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www.england.nhs.uk Implementing National Clinical Reform: The National VTE Prevention Programme in England Roopen Arya & Helen Morrison The Quantum Leap, 9 September 2014

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Page 1: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

www.england.nhs.uk

Implementing National

Clinical Reform:

The National VTE

Prevention Programme

in England

Roopen Arya &

Helen Morrison

The Quantum Leap, 9 September 2014

Page 2: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

www.england.nhs.uk

Implementing National

Clinical Reform:

The National VTE

Prevention Programme

in England

Roopen Arya &

Helen Morrison

The Quantum Leap, 9 September 2014

Page 3: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Setting the scene – rationale for VTE prevention

Devising a VTE prevention protocol

The national VTE prevention programme

Improving outcomes

Summary

Our Presentation:

Page 4: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Venous Thromboembolism (VTE)

Deep vein thrombosis (DVT)

Pulmonary embolism (PE)

Presentation:

Acute VTE

Complications:

Post thrombotic syndrome

Pulmonary hypertension

Recurrent VTE

~10% mortality

Page 5: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Burden of VTE

Population of UK, 2011

63 MILLION

Annual national VTE rate

63,000

VTE deaths

6,300

1/1000/year

10%

Page 6: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Preventing VTE in hospitalised patients

• Hospitalised patients at high risk of VTE

• VTE leads to substantial cost, mortality and morbidity

• Effective, safe and cost-effective measures to prevent hospital-acquired VTE exist

• Prevention of VTE should be standard of care in hospitals

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Health Committee: Key themesFeb 2005

• Awareness

• National guidelines

• NICE guidelines

• Education

• Implementation

Risk assessment

Thrombosis Committees

Thrombosis Teams

Page 8: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Identify at-risk patient

Counsel at-risk patient

Prescribethromboprophylaxis

VTE Prevention Pathway

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Page 10: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Ensuring quality in VTE prevention:

NICE Quality Standard for VTE Prevention (QS3)

1 All patients, on admission, receive an assessment of VTE and

bleeding risk using the clinical risk assessment criteria described in the

national tool

2 Patients/carers are offered verbal and written information on VTE

prevention as part of the admission process.

3 Patients provided with anti-embolism stockings have them fitted and

monitored in accordance with NICE guidance.

4 Patients are re-assessed within 24 hours of admission for risk of VTE

and bleeding.

5 Patients assessed to be at risk of VTE are offered VTE prophylaxis in

accordance with NICE guidance

6 Patients/carers are offered verbal and written information on VTE

prevention as part of the discharge process.

7 Patients are offered extended (post hospital) VTE prophylaxis in

accordance with NICE guidance

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Link Nurse/

MidwivesPatient

information

Thrombosis

team

Staff

education

RCA of

HAT cases

Electronic

VTEp

systems

Audit

programme

VTE

Prevention

Supportive

managers

Preventing VTE

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Patient information

Page 14: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Electronic solutions: VTE risk assessment

Page 15: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Electronic solutions: prescribing thromboprophylaxis

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Electronic solutions: real-time monitoring

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VTE prevention: Patient-centred care

• Risk assessed for VTE

• Patient information

• Care plan

• Suitable prophylaxis

• Mobilisation and physio

• Extended prophylaxis

• Advice on discharge

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The national VTE prevention

programme

Page 19: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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2004 2005 2006 2007 2008 2009 2010 2011

Adaptive strategy and consistent pressure

ensures VTE prevention is made a clinical priority

The Journey

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Timeline

Feb 2005: Health Select Committee Inquiry leads to establishment of an independent expert working group on VTE Prevention

Apr 2007: CMO announces national approach recommending risk assessment for all patients admitted to hospital

Nov 2007: VTE Exemplar Centres launched

Sep 2008: national risk assessment tool

Jun 2009: NHS Leadership Summit

2010: Focal point for change

Beginning of implementation phase of national programme

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Introduction of system measures

21

National clinical guidelines for reducing risk in hospitalised patients

National risk assessment tool updated in line with guidance

Mandatory collection of VTE risk assessment data

Introduction of financial incentive to encourage providers to focus on VTE prevention

VTE becomes first national CQUIN goal

Strengthening of commissioning arrangements in NHS standard contract

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VTE Prevention in the NHS

Quality Framework

22

Programme transferred to NHS England in April 2013: maintained a high profile

Although it is a theme that cuts across all Domains, VTE Indicator is in Domain 5 of NHS Outcomes Framework

Priority area for improvement in Patient Safety

VTE

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Programme governance

NHS England Board

Expert Groups VTE Board Expert Groups

Patient Safety Steering Group

Page 24: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Priority work streams

Commissioning Education Outcomes

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Proportion of adult hospital admissions risked assessed for VTE

(Quarter 2 2010/11 to Quarter 2 2013/14, England)

Impact of CQUIN

Page 26: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Clear vision

26

Important to extend the reach of the programme beyond hospitals

Whole system issue

VTE prevention should be seen as part of the necessary foundations of the provision of safe, high quality, effective patient care

High quality VTE prevention should underpin the commissioning of services across whole range of specialities – medical & surgical

Education, education, education…….

