[___L~_~~r~I_7 l+~gt~ ___________ ~ ~iarijuana (THC) ~lg III I-=- ____~lour~__JJlJ~~) =-c1~~_~_i Ji~llzodiazcpme(BZO) 300 ~~~li_~______U __~~~------1_ ~~ __ __

Methadone(MTD) WO l~gimL I 3 X hours -J ~~t~x~__ -----l Barb~rates(~~________ 300 ngml -+1--4I10----+- i 3 ITb _~

ITricyclit Antjdcprcs~ants(T(A) I 000 l~gmL R --- l~_~~_--i~ - 7 days ___ Oxxcodonc(OX_D _ _____ [110 ngI12_~____3_hl1urs_ [ 1- 2 day---____

The UCP Home 1M Drug Screening Test Cups may not dewct amount of drugs in a urine sample that are below tile cut-off level Evcn th()ugh some level of drug may be present in a urine sample the sample would still be considered a Negative Rcsult if the drug level is below the cut-offlcle

When is the best time to collect a sample The sample should be collected IS soon as possible after suspected drug use Exactly when the urine sampk is collected is very important in dtccting any drug of abuse This is because each drug i cleared hy the body and is deklmiddotted in the urine at different times and rates

How much sample do I need Fill the Drug Test Cup with urine to at least the Illinimum fiillcvellinc hih is approximately 30 mL then 1llthe Ipic Vial to two-thirds (23) full

How do I perform a test with the UCP HomeM J)rug Screening Test Cups I) Begin in a well-lit place Have a watch or timer ready 2) Make sure the urine sample and the Drug Test l~Up is at room temperature before testing 3) Opcn the foil puuch at the nolch and remove the Drug Test Cup 4) Remove the cap from the Drug Test Cup 5) Fill the Drug Test Cup with urine to at least the mininlum till levei line which is approximately about 30 mL it is OK to have some extra urine sample wipe off any splashes or spills on the outside of this cup 6 Place the test cup on a flat dry surfee Stat the timer and lIait for the co (1 red line( s) to appear

7 Read the test result(s) at 5 minutes NEGATIVE RESUlTS A negative result is indicated by two colored lines (of any intensity) one in the control region c AND one in the test region T This result means that the urine screened negative (REMEMBERshyFVEN A VERY FAINT LINE IS A NEGATIVE RESULT)

PRELIMINARY POSITIVE RESlJLTS A single colored line which appears in the control region C and NO line in the test region 1 means the urine screen is considered to be PRELIMINARY POSITIVE The urinc sample must be sent to a laboratory for IlJrther testing More than one test may be preliminary positive INVALID RESULT A test should be considered Invalid Result if no lines appear or if a line appears in the test region T without a line in the control region C The presence of a colored line in the control region C is necessary to confirm assay peril)nllanCe and must always appear (See the illustration in the belOW)

icopy]IJg8~i~~rj-g~rpoundfCJP

I +-Drug Test Name(s)

+- CLine in C Regier

+- TLine in T RegIOn He-K1 results at S mn

c~~R- c~ i

Ttj tJ U TU lHi I NEGATIVe PtXTIVI

POSlTIVf (+)

What dos a negathc lest result mean This means that if the sample was collected properly and if the test was performed according to direction then none of the drugs screened were present in the salllple However if drug use is still suspected you llJay wish to fe-SCreelJ at a later time

What docs a preliminary positive test result mean This mean) that the test has reacted with something in the sample and must be sent to the lab for a morc accurate lest Please review the Test Limitations foilowing this section First and 1110St important BE PlIENT The result you obtained is called preliminary (II a reason The sample MUST be tested by the clinical laboratory in middotliLler to detenninc ira drug of abuse is actually present You will never knov Illr SUfl without ulking the second step

Remember drug screening test is the lirt step in a two step process Step I Screen out (eliminate) the negative samples Step 2 Send any sample which dues nut give a negative result to a laboratory for further testing

Test Limitations I Failure to use this kit as directed may result in an insufficient sample or an inaccurate screcning result 2 This test can he used on urine samples only No other fluids have been cvnluated DO 101 usc this device to test anything but urine 3 The laboratories must receive an adequate amount of sample to perform confirmation testing bull The urine sample is perishable Old urine samples may n01 bc suitable for testing bull Certain foods and medicines diet plan drugs and nutritional supplements may cause a faJse positimiddot lLst llSldt

4 The possibility exists that substances ll1d factors not described in this

instruction may interfere with the tcst causing false results (eg technical or procedural error) bull Adulterated urine samples may produce erroneous results bull Strong oxidizing agents such as bleach can oxidize drug analytes If a sample is suspected of being tampered with a new sample must be ohtained bull This test provides a screening result It is not designed to detennine the aetLial concentration of a drug or the level of intoxication bull Liability is limited to the purchase price of the kit

Mailing a Urine Sample to a Laboratory for Contidential Confirmation Testing If you get a preliminary positive result YOLi need to send the sample to a ecrti ficd Laboratory for confirmation test as soon as possible If you have ohtained a Confirmation Kit from your supplier the kit includes a sample Vial a Confirmation Test Label a specimen bag and pre-addressed mailing box the following steps arc for its use L Ensure that the sample Vial is about two thirds (23) full with the sample and the cap is tightly closed 2 Fill out the Confirmation Test Label for the lab

al Identify thc drug that tested positive on the labeL For example if the screening test indicated the THC was positive mark an X next to the THC lest b) Fill in the blank in Sample Collection Date c-~-=-c---c--

3 Keep the top portion of the label that contains the Identification number and 1-800 toll free telephone number for your record you will need it to obtain the rcsuits 4 Place the Confirmation Test Label onto the side ofthe vial 5 Place the sample Vial into the specimen bag and seal the specimen bag ( Place the sealed specimen bag into the pre-addressed mailillg box Close the mailJl1) box (PLEASE NOTE TIIAT THE MAILING BOX IS NOT PUE-PAI) YOU MUST ATTACH THE PROPER POSTAGE TO HAVE CARRIER SERVICE DELIVER IT) 7 Piace the mailing box in any US Postal Service Ofticc (IT IS IMPORTANT TO MAIL IT RIGHT AWAY Old urine samples may not be suitable for testing 8 Normally you can get the test results in 5 to 10 business days Dial 1-800 toll free telephone numher listed in the top portion of the lahel and identify yourself with the Identification number to receive the test result 9 Test results will be kept on file for thirty (30) days So you must call within thirty (30) day period to receive your test results Remember to have your identification number handy when you calL Results will not be disclosed without an ID number

