iis f 2019 kolkata young s cientists’ confer ence abstr ... · the independence polynomials are...

Ministry of Science & TechnologyMinistry of Earth SciencesMinistry of Health Family WelfareGovernment of INDIA

ORGANISERS

Young Scientists’ ConferenceIISF 2019 Kolkata

Abstract Book

IISF KOLKATA, 2019

Preface

The Young Scientists Conference (YSC) of the India International Science festival (IISF-2019) was held in

the Biswa Bangla Convention Center (BBCC) in Kolkata during November 5-7, 2019. The grand event was

inaugurated in the august presence of Prof. Ashutosh Sharma, Secretary, DST, Dr. Sekhar C. Mande,

Director General, CSIR, Prof. Vijay Bhatkar, Chancellor, Nalanda University and President, VIBHA and

Shri. U. Rajababu, Project Director, Mission Shakti, DRDO at the Main Hall of Biswa Bangla Convention

Centre.

The conference brought near about 1500 researchers including experts from different subjects.

Around 1400 young scientists/researchers/PhD scholars/post-doctoral fellows/entrepreneurs from various

universities, post graduate colleges, engineering colleges, R&D organizations, national laboratories, IITs,

NITs, IISERs, Industries and NGOs under the age of 45 participated YSC to discuss their research findings

and exchange innovative ideas on the identified research themes such as - Make in India, Bio Diversity,

Frontier Areas of Sciences, Swachh Bharat, Swasth Bharat, Digital India, Water Crisis and

Conservation.

The conference activities were spread over three days with plenary, oral and poster sessions. There

were interactive panel discussions on entrepreneurship, various aspects related to career progression,

overseas education and opportunities for the young scientists. The dignitary representatives of embassies

highlighted various educational programs of various countries. Near about 1000 delegates presented their

scientific research through poster presentations.

This book of abstracts showcases the research findings of the brilliant minds of the country. Even a cursory

look at the themes of the book of abstracts tells the huge potential and progress being made by our

researchers in India.

YSC organizing committee thanks all the participants for making this event a grand success.

"Do not be led by others, awaken your own mind, amass your own experience, and decide for yourself your own path." ~ Atharva Veda

Coordinators, YSC Jajati K. Nayak Ayan Datta

Ms Gargee ChakrabortyImage Delegate ID Theme Details

YSC 10066Frontier areas of

Research

Category : MathematicsOrganisation : Amity

University KolkataDesignation : Mathematics

PH.D Research Scholarr

Title: Cosmological Consequences of a Dark Energy Model in the Framework of Bulk Viscosity Authors: Gargee Chakraborty* and Surajit Chattopadhyay *Communicating author email: [email protected] Affiliation: Dept of Mathematics, Amity University, Kolkata, Major Arterial Road, Action Area II, New Town, Kolkata 700135

Abstract: Late time acceleration of the universe is well documented through observational studies [ 1,2]. The present study reports an investigation of a candidate of dark energy , characterised by higher derivatives of Hubble parameter , in presence of bulk viscosity. The bulk viscous pressure has been considered to be a function of Hubble parameter. Modified field equations have been considered in presence of bulk viscous pressure . Cases of interacting as well as non interacting scenarios have been taken into account for the dark energy model , which is actually a special type of holographic dark energy [2]. It has been investigated how the influence of bulk viscosity is evolving in the different cases undertaken . The equation of state parameters have been reconstructed for various cases and the conditions for quintessence or phantom behaviour have also been demonstrated for the various cases. Alongside solving Hubble parameter from Friedmann equations , the cases for power -law choice of scale factor have also been studied. It has been observed that it is possible to cross phantom boundary in presence of bulk - viscosity for the dark energy candidate under consideration. Attainment of LCDM phase has also been investigated for various cases.

References: [1] E. J. Copeland, M. Sami, S. Tsujikawa, Dynamics of Dark Energy, Int. J. Mod. Phys. D, 15, pp 1753-1935 (2006). [2] K. Bamba, S. Capoziello, S. Nojiri, S. D. Odintsov, Dark energy cosmology: the equivalent description via different theoretical models and cosmography tests, Astrophys. Space Sci., 342, pp155-228 (2012).

Dr Sabyasachi MondalImage Delegate ID Theme Details


Research


University KolkataDesignation : Assistant

Professor

A theoretical analysis on hydromagnetics nanofluid employing CVFEM

Sabyasachi Mondal*, Sharadia Dey

* Department of Mathematics, Amity University, Kolkata, Newtown-700135, West Bengal, India Department of Enviromental Studies, St. Xavier’s College (Autonomous), Kolkata, West Bengal, India

Contact Author’s e-mail address: [email protected]

Abstract: The heat transportation features of current liquids are improved exceptionally via suspension of nano-sized solid elements having diameter ( Keywords: Nanofluid; Natural convection; Magnetic field; CVFEM; KKL method.

Ms RIYA GHOSHImage Delegate ID Theme Details


Research


university kolkataDesignation : student

Study on Casson nanofluid flow through an electromagnetic stretching Riga plate using Spectral local linearization

Riya Ghosh*, S. Mondal

Department of Mathematics, Amity University, Kolkata, Newtown- 700135, West Bengal, India Contact Author’s e-mail address:[email protected]

Abstract: In this paper we investigate entropy generation in a Casson nanofluid flow past an electromagnetic stretching Riga plate. The study includes the effect of viscous dissipation. We solve the model equations using spectral local linearization method. The study considers the effects some other physical parameters like the Casson, velocity ratio and electromagnetic parameters. A good correlation is achieved when the present results are compared with published literature. The results indicate that the fluid flow, temperature and concentration profiles are significantly influenced by the parameters considered.

Keywords: Entropy generation, Riga plate, Casson nanofluid, spectral local linearization method.

Ms MEGHA P MImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : KKTM

GOVERNMENT COLLEGE PULLUT,KODUNGALLUR

Designation : ASSISTANT PROFESSOR

Many large graphs can be obtained from existing smaller graphs by using graph operations such asthe graph products. Let G be a finite group and S be an inverse closed subset of G which does notcontain the identity element of the group G,i.e.S=S^(-1),such that 1?S. The Cayley graph ?=Cay(G,S)on G with respect to S is a graph with vertex set G and edge set {{g,sg }|g?G,s?S}. ? is connectedif and only if G=. The four kinds of graph products such as Cartesian product, Tensor product,Strong product and Lexicographic product of two Cayley graphs are also a Cayley graph [2]. But onlyTensor product of two Cayley graphs such as ?_1=Cay(G,S) and ?_2=Cay(H,T) is also a Cayley graph ?=Cay(G×H,S×T)of group G×H with relative to subset S×T of that. In this paper, we study theTensor product of Cayley Graphs of finite abelian groups and its properties. Let R be a finitecommutative ring ,Z(R) be the set of all zero divisor elements. The Zero- divisor Cayley graph of Rdenoted by ZCAY(R)is the graph obtained by setting all elements of Z(R) to be vertices definingdistinct vertices x and y to be adjacent if and only if x-y ?Z(R) .We also offer some results ofTensor product of two Zero-divisor Cayley graphs of ring R

Ms SREEJA K UImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : KKTM

GOVERNMENT COLLEGE, PULLUT, THRISSUR


Graph polynomial is a graph invariant whose values are polynomials and found many applications in different fields of science. Important graph polynomials include characteristic polynomial, the matching polynomial, the chromatic polynomial, Tutte polynomial and the independence polynomial. The independence polynomial has a long history dating back to a paper by Harary and Gutman in 1983. The independence polynomials are almost everywhere, but it is an NP complete problem to determine the independence polynomial of a graph.The goal of this paper is to connect the theory of fractal geometry to the theory of the much broader class graph theory using independence polynomial as basis of our fractals. The relationship between a graph and its independence fractal still a question. We are particularly interested in Julia sets and Mandelbrot sets.The roots of the independence polynomials of a graph converge to the Julia set, thereby associating graph with a fractal. Mandelbrot graph is useful for the connectivity of a Julia set of independence polynomial. Using Mandelbrot graph we established what the structure of the fractal says about the graph. The energy of a graph is one of the emerging concept within graph theory. This concept serves as a frontier between Chemistry and Mathematics. A natural question arises is how the energy of a given graph can be related the Hausdorff dimension of the fractal obtained from the graph. Independence polynomial of second degree of different types of graphs are examined and their possible connection between energy and Hausdorff dimension studied. The various relations between independence polynomial, energy, Julia set and Hausdorff dimension of different classes of graphs are closely examined. This paper concludes with a discussion of connectivity of Petersen graph, a small graph that serves as a useful example and counter example for many problems in graph theory.

Ms SANGHATI SAHAImage Delegate ID Theme Details


Research


University KolkataDesignation : MSC Applied

Mathematics (final Year)

Sanghati Saha* and Surajit Chattopadhyay *Communicating author email: [email protected]

ABSTRACT Observational studies through distant Supernova Ia analysis revealed that the current universe is passing through a phase of accelerated expansion and exotic matter characterised by negative pressure, and negative equation of state parameter (EoS) w, is considered to be driving force behind this late time acceleration of the universe [1]. This is dubbed “Dark Energy (DE)”. Although the exact nature of DE is yet to be known, different candidates have been proposed till date in the literature [2]. The various model can be broadly differentiated into four types; Cosmological constants, Scalar field models, Holographic dark energy and Chaplygin gas models. The focus of the present work is to consider the fourth variant in one of its modified forms. Instead of considering the universe to be non-viscous, we have considered a form of Chaplygin Gas [2] in presence of bulk viscosity where the bulk viscous pressure is a function of Hubble parameter. The present work demonstrates DE in the form of Standard Chaplygin Gas (SCG). Considering the universe filled with SCG and pressure-less dark matter (DM) the various statistical parameters have been reconstructed for a power-law form of scale factor. The behaviour of EoS parameter has been investigated and the state finder trajectories have been reconstructed. The stability of the model has been checked through squared speed of sound and the slow-role parameters have been derived to have some insight into the behaviour of the model against gravitational perturbations.The influence of bulk viscosity has been thoroughly demonstrated. Also it has been checked for its consistency with cosmic microwave background (CMB).

References [1] A. G. Riess et al. Astron. J. 116 (1998) 1009. [2] E. J. Copeland, M. Sami and S. Tsujikawa, Int. J. Mod. Phys. D 15 (2006) 1753.

Dr Sabna K.SImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation :

K.K.T.M.Government CollegeDesignation : Assistant Professor

THE CONCEPT OF L-SLICE OF A LOCALE L AND ITS APPLICATION TO CRYPTOGRAPHY Sabna K.S*, Mangalambal N.R Department of Mathematics, K.K.T.M Government College, Pullut,Thrissur, Kerala,India , Pin-680663 Department of Mathematics, St.Joseph’s College Irinjalakuda, Thrissur, Kerala,India Pin-680121 Email: [email protected] In the background of pointfree topology, given a locale L and a join semilattice J with bottom element 0J, a new concept called L-slice, denoted by (?,J), is defined, where ? is an action of the locale L on the join semilattice J , together with a set of conditions. The L-slice, though algebraic in nature adopts topological properties such as compactness through the action ?. Several di?erent aspects of L-slice for a locale L have been obtained. Using the algebraic properties of the L-slice (?,J),a congruence R on the L-slice (?,J) is obtained. We have proved that the pair (?,J/R), of all equivalence classes with respect to the congruence R on the L-slice (?,J), is an L-slice, where the action ? is de?ned in terms of ?. The L-slice and its properties are utilized to extend the existing Di?e-Hellman key exchange protocol to the background of L-slices of a locale L. To ensure optimum security in the system, a modi?cation in the extended Di?e-Hellman key exchange protocol is developed. This modi?cation assures optimum security of the system since the function ?:L×J?J is not invertible. References: 1. W Di?e, M.E Hellman (1976), New directions in cryptography, Information Theory, IEEE Transaction, 22, 644-654. 2. P.T.Johnstone,The point of pointless topology, Bulletin of American Mathematical society,1983. 3. P.T.Johnstone, StoneSpaces, CambridgeUniversityPress,1982. 4. J.Picado,Pultr, Frames and locales:Topology without points, Front.Math.,Springer,Basel,2012

Mr ANKUSH CHANDAImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : NIT

DURGAPURDesignation : RESEARCH

FELLOW

The objective of this manuscript is to enquire for the solvability of a specific type of non-linear quadratic integral equations via the interesting notion of measure of non-compactness. Firstly, we inquire into a couple of exciting fixed point theorems involving a measure of non-compactness in the setting of a Banach space. Subsequently, bringing into play a suitable measure of non-compactness and the acquired results, we discuss the existence of the solution to the aforementioned kind of non-linear quadratic integral equations.

Ms Mary Elizabeth AntonyImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Mar Athanasius college

Designation : Assistant professor

GRAPHS ASSOCIATED WITH L-SLICES Mary Elizabeth Antony*, Mangalambal N.R

*Department of Mathematics, Mar Athanasius College, Kothamangalam, Kerala – 68666. Research Supervisor, Centre for Research in Mathematical Sciences,St.Joseph’s College Irinjalakuda, Kerala-680121. * Email : [email protected] Abstract: For a locale L and a join semilattice J an action ?:L×J?J yields the structure (?,J), called L-slices. L-slices are the localic counter-part of the algebraic concept of modules. The concept of L-slices incorporates the theories from both the algebraic and localic backgrounds. The graph theoretic concepts are already introduced and studied in the background of modules. The presentation investigates the possibility of introducing graph theory in the realm of L-slices. We have come across three different types of graphs that can be associated with L-slices, namely, the graph related with the knot points of a filter F of the locale L denoted Knot F , total graph and the weak Zariski topology graph G_T (?^*). We have derived a characterization for the total graphs and G_T (?^*) to be non empty.The structural properties like radius, diameter, girth, clique number, chromatic number of the graphs are investigated and some important results are obtained.

References: 1.A.Abbasi,H.Roshan Shekalgourabi,D.Hassanzadeh-Leklekaami ,Associ- ated graphs of Modules over a commutative rings, Iranian Journal of Mathematical Sciences and Informatics 2015, 10, 45-58. 2.H.Ansari Toroghy, SH.Habibi , On the graph of modules over commutative rings, Rocky Mountain Journal of Mathematics 2016, 46, 729-747. 3.R.Balakrishnan, K.Ranganathan ,A Text Book of Graph Theory, Springer 1991. 4.Frank Harary ,Graph Theory, Narosa Publishing House 1988. 5.Sabna K.S, Mangalambal N.R ,Fixed points with respect to the L-slice homomorphism? ??_?, Archivum Mathematicum 2019, 55, 43-53. 6.Sabna K.S, A Study on Properties of Locales, Action of Locales and their Applications, Ph.D thesis, University of Calicut, 2018. 7.Zoran Pucanovic ,The Total graph of a module, Matematicki vesNik 2011, 63(4),305-312.

