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POSITIONS WANTED

Bioemist, Ph.D. (1978). Extensive teaching experi-

ence to medical and graduate students. Principle invcsti-gator of a study on sicle cell ancmia, and r elateddisorders in non American population. Currently princ-ple investigator in a study designed to evaluate a newlydeveloped antisickling a8ent. Good publications. Strongcollaborative ties with nmternational academic and re-search instiutes. Seeks academic or clinical researchposition. Box 153, SCIENCE.

Protcin Biochemist, Molecular Biologist, Ph.D. Ex-tmsivc exnece in protein purification, antibody pro-

ddon. microbial physiology, anaerobictehniques, tissue culture, nudeic acid extacions, plas-

mid preparaons, northern, western blot and muchmorc. Seeing position in industry/academia. Box 155,SCIENCE.

POSITIONS WANTED

Immunodhemiat, Ph.D. with a proven record in immu-noassay development and protein purification. Currentlyemployed at a reputable international rmsearch organiza-tion. Sceking a challenng posiion in rsar anddevclopmcnt. Box 147.

Microbial Phyiologi. To receive January Ph.D. fromCornel University. Experience in small-scale fermenta-tion, HPLC, gel filtration, affinit chromatography,measurement of intracellular merabolites. Seeking entry-level research position in publidprivate sector. Box 158,SCIENCE.

Toxicokgist, Consulting: Board certified Toxicologist;

Ph.D. biochemistry; R&D, product evaluation, litera-ture analysis, health hazard and risk assessment, occupa-tional and eavironmental regulations, sacenc/lkl inter-face. Excellent acredentials and conmunication skills. Box157, SCIENCE.

POSITIONS OPEN

ANIMAL VIROLOGIST-The Department ofVct-Sdences, University of Wyoming, has a 12-

month tenuretrackc position at the aistant or associateproessor levd in vetrinary virology. D.V.M./Ph.D. orPh.D. rquired. Dutics include approximatly 60% com-mintmcnt to conduct diagnostics within the WyomingState Vcterinary Laboratory; approximatly 20% com-

mitment to teach and 20% commitment to research.Tochnical support and competitivc salary are available.Scnd a current curriculum vitae and three keers ofreference to: Dr. Ken Mills, Dqrtment ofVetrinsa

ciences, 1190 Jackon, Larame, WY 82070. Appli-cations accpted through 1 January 1989. Wyoming is anEqual Employment Opportunity Employer.

ASSISrANT PROFESSORAL D. ANDERSON CANCER CENTER

A position is available immediately to join a laboratoryinvesigating immunotoxins directed to human tumors.Applicants should have a recent Ph.D. in molecularbiology with a strong background in recombinant DNAtechnology. Experience in immunoglobulin gene molec-ular biology is preed. Projects will focus on develop-ment of recombinant antibodies and immunotoxins.Send curriculum vitae, thesis abstract, and names andaddresses of three refereces to: Dr. Jack A. Roth, M.

D. Aaderson Hospital andTumor Intitute, Box 109,1515 Hlmb Boukvard, Houston, TX 77030. AnEqual Opporunity/Afirnative Action Employer.

Applications are invited for a position at the ASSIST-ANTPROFESSOR level in the Department of Radia-tion Oncology of McGill University. The appointeewould join a small research group working in tumorbiokogy and expeinmntal therapeutics and the position

could be of interest to radiobilogists, tamor or ccllbiologists. The applicants should have a Ph.D./M.D. and2 to 3 years of rceevant experience.

In accordance with Canadian Immigration requirements thisnotice is directed initially to Canadian dtizens and permanentresidents. Please send curricuhm vitae and names of threereferees to: Dr. Shirley Lehnert, Radiation Oncolg,Montreal Genl Hospital, 1650 Cedar Avenue,Montreal, Quebec H3G 1A4, Caada.

The Univcrsity of California, San Diego, ASSIST-ANT PROFESSOR, BIOCHEMISTRY. The Chem-istry Departrmet expects to have a position for a tenure-track opening for an outstanding candidate in the bio-chemistry area. Candidate must have a Ph.D. and ademonstrated ability for creative research and teaching atthe undergraduate and graduate lcvls. Duties wouldinclude teaching in the Cell-Biology and BiochemistryCourse in the Medical School. All applications received

through 1 December 1988 will given thoroughconsideration. Salary wicomnsurate wth experience andbased on the University of California pay scale. Candi-dates should send curriculum vitae, a list ofpublications,reprints of representative papers, a summary of research

plans and names and addresses of three rerences to:an, Bio emi Sech Committ Dert-

ment of Chemity B-32, Universiy of Caifrnia,

San Digo, La Jolla, CA 92093-0332.

The University of Califomia is an Equal OpportniutylAfirmative Action Employer.

ASSISTANT PROFESSOR-Tenure-track in ana-lytical or inorganic chemistry startng August, 1989.Must possess doctorate; subsequent postdoctoral experi-ence isp d Must establish a vigorous program ofresearch. Commitment to excellence in undergraduateand graduate teaching essential. Send application, includ-ing a complete rsum4, a description of research plans,and thre ls of recommendation, by 14 November1988 to: Professor T. Adrian George, Depanentof

C ,Uni Z ofNe:brasa-Lno,LnonNE858-0' 4.PTdqhmce: 402-472-3513. Afir-

matve Acion/Equal Opportunity Employer.

ASSISTANT PROFESSORThe Department of Chemistry, Philadelphia College

of Pharmacy and Science, invites applications for a full-time, tenure-track faculty position at the assistant profes-sor level, starting August 1989. We seek a candidate whowill establish a vigorous, productive research proramand who will excel at teaching in both our undergraduateand graduate programs. Applicants in the areas of bio-chemistry or molecular biology are preferrd, althoughexceptional candidates from other areas ofchemistry wlllalso be considered.The Philadephia College of Pharmacy and Science is

an independent, co-educational institution with 1,500undergraduate scicnce majors in eight disci lines, 120full-time faculty, and 60 graduate students. 1e Depart-ment of Chemistry has 14 faculty members and offersACS approved undergraduate degrees in chemistry andbiochemistry. Graduatc programs lead to the M.S. andPh.D. degrees in medicinal chemistry and pharmacogno-sy, and may involve imterdisciplinary research with theDcparmients of Biology, Pharmacology and Toxicology,a Pharmaceutics.

Applications should consist ofcurriculum vitae, a briefstatement of taching expenence and interests, and adesciptaon of h projects that would be pursued, aswell as start-up requirements. Applicants should alsoarnge to have undergraduate and graduate transcipts,and e letters ofrecommendation, sent by 15 Novem-ber 1988 to:

Dr. Peter CampbellChair, Faculy Search Committee

Philadelphia College ofPham and ScienceWoodland Avenue at 43r Street

Philade a, PA 19104Tlephone: 215-596-8839

Equal Opportnity/AJirnative Action Employer

The Department of Microbiology at The Ohio Statehas a tenure-track vacancy to be filled by

Au ni989 at te ASSISTANT PROPESSORIeve.Applicants must have a Ph.D., postdoctoral esearchexperience and demonstrated ch productvity inmolecular or celhlular munology Candidates with re-search interests in an infectious isease system are partic-ularly encouraged to apply. Participation in the Depart-ment's instuction of undergraduate and graduate stu-dents is expected. Excllnt laboratory space and Depart-mental support are available to cstablish mdependent andinteractive msearch programs. Candidates should submitcurriculum vitae, a summary ofresearch plans and namesof three referees by 15 December 1988 to: Dr. John N.Reeve, Chairpon, Departnt of Microbiology,484 West 12k Aveue, Columbsu, OH 43210. TheOhio State University is an AJfirmative Action/Equal Opportu-nity Emnployer and spedfically invites and encourages minorityand women applicants.

ASSISTANT PROFESSORNEUROBIOLOGYDUKE UNIVERSITY

Applications are invited for a tenure-track position inthe Department of Zoology at Duke University. We areespc interested in candidate with postoralexrience and high research promise in neurobiology,partcularly in the celular, mollar, and/or developmental areas. In addition to maintuining a vigorousrsearch program responsibilities will includching atthe graduate and under uate levels. Send curriculumvita;, description of rach interest, plus the namesand addressesof three references by 30 November 1988to: airman, Neurobiology Search Commite, De-partent ofZoology, Duke University, Durham,NC27706.kDuke University is an Equal Opportunity/AjinnativeAction Employer. Women and members ofminority groups areencouraged to apply.

PERSONNEL PLACEMENT 313

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only wth the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence. SCIENCE reserves the right, in its discretion, todecline to publish advertisements submitted to it.

LINE CLASSIFIED ADVERTISING DEADUNES:Thursday, 10 a.m., 2 weeks prior to issue date (mailedon issue date). For deadlines for display advertising,please contact Scherago Associates.

POSITIONS WANTED: 400 per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASIFIED (POSIMONS OPEN, COURSES,FELLOWSIPS, MARKETPLACE, an so forth):$38.00 per line; $380 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad cost:Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading, and/or extra line spaces, and allpartial lines (including centered reply information) arecounted as full lines. Ad titles iocated within the textare printed in boldface caps and are only 32 charac-ters per line. In ESTIMATING the cost, multiply totallines x $38.00 = approximate cost of ad. (This Is anapproximate cost ONLY: Allow for variation betweenestimated lines and actual typeset lines and the result-ing final cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

CANCELLATION POLICY:NOTE: Ad cancellations made after Thursday, TWOweeks prior to issue date incur a 10% productioncharge. Final deadline for cancellations is 12 p.m.Tuesday, ONE week prior to issue date. Cancellationsmust be in writing.

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14 OCrY)BER 1988

POSITIONS OPEN

POSITIONS OPEN

ASSISTANT PROFESSOR INCRANIOFACIAL DEVELOPMENT

The Department of Plastic Surgery and Division ofCraniofacial Surgery at the University of Virginia inCharlottesville, Virginia, is seeking an individual withexperience and training in craniofacial skeletal develop-ment. Optimaily, the individual will have had experiencein research related to cell biology, collapen chemistry orglycosaminoglycan research. The opemng for this aca-demic position is 1 January 1989. Salary is negotiabledepending upon the experience and qalifications of theindividual. The qualified individual will have postdoctor-al research experience and have the ability to conductindependent research. The research effort in craniofacialbiology at the University ofVirgjinia is expected to be anexpanding effort involving multiple disciplines over thecourse of the next 5 to 10 years. It is expected that theindividual will be capable of coordinating a full range ofresarch activities, and collaborate with individuals al-ready present in the Universit community.

Applications should be received by 15 December1988. Please send curriculum vitae, repnnts of previouspublications, plus the names, addresses, and tdelphonenumbers of three references to:

Dr. John A. PersiDivision of Craniofacial SurgeryDepartment of Plastic Surgery

Box 376University of VirgniaHealth Sciences Center

Charlottesviile, VA 22908The University of Virginia is an Equl Opportunity Employer.

THE SALK INSTITUTASSISTANT PROFESSOR

MOLECULAR NEUROSCIENCEThe Salk Institute for Biological Studies invites appli-

cations for a new junior faculty appointment in theMolecular Neurobiology Laboratory (MNL). We soekcandidates with research interests and experience in theapplication of molecular gncs to the study of thenervous system, and are particularly interested m candi-dates addressing questions related to neural develop-ment. Current areas of research in MNL indude thiestudy of neurotransamitter receptor gencs (S. Hene-mann), neural development in Drosophila (J. Thoms),neural induction in Xenopus (C. Kintner), and myclina-tion (G. Lemke). The Salk Institute offers a hiplyinteractive environment, with a number of rsagroups working in areas of molecular biology and theneurosciences. Int ed individuals should submit cur-riculum vitae, a brief statement of present and futurercsearch intcrests, and the names of three references to:

Molecular Neuroscieace Search CommitteeThe Salk InstituteP.O. Box 85800

San Diego, CA 92138The Salk Institute is an Equal Opportunity Employer,

M/F/H/V.

DEPARTMENT OF PSYCHOLOGYCORNELL UNIVERSITYPOSMON IN COGNMIIONAND/OR PERCEPTION

The Department of Psychology at Comell Universityis considering candidates for a tenure-track ASSIST-ANT PROFESSORSHIP in cognition aix/or percep-tion. Areas ofspecialization are completely open as are allperspectives (induding computational, cross-cultural, de-velopmental and mathematical). ExceptionaUy well-qual-ified individuals may apply at the associate or full profes-sor level, although an appointment at such a rank has notyet been authorized. Dossier indcuding curriculum vitae,sample reprints, and pre ts, and at least three letters ofrecommendation should be sent to:

Cognition/Pe Search Committeec/o Elke Schofield

Department of Psychology223 Uris Ri-l

Corneil Un rsityIthaca, NY 14853-7601

Review of applications will begin 15 November 1988and will continue until an appomtment has been made.Comell University is an Equal Opportunity/Affirmative ActionEmployer.

34

TWO POSMONS IN PSYCHOLOGY: TheDuke University Department of Psycholgy announcestwo openings at the ASSISTANT PROFESSOR (ten-ure-track) level to begin fall 1989. Interest in undergrad-uate and graduate teaching is important. Salaries areneoabk. Quantitative methods: A person broadlytrained in cxperimental methodology and quantitativemethods. Arca of quantitativc cmphasis is open. Anactive and excellent empirical rescarch program is expect-ed; the preferred areas of interest indlue personality/social, ncuroscicnce, and cognition. Develomental: Aperson broadly trained in developmental psychology to

b l1989. Prferenc will b given to individualswhose rerch interests pertain to problems in humancognitive development in areas such as perception, lan-guage and conmunication, infunnation processing, ctc.,and the neural organizations supporting such processes.Application matcrials, which should include curriculumvitae and at Icast three ktters ofrecommcndation, shouldbc directed to: Robert C. Carson, Chair, Personnelommittee, Department of Psychology, Duke Uni-

versity, Durm, NC 27706. Duke University is anAfirmative Action/Equal Opportunity Employer.

ASSISTANT PROFESSOR.MOLECULAR BIOLOGY

The Department of Biochemistry and the Institute ofHuman Genetics at the University ofMinnesota MedicalSchool invite aplications for a tenure-track position atthe assistant level. Preference will be given toindividuals who have had at least 2 years of postdoctoralexperience with a strong background in eukayotic mo-lecular genetics, who show promise of developing avigorous research progrm, and whose rcsearch interestscomplement those ofthe current faculty. A plicants mustbe qualified to teach in the Fraduatc and profcssionalschool courses ofered by the Dpartment and Institute.Applications must be postmark no later than 31December 1988. Send curriculum vitae, a concise planfor future research, and names of three references to:Scarch Comittee, D rtnt of Bio istyMedical School, 4-225 Mlard Hall, Uni of

Mipolis,MN 55455. The University ofMinnesota is an Equal Opportunity Educator and Employer,and specifically invites and encourages applicationsfrom womenand minorities.

ASSISTANT PROFESSORPHARMACOLOGY.The Division invites applications for a tenure-track posi-tion at the assistant profssor level with a primaryappoinrment inth School of Pharmacy. Must have aPhD. degree and postdoctoral xperience in pharmacol-ogy or toxicology and be a U.S. citizen or have the legalright to work in this country. Will be expected to assumean active teaching role and cstablish an extramurallyfunded research program. Send r6sum6, statemcnt ofrmsearch interests, and names of threc references to:Robert C. Lanman, Ph.D., Chairman, Division ofPh cology, University of Missouri-Kansas Citv2411 Holmes Street, Kansas City, MO 64108. neUniversity ofMissouri is an Equal Opportuity Employer.

ASSISTANT/ASSOCIATE PROFESSORENVIRONMENTAL TOXICOLOGY

The Department of Environmental Healti Sciences,School of Public Health and Tropical Medicne, TulaneUniversity, invites applications fur a tenure-track facultyposition at a leve based on professional experience. Theapplicant should be trained in environmental toxicologywith a Ph.D. or an equivalent degree. It is desirable thatthe applicant have experience in toxicology, environmen-tal health and environmental risk assessment and havc theability to deveop a research progam in aquatic toxicolo-gy. Those interested should send curriculum vitae andhree reerences by 30 November 1988 to:

Dr. A. J. Engande, Jr., ChairmanTulane University

Department of Environmental Health Sciencecs1430 Tulane Avenuc

New Orleans, LA 70112Tulane University is an Equal

Opportunity/Afirmative Action Employer

DEPARTMENT OF PHYSIOLOGYAND BIOPHYSICS

UNIVERSITY OF ILLINOISAT URBANA-CHAMPAIGNASSISTANT PROFESSOR

PROTEIN CRYSTALLOGRAPHYApplications are invited for a tenure-track position in

protem crystallography at the assistant proessor levelstarting Aug 1989. Applicants are required to have adoctral degree and postoctoral expenence. The suc-cessful candidate is expected to develop a vigorousindependent research progam and participate m ourundergraduate and graduate teaching programs. He/shewill join a strong group of molecular biophysicistsincluding tvo difiactonists as part of the commitmentto establish an outstanding program in suctural biolo-gy. Starting salary will bc m the range of $33,000 to$636,000, depending on experience. An additional 2-month summer salary may be gencrated from teaching orresearch sources. In order to ensure full consideration,applications must be received by 15 November 1988.Interviews may be conducted bcfore 15 November 1988,but all applications roceived by that date will receive fullconsideration. Applicants should submit curriculum vi-tae, a list of publications, a short statement of futurcresearch plans, and the names of at least three referencesto: Dr. Andrew H.-J. Wang, Chairman, Search Com-mittee, Departnt of Pysiol and Biophysics,524 Br Hail, The University of Illinois at Ur-banaCham 407 South Goodwin Avenuc, Ur-bana, IL 61801. Telcphone: 217-244-6637. The Uni-versity of ilinois is an Affirmative Action/Equal OpportunityEmployer.

ASSISTANT PROFESSOR POSMONSDUKE UNIVERSITY MEDICAL CENTER

SECTION OF CELL GROWIH,REGULATION, AND ONCOGENESIS

DUKE COMPREHENSIVECANCER CENTER

Dukc University Comprehensive Cancer Center in-vites applications for tenure-track positions in a newSection ofCcll Growth, Regulation, and Oncogenesis atthe kvel of assistant professor. Investigators working atthe molecular levcl m any area of cancer biology areCncouraged to apply, but special consideration will begiven to those working in the areas of growth anddifferentiation factors, signal transduction, molecular ba-sis ofoncogene action induding recessive oncogenes andmultiple drug resistance. Applicants with postdoctoralexperienc should have demonstrated high potential forimaginative substantial indepcndent research. Successfulcandidates will also be appointed into a basic sciencedepartment within the Medical Center.