The following is common street names for sOllie commonly abused drugs

Dl1lg Str~~~ mpildamine Speed am bennie chalk black beauties

Ilakc candy crack blow Cocaine

iYktharnphdaminc I MET Crystal mdh iCL glass Ecqas MDMA I Ecstasy E Adam XIC X Opiates -----------1 OPJ I Heroin H hairy hombre horse jone~ scag Opiates 300 ----j MOR Phencyclidine PCP Angel dust magic dust sherms star dust

Pot weed herb bud MJ doobic reeferMarijuana THe

1 _~sjoint homegrown splitT

Bcnzodiazepine BZO Downers tranks bcnzos Done fizzies chocolate chip cookies joice

Methadone MTD wafer ~ -- shy

Barbs birds red devils yellow jacketsBarbiturates BR

block busters ------ shy~VciC- d TeA() xCt~~~ntI epressants

OXY Oxy killers 0( nxycotton

-------

I What do the laboratory results mean

You will be told if the laboratory tcst result for your urine sample was positive (Of negative according to confinnation testing 2 The results you receive will come from the tests perfonned by laboratory professionals These tcsts are run on very accurate and reliable equipment 3 Positive results are released only when the sample is confinned to be positive using sophisticated techniques and equipment such as gas chromatographymass spectrometry 4 Samples which are scre~nd as negative do not require the second (confirmation) test This can mean several things a) These drugs were used in the past few Jays prior to providing the urine sample Therefore the person either doesnt do drugs or had not done them just prior to resting b) The person may only use a small amount of a drug an amount too small to be detected by the lest c) A person may take a drug that cannot be detected by UCP Homctrade Drug Screening Test Cups UCP Home M Drug Screening Test Cups can only test thirteen (13) drugs and so if any other drugs were in usc the tcst result would be negative d) Thc sample may have been tampered with or be unsullable duc to some raft technical interference 5 Certain j()ods and medicines may cause a rositive test result a) People can test positive for THe (or marijuana) if they have been continually near to very heavy marijuana smoke for long periods of time even though they did not cat or smoke marijuana themselves b) Preliminary positive tests may arise from the cross-reactions with other substances 6 Remember when a drug is found in the urine testing a) docs not tell us how the drug got there (eaten inhaled smoked or injected) b) does not distinguish a prescription medicine from a drug of abuse c) docs not tell if the positive result is from a food that someone ate 7 In the event a positive result for a drug was confimled plcase consult with a proper counselor who can help you It is important thaI you remain calm and do not react in a negative way to the situation 8 I f you have received a positJve result and you do not believe the test result please consult with your physician They will review your background medical history and be ahle to provide you Wilh detailed information on both the test and the meaning of the result

What about False Positive Results A screening test can give a false positive result Certain cross reactive substances are known to occur These can be present due to diet prescription medicines over-the-counter medications etc This is why it is important to send any sample not giving a negative result to the laboratory for further evaluation

Analysis by the laboratory which involves confirmation testing will determine whether or not a drug is present in the urine If the laboratory reports a positive result you may be assured that the drug was indeed present However it would be incorrect to assume the urine sample came from a drug abuser just because the result is positive it is necessary (0 determine how contact with drug occurred

Can False Negative Results Occur If you have observed behavioral changes which you feel could be caused by drug abuse dont discard the suspicion just because the test result is reported negative A false negative result can occur for a number of reasons Certain products are being marketed as a means of defeating drug testing These interfere with various methods used in either the screening or confirmation tests Often the concentration of the drugs in the urine sample is below the cut-otT or sensitivity of the screening assay When this occurs the test is reported negative

(The Following Technical Information and Additional Information for Health C are Professionals)

Performance Characteristics The consumer study was conducted among 110 lay users who had no previous experience using drug testing products The urine samples were prepared to contain strong negative (0 of cutoff) a very weak negative (50 of cutoff) a weak negative (75 of cutoff) a very weak positive (125 of cutoff) a weak positive (150 of cutoff) and high positive (300 of Cutoff) Pure drugs or drug metabolites were spiked into drug free human urine the final drug concentrations in each urine sample were contirmed by GCMS but TCA TCA concentrations in the urine samples was confirmed by HPLC All incorrect results were obtained at drug concentrations between 50 to 150 cutoff levels The test resulb by the lay users are summarized as below

I Drug Cut~~ -F~lt Interpretation --Total-shyI Tet I Agreement

Names (ngmL) I Correct Incorrect h GCIMS -t- WIt l

OM --IOOO- 22R 226 = ii9wshy

I I ~m m j - If--------lI--O-O 22S 24 _4__ 9x2~~ ----j__~i0c0 228 223 5 Q7W--middotf I

300 228 226 2 ---lt591y----l -1000--1228 224 4 9U - shy

+_~~--+-228_-+- 22t 7 9~o -+-_----_+---c2cc2~8 222 6 974

~y IUV 228 6 974m-OPI 2000 22b 222 6 C)74

25 228 225 9X7

1000 228 224 4 982( 50 22~ 224 4 982

Quality Control bull I3uilt-in Control the test contains a built-in control feature the C line The prcsenee of the C line indicates that the test is performed properly I fa Cline docs not i()rm the test is considered invalid Tn this case the testing should be repeated with a new device bull External Quality Control Control materials are not supplied with this kit llowevcr it is recommended that positive and negative controls should be tested as good laboratory practice to confirm the test procedure and to verify proper test performance bull Test each new lot and shipment by using external quality control materials (positive and negative) with each new untrained operator monthly for storage and as otberwise required by your lab internal quality system procedures

Additional information and resources The following list of organizations may be helpful to you for counseling support and resources These groups also have an Internet address which can be accessed for additional information

I National Clearinghouse for Alcohol and Drug lntonnation Web site wwwJlealthorg Phone 1-800-729-6686