Ms Srishti PalImage Delegate ID Theme Details


Research


University, KolkataDesignation : M.sc. (Appl.

Math.) Final Year

Rescaled range analysis based Hurst Exponent approach to the summer monsoon rainfall over northeast India Srishti Pal*, ShrutinilDutta, TamannaNasrin&SurajitChattopadhyay Dept of Mathematics, Amity University, Kolkata 700135 *Contact author’s e-mail address: [email protected]

Abstract: The work reported here deals with the summer monsoon rainfall (SMR) over northeast India. It has been observed that although a Normal distribution fits the time series, no persistence forecast is possible as indicated by the low value of the Lag-1 autocorrelation coefficient. A linear regression over time has also been found to fail. Considering these, it has been decided to test the long-term behavior of the time series through a deeper insight in terms of Hurst exponent through rescaled range analysis. It has been found that the Hurst exponent [1] is far below 0.5 and thus it has been interpreted that there exists a long-term switching between high and low amounts of SMR over northeast India. However, the Hurst exponent value is low, it has been inferred that the SMR time series over northeast India is volatile and rough. In this context lest us mention that the coupling of the El Niño–Southern Oscillation (ENSO) with the ISMR is well documented in the literature. Years of drought in India are usually allied with warm ENSO or El Niño years while the years of surplus rainfall go with La Niña. Although based on this study it is not possible to have a strong connection between the behavior of the time series of the SMR and ENSO, it may be loosely stated that the switching between high and low amounts of SMR over northeast India reflected in the Hurst exponent value is to some extent associated with the deficit rainfall in El Niño. References: 1.Karmakar, S.; Goswami, S.; Chattopadhyay, S. Atmosphieric. Research.2019, 217, 57-62.

Mr Trupil LimbasiyaImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : BITS Pilani -

K K Birla Goa CampusDesignation : Full Time PhD

Student

Generally, vehicles are mostly used as moving devices, and most people use different transport facilities such as private and public. However, the rapid development of our economy and society has made it essential that pivotal emphasis should be given to vehicular communication research for smart cities and villages. Today, the focus is shifting from the inside parts to the ecosystem around it, and it enables us to create new experiences throughout the lifecycle of our vehicles. Thus, an innovative idea of autonomous vehicles has transformed the way of thinking of researchers, and hence, more focus has been given on this emerging area. Consequentially, the Internet of Vehicles (IoV) concept came into the picture by connecting Internet of things (IoT) and vehicular ad-hoc network (VANET) to exchange meaningful data (e.g., real-time traffic, vehicle service and update, driving behaviour, advertisement, toll payment credentials, usage-based insurance, and so on) on the fly. Therefore, we will have new smart city applications and cutting-edge business opportunities.

However, there are diverse challenges in the IoV framework due to on-fly computation and insecure channel data transmission. Further, on-device performance is critical, but data damages and secure on-time connectivity are also significant challenges in public environments because unauthorized access or bogus data dissemination creates disasters on the road, and it makes a massive loss to surrounding people. Besides, the IoV structure is a vital part of a knowledge city and is a unified network system to connect vehicle applicants, automotive, and ubiquitous technological systems concurrently. From this impression, it is essential to design and develop secure and energy-efficient data transmission protocols using cost-effective cryptographic primitives. Moreover, the presenter will discuss the importance of smart city applications, business opportunities, security requirements, and the significance of low-cost computational resources for different performance measures.

Ms Samayita Nag RayImage Delegate ID Theme Details


Research


University, KolkataDesignation : M.sc. (Appl.

Math.) Final Year

Authors: Samayita Nag Ray*, Sanghita Bose, Surajit Chattopadhyay *Communicating Author: [email protected] Abstract The present work demonstrates a Markovian approach to probe into the behavior of the surface temperature time series over North-East India. The study period is chosen as 1999-2007. Monthly data corresponding to the random variable of surface temperature is a continuous random variable. As we have considered two-state Markov Chain [1] model, the data have been discretized to a binary time series consisting of 0 and 1. The transition counts and probabilities have been computed and presented in a transition diagram. Different orders of Markov Chain have been tested and the appropriate order has been tried to be identified through Bayesian Information Criteria(BIC). It has been revealed through this approach that first-order two-state(FOTS) Markov Chain describes the time series and it has further been supported by chi-square test. Finally, it has been concluded that the surface temperature time series over North-East India has the behavior that the current state depends only upon the immediately previous state and not upon the long way through which the system has reached up to that state. This indicates and intrinsic randomness within the time series. Also, this observation is physically consistent with the occurrence of severe weather phenomenon [2] during pre-monsoon season over this region, for which surface temperature has a very significant role to play. As a future study, a similar analysis in seasonal scale is proposed. References: [1] D. S. Wilks, Statistical Methods in Atmospheric Sciences, Academic Press, 2011 [2] S.Karmakar,S.Goswami,S.Chattopadhyay, Atmospheric Research 217,57-62(2019), Exploring the pre and summer monsoon surface air temperature over Eastern India using shannon entropy and temperal hurst exponents through rescaled scale analysis

Mr Debjyoti ChatterjeeImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Jalpaiguri

Government College, Jalpaiguri

Designation : Assistant Professor in Mathematics

(WBES)

Abstract: The word ‘multiset’ (mset, for short) which abbreviates the term ‘multiple-membership set’, is now the commonly accepted name for this concept, replacing ‘bag’, ‘bunch’, ‘weighted set’, ‘occurrence set’, ‘heap’, ‘sample’, and ‘fireset’ – finitely repeated element set. D. Blizard first studied multiset in 1989; he made a thorough study of multiset theory, real valued multisets and negative membership of the elements of multiset. In this paper, I have redefined some of the concepts related to multiset theory and have studied some of their properties. In addition to it I have developed a ‘multi-real number system’ and have studied the algebraic operations and order relations defined on it. I also have defined multi-metric space in multiset settings using multi-real number system. Multi-open sets, multi-closed sets are defined as well as completeness of multi-metric spaces is also studied. Cantor’s Intersection theorem is also proved in multi-metric space settings.

References: 1. Wayne D. Blizard, Fuzzy Sets and Systems, 1989, 33(1), 77 – 97. 2. K. P. Girish; S. J. John, Inf. Sci., 2009, 179(6), 758 – 768. 3. Debjyoti Chatterjee; S. K. Samanta, International Journal of Mathematics Trends and Technology (IJMTT), 2017, 48 (2), 136-146. 4. Debjyoti Chatterjee and S. K. Samanta, Annals of Fuzzy Mathematics and Informatics, April 2018, 15(2), 149-167.

Ms ALIFIYA SAIFEEImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : SARDAR

VALLABHBHAI NATIONAL INSTITUTE OF TECHNOLOGY

Designation : STUDENT

The proposed research work is entitled ”The study on Diabetes by Mathematical Modelling” . Firstly it gives basic introduction to Mathematical Modelling, describing its characteristics and also mentioning its few applications. Then we move forward with a basic Note of Diabetes, Explaining about different types of diabetes its symptoms, treatment and prevention. Moving towards the core part, it displays a numerical model of glucose metabolism including the digestion of carbohydrate as a factor affecting blood glucose concentration for type 1 diabetic patient. It includes a comparative study of glucose metabolism for different types of food. The model involves the differential equations for change in concentration of glucose, insulin and epinephrine in which factors for physical activities and carbohydrate affecting glucose concentration are also included.This work represents glucose level picked up by various food items for both exercising and non-exercising person. Last part presents a new mathematical model for Blood Glucose Regulatory System(BGRS) which includes epinephrine as a third variable; and whose solution has been analyzed for equilibrium and stability to provide the blood glucose concentrations for diabetics and non-diabetics

Mr RAJNISH KUMAR DUBEYImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : CSIR-Central

Institute of Mining & Fuel Research

Designation : Project Assistant (CSIR-CIMFR)&

Research Scholar (IIT-ISM),

The moment we hear a word ‘mining’, immediately a thing that comes to our mind is‘dirtiness’. Of course, it is a dirty business. However, India depends upon coal miningindustries for 72% of its energy-need1. The emission of aerodynamic particulate matters2 due tofrequent movement of heavy vehicles during various mining operations and the toxic gaseouspollutants such as SO2, NOx, CO2 and CO due to frequent burning of diesel in heavy vehicles and minemachineries involved coal mining operation are the major source of gaseous pollutants in coal miningindustries3,4 are the major pollutants in the mining areas. Kankanee Colliery is one of thesubsidieries in Sijua area of Bharat Coking Coal Limited with a normative production capacity of0.48 million tonnes per year and a peak production capacity of 0.624 million tonnes per year5.Various sources of fugitive dust emission were identified and emission rates of suspendedparticulate matters were studied and compared. It was observed from the study that the haul roadcontributes maximum particulate matters in the atmosphere. Further, a study on concentrations ofPM10, PM2.5 and PM1.0 during winter and summer seasons from November 2016 to June 2019 were carriedout at 21 locations covering industrial areas as well as residential colonies in and around the mineusing HCT’s Model PM-101P Particulate Matter’s Monitor, ver. 1.0.. Site specific mathematicalrelationships between the concentrations of PM2.5 and PM1.0 with PM10 have been established usingstatistical analysis of the air quality data for the study area. The pollution scenarios ofparticulate matters at different seasons in and around the mining industry have been visualizedcategorizing into different classification of pollution level using appropriate presentation toolsand also suitable air pollution control measures have been devised.

Ms SANGHITA BOSEImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : AMITY UNIVERSITY KOLKATADesignation : STUDENT

Authors : Sanghita Bose*, Anindita Bhattacharyya, Amit Pal. *Communicating author email: [email protected] The dynamic relationship between predators and their prey has long been and will be one the dominant themes in both ecology and mathematical ecology due to its universal existence and importance.Differential equation models for interaction between species are one of the classical applications of mathematics to biology.A biological realization of this study is the herds of two preys,buffalos and gazelles living side by side and attacked by one type of predator lions.Current work presents the deterministic analysis of a two prey one predator system with realistic predator-dependent Beddington-DeAngelis functional response which is similar to the Holling type II functional response except for the fact that it contains an extra term describing mutual interference by predators.This theoretical study of dynamical behaviours of the system is started by showing the uniform boundedness of the system which in turn,implies that the system is biologically well behaved.Also boundedness of a system together with the stability analysis of the boundary equilibrium provide all the necessary information to establish persistence of the system.It is observed that the necessary and sufficient condition for the local asymptotic stability of the interior equilibrium point is satisfied which implies that the co-existence equilibrium points were stable equilibrium points under some conditions.The work presents the stability and bifurcation of the most important interior equilibrium point.It is observed that this point is locally asymptotically stable in absence of delay and there exists a critical value of carrying capacity of a prey such that the interior equilibrium point loses its stability as carrying capacity crosses the critical value. References : 1. Beddington JR(1975) Mutual interference between parasites or predators and its effect on searching efficiency, J.Animal Ecol., 44, 331340.

Mr RAJNISH KUMAR DUBEYImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : CSIR

CENTRAL INSTITUTE OF MINING AND FUEL

RESEARCHDesignation : PROJECT

ASSISTANT AND RESEARCH SCHOLAR

Development of Empirical Models to Estimate Emission Rates of Fugitive Dust and Statistical Analysis of PM10, PM2.5 and PM1.0 in and around a Surface Coal Mine with Appropriate Control Remedies

R.K. Dubey1*, M. Sundararajan2, J.K. Pandey3 and M.K. Jain4 1-3CSIR-Central Institute of Mining and Fuel Research, Dhanbad – 826 015, India 4IIT-ISM, Dhanbad – 826 004, Jharkhand, India *Corresponding Author: [email protected]

Abstract The moment we hear a word ‘mining’, immediately a thing that comes to our mind is ‘dirtiness’. Of course, it is a dirty business. However, India depends upon coal mining industries for 72% of its energy-need. Kankanee Colliery is one of the subsidieries in Sijua area of Bharat Coking Coal Limited with a normative production capacity of 0.48 million tonnes per year and a peak production capacity of 0.624 million tonnes per year. Various sources of fugitive dust emission were identified and emission rates of suspended particulate matters were studied and compared. It was observed from the study that the haul road contributes maximum particulate matters in the atmosphere. Further, a study on concentrations of PM10, PM2.5 and PM1.0 during winter and summer seasons from November 2016 to June 2019 were carried out at 21 locations covering industrial areas as well as residential colonies in and around the mine using HCT’s Model PM-101P Particulate Matter’s Monitor, ver. 1.0.. Site specific mathematical relationships between the concentrations of PM2.5 and PM1.0 with PM10 have been established using statistical analysis of the air quality data for the study area. The pollution scenarios of particulate matters at different seasons in and around the mining industry have been visualized categorizing into different classification of pollution level using appropriate presentation tools and also suitable air pollution control measures have been devised.

Dr Papiya DebnathImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Techno International New TownDesignation : Assistant

Professor

Abstract: The lithosphere-asthenosphere system has been represented by layered viscoelastic media consisting of a viscoelastic layer of Maxwell type overlying a viscoelastic half space of liner viscoelastic solid. A long inclined surface breaking strike-slip fault is taken to be situated in the first layer. The medium is taken to be under the action of a tectonic forces arising due to different tectonic phenomena such as mantle convection etc. Expressions for displacement, stresses and strain are obtained during the aseismic period in between two major seismic events. Stresses are found to accumulate near the fault leading to a sudden movement across it resulting in an earthquake. The movement across the fault effect the nature of stress accumulation in the region. In this paper an attempt has been made to obtain an estimate of time to the next major event. Such studies are directly associated with the prediction of an impending earthquake in a medium which has non-homogeneous character.

Keywords: Strike slip fault; Viscoelastic material; Aseismic state; Earthquake prediction; Mantle convection

Dr Ved Prakash BHARDWAJImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Govt. Arts, Commerce and Science

College Sukhtawa Hoshangabad MP

Designation : Faculty, Department of Mathematics

The purpose of this paper is to prove a fixed point theorem for contractive type condition in fuzzymetric space using new type of common limit in the range property. Our result generalizes, extendand enrich several classical and very recent related results in literature of fixed point theory.

Dr BIKASH CHAKRABORTYImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Ramakrishna

Mission Vivekananda Centenary College

Designation : Assistant Professor

Two meromorphic functions are said to share a set S in ignoring multiplicities (IM) if S has the same pre-images under both functions. If any two nonconstant meromorphic functions, sharing a set IM, must be identical, then the set is called a reduced unique range set for meromorphic functions" (in short, RURSM, or, URSM-IM). From the existing literature, it is known that there exists a RURSM with seventeen elements. In this article, we reduced the cardinality of an existing RURSM and established that there exists a RURSM with fifteen elements. Our result gave an affirmative answer to the question of L. Z. Yang.

