Impacting Our World

Innovator Hall of Fame Volume Three

As an internationally respected research institution, Purdue University is committed to doing more than innovate. We strive to create value through the commercialization of new technologies. Our defining reason to move innovations to society is to help people live longer, healthier, happier lives.

An important avenue for achieving this goal is through the research, development and commercialization of Purdue innovations – something the university already has a long, successful history in accomplishing. In fact, Purdue discoveries across many disciplines including life sciences, engineering, veterinary medicine, agriculture and computer technology are used in more than 100 countries and benefit millions of people around the world.

This booklet highlights some of the outstanding contributions Purdue innovators have made to our global society.

Dan HaslerPresident and Chief Entrepreneurial OfficerPurdue Research Foundation

Purdue Innovators Hall of Fame

www.purdue.edu

DEVELOPING NEW ENERGYSOURCES

Agrawal is a recipient of the National Medal of Technology and Innovation for his research in energy. He has 120 U.S. patents, about 500 global patents and numerous commercialization licensing agreements.

PURDUE INNOVATORRAKESH AGRAWAL

Winthrop E. Stone Distinguished Professor of Chemical EngineeringCollege of Engineering

www.purdue.edu

DEVELOPING NEW WAYS TO FREEZE-DRY

FOOD AND PHARMACEUTICALSFOR IMPROVED RESEARCH AND

DEVELOPMENT

Alexeenko’s research in nanoscale sensors promises to improve freeze-drying of pharmaceuticals and food products without using preservatives to allow the drug or food to retain its original proteins and aid in research and development. Her research also includes smallsat thrusters for spacecraft technologies.

PURDUE INNOVATORALINA ALEXEENKO

Associate Professor, School of Aeronautics and Astronautics

College of Engineering

www.purdue.edu

DETECTING FOOD-BORNE PATHOGENSBhunia helped develop a low-cost method to analyze scattered laser light to quickly identify bacteria for applications in medicine, food safety and homeland security at a much-reduced cost from conventional technologies.

PURDUE INNOVATORARUN BHUNIA

Professor of Food Science Microbiology

College of Agriculture

www.purdue.edu

CHAMPIONING SEAWATER

DESALINATIONBoudouris’ polymer research has been licensed by Anfiro to improve reverse osmosis membranes used in seawater desalination plants and applications that span across the food and beverage industry, agriculture watering, and zero emission power plant facilities.

PURDUE INNOVATORBRYAN BOUDOURIS

Assistant Professor of Chemical Engineering

College of Engineering

www.purdue.edu

DEVELOPING SMALL MOLECULESFOR HEALTH APPLICATIONSChmielewski’s research in chemical biology is helping to develop small molecules and peptides for drug discovery, bio-nanotechnology and the cellular delivery of therapeutic agents.

PURDUE INNOVATORJEAN CHMIELEWSKI

Alice Watson Kramer Distinguished Professor of Chemistry

College of Science

www.purdue.edu

HELPING WINERY OWNERS M A N A G EVINEYARDS

Ebert’s visualization and analytics research led to a startup called VinSense. The company provides wineries and wine grape growers with more accurate soil and microclimate data for improved vineyard management and harvest decisions to help growers reduce operational costs and improve crop uniformity, quantity and quality. VinSense’s software also helps producers make decisions based on real-time sensed data to improve their water management and economic and ecological sustainability.

PURDUE INNOVATORDAVID EBERT

Silicon Valley Professor of Electrical and Computer Engineering

University Faculty Scholar, College of Engineering

www.purdue.edu

IMPROVING FOOD SOURCES

FOR OUR GLOBALCOMMUNITY

Ejeta’s research led to improved sorghum varieties in his native Ethiopia and other African nations. Sorghum is a major food crop for more than 500 million people on the African continent.

