immune risk phenotype dr. gabriele rumi. effect of the genetic background and aging on the immune...
TRANSCRIPT
Immune Risk Phenotype
Dr. Gabriele Rumi
Effect of the genetic background and aging on the immune system
Interplay between the IRP, low grade inflammation, and cognitive impairment in mortality
From the clinical perspective, the percentage of the cytotoxic CD8+ CD28– T cells reflected a more severe course of disease, as it correlated with distinct movement restrictions, as well as the metrology score summarizing cervical rotation (in sitting position), chin-to-jugulum distance, thoracic Schober, chest expansion, and fingers-to-floor distance (P = 0.032).
Schirmer M, Goldberger C, Würzner R, Duftner C, Pfeiffer KP, Clausen J,Neumayr G, Falkenbach A. Arthritis Res. 2002;4(1):71-6. Epub 2001 Oct 16. PubMed
Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis.
Immunological biomarkers of ageing in man changes in both innate and adaptive immunity are associated with health and longevity