Applicants should send curriculum vitae, and a briefdesciption of present and .proposed research to: Dr.RobertM. Bell, Head, Section ofCell Growth, Regu-lhtion andOncenes, Duke Comprehensive CanerCenter, Box 3814, Durham, NC 27710. Applicantsshould arrange for three or more letters ofrecommenda-tions to be forwarded to the same address.To be assured offill consideration, application should

be received by 5 December 1988.Duke University is an Equal Opportnity/Afirmative Ac-

tion Employer.

ASSISTANT/ASSOCIATE/FULL PROFESSOR

Applications are invited for a tenure-track position inthe Department ofAnatomy of the University of SouthCarolina School ofMedicine available 1 June 1989. Thearea of research interest is open but pference wilI begiven to individuals who are funded and have a strongbackgound in biochemistry, cell biology, and/or molec-ular biobgy. Candidates with rscarch mteres in devel-opmental biology, cardiovascular cell biology and/or theneuroscences are encouraged to apply. The successfiucandidate will be expected to partiapate in teaching oneof the fullowing courses: embryology, gross anatomy,microanatomy or ne atomy. licants should sendcurriculum vitae and te names of three references to:Dr. Louis Teracio, Department ofAnatomy, Univer-sity of South Carolina, School of Medicne, Colum-bia, SC 29208. An Equal Opporunity M/F AffirmativeAcion Employer.

SCIENCE, VOL. 242

POSITIONS OPEN POSITIONS OPEN

POSITIONS OPEN

ASSOCIATE FOR ENVIRONMENTAL QUALI-TY souht byThe Conservation Fouipdation, environmen-tat policy researh oraniation, towork pimanriy onSuperfimd Project. Assocat will draft isse papes andbackground materials and partiacpate in planing andimplementation of research cefbrt. Extensive interactionrequired with representatives of industy, gvemnt, andenvironmental area. Advanced degree in public or cnviron-mental policy or related area and 3 years of environmntalexperincne required. Superfind policy and implementationbackground pre L Sen dsu to:

M. J. JamarThe Conservation Foundation

1250 24th Street, N.W.Washington, D.C. 20037

AVIAN/WATERFOWL ECOLOGIST. A rcsearchscientist position with the USDA Forest Service, PacificNorthwest Research Station's Forestry Sciences Labora-tory in Juneau, Alaska. May be filled on either a perma-nent basis, or as a 2-year postdoctoral research appoint-ment. The incumbent will develop and conduct anindependent research program with cmphasis on func-tional processes between birds and their nipanan andwetlnd habitats in southeastern Alaska and Prince Wil-liam Sound, induding the Copper River Delta.

Applicants must hold a Ph.D. in ecology, wildlifebiology, or a related field. A strong background in avianbiology and habitat ecology is required. Experience withwaterfowl and wetLands is desired but not necessary.Preference will be given to applicants with a demonstrat-ed ability to publish scientific literature. We are an EqualOpportunity Employer and encourage women and minorities toapply.

Salary: GS-12 or 13 (about $41,500 to $55,000including 25% tax-free cost-of-living allowance) depend-ing on qfications.Send current r6sum, transcripts of college work,

names of three references, and one copy of recentpublications to: Dr. omas A. Hanley, USDA, For-estry Sciees Laboratoy, P.O. Box 20909, Juneau,AK 99802-0909. Deadline: 30 November 1988.

BIOCHEMIST. Lewis & Clark College, VisitingAssistant Professor, winter term, 1989 (3 January to 17March) seeking applications to teach undergraduate bio-chemistry (lecture and laboratory) for 10 weeks. A Ph.D.or all but dissertation in biochemisty is required. Sendletter of application, r6sumi, transcripts, as well as twoletters of recommendation by 31 October 1988 to: Dr.C. R Keedy, Chair, Chemistry Department, Lewis &Clark College, Portland, OR 97219.

THE UNIVERSITY OF CALGARYCAMPBELL MCLAURIN FOUNDATIONCHAIR IN HEARING DEFICIENCIES

The University of Calgary invites applications for thenewly endowed Chair for Hearng Deficiencies. TheChairholder will hold a full-time appointment in theappropriate department of the Facuty of Medicine atThe UJniversity of Calgary, and may be a clinical and/orbasic scientist.The incumbent ofthe Chair must have a Ph.D., M.D.,

or equivalent degree, and will be an expert and specialistin hearing deficiencies and will have a distinguishedinternational reputation in research and proven leader-ship in education.The Chairholder's responsibilities will incude Provid-

ing leadership in basic and/or clinical research in hearingdeficiencies, developing an independent world-class re-search program onented towards hearing deficiencies,promoting collaborative research across disciplines, pro-moting service and educational programmes fostering abench-to-bedside approach to research in hearing defi-ciencies, and attracting to the University outstandingstudents, research associates and faculty.

In accordance with Canadian immigration requirements, prior-ity will be given to Canada citizens and permanent residents ofCanada.

Applicants are requested to submit curriculum vitae, astatement of research interests and academic goals, andnames of three references by 1988 to:

Dr. M. Watanabe, DeanFaculty ofMedicine

The University of Calgary3330 Hospital Drivc N.w.Calgary, Aberta T2N 4N1

I4. OCTOBER I988

BIOLOGY-MOLECULAR BIOLOGY. A ten-ure-track position at ASSISTANT OR ASSOCIATEPROFESSOR rank is available at Delaware State Col-lege in January 1989. Minimum qualifications include aPh.D. in molecular biology or related field, and demon-strated ability to work effectively with students. Thesuccessful candidate will be expected to develop a re-search program and teach graduate courses in area ofexpertse. Involvement in undegraduate program mayinclude teaching introductory and/or advanced levelcourses. Experience supervising masters level studentsand publication record desirable. Send curriculum vitae,official transcipts, and three letters of reference by 28October 1988 to: Dr. Dorene Petrosky, Caisonof Biological Sciences, Delaware State Colege, Do-ver, DE 19901. Affirmative Action/Equal OpportunityEmployer.

CEILULAR/MOLECULAR PHYSIOLOGY FAC-ULTY POSMTION. A tenure-track position in theBiology Deparunent is available for August, 1989. Theposition is at the assistant professor level although moreexperienced outstanding candidates will be considered.The successful candidate will be expected to develop aproductive, extramurally funded research program; andaltemately teach an undergraduate physiology course anda specialty graduate class. All research areas to be consid-ered, although candidates who complement existingstrengths in endocrinology, muscle physiology and neu-roscience are especially encouraged to apply. Send com-plete vitac, statement of research, and names of at leastthree refirences by 15 Dcember 1988 to: Dr. PeterAbramoff, Biology Department, Marquette Universi-ty, Milwaukee, WI 53233. Equal Employment Opportuni-ty/Afirmative Action Employer.

CHAIR-DEPARTMENT OF BIOLOGYThe University of Nevada-Reno solicits applications

and nominations for the position ofchair of the Depart-ment ofBiology. A doctorate in the biological sciences isrequired. The successful candidate will have a nationallyrecognized reputation with an excellent record of re-search and extramural funding, a demonstrated commit-ment to undergraduate and graduate education, andevidence of outstanding leadership and administrativeabilities. Experience in collaborating with individualsoutside of the candidate's area of specialty is desirable.Send a letter of interest, a current curriculum vitae, astatement of administrative philosophy, and the names,addresses, and telephone numbers of five rcferences by16 November 1988, to: Biology Search Committee,c/o Barb Glazner, College of Airts and Scicnce, Uni-versity ofNcvada-Reno, Reno,NV 89557. UNR is anAffimative Action/Equal Opportunity Institution and employsonly U.S. ditizens and aliens lawfully authorized to work in theUnited States.

CHAILPERSON,DEPARTMENT OF BIOLOGY

The University of Missouri-St. Louis invites applica-tions and nominations for Chanierson of the Depart-ment of Biology. Applicants shoud have a Ph.D. in theBiologcal Sciences and research interests in an area ofecology, evolution, or systematics. Selection criteria in-lude achievements in research commensurate with ap-pointment at the rank of full professor, proven adminis-trative and leadership skills, and a concem for qualityundergraduate and graduate education. The Departmentof Biology, with 20 fll-time and 15 adjunct faculty, isundergomg a phase of vigorous growth which indudesexpansion of cilities with a new science building andincreased funding for the graduate proam. A recentlyapproved Ph.D. program with emphasLs in cvolutionarybiology, systematics, and tropical ecology wiUl be offcredin coniunction with the Missouri Botanical Garden. Thenew chair thould havc experience appropriate for imple-mentation of the Ph.D. program and a commitment tothe continued growth and development of the entirebiology department. Salary is open and competitive.Expected starting date is July 1989.We invite interested individuals to send a letter of

application, curriculum vitae, statement of rescarch, andnames, addresses, and telephone numbers of five refer-ences to: Dr. Victoria Sork, Search Committee Chair-person, Department of Biology, Universitof Mis-souri-Ste Louis, 8001 Natura[ABridge Road, St ouis, MO 63121-4499. Deadline: 30 November 1988.

The University ofMissouri-St. Louis is an Equal Opportu-nity/Affirmative Action Employer.

CELL BIOLOGISTThe Biology Department seeks a cell biologist working

on structural aspects of cell function at the molecularlevel. This is a tenure-track position at the assistantprofessor level that has been madc possible by an awardfrom the Howard Hughes Medical Institute. Candidatesare expected to develop an active research program thatcould attract external support, to play a leadership rokc inour Ph.D. program, to participate in an upper levelinterdepartmental laboratory course in structural biologyand to teach in cell biology at the undergraduate leveL.Candidates must have postdoctoral experence. This po-sition will be available for September 1989. Applicationsshould indude curriculum vitae, a statement of futurersearch plans, and three letters of reference. Send appli-cations, by 1 December 1988, to, Ccll Biologist SearchCommittee, Bioloy Department, Wcsl¢yan Univer-sity, Middletown, CT 06457-6032.

Wesleyan University is an Affirmative Action, Equal Oppor-tunity Employer. We encourage applications from minoritycandidates and women.

CHAIRPERSON, DEPARTMENT OF PLANTBIOLOGY. New department to be formed inJuly 1989from merger of botany, plant pathology, horticulture,and agronomy. Seek candidates presentiy at associate orfull professor rankwith earned doctorate in plant biologyand productive research record. Experiencc in academicadministration within the Land Grant System prefcrred.Salary and rank commensurate with experience. To apply, send curriculum vitae (non-citiiens must indudecurrcnt visa status), threc lettcrs of reference (havc sentdirectly), list of publications, and statement of academicand administrativ hilosoph by 15 Novemnber 1988 to:Dr. Linn Bogle, totany, university of New Hamp-shire, Durham, NH 03824. Women and minorities encour-aged to apply. UNH is an Afinnative Action/Equal Employ-ment Opportnity Employer.

CURATORIAL POSTIIONIN ORNITHOLOGY

AMERICAN MUSEUM OFNATURAL HISTORY

The Department of Ornithology invites applicationsfrom ornitologists with Ph.D.'s for a tenure-track cura-torial position. Research and training should involveevolution and systematics of birds; interest in museumspecimens is desirable. The Department maintains largeworldwide collections of all avian taxa. The primaryresponsibility of the successful applicant will be to con-duct an active rcesarch program. Other responsibilitieswill indude curation ofthe collection, assistance with thepreparation ofexhibits and with educational programs ofthe Museum, administration, and other Departmentalduties. Rank and salary will bc determined on the basis ofqualifications. Full Muscum benefits apply. Interestedapplicants must submit the following information: (i)curriculum vitae, (ii) statement of long-term researchobjectives, (iii) complete bibliography and sample publi-cations, and (iv) lettcrs of recommendation from at lcastthree professionals acquainted with the applicant's quali-fications and accomplishments. Submit to:

Dr. Francois VuilleumierCharman, Search CommitteeDepartmnt of Ornithology (S)

American Muscum ofNatural HistoryCentral Park West at 79th Street

New York, NY 10024An Equal Opportunity Employer

DIRECTOR-CENTER FOR GREAT LAKESSTUDIES/Great Lakes Research Facility, University ofWisconsin-Milwaukee (UWM). Major research unit ofThe Graduate School of UWM seeks applicants for aDirector to develop and promote inter plinary re-search programs, manage the Research Facilit, andfoster expansion of research activities and laboratoryfacilities. Must have Ph.D. qualifications for tenuredfaculty appointment, record of research achievmnt inlake and ocean science or technology, and managementexpenence in marine research programs. Salary competi-tive. Apply with letter, curmculum vitae, names andaddresses of three references by 1 January 1989, to:George W. Keulks, Dean, The Graduate School andResarch, University of Wisconsin-Milwaukee, P.O.Box 340, Milwauk, WI 53201. An Affirmative Action/Equal Opportunity Employer.

PERSONNEL PLACEMENT 315

POSITIONS OPEN POSITIONS OPEN

Wyeth-Ayerst Laboratories is a world leader inresearch and development in the pharmaceuticalindustry. We currently have a unique opportunity foran Immunologist (PhD) with experience in viralsystems to join a multi-disciplinary team engagedin the development of recombinant human viralvaccines at its Biotechnology and MicrobiologyDivision in Radnor, PA.

The ideal candidate will have 2-3 years post-doctoralexperience which should include expertise in tissueculture, virus propagation, and viral serology.Experience in hybridoma techniques is desirable.

We offer a highly competitive salary, extensivebenefits and a state-of-the-art environment in aconvenient suburban location. Qualified candidatesare invited to submit CV or resume with salaryrequirements in confidence to: WYETH-ERSTLABORATORIES, INC., Recruitment Manager,Position #298, P.O. Box 8299, Philadelphia, PA

19101. Equal Oppor-VWYETH tunity Enployer,

tAV AYERST M/F/H/VresponsesTM encouraged.

l-. gg l.

Ph.D. scientist )A.I.D.S. Research

As Part of our expanding activities in A.I.D.S. antiviraland vaccine research, the Merck Sharp and DohmeResearch Laboratories is able to offer a significantcareer research opportunity. Our laboratory studiesare wide-ranging and encompass most aspects ofhuman immunodeficiency virus (HIV) biology.Our commitment to A.l.S. research is long-term andwe are searching for an exceptional scientist at thePh.D. level to join the program. Previous research ex-perience with HIV is highly desirable However, all ap-plicants with experience in virological studies will beseriously considered.An excellent salary and a superb benefits programaccompany this position at our mode, state-of-the-art facilities located in suburban Philadelphia,Pennsylvania.

Please send your resume withsalary requirements to:

Manager, Research Personnel, WP42-2

Merck Sharp & DohmeResearch Laboratories

West Point, PA 19486EEO/AANH/Employer

Enzo Biochem, Inc., a dynamic healthcare companylocad in New York City, isd c tedlth de pmenof antibody-based and DNA probe-sed diagnostictests. The company offers challenging positions, com-petitive salaries and excellent benefits. Enzo is activelyseeking highly motivated professionals for the followingpositions:

Ph.D. Immunochemist(Protein Chemist)

Candidates should have experience in developing im-munodiagnostic kits, non-radioactive labeling of prtinsand using monoclonal antibodies for immunopathologyand immunohistochemistry. Industry experiencepreferred.

Ph.D. ImmunologistCandidates should have experience in the develpmentand production of monoclonal antibodies. Previous ex-perience in antibody purification required.

Ph.D. Molecular BiologistCandidates should have experience in nucleic acidhybridization, cloning, probe development and signalamplification. Postdoctoral experience preferred.Submit resume, including references, to:

ENZS9 BKDCHEM, INC.Personnel 0Opm'tment-SF

335 Hudson Stre, New York, N.Y. 11001Equal Opportunity Emplyer MIF

GRADUATE STUDY IN MICROBIOLOGYAT COLUMBIA UNIVERSITYPredoctoral Fellowships

* Prokaryotic and eukaryotic gene structure -

Regulation of gene expression ' Microbial, yeastand viral molecular genetics - Developmental

biology - Animal virology ' Genetics and cellularregulation of the immune response - Chemical

and viral carcinogenesis

The program provides a broad experience in micro-biology, immunology and cell and molecular biology, inaddition to rigorous research training. Full financialsupport is provided including tuition, fees and a livingallowance, which is currently $12,000 per year. Hous-ing is available in the area of the Medical Center inupper Manhattan and convenient, inexpensive publictransportation makes it possible for students to com-mute from other areas and to enjoy the vast culturalresources of New York City.

For further information please write toGraduate Program DirectorDepartment of MicrobiologyColumbia University701 West 168 StreetNew York, NY 10032

0

I

k

NEURO06ENETICCORPORATION

Molecular Biology andMolecular Pharmacolovy

GroUP Leaders

Leadership positions are availableat Neurogenetic Corporation,Paramus, New Jersey, for the headsof its molecular biology and mole-cular pharmacology divisions.The Section Head for the Molecular

Biology division should have at leastfour years experience beyond thePh.D., including experience in genecloning, procaryotic and eucaryoticexpression systems, and mutagenesis.The Section Head will supervise a

group of ten scientists.The Section Head for the Molecular

Pharmacology division should haveat least four years experience beyondthe Ph.D., including experience inbinding assays, cell biology, secondmessenger systems and neurophys-iology. The Section Head will super-vise a group of ten scientists.

Neurogenetic Corporation is arapidly growing company involvedin the development of diagnostic andtherapeutic agents for the treatmentof neurological and psychiatric dis-orders. The company offers an excel-lent compensation package as well as

the opportunity to contribute to thedevelopment of new treatments forhuman diseases. All applications willbe kept confidential. Applications,including a full curriculum vitae andthe names and addresses of threereferences, should be directed to:

Neurogenetic Corporation215 College Road,Paramus, NJ 07652

An Equal Opportunity Employer

Glaxo Inc. is not only one of the Top 10 ethicalpharmaceuticalfirms in America, we're alsothefastest growing research-oriented companyin the country. As such, we can offer exceptionalcareer opportunities, state- of- the-artfacilities,and afirm commitment to producing the mosteffective pharmaceuticals that experience,imagination, and advanced technology cancreate. Join Glaxo, and applyyour knowledgeand career ambitions where they'll do you themost good.We currently have thefollowing position avail-able at our Corporate Headquarters located inResearch Triangle Park, N. C.