2 SAMHSA Health Information Network Web site wwwhealthorg Phone 1-877-SAMHSA-7

3 The national Council on Alcoholism and Drug Dependence Web Site wwwncaddorg Phone 1-800-NCA-CALL

4 The Parents Resource lnstitute for Drug Education Inc (PRlDE) Web site wwwpridcQIg Phone 1-402-397-3309

5 American Council for Drug Education (ACDE) Web site wwwacdeQ[g Phone 1-800-48~-DRUG

Manufactured for lJCP Biosciences loc San Jose CA 95112 USA

8 Read the test results at 5 minutes See thc illustrat ion below For detailed ope ration Ilevmiddot test stri p or device [f the prohlem pers ists ui seont inue using the current lo t (lnd I I )) I (J7 -~ I 9) ) I I ()(y~ () I 97 I I I OO Iolal l onu greement instructions please re fe r to the Procedure Card contact your supplie rs

AnULTERAT10N INTERPRETATION

f- -~ Cap (Please refer to th ~ color chart if applica bl e)

Ur II JIIIIU

sectHI=l middotO T UIM

Testing 0 c -- i1t1---~ Chamber ~ ltJ --~ Ii I u middot c o

~ ~ middotmiddotmiddot--middot~lt J t ~ i -- nne up

I~ 1Ith1lri~lP 1 I I ~ ol)-POltl ~ltIfl~1 ~~sectsectsect~~I ~ label Ottns ~ i

~IOff TeL ~ ~ iii 3 ~ -shy~ -- ) Temperature ______ _ I Strip Labe l

-------~

~ ( 1 111 II (I i(ccc~cc- C~~

11

11~l J I I rl IIrTsalli I I 1 ~ IJ I1 f-~ I_TLineinlRgion 1 ~ R[[ i II

I - I II III Ill l ll I I II IIII~j LI LL LU I I JLJ1JJI

HrugTtNmil ~ II rIf +-Cline inC Region_ ~~-----JI +-TLine if1 T Region ~- h I

i i

f 1IlU 1la l ~n I II ~ r~

iImiddot-middot=--==-~~f Drug Test Names) middot=-~~middotmiddot~lm=ccr 11

-C Line in C Regioll-+ ---- - TLine in T Region I j

lll ~I I ~I ~JLll I J J~ - I NTERPRETATIOI OF RES ULTS Positive One colored line appears in the Control 100t (C ) No line appears in th( Test Zone (T) The a bsence 01 1 line in thc tes t region (T line ) indicates a posi ti ve result The pos iti ve rc~ult indica tes that the drug level is ahovc the dcteitable level Note Th e samples l1 ith e osilive results should hf confi rmed with more specific method Negative Ont colored line appears in the Control zone and another colored line appears in the Test zone The negati ve result indi cates the drug or it s metabolite leve l is be low the de tec table level Invalid No line appears in the Control zone If no C line o r no C line and T line dcv Ll op within 5 to 10 minutes the test is invalid The lest should be repeated w ith a new test dev ice Insufficient spec imen vo lume or the incorrec t procedural techniques a rc the most like ly reasons fo r inva lid result Rev iew the procedure and repeat the lest lIsing a

Semi-quantitative res ult s a rc obta ined by visua ll y comparing the reacted color blocks 0 11

the strip to the printed eo [or b locks o n the color chart No instrume ntation is rcquired QUALITY CONTROL [ Built -i n Control the tes t conta ins a built-in control feature the C line The prcse ne~ of the C line indicates that the test is pe rt(mncd properly If a C line docs not [()In the test is conside red inva lid In thi s case the testing shou ld be rcpeated with a new drug tests 2 Extcrnal QUltll ity Control Controlllla terial s are not supplied vith thi s kit Howeve r it is recommended that pos it ive and negati ve cont ro ls should be tested as good la boratory practice to confirm the tes t procedure and to verify proper test pcrf(mnance 3 Tcst each new lo t and shipment by us ing ex te rna l qualit y control ma teria ls (pos it ive and negati ve) w ith each new untrained operato r monthl y fo r s torage and as o therwi se rcquired by your lab intcrnal qualit y system procedures SVT ADULTERATIONS LIMITATIONS I The adulteration tests included w ith the product arc meant to a id in the determinlt1tion o r abnormal specimens W hile comprehensive these tests arc not mea nt to be an all - inc lusive re presentation of poss ible adulte rants 2 O xidantsPee Normal human urine sholiitl not contain oxidants or pee The presence or high leve ls o f antiox idants in the spec imen s llc h (IS ascorbic acid may resu lt in raIse negative results fo r the oxidantsPeC pad 3 Spce ifie G rav ity U e vated levels o f prote in in urine may cause abnorma ll y hi gh specific gra vity values 4 pH lests ror the presence o f ac idic or alkaline adulte ra nt s in urine Normal pH lew is should bc in the range o f 4 0 to 90 Values outside of thi s range may indicate the sample has been altered 5 Nitrite Nitrite is not a norma l component o j human ur ine Howevcr nitrite I(Hllld in uri ne may indiGltc urina ry trac t infection s or bacte ri a l in lCctions Nit ri le lL vcls o r 20 lllgdL may produce fal se positi ve g l u t~l ra ldc hydc res ults 6 Glutara ltl ehyde is not normall y t() lllld in urine Ilowever certai n mctabolic ahnormaliti Ls such as ketoacidosis ( fas ting umontrolled diabe tes or hig h protein diet s ) may intc rkrc wi th the test resu lts 7 Crea tini ne Normal Creatinine levels arc bc twlcn 20 and 350 mgdL Unde r rare conditions certain kidney di seases lllay shOv d ilut e mine L1MITATlOolS I [)rug Tests (StripCard DlvileCup) pnwides o nl y i1 q1lalitative prel iminary tes ting res ult A more spec ific testing method must be used in order to obtain it Cllll linncd testing result Gas ChromatographyMass Spcc trolllclry (CICMS) is the prefCrred confirmatory me thod 2 T he re is ltI possi bility that tcch nica l or procedural errors as we ll as othe r interfering substances in the urine specimen may cali se e rroneous result s 3 Adulte ra nts SUL h as bleach or othe r ox idi 1ng agents may produce Irroneou s rcs ults If suspec ted the test should be repeated w ith a fresh spec imen and a new drug tests 4 The urine spec imens w ith bmterial contaminat ion sho uld not be llsed for tes ting as these contaminat ions may inter ll re vith the test and ca li se I ~l lse results 5 A positive resu lt does not indicate the levc l of intoxication the rou te of t h ~ d rug administ[(ltion or the concentration oj the drug in the urine O 1 negat ive result may no t necessarily indicate drug-free urin c Negati vL result s ca n be o hta ined w hen drllg is present but hclow the c lit-off level or test 7 Test docs 110t d istinguish between drugs Or abuse and cert a in mcdi ca tions R Certa in I()ods or rood suppl c lllent s may Clt-lll SC a tltllsc posi ti ve result PF RFORMANCF CHARACTERISTIC S Accuracy The comparison stud ies wcrc conducted ll s ing Drug Tests (StripC ard DciceCupl and cOllllllereiall y ava ila bl e rap id drugs of abuse tests The studies were pcrfo nncd on approximate ly 12X c linical specimens plr drug type prev ious collected fro m the clinical settings Presumpti ve posi ti ve results vc rc confi rmed by (iCMS The fo llowing result s a rc summari zed from these comparison studies

