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Increasing access to diarrhea treatment in India: Building demand for zinc and ORS among caregivers and providers Request for Proposal September 2012

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Page 1: Increasing*access*to*diarrheatreatmentin*India:*...Recent scientific advances have informed these revised recommendations. They are: • Development of an improved formula for ORS

Increasing  access  to  diarrhea  treatment  in  India:  Building  demand  for  zinc  and  ORS  among  caregivers  and  providers    Request  for  Proposal      

 September  2012  

Page 2: Increasing*access*to*diarrheatreatmentin*India:*...Recent scientific advances have informed these revised recommendations. They are: • Development of an improved formula for ORS

Agenda  

2  

•  RFP  

•  Background  

•  GeneraAng  demand  among  consumers  and  providers    

Agenda    

Page 3: Increasing*access*to*diarrheatreatmentin*India:*...Recent scientific advances have informed these revised recommendations. They are: • Development of an improved formula for ORS

RFP        

 

Page 4: Increasing*access*to*diarrheatreatmentin*India:*...Recent scientific advances have informed these revised recommendations. They are: • Development of an improved formula for ORS

The  Request    

•  Respond  to  the  connecAons  brief  –  ConnecAons  Idea  –  Top  level  channel  plan      –  Budget  split  recommendaAons  –  Develop  rural  household  profile  –  Develop  rural  mum  profile  –  Develop  rural  medical  pracAAoner  profile  

 •  Timings  for  launch  for  2013  diarrhea  season  

•  Cost  Proposal  for  partnering  with  CHAI  to  develop  and  implement  the  project    

•  Staffing  proposal  for  partnering  with  CHAI  to  develop  and  implement  the  project    

•  Provide  an  overview  of  agency  credenAals  relevant  to  the  current  project  

4

Page 5: Increasing*access*to*diarrheatreatmentin*India:*...Recent scientific advances have informed these revised recommendations. They are: • Development of an improved formula for ORS

CHAI  will  evaluate  agencies  based  on  the  following  criteria:    Primary  •  Demonstrated  knowledge  of  the  target  markets  •  ConnecAon  and  communicaAon  plan  that  clearly  demonstrates  how  it  will  

create  the  desired  behavior  change  in  the  target  markets    –  We  are  looking  for  a  3-­‐year  plan  but  your  response  should  provide  most  detail  for  2013  

•  Demonstrated  passion  and  commitment  to  go  above  and  beyond  to  help  CHAI  deliver  its  aggressive  goals  to  save  lives,  including:  –  Compelling  cost  savings  vs  commercial  clients  –  Helping  CHAI  to  galvanize  and  excite  exisAng  and  potenAal  partners,  including  local  

government  to  commit  significant  addiAonal  resources  to  the  cause    

Secondary    •  Ability  to  implement  similar  communicaAon  programs  in  other  CHAI  focal  

countries  (Kenya,  Nigeria  and  Uganda)  and  create  addiAonal  leverage    

5

Criteria  for  selecAon    

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Milestone   Timing    

CHAI  briefing  to  agency   September  10  (Mon)  

Response  from  agency   September  27-­‐28  (Thurs-­‐Fri)  

EvaluaAon  of  responses     October  1-­‐4  (Mon-­‐Thurs)  

Agency  selected   October  5  (Fri)  

6

Timing    

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•  It  is  expected  that  your  agency  will  deliver  a  compelling  presentaAon  to  the  CHAI  team  in  person  in  New  Delhi  on  September  27th  (Thursday)  or  28th  (Friday).  

•  You  will  have  a  maximum  of  2  hours  to  deliver  the  presentaAon  as  well  as  allow  for  quesAon  Ame.  

•  You  should  provide  a  printed  and  digital  copy  of  the  presentaAon  on  the  same  day  including  all  the  key  informaAon.  

•  Copies  of  presentaAons  for  parAcipaAng  agencies  who  are  not  selected  will  be  destroyed  by  October  5th  (Friday)  

•  ParAcipaAng  agencies  (selected  and  non-­‐selected)  will  be  informed  by  October  5th  (Friday)  

7

ConfidenAality  and  applicaAon  process    

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Background      

 

8

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Almost  one  in  three  child  deaths  is  due  to  pneumonia  or  diarrhea,  claiming  almost  3.3  million  lives  each  year…  

| 9  

18%  

15%  

 8    2%  

36%  

21%  

Pneumonia  

Diarrhea  

Malaria  

HIV/AIDS  Neonatal  causes  

Other    (measles,  pertussis,  

injuries,  etc.)    

ProporAonal  distribuAon  of  cause-­‐specific  deaths  among  children  under  five  years  of  age,  2011  1    

…but  a  disproporHonate  amount  of  global  funding  has  been  allocated  to  treat  other  diseases  

~3.3million  U5  deaths/year  from  diarrhea  and  pneumonia  alone  

Pneumonia  and  diarrhea  remain  the  two  largest  killers  of  children…  

Source:    Black  R,  Cousens  S,  Johnson  HL,  Lawn  JE,  Rudan  I,  Bassani  DG,  et  al.  Global,  regional,  and  naAonal  causes  of  child  mortality  in  2008:  a  systemaAc  analysis.  The  Lancet.  2010;375:1969-­‐87;  World  Malaria  Report  2011,  Global  Fund  Disbursements  in  Detail;  PEPFAR  OperaAonal  Plans  FY  2007-­‐2010;  USAID,  Introducing  Pediatric  Zinc  with  ORT/ORS  in  the  Private  Sector  ,  MeeAng  report,  August  2010  