RESEARCH SCIENTISTDrug MetabolismThis key individual will bepart ofan inter-disciplinary department applying modernsynthetic, analytical and biochemical methodsto drug discovery and developmentprograms.Major responsibilities will include thedevelopment ofextraction and HPLC methodsfor the purification ofmetabolitesfrombiological matrices and the use ofspectroscopictechniquesfor their identification. The abilityto carry out synthetic schemes developed by asenior staff member and the independentdevelopment ofquantitative HPLC and GCassays are also required. Familiarity within vitro drug metabolizing systems is desirable.Qualifications must include a BS Degree with5 or more years ofrelevant experience or a MSDegree with 3-5 years of experience.At Glaxo Inc., growth opportunities and up -to -date facilities are complemented by a location(near Raleigh/Durham) that has excellentresources in close proximity. Prestigiousuniversities, scenic vistas, lively recreationalareas, and exciting cultural opportunities areall a part of the daily life of the Glaxoprofessional. Further; we reward talent andcreativity with an excellent salary and benefitspackage (including a completely equipped, on -site athletic facility). Candidates interested inthis position, please send resume, includingsalary history to:

Human Resources DepartmentJob #8625B915

GlaxoIncnPO Box 13398

Research Triangle Park, N.C. 27709 N(No Phone Calls, Please)

N- Private Agency Referrais, PleaseAn Equal Opportunity Employer MIF/H/ V U

Paving the way to a healthier world.

I

POSITIONS OPEN

UNIVERSiTY OF GLASGOWDEPARTMENT OF GENETICS

ROBERTSON CHAIR OF BIOTECHNOLOGYApplications are invited for the Roberton Chair of

Biotechnology in the Deparmenet of Genctics, tenablefrom 1 April 1989. This Chair will be housed in a newRobertson Institute of Biotechnology. A recent majorbenefaction to the Univcrsity has led to the immediatecreation of the Chair and the building of the Institute by1990.The successful candidate will havc a proven record of

research achievement and will have expericnce in foster-ing academic and industrial collaborations in the interdis-ciplinary areas that reated to biotechnology.

Further particulars can be obtained from: The Aca-demic Personnel Offie, University ofGlasgow, Glas-gow, G12 8QQ, where application (threc copies; onecopy in the case ofoverseas applicants), giving the namesand addrse of three referees, should be lodged on orbefore 4 November 1988.

In rcply please quote Re£ No. 6327SK

DEANCOLLEGE OF PHYSICAL

AND MATHEMATICAL SCIENCESNORTH CAROLINA STATE UNIVERSITY

Applications and nominations are invited for the posi-tion of Dcan, Colle of Ph ical and MathematicalSciences effective 1 Juy 1989. Thc college has a compre-hensive research program as wel as significant teachprograms in graduatc and undeQraduate levels. Thedean should be a person with a high encrgy level,integrity, proven kadership ability, a record of icholar-ship, and an eamned doctorate in an appropriate field.Appicants should submit a letter of initere r6sume, andnames, addresses, and telephone numbers of at leastthreereferences by 1 Decembe 1988 to: Mr. Wiliam H.Simpson, Secrtary oftheU ,North CarolinaState University, Bx 7001, Raleg, NC 27695. AnAjfirmative Action/Equal Opportunity Employer.

DENDROCHRONOLOGIST. The Laboratory ofTree-Ring Researh invites applications for a tenure-

rack ulty positon, avadabl 1989. It is envis-aod that appointment will be at asssant professor kvel.le succesfl applicant will be capable of developingimaginative uses ofthe environmental record held in treenings and possibly also similarly annual layers of biologi-cal or geoloncal origin. A Ph.D. is required as isevidence ofe ve creatvity in recovering enviromnen-tal history. Applications received by 1 December 1988will be gpven ist consideration. If no suitable candidateis identified, then late applications will be reviewed. Sendcurriculum vitae, bibliography with copies of selctedpublications, statemcnt of research interest and thenames and addrsses of three referoes to: William J.Robinson, Laboratory of Tree- Research, Uni-versi ofArina, Tucn, AZ 85n1. The Universityof Arizona is an Equal Opportunity/Ajirtnative Acion Em-ployer. Women and minorities are encouraged to apply.

DIRECTOR

RESEARCH INSTITUTEPosition available for Ph.D. with broad research and

admiistrtive expericnce to direct a cardiovascular andpulmonary research insitute. Thc successful candidateshould havc cxperence with myocardial protection, newperfusion methods, left-ventricular assist devices, lasersurgery, heart transplantation research, or valve andblood vessel transplantation research.

In addition, the candidate will be able to bring about abalance between basic and clinical research, as well asdirect efforts in exramnural grant writing, grant distribu-tion and the direction and planning of the scientificactivities of the research institute.The research insttute adjoins a renowned specalized

hospital in Ncw Jersy. For confidential cnsdeatplease forward yourr to:

R-1, P.O. Box 17182Philadelph, PA 19105

Please respond on or beforc31Oporbir 1988.

Equa Oppormnity F-ploer

INM

The Insttut fllr Neue Materialien and the Universitatdes Saarlandes invite applications for the position of

DIRECTORofthe INSITrUT FURNEUE MATERIALEEN GEM.GMBH, Saarbr0cken. The directorwill be simultaneous-ly appointed

FULL PROFESSOR (C4)in the Faculty of Mathematics and Science, Departmentof Materials Science, Universitat des Saarlandes. Theposition of Director indudes the scientific responsibility

r one of the departments of the Institute. The reawork of the succesul candidate should bc concentratedon the production ofnew materials and/or the character-ization of such subsances

Applicants should be scientifically qualified in one ormore of the folkloing ficlds:

Mctallic materialsCeramic materialsSemiconductors

The Irit ftir NeueMameriaien is a research fialityoftheSaarland and cooperaam with the Universitt des Saarandes

in both reseanch and grate educa as wel as with otherruah i and ixhiual .

Applications (rdsunc, scicntific bacund and bibli-ograp?hy) should be submitted by 15 November 1988,to: Xhe Managing Director, Insttut-fir Neue Mater-ilien Gmbh, Professor Dr. H. Gliter, Univrseitltdes Saarndes, Geblude 2, D-Saarbrfcken, WestGcmay

DIRLECOR OF BIOTECHNOLOGYPROFESSOR OF BIOCHEMISTRY

VIRLGINIA POLYTECHNIC INSTITUTEAND SrATE UNIVERSITY

Applications and nominations are invited for the posi-tion of Director of Biotechnology and Associate or FullProfessor of Biochmistry. The Dirctor will lead thexpansion of biotednology/molecular biology, developand coordinate interdisdp inary i on and cprograms, ovcrsee service facties and training labora-tories fr biotechnology, allocatc resources to specprograMS, and participate in reruiting new faculy. TheDirecor will be a faculy member and lead a strongresearch program in the Department of Biochemisty.The Department of Bioche y is e nding researchin protean biotechnology and eukaryotic molecular biolo-gy. Applicants shiold the Ph.D. and have experi-cnce at an academic institon.

Applcations and nnunans will bc recived until thepoion i.s fiLbed. Applicant scrnin~ will begn on 15December 1988. A wanshuld lde a dciptionof research program, vites andwkephne nubers ofdree rferences. Send to:

E. RL StoutAsooiate Provost for Reearch

Research DisonVirginia Tech

Bl ug, VA 24061-0244Virginia Tech is an Equal Opportunity/Airmnative Action

Employer.

DIRECTOR, NEW PRODUCT DEVELOP-MENT-Establshed manufacturer of scientific instru-mcnts used in celular electrophysiology, cell biology,neuropharnacology, and biophysics seeks a director,New Product Development. Candidate must have celc-trical nincerin de#ree; advanced degrees in eitherengineenng or bioloscal sciences; and several years oflaboratory excpeence m one or more ofabove mentionedfilds. Responsibilities include partcipation in new prod-uct decision making process, overalf toenical directionof new developments, field evahluations, and productioncngmcering.Edividul must be agresives, personable, a "can-do"

achiever, and have exc'clent coummand of English lan-guage. Compensation in $40,000 to $50,000 per yearrange, plus benefits. Send resume and salary history to:Box 159, SCIINCE.

DIRECTORThe Science Muscum of Minnesota seeks fuill-time

direcomr for its newly established St. Croix Fidld ResearchCenter. Responsibilities: Deveop rsearch and educa-tional programs rlating to the plants, animals, andgeneral ecology of the St. Croix and its drainage basin;develop and maintain facilities (house, labs, etc.); super-vise on-site Field Center and contract staff, assist inpreparing exhibits/proerams for main museum (800,000annual visitors). Qualifications: Ph.D. in biological sci-ences (aquatic focus preferrd) or equivalent researchrecord; development and administrative experience;demonstrted commitment to both scholarship and pub-lic education. Salary commensurate with expeiencc.Send letter of interest, curriculum vitae, and three refer-ences by 1 November 1988 to: Dr. Louis B. Cast-grande, Senior Vice Predt, Science Museam ofMinnsota, 30 East 10th Stroet, St. Paul,MN 55101.

DIRECTORDEVELOPMENTAL NEUROSCIENCE

CENTERVanderbilt University's John F. Kcnnedy Center for

Research on Education and Human Development seeksa senior individual with a record ofoutstandig researhaccomplishments and high scholarly achievement in thearea of developmcntal ncurobiology. Rarch in anyarea of developmental neuroscince is appropriate to theposition. The applicant's research bacgound shouldeither rclate directly to mental retrdation or bc suffi-ciently broad to bc related to that of other investigatorsin mcntal retardation research. The tenured positionoffers the opportunity for developing a new center fordevelopmental ncurosciencc at Vanderbilt while at thesamc time joining Vanderbiles already strong and cx-panding cffort in ncuroscicnce.Nominations and applications should bc forwarded

with curriculum vitac and names of refcrees to: Profes-sor VivicnA Casagrande, Neuroscience Search Com-mittee, Box 74Peo College, Vanderbilt Univer-sity, Nashville, TN 37203 (ITNET address: CA-SAGRVA@VUCITAX). Women and minorities areencouraged to apply.

WESLEYAN UNIVERSITYDIRECTOR

EDUCATIONAL STUDIES PROGRAMWesleyan University seeks an individual of accom-

plishment to direct its Educatonal Studies Progrm.Requirements are a strong scholarly and/or practitioner'srecord in education; a doctorate; broad school experi-ence, preferably in primary or secondary as well as highereducation; demonstrated leadership ability. Please send

plications and ominaions by TDecember 1988 to:Bqd,Deprt (of Government, Public

f Waian University, MidktownCT06457. Teephone: 203-347-9411, Extenion: 3103.AJfinnative Acion/Equal Opporunity Employer.

ENVIRONMENTAL SCIENCESUNIVERSITY OF MASSACHUSETTS

AT BOSTONThe Environmental Sciences Program seeks to fill a

tenure-track faculty position in the area ofphytoplankmonecology, rank open. A doctoral degree is requred andpostdoctoral experience desired. The progam is a doc-torl degree granting program training sudents in boththe natural and social sciences largely focused on marinecoastal isues. Duties will include teaching at the gradu-ate level. Research interests should include, but not beneessarily restricted to, coastal primary production.Areas of immediate pramm c interest are the pro-cesses controlign eutrophication, nutrientcycling, and c-benthic coupling. The successfulcandidate will join an interdisciplinary group ofscientistswhose primary interests include organic and inorganicgeochemistry and biogeochemistr, benthic ecoly,aquatic toxicology, g coastal estuanephysics, marine policy, en ml economics andenvironmental law. Send r&sum6, cover letter, and thenames of at least three references to: ChairPhytoplankeon Ecologist Search Committee, Envi-ronmenl Scines Pr m, Uniersityof Maa-chusetta at Boston, Boston, MA 02125. Applicationreceived by 4 November 1988 will bc given pnorty. AnAffirmative Action/Equal Opportunity/Title IX Employer.

SCIENCE, VOL. 2423I8

POSITIONS OPEN POSITIONS OPEN

FACULTY AND POSTDOCTORALPOSITIONS AT THE

UNIVERSITY OF MEDICINE ANDDENTISTRY OF NEW JERSEY.NEW JERSEY DENTAL SCHOOL

Applications are invited for the positionsatthe newly established Dental ResearchCenter. Seeking M.D., Ph.D. or D.D.S.individuals wifth interest and expenence inthe area of chemistry and function ofsalivary and gastro-intestinal secretions.Preference will be given to molecularbiologists, biochemists, immunologists,and physiologists pursuing research inglycoprotein synthesis and processing,biochemical pharmacology, enzymology,lipid and protein metabolism, connectivetissue and bone nineralization, membranereceptors and signal transduction, andimmune and nonimmune mechanisms inthe health of the oral cavity.Send resume, statement of research inter-ests, and references to: Dr. BronislawL. Slomiany, Director, DentalResearch Center, UMDNJ-NewJersey Dental School, (S), 110Bergen Street, Newark, NJ07103-2425.

The UMDNJ is an Affirmate Action/Equal Employment Opportunity Employer MWF/HN.

NE_W ERSEY

ResearchVeterinarian

An equal opportunity employer

Pfizer's Animal Health Research group has anexciting array of newly-discovered compoundsfor the treatment of animal diseases and forimproving the health and productivity of foodanimals. We therefore need to enhance ourclinical research and development team andare seeking applications from qualified peoplewho would like to use their scientific organiza-tional skills in a multi-disciplinary project-teamenvironment.We currently have a position on our clinicaldevelopment team in our Terre Haute, Indianafacility which initially will involve contributingto the design of clinical field programs acrossthe U.S., organizing the clinical testing, and in-terpreting the results. This position affords onean outstanding opportunity for a personal andoriginal contribution to the development ofmajor new products in one of the world'sleading health care companies.If you are a veterinarian or have a post-graduate degree in a relevant discipline withsome clinical or research experience and havegood interpersonal communication skills, wewould like to hear from you.Pfizer offers excellent compensation, com-prehensive benefits and opportunity for profes-sional recognition and growth. If interestedand qualified, please send a current resume inconfidence to: Christina Batjer, Senior Person-nal Supervisor, Pfizer Inc., P.O. Box 88, TerreHaute, Indiana 47808.

DNA SEQUENCING This position is an exciting opportunity for a molecular biologist to combineWORKSHOP ~~~~teaching, marketing and travel. Responsibilities include developing, scheduling,WORKSHOP ma g and teaching short courses in dideoxy sequencing technology. TheINSRUCTOR ideal candidate will have significant laboratory experience in sequencing DNA

and exceptional organizational and interpersonal skills. Approximately 50% travelis required.

TECNNICAL SERVICES Apply your technical expertise in Molecular Biology and interpersonal skills toREPRESENTATIVES this critical customer service position. Required qualifications include an M.S. or

B.S. with laboratory experience in Molecular Biology or a related field. A thoroughknowledge of standard Molecular Biology laboratory techniques is required toprovide technical assistance on the use of IBI products and related techniques.Familiarty with genomic analysis is desired.

SOFTWARE TECHNICAL IBI is currently seeking candidates for the position of Software TechnicalSPECIALIST Specialist for its exciting new line of sequence analysis software. This position

would involve technical support for sales as well as training for software users.The ideal candidate will have basic understanding of recombinant DNA tech-

niques and familiarity with MS-DOS and Macintosh computer systems.

SOFTWARE PRODUCTDEVELOPMENT

IBI is currently seeking a Programmer/Biologist to direct the developmentand maintenance of our sequence analysis software for microcomputers. Theideal candidate must have a graduate degree in the Biological Sciences and havea proven track record in developing software for microcomputers. A proficiencyin C is required and experience with both PC-DOS and Macintosh systems helpful.

Interested candidates should mail their resume to:Position TitleInternational Biotechnologies, Inc.A Kodak CompanyP.O. Box 9558 * New Haven, CT 06535

An Equal Opportunity Employer 'AA

I

POSITIONS OPEN

ENVIRONMENTAL SCIENCE MANAGERFreese and Nichols, Inc., a Texas-based consulting

engineering firm, has a challenging opportunity for anestablished- individual to guide the expansion of andperform business development activities for our Environ-mental Science Department. This department preparesimpact statements and assessments for engineering anddevelopment projects with particular ep}is on envi-

ronmental evaluations for federal and state permitting.

The department manager will direct projects relating tothe environmental impact of water supply reservoirs,water and wastewater treatment plants, water qualitymodeling, wastewater reuse, public transportation andflood control.

Required qualifications: M.S. in environmental sci-ence or related degree, 15 years of experience in theenvironmental field, experience as an expert witness in

hearings or litipation, management experience and mar-keting capabilities, knowledge of the guidelines andregulations of federal and Texas agencies responsible forenvironmnental protection.

Please submit rdsume to: Personnel Department,Freese and Nichols, Inc., 811 Lamar Street, FortWorth, TX 76102. Equal Opportunity Employer.

FACULTY POSMONThe Microbiology Department of The University of

Texas at Austin has an opening for an assistant professor.Appointment at a higher rank will be considered forinfividuals with an outstanding record of independentresearch. We are searching for an outstanding molecularbiologist who can devdop a creative, productive rescarchprogram. Preference wibe given to individuals withmterest in Microbial or Yeast Biochemistry, PathogenicMechanisms, and Developmental Processes in Proway-otes or Lower Eukaryotes. However, highly qulifiedindividuals with interests in molecular biology outside ofthese areas also will be considered. This is an outstandingopportunity to join an excellent Department during aperiod of expansion. Please submit curriculum vitae,incuding names, and addrcsses of three references and a

summary ofresearch interests to: Microbiolo Depart-ment Search Committee, T'he Univrsity o Texas atAustin, Austin, TX 78712-1095. The University ofTexas is an Equal Oppotunity/Afirmative Action Employer.

FACULTY POSmON-Synthetic Organic Medici-nal Chemistry. A tenure-track position is available in fall1989 for an outstanding scientist with a Ph.D. inmedicinal or organic chemistr. Appropriate posdoctor-al experience is desirable. Although we anticipate fillingthe position at the assistant professor level, candidates athigher ranks will be considered. The applicant will beexpected to develop a strong, independent, and external-ly-funded research program and to participate in theteaching of both undergraduate and graduate depart-mental courses in medicinal and/or orpanic chemistry.Applicants should submit curriculum vitae, a brief out-line of future ch plans, and should arrange to havethree letters of recommendation sent to: Prossor Da-vid E. Nichols, Chair, Faculty Search Committee,Departmcnt ofMedicinal Chemistry and Pharmacog-nosy, School of Pharmacy and Pharmacal Sciences

Purdue University, West Lafayette, IN 47907. Re-view of applications will commence 1 November 1988and continue until the position is filled. Purdue Is an EqualOpportunity/Affinnative Action Employer.