PURDUE INNOVATORGEBISA EJETA

Distinguished Professor, College of Agriculture

2009 World Food Prize Laureate

FINDING NEW WAYS TO TREAT

CANCERFuchs’ research led to the development of anti-cancer chemotherapeutic drugs derived from natural sources. Akanocure Pharmaceuticals, a startup co-founded by Fuchs and Purdue alumni Sherine Abdelmawla and Mohammad Noshi, is commercializing his innovation.

PURDUE INNOVATORPHILLIP FUCHS

Professor Emeritus of Chemistry

College of Science

www.purdue.edu

www.purdue.edu

DEVELOPING NEW WAYS TO TREAT DISEASESGhosh’s multidisciplinary research projects include the areas of synthetic organic, bioorganic and medicinal chemistry. His research goals include improving treatment of HIV/AIDS, Alzheimer’s, SARS/MERS and other diseases.

PURDUE INNOVATORARUN GHOSH

Ian P. Rothwell Distinguished Professor, Organic Chemistry/Medicinal Chemistry

College of Science, College of Pharmacy

www.purdue.edu

DETECTING FOOD-BORNE PATHOGENSHirleman and his co-inventors are working on laser-based, label-free sensors to more quickly identify food-borne pathogens to help protect the world’s food supply and aid response to bioterrorism or screen for viable therapeutic stem cells.

PURDUE INNOVATOR DAN HIRLEMAN

Chief Corporate and Global Partnerships Officer Office of Research and Partnerships

www.purdue.edu

DISCOVERING ALTERNATIVE E N E R G Y SOURCES

Ho’s research in biofuels led to a strain of yeast that helps better produce ethanol from agricultural residues. In 2006, she founded Green Tech America Inc., a startup to further develop clean biofuels and green chemicals from renewable resources.

PURDUE INNOVATORNANCY HO

Emeritus Research Professor, School of Chemical Engineering

College of Engineering

www.purdue.edu

IMPROVING SYRINGE DESIGN

FOR DIABETICSHultgren’s company, Imagine Medical Device, has designed an insulin syringe that has a nearly 200 percent larger diameter than traditional syringes and a larger surface area for printing dose markers on the barrel, dramatically improving ease of use and making insulin administration safer.

PURDUE INNOVATORKYLE HULTGREN

Director

Purdue University College of Pharmacy’s Center for Medication Safety Advancement

www.purdue.edu

FINDING NEW WAYS TO TREAT DISEASEHrycyna’s molecular research goals include advancing an inexpensive and readily available antimalarial drug to treat drug-resistant malaria, and improving cancer and aging therapeutics.

PURDUE INNOVATORCHRISTINE HRYCYNA

Professor of Chemistry (Biochemistry/Chemical Biology)

College of Science

www.purdue.edu

IMPROVING SYRINGE DESIGN

FOR DIABETICSHultgren’s company, Imagine Medical Device, has designed an insulin syringe that has a nearly 200 percent larger diameter than traditional syringes and a larger surface area for printing dose markers on the barrel, dramatically improving ease of use and making insulin administration safer.

PURDUE INNOVATORKYLE HULTGREN

Director

Purdue University College of Pharmacy’s Center for Medication Safety Advancement

www.purdue.edu

DEVELOPING NEWSTRATEGIES IN

MASS SPECTROMETRYKenttämaa is working on advanced mass spectrometry, novel laser desorption techniques, gas-phase ion-molecule reactions, identification of functional groups in pharmaceuticals, and analysis of petroleum and degraded biomass.

PURDUE INNOVATORHILKKA KENTTÄMAA

Professor of Analytical Chemistry and Organic Chemistry

College of Science

www.purdue.edu

CHAMPIONING PREVENTIVEMEDICINE

Lelièvre is studying the development and behavior of both normal and cancerous cells, using a three-dimensional culture system that permits the architectural mimicry of physiologically relevant tissues.

PURDUE INNOVATORSOPHIE LELIÈVRE

Professor of Basic Medical Sciences and Cancer Pharmacology

College of Veterinary Medicine

www.purdue.edu

STUDYING TRAUMATIC

INJURYNauman’s research at the Human Injury Research and Regenerative Technologies Laboratory explores novel treatments for traumatic brain injury, spinal cord injury, musculoskeletal damage, arthritis and cancer metastasis.