~6,500  

 ~1,300    

 14.8    

HIV/AIDS   Malaria   Diarrhea  

US$  millions,  between  2007-­‐2011    

Zinc  scale-­‐up  in  8  countries  

ACT  treatment,  CommunicaAon  &  advocacy,  training  (Global  Fund  &  PMI)  

HIV  Treatment  (Global  Fund    &  PEPFAR)  

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With  the  leadership  of  the  UN  Commission  on  Life-­‐Saving  CommodiAes  for  Women  and  Children,  there  is  an  opportunity  to  catalyze  change    

| 10  

•  The  Goal:  Save  lives  of  children  dying  from  pneumonia,  diarrhea  and  malaria  and  accelerate  progress  towards  MDG4  by  improving  access  to  available  treatments  

•  By  2015:  60-­‐80%  coverage  of  diarrhea,  pneumonia  and  malaria  treatment  for  children  under  five  

 •  By  end  2012:  Concrete  progress  towards  this  goal  in  all  ten  priority  countries  

   

Across  10  high-­‐burden  countries:  

UN  Commission  Advocates  at  the  highest  levels  to  catalyze  change  

 

Chairs:  Pres.  G.  Jonathan  of  Nigeria  PM  J.  Stoltenberg  of  Norway      

   Technical  Working  Group  (3  Themes)  Supports  the  Commission  to  examine  barriers  to  scale-­‐up  

Diarrhea  &  Pneumonia  Working  Group  

Translate    Commission  recommenda@ons  into  ac@ons  for  countries  

Iden@fy  barriers  to  scale-­‐up  and  translate  country  needs  into  concrete  decisions  for  Commission  

Leadership  Structure  and  Roles    

“Making  sure  that  women  and  children  have  the  medicines  they  need  is  cri@cal  for  our  push  to  achieve  MDGs”  Secretary-­‐General  Ban  Ki-­‐Moon  

Provides  near-­‐term  support  to  countries  in  efforts  to  scale-­‐up  access  to  treatment  

Vice-­‐chairs:    UNFPA  UNICEF  

Market  shaping  

Regulatory  environment  

Best  pracHces  &  innovaHons  

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To  date,  the  UN  Commission  has  launched,  and  the  10  priority  countries  have  developed  naAonal  plans  to  catalyze  treatment  scale-­‐up  

| 11  

Q1   Q2  Q3   Q4  

2011   2012  

Progress  to  date    • Global  taskforce  created  •  Scale-­‐up  plans  finalized  for  10  priority  countries  (lead  by  govt./local  partners  with  support  from  working  group)  

• UN  Commission  launched  

Q2  2012  and  Ongoing  • Resource  mobilizaAon  •  ImplementaAon  of  naAonal  plans  in  10  priority  countries  

ü     

India Kenya Nigeria Uganda DRC Bangladesh Ethiopia Niger   Pakistan Tanzania

Page 12: Increasing*access*to*diarrheatreatmentin*India:*...Recent scientific advances have informed these revised recommendations. They are: • Development of an improved formula for ORS

Measels  4%   Diarrhea    

13%  

Malaria    1%  

Pneumonia  20%  

Prematurity    14%  

Birth  Asphyxia  10%  

Neonatal  Sepsis  6%  

CongeniAal  anomalies    

3%  

Injuries  3%  

HIV/AIDS  1%  

Others  25%  

246m  episodes/year      ~225,000  deaths/year  

ProporAonal  distribuAon  of  cause-­‐specific  deaths  among  children  under  five  years  of  age,  2010    

Source:    World  Health  StaAsAcs    2011  www.who.int  District  Level  Household  and  Facility  Survey  2007-­‐08  

12

In  India,  ~225,000  children  die  every  year  due  to  diarrhea  

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3

JOINT STATEMENTMore than 1.5 million children under five continue todie each year as a result of acute diarrhoea. Thenumber can be dramatically reduced through criticaltherapies such as prevention and treatment ofdehydration with ORS and fluids available in thehome, breastfeeding, continued feeding, selective useof antibiotics and zinc supplementation for 10–14 days.

These new recommendations, formulated by UNICEFand WHO in collaboration with the United StatesAgency for International Development (USAID) andexperts worldwide, take into account new researchfindings while building on past recommendations.Success in reducing death and illness due todiarrhoea depends on acceptance of the scientificbasis and benefits of these therapies by governmentsand the medical community. It also depends onreinforcing family knowledge of prevention andtreatment of diarrhoea, and providing information andsupport to underserved families.

PROGRESS AND CHALLENGESNEW DEVELOPMENTSRecent scientific advances have informed theserevised recommendations. They are:

• Development of an improved formula for ORSsolution with reduced levels of glucose and salt,which shortens the duration of diarrhoea and theneed for unscheduled intravenous fluids1

• Demonstration that zinc supplements given duringan episode of acute diarrhoea reduce the durationand severity of the episode2, and

• Findings that zinc supplementation given for 10–14days lowers the incidence of diarrhoea in thefollowing 2–3 months3

Many more lives can be saved if these advances areused in conjunction with effective home treatmentand use of appropriate health services. To be mosteffective, these revised recommendations mustbecome routine practice both in the home and health

facility. (See the Technical Annex on page 6 foradditional details.)

BUILDING ON PAST SUCCESSESORS, ORT and other components of clinicalmanagement of diarrhoea have made a significantcontribution to reducing deaths from diarrhoea.However, if the global goals are to be met, there is stillmuch to do.

