incidence, predictors and outcomes of acute kidney injury following transcatheter aortic valve...

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TCT@ACC-i2: The Interventional Learning Pathway A1747 JACC April 1, 2014 Volume 63, Issue 12 INCIDENCE, PREDICTORS AND OUTCOMES OF ACUTE KIDNEY INJURY FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT Poster Contributions Hall C Saturday, March 29, 2014, 10:00 a.m.-10:45 a.m. Session Title: Valvular and Structural Heart Intervention Abstract Category: 42. TCT@ACC-i2: Aortic Valve Disease Presentation Number: 2101-302 Authors: Venkatesan Dyanesh Vidi, Zia Rab, Dan Inder Sraow, Effe A. Mihelis, S. Jacob Scheinerman, Robert Palazzo, Barry M. Kaplan, Rajiv Jauhar, Perwaiz Meraj, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY, USA Background: Acute kidney injury (AKI) after Transcatheter aortic valve replacement (TAVR) is associated with poor prognosis. However, there is limited data on the incidence and impact of AKI following TAVR defined using the VARC-2 criteria. Method: 90 consecutive TAVR procedures performed in 2 large hospitals in our health system were analyzed. AKI was defined according to the revised VARC-2 criteria based on AKIN system. Patients on hemodialysis prior to TAVR (n=5) were excluded. Incidence, predictors and outcomes following AKI were analyzed. Results: AKI occurred in 29 (32%) patients. Stage 1-AKI was seen in 25 (28%) and stage 2-AKI in 4 (4%) patients. None developed stage 3-AKI. Patients who developed AKI were more likely to be males, those who received ≥5 units of RBCs postoperatively, and those who had TAVR on an urgent basis. Thirty-day mortality, myocardial infarction, and stroke were not significantly different compared with patients who did not develop AKI. In multivariable analysis, male gender and urgent TAVR procedure were found to be significant predictors of AKI following TAVR (Table). Conclusion: In our observational registry, AKI was commonly seen. Male gender and urgent TAVR procedure were found to be significant predictors of AKI following TAVR.

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Page 1: INCIDENCE, PREDICTORS AND OUTCOMES OF ACUTE KIDNEY INJURY FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT

TCT@ACC-i2: The Interventional Learning Pathway

A1747JACC April 1, 2014

Volume 63, Issue 12

inciDence, PreDictors AnD outcoMes of Acute kiDney injury folloWing trAnscAtheter Aortic VAlVe rePlAceMent

Poster ContributionsHall CSaturday, March 29, 2014, 10:00 a.m.-10:45 a.m.

Session Title: Valvular and Structural Heart InterventionAbstract Category: 42. TCT@ACC-i2: Aortic Valve DiseasePresentation Number: 2101-302

Authors: Venkatesan Dyanesh Vidi, Zia Rab, Dan Inder Sraow, Effe A. Mihelis, S. Jacob Scheinerman, Robert Palazzo, Barry M. Kaplan, Rajiv Jauhar, Perwaiz Meraj, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY, USA

background: Acute kidney injury (AKI) after Transcatheter aortic valve replacement (TAVR) is associated with poor prognosis. However, there is limited data on the incidence and impact of AKI following TAVR defined using the VARC-2 criteria.

Method: 90 consecutive TAVR procedures performed in 2 large hospitals in our health system were analyzed. AKI was defined according to the revised VARC-2 criteria based on AKIN system. Patients on hemodialysis prior to TAVR (n=5) were excluded. Incidence, predictors and outcomes following AKI were analyzed.

results: AKI occurred in 29 (32%) patients. Stage 1-AKI was seen in 25 (28%) and stage 2-AKI in 4 (4%) patients. None developed stage 3-AKI. Patients who developed AKI were more likely to be males, those who received ≥5 units of RBCs postoperatively, and those who had TAVR on an urgent basis. Thirty-day mortality, myocardial infarction, and stroke were not significantly different compared with patients who did not develop AKI. In multivariable analysis, male gender and urgent TAVR procedure were found to be significant predictors of AKI following TAVR (Table).

conclusion: In our observational registry, AKI was commonly seen. Male gender and urgent TAVR procedure were found to be significant predictors of AKI following TAVR.