FACULTY POSMON AVAILABLEApplications are invited for a tenure-track position in

the Department of Pharmacology, University of SouthCarolina, School ofMedicine. Ph.D. and/or M.D. degreeand postdoctoral experience required (rank open). Thesuccessful candidate will be expected to devlop anindependent research proram which merits extramuralsupport and to teach m cal/graduate students. Prefer-ence will be given to individuals whose research usesmolecular or biochemical techniques to study biologicalactions. Candidates with backgrounds in biochemistry,physiology, pharmacology, or other biomedical scienceswill be considered. Individuals should submit curriculumvitae, statement of professional goals, and the names ofthree references: Dr. D. 0. Allen, Chairman, Depart-

ment ofPharmacology, Universit ofSouth Carolina,

School ofMediane, Columbia, SC 29208. The Univer-sity of South Carolina is an Equal Opporunity/AffirmativeAction Emnployer.

FACULTY POSITION: Cornell Collcge, an under-duate liberal arts college of 1100 students and 70

faculty in Mount Vernon, owa, pkas to make a full-tinmetenure-track apointment in its chemistry departnent inthe fall of 1989. Ph.D. required; teach analytical, inor-ganic, and general chemistry. Interdiscipnary interestswelcome. Send letter of application, curriculum vitae,transcripts of both undergraduate and graduate educa-tion, and names of three references to: Dr. AddisonAult, Department of Chembtry, Corneml Collegc,Mount vernon, IA 52314. Formal consideration ofapplications will begin 15 December 1988. Cornell Col-lege is an Equal Opportnity/Afirmative Aaion Employer andactively seeks women and minority candidates.

FACULTY POSMON: TRANSPLANTATION,BIOLOGY AND IMMUNOLOGY. Permanent trackposition for persons with Ph.D. and/or M.D. degrees.Involves conducing an independent research programon some aspect of transplantation, biology su as

physiology and/or immunology with a focus towardtransplantation. Candidate expected to be competent in

basic immunology, to conduct an independent researchprogram and be willing to participate with cliniciansinvolved in a large multi-organ transplantation program(liver, renal, pancreas, heart, lung, bone marrow). Willreceive academic appointment commensurate with his/her qlifications. Startup funds for establishment of thelaboratory are available. Send curriculum vitae, a descrip-tion of reearch interests and names of three referencesto: Dr. Keith A. Kelly, Chairman, Department ofSurgery, Mayo Clinic, Rochester, 55905. AnEqual Opportnity/Affirmative Action Institution.

FACULTY POSMONS-Tenure-track for all aca-demic ranks induding full professor of biochemisty

College of Medicne, University of Illinois at Chicago.

The Department is research oriented with a strong

commitment to graduate and biomedical education. Ap-

plicants should provide curriculum vitae, names of three

references and a statement of research plans. Applicantsfor tenured positions must have current extramuralfunding and a rord of signicant research acoomplish-ments. The deadline is 2 Januar 1988 or until thepositions are filled; foreign trave cxpenses will be paid.

Areas of research intercsts:1) Studies of enzyme reaction mechanisms, protein-

protein or igand-protein interactions related to impor-tant biological phenomena such as signal transduction or

metabolic regulation using modern biochemical ap-

proaches, especally protein engineering. The Depart

ment has excellent research facilities, incling a protein

sequencer and peptide synthesizer. Send applications for

this position to: Dr. James C. Vary, Depa nt of

Biochemistry, 1853 West Polk Street iversity of

Illinois at Chicago, Chicago, IL 60612.2) Molecular biology ofgene expression in vcrtebrate

or cell culture systems at the lvel of transcriptional

control and processing. The Deparmt is strong in thisarea and, with the College of Medicine, is committed o

furter epansion of this group. Send applications forosition to: Dr. Robert Stord, DeptnSt ofOemisty, Uniersity ofIllinois at Chicago, 1853

West Polk Street Chiago, IL 60612.The University of Ilinois is an Affirmative Action/Equal

Opportunity Employer.

FACULTY POSMONS IN

CELLULAR AND MOLECULAR BIOLOGYApplications are invited for a tenure-track position in

the Department ofCell Biology and Anatomy at North-western University Medical School. This position is atthe assistant professor level. Applicants must have aPh.D. or equvalent degree, with msearch experience in

cellular and/or molecuar biology. Applicants will bescreened with respect to their ability to carry on vigorous

research programs and to participate in departmental

teaching proSrams. Send complete curriculum vitae,brief desciption of research interests, and at least three

letters ofrecommendation by 1 December 1988, to: Dr.Robert D. Goldman, Departmcnt ofCell Biology andAnatomy, Northwestern University Medical School,303 East Chicago Avenue, Chicago, IL 60611. North-westem University is an Equal Opportunity/Affinnative ActionEmployer and invites applicationsfiom all qualified individuals.

320

COLBY COLIEGEtwvite8 applcationa from

PLANTMOLECULARBIOLOGISTS

for a tenure-track position as Assistant Pro-fessor or Associate Professor of Biology.This position may include appointment toan endowed chair. Candidates should havea Ph.D., a strong commitment to under-graduate education, broad training and in-terest in the botanical sciences, and specialinterest and expertise in the molecularaspects of plant biology. Familiarity withliberal arts colleges, teaching experience, -

and/or post-doctoral training are desirable.Responsibilities will include teaching inintroductory courses and in advancedcourses in the successful candidate's areasof specialization. An active research pro-gram, including supervision of under-graduate research, will be expected. Sub-mit letter of application, statement ofteaching and research interests, curriculumvitae, reprints of publications, undergrad-uate and graduate transcripts, and thenames and addresses of three individualswho could serve as references to: ProfessorArthur K. Champlin, Chair, Department ofBiology, Colby College, Waterville, ME 04901.Completed applications should be receivedby 15 December 1988 Colby College is anAffirmative Action/Equal OpportunityEmployer and encourages applicationsfrom women and minorities.

NOVA FNAURIIAEVTIUL eRIoUTIuno, aleading research and devebpmet company inBaltimore, MD, is accepting applications for animmediate opening in the Division of DrugDiscovery at the level of Staff Scientist/SeniorResearch Associate. The ideal candidate willhave a background in neurotransmitters, neuro-modulators and/or neuroactive peptides as theypertain to interacting or regulating the immunesystem The specific experience being soughtincludestissue culture including primaryculimmunoassays, monoclonal antibody produc-tion and more general chromatographic or bio-chemical techniques. Thesuccessful candidatewill be expected to (1) independently direct aprogram targeted toward the development oftherapeutic approaches for myelin-based dis-orders of the CNS, (2) actively participate in theidentifcation and characterization of syntheticantagonists and (3) input to the staff of theDivisiononotherscientificprograms. Responsi-bilities will include the daily administration of atissue culture facility and a laboratory groupQualifications required include a PhD or MDdegree and at least 2 years of postgraduatetraining.

NOVA PHARMACEUTICAL CONHOuAnIN isan equal opportunity empioyer offering a com-petitive compensation and benefits packagewhich includes relocation expenses. Interestedindhiduals shotid send their resume toc L Furl

J1 N111IM sn es mslC sp.,Frpedr Csbtr, Ualtlm.w EO 21224-273. WE

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POSITIONS OPEN

IL/o#rs/

A.

GENE-TRAK Systems in

just two years has become

one ofthe largest groups in

the world dedicated to the

commercialization ofDNA

probe basedproductsfordiagnosing infectious

diseases.

SNIOR~IENTIS

Position available to furtherdevelop methods of replicatingnucleic acids for use in DNA/ RNA

probe hybridization assays.

Applicants must have substantial

experience with in vitro nucleic acid

replication systems and knowledge

of RNA and DNA polymerases,

transcriptases, or replicationcomplexes. Requires Ph.D. in

molecular biology or biochemistry

and at least 4 years'post-doctoralexperience with a svtrong publicationrecord.

Many positions available for

molecular biologists to develop

novel assay formats and to optimizenon-radioactive detection methods.

Requires BS/ MS degree in the

biological sciences with 2 or more

yearsiexperience in the handlingand manipulation of nucleic acids.

GENE- TRAK Systems,located in the western

suburbs of Boston, offers a

lucrative compensation andbenefits package thatincludes equity participation.Send your resume to: BrianMazar, Human Resources

Director, Dept. S 10-28,

GENE-TRAK Systems,31 New York Avenue,

Framingham, MA 01701.

An equal opportunity employer

~GENE-TRAKI SYSTEMS

HHMI-NIH Research Scholarsat theNational Institutes of Health

The Howard Hughes Medical Institute (IHMI) and the NationalInstitutes of Health are accepting applications for the 1989-1990class of Research Scholars to begin in the summer of 1989.

* HHMI-NIH Scholars are selected from medical schools, usuallyafter the first two years, for a year of laboratory research at theNIH in Bethesda.

* Scholars must be U.S. citizens or permanent residents attendingmedical school in the United States or Puerto Rico.

* Scholars are paid as employees of HHMI and housed on theNIH campus.

* Applications must be received by January 15, 1989.Candidates will be notified of results by April 1, 1989.

* Application kits and brochures have been sent to the deans'offices of all medical schools. Additional kits and brochures can

be obtained from:

Howard Hughes Medical Institute1 Cloister CourtBethesda, Maryland 20814-1460(301) 951-6710

HHMI is an Equal Opportunity Employer.

Howard Hughes Medical InstituteAnnounces a New Program

Medical Student Research Training FellowshipsThe Howard Hughes Medical Institute will award up to 60 fellowshipsto medical students who wish to spend a year in intensive research duringthe 1989-90 academic year.

Eligibility: I

* Applicants must be attending a U.S. medical school, but there areno citizenship requirements.

* The fellowship research may be undertaken at any academic orresearch institution in the United States.

* Students enrolled in M.D./Ph.D. programs are not eligible.* Applicants may not apply simultaneously to the HHMI-NIH

Research Scholars Program.Fellowship Awards:

* $12,300 stipend.* $7,700 allowance to the fellowship institution for research supplies

($4,000) and institutional expenses ($3,700).Deadlines:

* January 13, 1989, for completed applications.* Awards announced by early April 1989.* Fellowship tenure must begin by October 1989, at the latest.

For information:Call (301) 571-0324or write:

Medical Student Research Training FellowshipsOffice of Grants and Special ProgramsHoward Hughes Medical Institute6701 Rockledge DriveBethesda, Maryland 20817

The Howard Hughes Medical Institute welcomes all qualified applicantsand encourages women and members of minority groups to apply.

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SENIOR

SCIENTISTPhD Chemist and/or Toxicolo-gIst Is needed by a NorthCarolina based manufacturer,to play a key role In the areasof product quality and newproduct development. Candi-dates should be thoroughlyfamiliar with the theory of ad-vanced analytical Instrument-al techniques and have fiveyears In functional Interactionof analytical chemistry In toxI-cology disciplines Experiencein residue analysis a plus. Mustbe an able communicatorwith top management team.Smoker preferred. Excellentstarting salary and benefitpockage Send resume to:

VP-Employee Relations

*|| Liggett & Myersq"'obacco Co.

P.O. Bx 1572. Durham, NC 27702Equ Opportniy E Mp I FIdVlI

Albuquerque, NM

TOXICOLOGISTStaff position available atLovelace Inhalation ToxicologyResearch Institute for tox-icologist with orientation to-wards multidisciplinary teamapproach to solving researchproblems. The individual weseek will have doctoral leveltraining in toxicology and havecompleted a rigorous postdoc-toral fellowship or possessequivalent experience in anarea compatible with the re-search interests of the institute.A background in chemistry,biochemistry, cell or molecularbiology, pathology, immunolo-gy, particle deposition/clear-ance, physiology, pharmacology,pharmacokinetics, metabolismor other fields will be con-sidered. Competitive salary andfringe benefit package. Submitresume to Personnel Unit,Dept. M, P.O. Box 5890, Albu-querque, NM 87111. We are anEqual Opportunity/AffirmativeAction Employer.

MAX-PLANCK-INSTITUT FORBIOCHEMIE

MUNICH-MARTINSRIED

POSTDOCTORAL POSITIONApplications are invited from physi-cists or physico-chemists for (ini-tially) a three-year appointment tojoin a group within the Departmentof Structural Biology (Professor W.Baumeister) using Scanning Tun-neling Microscopy (STM) for inves-tigating the structure of biomole-cules. Currently, our STM is usedin the topographic mode; a secondinstrument specifically designedfor scanning tunneling spectrosco-py is under construction.

Experience in Scanning TunnelingMicroscopy/Spectroscopy or in IR/Raman spectroscopy will be ad-vantageous but not essential.

Salary scale: DM 53,000 to DM57,600 according to experience.

Please send applications includingc.v. and names of two referees to

Dr. R. Guckenberger,Max-Planck-institut fOr BlochemleD-8033 Martlnsried bel MOinchen,F.R.G.

WORKSHOP

MOLECULAR AND CELLULARBIOLOGY OF

PLASMINOGEN ACTIVATIONApril 17-21, 1989 atBrookhaven National

Laboratoty, Long Island,New York

This second international workshopwill include such topics as: Regula-tion of Gene Activity-Cis Elementsand Trans Factors; Role in Cell Physi-ology and Pathology; Inhibitors; Rolein Development and Reproduction;Protein Structure and Function; andReceptors.

Participants will be selected solely onthe basis of abstracts (one page) sentby December 5th to Drs. W.F. Mangel,F. Blasi, K. Dano & D. Rifkin, BiologyDepartment, Brookhaven NationalLaboratory, Upton, NY 11973 USA.

IF RESEARCHPHARMACOLOGIST

SCIENTIST

Nelson Research, a wholly-owned subsidiary ofEthyl Corporation, situated on the campus of theUniversity of Califomia at Irvine, is a pharmaceuti-cal research firm committed to the discovery anddevelopment of new drugs. The Company cur-rently has an opening for a Pharmacologist

The successful candidate will be involved in:Development of in vivo and in vitro assaysto evaluate the specificity and efficacy ofnew chemical entities developed by thecompany.

Coordination of various programs in dis-covery research with academic and indus-trial scientists worldwide.

Qualified candidates will have a Ph.D. with 3 ormore years postdoctoral experience in generaland cardiovascular pharmacology. Industrial phar-maceutical experience is desirable.

Excellent oral and written communication skillsare essential.

Nelson Research offers a professional environ-ment and competitive salary and benefits. Inter-ested candidates may send resume with salaryhistory to:

Personnel ManaerNelson Research & Dewlopment Company

1001 Health ScInoes Rd. WestIrvine, CA 92715

An Equal Opportunity Employer

n~~~~~~~~~~~~~~~(Science, Technology ancd Research

If you are planning for the future and arelooking for an opportunity to become es-tablished with an industry leader, we in-vite you to apply for the following posi-tions.

RESEARCH PROJECT LEADERWe desire individuals who are innovativeand strong team players to managebench level research and development ofEIA/RIA based products. Candidatesmust possess an MS in Bio-Chem orrelated field with 3-5 years of experiencein diagnostics.

PROTEIN CHEMISTCandidates must have experience with alltypes of protein/peptide purification tech-niques, quantitation mrr s using AAAand conjugation of enz es to antibod-ies or proteins/peptides.T position willsupport both production and R&D func-tions. MS or PhD in Bio-Chem or relateddiscipline necessary. A knowledge of im-munoassays and EIA desirable.

INCSTAR, an invitro diagnostics com-pany, is located in historic Stillwater, MNjust 25 minutes from the cultural and en-tertainment attractions of Minneapolis/St.Paul. We offer an excellent compensationand benefits package. Qualified candi-dates should submit their resume in con-fidence to: Human Resources Manager,1951 Northwestern Ave., Stillwater, MN55802.

Equal Opportunity Employer

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LEVERRESEARCH&DEVELOPMENT, thecentrahR&Dfacility for Lever Brothers Company- a leading consumerproducts manufacturer, has an immediate opening for a

to supervise a safety testing group and work on product safetyissues. As Group Leader you will work closely with R&Dgroups and develop well designed safety testing programsfocused on irritation, dermal toxicity, sensitization and pho-toallergenicity. Additionally, you will handle special assign-ments and advise research management and business units.

Qualified candidates must have a Ph.D with a strong back-ground in Toxicology and related sciences, and at least 3-5years of relevant toxicology experience.Lever offers an excellent salary and company paid benefitspackage. Send resume complete with salary history andrequirements to Mr. Jim Conti at:

[ VISK R&l) UENN 14S River Road

Edgewater, NJ 07020aia oppwottym*ywrN

Wyeth-Ayerst Laboratories, a major pharmaceutical division of a For-tune 100 Corporation, has an immediate opening for a PhD level tox-icologist to direct pre-clinical toxicology studies within the Drug SafetyEvaluation Division. Post doctoral experience is preferred although en-try level senior candidates with appropriate background will be con-sidered. The position requires broad based technical expertise andskills in interpreting safety data as well as the ability to communicateresults orally and in writing. The successful candidate will work ona cooperative basis with senior level personnel to define andcharacterize the toxicologic potential of a broad range of potentialtherapeutic agents.

The Wyeth-Ayerst Drug Safety Evaluation Division is located betweenthe foothills of the Adirondack Mountain and the shores of LakeChamplain, New York. The area offers the benefits of a relaxed rurallifestyle and a wide range of outdoor recreational activities, while beingwithin easy driving distance of such cultural centers as Lake Placid,Burlington, Vermont and Montreal, Canada. Wyeth-Ayerst is an equalopportunity employer offering the successful candidate an attractivebenefits package and salary commensurate with experience.

Please send resume and salary history to:

Gary Wagoner, PersonnelvWYETH WYETH-AYERST

LABORATORIESIf~~I~AYERST Rouses Point, New York 1297,9VW

An Equal Opportunity Employer M/F/H/V:

FACULTY POSITION IN TOXICOLOGYST. JOHN'S UNIVERSITY

COLLEGE OF PHARMACY ANDALLIED HEALTH PROFESSIONS

ASSISTANT/ASSOCIATE PROFESSOR, tenure track.Individuals with a research background in bio-chemical and environmental toxicology and appli-cants from other areas of toxicology will beconsidered. Ph.D. with post-doctoral experiencerequired. Responsibilities will include teachingundergraduate and graduate toxicology courses,training graduate students, and the developmentof a strong research program capable of attractingextramural funds. Research facilities include:AAALAC-accredited animal facilities, GC, GC-MS,NMR, AA, HPLC, LSC, gamma counter, EM (scan-ning, transmission), ultracentrfuge, and tissueculture facilities. Faculty interests encompassneurotoxicology, pulmonary toxicology, renal toxi-cology, carcinogenesis, drug metabolism, and clin-ical and forensic toxicology. We are located on a100-acre campus in a residential area of Queens,with access to Manhattan (20 min.) by subway ortrain. Application letters with curriculum vitae,statement of research interests, and names ofthree references should be sent before November15 to: Dr. Sue M. Ford, Dept. PharmaceuticalSciences, St. John's University, Jamaica, NY11439.