Family knowledge about diarrhoea must be reinforcedin areas such as prevention, nutrition, ORT/ORS use,zinc supplementation, and when and where to seekcare. Where feasible, families should be encouragedto have ORS ready-to-mix packages and zinc (syrup ortablet), readily available for use, as needed.Breastfeeding should continue simultaneously withthe administration of appropriate fluids or ORS.

ORS  included  in    stakeholder  guideline    

Zinc  included  in    stakeholder  guideline  

Indian  Academy  of  Pediatrics  (IAP)   ✓   ✓  Indian  Medical  AssociaAon  (IMA)   ✓   ✓  Integrated  Management  of  Neonatal  and  Childhood  Illnesses  (IMNCI)    

✓   ✓  

NaAonal  Rural  Mission  (NRHM)1   ✓   ×  

NaAonal  Program  for  Treatment  of  Diarrhea    

✓   ✓  

NaAonal  EssenAal  Medicines  List     ✓   ✓  

13

ORS  and  zinc  are  simple,  highly  effecAve  and  affordable  and  is  recommended  by  key  global  and  local  stakeholders  to  treat  childhood  diarrhea    

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Treatment  of  diarrhea  in  children  under  five,  percentage,  esAmates  

The  Challenge     Diarrhea  treatment  seeking  behavior      Percentage,  esAmates  

However,  most  paAents  do  not  access  the  recommended  diarrhea  treatment:  zinc  coverage  remains  dismal,    yet  offers  an  opportunity  for  impact  

The  Opportunity    

~35  

~35  

~29  

Home  or  No  treatment  

Treated      with  anA-­‐  bioAcs  /    other  

Treated      with  ORS    

Treated  with  Zinc  &  ORS  

~1  

Number  of      cases  of  diarrhea  

 246  mln  cases  of  diarrhea  in  India  /  

year     The  Opportunity  

SOURCE:  WHO;  Private  Healthcare  in  Developing  Countries:  www.ps4h.org/globalhealthdata.html;  Fischer  Walker,  Cynthia  et  al.  The  Global  Burden  of  Childhood  Diarrhea.  Maternal  and  Child  Health:  Global  Challenges,  Programs,  and  Policies.  Ed.  John  Ehiri.  New  York:  Springer.  2010;  Fischer  Walker  et  al;  Scaling  Up  Diarrhea  PrevenAon  and  Treatment  IntervenAons:  A    Lives  Saved  Tool  Analysis,  2011.    

District  Level  Household  and  Facility  Survey  2007-­‐08  Larson,  C,  et  al.  Scaling  up  zinc  treatment  of  childhood  diarrhoea  in  Bangladesh,  Health  Policy  and  Planning,  2011  

Private  Sector  45%  

Public  Sector  21%  

Home  or  No  

Treatment    29%  

Others    5%  

14

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The  Indian  Diarrhea  Treatment  Market:  Products  and  Availability          

 

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•  Tablet  and  syrup  (50  &  100ml)  •  Dosage  =  1/day  for  14  days  •  Syrup  =  5ml/day  for  14  days  •  Reduces  stool  volume  over  a  couple  of  days  

•  24%  reducAon  in  Ame  to  recovery  •  Reduces  likelihood  of  another  episode  for  3  months  

• Higher  price  point  • OTC  expected  by  September  2012  

•  Available  in  powder  sachet:    •  5g  =  200ml  and  20g    =  1  litre    •  Dosage  =  50-­‐200ml  arer  each  stool  depending  on  age  of  child  

•  Various  flavours  available  •  Decreases  vomiAng  •  Efficient  rehydraAon;  replenishes  electrolytes    

• Higher  price  point  • Mixed  availability  

ORS  

•  Injectable,  oro-­‐dispersible,  crushable,  syrup  

•  Dosage  =  1-­‐2  tab  per  day  •  Pharmacist  can  cut  blister  and  supply  1-­‐2  tabs    

•  Does  not  stop  diarrhea  • Widely  available  •  Low  price  point  (30-­‐40  rupees/3  days)  

•  Treat  cholera  and  dysentry  

AnHbioHcs  

•  Tablet    and  syrup  •  Dosage  =  1  tab  only  once  •  Pharmacist  can  cut  blister  and  supply  1-­‐2  tabs    

•  Stops  diarrhoea  quickly  • Widely  available  •  Very  low  price  point  (1-­‐2  rupees/tablet)  

 

AnH-­‐diarrheals  

Features  

•  Child  doesn’t  suffer  from  dehydraAon  •  Stops  the  child  from  geung  worse  –  may  not  need  to  see  and  pay  for  HCP  

•  Child  recovers  more  quickly  and  has  more  energy  

•  20%  reducAon  in  stool  output  •  30%  reducAon  in  vomiAng  

•  Can  always  obtain  •  Affordable  

•  Immediate  relief  (for  mum)  •  Can  always  obtain  •  Affordable  

Benefits  

Zinc  

•  Stops  the  child  geung  worse  • Quicker  recovery  •  Stronger  child  • Healthier  child  

•  Does  not  help  dehydraAon  •  Does  not  stop  diarrhea  •  Long  term  use  =  resistance  to  anAbioAc    

•  Does  not  help  dehydraAon  •  Causes  consApaAon  –  causes  distension  of  the  gut  and  possibly  pain?  