Arllmcnl wil h Commcrdal Kit ()t 1~()

1~ l i ~ IO()100 I ()()~~ 9X~ I ()() ~I (J7 iiAcremIH N~gal)I~

IOO l)X~o J7 ~( 100 100 975icrcemenl 11 lt1 ) InoYo l)Kr( 97h lon IlO J7i ~ ft l-n~nK Il (

Page 3 of 5

PoSiliw 9)0 - IO ()O~ 9)0 IIU) Agreement Negativc

9XYo l)X ~ ()X~uiJrecmc1H Illal

lt) Xi I) Jy l)Xh 9i~ trce lllcnl

0 A1rCCml nt with GCMS

Iositlvc IOO(] 9S II JX ~ 97 95 I O(T~ ]00grclllcnl

Ncgaliw 9~ h 100 lJRy lt)7 IO()Yo IPO 971-

~ccmcl1l

rotal l)l) (n5~) l) 1lt ~ nlt~ 10m )9 0

gle~ nllnt

1l1 ~ t T 5(11] OPT

Posi liVi IOU ) )I I()O I () (I ~ lt) 7~- IO(n 100

ltJ r~~mcn l

Tcgaliw I)~ n) 9)0 ()7 ~ 7 100 - IO OLl

Awrcclllctll Illlal

l)9 ~ 97 i 99 j 99 97 I OO) IOO ftc rccrncnl

1(l~ i( ilT 9X 1()O ~O (m~I I ()( ) j

ft lr middot IllCIlI

N CjJ II IT hi Yo ()X~ 9Xft lrmiddotmenl

Iilal )) 9X )()~ ilrollllcIl I

l(II( was I-gta~ld 011 II LC da la HLfI IIUI Ia~ bISlU () Il LcMS da la Sensitivity Sensiti vity o r [)rug Tests (SfripCard ()eviceCup) was charaeterizld by validating the test pe rformance around the c la imed cut-o fr concentration of eac h tes t The cut-orr or each test was determined by the lowest concentration or drug w hi ch produces at least 50) positi ve test ing results in total numbers of detenn inations The result s w ere sllmmarized as the followin g

Ihll--C)IKCI11ral i1I1 AMI woo AM I 100 BAR BZO (lIl-oIT Rangl

O ~ C UI-oIT 211 20 20 20 w -~ OI ( ut-oll 2n 20 20 20 20 2s ( ut-ufl 20 211 Ll 2() 2 11

12SX ClI l -()fl 20 I II 20 211 20 I S() Cut- ll11 20 20 20 21) 20

I )rllg lt(l lllC nlru(i rlll IltJP (()( lot) co( I SO rll (

( Ul-11ffRa ll gc

0 CU h1 1r 20 20 20 211 2(1

O ~ (t it-o il 211 20 20 211 211

-2i C ut-oil 20 20 2() 211 20

12S ( lI l-o ll 211 20 13 20 IX ISO( lI l-oll 20 20 20 211 20

D nJg C(HlCcntralio n M Tf) mA MI loon IIlAM P 500 M[)M A Cu l-oITIange

0 ( ul -oll 20 20 20 20 20

middot iOClll -o lI 20 20 20 20 20

-25 ~ CuI-of 20 20 20 20 20 2i ( u l-off 20 I) 211 20 20

1501 C ul-orl 20 20 211 2n 20

Dril l C(ll1cc ll lral ioll r-tnP 011 OXY PCI CUI -off R ange

o~lt CIII -IIT 20 20 20 20 20 SO CUI-off 2 11 2() 20 20 20 2i~ Cm-oll 20 211 11 20 20 2S ( ut-o ll 20 20 20 17 IS

50 ClIt-ofr 20 20 2 0 20 20

D rllg conccntratioll PI X TCA Cut-ofr Range

OCw-off 2() I 20 I 0 I 20 -50 Clll-ol1 20 I 20 I () I 20

-25 Cut-olT 2() I 20 I 0 I 20

125 Cut-oiT 20 I 4 I Jtgt I 4 I 1(1

t50i Cutmiddotoff 2() l n 1 20101 20

-

--

-

--

---

IIU 7~ 2U (J20 i()l~ middot~II 1) 211 0

Based on above data sensitivity of the assay to the 18 analytes is as folhlvsmiddot 2 2n =F 21X I--n~ Amphetamine lOOO lOOO ngmL Methamphetamine lOOO 1000 ngmt

II -1-1(Amphetamine 300 300 ngmL Methamphetamine SOO 500 ngirnL

li()) 020 Barbiturates 300 nglmL MDMA 500 ngll1L Idhulolll PrccijouR(urodulgtibiJil) Stud) Benzodiazepines 300 ngmL Opiates 300 300 ng IlII ll1h~ld()lIl lutal nunrhtr of Rlulh lrcchinnY) The data prcentcd herc dClllOJllraicgt ccdkllt preCIsion reproducibility or Drug Tc~tBuprenorphine 10 ngmL Opiates 2000 2000 Ilg IllL (middotulHlllllaliu(] (nmL) Ikttmiddotrminatioll l1iI()~

(StripCardUc iClCUU) anus lIHlltiplc conccntrations of human Unlll1 II)()

I IlII Analytical SpclitkityCocaine 300 300 ng rnL Oxycodone 100 ng mL shy

Cocaine 150 150 ng rnL Phencyclidine 25 ng 1111 20 ()() IOjl Cro~s-reac[i it) wa tahh-ohcd by -oplklllg various concentrations of slfllllarly structurcd