St. John's University is an Equal Opportunity!Affirmative Action Employer Ml

ISr. CornAgronomistSr. PotatoAgronomistESCAgenetics Corporation, a publicSan Francisco Bay Area biotech com-pany applies plant biotech to developbetter ingredients and improved cropsfor the food processing industry.

Sr. Corn Breeder/Agronomist.Join a program in specialty corns forfood processing. Position includespersonnel management, experimentaldesign, seed production, and inbredline and new hybrid development.Ph.D. and 3 + yrs. experience in cornbreeding, agronomy and extensionmanagement required.Sr. Potato Agronomist. Our TPSprogram requires experience in potatofield management, disease identifica-tion and seed certification. Ph.D.and 2+ yrs. experience in potatoagronomy/crop development required.Assoc. Potato Breeder. B.S./M.S.Send resume to:Personnel, ESCAgenetics Corporation830 Bransten RoadSan Carlos, California 94070

1%,02ESCAGENETICs

f s CORPORATION

I -M

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POSITIONS OPEN

FACULTY POSMON INANALYTICAL CHEMISTRY ATIOWA STATE UN1IVERSlTY

Applications are invited for this position which willbocome available 1 July 1989. Al rescarch areas inanalytical chemistry will receive consideration. The ap-pointment probably will be at the level of assistantprofessor; however, applications at all levels will bcconsidered. Candidates with outstanding potential for,and comnimmt to, excellence in both research andteaching are sougqht to join a faculty with a strongtradition of research in analytical chemistry. Candidateswith appropriate research interest will also be consid-cred for a joint appointment in the Ames Laboratory-USDOE. Applicants should submit curriculum vitae,transcipts, a documented summary of past accomplish-ments and an explicit statcemnt of research plans andteaching objectives tO: Analal Sear Committ do Profizsor D. 1L Hofman, Charman, ChemitrDepatment, Iowa State Universt, Ams, IA 001.Jumor applicants also should arrang for at least threeltters of om ndation to be sent. Evaluation ofapplications will begin in Novenber 1988. Women andminority applicants are encouraged to apply. Iowa State Univer-sity is an Affirmative Aaion/Equal Opportunity Employer.

FACULTY POSMON INDEVELOPMENTAL BIOLAOGY

Applications are invited for a tenure-track sition inthe field of devlopmental biology witin t Depart-ment ofBiological Sciences at Carnme- Mellon Universi-y. The leve of the appointment bc commensumtcwith the qualifications of the candidate. To apply, sendcurriculum vitae and a conci description oresearchinterest (no more than three Wp) and, in addition,have three letters of c sent to:

Dr. D. Lansing Talorb, Sar Comm eDepartment oBioOcal Siecs

~~fthAUnversPitbugh, PA 15213

Camegie Mellon University is an Equal OpportnitylAffirmative Action Employer.

FACULTY POSMONSIN THE MACROMOLECULAR

STRUCTURES GROUPOF THE DEPARTMENT OFBIOLOGICAL SCIENCESPURDUE UNIVERSITY

The Departmcnt ofBiological Sciences invites applica-tions for tenure-track facult positions that would a;-ment and complement the interests of the current eihtmembers ofthe maaomolecular stuc group, wbichalso is a component ofan intcrdisciplinary, campus wide,biochemistry program. We are individuals withinterest in the area of molcular blogy of viruses,molecular immunology, molecular dynamics, membraneprotein structure, and related topics. is antiapated thatappointments will be made over a 3-year period, at anassistant profsorial level, but qualified candidates at amore seior leve are welcome to apply. First dcadline for

rcalic s is 1 December 1988. Applicantsum vitae, bibliography, names of

three references, and a statement of their research inter-ests to: Mchael G. Ro ann,D nt of Biolo-ial Sdences, Purdue University,WVest Lafyette,47907. An Equal Opportunity/Affinnatve Action Employer.

IMMUNOILOGIST. Tcnure-track assiat profs-sorship available August 1989. Postdoctoral cxpenencedesirable. Teading duties involvc graduate courses inimmunology and virology and particpation in the teach-ing of a general microbiology course. Thc successfulapplicant will be expected to develop an extenaly-funded research program in area of specialty and toparticipate in an M.S. graduatc program. Send curricu-lum vitae, complete list of courses or transcrip, a briefdesciption of research interests, and three letters ofrecommndation by 21 November 1988 to: Dr. Doug-In Wartzok, Dqertment ofBfikgical Scines, I -

aun U ityrdu Univerity at Fort Wayne,Fort Wayne, IN 46805-1499. An Affirmatve ActionlEqual Oppornity Employer.

324

FACULTY POSMON INCELILMOLECULAR BIOLOGY

CARNEGIE MELLON UNIVERSITYApplications are invited for a tenure-traclk position in

the Department of Biological Sciences at Carnegie Mel-lon Unesity. Applicants must be strongly motivatedtoward carryig out research in cell an orbiology. Candidates who are just completing their post-doctoral research training will be considered for a posi-tion of stang assant professor; cptio well-qualified individuals may be considered for appointmentat a higer level. To apply, send curriculum vitae and aconcise desiption of rsearch interests (no more thanthree pages) and, in addition, have three letters ofrecommendation sent to:

Dr. Susan Henry, HeadDepartment of Biolofeal Sciences

F4ifth AvenuPittsbur, PA 15213

Deadline for applications: 15 December 1988. Came-gie Mellon University is an Equal Opportnity/AfimnativeAction Employer.

FOOD SCIENCE DEPARTMENT HEADThe Univcrsity of Arkansas, Fayeteville invites appli-

catons for this position just vacated due to r t.Ihe successful candidate should havc a doctoratc inFoodScience or a clsly related discipline, a commitment toteaching, leadeshlp ability in i t d hepiatact exramural support, a willin to degateresponsibilities, a commitment to stenint muinng andto the ficld of Food Science, and knwledge oftheuladGrant System. The Department has cight full-time facul-ty, 15 tehnial and support sta£, 30 undauate and25 graduate studnts m M.S. and Ph.D. programs.Offices, well equipped laboratories and a pilot plant arelocated togethcr in a 32,000-square-foot faclity with anew two-story wing occupied in 1985. The University isin the scenic Ozark region of northwest Arkansas, and ispart ofthe Land Grant System. Applicants should submita ktter of interest and qualifications, professional vitae,and the n a ddes, and telephone numbers of atleast three rerences by 10 Decembr 1988 to: Dr. PalR Noland, Chair, Search Cmmitte,D ofAnimal Scnces, UnivrtyofAAR 72701. The University ofArkansas isan Eqal Opport-nity/Ajlirmative Action Institution.

HUMAN GENETICISTThe Department ofMolecular Genetics, Biochemistry,

and Micobioogy is seaching or a human genctcistpartculrly an individual who is currently intcrsted ingenetic diseases effecti-ng the cardiovascular system. Theappointment is in the tenure-track and can be at any kvel.Generous space and start up monies are available. Thecurrent departm t has 26 facut and 50 graduatstudents and maintains core facilities in issue culre,DNA technolgy and transgenic micc. Lntersted appli-cants should submit their curricuhlm vitae, a short wnte-up of their anticipated research, and names of threeindividuals who are ualified to judge their abilities to:Jerr B. Lingre, Ph ., Pro&ssor and Chair,Moke-lar Geedcs, B i d ndMrbo , i-versity ofW Cincinnati ld o ne, 31 Be-thcsda Avenue, Cincnnati, H 45267-0524.The University of Cincinnat is an Equal Opportmity!

Afimative Action Employer.

MARINE INVERTEBRATE ECOLOGISTThe Deparment of Zoology, University of Florida,

invites applications for a 9-month tenure-track position,beginning August 1989, at the assistant professor level.Applicaofs research should involve the ecology ofmarineinvertebrates. The successful candidate is exrpected tomaintain a productive resarch pam, tach an upperdivision course in marine ecology, and develp a coursein his/her specialty. Applicants shouldsubmit cumculumvitac, a sucanct statement of msearch and tachinginterests, including a course oudine for marine ecology,r resentative publications, and names, addreses, andephone numbers of fourrernces by 30 November

1988 to: Dr. Frank Matro, Chair, Marine EcolgSech DofZoolg, Univer-sityofFloxida,Gainille, L32611. The Univenity ofFlorida is an Equal Opportunity/A~firmatve Action Employer.

HEAD, BIOCHEMISRY ANDMOLECULAR BIOLOGY

Applications and nominations are invited for the posi-tion of Head to establish an imnovative program nBiochemistry and Molecular Biology at Montana StateUniversity. The Head will admintresearch and teach-ing activities of eiting faculty and at least two facultywith expertise in molecular biology and biochmistry tobe hired in the next 3 years. The Program is currentlyaffiliated with the Deparmt of isr in theCollge of Letters and Science, but it will becomeautonomous soon aftcr the Head is hired. The Head willimplemnnt and coordinate an interdepartmental bio-chemistry and molcular biology program, establishteaching programs and collaborative research efforts withfaculty in other department

Qualifications: Doctoral degree in the biological orphysical scicnces, knowledge of molecular genetics, arecord of excellence in taching undergraduates andgraduates, and evidence of leadship ofan intenation-ally-recoized resarch program in molecular biologyand biodceistry required. Six years of inde tresearch exprience past the doctorate including successin procurng cxtramural flunding for odginal ch,and a record of continuous publication in rjournals are also required. Expertise in the control ofgenc cxpression in a ryotes is preferred. The successfulapplicant will show evden6cof kadership, personnelmanagement skills, innovativeness, and enthusiasm forprogram deveopment.

Salary: Negotiabl based on qualifications. Start date:On or bfoe1Jhr1989.

Applicants should submit a lctter of application ad-dressimg the required and preferred qualcations anddescribmg how they would develop an innovative bio-chemistry/molecular biology pam, a current curricu-him vitae, and three letters of recommendation to:Biochemistry and Moleclar Biolog Head SearchCommitt, Office ofthe Vice PresdentforReach,Montana State Univest, B n, MT 59717.Screening of applicants will begin on 1 December 1988and continue until asitableapplicant is hired. MSU is anEqual Opportunity/Afirmative Action Employer.

DEPARTMENT OF ECOLOGY ANDEVOLUEIONARY BIOLOGY

The Department ofEcology and Evolutionary Biologyat the University ofArizona seeks an INVESTIGATORin the analysis of complex systems of biological origin.Ares of special interest include the origin and diversifi-cation of life, including evolution at molecular andcellular levels, and the genctics and evolution oftemporaland spatial patterning in development, physiology, orbehavior in mticellular organisms. This position willprobably be filled at the junior leve. Mail curriculumvitae, statement of research plans, reprints or preprints,and armnge to have letters from atleast three refereessent to: Conrad A. Istock, Head, Deament ofEcology and Evolutionary Biology, UniveiyofAri-zona, Tucson, AZ 85721. The deadline for ais 15 December 1988, or until the posiion is fild. TheUniversity of Arizona is an Equal pounity/AjlnnativeAction Employer. Women and minwities ar encouraged toapply.

MAIACOLOGISTA maor musm with the country's second largest

collection seeks an outanding scentist, with researchinterests in terrestrial, marne, or paleontological mala-cology, for the career-track posiion, Assistant CuratorofMalacology. The candidate must have a Ph.D. and isexpectd (i) to develop a strong synthetic resarch pro-

in systematics and evolutionary biology, (ii) to beand actively involved in collec

a'ledgeat( obleof authoritative fior species diversity inthe area relevant to his/her rsearch, and (iv) to attractgrant support for his/her research program. This positionincludes opportunities for adjunct appointm at ndgraduate students at the University of Pennsylvania.Send curriculum vitae, statement of research/career

goals and names of threc references no later than 151988 to: M et Fiscr, la

Search Committee, Aamy of Naturl s ,19th and the Parkway, Phillhi PA 19103.

The Academy ofNatural Sdcenc is an Equal OpportutylAfirmative Action Employer.

SCIENCE, VOL. 242

POSITIONS OPEN POSITIONS OPEN

PROTEASE BIOCHEMISTRYThe research will emphasize the relative impor-tance ofthe various cartilage proteases, as well astheir activation and inhibition. The mechanisms bywhich the synthesis of proteases and matrix com-ponents is regulated will also be studied.

MOLECULAR BIOLOGY OF THECHONDROCYTE

This position is conceived to work in close collabo-ration with the above biochemist and other mole-cular biologists within IAA. Projects may includegene sequencing, cloning, and the use ofmolecularbiology to develop new models.

DNA BINDING PROTEINSWe are interested in the process of signal trans-duction in synoviocytes, chondrocytes. and lym-phocytes with special interest in the DNA bindingproteins mediating the differentiation eventsinduced by lymphokine/hormone stimulation.

ANIMAL MODELS OFARTHRmSANDAUTOIMMUNITYA broad knowledge of and experience with thevarious animal models of autoimmunity and/orosteoarthritis is essential. In addition, the appli-cant must have demonstrated an interest in thedevelopment of newer models and the improve-ment of existing ones.

HUMAN T CELLDIFFERENTIATION

Experience with the in vitro analysis of the inter-action of human T cells involved in the regulationofimmune responses is essential. Familiarity withthe study of T cells in autoimmune disease isdesirable.

LYMPHOCYTE ADHESIONAND HOMING

This project will investigate the mechanisms regu-lating the interaction of vascular endothelial cellswith lymphocytes. Experience with HEV biology ispreferred.

These positions offer attractive compensationcommensurate with qualifications, generousbenefits including a premiere relocation package.and an excellent opportunityfor personal growth.Publication and interaction with the academiccommunity will be encouraged. Resumes shouldbe forwvarded to: Research Director, DDW, MilesResearch Center, 400 Morgan Lane, West Haven,CT 06516.

An Equal Opportunity Employer M/F/H/V

POSITIONS OPEN

MANAGER, MEDICAL ESCH HEPATI-TIS/AIDS. Manages and exercses executive responsibil-ity for produ development group of scientists andresearch professionals in th He tits AIDS diagnosticarea. Innovates Hepatitis AIDS diagstic tStS utizingenzye immunoassay, monoclonal antibody and recom-binant DNA. Identifies and has personal responsibiliyfor innovating diagnostic tests in the AIDS Hepatitisarea for special applications, including blood bank test-ing, hematolgy secalist testing and transfusion appli-cations in international target mares. Ph.D. in humanbiolog required ogetherwith 3 years ofexperience inthe job offered or 3 years of xperience as Director,Research and Dcvelopment for Plasma Derivatives. The3 ycars ofexperience as Director, Research and Develop-ment for Plasma Derivatives must have involved manag-ing the development of new methods of purification ofplasma proteins for therapeutic use utilizing diagnostictests and biochemistry methods induding Western Blot,Enzyme Linked Immuno Sorbent Assay, monoclonalantibody and recombinant DNA proteins. Forty hoursMonday through Friday, 8 a.m. to 5 p.m., $74,984 peryear. Send resumd and Social Security Number to:Illinois Depart of Eamploymcnt Secity, 401South State Street-3 Sounh, Chicago, IL 60605,Attention: Mrs. Marie Ninean, Re nce #8156-N. An Employer paid ad.

MICROBIOLOGY/BIOLOGY INSTRUC`0R.M.S. rquired in biologial scnces, p rably in microbi-Mog.Must possess a strong backgond in immunoogy

biocdwni y, and pa g. Requirs sussfid wtachngexpriene` at atklewe levd; comm molege xpeiecprerred. Applications will be ac untl t position isilled. Transcs, letes of ro eat and/or cre-dentals are requird. Contat Peonn Off, Kirk-wood Community Collee, P.O. Boz 2068, CedarRapids, IA 52; Telehone: 319-398-5615. AJfinna-tive Action/Equal Employment Opporunity Employer.

YALE UNIVERSlTYSCHOOL OF MEDICINE

DEPARTMENNT OF HUMAN GENETICSMOLECULAR AND

CLINICAL GENETICISTThe Departm t of Human Genetics invites applica-

tions for a tenure-track faculty position in a stimulatingenvironment that indudes excellent laboratory and clin-cal facilities. This faculty appointment will be made at televel of assistant, associate, or full professor, dependingon the credentials of the successful candidate. We seek aperson with an M.D. degree in addition to a strongrecord of accomplishment in research and experience inclinical genetics. Applicants should submit curriculumvitae, reprints, and a statemcnt of research interests, andshould arrange to have three lettcrs of recommendationsent to:

Dr. Sherman M. WeissmanChairman, Faculty Search CommitteeDeprtment of'Human Genetics

YaleUniversiy School of MedicineP.O. Box 3333

New Haven, CT 06510The deadline for applications is 15 November 1988.

Yak is an Equal Opporunity Ajfirmative Action Employer.

MOLECULAR BIOLOGISTMillsaps College invites applications for an opening as

assistant/associate profcssor ofmolecular biology, Ph.D.,beginning Septeber 1989, to have primary responsibil-ity for teaching cell biology, molecular genctics, and toparticipate in teaching general introductory biologycourses. This appointment is a tenure-track position.Teaching experience is desirabk. Millsaps College seeksfaculty members with a strong commitment to the liberalarts and sciences and undergraduate teaching, and en-courages research through a strong program of facultydevelopment. Send letters of application, rdsumr, tran-scripts, and three letters ofrecommendation to: James P.McKeown, Chairman, Department of Biology, Mill-saps Colege, Jackson, MS 39210. To ensure consider-ation, application materials should be received by 1December 1988. Women and minorities are encouraged toapply.

326

MICROBIOLOGIST/MOLECULAR GENETI-CIST. Tenure-track assistant proessorship available Au-gust 1989. Postdoctoral ex ience desirable. Duties: toteach microbiology, the molecular portion ofthe geneticscourse for biology majors, to develop an externally-funded research prgram in area of spodalty, and toparticipate in an M.S. graduate program. Send curricu-lum vitac, complete list of courses or transcripts, a briefdescription of research interests and dtree letters ofrecommenation by 21 November 1988 to: Dr. Doug-lasWartzok, Deprtment ofBiological Sana UnersityPrdue Universit at Port Wayne,Fort Wayne, lN 468051499. An AJlimatdve ActionlEqual Opportunity Employer.