•  Does  not  reduce  frequency  of  stool  output  

• Not  as  affordable  •  Child  needs  to  drink  a  lot  of  fluid  regularly  

• Not  as  affordable  • Need  to  remember  to  dose  for  14  days  

16

Issues  

Products  currently  used  to  treat  child  diarrhea:  features  and  benefits  

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ORS  powder  and  Zinc  syrup  are  currently  the  most  common  formulaAons  purchased  in  the  Indian  market    

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49.4  

12.6  

38  

7.7   5  

87.3  

Currently  stocking     Currently  not  stocking     Never  stocked    

ORS  

Zinc  

Availability  of  ORS/zinc  at  the  retail  level    Study  in  4  districts  in  Uxar  Pradesh;  n=300  

Reasons  for  not  stocking  ORS:    •   35%:  Low  demand    •   15%:  Low  profit  margin    •   10%:  Not  aware  of  ORS  

   

Harmfully  low  

availability  of  zinc  

Reasons  for  not  stocking  zinc:    •   83%:  Not  aware  of  zinc  •   7%:  Low  demand  

   

18

There  is  limited  availability  of  the  products  at  the  retail  level,  due  to  a  lack  of  awareness  about  the  products    

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The  Indian  Diarrhea  Treatment  Market          

 

19

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•  ORS/zinc  is  recommended  by  global  (WHO  and  UNICEF)  and  local  stakeholders  (IAP,  IMA)  

•  Good  local  manufacturing  capability  •  Partnerships  with  GoI  and  others  working  on  diarrhea  treatment  (e.g.,  FHI360,  MI,  PSI)  

Strengths  to  Leverage  

•  Diarrhea  not  perceived  as  a  serious  illness  •  Lack  of  perceived  efficacy  (symptom  relief)  of  ORS    •  No  perceived  differenAaAon  between  ORS  and  home  remedies?  

•  High  perceived  efficacy  of  anAbioAcs/anA-­‐diarrheals  •  Belief  that  ORS  is  difficult  to  prepare  •  Belief  that  ORS  needs  to  be  given  too  frequently  and  too  high  a  volume  for  the  child      

•  Mum  will  not  give  treatment  without  HCP  advice  •  Poor  compliance  to  14  day  course  of  zinc  •  Supply  chain  views  ORS/Zinc  as  low  volume  

Weaknesses  to  Neutralize  

•  Current  low  awareness  of  zinc  among  caregivers  and  HCPs  

•  RMPs  comprise  60%  of  total  HCP  visits  and  are  hungry  for  informaAon  

•  Low  availability  of  ORS  and  zinc  beyond  Class  1  &  2  towns,  represenAng  opportunity  for  growth  

•  OTC  status  for  ORS  and  expected  soon  for  zinc  •  Growing  poliAcal  axenAon  on  diarrhea  •  Several  key  bodies  (including  NRHM)  are  yet  to  include  Zinc  in  their  guidelines  

•  ExisAng  provider  outreach  models  (FHI360,  MI)  

OpportuniHes  to  Capitalize  on  

•  ConAnuity  of  program  post  2015  

Threats  to  Combat  

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ORS  and  zinc:  SWOT  analysis    

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Building  caregiver  and  provider  demand  for  zinc  and  ORS          

 

21

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ObjecHve:    To  increase  usage  of  ORS/zinc  from  <1%  to  50%  in  three  states  by  end  of  2015    

Geographic  focus:  Madhya  Pradesh,  Uxar  Pradesh,  Gujarat    

DuraHon:    July  2012  –  Dec  2015    

 

Ugar    Pradesh  

         Gujarat  

   

Madhya    Pradesh  

Key  Program  Components:  

1)  Generate  demand:    Target  consumers/providers(HCP’s)  based  on  analysis  of  most  effecAve  messages  and  communicaAon  channels;  developing  creaAve  soluAons  to  reach  beyond  tradiAonal  urban  markets  

2)  Catalyze  poliHcal  will:  Mobilize  and  harmonize  investments  from  governments  and  partners  toward  state-­‐wide  scale  up  goals  

3)  Ensure  supply  of  zinc/ORS:    Ensure  wide-­‐spread  availability  of  affordable,  high-­‐quality  products  in  public  and  private  sector  

The  3  states  represent  nearly  half  of  naAonal  diarrhea  burden  –  with  over  164K  deaths  annually  

Specifically,  CHAI  aims  to  increase    usage  of  ORS/zinc  from  <1%  to  50%  in  three  states  by  end  of  2015  

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The  Key  Problem:  

•  Mums  don’t  believe  that  diarrhea  is  a  serious  illness.  They  do  not  believe  that  it  can  harm  their  child.    

•  They  watch  and  wait  for  several  days  unAl  the  condiAon  worsens,  before  they  will  go  and  visit  their  front  line  healthcare  provider  (HCP).  

•  Once  they  do  visit  their  HCP,  they  have  come  to  expect  that  they  will  be  given  medicaAon  that  will  stop  their  child’s  diarrhea  within  a  day.  

•  HCP’s  believe  that  anAbioAcs  and  anA-­‐diarrheals  are  the  best  treatment  for  diarrhea  to  saAsfy  these  paAent  expectaAons  

The  key  problems  we  need  to  solve:  

23  

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Defining  our  Target  Market  Who  do  we  need  to  reach  to  save  the  most  lives?        