PURDUE INNOVATORERIC NAUMAN

Professor of Mechanical Engineering

College of Engineering

www.purdue.edu

TRAILBLAZING FOOD

PROCESSINGNelson’s development of aseptic processing addresses post-harvest spoilage. He earned the World Food Prize in 2007 for the system that sterilizes a food product that is later packaged in a sterile container.

PURDUE INNOVATORPHILIP E. NELSON

Scholle Chair Professor in Food Processing, retired, College of Agriculture

2007 World Food Prize Laureate

www.purdue.edu

SPEEDING MASS

SPECTROMETRYANALYSIS

Ouyang’s company, PURPSEC Technologies, has designed a miniature mass spectrometry device that could improve point-of-care therapy diagnosis and compliance by reducing the time it takes to analyze samples.

PURDUE INNOVATORZHENG OUYANG

Professor

College of Engineering, College of Science

www.purdue.edu

HIGHLIGHTING TRAITS OF SOIL FUNCTION

Owens’ company, AgSoil Analytics, has developed a soil-mapping technology that provides high-precision soil information, allowing farmers to make calculated risks and evaluate the economics of their operations.

PURDUE INNOVATOR PHILLIP OWENS

Associate Professor, Department of Agronomy

College of Agriculture

www.purdue.edu

IMPROVING DRUG DELIVERYPark’s research in pharmaceutical formulations to improve drug delivery technology led to the founding of his company Akina Inc. and its PolySciTech division focusing on specialty polymers.

PURDUE INNOVATORKINAM PARK

Showalter Distinguished Professor of Biomedical Engineering, College of Engineering

Professor of Pharmaceutics, College of Pharmacy

www.purduecal.edu

ADVANCING COMPUTATIONAL

CHEMISTRYMODELING

Pelter’s research in organic chemistry and computational modeling could be used to improve research methods of ligand metal interactions and use of nanomaterials in catalysis.

PURDUE INNOVATORLIBBIE S. W. PELTER

Associate Professor of Chemistry

College of Engineering, Mathematics and Science, Purdue University Calumet

www.purdue.edu

HELPING ROBOTS “SEE” IN 3-D

LIKE HUMANSPizlo’s research in cognitive perception could address one of the biggest challenges in robotics and artificial intelligence: enabling robots to see in 3-D. He is commercializing this innovation through his startup Emulatus LLC.

PURDUE INNOVATORZYGMUNT PIZLOProfessor of Psychological Sciences

College of Health and Human Sciences

www.purdue.edu

SHEPHERDING DRUGSTHROUGH

CLINICAL TRIALSRatliff’s company, Boilermaker Health Innovations, is testing pharmaceutical compounds and bridging the gap between compound discovery and commercialization by established pharmaceutical manufacturers or startups.

PURDUE INNOVATORTIMOTHY L. RATLIFF

Robert Wallace Miller Director, Purdue University Center for Cancer Research

Distinguished Professor of Comparative Pathobiology, College of Veterinary Medicine

www.purdue.edu

IMPROVING IMPLANTABLE DEVICES AND

CELLULAR THERAPIESFOR DISEASE

Rickus’ research could improve therapies for diseases such as Type 1 diabetes, epilepsy, glioblastoma and bacterial toxins. She leads the Physiological Sensing Facility in the Bindley Bioscience Center.

PURDUE INNOVATORJENNA RICKUS

Professor of Biological EngineeringDepartment of Agricultural and Biological Engineering

Professor of Biomedical EngineeringWeldon School of Biomedical Engineering

College of Engineering, College of Agriculture

www.purdue.edu

MIMICKING TERMITES FOR FUEL PRODUCTIONEnto Bio, a company based on Scharf’s research, is developing enzymes similar to those used by termites to break down and digest wood, which could improve the process to create biofuels from wood and grass.