Ms MITAL MISTRYImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : THE

MAHARAJA SAYAJIRAO UNIVERSITY OF BARODA,

VADODARADesignation : RESEARCH

SCHOLAR

Present investigation explores effects of radiation and variable viscosity on electricallyconducting Williamson fluid over a non-linear stretching sheet. Viscosity of the fluid is dependenton temperature and thermal diffusion. Mathematical modelling of the problem results in system ofPDEs, converted into non-linear ODEs using transformations. Solutions of the problem is achieved byapplying Homotopy Analysis Method. Effects of pertinent parameters on concentration, velocity andtemperature gradients are discussed through graphs. It is observed that magnetic parameter decreasesthe velocity profile. For large values of Weissenberg number, Brownian moment parameter, magneticparameter, variable viscosity parameter and thermal stratification parameter the velocity profiledecreases. Temperature reduces throughout the boundary layer region for large values of Prandtlnumber and temperature raising for large values of thermophoresis parameter and thermalstratification parameter. For large value of Lewis parameter concentration decreases and thestretching index increases. Skin friction coefficient improves for changing the values of magneticparameter. Heat diffusion rate decays for increasing values of Prandtl number.

Ms JAYA LAKSHMIImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Sri GVG Visalakshi College For Women(Autonomous)Designation : Assistant Professor

Several problems in fuzzy graph theory concern manners in which one can move about in fuzzygraph.For the purpose of studying questions such as these it is useful to introduce some newconcepts like fuzzy walk, fuzzy path and fuzzy trails. The concepts like fuzzy walk, fuzzy path,fuzzy trail and fusion of vertices and distance of fuzzy graph are discussed in this chapter. Thecondition for the existence of fuzzy walk in a fuzzy graph is captured. The edge sequence,composite fuzzy walk, inverse fuzzy walk and reachability of fuzzy graph is introduced . Thenecessary condition for existence of fuzzy path in fuzzy walk is given through fuzzy adjacentmatrix.Various results characterizing fuzzy walk and its varieties with repect to fuzzy graph isgiven. The strength of a fuzzy walk through fuzzy adjacent matrix is established. The equivalencerelation on fuzzy path is interpreted.

Dr Raj BalaImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Government college Barwala (Panchkula)


Over 2000 years old Vedic Maths, was rediscovered by Bharati Krishna Tirathji in 20th Century. Vedic mathematics, which comprises Sutras and sub-Sutras, manifests the coherent and unified structure of mathematics. Vedic knowledge embraced mathematics, logic, physics, astronomy and other disciplines. It generate interest and curiosity in the subject by introducing creativity in intellectual scholar while helping slow-learners grasp the basic concept of mathematics by enhancing their concentration and logical thinking. Vedic Mathematics is also secular as it allows anyone from anywhere in world to practice it and take advantage of the results.

Ms Upasana SamantaImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Senior

Research Fellow at Department of Mathematics,

Jadavpur University Designation : Senior

Research Fellow

The systematic study of selection principles in topology and their relations to game theory and Ramsey theory were initiated by M. Scheepers and in the last twenty years it has become one of the most active areas of set theoretic topology. On the otherhand the idea of statistical analogues of certain types of open covers and selection principles were introduced using actually the ideal of asymptotic density zero sets of natural numbers. So a natural question arises whether one can proceed with the similar investigations using arbitrary ideals instead of special types of ideals. In 1925, one of the most important covering properties was introduced by Hurewicz as a covering property more general than the Lindel?f property. One can see the seminal paper of Miller and Fremlin to know more about this property and its relation with Menger and Rothberger property. Di Maio and Kocinac introduced the statistical variant of the classical Hurewicz property, namely the s-Hurewicz property. Again the ideal analogue of the Hurewicz property was introduced and studied by Das et.al. In this paper we primarily consider the ideal analogue of Hurewicz property and we characterize the ideal Hurewicz property of a topological space X in terms of continuous image of X into the Baire space and also in terms selection principles related to ideal analogues of ? and groupable open covers. We provide the existence of a space with and without I-Hurewicz property. We have investigated some preservation properties related to ideal Hurewicz property. We obtain equivalent condition when a (finite) product space has ideal Hurewicz property. We also characterize the condition that a space without ideal Hurewicz property in terms of cardinality for a certain types of topological spaces.

Dr Chetna MishraImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Integral

UniversityDesignation : Research

scholar

Introduction: Diabetes is characterized by progressive beta cell death or dysfunction mediated by oxidative stress that occurs from gluco/lipotoxicity. Phytochemicals may have protection against the early stage of diabetes mellitus. Thus, aim of this study was to elucidate the effect of Citral isolated from Cymbopogon citratus on streptozotocin induced pancreatic beta cell damage in rats and also see the effect of Citral on adipogenesis via in vivo and in vitro Methods: Beta Cells were treated with the 0.5 mM Strptozotocin (STZ) and various concentration of Citral. Adipogenesis was performed on preadipocytes were isolated from adipose tissues of rats and differentiated into adipocytes in the presence of citral. The effect of citral on expression of Bcl2, Caspase-3, glucose transporter 4 (GLUT4) and AMPK/ACC in adipocytes and beta cell were investigated by western blot. Result: Streptozotocin treated cells showed the increased level of pro-apoptotic proteins (Caspase-3) compared to control, whereas anti-apoptotic protein (BCL2) level was decreased in both adipocytes and beta cells. However, Citral decreased the proapototic protein Caspase-3 and increased BCL2 levels in beta cells and adipocytes. Citral significantly suppressed lipid accumulation in differentiated adipocytes. Furthermore, Citral increased phosphorylation of AMP-activated protein kinase (AMPK), resulting in decreased activity of acetyl-CoA carboxylase in adipocytes and beta cells. Citral also increased the GLUT4 translocation in adipocytes as well beta cells. Conclusion: Results of this study suggest that Citral could protect against pancreatic ?-cell apoptosis and dysfunction and suppress lipid accumulation via stimulation of AMPK activity. Therefore, it may be a potential pharmacological agent for preventing pancreatic ?-cell damage and management of dyslipidemia in diabetes. Key Words: Adipogenesis; AMPK; Beta cells; Citral; Diabetes; Streptozotocin

Mr Tanveer AhmedImage Delegate ID Theme Details


Research

Category : Aerospace Engineering

Organisation : RV College of Engineering

Designation : Student

Nanosatellites are proven to provide economic access to space and multitudinous efforts are undertaken to realize sophisticated missions in them, particularly by academicians and students. Built by Team Antariksh – the student space technology team of RV College of Engineering (RVCE), RVSAT-1 is a 2U Cubesat which houses a microbiological experiment as payload. It has very narrow operating temperature range and is sensitive to temperature fluctuations. Calculation of orbital thermal loads on a nanosatellite is crucial for its success and calculation of orbital thermal loads of RVSAT-1 is studied in this paper. RVSAT-1 is a spacecraft intended to be placed in a polar sun synchronous Low Earth Orbit. It experiences solar, albedo and earth IR as external thermal loads and these are functions of its orbital parameters. Regression and beta angle of the orbital plane is computed for all days of its mission. External thermal loads are minimum in the eclipse region and the eclipse region is dependent on the orientation of the orbital plane with respect to sun. The angular locations at which it enters and exits the eclipse region are determined. With the information of eclipse region for all the computed beta angles, thermal loads at various angular positions are determined. Considering the solar activity and the elliptical nature of earth’s orbit around the sun, six set of heat fluxes, three for hot case and three for cold case are computed at each point. Thermal flux at every location of the nanosatellite mission is obtained. A detailed analysis of the obtained heat flux data lead to forecasting the worst hot and cold case thermal loads that RVSAT-1 would experience during its mission.

Ms SHREESHA MImage Delegate ID Theme Details


Research


Organisation : R V COLLEGE OF ENGINEERING


Nanosatellites are proven to provide economic access to space and multitudinous efforts are undertaken to realize sophisticated missions in them, particularly by academicians and students. Built by Team Antariksh, RVSAT-1 is a 2U Cubesat which houses a microbiological experiment as payload. It has very narrow operating temperature range and is sensitive to temperature fluctuations. Calculation of orbital thermal loads on the RVSAT-1 is crucial for its success and is studied in this paper. RVSAT-1, a spacecraft in Low Earth Orbit experiences solar, albedo and earth IR as external thermal loads and these are functions of its orbital parameters. Regression and beta angle of the orbital plane is computed for all days of its mission. External thermal loads are minimum in the eclipse region and the eclipse region is dependent on the orientation of the orbital plane with respect to sun. The angular locations at which it enters and exits the eclipse region are determined. With the information of eclipse region for all the computed beta angles, thermal loads at various angular positions are determined. Considering the solar activity and the elliptical nature of earth’s orbit around the sun, six set of heat fluxes, three for hot case and three for cold case are computed at each point. Thermal flux at every location of the nanosatellite mission is obtained. A detailed analysis of the obtained heat flux data lead to forecasting the worst hot and cold case thermal loads that RVSAT-1 would experience during its mission.

Ms ishika guptaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : BENGAL

INSTITUTE OF TECHNOLOGY


The increase in freshwater demand in recent years due to industrialization and human needs isleading to a huge depletion in ground water level. The current trend for treatment of waste waterusing chemical coagulants like alum, FeCl2 in treatment plants for sewage and waste water during thepurification process is costly and eco-unfriendly. This excess use of amount of chemical coagulantscan affect human health e.g Aluminium has also been indicated to be a causative agent inneurological diseases. In this project we investigate the possilibility of using biologicalmaterials in place of chemicals for effective purification of waste water. The efficacy and abilityof cyanobacterial species (blue–green algae) Cholerella sp. and Phormidium sp. both individuallyin consortium, and of seeds of Moringa Oleifera to reduce various pollutants from wastewater hasbeen evaluated. Our study revealed that MO seeds can eliminate turbidity from raw materials,maintain pH and is effective in softening of water and also improves and amend sludge which has anoverall impact on pathogenicity of waste water. Cyanobacteria possess high metal absorption capacityand multiplication rate and is photosynthetic which have encouraged the application of thismicrobial biomass in detoxification of effluents and have an edge over conventional wastewatertreatments and provide a favorable condition for removal of heavy metal from environment. Themicroalgae help in the reductions of Biochemical oxygen demand(BOD), total nitrogen(TN), totalphosphorus(TP), chromium(Cr) and total dissolved solids(TDS) of the waste water. Physical, chemicaland microbial parameters like colour, pH, temperature, suspended solids, dissolved solids, DO,Chloride, BOD and coliform from wastewater and from treated water. Analysis of contaminated wastewater yielded the following data at 30ºC: pH – 6.1, BOD- 209mg/lt, DO-2.2 mg/lt, organicphosphate- 29mg/lt, inorganic phosphate- 25mg/lt, coliform- positive while the treated water data at31ºC is pH- 6.8, BOD- 269 mg/lt, DO- 2.1 mg/lt, organic phosphate- 24 mg/lt , inorganic phosphate-24 mg/lt, coliform–negative. The results indicate that use of the above mentioned biomaterial maylead to a cost effective, ecofriendly waste water treatment system and for recharging thegroundwater.

Ms Aarohi MudholkarImage Delegate ID Theme Details


Research


Organisation : SRM Institute of Science and Technology


Acoustics is an integral constituent of most of combustion processes. While combustion advancements have revolutionized human life, acoustics induced combustion also represents a dominant form of instability. Thermo-acoustics, as an intense area of scientific research, covers a wide range of applications viz., industrial (electricity generation), transportation (jet and space propulsion), engineering (system efficiency and operations) and scientific research. The presence of such inept working systems with instability is likely to result in significant loss of resources, infrastructure, property, mankind, nature, with huge amount of money being spent on research activities. Appreciable work has been done before however; the heterogeneous nature of the problem has prevented comprehensive understanding. Thus, the need to investigate and characterize the acoustics imbibed combustion processes to suggest better combustion alternatives/ enhance effectiveness and to minimize the resultant hazards. Present work, attempts to resolve the low effectiveness of combustion systems by classification of thermal acoustics and related major hazards. Systematic experimentation will be carried out to explore the phenomenon of energy transition in combustion with acoustics. A simple experimental setup will be upraised, comprising of butane cylinder with nozzle, igniter, facility for acoustic measurement and optical shadowgraphy. The exploration will be carried out for varying fuel mass flow rates, L/D ratios, material of tubes, interspace distance and counter acoustics impingement. The results will be observed with acoustics measurement, along with type and structure of flames. The work is primarily motivated by the need to have technologically enhanced combustion understanding and for fire safety applications. The specific objectives of the work are: (a)To investigate the presence of acoustics in combustion process under different geometrical, design, parametrical variations. (b) To investigate the role of key controlling parameters. The results are likely to be very useful for practicing combustion in institutions, observatories, labs, along with wide range of practical, functional and engineering applications. The significance being, the testing, validation of conventional systems and designing of the efficient and safer futuristic propulsive systems.

Ms Pallabi ChatterjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Amity Institute

of Biotechnology Designation : M.Sc. student

Nanoparticle is defined as the particle whose size should be less than 100nm. It is widely used in clinical medicine for the betterment of drug delivery. Drugs, antibiotics acts against many diseases which are caused by pathogenic microorganisms, many drugs have their side effects inside the host. If nanoparticles are conjugated with this drug, then only the drug will bind to the affected organ, and will not harm other cells in the host. In this experiment, nickel nanoparticle was synthesised by using nickel chloride salt with Calotropis gigantea leaf extract. Firstly, the Calotropis leaf extract was made by washing the leafs, calculating 60 g of dry weight of it which was later mixed with the 1M NiCl2 solution and then incubated in the shaker at 90 RPMI for 24 hours. The spectrum of the solution (100 microL nanoparticle in 2ml distilled water) was checked which gave the pick at 240 nm. A total of 3 petri plates were taken which contain autoclaved nutrient agar media. Pseudomonas aeruginosa (strain No. ) was spreaded onto the 3 plates. The minimum lethal concentration of the nickel nanoparticle was checked by performing an assay where different volumes like 10microL, 20microL, 30 microL, 40 microL, 50 microL, 60microL and 70microL were added to the 2 petri plates. The minimum lethal concentration of the nanoparticle is, which can be used for the synergistic assay. Tetracyclin is used here as the semisynthetic antibiotic. On the other plate, 4 wells were made and nanoparticle, antibiotic, nanoparticle (100 microL nanoparticle in 2ml distilled water) conjugated antibiotic and water (as control) is added separately in the each well, then it is incubated at 37 degree celcius for 24 hours. The result of this experiment came excellent. Then zone of inhibition are 28mm, 13mm and 32mm by the nanoparticle, antibiotic, nanoparticle respectively. The control zone gave 0 mm. From this experiment, it is concluded that only antibiotic or nickel nanoparticle cannot kill bacteria sufficiently but the conjugated antibiotic-nanoparticle can do that better. It is because of the antimicrobial activity of Calotropis plant; this plant also secrets some toxic secondary metabolite which reduce the size of nickel chloride and nickel nanoparticle having high stability was synthesised. This nickel nanoparticle when conjugated with tetracyclin it gives the best result against Pseudomonas aeruginosa. Keywords : Nickel nanoparticle, tetracycline, Pseudomonas aeruginosa, Calotropis gigantea.