 

24

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Across  the  focal  states,  the  vast  majority  of  the  diarrhea  deaths  among  children  (>80%)  are  in  rural  areas  –  with  over  half  in  rural  UP  alone  

4%  

23%  

11%  54%  

2%   6%  

%  and  number  of  U/5  diarrhea  deaths  in  focus  area  

Na@onal  Family  Health  Survey  (NFHS-­‐3)  2005-­‐06    

Madhya  Pradesh  

Urban

Rural

Urban

Urban Rural

Rural

Gujarat  

Ugar  Pradesh  Total  Urban:  17%  

Total  Rural:  83%  

Agency  to  advise  on  potenAal  reach  of  communicaAons  

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27    CiHes  

398    Towns  

4,738    Peri-­‐urban  

600,000    Villages  

AdministraAve  Structure  in  India  Source:  NovarAs,  Aroygya  Parivar,  November  2010    

DistribuAon,  detailing  and  communicaAon  of  ORS/Zinc  has  been  limited  beyond  Class  1  and  Class  2  towns  

Key  Focus  to  Date:  33%  of  the  market  

Opportunity:  67%  of  the  market  

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Understanding  the  profile  of  rural  households  will  be  essenAal  to  success  

Uxar    Pradesh  

         Gujarat  

   

Madhya    Pradesh  

Ugar  Pradesh  –  75%  Rural:  •  42%  illiterate  (higher  for  women)  •  78%  have  no  television  •  84%  no  access  to  a  toilet  •  69%  of  children  axend  some  school  •  87%  some  sort  of  immunisaAon  

 

Madhya  Pradesh  –  72%  Rural:  •  45%  illiterate  (higher  for  women)  •  80%  have  no  television  •  90%  no  access  to  a  toilet  •  69%  of  children  axend  some  school  •  77%  some  sort  of  immunisaAon  

Gujarat  –  58%  Rural:  •  36%  illiterate  (higher  for  women)  •  62%  have  no  television  •  70%  no  access  to  a  toilet  •  71%  of  children  axend  some  school  •  85%  some  sort  of  immunisaAon  

 

Na@onal  Family  Health  Survey  (NFHS-­‐3)  2005-­‐06    

Agency  to  expand  on  the  rural  household  profile  

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Defining  our  Target  Market  Who  are  these  people  that  we  need  to  reach?        

 

28

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Demographics:  • Age:  18-­‐29  • Illiterate  • Axended  school  for  a  couple  of  years  • Live  in  2  room  house  • Water  obtained  from  pump  in  the  village  • Income?    • Electricity?  

Key  Influencers:  •  Healthcare  professional  •  Mother  in  law  •  Husband  •  Educated  female  member  

of  community  

Daily/Weekly  AcHviHes:  • May  visit  Haat  or  town  once  a  week,  but  more  likely  that  the  husband  goes  

• Community  centre?  • How  oren  visit  pharmacy?  • Visit  with  friends/neighbours?  • RelaxaAon  Ame?  

Diarrhea  History:  Has  the  mum  had  much  experience  with  diarrhea?  

Key  Insight:  “Diarrhea  is  a  bit  annoying  and  inconvenient,  but  it  

usually  goes  away  by  itself  in  a  couple  of  days”  

Barriers  to  Using  Product:  • Need  to  give  child  too  much  fluid,  too  oren  

• Not  perceived  as  necessary  medicine  –  will  not  cure  symptoms  so  can  do  without  it  

Enablers  to  Using  Product:  • VisiAng  a  HCP  • HCP  recommendaAon  • Availability  of  product  • Compelling  price  

AspiraHons/MoHvators:  • For  child?  EducaAon?  • For  self?  

InteracHon  with  HCP’s:  • Child  has  been  immunised  by  ANM  at  6  months  and  9  months  

Media  ConsumpHon:  •  No  exposure  to  TV  •  Radio  once  per  week  •  No  print  •  Husband  sees  TV  once  

per  week  

29

Agency  to  expand  on  the  rural  mum  profile  

Introducing  our  rural  mum  

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mums  with  child  suffering  diarrhea

take  acAon  straight  away

give  fluids  at  home

visit  Doctor  if  diarrhoea  

persists/worsens

ORS  1st  line

visit  Doctor  if  diarrhoea  

persists/worsens

watch  and  wait

visit  Doctor  if  diarrhoea  

persists/worsens

“Diarrhea  is  a  bit  annoying  and  can  make  my  child  lethargic  for  a  few  days,  but  other  than  that  it  is  not  serious.  I  know  that  it  will  stop  in  3-­‐4  days”  

“I  am  happy  to  treat  at  home  for  the  first  couple  of  days  using  sugar-­‐salt-­‐lemon  or  any  other  fluid,  it  will  usually  fix  itself,  and  if  not,  I  can  easily  see  my  RMP”  

Current  Treatment  Seeking  Behavior    

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 PATH TO PURCHASE

Target  Audience    Rural  mums  with  children  under  the  age  of  5  years.    

Audience  Insight    “I  don’t  need  to  see  my  HCP.  Diarrhea  is  a  bit  annoying  and  inconvenient,  but  it  usually  goes  away  by  itself  in  a  couple  of  days”    

Growth  Priority   Convince  mums  that  “watch  &  wait”  or  give  home  fluids,  to  visit  their  doctor  straight  away  

TODAY                    

FUTURE    Behaviour  (What  are  they  buying/doing?)  Currently  doing  nothing  for  the  first  day  or  two,  then  going  to  their  local  RMP  to  request  something  to  stop  the  diarrhea.    Antude  (Why  are  they  buying/doing  it?)  “I  know  that  diarrhea  isn’t  serious,  I’ll  wait  for  a  day  or  so  to  see  if  the  diarrhea  goes  away  by  itself.  If  it  doesn’t  improve  I’ll  go  and  see  my  local  doctor  to  get  something  to  stop  the  diarrhea”    