PURDUE INNOVATORMICHAEL SCHARF

Professor and O.W. Rollins/Orkin Chair

Department of Entomology, College of Agriculture

www.purdue.edu

IMPROVING DRUG RESEARCH

AND DEVELOPMENTTopp’s research in lyophilization has led to promising improvements in freeze-drying technology to make food, pharmaceuticals and biotech products safer and more affordable. NIST supports the Advanced Manufacturing Technology Consortia which Topp co-leads to advance freeze-drying technology.

PURDUE INNOVATORELIZABETH M. TOPP

Head, Department of Industrial and Physical Pharmacy

Dane O. Kildsig Chair in Industrial and Physical Pharmacy, College of Pharmacy

Purdue Research Foundation’s Innovator Hall of Fame recognizes

the contributions Purdue researchers and innovators have made to

positively impact our global society.

Criteria for being named to the Purdue Innovator Hall of Fame » Filed patent(s) for innovation(s) through the Office of Technology Commercialization, or

» Discovered and developed a technology that is widely used to help the global society through licensing or partnering with a company, or

» Founded or co-founded a successful company to commercialize an innovation, or

» Named a Purdue Outstanding Commercialization Award winner, or

» Recognized by federal research support agencies as a national leader in research and development, or

» Received local, state or federal funding to research and develop life-changing innovations, or

» Recognized by Purdue as a strong facilitator of entrepreneurial activities

Members for 2014

» Mahdi Abu-Omar, R. B. Wetherill Professor of Chemistry, College of Science, Professor of Chemical Engineering, College of Engineering

» Daniel G. Aliaga, Associate Professor of Computer Science, College of Science

» Alexandra Boltasseva, Associate Professor of Electrical and Computer Engineering, College of Engineering

» Charlie Bouman, Showalter Professor of Electrical and Computer Engineering and Biomedical Engineering, College of Engineering

» Gary Cheng, Associate Professor of Industrial Engineering, College of Engineering

» Ji-Xin Cheng, Professor of Biomedical Engineering, College of Engineering, Professor of Chemistry, College of Science

» Patrick Eugster, Associate Professor of Computer Science, College of Science

» Tim Fisher, James G. Dwyer Professor of Mechanical Engineering, College of Engineering

» Jay Gore, Reilly University Chair Professor of Engineering, College of Engineering

» Eckhard Groll, Reilly Professor of Mechanical Engineering, Director, Purdue Office of Professional Practice, College of Engineering

» Monika Ivantysynova, Professor of Agricultural and Biological Engineering and Mechanical Engineering, Maha Fluid Power Systems Professor, College of Engineering

» Y. Charlie Hu, Professor of Electrical and Computer Engineering, College of Engineering

» Pedro P. Irazoqui, Associate Head for Research, Weldon School of Biomedical Engineering, Showalter Faculty Scholar, Associate Professor, Weldon School of Biomedical Engineering, Associate Professor, School of Electrical and Computer Engineering, Director, Center for Implantable Devices, College of Engineering

» Gerhard Klimeck, Director of the Network for Computational Nanotechnology (nanoHUB), Reilly Director of the Center for Predictive Materials and Devices, Professor of Electrical and Computer Engineering, College of Engineering

» David Love, Professor of Electrical and Computer Engineering, College of Engineering

» David Nolte, Professor of Physics, College of Science

» Rodolfo Pinal, Associate Professor of Industrial and Physical Pharmacy, Director, Dane O. Kildsig Center for Pharmaceutical Processing Research (CPPR),College of Pharmacy

» Nainesh Rathod (1964-2014), Aeronautics and Astronautics B.A. ‘86, College of Engineering

» Vlad Shalaev, Robert and Anne Burnett Distinguished Professor of Electrical and Computer Engineering, College of Engineering

» Greg Shaver, Associate Professor of Mechanical Engineering, College of Engineering

» Riyi Shi, Professor of Neuroscience and Biomedical Engineering, College of Veterinary Medicine, College of Engineering