Ms SUPREET KAURImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR- NPLDesignation : RESEARCH

SCHOLAR

Air pollution is one of the severe problems that the world is facing today. Increase in number ofindustries and automobiles are continuously adding pollution gases and particulate matter (PM) tothe environment. PM represents a complex mixture of organic and inorganic substances of varyingshape and size and is of serious concern in respect of plant health. In plants, deposition of PMoccurs on the upper surface of the leaf and to some extent on the lower surface. In the presentstudy, the experimental site lies in the circuitous of road having a variety of flora withcontinuous high vehicular traffic. The study analyses the morphology and elemental composition ofthe Dry Deposited PM (DDPM) over the tin substrate fixed at the leaf surface, carried out usingField-Emission Scanning Electron Microscopy (FE-SEM) coupled with Energy DispersiveSpectrophotometer (EDS) for some roadside plant species. Microscopic examination revealed that theDDPM existed in several different geometries including irregular, amorphous, elongated, flaky, rodshaped, sticky and crystal appearance with rough and smooth surfaces. Few of them exhibit uniquecharacteristics such as star-shaped, elliptical and granular shape. Total ~ 3,509 particles havebeen analyzed using microscopic techniques. A frequency distribution graph was plotted based on thesize of particles. Particles of size range stomata size, particles belonging to all size categories (i.e. 20?m) caninterfere with stomatal functioning causing closure of the leaf stomata and lower the rate oftranspiration. Elemental composition of few individual particles through EDS analysis displayed thatC was present in maximum proportion in all species with Mg, Al, Si, Fe and Na in minor quantitieswhile N, F and S were also found in trace amounts. Respective particles have their discrete as wellas combined effects on the functioning of leaf. Major compounds such as Sulphates, C (like Blackcarbon, elemental carbon and organic carbon), oxides of Nitrogen and Fluorine show profound effectson the plants. It can be inferred that PM deposition on leaf affects the functioning and, hence,reduce the growth and yield of plants.

Mr Ashutosh JhaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Delhi

Technological UniversityDesignation : Student

Cadamba belongs to Rubiaceae family having pharmacological and therapeutic properties. Over the pastseveral centuries a significant score of vegetation is used for a variety of medicinal purposes ofwhich India, China and Egypt have actively using medicinal plants for the treatment of variousdiseases which were incurable. There are a number of ancient therapeutic measures based on medicinalplants that have been developed in India to cure several ailments such as diabetes, cardiovasculardisorders, cancer and liver damage. The phyto-chemical analysis of the plants is very importantcommercially and has great interest in pharmaceutical companies especially when less than 2 % havebeen commercialised due to lack of a suitable model system for the production of the new drugs forcuring of various diseases. Therefore, the present study was undertaken to investigate thebiochemical properties of fruits of N. Cadamba. The N. Cadamba fruit was analysed for elements,vitamins and functional groups, mature fruit was used for the study. The elemental analysis wasassessed by ICPMS, chemical composition was done with FTIR analysis, nutritional value was analysedby HPLC, and surface was examined by SEM. The results of the phyto-chemical analysis showed that theminerals, vitamins, steroids, phenol group, structure, alcohol, amides, secondary amides flavonoidsand alkaloids were found to be present. The N. Cadamba has various properties of antioxidant,anti-cancerous anti-diabetic and nutritional properties based on elemental and HPLC analysis whichhas shown the presence of some important elements such as Au, Ag etc. The potential of this plant(fruit, leaves, stem, roots etc.) extract is still not very well known and requires more research.

Dr Sidhharth SirohiImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation :

Bhasharachaya College of Applied Sciences, University of

DelhiDesignation : Assistant

Professor

The present study aims at novel synthesis of hybrid Ag/SiO2 nanostructures with well defined spherical and triangular silver nanoparticles. The dye degradation behavior of the nanostructures was compared to analyze the effect of shape and hence surface plasmon resonance on the photocatalysis. Further the effect of porosity of silica nanoparticles was also investigated. Dyes have extensively been used in textiles, food, furniture and paint etc. These synthetic dyes, having complex aromatic structures are stable and non-biodegradable. The intentional dumping or accidental discharge of dye-contaminated water into the environment creates considerable health hazards. The chemical treatment of dyes is not economically viable. Biological treatment is a better solution but it is quite tedious due to requirement of a large area of land and cumbersome operation. Use of adsorbents, is a simple and effective way for decontaminating dye pollutants. Various adsorbents including silica, zeolite, charcoal, carbon have been explored by researchers. Yellow and Blue AgNPS were attached on the surface of amine functionalized silica to prepare Ag decorated SiO2 nanoparticles. The photocatalytic properties of the mesoporous SiO2/Ag were investigated for degradation of methylene blue and compared with that of non-porous SiO2/Ag nanoparticles and pristine Ag nanoparticles. Mesoporous SiO2/Ag nanoparticles showed remarkable improvement in degradation of methylene blue as compared to non-porous SiO2 and pristine Ag nanoparticles respectively. Blue Ag nanoparticles, owing to their better charge carrier generation and enhanced surface plasmon resonance, exhibited better photocatalysis performance as compared to yellow Ag nanoparticles. Large surface area and high porosity of mesoporous silica nanoparticles along with surface plasmon resonance of blue Ag was resulted in significant improvement in photocatalysis of SiO2/Ag composite nanostructures. References: 1. Sirohi, S., Singh, A.,Dagar, C., Saini, G., Pani, B., Nain. R. Appl Nanosci. 2017, 7:633-643. 2. R. Nain, S. Dobhal, P. Bidaliya, G. Saini, B. Pani, S. Sirohi. RSC Adv. 2018, 36:20287-20294.

Mr BALAKRISHNAN ARUMlUGAMImage Delegate ID Theme Details


Research

Category : BiologyOrganisation :

K.S.Rangasamy College of Arts and Science


Polyherbal Tooth Powder A Possible remedy for Dental Caries caused by Staphylococcus aureus Balakrishnan Arumugam*, K.Pavithra and G.Saravanan

Department of Biochemistry, Centre for Biological Sciences K.S.Ramgasamy College of Arts and Science (Autonomous), Tiruchengode, Namakkal-637215, Tamilnadu, India E-mail: [email protected]

ABSTRACT Plants are habitually used in the prevention and treatment of several diseases in most part of the world and it is still widely practiced today. Oral and dental hygiene is the primary and vital component to lead a healthy life. Poor and improper hygienic practices may lead to teeth and gum diseases, dental cavities, and plaque etc., There has been constant effort to focus on interception and correction of disease entity but today our horizon has broadened the approach and goal remains to prevent the disease process rather than to correct it. The objective of the present study was to formulate polyherbal toothpowder using commonly available medicinal plants which includes neem leaves, acacia bark and Kedrostis foetidissima (appakovai) and to evaluate its medicinal properties. Polyherbal toothpowder is subjected to phytochemical analysis and tested for its antimicrobial activity at different concentrations (50 - 500mg/ml) by agar well diffusion method. Polyherbal tooth powder exhibited significant antimicrobial activity against Staphylococcus aureus strains with a maximam zone of inhibition at 500mg/ml concentration which may be due to the presence of different phytoconstituents in polyherbal tooth powder. Totally 11 active phytoconstituents have been identified in methanolic extract of polyherbal tooth powder by GCMS analysis. Physiochemical properties evaluated using standard parameters ensured the quality of the formulated polyherbal tooth powder. The results of the study demonstrated that the formulated polyherbal tooth powder have promising antimicrobial activity that supports the traditional usage of plants as therapeutics and may be safer and effective approach towards preventive oral care.

Keywords: Oral and Dental Diseases, Staphylococcus aureus, Polyherbal Tooth Powder, Oral Hygiene

Mr MANOJKUMAR GODHANIYAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DEPARTMENT

OF BIOSCIENCESDesignation : RESEARCH

FELLOW

The Winogradsky column is a unique microbial ecosystem that has several advantages for use as amodel system to study microbial dynamics, interaction, and diversity. Pesticides are stablecompounds and they enter the aquatic ecosystem through the agriculture runoff. The evaluation ofnature and degree of harmful effects produced by a toxic substance in the aquatic organisms areevaluated by toxic tests. Amlakhadi canal, flowing through Ankleshwar (Gujarat, India) has impingedwith various xenobiotic compounds, released by industrial discharges, over last many decades.Twenty-five bacterial strains capable of phenanthrene degradation were isolated from sediments ofAmlakhadi canal. Because Amlakhadi receives the industrial effluents that constitute the majorpetrochemical, dyes and paints industries and eventually disposed of in the river Narmada.Monocrotophos is an organophosphate insecticide. Monocrotophos is principally used in agriculture,as a relatively cheap pesticide, but it is toxic to human and birds. Metagenome was successfullyisolated from the upper and lower zone of winogradsky column by using HiPurATM Soil DNA PurificationKit(MB544) and quality assessment was done by using Qubit fluorometer. Illumina MiSeq platform basedsequencing and community metagenomic analysis were done by ONE CODEX, Megan and METAGENassistrevealed rich microbial diversity. The upper zone of winogradsky column contains more microbialdiversity. The comparative analysis demonstrated a significant difference in the microbial communityin different zones of the Winogradsky column. The predominant phyla detected in the study wereProteobacteria, Firmicutes, and cyanobacteria. The result indicates the complex communityinvolvement in biodegradation of pesticide monocrotophos.

Mr Ashish BhattImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : No fellowshipDesignation : P.hD Scholar

All bodies above the absolute zero (0 K, - 273.15°C) emits an electromagnetic radiations proportional to its temperature. Infrared temperature measurement devices define temperatures through the infrared radiation emitted by the object, measured without contacting the object. Infrared thermometers for non-contact temperature measurement have wide-spread applications in industrial processing and research. The IR region of electromagnetic radiation lies between wavelengths of 0.7 to 1000 ?m. In the present paper, we have presented a detailed study on oxide based pyroelectric infrared thermal detectors, such as, Ba(1-x)SrxTiO3, Sr(1-x)BaxNbO3, LaTiO3, LiTiO3, KNbO3, SrTiO3 etc. and discussed the various parameters of an IR detector such as responsivity, noise equivalent power, figure of merit and specific detectivity. Properties viz. dielectric constant, losses, volume specific heat, pyroelectric coefficient and thermal conductivity of these materials for IR detector have been discussed. These oxide based pyroelectric detector materials will be used for developing IR sensor at low temperatures and will be standardized by fixed point blackbodies developed at CSIR-NPL. CSIR-NPL is National Metrology Institute of India and has IR Thermometry standardization facility from 30 oC to 3000 oC. Based on this study, the CSIR-NPL roadmap on the development of IR detector for thermometry application is also proposed.

Ms KUMUD NIGAMImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : AMITY

INSTITUTE OF BIOTECHNOLOGY, AMITY

UNIVERSITY UTTAR PRADESHDesignation : PhD Scholar

Interplay of GSTT1 gene and smoking in risk modulation of Oral Pre Cancer Kumud Nigam*, Somali Sanyal Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow-226028, India (AIB Communication No.AIB/RA/2019/282) *[email protected] [email protected] Abstract: Many polymorphic genes that code enzymes involved in carcinogen biotransformation have been reported to be associated with development of cancer. GSTT1 gene that code phase II enzyme belongs to the glutathione S-transferases (GSTs) family and seems relevant for the susceptibility to oral diseases as it detoxify carcinogenic tobacco smoke to its excretal form. However, an individual's physiological responses to environmental stimuli can be modulated by genetic variations of carcinogen metabolizing genes like GSTT1. Oral precancerous lesions such as Leukoplakia, Lichen planus and Oral Submucous Fibrosis are early indicators of damage to the oral mucosa and tobacco smoking is one of the known causal factors for its development. This study evaluated the interplay between GSTT1 gene and smoking in risk modulation of pre oral cancer in North Indian population. For this 138 subjects of pre oral cancer and 300 healthy controls been genotyped for GSTT1 polymorphism with PCR method. Genotype frequency was analyzed by chi-square test and strength of associations by odds ratio with 95% confidence intervals. Our results showed that absence of GSTT1 gene increases the risk of pre oral cancer by more than 8 times (P-value= 0.0001*, OR= 8.90, 95% CI 4.65-17.03) in non smokers. While smokers who lack GSTT1 gene were at 12 fold increased risk for having pre oral cancer (P-value= 0.0003*, OR= 12.15, 95% CI 2.67-55.27). In conclusion, our results indicate an interaction of GSTT1 gene and smoking in modulation of risk for pre oral cancer. Keywords: Pre oral cancer, Smoking, GSTT1.

Dr Alka SharmaImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Shri guru

Gobind Singh College Sector 26 Chandiagrh


Nanotechnology can enable sensors to detect very small amounts of chemical vapours. Cancer nanotechnology is a branch of nanotechnology concern with the application of both nanomaterial and nanotechnology approaches to the diagnosis and treatment of cancer. Among the newly developed Nano medicine and Nano devices such as quantum dots, nanowires, nanotubes, Nano cantilevers, Nano pores, Nano shells and nanoparticles are the most promising applications for various cancer treatments. Nanoparticles loaded with drugs can be designed to overcome the biological barriers to improve efficacy while reducing morbidity. So, nanotechnology is on the same size and scale as disease. A nanorobot can grab a cell and repair it. This will allow us to cure diseases that have never been cured before.

Dr Dileep Kumar GopaluniImage Delegate ID Theme Details


Research

Category : Software Engineering

Organisation : KKR & KSR INSTITUTE OF

TECHNOLOGY & SCIENCESDesignation : Associate

Professor

The main purpose of this project is to design and development of crop protection system against floods and heavy rains to protect the crop or fields from heavy rains. Main motivation behind this work is most of the farmers are attempted to suicide because of lost their fields in many situations like floods, heavy rains, unexpected natural disasters, wind storms, virus effected to the crops. In this proposal, we considered floods or heavy rains because in these two situations farmers lost can’t be recovered. So here we proposing a crop based protection system to protect the field. In this proposal field comprises of some scales, sensors, and digging machines were inserting inside the field and power hub is designed at central location this will control the whole system and it sends the notifications to users (farmers).