Aim: to reduce avoidable death, disability and chronic ill-health

from hospital-associated VTE

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VTE Risk Assessment –

A National Quality Requirement

27

National Quality

Requirement

Threshold

(2014/15)

Method of Measurement

(2014/15)

Consequence of breach Monthly or annual

application of

consequence

Applicable

Service

Category

VTE risk assessment:

all inpatient Service

Users undergoing risk

assessment for VTE, as

defined in Contract

Technical Guidance

95% Review of monthly Service

Quality Performance

Report

Where the number of

breaches in the month

exceeds the tolerance

permitted by

the threshold, £200 in

respect of each excess

breach above that

threshold

Monthly Acute

2014/15 NHS Standard Contract Particulars, Schedule 4B (p48)

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Contract Service Conditions for VTE

28

2014/15 NHS Standard Contract Service Conditions: Records & Reporting, SC20 (p16)

SC20 Venous Thromboembolism 20.1 The Provider must: 20.1.1 comply with Guidance (including NICE Guidance) in relation to venous thromboembolism; 20.1.2 perform Root Cause Analysis of all confirmed cases of pulmonary embolism and deep vein thrombosis acquired by Service Users while in hospital (both arising during a current hospital stay and where there is a history of hospital admission within the last 3 months, but not in respect of Service Users admitted to hospital with a confirmed venous thromboembolism but no history of an admission to hospital within the previous 3 months); and 20.1.3 if required by the Co-ordinating Commissioner, perform local audits of Service Users’ risk of venous thromboembolism and of the percentage of Service Users assessed for venous thromboembolism who receive the appropriate prophylaxis, and the Provider must report the results of those Root Cause Analyses and audits to the Co -ordinating Commissioner on request. There is a specific requirement in the Reporting Requirements (Schedule 6B of the Particulars) for the provider to report “the outcome of all Root Cause Analyses and audits performed pursuant to Service Condition 20 (Venous Thromboembolism)”.

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Best Practice

29

NICE Quality Standard for VTE Prevention (QS3)

Use measures in contract service specs to set KPIs to drive up quality & improvement

Page 30: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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The National VTE Exemplar Centres network

Page 31: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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The National VTE Exemplar Centres network

Page 32: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Our website: a central resource of

information

Page 33: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Patient empowerment

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Education

Currently working with HEE on 3 more e-learning modules:

Primary care

Commissioning

Undergraduate Education

Page 35: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

Implementing change

Changing practiceChanging

systems

Changing culture

Making VTE a priority

Working to a national model

Changing the cultural landscape

Strategic leadership of change

Operational leadership of change

Changing culture for healthcare professionals

Changing culture through training

System for recording information

Managing change

Establishing an implementation

Team

Education & training to support

systems change

System feedback

New processes

Comprehensive practice guidance

Named lead

Support for changing practice

Page 36: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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The results of our programme…

Improving

Outcomes

Page 37: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Identify at-risk patient

Counsel at-risk patient

Prescribethromboprophylaxis

VTE PREVENTION PATHWAY

Hospital-associated Thrombosis

Bleeding

Process

Measures

Outcome

Measures

Page 38: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Process measures: AUDIT

Page 39: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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VTE Prevention Audit

Sept’11 Feb’12 Sept’12 Feb’13 Sept ‘13

Sample

Size

530 patients 476 patients 553 patients 452 patients 515 patients

Clinicians 27 23 35 25 25

Wards/

Units

21 20 29 25 29

CCTD 32 patients 25 patients 15 patients 15 patients 25 patients

LRS 176 patients 25 patients 211 patients 171 patients 145 patients

NS 91 patients 83 patients 130 patients 112 patients 161 patients

TEAM 201 patients 145 patients 147 patients 120 patients 138 patients

W&C 30 patients 40 patients 50 patients 34 patients 46 patients

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Findings: Standard 1

96 93 96 96 100

84

98

73

98 98 99 10099 100 99 100 98 100

0

20

40

60

80

100

KCH Critical Care LRS NS TEAM Womens

%

Sept'12 Feb-13 Sep-13

Patients risk assessed

Page 41: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Findings: Standard 4