MOLECULAR. NEUROBIOLOGY RESEARCH.Postdoctoral research position available in molecularneurobiology to study voltag pted ion channels. Amultidisciplinc approach induding electrophysiolo,protcin purification and recombinant DNA techniqueswill be used. A highly motivated individual who iswilling to work with othe scicntists and has a back-ground in molecular biology or biochemistry is pre-ferred. Please send risustd and nanms ofthree referencesto: Dr. A. Blume, Molecular Neurobiology, cdo Mau-rem Quigly, P s Empl t Repre-sentive, Lederle Laboratories, Amercan CyanamidCompany, Pearl River, NY 10965. Equal OpportnityEmployer.

PEDIATRIC ONCOLOGIST-Medical College ofWisconsin. Applications are invited for a tenurc-trackfaculty position. The level of appointment will be com-mensurate with training and experience. The appointee isto develop an innovated research program inmpdiatriconcolog,y, immunology or molecular biology. A recordof pablications in referred journals and the ability toobtain extramural research support are essential. Ph.D.or M.D. required. Laboratory space and start-up fundsare available. Please send cumnculum vitae and the names-and addresses of throe references to: Starkey D. DavisMD., Professor and Chairman, Pedtrics, MedicalColkge of Wsconsin, P.O. Box 1997,M ,WI 53201. Equal Opportunity/AJfrmative Action EmployerM/F/H.

The Department of Psychology at the University ofCalifornia, Rivcrside, is adding a tenure-track position toits current faculy ofnineteen. Although preference is foran assistant protessor, applications will be accepted fromexceptional candidates at a higher rank. Each candidatemust have a strong commitment to exceLence in teach-

P'HYSIOLOGICAL PSYCHOLOGIST. The suc-cessful applicant will have a research program bearing ona substantive behavioral problmn using modenm neuro-biological techniqucs.

Applicants should submit curriculum vitac and re-prints and amange to have at least three letters ofrecomendation sent to the appropriate committee:

Chair-Box DPhysiological Psychologist

l vneriyofCIifonRiveide, CA 92521

UCR is an Equal Opportunity/Afirmtative Action Employ-er. Minority and fmale candidates are encouraged to apply.Application review will begin 1 December 1988.

POLICY COORDINATOR. FOR MULTILAT-ERAL DEVELOPMENT BANKS (MDB) sought byWorld Wlddlife Fund (WWF) to establish tedmicalcooperation betwecn WWF and MDBs and participatein public policy debate on MDB conservation role.Intemational experience, particularly in developingcountries, and ability to maintain effective relations withgovernment agencies are required. Competitive salaryappropriate tO U.S. nonprofit sector. By 1 November1988 send rdsumc to:

1L J. JamarWorld Wildlife Fund1250 24th Street, N.W.Washigton, D.C. 20037

PHYSICAL CHEMIST. Hamilton College is seek-ing a physical chemist for a r ementfor the1989 to 1990 academic year. All areas ofexpertise will beconsidered, but preference will be given to an expenrmen-talist. Applicants should have a strong interest m teach-ing and ch at the undergraduate leve. Teachingresponsibilities include junior lee physical chemistry,sharing responsibility for the junior leve laboratorycourse and one upper leve course in the area ofexertise.If agreeable, some supervision of senior research ispossible. Send a current curriculum vitae and transcnpts,and arrange for three letters of reonunendation to besent by 1 anuay 1988 to: Profesr Robin B. Kinnel,Department of ChemiaEty,Hamilton College, Clin-ton, NY 13323. Hamilton College is an Equal OppornnityEmployer, and women and minority candidates are encouraged toapply.

Quantitative PLANT/CROP PHYSIOLOGISTOR ECOLOGIST needed to participate in research,applying mathematical modeling of the physiology ofloblol pine trea to forest stand growth and productivi-ty. Candidate should be a U.S. citzen and have a Ph.D.with a strong background in whole-plant physiologycrop growth modelmg, and mathematics, including ditfferential equations. The position is permanent; salaryrange is $22,900 to $33,200. Position location: USDAForest Scrvice, Forcstry Sciences Laboratory, Charles-ton, South Carolina. Applicants should send curriculumvitae, work history, and names of three refrnces to:Ivor Waler, Personn Section, Soudastern For-est Experiment Station, P.O. Box 2680, Asheville,NC 28802. The Forest Service is an Equal OpportunityEmployer; women and minority candidates are encouraged toapply.

PLANT MOLECULAR BIOLOGIST, ASSIST-ANT/ASSOCIATE PROFESSOR. A tenured-trackposition to establish a research program in molecularmechanisms regulating plant resistance to insect pests.The Univcrsity ofArizona is developing a strong interdc-partmental program in plant molecular biology and thereis an opportunity to interact with thc newly establishedCcntcr for Insect Science. In addition to establishing aprominent research program, the successfil candidatewill be ex to dev op and teach a course compati-blc with thc dqxtal curriculum. Application dead-line 15 November 1988 or until filled. Interested indi-viduals should submit curriculum vitae, transcripts, state-ment ofresearch objectives, recent publications and threeletters of reference to: Dr. Brian A. Larkis, Head,De t of Plant Sciences, The University ofArizona, Tucson, AZ 85721. The University ofArizonais an Equal Employment Opportunity/Afirmative Action Em-ployer. Women and minorities are encouraged to apply.

POSTDOCTORALASSOCIATEAND EXPERI-ENCED RES CH ASSISTANT-Opportunitiesavailable to partcipate in research invohling biochemical,molecular biological and ccllular studies of roles ofrevcrsible interactions of growth promoting ligands/ginos with protein i normal mitosis and cell

proliferation in the liver. Interested candidates pleasesend r6sume to: Mary Ann Michini, Personne Depart-ment, Fox Chase Cancer Center, 7701 BurholmeAvenue, Philadphia, PA 19111. Equal OpportnityEmployer.

TWO POSTDOCTORALFELLOWSHIPS

Two postdoctoral fellowships are available for workondevelopment of a mammary cell model for expression offoreign genes. The rsearc team indudes expcriencedcell and~molecular biologists. Require demonstratedability to perform research with minimum supervision.M.D. or Ph.D. in biochemistr, molecular biology orvirology required. Experience in molecular biology isdesired but not essential. Stipend range Department ofEnergy (DOE). Send curriculum vitae and names ofreferences to: Dr. Mina Bissell and Martha Stampfer,Division of Cell and Molecular Biology, AttentionMr. Ron Lowder, Lawrence Berkeley Laboratory,Univeri of Califonia, Employment Office, 90-1012, #1 Cydotron Road, Ber%ky, CA 94720.Pleasc specify Job #A4907. An Ajirmatve Action EqualOpportunity Employer M/F/H.

SCIENCE, VOL. 242

I

POSITIONS OPEN POSITIONS OPEN

Opp inIInvestigative Dermnatology|Procter& Gamble has four entry-level openings for Ph.D. or post- Procter& Gamble is a world leader in thedoctoral scientists atourMiami Valley Laboratories in Cincinnati, research, development, manufacture, and

Ohio. Selected candidates would become members of multidisciplinary sale ofa broad range of health and beautyproject teams applying fundamental principles to the development of care products. We offer a competitive salary,skin care technology, a superb benefit package that is in the top

Biochemist or Molecular Biologist-Tmining or experi- 5% of U.S. finns, and excellent opportunities. . . . . . . . ~~~~~~~~~forpersonal and professional growth. We areence in transcription, translation, and characterization ofdermal the 18th largest U.S. corponation and ourmatrix proteins, support ofR&D reached $652 million last

Biochemist-Training and interests in the enzymatic processes year.involved in proliferation, differentiation, and keratinization. Additional Applicants mustbe U.S. citizensorpermanent

experience with histology and photobiology ofthe skin is highly residents. Send resume and publication list to:desirable. desirable. ~~~~~~~~~~~~Dr.T.J. Logan

Skin Biophysicist-Background in biophysics with ability to DrmaToLogy |develop automated characterization of biological structures. Experi- THE PROCTER& GAMBLE CO.ence in dermatological and medical instrumentation, image process- P.O. Box 398707ing, or histology would be advantageous. Cincinnati, Ohio 45239-8707

Cell Biologist-Background in cell biology with specific experi-ence in cell culture techniques involving epithelial cells, fibroblasts, Procter& Gamble isan EQUAL OPPORTUNITY employer.

growth factors, or extracellular matrix components. Supporting bio-chemistry orphysiology trainingorknowledge ofcutaneous immunologyalso desired.

DirectorMolecular Biology ProgramUniversity of Missouri-Columbia

The University of Missouri-Columbia is seeking a Director for its Program in Molecular Biology. The faculty andadministation of the Columbia campus recently established two permanentprograms, Molecular Biology and Food forthe 21s Century, which are expected to attain international prominence. The Molecular Biology Program is the focus

ofalarge interactive group ofmolecularbiologists and funds activities in four Colleges: Agriculture, Arts and Sciences,Medicine and Veteinary Medicine.

The Program funds hiring new faculty - four faculty have been hired in the last year; Recruitsand sponsors graduate trainees and postdoctoral felows - 20 individuals are currently supported;Funds core facilities for molecular technologies - DNA Synthesis, Protein Purification and Sequencing,and Monoclonal Antibody Production and Screening, each with a permanent director; Sponsorsseminars, symposia and workshops.

The Directorwill guide the developmentandexpansion oftheprogram, which willdouble in size over thenext year. TheDirector will be expected to develop ties between the University and Industry. Candidates should be internationallyrecognized scientists with vigorous and well-funded research programs, and will be appointed to the faculty of theUniversity of Missouri-Columbia at the rank of full professor in an approprate academic unit.

Nominations and applications should be submited before December 1, 1988 to:

Universityof Missouri

1839- 1989

Molecular Biology Programcdo Vice Provost for ResearchUniversity of Missouri-Columbia202 Jesse HallColumbia, Missouri 65211

qThe University ojf Missour is anaAffimtveActionlaOpputw&ity!Emp(oyer

POSITIONS OPEN

POSTDOGCr)RAL CEMsrPosdoctoli availabk immediate for syn-

dteicstudies of and inorganic chemica that arem unstab about 100C. A soLid b r in

organc synthesis is essentiaL Prvious witsynthesis of nitr~u~ and/or sufuir aii -pounds preferred. curriculmite adtnd names

n o Bakery boxato Em-k 0 ~~90-1012, (Spoe lbo91),

Bq, CA 94720. An Equd Op0atit Em,oyerM/F/H.

POSTDOC1ORAL FELLOWSEHP INLUNG CANCER BIOLOGY

NATIONAL CANCER INSTrrUTE-NAVYMDICAL ONCOLOGY BRANCH

Applications ar invited for three di nt pos r-al positions. One otm e s des of g

fimtoneal assays and abWudi e stry. A second posit iontrization of ptide hmne growth faco prducedby hmg cancer cel lines and qures a bakound inanaytical b tr. he final ption is in the arof peptide gmth ft q t nd back-grund in analal t iques cding chm a-phy raio a . Positons are available im-mediatdy and would be 3-year appointmnts.Send curicuhim andthree rf to: Dr.

Janes Musin, NCI-N MedialBranch,B Naval Hoqital, Beda,20814. An Ajlive Acdion/Equal Oppq Emploer.

POSTDOCTORAL POSITION available immedi-ately to undertk research i lip meboism/atherosderosis at Sinai Hospita ofDtroit. ITh successfil candite will be ce to study the regultion oflipoprotein metabolism by spcfcrcpo-iadinter-actions on human culrurd cels. The postion rires aPh.D. in bio / cr bio and kOf tissue culure tand protin isolon. Scnd uricum vte and amesof three referene to: Director, Center for Cardioa-clar Reseach, Sinai Hospital ofDe:toit, 6767 WestOuter Drive, Detroit, MI 48235. Sin Hospisl isapiated wi Wayne Stae University and is an Equl Oppor-tnily Employer.

POSTDOCTORAL POSITION-A posoralposn in biochmisry is availabklethe photoaffinity labeling and sequecng of'aLosticand calytic binding sites with emphasis on the 2-5AsyntheraseIRNase L systoemin normaladcells.Fui is available for at least 2 years. Applicantsshould submit rums and names and addrs ofthreeences to: Dr. Robert J. Suhadolnik,D t

ofBioch, n T~emple University School oMcdi-dne, PA 19140. An Equa oppotmity/Ajinnadve Acion Employer.

POSTDOCrORAL POSMON available immedi-ately to study mulidrug reistance in human tuneors.Project will involve cukuringofntmor cells, flowsorting,iimunological and molcular assays. Expeienceintissecultue andconcual background in mollar biolgyare essential. Salary commensurte with expene. Sendcurriculum vitae and names of thr ce to: Dr.Ior Roins, Der of Genetis, UnivesiofMinois atCh , 808 South Wood Stet, Chica-go, IL 60612. An Equal Opportuniy/Amadive AdiosEmployer.

POSDOCTORAL POSMON-A posdoctoralposition in biohmnistryisaailable mmeiately t stucythe enzymoko:and molcular biology ofdouble strn-cd RNA as teda to the mechanism of regulation ofHIV-1 and HHV-6 replication and control ofcancer celVrowth in humans and in culture. Project will includeidentification and sequencing of the dsRNA receptor.Funding is available for at kast 2 years. Applicantsshould submit r6sum6s and names and addresscs of thrcerefrences to: Dr. Robert J. donk,D tofBiodit, Tcmple Univesity School ofModi-anc, Phibdd~, PAS 19140. An Equal Opportityl

Ajinnative Adion Employer.

328

POSITIONS OPEN

POSrDOCrORALPOSMTION avaibblb 1 Januay1989 for sudies of gene ntductio and staity inaillus themopik s uin pon Tn916. Bak-

ground in microbial genetic prefcr redw Send criuuvita and lte ofren to:-

Dr. Pabc OriD _ofMk_ib and Pubic Hed&

OCITORAL POSTIMONPh.D. d i tissue cature required for devel-

omnoftsumodel for idnrited mektaboli disease.uires or_d_e opnoavarietyofskilla4 i,i x d u~~~~~~~meel-

reconsited ane ame. Pi is -ly funded. Star innedily. Contact: Dr. Gar J.Murray, 10, Room 3D04, Natosu Iti-

ts of H,MD 20892

A POSTDOCIORAL POSTION is availablei

p~studiesOfgee reagation by sidPM11!rotendal~ ~ ~ ndmuaencanl

yse of structure4uniction rltosisfrhmnestro.~eartd rone rcecao clnin and drchat-

ation or genonic DNAs ibr these protenms, alysis ofvitae, statemetofinterests,andtm elof rece

to:Dr.eoffreyLGess h U rirsiyofCcalittt-oli2s 5841E widiMbiar-

DNAwih ex n Is aellua re with tod

snails. B scould behdpfr S di

videnusrosopial nalsisof ehaiormoulaionofgmembrane exitability rsnapti efccyo netorkn- dofn urnlpaten geeration. Sendcriuu

vtereeee,adsamenthofi itre afr.fAcEa:Dr.Gpoviy ILG/Afss TheUAwmpl ofyerg, Bc ayhsb B_ 2, 584I SuhMrlEdAvw Chca IL 60637.

POSDOCORAL POSiTION:RabortPh.D.wiilpaincem I dhbr g wed t

study in b lmctoandnm snilc apoas.Excpne nr

nantDNA_ techniqus saly of bSaary:,$m240Sefneuor ;oarSi

rsa rerer terstoa Dr Rso: DI.onDom Murp o ofh tr iesi of &Kn-

UniS;eaXgo,L~~~6067.

EalOpprsmt/Afmudv Ado Emlyr

POSTDOCTORAL POSMTION avaibbkler upato3 yin an o-i studydofa nelmetaboif pathwaypathwayin an uulacdtguionofheam mo as yesst fidcfi iod uus.MML-arm nd,b geeatpresnitric oxideasre mmitmei-nm

7N, xs il4,000. Send

D_ of 2_, Uq oParticipatiOncu Kb ioo36no oft r nypfc On,chmiclyAlcactez Ato oeinemPOSTDOC RA POSMON a mibbkk t

ipate in gm on wnDg su Ofa nw kpWEwv

Nad. Acad. Sa. U.S.A. 8i, 6369 (19872] Tipathvay invle an unusual oaddai ofthe iL-e a~~~~~nit, xwe as an _m IP

PaYcipoho d beany one of*mareas: %a"ymed---trni ofdreii

ates, or celluar role of dte pathway. Some rntis n and mit ind: protein purifi-

cation ,enbymoiogy' dchemisy or cell utuetoeniques. Plase send a ru vite and the namesoft rerfereAcesto:Dr.MichaelA.Maretta,(f7Iu428Ch.¶&&ret, Y f -igsn, ~AGbr48109-1065.

A Nondiscn , Ajlsaive Adion Emiplor.

POSTDOCTORAL POSIMONIN VrO TOXICOLOGY

Immediate opening or an indiidual within mammaln cllcture to stuy the bmechanisms of acute and chronic toiies of cadmiumand odtr selted mends. Send cufriulum vitae andnames of three references to: Dr. Zahi A. ShalkDqetmnt ofPharma andT y, Uni-vasity ofRho Island RI 0288

POSITIONS OPEN

PC01DOC1OR LPOSrrION avaiabe1 anuaybt of o miatd s will include: i n2umn-

bn iok umpahanythe l dhe breiperise.Send currum andw suenc:s ~~Smd cur-hlm md nes of od to.- Dr. L

Box #7545 MacNidee

21201. Ajkm_v C 1 ky.

POSMCOALPOSMION nU I Juayuof 9 spi iiurr. Fdbow wi~~~~~~ c B f (Dqu ze_,-Ne

7 ThUfmd),uu. andEqe: l

Oppoufk Aio EploEyrfFwda) wi inde mmbsi6Wrhuity sin* uni !Cmd I =-o

bard Send -bm d eleofoo:r6mw Dr. i D OfP

*l||ss#75S."|dti NC

Qppww*Apiwve Ad Mh.

POSIDOCIORAL POSITIONINBI -CAL PHARMACOIOGY for rcet Ph.D. intrstedin dt biocdmical lation of ntancerg activi-ty. Reserchon theueofnuckosde tanspotiOD incasettht SelCtiqt f b hu-nm rs wowincu uroras up inmiWary S220I0 OD ft5, . %nd dm vit andfur ktt of Mr ----mint: hdIR & BdMD, D w of celPhar

derdl P.O. Bo 318,M TN 38101.An Equal p A Adio Eployr.