Dr VEERASWAMY AMMISETTYImage Delegate ID Theme Details


Research

Category : Software EngineeringOrganisation : St.Ann's College

of Engineering & TechnologySt.Ann's College of

Engineering & TechnologyDesignation : Associate

Professor

Aquaculture has been a quickly developing industry on account of critical increments popular forfish and fish all through the world. Its financial significance is expanding monetarily. Aquaculture- otherwise called fish or shellfish cultivating - alludes to the reproducing, raising, andgathering of plants and creatures in a wide range of water conditions including lakes, streams,lakes, and the sea. During the hot sunny days, most of the oxygen levels in the water are decreasingrapidly. The oxygen levels in the water plays a crucial role in the aqua farming. So, the farmers,to increase the oxygen levels, used to rotate the aerators which will increases the oxygen levels.They use to rotate aerators without any specific time period due to this a lot of electricity iswasted to operate the aerators. To avoid this waste of Electricity, we are going to sense the oxygenlevels, temperature levels and ph levels. Based on the threshold levels of oxygen the aerators areoperated. There by the electricity bill is reduced. The farmer needs not to stay at the ponds forthe hours and the farming cost will be reduced and also get good profits to farmers.

Mr Shachindra DubeyImage Delegate ID Theme Details


Research


Organisation : Jabalpur Engineering College, Jabalpur

(M.P.)Designation : Lecturer

Crime rate is increasing now-a-days. Here we introduced a system by which crime rate can be reduced.Crime data must feed into the system. We introduced data mining algorithm to predict crime. K-meansalgorithm plays an important role in analyzing and predicting crimes. K-means algorithm will clusterco-offenders, collaboration and dissolution of organized crime groups, identifying various relevantcrime patterns, hidden links, link prediction and statistical analysis of crime data. This systemwill prevent crime occurring in society. Crime data is analyzed which is stored in the database.Data mining algorithm will extract information and patterns from database. Clustering will be donebased on places where crime occurred, gang who involved in crime and the timing crime took place.This will help to predict crime which will occur in future. Admin will enter crime details into thesystem which is required for prediction. Crime incident prediction depends mainly on the historicalcrime record and various geospatial and demographic information.

Ms Shubha MishraImage Delegate ID Theme Details


Research


Organisation : LNCT BhopalDesignation : Assistant

Professor

In Today's era of the internet, every individual is connected on the go. We all have access to hugechunks of information available in the form of structured semi-structured, unstructured data. Theunstructured data is available in huge amounts but this unstructured data can be used throughstatistical analysis to derive useful information from it. The multiplexes based on the user ratingdetermine whether a movie should be continued in the cinema or not. So, the movie sentimentalanalysis holds huge importance for these multiplexes because if the movies have good user reviewsthen more viewers are expected to come to theatres which will generate higher revenues to themultiplexes. This paper introduces an approach to sentiment analysis which uses Keras and sequentialmodel.

Dr Mani PadmanabhanImage Delegate ID Theme Details


Research


Organisation : VIT, Vellore Designation : Assistant

Professor

The growing usage of software based products are coupled in the day to day human life. The softwareengineering technology can be more eye catching among the artificial intelligent based softwaredevelopers. The artificial intelligent systems such as human machine interaction process aredifficult to identify the pre-conditions during the development. Re-engineering is essential for theAI based systems. Regression testing has assured the quality of products during the re-engineeringprocess of AI systems. The test cases are core component in the regression testing. Test caseprioritization and selection is a major activity to reduce the time during the regression testing.Many test case selection techniques have solve the problems in the regression testing, However thetechniques seems to have much focus on reducing the number of test cases. In this paper propose atest case prioritization based control flow diagrams. In the test case selections are controlled bysimulation invocation relationship. The proposed simulation invocation algorithm identified thesimulations to be affected during the re-engineering process. In the next process identified thesimulations and converted into stack array. The proposed prioritization algorithm produced the testcases based on the fault coverage criteria. The approach has been validated with three artificialintelligent based systems during the regression testing. The comparative analysis shows thatproposed approach are well suitable for artificial intelligent systems during the re-engineering interms of average percentage of fault detected values.

Ms Himanshi DewanganImage Delegate ID Theme Details


Research


Organisation : Amity University, ChhattisgarhDesignation : Student

DATA MINING.Himanshi Dewangan.Bachelor of Technology in Computer ScienceAmity University Chhattisgarh, [email protected]

INTRODUCTION. Data mining is utilized to identify and establish a association between large datasets to seek out a solution to aproblem through analysing information. There area unit several tools and technique in knowledge data processing realize the applying in varied field of analysis, statistics, genetics and promoting.Rewards of Data Mining?Data Mining helps in selling and retail enterprises to check customers behaviour.?Organisations into banking and money business will get data about customers historical data and financial activities ?Helpful to forecast future trends and decision making.Drawbacks of Data Mining?Privacy issues?Safety issues? Information mined from data mining can be misused.Main Purpose of Data Mining Basically, the data gathered from data processing helps to grasp hidden patterns, future trends and behaviours and permitting business to require selections.Technically, data mining is computational process of analysing data, from different perspective, dimensions, angles and categorizing/summarizing it into meaningful information. Data mining can be applied to any type of data e.g. Data Warehouses, Transactional Databases, Relational Databases, Multimedia Databases, Spatial Databases, Time-series Database, World Wide Web.Data Mining ApproachesData mining can take various approaches and build totally different models relying upon the sort of information concerned and also the objectives.•Rules of association•Clustering•Classification•Regression•Optimisation•Web and Text Mining

Prof Sathis KumarImage Delegate ID Theme Details


Research


Organisation : Saranathan College of Engineering


Business level assistance can be executed by middleware in big business frameworks to improveinteroperability and furthermore gives the straightforward usage of customer and server process. Toimprove the exhibition of B2B (Business to Business) and B2C (Business to Consumer) as far as bigbusiness wide Service Oriented Architecture (SOA), we have to have middleware interoperabilityparticularly with delegate designing specifically CORBA (Common Object Request Broker Architecture)proposed by Object Management Group ORB programming named ORBeline is accessible as CORBA protest.Unmistakable models for customer server interchanges have just been created and executedspecifically Handle Driven ORB (H-ORB), Forwarding ORB (F-ORB), Process Planner ORB (P-ORB), andAdaptive ORB (A-ORB). This paper concentrates how to improve the presentation of theinteroperability in Process Planner ORB (P-ORB) and Adaptive ORB (A-ORB) as for customer servercooperation in an N-level engineering alongside multithreading condition. The strategy calledinteroperable support learning procedure and how it will in general be used for improving thepresentation of interoperability is examined. The outcome gives the framework conduct especially theimpact of message measure, between hub postponements, lethargy and flexibility ofsolicitation/reaction administration times for the P-ORB and A-ORB design are investigated.

Dr Varun GuptaImage Delegate ID Theme Details


Research


Organisation : Chandigarh College Of Engineering & Technology (Degree Wing)Designation : Associate

Professor

Artificial Intelligence (AI) has revolutionized the healthcare industry by employing complexalgorithms, big data and computing power to emulate human intelligence. AI technique specificallydeep learning allows more accurate and faster diagnosis of diseases by examining thousands ofpatient instances. Manual disease diagnosis by healthcare experts is not just time consuming andtedious but also more prone to error. This necessitates the need for Computer Aided Diagnosis (CAD)systems. Such systems can assist healthcare experts in speedy diagnosis where mass screening ofpatients is required. Deep learning coupled with medical imaging helps to analyse images of varioushuman body parts for early detection of diseases like lung cancer, breast cancer, diabeticretinopathy, brain tumour etc. Diabetic Retinopathy (DR) is a very common microvascular complicationof diabetes and a main reason for blindness globally. We have developed a deep neural network systemfor detection of DR disease which shows high accuracy gains over the traditional approaches. Theproposed model when trained on publicly available MESSIDOR achieves 100% overall accuracy for binaryclassification and 99.16% for multistage classification without over fitting of the model. Thisshows an overall improvement in accuracy by about 3% for binary classification and more than 6% formultistage classification compared to the state-of-the-art methods available in the existingliterature. The proposed system can further be extended to determine the problem areas by employingsemantic segmentation (pixel wise segmentation) of DR images.

Ms Julika KImage Delegate ID Theme Details


Research


Organisation : Azad Girls MAtriculation higher Secondary School


Augmented Reality Code is an next generation of QR & barcode, by using AR code we can embed 3d models ,videos and GPS data. In this project , I have embed videos in Samacheer Kalvi book content (Tamilnadu TextBook) using AR concept by UNITY(open source Software). It will used to all students, they easily learn the content by using their Smartphone’s (Android, IOS & Windows).I have inspired the smart board in my school, they using the System, Projector and keyboard etc. Now a day’s more than 80% of peoples using Smartphone’s. I have embed the videos in Samacheer Kalvi book content (Tamilnadu TextBook) using AR concept by UNITY & Android Studio(open source Software). If it is implemented, it is useful for all students, parents and teachers. So we can use our textbooks into smartbook using smartphones without smart boards.

“Augment Reality act as bridge between virtual world and real world” For this implementation, only Smartphone & internet needed for this concept

Requirements For Development(Unity Software,Android Studio) Requirements For End-user:(Smart Phone with Gyro or ARCore supported)

Mr stephen sagayaraj arokiarajImage Delegate ID Theme Details


Research


Organisation : Jai Shriram Engineering college


Abstract: Biometrics plays an important role in military applications. The recent advancement ofbiometrics is gait recognition. The gait is capturing the movement of humans with the unobtrusivemethod. The proposed methodology background is Chennai metropolitan city police installed the camerasupported with Artificial Intelligence which identifies the person who made unlawful violence whenthe person crosses the camera. The drawback is the camera cannot identify the corresponding personwhen the person camera is covered. To recover this proposed methodology measures gait (HumanMovement) for the image captured by CCTV footage. The proposed method is initially checked bySRILANKAN BOMB BLAST issue CCTV footage which measures the movement of terrorist recorded in-camera.The features like movements, actions, hand swings and measurements of their body parts. To implementthis, different image processing methodologies and machine learning techniques such as KNN, ANFISare followed to recognize the gait of an unauthorized person. This methodology is implemented in aChinese government organization to recognize the terrorist in Chinese military base. Thismethodology proposes the identification of humans using gait recognition. KNN gives 86% accuracy andANFIS gives 70% accuracy.

Mr Trilok SainiImage Delegate ID Theme Details


Research


Organisation : DRDODesignation : Scientist

Nature inspired algorithm in computing system for routing solutions

Trilok Kumar Saini* and Subhash C. Sharma Defence Electronics Applications Laboratory, DRDO, Dehradun, India, Indian Institute of Technology, Roorkee, India [email protected]

Abstract: Applying the nature inspiration in the computing systems provides a new dimension to solve the complex problems. There are many nature-inspired algorithms like ant colony optimization, bat algorithm, bee colony optimization, cuckoo search, fisheye algorithm, fly algorithm, and firefly algorithm, etc. that mimic the behavior of the natural species. Swarm intelligence is the stimulating collective behavior of the natural entities, and some of the self-organized natural actions are bird flocking, animal herding, and bacterial growth, etc. Genetic algorithm is also one of the forms of the natural evolutional phenomenon and is inspired by the genetic process. We focus on diversified techniques and the algorithms that take inspiration from nature. If finer details of the natural events are analyzed, many of these reflect the high possibility to resemble with the computing processes in the real world. We consider the natural inspiration in finding the routes in the decentralized network of the mobile nodes, where mobility and the network formations are dynamic, and the resources are limited. In this process of proposing the routing algorithm, we consider that nodes resemble with the living entities. Network conditions are dynamic as the real environment, and the algorithm aims to find the route to the destination. We also take into consideration to maintain connectivity with the intended destination. In concluding remarks, we can state that by utilizing the natural process and the advanced computing techniques, we can develop the new algorithms and can apply in diversified fields to find the optimized solutions to the problems.

Mr Abdul AleemImage Delegate ID Theme Details


Research

Category : Software EngineeringOrganisation : Dr harisingh Gour

Vishwavidyalaya(A central University)

Designation : Research Scholar

Abstract: In the present scenario, the healthcare system is producing huge amount of data in theform of patient records day by day due to rapid development in technologies which has facilitatedthe healthcare system. Due to the technology development all the information collected and stored indigital form with different variety of data such as doctor’s prescriptions, medical diagnosisreport, images etc. Big data analytics has been widely adopted by many organizations to obtainuseful information from the large and variety of dataset. In order to producing vast amount ofpatient health data with high volume, high velocity and high variety of data is forming big data andthose data become challenging task to process and manage it. The challenges can be processing time,implementation cost, transportability, privacy and security. Big data has basic threecharacteristics which are known as 3Vs, in 3Vs first V refers to Volume, second V -Velocity, andthird V- Variety. Actually big data as a gathering all 3Vs and elaboration help to a person to find,accept, and bear a new technology. The big data analytics has ability to handling the complex datawhich is formed by different resources to provide distinctive characteristics of information and itincludes secure, store, research, share, analyze the healthcare data. Big data analytics hasopportunities that can be perform predictive analytics for present condition and future events also.The vast availability of electronic health record offers an opportunity to apply predictiveanalytics technology to improve the practice of medicine and also potentially novel risk factors. Inthis paper, we have addressed current challenges and its solution opportunities which are arisingthrough complex health dataset and furthermore we have introduced a predictive analytics model as asolution opportunity to process these complex data by using big data analytics algorithms.

Mr Vivek ShuklaImage Delegate ID Theme Details


Research


Organisation : DR C V Raman University


Social media has become the most widely used communication and interaction tool Between people overthe past few years. Direct interaction between people is decreasing as people tend to communicateindirectly through smart phones. Thus, it is quite difficult to recognize person’s personality.However, what’s written in social media might help us To get the information needed as peoplespend much time checking social media and Expressing their feelings and thoughts through statuses,comments, and updates. Face book has the largest users reaching 1.8 billion. Now Days in the modernworld social media has become popular. The same is also seen among the people wanting to promotetheir products. Opinion mining and sentiment analysis can be said to have brought in a large amountof interest in present day studies. This is due to the difficulties in the study of trendinganalysis. Therefore, the early work occurred at the document level and by applying different methodsused for classifying a document‘s polarity. This can be done for positive, negative or neutralemotions at any scale. One procedure to yield knowledge is opinion mining. The same can be said forthe opinions of people sharing on social websites, blogs, groups and comment boxes. Opinion mininguses text mining and natural language processing procedures so that a computer can take in theexpression of emotions. Moreover, it is helpful in bringing out the sentiment and emotionalexpressions from unstructured text and providing the best method to classify a given sentimentanalysis. Face book because it is a public social network where users can complain easily about thethings they don't like by me.