 Behaviour  (What  will  they  buy/do?)  Go  and  see  their  doctor  on  the  first  day  that  diarrhea  starts      Antude  (Why  will  they  buy  it?)  “I  understand  that  diarrhea  is  a  serious  condiAon  that  could  harm  my  child.  I  need  to  see  my  doctor  when  the  diarrhea  starts”    

PRIMARY  BARRIER    

“Diarrhea  is  not  serious,  I  don’t  need  to  treat  it  straight  away”  

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Task  map  –  immediate  acAon    

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Insight:  •  “I  don’t  need  to  see  my  HCP.  Diarrhea  is  a  bit  annoying  and  inconvenient,  

but  it  usually  goes  away  by  itself  in  a  couple  of  days”    

Single  Minded  Benefit:  •  If  I  see  my  HCP  soon  arer  the  diarrhea  starts,  my  child  will  not  suffer  and  

will  recover  quickly  

Reason  to  Believe:  •  My  HCP  will  give  me  ORS  that  will  stop  my  child  becoming  dehydrated  •  My  HCP  will  give  me  zinc  that  will  allow  my  child  to  recover  faster    

32

Consumer  creaAve  strategy    

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   “Diarrhea  is  not  serious,  I  don’t  need  to  treat  it  straight  away”  

KEY  KNOWLEDGE  GAPS   KEY  MEASUREMENTS  OF  SUCCESS  

   At  what  point  does  a  mum  deem  diarrhea  to  be  serious  enough  to  take  the  child  to  a  HCP?      

•  Frequency  or  wateriness  of  stools?    •  VomiAng?  •  Length  of  Ame?    •  Energy  level  of  child  •  Childs  thirst  or  appeAte?  •  CombinaAon  of  the  above  •  Something  else?    

Gates  baseline  shows  that;  too  many  stools,  vomiAng  and  fever  are  the  main  reasons  to  seek  care.    

•  Visited  their  HCP  on  last  diarrhea  episode  arer  x  days  (from  x  days)  to  get  treatment  

•  Used  ORS  +  Zinc  to  treat  child  on  last  diarrhea  episode  from  x%  to  x%  

•  “I  believe  diarrhea  is  a  serious  medical  condiAon”  from  x%  to  x%  

•  “I  will  visit  my  HCP  to  get  treatment  for  diarrhea”  from  x%  to  x%  

•  “I  believe  that  ORS  +  Zinc  is  the  best  treatment  for  my  child’s  diarrhea”  from  x%  to  x%  

33

What  do  we  know?  What  does  success  look  like?  

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Defining  our  Target  Market  Who  are  the  healthcare  professionals  that  we  need  to  reach?        

 

34

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 AYUSH  25%  

CharacterisAcs  of  treatment  seeking  behavior  in  India  

Unqualified  RMPs  65%  

MBBS    Allopathic  10%  

53.69%   52.26%   53.67%  59.50%  

48.94%  

Poorest  QuinAle  

Next  20%   Next  20%   Next  20%  Least  poor  quinAle  

RMP  Treatment  Seeking    

•   RMPs  treat  more  than  50%  cases  of  common  illnesses  in  rural  areas    

Source:  Centre  for  policy  research:-­‐“Mapping  medical  providers  in  rural  India”  A  Parallel  Health  Care    market:  Rural  Medical  PracAAoners  in  West  Bengal,  India      ]  

35

Unqualified  pracAAoners    are  the  most  preferred  source  of  treatment  for  common  illnesses,  especially  in  our  target  market  

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Demographics:  •  Male  •  Age  40  •  School  unAl  16  years  old  •  Can  read  basic  Hindi  (not  English)  •  Grew  up  in  the  village  where  they  have  their  pracAce  

Key  Influencers:  •  Their  mentor  or  teacher  •  GP  prescribing  pracAces  in  

nearby  town  •  News  from  bigger  towns  •  (unlikely  to  be  influenced  by  

female  HCP’s)  

Sources  of  InformaHon:  •  Mentor  or  teacher  •  Pharmacy  in  town  where  they  purchase  

products  (visit  at  least  fortnightly)  •  Pharma  reps  •  Health  secAon  of  local  Hindi  newspaper  

Diarrhea  History:  Treat  2-­‐3  children/day  in  peak  season  (1-­‐2/week  in  dry  season)  

Key  Insights:  e.g  “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  just  some  

ORS”  

Barriers  to  RecommendaHon:  •  No  1  moAvator  is  repeat  business  –  so  want  

to  prescribe  the  best  product  •  Lack  of  belief  in  product  •  Lack  of  confidence  with  product  •  Lack  of  paAent  ability  to  pay  •  Lack  of  availability  

Enablers  to  RecommendaHon:  •  Confidence  in  product  and  repeat  business  •  High  margins  

36

Agency  to  expand  on  the  RMP  profile  

Introducing  our  RMP  

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Task  Map  –  RMP

 

PATH TO RECOMMENDATION

Target  Audience   Rural  medical  pracAAoners    

Audience  Insight    “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  just  some  ORS”    

Growth  Priority   Convince  the  RMP  to  prescribe  ORS  AND  Zinc  to  treat  diarrhea  

TODAY                    

FUTURE    Behaviour  (What  are  they  recommending?)  They  are  recommending  anAbioAcs  or  anA-­‐diarrheals  to  stop  the  diarrhea.      Antude  (Why  are  they  recommending  it?)  “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  just  some  ORS”    

 