POSrDOCTORAL POSiIIONIN VASCULAR CELL BIOLOGY

Ibis positon is in an i y rupwreerh kcvis inariknsi -

ogy , candltdatsd Studies e anemphasis on mechanical stress dircts on vasar endo-thea ad smooth musce cells. Q inchde aPh.D. and the a tin ancl aheb S dze netiabl Send curricum viae andnmes andadr ofdee refrences to: Dr. Robert AL Nerem, B i-

2768 GA 30Tec . Tau2768. GCrg Tec is m Equ0diQy

POSIDOCT0RAL, POSITIONINSULIN ACTION

Available 1 March 1989 to study insulin resista inpary da and of iulinact on tiesis g e s nd po-gcnl e,ondineofresearch oalso,kasoffeence, and pints : Dr. Stphen Mar-sall,Unr ofnessnfMemph,DetofBiohemistry, 00MaMdnAven,MhTN38163.

POSTDOCTORAL POSITIONSAvailable January 1989 to sxty the stucte ad

recommendan t: ilm2+tionsto:a,

Unierstyofoow

ThUibiok a iaE al psiUty/AjlraveaPh.D. and a stAd Employerbio.ph i or p .kOf

anmd two kem olf

Dr.enP.UninuqoIu

Iowa Ciq, ]I.qandX7hc Wnvasity ofloum is m Eqsl Opp/XtyAkvc

Acdio Enpo -w.

SCIENCE, VOL. 242

Opportnities in AIDS Related Research

Basic Research and Drug Discovery

_ A offmann-La Roche, a research-intensivepharmaceutical company, and Roche Insti-tute of Molecular Bilogy, its basic research

insfitute, are seeking p_eIlehl hubm to join amultdisciplinary team engaged in AIDS related research.These positons are supported by a grant from the NIIDNO" C_eIpmlve Dlwseey Gimp For The Ia-mea Of AIDS. The program leaders are: Dr. Ming-Chu Hsu(Roche Exploratory Research), Dr. Craig Rosen (Roche In-stitute of Molecular Biology), Dr. Robert G. Roeder (TheRockefeller University) and Dr. David J. Volsky (St.Luke's/Roosevelt Hospital, Columbia University). Suc-cessful candidates will have the opportunity to carry outbasic rsearch while interacting with colleagues skilled intranslating relevant findings into therpeutc approaches. Inaddition, these positons will offer opportunits for exten-sive collaborative interactions wifth scientists at theRockefeller University and Columbia University in the areaof regulation of viral gene expression. Publication of basicresearch findings is encouraged.

Molecular BiologySeveral positions are avaUable for PhD molecular biologiststo conduct studies on the regulations of gene expression ofhuman immunodeficiency virus. Familiarity with recombi-nant DNA technology is essental and experience in theareas of transcription factors, protein puriflcation, protein-DNA interaction and microbial genetics (yeast and bacteria)is desirable.

Structural ChemistryPositions are available for PhD chemists to investigate the

three-dimensional structures and ligand-binding attributesof HIV proteins via NMR spectroscopy and crystalography.Facilities include a dedicated VXR-500-S spectrometer, aRigaku AFC-5 system wifth twin Xuong-Hamlin area detec-tors, a VAX-80 computer, and an E&S graphics sysWm.These positions offer close interactions with our molecularmodeling group. Applicants should be experienced in two-dimensional protein NMR or protein crystallography.

These positions offer a stimulafing research environ-ment, comptitie stipends, and exclent benefits. We areconveniently located 12 miles from New York City. In-terested individuais shouid send curriculum vitae, a briefsummary of research interest and career goals, and namesof three rfrences, to: 1k MIagC Ha, I dO _dey sa Vrm_y, Rke s340Kh_eud kam Net Now Jeel WM1 We are anequal opportunity employer.

Working Today For A Healthier Tomorrow.

Senior HPLCBiochem Specialist

DIONEX Corporadon Is one of the world's leaders Inchromatography and recognized for Its superiority Inblocompatible systems, carbohydrate analysis technol-ogy and Ion exchange chromatography. Openings existfor three PhD Biochemists (one position In Sunnyvale,CA, one In Soudem NJ and one In Chicago, IL). TheIdeal candidate will have a broad background In chroma-tography, preferably with strong emphasis In blochemis-try (carbohydrate and protein experience desirable).Expertence In pharmaceutical analysis and/or glywcopro-tein or peptfde mapping techniques would also beadvantageous.The ability to give high quality technical presentations,research existing as well as flnding new marketingopportunities, and good technical skills with experienceIn developing Innovative, analtcal techniques arerequired. This person must be highly motivated and aself starter with the ability to work well with people.Travel 20-3096 of the time required.DioneX offers excellent growth opportunlftes and acomplete beneflts package. Please send a resume to:DioneX Corp., 501 Mercury Dr., Sunnyvale, CA 94086or call Maureen Sheehan at (406) 73740700 x426. Weare an equal opportunity employer n/h/f/v.

DIONEX

jj11 i A BETTER SOLUTIONLAJL n. IA -J- l-AEL ~~- ~

II

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCT

INFORMATION SERVICE PUT YOU IN

TOUCH WITH THE VENDORS WHOSE

PRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATING

THE SPECIFICS ABOUT YOUR PROPOSED

LAB AND WE WILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1515 BROADWAYNEW YORK, N.Y. 10036

I III

POSITIONS OPEN

POSTDOCTORAL POSTIIONS-gene cxpres-sion and signal transduction. Positions avaiable to studyregulation of gene expression of G-proteins and G-proein-ked receptors [P.N.A.S. 85, 5021-5025(1988)] cell and molecular biology techniques cmpha-sixed-incding high-resolution indirect immunofluores-cence and site-directd mutagenesis. Send curriculumvitae to: Dr. Craig C. Malbon, Detment of Phar-macology, School of Mediine, State Un rsity ofNew York at Stony Brook, Stony Brook, Long Is-land, NY 11794-8651.

POSTDOCTORAL RESEARCH POSMON-P position in the molecular cell biolo-

gy of clathrin coatedmiembranes. Focus is on the regula-tion of coat assembly in cclls and on coat-membranereceptor interactions n endocytosis. Expericnce in pro-tcin chemistry or molecular bioklgy preferred but notrequired. Send curriculum vitae and names of threcrerences to: Dr. James I- Keen, Fels Institute forCancer Research and Molcular Biolog, TempleUniversity School of M ic Philalhia, PA19140. An Equal Opportunity/AJfirmative Action Employer.

POSTDOCTORAL RESEARCH ASSOCIATESPositions through the Nitrogen Availability Program

at Michigan Statc Univcrsity. The Program is direct-bytwelve faculty in Departments of Biochemistry, Botany/Plant Pathology, Chemistry, Crop/Soil Sciences, Genet-ics, Microbiology, andMS -DO, Plant Rcsearch Labo-ratory. Thc program fosters innovative interdisciplinaryrcesarch emphasizing biotcchnological approaches tonitrogen availability to plants: biological mtrogen fixa-non, denitrification and ureolysis. Starting salaries:$18,000 or higher, depcnding on cxperience, plus bene-fits. Candidates with strong potential for basic researchand degrees/experience in molecular or cellular biologyor the disciplines above should contact: Dr. KennethNad&r, NAP Director, Botany/Plant Pathology Dr-partment, Michigan State University, East Lansing,M 48824. Tepone: 517-353-5167.MSU is an Ajlrmative Action/Equal Opportunity

Employer.

POSTDOCTORAL RESEARCH on the Effect ofMutations at an Enzyme Active Site on Function. Aposition is availabk for a candidate with research experi-ence in enzymology or biophysical chemistry to join aresearchgroup actve in this area [soeJ. Biol. Chem. 263,9187 and 10304 (1988)]. Training will be provided inmethods for s ligand bin g, cnimuionalequilibria and catalysis, include methods for the study oftransient state kinetics. Starting salary $22,000 or higherdepending on rclevant experience. To appy send curncu-lum vitae and thr refernces to: Dr. IL L. Blakly,Dep no£Biocemical and Clinical Pharmacolo-, St. Jude Childs Research Hospital, 332 Northauderdale, Memphis, TN 38101. An Equal Opportuni-

ty Employer.

POSTDOCTORAL RESEARCH ASSOCIATE-Immediate openig for postdoctoral research associate towork on DNA Damage and DNA Repair. Back&roundin biochemistry or molecular biology. Send curiacumvitae to: Dr. Nahum J. Duker,D rent of Pathol-ogy, Temple University Meal Sol, 3400 NorthBroad Street, Phildlphia, PA 19140. An Equal Op-portunity/Ajlrmlative Action Employer.

POSTDOCTORAL RESEARCH POSMONMOLECULAR MECHANISMS OF

MAMMALIAN CELL GROWTH CONTROLMAYO CLINIC/MAYO FOUNDATION

Postdoctoral position available 1 January 1989 tostudy the molecular and cellular biology of peptidegrowth factors. Specific areas of research include theidentification and cloning of growth factor-regulatedgenes and the delineation of spedfic protein-DNA inter-actions involved in transcriptonal control. Applicantsshould possess a strong baound in one or more ofthe following areas: recombinant DNA methodologyprotein biochemistry; mammalian cell culture tech-niques. Send curriculum vitae and three references to:Dr. Michael J. Getz, Department ofBiochemistry andMolecular Biokoy, Mayo Clinic/Mayo Fountion,Rochter,MN 5905. An Equl Opportunity/AjfirmativeAction Institution.

PROTEIN BIOCHEMISTPitman-Moore, Inc., a leading animal health company, has achallenging opportunity for a Protein Biochemist with ex-perience in protein primary structure analysis.The successful candidate will have a Ph.D. in proteinbiochemistry and a proven track record in amino and carboxyterminal sequence analysis, tryptic peptide mapping andamino acid analysis. He/she will lead a group of four otherscientists who are responsible for developing strategies forverifying the primary structure of proteins produced byrecombinant DNA technology. This includes the developmentof methods for identifying the structure basis ofchromatographic variants and for verifying protein modifica-tions. Prior supervisory experience is essential, as are ex-cellent written and verbal communication skills.As a member of the Bioanalytical Research Section, the in-dividual will join a dynamic research group that is solving pro-blems related to biotechnology, drug delivery, and new pro-duct development.Salary will be commensurate with experience and includes acomplete benefits package. Please send resume and list ofpublications in confidence to:

Mr. M.G. RayPHman-Moore, Inc.

P.O. Box 207Terre Haute, IN 47808

An Equal Opportunity/Affirmative Action Employer

POSTDOCTORAL RESEARCH POSMONavailable to study the role of polyunsaturated ftty acidsin immurioinfammatory phenomena, particularly thcsalutary cffect ofessential fatty acid deciency on fkmwx-ulonephritis and renal transplants. Experienc m lipidbiochemistry or immunology desirabk. Salary compcei-tive and commensurate with experience. Send curriculumvitac and names of hree rrences to: James B.Leiowith, M.D., Departnt ofPharmacology, Box8103, Wa i School of Medicne,660 South Eulid Avenue, St. Louis, MO 63110.

POSIDOCrORAL RESEARCH POSMON isavailable immcdiatcly for a biochemist/molecular biolo-gtotOpacte in studies of two important human6bodLuing proteins, plasmineogn activator inhibitor-

1 (PMI-i), and von Willebrand factor (vWF). Currentwork is focusse on (i) nwm cular structure/functionstudies for both p ns; (ii) ration of PAI-1 genecxprcssion; and (iii) the molecular basis of von Willc-brand's Dises. Please send a description of rsearchintcrests, curriculum vitae, and names and telephonenumbcrs of three references to: Dr. David Ginsb,Howard Hughes Medical Insttute, 1150 Wes Med-cal Center Drive, 4520MSRB I, Univeity ofMichi-gan, Ann Arbor, MI 48109-0650. Equal OpportnityEmployer.

POSTDOCTORAL TRAIING-CELL MA-TRIX BIOLOGY. Postdocoral positions are availablein the area of cell biology of celex lla matrixintcractions. Applicants should have a recent Ph.D. inccll biology or a related field. Projects include (i) efi;ctsof proteogycans and non-enzymatic gycosylation onvascular cell-basement membrane signaling as molcularmodes of ather osis and diaes, (ii) molecularnechanisms controlling matrix architecture and (iii) cell-matrx interactions i morphogenesis. Send curriculumvitae and names and addrcsses of references to: Drs.David E. Birk and Peter D. Yurchenco, Departmentof Pathology, University of Medicine and Dentstryof New Jersey-Robert Wood Johnson MedicalSchool, 675 Hoes Lane, Pisctaway, NJ 08854-5635. The UMDNJ is an AJfirmative Action/Equal Employ-ment Opportunity Employer. M/F/H/V.

FaculyPostom

The Department of Biological Chemistry is making a majorcommitment in the general area of molecular biophysics and structuralbiology. Applications and nominations are invited for six new facultypositions, three to be filled this year, with the remaining three to be filled inthe next successive two years. All six positions will be either tenured ortenure-track 12-month appointments, with the initial three at any levelfrom Assistant to Full Professor. Space, start-up funds, and salary areextremely competitive.

Successful candidates will be responsible for developing independentresearch programs and teaching in their discipline. Applicants whoutilize X-ray crystallography, spectroscopic methods including 2-dimensional NMR, and modeling are particularly sought.

The ten current faculty members within the Department representresearch interests in molecular genetics, enzymology, carbohydrate andlipid biochemistry, and protein folding. The Department also participatesactively in several interdepartmental programs including those in Cell andMolecular Biology, Neurosciences, and the MD/PhD program.

The deadline for receipt of this year's applications is 1 December1988. Interested individuals holding the Ph.D. degree with appropriateexperience are invited to apply by sending their curriculum vitae, a shortdescription of future research interests, and the names of three referencesto:

SachbeS/o Dr. George Roe, Chairmanepertmento 'lowogcChemlsary

The MitonS.HersheyMedicalCentwrP..BoxS50C

Herobey,PA 17083

Penn State is an equal opportunity/affirmative action employer.

SCIENCE, VOL. 242330

POSITIONS OPEN POSITIONS OPEN

IMMUNOCHEMICALSPRODUCTMANAGER

SIGMA CHEMICALCOMPANY manufactures and dis-tributes reagents for research and diagnostic use to an inter-national market that relies upon our service and productquality backed by the integrity and professionalism ofouremploy At its St. Louis headquarters, hundreds of staffpersonnel are involved in the development, manufacture,quality control, sales and marketing of more than 22,000products.

An excellent opportunity exists at Sigma for an Immuno-chemicals Product Manager. The successful candidate will beinvolved with the development and implementation of salesand marketing programs for Sigma immunochemical reagents.Minimum requirements are a MS degree in a biological sciencewith advanced training in immunology. Additional training inone or more of the following areas preferred: ImmunoassayDevelopment Production and Characterization of MonoclonalAntibodies, Cell Surface Marker Assays, Immunohistology andProtein Purification. Demonstrated experience in the sales andmarketing of research or clinical products a plus. This positionrequires a self-starter with good people and communicationskills, a positive attitude and the ability to tum a plan intoaction.

Sigma can provide a competitive salary and a full company-pai benefits package. Send our resume and salary history to:ftnsminmsl Man (CAMI , SIGMACHEMICALCOMPANY, .O Bo 1450, St. Loi, MO 63178.

An EqualOppommt Empoyer

CHEMICAL COMPANY -

ERI. Inc. is an Equal Opportunity Employer

MITWhitaker College of

Health Science and Technology

POST-DOCTORAL SCIENTISTS

Several positions are available for the study ofgenetic change in humans and human cells.Development and application of technology to

observe mutational spectra in human blood andtissue DNA are emphasized. Both epidemiologicand mechanistic studies are possible.

Salary: $25,000 per annum for entry-levelcandidates.

Please send resume to:Prof. Wiflau G.1Thify andDr. Phoutome Keoavong

MIT, Room E1S-677 Massachusetts Ave.Cambridge, MA 02139

Telephone: (617) 25346221

MIT is an equal opportunity/affirmative action employer.

THE

SCiENCERECRUITMENT

"FOUR DAY CLOSE"NOW YOU CAN SEE YOUR AD IN SCIENCE

FOUR DAYS AFTER SUBMISSIONScit Recruiters can now averte ps alm assoon as Fe need arises. Intedofr space a monft ormore in advance, you can now place your ad four days beforethe magazine mailing date. SCIENCEis mailed on the coverdae.

Film (right-reading, emulsion face down) or full camera ready

art and inserton order must reach: SdENCE, Short Close Desk,1515 Broadway, New York, NY 10036 by NOON Mondays(except for lgal holidays when mateial must reach New Yorkby Noon Fridays). Beause space is limitd, the four-day cosepage will be sed on a first-come, first-served basis, at a15% premum. 1/4 and 1/2 page ads only.Now you don't have to wait to find the Ws you need

immediately, nor must you d ise n a Sunday paper that

pans a lot of sand, but not much gold. Scetif

know Fat SCiENCE ads fl the job betr. Now ey fill it faster

too.You can call it "INSTANT RECRUITMENT."For furher infrmaton, e Ed. Keler, Re t Ad-

verigMaar, or Donna Rivera, Prod nM r atSCiENCE: 212-730-1050, or wrte to: SCiENCE, 1515 Br ,

NY, NY 10036.CURRENT DISTRIBUTION 160,000

ERICANCER BIO ST / RESEAFCH

SCIENTIST (Ph.D.)

The growth of our research consulting firm has createdan excellent opportunity for a CANCER BKlOGIST. to joina group of scientists in the design of experimental studies.in the preparation of literature reviews and in the conductof health-risk assessments. The ideal candidate will possess

a Ph.D. with 0-3 years postdoctoral experience in the cell

and tissue biology of cancer (e.g. tumor promoters. growthfactors. mutagenesis). Excellent analytical and communica-tion skills are a must.

ERI is a rapidly-growing environmental research and

information consulting firm. with offices in New York City.Watertown (Mass.) and Palo Alto (Calif.). We offer qualifiedcandidates a challenging and rewarding work environment.

top salaries commensurate with experience. and a full

benefits package. This opening is at the New York Cityoffice. Please send Resume to:

Dr. VWfwn H. BaieyErwirementa Research konnatlon, Inc.

575 Bghh AnueNew York, N.Y. 10018 3011

I

j

C\ //)

-. '.

POSITIONS OPEN

PRESIDE;NTGEORGIA STATE UNIVEBSITY

The Boad of ReIe of the Ulniverity System ofGeorgia announces its search fr a new Pesident atGoorgia State University to take office on 1 July 1989.Candidates should haadist i record ot accom-plisin inteng, and adminis inhsigh education or execuive-lve anda w ing knowede of hghe education. A dorateorrpriate rennal dere is deirale Nomntin

siou ithe I m currentaddrcss. Applica-tions should indude a letter of interest, cu l mand the names and addrsses of five persons who canserve as references. Nomiation and appliions shouldbe received by 18 Novembr 1988 to be assured of

All n.omnas and cions houldbe add to: Dr. HL Dean Proe, Chan lUnmiys ,ofG 244 Washin

GCorga StA Unvy is an Equal ppotity, AfJnn-five Action Employer, and is a unt ofthe University Systen ofGa.