Mr Akash PimpalkarImage Delegate ID Theme Details


Research


Organisation : Pillai College of Engineering,New PanvelDesignation : Student

India being an agro-based economy, farmers experience a lot of problems in detecting and preventing diseases infauna. So there is a necessity in detecting diseases in fauna which proves to be effective and convenient for researchers Major economic and production losses occur because of diseases on the plant. Nowadays there are several diseases seen on the plants. For increasing production and quality it is important to control such harmful diseases. For controlling such diseases it is necessary to detect a specific disease. In our country many farmers are not so educated to get correct information about all diseases, they require expert advice. But it is impossible for an expert to reach each farmer. Even if they got an expert, the expert uses naked eye observation. But naked eye observation has very little accuracy. We introduce here a new approach based on image processing for detecting plant leaf diseases. The goal is to detect, identify, and to accurately quantify the first symptoms of the disease. Plant disease is caused by bacteria, fungi, viruses, etc. of which fungi are a main disease-causing organism. The proposed system is a very sensitive and accurate method in the detection of plant diseases, which will minimize the losses and increases the economical profit. It includes the following steps in that, image acquisition, image pre-processing, features extraction, and neural network-based classification

Ms Nitigya SambyalImage Delegate ID Theme Details


Research


Organisation : Punjab Engineering College

Designation : PhD scholar

Artificial Intelligence (AI) has revolutionized the healthcare industry by employing complex algorithms, big data and computing power to emulate human intelligence. AI technique specifically deep learning allows more accurate and faster diagnosis of diseases by examining thousands of patient instances. Manual disease diagnosis by healthcare experts is not just time consuming and tedious but also more prone to error. This necessitates the need for Computer Aided Diagnosis (CAD) systems. Such systems can assist healthcare experts in speedy diagnosis where mass screening of patients is required. Deep learning coupled with medical imaging helps to analyse images of various human body parts for early detection of diseases like lung cancer, breast cancer, diabetic retinopathy, brain tumour etc. Diabetic Retinopathy (DR) is a very common microvascular complication of diabetes and a main reason for blindness globally. We have developed a deep neural network system for detection of DR disease which shows high accuracy gains over the traditional approaches. The proposed model when trained on publicly available MESSIDOR achieves 100% overall accuracy for binary classification and 99.16% for multistage classification without overfitting of the model. This shows an overall improvement in accuracy by about 3% for binary classification and more than 6% for multistage classification compared to the state-of-the-art methods available in the existing literature. The proposed system can further be extended to determine the problem areas by employing semantic segmentation (pixel wise segmentation) of DR images.

Mr Pardeep SinghImage Delegate ID Theme Details


Research


Organisation : Jawaharlal Nehru University New-DelhiDesignation : Research

Scholar Computer science

With the spread of digital technology, social media sites like Twitter, Instagram, Facebook, etc.,made information exchange among people faster and easier. Being a platform of social interaction, Itbecomes vulnerable for many instances like political campaigning, opinion analysis, offensivelanguage, trolling to target individuals or groups of individuals. Hence it becomes worrisome forthe social providers, security agencies and government to handle such situations. Our work aims toanalyze the dark side of social media content: identification and categorization of offensivelanguage, hate speech in social media, rumor propagation with the help of Machine Learning, DeepLearning and Natural Language Processing techniques. We perform our experiments on Twitter benchmarkdatasets for evaluating the performance of models.

Ms Kritika SharmaImage Delegate ID Theme Details


Research


Organisation : AMITY University


"Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity."[1]. Exhausting & round the clock tasks of today’s era leave no time for self-care. A study conducted by Godrej Interio reveals that over 93 percent of Indians are sleep deprived. Research indicates that about 89% of the aged people are likely to live independently and about 80% of the them older than 65 suffers from at least one chronic disease which indeed is a result of lack in continuous and comprehensive healthcare. Hypertension, being the most widespread chronic disease, ranges from 20-40% in urban adults and 12-17% among rural adults [2] and 33% of total population [3]. 50 million people suffering from type-2 diabetes [4], about 45 million people suffer from coronary artery disease and 35.9% deaths are estimated due to this by the year 2030[5]. The proposed methodology is all about low energy, wireless, wearable, non-invasive and low-cost body vitality sensors for temperature, blood-pressure, breathing index, heart rate, pulse rate, sleep time and stress levels being attached in wearable devices. IoT allows seamless interactions among different types of devices and involves many kinds of cheap sensors (wearable, implanted, and environment). The proposed paper is a study on the existing works in wearable BSN (Body Sensor Network) based on IoT and futuristic approaches for health care. Delayed knowledge about or response to health issues such as blood-pressure, heart and pulse rates lead to chronic diseases in long run. The paper thereafter, consists of a machine learning based approach to come up with quick first-aid prescriptions at LPU (Local Process Unit) accompanying existing. The essence of this paper is to create a comfortable assistance. When one aim for a healthy and result oriented population, a conducive ambiance for complete continuous and comprehensive surveillance and supervision needs to be created in conducive manner. The objective of ‘conduciveness’ is achieved with the help of ornaments like illusory for wearable body sensor network based devices.

Mr Harsh KhajgiwaleImage Delegate ID Theme Details


Research


Organisation : Druva Data Solutions

Designation : Engineer DevOps

Amongst multiple domains spanning the radius of information and technology industry, the advent ofhealthcare has taken overwhelming pace. When it comes to the digitalization of healthcare industry,compliance and regulations (eg: HIPAA) are the principal and essential considerations since patientas an entity consists of major personal data which is sensitive. A lot of times it happens that apatient who has already consulted a doctor in one city for a specific disease, needs to consultdoctor in another city. Doctor expects older prescriptions and reports specifying the medicalhistory of a patient. A patient with planned appointment to doctor carries all the prescriptions andreports, but for the ones that need to consult doctor in case of medical emergency it becomesdifficult to produce medical documents as expected by doctor. Thus it is evident that patient’sdata needs to be stored centrally. Important factors considered in the proposal while digitalizingthe health industry in the order of their relevance are compliance, infrastructure, data volume,computational logic and centralization of patient’s data. Another dimension to this is theadoption of machine learning where model developed will learn about medical conditions of patientfrom the training datasets and would predict if the patient would be or is prone to some otherdisease and possible treatments that would cure patient. Training dataset mentioned containsconsolidated matrix of data that is aggregated from medical history of multiple patients, spanningmultiple dimensions and comprises of multiple columns such as age, geography, genetic history, listof existing diseases, frequency of consulting doctors, frequency of same illness, etc. When apatient takes appointment from a doctor, he/she provides mobile number and presently as a part ofDigital India mission all the mobile numbers are linked to Adhaar card and in turn it is linked toPAN card. Thus when a doctor provides medical prescription to patient, same data is stored in thecentralized database. Hence when patient consults some another doctor his/her medical history isvisible to doctor. Subsequently the data is fed to training dataset as a part of automated scheduledactivity. Proposed machine learning model will learn from the data that is fed dynamically as andwhen the patient consults doctor. Developing proper framework that is compliant to various nationaland international standards and regulations is of primary importance, since this domain deals withthe patient's sensitive details and clinic’s data.

Mr Pranjal SharmaImage Delegate ID Theme Details


Research


Organisation : Swami Keshvanand Institute Of

TechnologyDesignation : Student

In recent years geologists have put a lot of efforts trying to study the evolution of earth using different techniques studying rocks, gases and water at different channels like mantle, lithosphere and atmosphere. Some of the ways are Estimation of heat flux between the atmosphere and sea ice, Modelling global temperature changes, Groundwater monitoring networks etc. But algorithm involving the study of earths evolution has been a debated topic from decades. Also, there are distinct research on studying the mantle, lithosphere and atmosphere using isotopic fractionation which this paper combines and uses this common factor of isotopic fractionation in these channels to add up in the quantum genetic algorithm, which works on human genetics but this could be molded to study earths evolution. We combined this factor as the gases containing these isotopes moves from mantle to lithosphere or atmosphere through gaps or volcanic eruptions contributing to it. We will likely be using the Rb/Sr and Sm/Nd ratios to study the evolution of these channels. In QGA the chromosomes depict the characteristic of a generation here these ratios will depict the temperature characteristic. The parts of genetic algorithm consist of describing population, performing mutation, crossover over the population, calculate fitness and thus finding probability of survival and then selection. Population description will be on the basis of isotopic fractionation making an 8-bit chromosome using the isotopic ratios we will convert the actual ratio in the binary form. Then we will mutate those chromosomes i.e. the past temperature effects leading to present conditions that determine change in that ratio not in the binary form but changes will be made to ratios. Crossover is included at the stage when the isotopes moves from one channel to another mixing different ratios, like the gasses from mantel moves to atmosphere during volcanic eruption. Next step will include the calculation of fitness function if that ratio is suitable for the stabilization of mantle, lithosphere and atmosphere that instinctively tells about the change in temperature which further signifies the existence of earth on the basis of stellar metamorphosis hypothesis by Wolynski Taylor, the hypothesis explains what happens as a star cools and combines its elements into molecular compounds, mixtures, colloids, solutions and suspensions and become planets, but actually stars. According to it the earth will move to Venus’s becoming colder. The last step would be selection that depicts the future changes in temperature leading to metamorphosis.

Mr VIVEK K CHATURVEDIImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : UNIVERSITY

OF ALLAHABAD, PRAYAGRAJ-211002

Designation : PhD Student

To avoid pollution and hazardous effects of chemically synthesised nanoparticles (NPs), thebiologically synthesised NPs can be a better option. Therefore, in this study, we have biologicallysynthesised silver and gold NPs by reducing the gold (HAuCl4.3H2O) and silver slats (AgNO3) withaqueous extract of Pleurotus sajor-caju and the P. sajor-caju mediated biosynthesised NPs werevalidated by colour change and confirmed by the ultraviolet–visible spectroscopy i.e. 426 nmPS-AgNPs and 531 nm PS-AuNPs, respectively. Further, characterization done by FTIR, Transmissionelectron microscopy (TEM), Energy diffraction spectroscopy (EDS) and X-ray diffraction (XRD). FTIRanalysis showed the presence phenolic, alkenes amides and alkene groups. The TEM images of PS-AgNPsand PS-AuNPs depicted the mostly spherical shape with a size range from 16 to18 and 22 to 24 nm,respectively. The results of X-ray diffraction were compared with standard which confirmed thecrystallinity of PS-AgNPs and PS-AuNPs. For medical application of NPs, anticancer properties wereinvestigated by measuring cell viability, generation of reactive oxygen species and changes in cellmorphology was also observed, all these tests were evaluated on HCT-116 human colon cancer cells.The results showed a dose-dependent decrease in the cell viability, increase in ROS and apoptosis incancerous cells.

Dr Sk Faruque AhmedImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Aliah

UniversityDesignation : Associate

Professor & HOD

Polypropylene (PP) is one of the most widely used polymer in medical, electrical, optical, thermal and many other applications, due to its low cost, desirable mechanical properties, versatile electronic properties, easiness of processing and the absence of toxic byproducts. Surface treatment of PP with electrons, protons, and plasma irradiation has been reported to affect the structural, optical, electrical as well as the chemical properties, i.e. wettability and biocompatibility for implants [1-3]. Efforts to decrease the band gap and improve conductivity have focused on Ar rather than other plasmas since it is inert and will not chemically bond to the organic surface. The proper estimation of the optical properties of PP is necessary for further application of PP associated with irradiation using Ar plasma. The nanostructure surface morphology and optical properties of PP irradiated with an Ar plasma were studied in detail. PP formed the emboss-like nanostructure of ~ 50 nm for shorter Ar plasma treatment times, while the emboss-like structure was transited into a 3-D long nanofiber-like nanostructure for longer treatment times. The Raman analysis showed the conducting amorphous carbon increased on the surface of PP. The optical transparency and optical band gap decreased with increasing Ar ion beam treatment time. The optical band gap decreased from 3.53 to 3.40 eV with increasing Ar plasma treatment time from 0 to 50 min. The surface hardness and plane strain modulus of the PP decreased from 0.11 to 0.07 GPa and from 1.75 to 1.26 GPa, respectively, with Ar plasma irradiation time due to the surface nano-structures formed by Ar plasma.

References:

[1] Bhat, N.V.; Upadhyay, D. J. J. Appl. Polym. Sci. 2002, 86, 925. [2] Gomathi, N.; Neogi, S. Appl. Surf. Sci. 2009, 255 7590-7600 [3] Leech, P.W.; Lee, R.A. Microelectronic Eng. 2007, 84 25-30.

Mr mohibul khanImage Delegate ID Theme Details


Research



scholar

Last few decades it has been an ascending part in semiconducting chalcogenide (sulfides, selenides and tellurides) nano range thin film for their extensive range of application in different area of science and technology. CdS is very interesting remarkable for its structural, optical, electrical, magnetic and dielectric properties, it is furthermore interesting material due to its optoelectronics and photoconductive properties. CdS thin films widely used in different area of applications in practical field such as transparent window materials, photoluminescence devices, gas sensors, solar cells, laser materials, radio detectors, thermoelectric devices, photo voltaic cells etc. There are different synthesis techniques are used for the preparation of CdS thin films such as RF Sputtering, dip coating, chemical bath deposition, chemical vapor deposition, spray technique, thermal evaporation, molecular beam epitaxy and sol-gel technique. We have deposited the CdS thin film via cyclic voltammetry (CV) three electrode deposition technique which is a simple and low-cost method. We deposited CdS thin films on the Indium tin oxide (ITO) coated glass substrate via CV three electrode deposition technique. The structural properties of the thin films characterized by using X-Ray diffractometer and surface morphology analyzed by using Atomic Force Microscope. X-ray diffraction patterns of the thin films were shows that nano crystalline in nature with cubic structure at (200) as the preferential orientation. Chemical compositions of the thin films investigated by using Fourier Transform Infrared Spectroscopy. Optical analysis of the CdS thin films deposited over ITO glass was performed by using UV-Visible. The UV-Vis spectroscopy studies show that the transparency of the films decreases with increased of deposition time. The optical band gap energy decreased from 2.92 eV to 2.28 eV with the increasing of deposition of time from 15 minute to 60 minute respectively. The Urbach energy increased with the increasing of deposition time.

Dr Md Shahbaz AlamImage Delegate ID Theme Details


Research



Scholar

Diamond like carbon (DLC) has been extensively studied because of their unique properties such as high hardness, low friction coefficient, chemical inertness and resistance against corrosion and potential applications in science and technology. DLC is a metastable form of amorphous mixture of sp2 and sp3 hybridized carbon atoms, where the collective behavior of sp2 sites is responsible for the optical and electrical properties and the sp3 sites are govern the mechanical properties. The sp2 and sp3 bonding ratio in the DLC matrix can be changed by the doping of different metal and non-metal such as Sn, Au, Pt, Cu, Mo, Ti, and W etc the composition i.e., sp2 and sp3 bonding ratio in the DLC matrix. In the DLC field, silver incorporated diamond like carbon (Ag:DLC) thin films are very important because they can solve some major drawbacks of pure DLC such as, reduce residual internal stress, improved hemocompatibility properties, and enhanced the electron field emission property etc. Study of field emission from DLC materials deposited on soft substrate is interesting for many reasons to help in technological application particularly flexible electronics. In this present work, we reported the electron field emission from thin film deposited on soft substrate and silicon substrate by direct current plasma enhanced chemical vapor deposition technique. Atomic percentage of Ag in the DLC thin films was determined by using energy dispersive X-ray analysis deposited on silicon substrate. The chemical composition i.e., sp2/sp3 ratio of the Ag:DLC films calculated from the Fourier Transform Infrared Spectroscopy spectra. The surface morphology was analyzed by using scanning electron microscope, which shows the wavelength of the created wrinkle of Ag:DLC thin film decreased. Due to evolution of surface nanostructure and the change in electronic structure, the Ag:DLC film shows good electron field emission properties.