Was pharmacological or mechanical TP correct? Sept 2013

90 88 8493 92 9694 100

8898 96

85

0

20

40

60

80

100

KCH CriticalCare

LRS NS TEAM Womens

Appropriate Chemical Appropriate Mechanical

Page 42: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Determining outcomes:Hospital episode statistics VTE rates

Page 43: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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National VTE mortality data

England

Year VTE listed as

cause of death

2007 4,827

2008 4,862

2009 4,910

2010 4,971

2011 4,557

2012 4,663

Office for National Statistics, 2012

Page 44: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Potential Lives Saved

2011 495

2012 449

Actual Mortality Rate vs

Predicted (%)

2011 90.63

2012 91.59

National VTE mortality data

England

Office for National Statistics, 2012

Catterick & Hunt 2014

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Page 46: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Patients >3 days hospital stay

0.5 1 2

Total Primary VTE related deaths 0.85 (0.75, 0.96; p=0.011: n=2213)

Total VTE related deaths 0.92 (0.85, 0.99; p=0.033: n=5985)

Primary VTE related inhospital deaths 0.86 (0.74, 1.01; p=0.061: n=1318)

VTE related inhospital deaths 0.92 (0.84, 1.00; p=0.057: n=4334)

Primary VTE Deaths at 90 days 0.81 (0.67, 0.97; p=0.026: n=895)

VTE related deaths at 90 days 0.91 (0.79, 1.05; p=0.196: n=1651)

VTE related Readmissions 1.04 (0.97, 1.11; p=0.301: n=8578)

Relative Risk (95% CI; p: n = events)

Reduction with Programme

Increase with Programme

*

*

*

Page 47: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

www.england.nhs.uk Roberts et al – Chest 2013;144:1276

Page 48: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Root cause analysis of cases of HAT

DVT/AC

clinic

Autopsies

DiagnosticsCoding

HAT

Thrombosis Team

Data collection

Notification

Learning

Trust Quality Framework

BereavementOther

hospitals

Admitting consultant

Page 49: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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• QI project at King’s College Hospital 2010-12

• Mandatory, documented VTE risk assessment,

thromboprophylaxis guidance, mandatory VTE education,

identification of hospital-acquired VTE with root cause analysis

VTE Prevention Programme Reduces

Hospital-Associated VTE

2010-11 2011-12 p

VTE risk assessment 63% (38-88) 93% (90-97)

HA-VTE 236

19.7/mo

189

15.8/mo

0.014

Inadequate prophylaxis

among HA-VTE

37% 21% 0.005

Anticoag prophylaxis in

high VTE/low bldg group

70% 89% 0.001

Roberts et al - Chest 2013;144:1276; Geerts 2014

Page 50: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Admission characteristics

Page 51: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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VTE characteristics

P=0.07

%

Fatal PE 90d mortality

% HAT presenting as PE Mortality associated with HAT

n 17 12 50 37

Page 52: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Underlying root cause

%

P=0.005 P=0.031 P=0.063

P=0.49 P=0.14

Page 53: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Mortality associated with HAT

• Most fatal PE in medical patients

• Post-op VTE: 6 deaths in 2010, 3 in 2011

• 9% medical HAT fatal, 4.7% surgical HAT

• Procedures: #NOF, abdominal hysterectomy,

Achilles tendon repair, glioma for biopsy,

Meningioma resection, prostatectomy, right

hernia repair, sleeve gastrectomy

• 90-day mortality: medical 26% vs surgical 15%

Page 54: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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When best practice fails:HAT due to thromboprophylaxis failure

• 43% HAT cases at King’s

• Medical 44%; Surgical 53%

• Median time to events 17d, so more common after

hospital discharge

• Mean number of risk factors higher

• Increased risk in subgroups of surgical patients

e.g. those with dehydration or prolonged abdominal

surgery

• In medical patients, increased age, dehydration and

cardiorespiratory disease associated with TP failure

Page 55: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Summary

VTE prevention is a top clinical priority in hospitals in England

Comprehensive VTE prevention reduces preventable patient harm

• Improving VTE prevention methods

• VTE prevention outside of acute care

• Defining outcomes

• Sustaining good practice

Challenges remain:

Page 57: Implementing National Clinical Reform - ahha.asn.au · Implementing National Clinical Reform: The National VTE ... Programme transferred to NHS England in April 2013: maintained a

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Implementing National

Clinical Reform:

The National VTE

Prevention Programme

in England

Roopen Arya &

Helen Morrison

The Quantum Leap, 9 September 2014