Marijuana 50 nglrnL Propoxyphene 300 ng 1111 n II drug cnmpnund inlO drug-frce urllll middota ncgativc control Analyzing ariom conccnlralon Methadone 300 ngmL Tricyclic Antidepressallts IUOO ng 1111 11 II ~II lOll llr each C()lllpllllnd by Ugtlllg Drug Tl t~ (SlripiCardDcviceICup) the conCenlriIIJOIl of

Precision Reproducibility 1lthamntwtamiU 1HUll Preci iollleproducibilit ~IIH thl drug tMt prOdlllId llponlmiddot approxlll1a[cly equivalent to the cut-off t(Hlccntral 1011 or

Reproducibility was determined by replicating tests on five differellt c01lcentration ul ldli3mph(middotlaltlillcl1lU) rot]1 numhtr~ of KllIlh Prcdinn () the a ay lt1lt d[ell1lllllmiddotd Rulh or Ihn Iudillt appear in the tab1c) below each drug in urine specimens negative 50 below cut-otf 25 belo cut-orr 2So( (Hl1nmiddotlllnllillllng 1111) D trminations

=t==1 qIIII -- 11111(

I above cut-oil and 50 above cut- off Each drug test was tested four timc daily for fl c () 1111

- 11111 DrUI(()llIJ)()lJlul J1~PUIImiddotlyuhall1I1 (0 rlll()n~

III) 20 1111consecutive days with a total 20 assays at each concentration The data arc ~u11111ariLLd lIH~middot1 1I~ltIjltlill)() 111(1below )-lllphCLIIllIlK I (J(1I1