Ms SARAH PRISCILLA SAMUELImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : S.D.N.B

VAISHNAV COLLEGE FOR WOMEN, CHROMEPET,

CHENNAI-44Designation : ASSISTANT

PROFESSOR

Nano science is the study of structures and materials on the scale of nanometres. Nanostructures areextremely small and specialized structures, the technology that deals with the application of Nanoscience is called as Nanotechnology. It is the science of miniature that is able to create many newmaterials and devices with the wide range of applications in foods and technology, having an impacton several aspect of foods, from the farm to fork. The foods that use nano particles andnanotechnology techniques during cultivation, production, processing or packaging are known as Nanofoods. It is not that foods are produced by nano machines, nano particles are used in the process asnano inside as additives and nano outside as packaging. The science that deals with foods isemerging in a fast way with collaboration of nanotechnology and this has the potential to improvefood processing methods with wide nutrition and health benefits. Nanotechnology gives the producersthe power to control food looks, tastes, flavor, bacterial growth, shelf life and food safety of thedeveloped product. Nanotechnology assisted processing and packaging in food technology seems to beeffective and unimaginable and has proved its great competence in food sector.

Dr Saikat BhaumikImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Institute of

Chemical TechnologyDesignation : Assistant

Professor

In past few years, lead halide based perovskites with formula APbX3 (A: Cs, MA = CH3NH3, FA =CH(NH2)2; X = Cl, Br, I) have shown remarkable progress in the fields of solar cells, light-emittingdevices, photodetectors, lasing, due to their excellent optical and electrical properties. Recently,perovskite nanocrystals (NCs) also have received broad attention for their unique properties, likehigh PL quantum efficiency (PLQE), low defect states, large absorption cross-section, emission colortunable over entire visible range and low-threshold energy for lasing. Here I will talk aboutphoto-physical properties of perovskites, their nanoparticles synthesis, LED and solar cells devicefabrication and future aspects.

Mr Ritesh KumarImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : GGSIP

UniversityDesignation : Ph.D. Scholar

Effect of nano-cellulosic fiber on mechanical and barrier properties of Polylactic acid (PLA) green nanocomposite films Ritesh Kumar1, Sanju Kumari1, Bhuvneshwar Rai2, Gulshan Kumar1, * 1 University School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, New Delhi 110078, India. 2 Material Science Division, Shriram Institute for Industrial Research,19 University Road, Delhi 110007, India. Corresponding author Email Id: [email protected] Abstract: Most of the packaging products are made up of non-biodegradable materials resulting in environmental pollution, so the materials derived from natural resources such as polylactic acid and cellulose nanofibers have been strongly advocated as potential material for packaging materials. In this work, optically transparent green nanocomposite films were prepared by the incorporation of cellulose nanofibers into the polylactic acid (PLA) matrix at three concentrations of 1%, 3% and 5% (dry weight of CNFs in relation to PLA weight) using a cost-effective solvent casting method. The prepared green nanocomposite films of various concentrations were tested for mechanical properties and examined by a range of SEM, XRD, FT-IR, UV-Vis Spectroscopy, Contact angle, barrier properties, thermogravimetric analysis (TGA/DTG) techniques, respectively. Observation by means of scanning electron microscopy (SEM) confirmed the uniform distribution of CNFs into the PLA matrix. Overall, CNFs improved the physical properties, such as mechanical and barrier properties of the prepared nanocomposite films. Specifically, a higher loading 5% of CNFs in the PLA matrix enhanced the barrier and mechanical properties of the nanocomposite film compared to those of the pristine PLA films. Thus, the incorporation of CNFs into PLA matrix led to the production of eco-friendly nanocomposite films that may offer the possible application in food packaging. Keywords: Polylactic acid; cellulose nanofibers; transparent film; nanocomposite film References: 1. Gonçalves Carolina , Gonçalves C. Inês, Magalhães D. Fernão and Pinto M. Artur.Polymer. 2017, 9, 1–37.

Mr Manoj YadavImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : IIT Ropar

Designation : Visvesvaraya PhD Fellow (5th year)

Resistive Random Access Memory (RRAM) has been widely explored as possible substitute toconventional flash memory. However, there were still few physical phenomenon to be explained andunderstood properly before implementing RRAM as replacement of flash memory. Such class of the RRAMdevices are termed as filamentary RRAM. There is another class which is potentially applicable toneuromorphic applications, termed as non-filamentary RRAMs. Such devices shows an analog memorycharacteristics which can be utilized for the neuromorphic hardware fabrication. We present work onsuch bilayer devices having HfO2 as blocking layer and TiO2 as switching layer. For few devices, wealso embed nanoparticles to introduce strong trapping and detrapping effect which ultimately resultsin an interesting device characteristics, useful for neuromorphic computing crossbar arraysfabrication. In summary, the work revolves around fabrication and characterization of RRAM devicesfor neuromorphic computing.

Dr Shikha AwasthiImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : IISc BangaloreDesignation : Post-Doctoral

Fellow

Mutilation of various industrial devices like rechargeable-batteries, magnetic recording heads from mcorrosion and wear can be protected by carbon coatings on nickel surface. This article presents a comprehensive study of the corrosion, magnetic and tribological behaviour of electrophoretically deposited Ni with the carbonaceous reinforcements, i.e. diamond (Ni-D), carbon nanotubes (Ni-CNT) and graphene (Ni-Gr). Enhanced corrosion resistance of Ni-D coating (1920 U cm2) than that of pure Ni (552 U cm2) and permanent magnetism with higher magnetic coercivity (413.56 Oe), compared to that of Ni-CNT (132.91 Oe), Ni-Gr (124.63 Oe) and pure Ni (129.07 Oe) coatings, is linked through the interfacial anchoring via distribution of the reinforcements. Enhanced magnetic coercivity and remanence of Ni-D coating is attributed to a wider domain wall width (1.65 mm) which has enhanced magnetostatic energy per unit area near the surface (3.16 erg/cm2) compared to that of CNT (2.25 erg/cm2) and grapheme (0.94 erg/cm2). Moreover, compressive stress (_611 MPa) existing in Ni-D coating have shown to seal the micro-cavities restricting the onset of corrosion and wear. With an enhanced corrosion resistance, magnetism and frictional resistance (reduced coefficient-of-friction, scratch wear volume and high scratch hardness), Ni-D coatings can be effectually applicable for batteries, marine, automotive and aerospace industries.

Mr JAMILUR ANSARIImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : GURU GOBIND

SINGH INDRAPRASTHA UNIVERSITY, NEW DELHIDesignation : RESEARCH

SCHOLAR

Enhanced photocatalytic activity of silver nanoparticles decorated two dimensional MoS2 based template

Jamilur R. Ansari*, Neelam Singh and Anindya Datta* University School of Basic and Applied Sciences, Guru Gobind Singh Indraprastha University, Sector 16-C, Dwarka, New Delhi-110078, India.

Contact Author’s e-mail address: [email protected], [email protected]

Abstract: In this research, hybrid nano-structure consisting of silver nanoparticles (Ag NPs) decorated on two dimensional MoS2 based template were prepared by liquid exfoliation method to remove organic dyes from desecrate water. The photocatalytic activity of this hybrid system was studied by sunlight driven photocatalytic degradation of methylene blue (MB). We observed that Ag-MoS2 hybrid structure show extreme enhancement of photocatalytic activity towards MB degradation. The Schottkey junction between the metal and semiconductor leads to formation of sink for photo-excited electron, which leads to improved photocatalytic activity of the hybrid systems. Highly eradication rate of MB from organic contaminants by solar irradiation is the possible mechanism for such hybrid structures. Ag NPs of 2 nm and 7 nm decorated on MoS2 sheets was determined by TEM/HRTEM, while the chemical composition was found using X-ray Photoelectron Spectroscopy (XPS). In addition, the efficiency and degradation rate was monitored by UV-Vis analysis.

Keywords: Ag-MoS2; hybrid nanostructures; methylene blue; liquid exfoliation; photo-catalysis

References: 1. M. Kheirabadi, M. Samadi, E. Asadian, Y. Zhou, C. Dong, J. Zhang, A.Z. Moshfegh, J. Colloid Interface Sci. 537 (2019) 66–78.. 2. J.R. Ansari, N. Singh, S. Mohapatra, R. Ahmad, N.R. Saha, D. Chattopadhyay, M. Mukherjee, A. Datta, Appl. Surf. Sci. 463 (2019) 573–580.. 3. L.K. Dhandole, S.-G. Kim, Y.-S. Seo, M.A. Mahadik, H.S. Chung, S.Y. Lee, S.H. Choi, M. Cho, J. Ryu, J.S. Jang, ACS Sustain. Chem. Eng. 6 (2018) 4302–4315.

Dr swapnil rajobaImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Tuljaram

Chaturchand College, Baramati

Designation : Associate Professor (N.G.)

The energy storage capacity of the storage device can be improved by using nanotechnology. Various techniques are applied to synthesize nanomaterial for the energy storage device. In the current work economical and easy solution combustion technique is reported to synthesize cost-effective, eco-friendly and high theoretical capacity material such as NiMn2O4. Phase pure nanocrystalline NiMn2O4 is successfully synthesized at stoichiometric oxidant to fuel ratio. Its crystallinity and purity are controlled by varying calcination temperature, which is observed in the XRD pattern of the material. Effect of calcination temperature on the physical properties of material such as morphology, presence of residual carbon in the calcined material is studied by using SEM and CHNS analysis respectively. Furthermore, the presence of residual carbon is confirmed by using Raman spectroscopy. The synthesized material can be used as an anode material for lithium-ion battery and electrode material for supercapacitor as well as the hybrid capacitor. Charge storage performance of material is studied in aqueous electrolyte. Enhanced storage performance is observed due to the formation of a well crystalline material and the presence of residual carbon material.

Keywords: Nanomaterial, NiMn2O4, hybrid capacitor and lithium ion battery

Mr Alapan PaulImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Dr. B.C.Roy

College of Pharmacy & Allied Health Sciences,Durgapur.Designation : Researcher

The Future of Nanomedicin and Biotherapeutics in the Care of Nanobots Researcher Alapan Paul , Associate Prof. Kajal Ghosal e-mail address - [email protected] , [email protected]

Abstract: Since the beginning of the concept of drug delivery, researcher are trying to find the optimum system of delivering the drug to the patient’s body ensuring maximum efficiency while maintaining minimum level of adverse effect. The perfect balance between price and therapeutic affectivity is the key of making new novel drug delivery system. Use of nanobots in the field of medicine is like a new dawn of prosperity in novel drug delivery system. Detection of any particular disease accurately at any given time is also possible with these nanodevices. The true reason of popularity of nanobots lies in its ability of performing wide array of diverse operations such as sensing, actuating, information processing, treating and monitoring various diseases. Nanobots are mainly self-regulated and propelled nano-mechanical devices ranges from 1-100 nm. They are pre-programmed or can be controlled from outside. The main advantage of nanobots over other conventional or novel doses form is the complete control of bots at any given time and negligible chances of adverse effect while maximizing the therapeutic effect. Currently nanobots are in pre-clinical trials and showing promising results. The field in which nanobots are going to be used are treatment of cancer (lung, liver, Breast etc), gene therapy, surgery, nanoneedles, damage tissue repairing, anti HIV nanobots, diabetics, neurodegenerative disease, oral disease and diagnostic purpose.

References: 1) Bhat, A.S., 2014. Nanobots: the future of medicine. International Journal of Management and Engineering Sciences, 5(1), pp.44-49.

Ms Susmita RoyImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Dr. B.C.Roy

College of Pharmacy & Allied Health Sciences,Durgapur.Designation : Researcher

Carbon Nanotubes as a Revolution in Novel Drug Delivery System Researcher Susmita Roy, Associate Prof. Kajal Ghosal e-mail address – [email protected] , [email protected]

Abstract: In this generation of targeted drug delivery system carbon nanotubes shows a very promising aspect. There are many drugs available which have very narrow therapeutic window; this is especially true in case of chemotherapeutic agent used in the treatment of cancer. That’s why precise targeting of drugs towards receptors becomes a necessity. Carbon nanotubes are one of the prime candidates which can act as efficient drug delivery system for potent drugs which have narrow therapeutic window. Carbon nanotubes are special type of allotropes of carbon made up by one atom thick carbon sheet which is rolled in a cylindrical shape. Its diameter lies on the nanometer range. The 1st concept of carbon nanotubes described and observed by Radushkevich and Lukyanovich at 1952 and then single and double walled nanotubes later observed by Japanese scientist SumioLijima at 1976. The main advantage of carbon nanotubes are their low toxicity and non-immunogenicity. A carbon nanotube delivers the cargo of drug, bioactive peptides, protean and nucleic acid to the pre-programmed cellular region. The drug or other therapeutic agents are loaded on surface or centre of the tube depending upon the affinity of drug towards the nanotubes. Carbon nanotubes have great future aspect in the field of nanomedicine and nanobiotechnology due to its versatility of using different drugs and other therapeutic agent without triggering immune response while maintaining minimum toxicity. References: 1. Ouyang M, Huang JL, Cheung CL, Lieber CM. Atomically resolved single-walled carbon nanotube intramolecular junctions. Science. 2001;9(5501):pp.97–100.

Mr Sabir AlamImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : K R

mangalam university Gurgaon Haryana

Designation : PhD. Scholar in Pharmacy

Microwave irradiation (MI) process characteristically enables extremely rapid “in?core” heating of dipoles and ions, in comparison to conventional thermal (conductance) process of heat transfer. During the process of nanoparticles synthesis, MI both modulates functionality behaviors as well as dynamic of reaction in favorable direction. So, MI providing a facile, favorable and alternative approach during nanoparticles synthesis nanoparticles with enhanced catalytic performances. Although, conventionally used reducing and capping reagents of synthetic origin, are usually environmentally hazardous and toxic for living organism. But, in absence of suitable capping agent; stability, shelf life and catalytic activity of metallic nanoparticles adversely affected. However, polymeric templates which emerged as suitable choice of agent for both reducing and capping purposes; bearing additional advantages in terms of catalyst free one step green synthesis process with high degree of biosafety and efficiency. Another aspect of current works was to understand role of process variables in growth mechanism and catalytic performances of microwave processed metallic nanoparticles, as well as comparison of these parameters with conventional heating method. However, due to poor prediction ability with previously published architect OFAT (One factor at a time) design with these nanoparticles as well as random selection of process variables with their different levels, such comparison couldn't be possible. Hence, using gum Ghatti (Anogeissus latifolia) as a model bio?template and under simulated reaction conditions; architect of QbD design systems were integrated in microwave processed nanoparticles to establish mechanistic role these variables. Furthermore, in comparison to conventional heating; we reported well validated mathematical modeling of process variables on characteristic of nanoparticles as well as synthesized gold nanoparticles of desired and identical dimensions, in both thermal and microwave?based processes. Interestingly, despite of identical dimension, MI processed gold nanoparticles bearing higher efficiency (kinetic rate) against remediation of hazardous nitro dye (4?nitrophenol), into safer amino (4?aminophenol) analogues.