» Rusi Taleyarkhan, Professor of Nuclear Engineering, College of Engineering

» Bernie Tao, Professor of Agricultural and Biological Engineering and Food Science, College of Engineering

» David H. Thompson, Professor of Organic Chemistry, College of Science

» John Turek, Professor of Basic Medical Sciences, College of Veterinary Medicine

» Sherry Voytik-Harbin, Associate Professor of Biomedical Engineering, College of Engineering, Associate Professor of Basic Medical Sciences, College of Veterinary Medicine

» Matthew Ward, Research Scientist, Weldon School of Biomedical Engineering, College of Engineering

» Jason Weiss, Former Jack and Kay Hockema Professor of Civil Engineering, Director of the Pankow Materials Laboratory, College of Engineering

» Babak Ziaie, Professor of Electrical and Computer Engineering, Director of the Ziaie Biomedical Microdevices Laboratory, College of Engineering

Members for 2013

» Mikail Atallah, Distinguished Professor of Computer Science, College of Science

» Lonnie D. Bentley, Professor of Computer and Information Technology, Purdue Polytechnic Institute

» Sally Byrn, Co-founder of SSCI and Improved Pharma, leader, Greater Lafayette community

» Stephen R. Byrn, Charles B. Jordan Professor of Medicinal Chemistry, College of Pharmacy

» Paroon Chadha, Co-founder and CEO of Passageways

» Sean Connell, Chief Operating Officer, Medtric

» R. Graham Cooks, Henry B. Hass Distinguished Professor of Analytical Chemistry, College of Science

» Brad Duerstock, Associate Professor of Engineering Practice, College of Engineering

» Suresh V. Garimella, R. Eugene and Susie E. Goodson Distinguished Professor of Mechanical Engineering, Executive Vice President for Research and Partnerships

» Leslie Geddes (1921-2009), Showalter Distinguished Professor Emeritus of Biomedical Engineering, College of Engineering

» Jessica Huber, Professor of Speech, Language and Hearing Sciences, College of Health and Human Sciences

» Pete Kissinger, Professor of Analytical Chemistry, College of Science

» Paul C. Krause, Professor of Electrical and Computer Engineering, College of Engineering

» Michael R. Ladisch, Distinguished Professor of Agricultural and Biological Engineering, College of Agriculture

» Jianming Li, Chief Scientific Officer, Medtric

» Philip S. Low, Ralph C. Corley Distinguished Professor of Biochemistry, College of Science, Director, Purdue Center for Drug Discovery

» Kyle Lutes, Former Associate Professor, Department of Computer and Information Technology, Purdue Polytechnic Institute

» James Mann, Research Engineer in Industrial Engineering, College of Engineering

» Issam Mudawar, Professor of Mechanical Engineering, College of Engineering

» Alyssa Panitch, Leslie A. Geddes Professor of Biomedical Engineering, College of Engineering

» Johnny Park, Research Assistant Professor in Electrical and Computer Engineering, College of Engineering

» Joseph Pekny, Professor of Chemical Engineering, College of Engineering

» Karthik Ramani, Donald W. Feddersen Professor of Mechanical Engineering, College of Engineering

» Fred Regnier, John H. Law Distinguished Professor of Analytical Chemistry, College of Science

» J. Paul Robinson, SVM Professor of Cytomics, College of Veterinary Medicine

» W. Andy Tao, Professor of Analytical Chemistry and Chemical Biology, College of Science / College of Agriculture

» Oliver Wendt, Assistant Professor of Speech, Language and Hearing Sciences, College of Health and Human Sciences

» Mary Jean Wirth, W. Brooks Fortune Distinguished Professor of Analytical Chemistry, College of Science

» George Wodicka, Professor and Founding Head of the Weldon School of Biomedical Engineering, College of Engineering

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• www.prf.org/• www.otc-prf.org/• www.purduefoundry.com/• www.innovation-entrepreneurship-purdue.com/• www.purdueresearchpark.com

A publication of Purdue Research Foundation