Behaviour  (What  will  they  recommend?)  Prescribe  ORS  and  Zinc        Antude  (Why  will  they  recommend  it?)  “I  understand  that:  •  ORS  is  essen@al  to  prevent  life  threatening  

dehydra@on  •  Zinc  helps  the  child  to  recover  quickly  from  diarrhea  

and  prevents  future  episodes  •  An@bio@cs  are  not  useful  in  most  cases  of  diarrhea  •  An@-­‐diarrheals  can  be  harmful  to  the  child”  

PRIMARY  BARRIERS  TO  RECOMMENDATION    

An@bio@cs  and  an@-­‐diarrheals  are  the  best  medicine  available  to  treat  diarrhea  

KEY  KNOWLEDGE  GAPS   KEY  MEASUREMENTS  OF  SUCCESS    ?   •  “I  prescribed  ORS  +  Zinc  the  last  Ame  I  treated  a  child  for  diarrhea”  

•  “I  believe  anA-­‐diarrheals  are  not  the  best  way  to  treat  childhood  diarrhea”  •  “I  believe  anA-­‐diarrheals  can  be  harmful  to  a  child”  •  “I  believe  anAbioAcs  are  only  useful  in  diarrhea  when  there  is  clear  evidence  of  cholera  or  dysentry”  •  “I  believe  it  is  important  to  educate  mums  about  the  importance  of  keeping  their  child  hydrated  during  diarrhea”    •  “I  believe  that  ORS  is  the  best  way  to  rehydrate  a  child  during  diarrhea”  •  “I  am  aware  of  zinc  for  the  treatment  of  diarrhea”  •  “I  believe  zinc  speeds  recovery  from  diarrhea”  •  “I  believe  that  zinc  can  help  prevent  diarrhea  for  3  months”   37

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Insight:  •  “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  

just  some  ORS”  

Single  Minded  Benefit:  •  If  I  prescribe  ORS  and  Zinc  the  child  will  not  suffer  and  will  recover  quickly,  

which  means  paAents  will  return  to  me  

Reason  to  Believe:  •  ORS  stops  the  child  suffering  life  threatening  dehydraAon  •  Zinc  allows  the  child  to  recover  faster  and  prevent  re-­‐occurrence    

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HCP  CreaAve  Strategy  

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InternaAonal  UN/WHO  

Local  Government  bodies:  IMA  /  IAP  

Pediatrician  

GP  

RMP  and  Drug  Store  Owner  

Consumer  

While  RMP’s  are  our  key  focus,  it  will  be  essenAal  to  reach  their  key  influencers  

Medical  RepresentaAve   Medical  Journals  

Medical  RepresentaAve  

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Building  on  the  FHI  360    Rural  DistribuAon  Model      

OperaHonal  in  18  districts  of  Ugar  Pradesh  and  Gujarat  the  model  serves    close  to  60,000  formal/informal  providers  and  drug  stores    

60,000  providers  and  drug  stores  have  been  reached  to  promote  ORS  and  zinc  products-­‐more  than  any  big  pharmaceuHcal  company  in  the  region      

NGOs     PharmaceuAcals      

A  field  force  of  over  160  workers  promote  and  place  ORS  and  zinc  products  in  towns  that  cut  off  by  the  distribuHon  system  of  tradiHonal  pharmaceuHcal  companies    

Over  1  million  detailing  visits  have  been  completed  so  far    

Over  1  million  units  of  zinc  and  500,00  units  of  ORS  have  been  sold  already    

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AddiAonal  consideraAons      

 

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Path  to  Purchase  Possible  OpportuniAes  to  Leverage  

   Mass  &  Mid-­‐Media  BharA  Airtel  Digital  Green  Frog  Design    Lalela  Project    Live  from  Earth    Sesame  workshop  Vodafone    

   Direct  communicaHon  Center  for  Interfaith  AcAon    Girl  Scouts  IPHA  Gujarat      Rajiv  Gandhi  Mahila  Vikas    Religions  for  Peace    SEWA  Swaasthya  UNICEF  SMNet    

   Rural  Medical  PracHHoners  A  team  of  detailers  will  be  available  over  the  3  states  

ATTRACT:   INTERACT:   ACT:  

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TOWN/VILLAGE POPULATION

>5L 50K – 5L 5K – 50K 1K – 5K <1K

%  of  populaHon   14%   8%   10%   44%   24%  

Ease  of  delivery   "    High  road  

connecAvity;  channels  served  by  urban  network  

"25%    

High  road  connecAvity;  

channels  served  by  urban  network  

"    High  road  

connecAvity;  patchy  service  by  rural  

network  

"    Medium  road  

connecAvity;  few  rural  delivery  networks  exist  

"    Lixle  road  connecAvity  

Access  to  retail  channels   "      Large  number  of  

chemists  

"      Large  number  of  

chemists  

"25%      

Chemists  sAll  available  

"    Few  chemists  exist   "    

Few  chemists  exist    

Availability  of  ORS  and  zinc     "    

Average  "    

Average    "    Low  

"    Very  Low    

"    Very  Low    

Further  partnerships  needed  to  reach  rural  markets  

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AddiAonal  consideraAons  and  opportuniAes  to  explore    

•  High-­‐profile  individuals  that  can  increase  visibility  around  campaign    and  potenAally  endorse  zinc  and  ORS  (President  Clinton,  president  of  IAP,  senior  GoI  officials,  celebriAes)  

•  State  governments  and  child  health  programs  with  budgets  to  allocate  to  communicaAon  campaigns    

•  ExisAng  materials  and  resources  developed  for  similar  campaign  efforts  •  ExisAng  experAse  and  reach  of  Indian  private  sector  to  expand  campaign  

reach  and  fill  funding  gaps  

44

AddiAonal  consideraAons  and  opportuniAes  to  explore  

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Summary:      

 

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The  Key  Problem:  

•  Mums  don’t  believe  that  diarrhea  is  a  serious  illness.  They  do  not  believe  that  it  can  harm  their  child.    