20 )1 lllph~11Il1111 Oil

~~~~~ine 1000 Precision IRelroduccibilitLv-Stud-i~_~~~_ _~ 20 ~-llllIILIIIIIIW _ 1I11(lIJ

-Amphetamine 1000 Total numbers of Concentration (n mL) Determinations PreclSlun ( 0) It1hllm()h(tllminc~ SOo Pr(ci~ion iRcprodudbilil Stud- ( )l4middot~klhkllmiddotIIOllll]lliIIITIIII 11)middot

o 20 100 ll1hlrlJphellllnilll soo rotal numbtrs of Kwlh phcdltllcmiddot Inmiddotd~iun (~)

(IIHInlr~lli(J1I (nml) nehrrnjnatioll~ lrkglII~ lliI U111IwllllIllImiddot111)middot1 111(1111111son 20 200 lOW 20 20 () I( II )~ lt) l1PIIlmiddot1 lIrE JUllj 11)750 20 2010 lOll

~() ])lllphcLlllllil 11111250 20 1119 l~ltgt ~(I (I IOO () 1111 DJ middotlIlphlLIITllIlC -~II1500 20 (l20 lOll 1000

1 111[11lt11111111middot(111 100-Amphetamine 30n Precision IRelro-duccibilit=Stu~d-T-__==-__---_ f---~~~ D h-lhdllrpllltlllrlllr~middot~iI II() 1(1(l

Amphetamine 3110 Total numbers of I I 1middotlhnrphmiddotlalllrllmiddot Concentration (n m) )etlrminations 1 lllmiddotI~WIl (0) I ) IlJlmiddotllrlc-lllycmiddotnnlllt)lIllplllLlllIllll 11)middot)

() 20 11111middot ~111 Irllhiorl lc lrndU~tit-cSt~21-Il~--~~-middotmiddotIIlh IIlimiddotiTllr I 01101 I)

1)0 20 1111) (oll(middotulrlliorl (rlgmll Ikllrmination~ iI(middot rll(f~ 1 klhkflldlltnmiddotmiddotlhltlrllllwlIIIIIlIC 111)1 ) llillillill 225 20 1~2 lt)11 20 1111 HImiddotOU It H 11middot- (HH) 175 20 Of2() ]1)(1 2(1 -dIlrgtrl )011 450 20 0i20 1(11) 11 ~II II Il1cmiddotI1IIIIIIil ~O()

~~ 11 II ~II Illlitilliti iOIlBarbiturates PrccisionR~roducibility Study 11 II ~II 1III(hlrmiddotIllrl 100 Barbituratllgt Total numbers of Results ~

111[lil111 Oil

[) 20 200 In() ii~~)~~U Irllii()lIilTE~f~~I~ihilitl~Il~~I~~ 01 I 1~1I11~Conl(ntnllion (II mL) netcrminations Nc IPo~ PUWIIj

Inli~j(ln ((I) 150 20 20iO IO() ( onclnlratiull (ngml) I)ctlrmillrtiolllgt 225 20 200 If)()

BIlhllll 1()1120

J75 20 OJ() IOU )110 IlllllilIhli11 I ~II(Iw ~II 0 1(111 HFNZ( ))1 FPImiddot (O)450 20 (J20 IoU shy II jhlIcp11ll Ilil

Ben70diazepines PrecisionReproducibility Study 11 11 ]1111 1111

BCllzodiazepines rotal numbers of I-Icsults ltI-II)dlIIImiddotL1 nI(1Irnmiddotiioll()

Concenlralion (ngml) Determinations lJcJPos 111)1111middot11111 ~II

20 2010 IIHI ( Irl)ldrImiddotI)()Ik ~II(I

150 20 200 (1111111 11111

20 lOlIl (]IIIlII111 - 20 020 ( )]I middotjlrk 11

450 20 02() 11111 IlcllII(IltllIr 1(1(111

1)IIlI1I1I (lilBuprcnorphinc PrecisionReproducibility Study

11118upnOorphine Total numhers of Rtmlts 1(Tii()1l () IlullrlrltmiddotIdlll 1)11

(hlt)lom (gtrldinnRlpltldudhilit~ tlld~Concentration (n ImL) Hetcrminations llgIPos 111111 IlOI)

(h(OU()JI( rotal IlllmlHn I Rlull - shyo 20 200 00 Pn(iiurl () lldIITIl 101120 200 1110 ( (IIhllltlation (ngml) Ihmiddotllmiddotrmillaliou jlmiddot~

75 20 2(H) 1(11) II IIJ 1110

II 11111

125 20 )~ ) rdItmiddotptlll J()I) =110 ~() ~fJ 11 il IIII I CII1I [I III I ~I)[5 W ILlO (10 ) n ~ (I() lOll 1111011111 )IHI

0 I 7 x~ Cocaine 300 PrecisionReDroducibility Study -17-----t---~l() 00 100 IH IHI ()IHIII1 (IHcI2-1_________+ ______~-------Cocaine 300 Total numhers or R(Sults Iluprmiddotrllgtlplllril jJII(-riiHII(1Concentration (n rot) Uetlrminations ffNcgPos flnlgtllpILTIl)]jlilllC I

() 20 20O IIII I ~

150 20 2UO I IIll

225 20 1()O IIIIIIIIII

375 20 7113 111(1111)11

450 20 020

Cocaine ISO Precision Reproducibility Study Cocaine 150 I Total numbers of Results ~ l ~f 11 ()(Irllmiddotiillll) I)I)(HIIIConcentration (0 lOlL) Determinatiuns ~~~~ Pru)o Jh(lIe Irlri~iOll l~ldllrihili(~~-------0---- shy I IkIIlykmiddottltlllllllmiddot ~ III I

PropO~phlIll rtal IIIllllhlI ul Rl~ult 150 20 200 ~ 11111

o 20 200 I 11111 11 (li~iurl (n ()) I ~Olllllmiddot II( I IIIl()

(onrltration (Ilg mI) 1)lllrlllinatium 1( Po~ I (O( 1rmiddotF 150((0()225 20 HV2 JiImiddot II (1 211 0 11111

tmiddotmiddotmiddot 11----- ~II 2110 11111 ~lllk ~~ ~ ~~~~ -I-__ IkllltlkclSlllllllt ~ - 211 lOll 1111

I q1111ILII(1 1-000 II -11

Mariiuana PrecisionReDroducibilitv Stud 0 HIH C1HC)10 0 011 100 ~Marijuana Total numberlgt of Results - I Illl-~ Illl middotltJ-lmiddot()()j

II lI ~()

-()(I

0211 IO()~

Concentration (n mL) Determinatiuns Ne IPos I-Ihll-middot-I flC-9-middotO()1frinclk ntidqlnmiddotsants l)nlisiolllcplOdIHihjlit~o[~~~ o 20 200 - shy

middotIlttldhdlu~llilldhllwi 25 20 200 ~ ~~~~middotr~)~l~lt II)~tjnriJl~II~I(~(r~ 01 ~~~)~ Inrii()11 (~) bull TfIlhdr)~1I111dhlll(

375 20 200 (I 21l lO() I ()() ( dJItl1blllc11 IO()(I()

Page 4 ofS

-

--

-

--

---

IIU 7~ 2U (J20 i()l~ middot~II 1) 211 0

Based on above data sensitivity of the assay to the 18 analytes is as folhlvsmiddot 2 2n =F 21X I--n~ Amphetamine lOOO lOOO ngmL Methamphetamine lOOO 1000 ngmt

II -1-1(Amphetamine 300 300 ngmL Methamphetamine SOO 500 ngirnL

li()) 020 Barbiturates 300 nglmL MDMA 500 ngll1L Idhulolll PrccijouR(urodulgtibiJil) Stud) Benzodiazepines 300 ngmL Opiates 300 300 ng IlII ll1h~ld()lIl lutal nunrhtr of Rlulh lrcchinnY) The data prcentcd herc dClllOJllraicgt ccdkllt preCIsion reproducibility or Drug Tc~tBuprenorphine 10 ngmL Opiates 2000 2000 Ilg IllL (middotulHlllllaliu(] (nmL) Ikttmiddotrminatioll l1iI()~

(StripCardUc iClCUU) anus lIHlltiplc conccntrations of human Unlll1 II)()

I IlII Analytical SpclitkityCocaine 300 300 ng rnL Oxycodone 100 ng mL shy

Cocaine 150 150 ng rnL Phencyclidine 25 ng 1111 20 ()() IOjl Cro~s-reac[i it) wa tahh-ohcd by -oplklllg various concentrations of slfllllarly structurcd

Marijuana 50 nglrnL Propoxyphene 300 ng 1111 n II drug cnmpnund inlO drug-frce urllll middota ncgativc control Analyzing ariom conccnlralon Methadone 300 ngmL Tricyclic Antidepressallts IUOO ng 1111 11 II ~II lOll llr each C()lllpllllnd by Ugtlllg Drug Tl t~ (SlripiCardDcviceICup) the conCenlriIIJOIl of

Precision Reproducibility 1lthamntwtamiU 1HUll Preci iollleproducibilit ~IIH thl drug tMt prOdlllId llponlmiddot approxlll1a[cly equivalent to the cut-off t(Hlccntral 1011 or

Reproducibility was determined by replicating tests on five differellt c01lcentration ul ldli3mph(middotlaltlillcl1lU) rot]1 numhtr~ of KllIlh Prcdinn () the a ay lt1lt d[ell1lllllmiddotd Rulh or Ihn Iudillt appear in the tab1c) below each drug in urine specimens negative 50 below cut-otf 25 belo cut-orr 2So( (Hl1nmiddotlllnllillllng 1111) D trminations

=t==1 qIIII -- 11111(

I above cut-oil and 50 above cut- off Each drug test was tested four timc daily for fl c () 1111

- 11111 DrUI(()llIJ)()lJlul J1~PUIImiddotlyuhall1I1 (0 rlll()n~

III) 20 1111consecutive days with a total 20 assays at each concentration The data arc ~u11111ariLLd lIH~middot1 1I~ltIjltlill)() 111(1below )-lllphCLIIllIlK I (J(1I1

20 )1 lllph~11Il1111 Oil

~~~~~ine 1000 Precision IRelroduccibilitLv-Stud-i~_~~~_ _~ 20 ~-llllIILIIIIIIW _ 1I11(lIJ

-Amphetamine 1000 Total numbers of Concentration (n mL) Determinations PreclSlun ( 0) It1hllm()h(tllminc~ SOo Pr(ci~ion iRcprodudbilil Stud- ( )l4middot~klhkllmiddotIIOllll]lliIIITIIII 11)middot

o 20 100 ll1hlrlJphellllnilll soo rotal numbtrs of Kwlh phcdltllcmiddot Inmiddotd~iun (~)

(IIHInlr~lli(J1I (nml) nehrrnjnatioll~ lrkglII~ lliI U111IwllllIllImiddot111)middot1 111(1111111son 20 200 lOW 20 20 () I( II )~ lt) l1PIIlmiddot1 lIrE JUllj 11)750 20 2010 lOll