The Departmn ofPadhl and Laoatory Medi-cine, of Texas dal Sool at Hous-ton, is seing diat for thec pOsitio OfPROFBSSOIND Ofothe eaThe succssful candidate will have a medial degee(M.D. or equival). The candidate should have admin.istrativ p to iveleadcrshi is mutifaeteddepartment. Th cnIdate should be abk to build upmand f strengt the significant resarch base al-ready established and strengthn the clinical serviceaspects of the dea nt.Te deartn s maoraching the

graduat scdol of biomedical sciences. tOcustomary mda tching, the depa t is cedwithe teacU n--- .or nomi-natos should adde dt o:JM .MD,PhD, airman Seua Comm Mie, C/o De -met of Pediatrics, Ibe Univ ofTca MedicaSchod lt Houston, P.O. Bx 20708, Hoon, TX77225. Deadline for applitions is 15 November 1988.The Unvei of Tais an Equl Oppotn Emplyand specialy invits and e wuapaions mo womenand mfint.

PROFESSOR AND DIRECTOR OF ASSO-CIATE PROFESSOR AND DIRECTOR, Divisionof Health Services Admini . Qu : M.D.or Ph.D.; e in h a tion, re-search and t publications in craii-caly r j a, active membership in schol-arysocties. Responsibilities: teaching, researh curric-ulum e ens, s in of m da tnts,

d quaioniaions. Salay?Xilae 1 May 1989.Applicatios deadline: 1 December 1988. To: Chair-

man, Department_of Preventive Mfedicie and Bio-metrics, do Dir r, Civilia Peso , UniformedServic Univeiy ofthe Healh Science,MD 20814-4799.

Thw niveity is n quad Opp0orty Employer.

RADIATION BIOLOGISTOak Ridge Naional Laboatoys (ORNL) Biolgy

Division is seeking applicants with a Ph.D. or equivalenin radiatim biology with a research emphasis on the

hanisms ofinductionofcancr. Persons with xperi-aen in moleular biology, biog, orrdeatd discile are en a o r nd Te suc-cessfil app will be xpeced to dvep ir own

as wel aS c e in projes of theRadiatio CarcinogencuPrgrmORNL ofiers an ecellnt b ts package and a

gnccums-oa mphand

uonract cP. 2009,rate Rk NIabrm, Oak TNI 37831-077.

ORNL Operat by Martin Mariettafor the

U.S. Dqwatent ofEnegyAn Equal Opporunity Employer

U.S. Citizenhi/Pennanent Resident Required

POSITIONS OPEN

The Deartmnt of Neuroscieces, School of Medi-cne, Univery of Califomia, San Diego is sqplifiedes (Ph.D. in biochemist or molculr

biology for one POSTGRADUATE RE ARCH position tO work in a labratory of human biom lgenetics, available immdiately Pso requies back-ground in (i) and protein chnmstry, or (ii)nioular biolgy. Salry is based upon pubLished Uni-vr of Calionia say scheduk. Send curriculumviae and names of three reerees to: Profeor John S.OBricn,D ofNaocinces, Unversity ofCalurna, San Diego, Mail Code M-034, LA Jola,CA 92093. Appi will be a d ugh 1March 1989. T Univy ofC i is n EqudOppomitylAjlnnve Acion Employer.

PROFESSOR OF PATHOLOGYDIVISION OF IMMUNOLOGY

The Detmcnt of Pathology at The Univrsity ofIowa Coleg of Medicie is cptngap firdhe poson of Pessor in dte sub ara ofImmunology with emphasis in imm aaumommunty. Exprienmce transgc d y-bridcn teholg necessry. Succsfl candidatelicensure inshouldhaveM.D. and clible for L;e inthD Statd of Iowa . degreem ppopriated-pliThe appicat shld have a r d atsacry

s commensurate with cn Leters of app tion should be dircted to: Richard G.LInch, M.D., Professor and Head, De t ofPahoky, heAUniv of Iowa Clleg ofMCi-c, Iowa Ciy, IA 5 The UniversItyof owa is anAfintie Aatioqual Oppo ity Employ.

REPRODUCTIVE ENDOCRINOLOGIST:The Department of OB/Gyn, Univerity of KansasSchool of Mediine-Wichita ines applicants for twor rch po in the Women's Resarch Insitte.Qualified cndidates must hold a Ph.D. or M.D. andpostdoctoral r an be capab of establishing an

__ro. geia in reprouct endocri-eobrrc dbagy o a"p. Ibne 1cmsid w jo cicadacd whosccb interes incude in vitro n, gmete

physiolo¶ teticuarand a

± iftaec satement ofnu,andens of threfrences by 1

January 1989 to: Dr. Brook A. Kel, Ph.D, SdentficDirecth, Che Women's Researh Intiute, Univers-t of X_aa School ofMediIneWihit, 2903 Eastc , Wchit, KS 67214. An Equd OpnitylAflnaiv Action Employa. Applica are soughtfiom allquldiied peoplk regrd ofrmce, rdigion, color, sex, dability,vetrn stas, nad origin, age, or ancesry.

RESEARCH ASSISTANT PROFESSOR (M.D.,Ph.D., M.DJPh.D.) withe in molecular biolo-gy of the human immune response system. Please for-ward curiculum vitae to: Dr. Sh Mn Ful, Univestof Virinia Diviso of Rhemal , Bo 412

ChrlttsIlle-"21, VA 22908. Tlep . 804-9245213.

RESERCH ASSOC E positio Ph.D. inmmuoudoff or biochemistry. Duties involv digning and con-iductin research m: odllar t m c enum phagea pro-

ton _rparatmn decmisrr and innu-nochmny. Starting salary is $17,400, based on a 40-hour week. IfnotaU. citizen, please idicate visa sta.'Apply to: E 16- 91 D _ N-277AL :CFob OderN~i,er NC8103I49, D Cod 9.227410. Afirm

ative AcioEqua Oppony Employer.

RESEARCH ASSOCIATESTwo research positions are avilabl immediatey for

Ph.D. with expeence in rduve -or-

ular bi . Wo in vitro fila ninanimals, protein biochemiry and rcombinant DNAtechnology. Send curculum vitae to: Dr. Rajesh NaT,Department of Obste s ad Gyneogy, MtEinstn Colege of Me , 1300Mrris ParAvene, Bron, NY 10461. T -el e: 212430-2225.

POSITIONS OPEN

RESEARCH ASSOCIATE needed by Neurophysi-ology Laboratory in the Department of NeurolgyColumbia Univsity College of Physicians and Sur-gons, for studies ofcpikpsy and human motor controLApplicnts must have cxpence with desi and imple-mentation of de arcuitrymvn biologalsignal acquisiton, capability for compuserpand ineringnd nd basic knowkdg of biolgy andphy gy. E and/or computer bakoundan advantage Ability to interact widt pai nts and hmn subjects required. Write to: Dr. A. Ped-Iqy, TheN l Iti 710 Wes 168thStreet, New York, NY 10032. Columbia University takesAfirmative Acton to ese Equal Opporunty.

RESEARCH ASSOCIATE psitoniS availabl inthe Deprmt ofBiocheisy r a Ph.D. with somepostdotoral research e r . Utiing chsuch as tissuefictionaon, chrandhOtOi?ic tracer studies, the s a i tcwill con-

duct kende t research on the distribation, biosyn-ofpolyisopoid akohols intr-

mediam in gly pro bimnicesis. Salay $25,000 to$30,000 phis Send curricuhm vitae, fist of

and names of thre refrees to: Marth

eOsWter OntaiO, LAndo,Ontario, Canada N6A 5B8. In acodawith Canadialinngin requirnens this adverseme direed to Ca-

di citizxes and pema rsides of Can. An EqulOppos4 Employer.

RESEARCH ASSOCIATE who will purify plsmamembranes b UlUtio na iom uman whiteblood cedls elon and isolatemembrane proteins by detrgent e raction and column

of cdimstwoinalpolyacrylaMide gel

,

ectrpho westen blot analysisand thin layer chromaohy of dcelular lipids. Prepareposm onu imbrane fr s and masure

the bioogl ives in cdlularpoferaion and cdlu-lar qt y tissue culture bos Evaluate themmrnogicaf response ofliposomeprotn compexfor d of qsyndFtc vaccines. Per inimal

dithe dctiven of liposome-prooeinomplexes for the control oftumor growth and metasa-

sis. Ph.D. Dgee in or biochmit with2 years of research raining M$25,300 annual salry. t: erasCommissio Ho o, Texas or send to: Tel-a8B C i, P ~~~~Uni,As

tin, 178778.7J.0. #5515202. Ad Paidfr by dn Equdapoyment OppotityE mloyeff.

RESEARCHASSOCIATE iton available imme-diatly to st*u intereation of t-pat ic humanmycoplasmas. Qualifications i a rent Ph.D. iniungyor rebted field, enoc in protein purifi-cation, m m S ofmonoclonal antibody and somprhivenbk nd inrecombinant DNA tenl. Sd a teand three rrences to: ML CoeVa, Ph.D,Arthr Int te, 2455 Army Navy Driv, Arlinton, VA 22206. Equal Opporunity Employer.

RESARCH ENVIRONMENTALIST-TheSoudt Florida WaterM District is seekng awetand axos with 1s in plantembjw ianntitqig.Mnmii are aBaEisdegree in logy or eol andov2 years ofreson-sible expeience g re-search; or an al comb of aining andexperience An i.S. r PhD. intbe ove d is dsirabl Specific nilies willinckude (i) dsn of a research and d pro-

removtoe nut ts foim agi-) rensearchi)on nutrient ,mpacts,

on caiti and mana t tcu frfirshwe weta (iii) ad tn of research con-tt. Strting salary $27,352 to mioint $34,860commemurate with qualificatos. icaons may beobained ifm The eonn Ol, Soth FlodWaterManme Dis , P.O. Box 24680, WestPalm Bea , 33416-4680 or call: 407-686-800,n 726. The deadline for is 5:00

p.m. on 14 November 1988. Equd Employr.

SCIENCE., VOL. 242332

GRADUATE PROGRAMCELLAND MOLECULAR BIOLOGY

(MULTI-DEPARTMENTAL)

* GENE REGULATION* MOLECULAR GENETICS* DEVELOPMENTAL BIOLOGY* ONCOGENES AND GROWTH FACTORS* SRUCTURAL BIOLOGY* NEUROBIOLOGY* MOLECULAR VIROLOGY AND IMMUNOLOGY

The Graduate School at BAYLOR COLLEGE OFMEDICINE has recendy created a graduate program inCEL-L AND MOLECULAR BIOLOGY stressing basicresearch in the above areas. Students accepted forstudies leading to the Ph.D. degree will receive financialsupport. For further information contact:

Dr. Savio Woo, DirectorGraduate Program in Cell and Molecular BiologyBaylor College of Medicine, Room 185AOne Baylor PlazaHouston, Texas 77030Phone: (713) 799-6557

Staf ScientistThe Health Effects Institute (HEI) is an independentnonprofit organization that sponsors and evaluatesresearch on the health effects of automotive emis-sions. It is jointly funded by the United States En-vironmental Protection Agency and the domesticand foreign automotive industry. HEI is seeking astaff scientist to work with the Institute's HealthResearch Committee and other staff scientists todevelop and oversee its research program.

Applicants should have the following qualifications:Ph.D., M.D., or equivalent degree; relevant scientificexperence; an interest in science management andenvironmental problems; and good communicationskills. Research experience in the following areas isparticularly desirable: exposure monitoring,epidemiology, or lung physiolgy and pathology. In-dividuals with other backgrounds will also be con-sidered. Salary commensurate with experience.

Send curriculum vitae and the names and ad-dresses of three references to: Dr. Jane Warren,Hlth Eflets InstItute, 215 First Stree, Cam-brIdge - A02142, by November 14, 1968 An Af-firmative ActkmlEqual Opportunity Employer.

The Health Effects Institute

NATIONAL SCIENCE FOUNDATION (NSF)NSPs Division of Asronomical Sciences is seeking quali-fied applicants to fill the position of Program Manager,Astronomy Centers Section. The position will be filled on apermanent basis; or rotator/tmporary basis for one-twoyears, and is excepted from the ctive civl senrice.Th salary range is $46,679 to 72 per annum.The Section is responsible for the funding and oversight ofthree National Astronomy Centers. The ProgramM gerhas the Founton's lead responsibility for und ingthe scientific and technical content of Center programs. Theincuet will serve as the principal point of contact in theNSF for m s conceming the a ned Center; monitorscientific and technical work r an isting award;coordinate rmews d prov sis of prposed newor upgraded facilities; de p and lng r eplnning information to suppor Administration reque tothe Congress; accomplish a variy of administrative tasksconneced with finding acions for the Centers programs.Aplicants should have a Ph.D. in a or astrophys-ics or equivalent experence. In addition, 4 or more years ofsuccul indepent scentific research experience andsome pr n e t expence togeh r with knowl-edgeoftechn gyatechecniques likei to be pplied int programs in the Center are required.For tchnical information concerning the position contactDr. Kurt Riegel, Head, Astronomy Centers Section,202) 357-9450.Applicants should send resume or SF-i 71, Application forFedradl Employment to: National Science Foundation, Divi-sion of Personnel and Management, 1800 G. St., NW.,Washinon, DC 20550. Attn: Catherine Handle. For furtherinfomation call 202/357-7840. Hearing impaired individ-uals should call TDD 202/37-7492. NSF is an EqualOppotunity Employer.

I I

i

r

0

POSIIONS OPEN

RESEARCHtiASSOUTE posion miavadable fir a Ph.D. with sonepl

t conduct indepent research on thelfof diet on mary ca in vitro and in vivo.

Salary $24,000 to $30,000 phus benefits. Send auricu-h,m vire, iFMonnbMeSolf lhcatmnnfaor fereest: MtHar, Eml , 262 8vsi-sunlAwonuIling Unwrsy o WesfternOter-, Lnn, On i,C n6A 5. in aeniac

wit Canaa Itibn hisds 'oim is&Cadato Canadian dize andpmmennIanreidIsts ofCan6.An Equal Opportasity FEnpioyer.

lousiana Stat Univ (ISU) Eye Cnter is look-ing fix a SENIOR. PHAAMCOLAITshould be interestd ingddivay t

odter areas ofreserh wig be a

I;W J&dalpnam aCg:amlE

K _isan D. ISBU Eb Cenft 2020Gvi _Sfw&itBs Narw OdeLA 7011 SUMC is w E9wd

fnloyn Oppasmaity/Afoaive Action Emplyfr.

S OR SCrouP DE Opporunty idescentfic dirtion in an intedisc-

pliaryreearh rogamin Grand Ca"nyt. Tfhis 2-yeareension o yar Gen CayonStudies wil fiam ons-tm sies on t ofdam reles on dfishes, ubeachst,and resourc s, wd s devdo of ala*g-tnm resarch pi. Apascant dege of rcearchenc,iwh ex e ise us U-incecologyIor rdated b orrdkand prvd leadalup _critiaL Send iRt: TOmBurea, of R11a-adn, Uppu dP.O. BaK 11568, Sak a i UT 84147An Fual Oppomauy/Afsave Aco Employer.

SPACE LIFE SCENCESPROCr AND

CURRICULUM ASSIsWfNSIhe NASA Space Life Sdcn Taining Prm at

the Kcnnedy Ceter is acpg a n hrt and o

Aulifesinelbrtr pqects to be inldd in anie _I pm X~~w e lansineniv um eduaioa program foxudrgau

atem. Thes stff podtons offer on th job exposre toNAs le scn opei and warch er de

ogy (vesiua, cdovcuar,ormucsd),platphysio-

at 407-567-252L. Aplcns should sed a letrofinterest, curriuhni and thred let ofrfe

by1Decmberw198to: , i umnp

John L Puilor2kinCdes R 1ant

ennedySpae C_O, FL 32899An Equa oat lyer

DEPARTMENT OF BIOCHEMISTRYTENURE-TRACK POSITIONS are availble frIcmn, 1989in ere of p l b y

lsivstohnf thireo of amea t ofene ntribus todsese pre-tie. Prreewilb cnappin at teleo

massitn profesrbetcandidTes atm seiornk

a UR-oAC POSON ar mblbl fhiw.d

research ba d amd itess, ad r l ofrennndto to: Faut Serc Connts, Dc-

00armofdwtofL smofUtaSdaon,

of8edlk,Sat lAeCu1, UT 84132. Dedln fxappls.icatis is 1 December ap;p cainat may

becosidetredifmopeingcniaresstill wmrak

LI= 4 od~Awand'Bqa an dceyFeF o

334

POSITIONS OPEN

STAFF PHYSICIAN with the Adm -tion Medical Centr and asisan prfso of medicine(infectiousdisea), UnvyofalOfaMxiaSan Diew.Applicant shouldb apbeo etblishing an independent resach progrm rad to HW tio andwill be exetdt atcpt ndinical and tahn

activities.We se an EqualOo y Eoye. Pleasesnd curuhm v ad names of frnces : Dr.Jol_a Fir (llPO, VA Medial Center 33 IAJlla Viag, Dri, Sen Diegp, CA 92161.

umicalgaQstpn

c iencs and stat i esential as are

24nElalO mc A ophy 3

to mnenO QA p U.S.shiptovsat ens of e :o io ,679to

thseifcann o ree rctoompe ntitesso

S40,683. CAmm M& Pat_AsiC"l pa-

exitn faulY. Ph.D. in toxiolog orar UaeT

expectedt developan extenally ded res80141er-21p togram into7:00amn6 5:r30p.mt maDT,finAn edOnpat themS. AfvcniWubm.

vitae,aOLOGiST.Tof ecnurs-eaor-t

stateicug interts,nD.i d or aled fidd;p_I_L % c~~~q_bc wig bc

9 in~edein=thc S.Im s b

soem reeac F- c1 ad mc-daton by21 November, 1988 to: Dr.D

Wayn, IN 4606m- Aqon

VETEIR ,PATHOLOGI. Ie Yrkes Pd-

ingfxraetrnrptloit

Anusofreearduthilsotndss~o

anddi diehnr0to fi.

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_s, Gary Strul ainah Taei , l latler,Kbsdum , udRebut m¶nyAcas fr de

MD., Ph.D, or D.VJL dep-, ind be U.S.

iizorhave pr enc st. Send cauc-uha ck, a .-tdc di axd

Bd 722 Wet 166 Stree New

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© 1988 The Hewlett-Packard CompanyAG04804

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