•  They  watch  and  wait  for  several  days  unAl  the  condiAon  worsens,  before  they  will  go  and  visit  their  front  line  healthcare  provider  (HCP).  

•  Once  they  do  visit  their  HCP,  they  have  come  to  expect  that  they  will  be  given  medicaAon  that  will  stop  their  child’s  diarrhea  within  a  day.  

•  HCP’s  believe  that  anAbioAcs  and  anA-­‐diarrheals  are  the  best  treatment  for  diarrhea  to  saAsfy  these  paAent  expectaAons  

The  key  problem  

46  

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 PATH TO PURCHASE

Target  Audience    Rural  mums  with  children  under  the  age  of  5  years.    

Audience  Insight    “I  don’t  need  to  see  my  HCP.  Diarrhea  is  a  bit  annoying  and  inconvenient,  but  it  usually  goes  away  by  itself  in  a  couple  of  days”    

Growth  Priority   Convince  mums  that  “watch  &  wait”  or  give  home  fluids,  to  visit  their  doctor  straight  away  

TODAY                    

FUTURE    Behaviour  (What  are  they  buying/doing?)  Currently  doing  nothing  for  the  first  day  or  two,  then  going  to  their  local  RMP  to  request  something  to  stop  the  diarrhea.    Antude  (Why  are  they  buying/doing  it?)  “I  know  that  diarrhea  isn’t  serious,  I’ll  wait  for  a  day  or  so  to  see  if  the  diarrhea  goes  away  by  itself.  If  it  doesn’t  improve  I’ll  go  and  see  my  local  doctor  to  get  something  to  stop  the  diarrhea”    

 Behaviour  (What  will  they  buy/do?)  Go  and  see  their  doctor  on  the  first  day  that  diarrhea  starts      Antude  (Why  will  they  buy  it?)  “I  understand  that  diarrhea  is  a  serious  condiAon  that  could  harm  my  child.  I  need  to  see  my  doctor  when  the  diarrhea  starts”    

PRIMARY  BARRIER    

“Diarrhea  is  not  serious,  I  don’t  need  to  treat  it  straight  away”  

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Task  map  –  immediate  acAon    

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Insight:  •  “I  don’t  need  to  see  my  HCP.  Diarrhea  is  a  bit  annoying  and  inconvenient,  

but  it  usually  goes  away  by  itself  in  a  couple  of  days”    

Single  Minded  Benefit:  •  If  I  see  my  HCP  soon  arer  the  diarrhea  starts,  my  child  will  not  suffer  and  

will  recover  quickly  

Reason  to  Believe:  •  My  HCP  will  give  me  ORS  that  will  stop  my  child  becoming  dehydrated  •  My  HCP  will  give  me  zinc  that  will  allow  my  child  to  recover  faster    

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Consumer  creaAve  strategy    

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Task  Map  –  RMP

  PATH TO RECOMMENDATION

Target  Audience  Rural  medical  pracAAoners    

Audience  Insight  

 “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  just  some  ORS”    

Growth  Priority   Convince  the  RMP  to  prescribe  ORS  AND  Zinc  to  treat  diarrhea  

TODAY                    

FUTURE    Behaviour  (What  are  they  recommending?)  They  are  recommending  anAbioAcs  or  anA-­‐diarrheals  to  stop  the  diarrhea.      Antude  (Why  are  they  recommending  it?)  “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  just  some  ORS”    

 Behaviour  (What  will  they  recommend?)  Prescribe  ORS  and  Zinc        Antude  (Why  will  they  recommend  it?)  “I  understand  that:  •  ORS  is  essen@al  to  prevent  life  threatening  

dehydra@on  •  Zinc  helps  the  child  to  recover  quickly  from  

diarrhea  and  prevents  future  episodes  •  An@bio@cs  are  not  useful  in  most  cases  of  

diarrhea  •  An@-­‐diarrheals  can  be  harmful  to  the  child”  

PRIMARY  BARRIERS  TO  RECOMMENDATION    

An@bio@cs  and  an@-­‐diarrheals  are  the  best  medicine  available  to  treat  diarrhea  

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Insight:  •  “By  the  @me  they  get  to  me,  they  need  something  to  stop  the  diarrhea  not  

just  some  ORS”  

Single  Minded  Benefit:  •  If  I  prescribe  ORS  and  Zinc  the  child  will  not  suffer  and  will  recover  quickly,  

which  means  paAents  will  return  to  me  

Reason  to  Believe:  •  ORS  stops  the  child  suffering  life  threatening  dehydraAon  •  Zinc  allows  the  child  to  recover  faster  and  prevent  re-­‐occurrence    

50

HCP  CreaAve  Strategy  

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AddiAonal  consideraAons  and  opportuniAes  to  explore    

•  Can  not  refer  explicitly  to  Rural  Medical  PracAAoners  •  Can  not  feature  any  one  brand  of  product  in  communicaAons  

51

Mandatories

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QuesAons?  

Contact:  Melinda  Stanley  [email protected]  Ph:  9910  461  341      

52

QuesAons?  

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•  The  Private  Sector  Market  for  Diarrhea  Treatment  in  India  •  MART  research  •  PATH  research  

53

Appendices