~() ])lllphcLlllllil 11111250 20 1119 l~ltgt ~(I (I IOO () 1111 DJ middotlIlphlLIITllIlC -~II1500 20 (l20 lOll 1000

1 111[11lt11111111middot(111 100-Amphetamine 30n Precision IRelro-duccibilit=Stu~d-T-__==-__---_ f---~~~ D h-lhdllrpllltlllrlllr~middot~iI II() 1(1(l

Amphetamine 3110 Total numbers of I I 1middotlhnrphmiddotlalllrllmiddot Concentration (n m) )etlrminations 1 lllmiddotI~WIl (0) I ) IlJlmiddotllrlc-lllycmiddotnnlllt)lIllplllLlllIllll 11)middot)

() 20 11111middot ~111 Irllhiorl lc lrndU~tit-cSt~21-Il~--~~-middotmiddotIIlh IIlimiddotiTllr I 01101 I)

1)0 20 1111) (oll(middotulrlliorl (rlgmll Ikllrmination~ iI(middot rll(f~ 1 klhkflldlltnmiddotmiddotlhltlrllllwlIIIIIlIC 111)1 ) llillillill 225 20 1~2 lt)11 20 1111 HImiddotOU It H 11middot- (HH) 175 20 Of2() ]1)(1 2(1 -dIlrgtrl )011 450 20 0i20 1(11) 11 ~II II Il1cmiddotI1IIIIIIil ~O()

~~ 11 II ~II Illlitilliti iOIlBarbiturates PrccisionR~roducibility Study 11 II ~II 1III(hlrmiddotIllrl 100 Barbituratllgt Total numbers of Results ~

111[lil111 Oil

[) 20 200 In() ii~~)~~U Irllii()lIilTE~f~~I~ihilitl~Il~~I~~ 01 I 1~1I11~Conl(ntnllion (II mL) netcrminations Nc IPo~ PUWIIj

Inli~j(ln ((I) 150 20 20iO IO() ( onclnlratiull (ngml) I)ctlrmillrtiolllgt 225 20 200 If)()

BIlhllll 1()1120

J75 20 OJ() IOU )110 IlllllilIhli11 I ~II(Iw ~II 0 1(111 HFNZ( ))1 FPImiddot (O)450 20 (J20 IoU shy II jhlIcp11ll Ilil

Ben70diazepines PrecisionReproducibility Study 11 11 ]1111 1111

BCllzodiazepines rotal numbers of I-Icsults ltI-II)dlIIImiddotL1 nI(1Irnmiddotiioll()

Concenlralion (ngml) Determinations lJcJPos 111)1111middot11111 ~II

20 2010 IIHI ( Irl)ldrImiddotI)()Ik ~II(I

150 20 200 (1111111 11111

20 lOlIl (]IIIlII111 - 20 020 ( )]I middotjlrk 11

450 20 02() 11111 IlcllII(IltllIr 1(1(111

1)IIlI1I1I (lilBuprcnorphinc PrecisionReproducibility Study

11118upnOorphine Total numhers of Rtmlts 1(Tii()1l () IlullrlrltmiddotIdlll 1)11

(hlt)lom (gtrldinnRlpltldudhilit~ tlld~Concentration (n ImL) Hetcrminations llgIPos 111111 IlOI)

(h(OU()JI( rotal IlllmlHn I Rlull - shyo 20 200 00 Pn(iiurl () lldIITIl 101120 200 1110 ( (IIhllltlation (ngml) Ihmiddotllmiddotrmillaliou jlmiddot~

75 20 2(H) 1(11) II IIJ 1110

II 11111

125 20 )~ ) rdItmiddotptlll J()I) =110 ~() ~fJ 11 il IIII I CII1I [I III I ~I)[5 W ILlO (10 ) n ~ (I() lOll 1111011111 )IHI

0 I 7 x~ Cocaine 300 PrecisionReDroducibility Study -17-----t---~l() 00 100 IH IHI ()IHIII1 (IHcI2-1_________+ ______~-------Cocaine 300 Total numhers or R(Sults Iluprmiddotrllgtlplllril jJII(-riiHII(1Concentration (n rot) Uetlrminations ffNcgPos flnlgtllpILTIl)]jlilllC I

() 20 20O IIII I ~

150 20 2UO I IIll

225 20 1()O IIIIIIIIII

375 20 7113 111(1111)11

450 20 020

Cocaine ISO Precision Reproducibility Study Cocaine 150 I Total numbers of Results ~ l ~f 11 ()(Irllmiddotiillll) I)I)(HIIIConcentration (0 lOlL) Determinatiuns ~~~~ Pru)o Jh(lIe Irlri~iOll l~ldllrihili(~~-------0---- shy I IkIIlykmiddottltlllllllmiddot ~ III I

PropO~phlIll rtal IIIllllhlI ul Rl~ult 150 20 200 ~ 11111

o 20 200 I 11111 11 (li~iurl (n ()) I ~Olllllmiddot II( I IIIl()

(onrltration (Ilg mI) 1)lllrlllinatium 1( Po~ I (O( 1rmiddotF 150((0()225 20 HV2 JiImiddot II (1 211 0 11111

tmiddotmiddotmiddot 11----- ~II 2110 11111 ~lllk ~~ ~ ~~~~ -I-__ IkllltlkclSlllllllt ~ - 211 lOll 1111

I q1111ILII(1 1-000 II -11

Mariiuana PrecisionReDroducibilitv Stud 0 HIH C1HC)10 0 011 100 ~Marijuana Total numberlgt of Results - I Illl-~ Illl middotltJ-lmiddot()()j

II lI ~()

-()(I

0211 IO()~

Concentration (n mL) Determinatiuns Ne IPos I-Ihll-middot-I flC-9-middotO()1frinclk ntidqlnmiddotsants l)nlisiolllcplOdIHihjlit~o[~~~ o 20 200 - shy

middotIlttldhdlu~llilldhllwi 25 20 200 ~ ~~~~middotr~)~l~lt II)~tjnriJl~II~I(~(r~ 01 ~~~)~ Inrii()11 (~) bull TfIlhdr)~1I111dhlll(

375 20 200 (I 21l lO() I ()() ( dJItl1blllc11 IO()(I()

Page 4 ofS

--

ClIlnabid101 100000 Ir IIIAlJOE (ITU) Methao()n~ 300 (plusmn)2-Hhyl-1 yrrolinium 50000 I)oxylamine 50000 MfiTHAMPHfiTAlINfiS 1000 (mAllMET ~ i-Methamphetamine 2000

+Methamphetamine 1000 3A~MlhylCI]_I_~_~_~ycthV lamphettllline( MDF A 1 35000

( i-nA-Jldh kncdiuxYll1cthall1phetall1ine n 2000 I-all itidine(Zantac) IllU(I(l()

I-Methylenedioxyamphetami~~JMPl~) IOOlOn D-mphetamine 1 nuooo L-AITIphetamine IOGOOO lphcdrinc In()()ou

1 ETIIAMPHETAMINES 500 (mAMPJI FT) I I ) r-dethanlllll(tJllHl I(J()O

I I 1ctha~ctaminc O(J

I I ) _l4-Mcthylcnedioxymcthamrhctamine (r-l1 )10) I()on

1lllldinc (Zantac) gt 1()()O(j()

i -1--Methylcnedioxyamphctaminc (MDA) gt I()()(j(l(j

J) nphetaminc gt(J(ljll)(1

L-Amnhelamine 100000

Ephedrine gt 100000

I MEn~_X~_~EBI()XY_~_l_~TlIA_lPIIKrAi1INE (M[)MA) (I i-)34-lvklhylemdlOxymdhamrhetarnlTlc (MOMA) 500

D-Amphdalllllle gtIOO()OO

L-ktlalllphdalllllll 100000

34-Melh IcnedlOxydhylamphdallllllc (MDFA) 200

3A-MelhylcllltdlOxYltUllphdammc (ro11)) 20()()

OPIATE JOO (lotOPI JOU)

Morphine 300 Codeine 300 II ydWC(lJOlle 2000

11 dlOmorphone 15()(

lllIJhinc 3-ll-D-glucuronide i(lO

( r-l(moltlcetylmorphinc hll()

JllOrphonc 11l()()OII

()xlodonc l(lIl(j(l

Ox morphonc illlln(1

j l1lhainc -(jOO

UI-uTE 2000 (OPI 2(00) j(lr1hine JjlO

(lkine ~ IIcil-ocoltonc I()()()()

______ 7000 ______-1 ~lI~I~~r~~ll~~_gl ucuro n id e 20(H)

6- M 0 noac lyITHl rph inc IOO()

NOrll(lIpl](lllL IOO()OO

20000

100000 TIlCnaill( 70()()O

OXYCOnO~E (OXY) ()xycod(lIle 100 1orphllle SO()()O

~odcill 2S()OO

Mnrphin J-ll-Il--gI11Lllmnid 50000

IlydrueudoJlL 16(10 li(l()()

NlllllOrphone I (j()(I()()

~II~~~~~~~IDI~n (PCP 1~()()---------1 hclleyclidinc

I-Ilydroxyphcncyclidine IIJI)(

IIOPOXYPHENE (PPX) InlJlIlxyphene Oil

i1)rpropoxyphcne i(11l

r-klhadonc - I11Il(IOiJ

11I_clCIIC ANTIDEPRESSANTS (TC) N(llrl~tiIine I(lOll

rllIlipraminc -1-~()()

AmitriptylinL 1000

Iromaine 1000

~ram_il_I_1 1000 Imipramine 1000

~_rralinl 7S()0 Ooxepin 30()()

Maprolilmc 50000

Interfering Compounds The following compounds ill both drug-free urine and drug positive urines with Amphetamine Barbiturate 13enzodiazcpinc BuprenorphjIK~ Cocaine Marijuana flcthadone Methamphctamines flilt)-Il1cdioxymethampllLlamine ()ptatc Oxycodnllc

Phencyclidine Propoxyphenc Tricyclic Antidepressants show no cross-rLlClivity when tested vith Drug Tests (StripCardDeviccCup) at a concentration of 100 lIgimL

Common Substances Aeelatlltllopilln Diphenhydramine ( t-i_)-Norcrilcdl-Ine

Acetone Dopamine Oxalic Acid

Albumin ( i-)-Epmcphrine Pcnicillin-(

Ampicillin Lrythromyein Iheniramll1c Acmhic ictd Ethanol Ihenothlanlllt

Aspartame 11I11el]]lck I-Phcnvlephrim Aspirin (jltkU~L p-Phenylethylamine

Atropine (jUIIIU] (jl)Llryl Llher Procaine Benzocaine Ikl1l)~I(lhll Quinidine

Bilirubin IhljlnJcn Ranitidine

Caffeine -)-Ipru1cITHgtl Riboflavin

Chloroquine K-lllnine Sodium Chloride ( f )-Chlorphcniramine lLorpilllwl Sulindae-shy

( +I-)-Chlorpheniramine Creatine (~J~I_~~i~~~~Xl -c~~~~rll11~e~iC-middot--------1 Dcxhrompheniramine Jiaeimllnidc I 4-Dimelhylaminoanlipyllll

Dextrometh~an Nic(ltinc I (IR2S)-(-)-N-Melhyl-1 pllIl

Biological Vlatcrhtls Albumin I Vitamin(L-Ascorhic Acid) Bilirubin I Uric Aeid (rcatine Urine pH 45-90

I ~CllT1ogl()hitl Urine Specific Gravity 1_()()2-1035 gml (I Hense

(There is (I wsihility that other suhslanccs andlorjclCtoS Iot listed ahove may inlerjere with the test und (Wlseillse results)

Bibliography L Basch RC Disposition ul 1(lc Drugs and (hel1l1lals III Man 4 lhEd Biomedical Pub fhj- (_

1995 2 Department of Health and UlIldll Sln iltc Ll11dli(lry (juidc1ines for Federal Workplltlcc Drtl~ -I c~liJlu Program Fed Register 53laquo(l()) II PO J I(J7l) I()-(X

3 Gilmltlll A G and (ioodmall 1_gt Ihc phlImlloi(gical basis of therapeutics Ed 11acftllall Publishing New York NY 19l-0 4 Urine Testing for Drugs of AbuCl LtI]())Iti lllCllllllL 011 Drug Abuse (NIDA) Research Monpgllpll

1986 5 Wilson John Abused 6 Cody JT Specimen 7 TsaL SoC et_aL 1_ Ami s TielI lW Textbook oft Iinical ChcmistryVBSautukrs (middoto1llpilny19X6 I TJj

Rcj~cd larch 20lJ

Page 5 of 5

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