Mr Amar RatanImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Guru Gobind Singh Indraprastha University

Designation : Ph.D. Research Scholar

Swift heavy ion beam irradiation is an advanced method to tune or modify the properties of a wideclass of materials up to electronic level. High-performance polymer nanocomposites are a class ofmaterials that have drawn immense scientific attention due to their remarkable properties in thefield of organic electronics. In this work, MoS2 nanosheets are first synthesized via solventassisted exfoliation and then incorporated as filler in Polyvinyl alcohol matrix. The free-standingpolymer nanocomposite film was irradiated using 80 MeV Carbon swift ion beam at 1 x 1010 ions/cm2, 1x 1011 ions/cm2 and 3 x 1011 ions/cm2 to induce structural, spectroscopic and electrical changes dueto high deposition of energy. XRD and Raman reveal the annealing effect at low fluence of at 1 x1010 ions/cm2. Upon Swift heavy ion irradiation, a remarkable rise in the conductivity forapplication in organic electronics, from 2.58E-5 S/cm to 2.43E-3 S/cm at 1x1010 ions/cm2 has beenobserved. The conductivity continues to rise with increase in ion fluence and attains a value of4.92E-3 S/cm at 3x1011 ions/cm2. This is attributed to the formation of conductive tracks andhomogeneous dispersion upon SHI irradiation in accordance with Thermal spike model.

Dr Eepsita PriyadarshiniImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : School of

Environmental Science, JNUDesignation : National Postdoctoral Fellowship

Globalization along with fast pacing industrialization is contributing towards environmentalpollution. Water and soil contamination contributed by heavy metals is raising concerns due to thedeleterious effect these metal ions have on the biological system. Above a threshold concentration,heavy metals lead to numerous heath issues as reduced mental health, central nervous systemdisorder, deregulation of vital organs along with life threatening Alzheimer’s and Parkinson’sdisease. It is therefore essential to develop a rapid, feasible, cost-effective method to detectthese metal ions in aqueous solvent. Nanoparticles/nanomaterials represent an excellent substratefor this because of their miniscule size, high surface to volume ratio and superior opticalproperties. In this study, we have used nanoparticles from various biological substrates(biosurfactant, amino acids and fungal extract) for feasible detection of metal ions as mercury,lead, chromium and cerium. Noble metal nanoparticles (Gold and Silver) posses fascinating opticalproperties in the phenomenon termed as surface plasmon resonance (SPR). Any minute alteration in thesize, morphology or aggregation state of the nanoparticles would lead to alterations in the electronconfinement which gets reflected in the plasmon peak. The changes are visible via a distinct changein colour of the colloidal suspension which forms the basis of the detection system developed. Goldand silver nanoparticles were synthesized using biosurfactant and amino acids. Characterization wasperformed using UV-Visible spectroscopy, Dynamic light Scattering, Transmission Electron Microscope,FTIR, XPS, SEM and XRD. Valine capped gold nanoparticles were used for feasible detection of leadwith a minimum detection limit (MDL) of 30.5?M. A stoichiometric binding ratio of 1:2 was found onbinding of Pb2+ with valine-GNPs. Likewise, lipopeptide biosurfactant assisted silver nanoparticleswere analysed for their ability to detect mercury ions. A change in colour from brownish to whitewas observed with increasing concentration of mercury ions in the range of 20 – 100 ppm. Thesilver nanoparticles catalysed reduction of Hg2+ ions to Hg0 ions that resulted in tree shapedaggregation patterns. Various analytical instrumentation was used for characterizing the aggregationprocess. The developed assays avoid the need of additional functionalization ligands and enable realtime detection of metal ions in aqueous samples through a simple, naked eye visible detection. Theprocess is being further optimized for a kit-based and column purification approach that would helpin removal of heavy metals form contaminated water samples.

Mr RISHIBRIND KUMAR UpadhyayImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Indian

Institute of Technology (BHU), Varanasi


In this present work, we demonstrated the fabrication of Al-doped ZnO (AZO) thin-film based MetalSemiconductor-metal Photodetector. ZnO and Al-doped ZnO synthesis using the sol-gel method. Theprepared AZO and ZnO thin film are characterized by X-ray diffraction (XRD), high resolutionscanning electron microscope (HRSEM), photoluminescence and UV visible Spectroscopy. XRD resultconfirmed the formation of the Hexagonal wurtzite structure of ZnO. HRSEM image of ZnO and AZO thinfilm confirmed the uniform distribution of particles and average particle size ?30 nm and ?60 nmrespectively. An efficient photoluminescence band is observed at 447 nm and 435 nm in ZnO thin filmand AZO thin film respectively at ambient temperature when excited with 370 nm wavelength light.Finally, the ZnO and AZO thin films based fabricated metal-semiconductor-metal (MSM) Photodetectorare investigated for an electrical and optical response.

Mr Kushal DasImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Rajiv Gandhi

Institute of Petroleum Technology


Nanofluids based on metal oxide nanoparticles (NPs) are advanced nanomaterials in which oxide NPsdue to high specific surface area and dispersion stability may provide promising possibilities forvarious applications including their use for oilfield industries. However, CuO NPs (being solidcharged particles) tend to aggregate and form NP clusters which are subjected to prematurely settlewith time thus, rendering unstable and rheologically damaged nanofluid. In this work, CuO NPs invarying concentration (0.1 – 1.0 wt%) in base of polyacrylamide (PAM), were tested forhomoaggregation and rate of sedimentation (ROS). CuO nanofluid prepared in the presence of differentconcentrations was also analyzed by dispersion stability DLS, and rheological studies. The CuOnanofluids exhibited enhanced dispersion stability of more than 04 weeks with reduced size of NPaggregates. Moreover, the effect of shear deformation on rheological properties of CuO nanofluidswas marginal, mainly due to the presence of CuO NP which controlled the properties of nanofluid. Thestudy highlighted important aspects of colloidal suspensions and is a forward step towards the useof CuO based nanofluid for industrial applications including oilfield.

Mr Souvik GhoshImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Indian

Institute of ScienceDesignation : PhD scholar

Controlled manipulation of nanoscale objects in fluidic media is one of the defining goals of modern nanotechnology. In this respect, optical traps based on highly localized electromagnetic fields around plasmonic nanostructures offer a promising solution in generating strong trapping forces at low levels of optical illumination. However, conventional plasmonic trapping occurs at predefined spots on the surface of a nanopatterned substrate where trapping is limited by the diffusion of colloidal objects into a small trapping volume which renders the process inherently slow. As we discuss here, this limitation can be overcome by integrating plasmonic nanostructures with magnetically driven helical nanoswimmers and maneuvering these mobile nanotweezers under optical illumination(1). In an alternate strategy, a similar functionality has been obtained in a unique nanooptical device, where sub-micron colloids could be manipulated using optical forces alone(2).

We have achieved new functionalities such as selective trapping and positioning, single as well as collective transport, independent and parallel control, size-selective sorting of various nanomaterials including fluorescent nanodiamonds, magnetic nanoparticles and even single sub-micron sized bacterium at a low laser power that were not demonstrated before. This demonstrated technology may enable isolation, manipulation and chip-level assembly of nanomaterials and allow non-invasive manipulation of fragile bio-specimens, such as bacteria, virus and various macromolecules.

Work published in: Science Robotics (Impact factor: 19.8) and Nature Communications (Impact factor: 13.8)

1. S. Ghosh, A. Ghosh, Mobile nanotweezers for active colloidal manipulation. Sci. Robot. 3, eaaq0076 (2018). 2. S. Ghosh, A. Ghosh, All optical dynamic nanomanipulation with active colloidal tweezers. Nat. Commun. 10, 4191 (2019).

Ms Muskan -Image Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : NIT-BHOPAL


Alumina coated steel shows superior anti-corrosive nature as well as erosion resistance and wear resistance. The present work investigates the possibility of alumina coating on a steel substrate via a solution combustion synthesis (SCS). Aluminium nitrate solution is used as a precursor and urea is used fuel to obtain the coating. The adherence of the coating studied using different interface layers and their structural and morphological characteristics were investigated using XRD, SEM and EDX techniques. The SEM studies showed coatings with a thickness of 100 to 120 µm consisting of micropores within the structure. Subsequent annealing found to have reduced the percent of porosity. The XRD analysis of the coating confirmed the presence of alpha-Al2O3. The hardness of the coatings was high i.e 1245 HV 0.05 and also showed excellent wear resistance. The wear rate of conventional steel is about 20 µm per km while the coated material showed about 5 µm per km. Further, it is also found that the corrosion resistance of the steel is significantly improved by the sol-gel alumina coating. The present work demonstrated that Sol-Gel alumina coated steel could be a promising candidate for hydropower plant applications.

Keywords: Corrosion, Wear, Alumina Coating, Sol-Gel, Hydropower plant materials

Dr ASHWANI SINGHImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : JNUDesignation : PDF

In the present study, we demonstrate the synthesis of the nanocomposite of reduced graphene oxide (rGO) with CdSe and CdSe/V2O5 core/shell quantum dots by a two-step simple and facile synthesis approach consisting of a lyothermal and solvothermal methods. Various characterization techniques have been applied including Transmission Electron Microscopy (TEM), X-Ray Diffractometer (XRD), Raman spectroscopy to confirm the formation of CdSe-rGO and CdSe/V2O5-rGO nanocomposites. The average sizes of CdSe and CdSe/V2O5 QDs have found to be ~ 3 and 5.5 nm, respectively with a good dispersion over the surface of rGO. A crystal phase change has occurred during the formation of V2O5 shell over the surface of CdSe QDs and confirmed through XRD. Raman spectroscopy has shown some useful insight into the surface state of CdSe and consequent changes in the surface with V2O5 shell growth. Further, these nanocomposites have been analyzed for their biocompatibility in different cell lines. MTT and cell growth assays have been studied in A549 and Hela cells with various concentrations of as-synthesized materials. Our results show that the toxicity of CdSe-rGO nanocomposite to be substantially reduced by the growth of V2O5 shell. The in vivo studies in Drosophila show decrease in the reactive oxygen species (ROS) and apoptosis levels for CdSe/V2O5-rGO composite as compared to CdSe-rGO nanocomposite, which paves the promising pathway for it to be used as an efficient biocompatible material.

Mr AKSHAYA KUMAR AImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Mangalore

UniversityDesignation : Inspire

Fellow(JRF)

The detection and controlling of soil physicochemical conditions play a significant role in theagricultural applications. The arrangements of interdigitated electrodes (IDEs) and nanostructuredactive layers have will increases the electrochemical performance of the sensors. Herein, we reportthe design and fabrication of screen printed IDEs based pH sensor by using hydrothermal growth ofZnO nanorods (NRs). A three-step deposition of ZnO seed layer followed by a hydrothermal treatmentlead to the heavily ordered ZnO NRs patterns on the screen-printed IDEs. The structural, chemicalcompositional and electrical properties of the NRs were investigated and examined by using fieldemission scanning electron microscopy (FeSEM), atomic force microscopy (AFM), energy dispersivespectroscopy (EDS), X-ray diffraction (XRD) technique and Keithley 4200 semiconductorcharacterization system respectively. The sensor capacitance and pH were found to be inverselyproportional at a working frequency of 1 kHz. The sensor displayed sensitivity of 1.06 nF/pH in therange of pH 4 - 10. The ZnO NRs based IDEs pH sensor present, it as with simple fabrication process,low-cost, and convenient device for measurement of pH in soil

Prof Neeraj MishraImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Amity

University of Madhya PradeshDesignation : Professor

UC is supposed to disorder due to the mutations in the genes. In which some way permits aggressive luminal bacteria to start the mucosal inflammation. The use of probiotics can change the luminal bacteria and gives anti-inflammatory action. The second concern is that UC is a mucosal disease; therapy which works o mucosal level might be beneficial. These findings initiate the researcher to test probiotics in a number of clinical trials and find out their effect on UC. he present study is using the targeted approach and anti-inflammatory action of the probiotic biomass to lessen the side effects of therapeutic agents of ulcerative colitis. The aim of the present study is to prepare mesalamine loaded eudragit S-100 with probiotic microparticles by spray-drying method. The in-vitro release of the optimized formulation was 90.55±2.42 in 24 hr, which display controlled drug release of mesalamine at a colonic region. Mesalamine loaded eudragit S-100 with probiotic microparticles (F12) presented an average particle size of 4.91µm. The statistical analysis was done by one way ANOVA and then a comparison test of Bonferroni was done and P values

Ms Monika KatariaImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Guru

Jambheshwar University of Science & Technology, HisarDesignation : Ph.D Scholar

Emergence of multidrug resistance in bacteria poses a serious threat on development of novel drugs for treating various bacterial diseases or infections. With the advent of nanotechnology, the field of biomedicine has been revolutionized due to the development of sustained release as well as targeted drug delivery approach. In the present study, we have developed antimicrobial nano-gel by incorporating the microbially synthesized metal nanoparticles with natural plant gums for topical application in wound healing. The silver nanoparticles were synthesized by bio-reduction of silver nitrate using culture supernatant of bacteria Eneterobacter cloacae as the reductant and incorporated into with plant gum-gelatin based nano-hydrogel. The biosynthesized silver nanoparticles as well as the derived nanogel were characterized using Particle size analyser, FTIR spectroscopy and TEM. The silver nanoparticles were agglomerated and encapsulated in polymer shell of size ranging between 80-140 nm. The evaluation bactericidal potential of the nanogel against various multidrug resistant bacteria showed excellent antimicrobial activity. The biocompatibility evaluation was done using MTT assay. The antimicrobial evaluation and biocompatibility results show that the nanogel can be a potential candidate for developing wound-healing dressings. References Arab, W. T., Niyas, A. M., Seferji, K., Susapto, H. H., Alexander, I., Cima, I., & Hauser, C. A. (2018). Evaluation of peptide nanogels for accelerated wound healing in normal micropigs. Front Nanosci Nanotech, 4(4); 1-9.

Dr Karunesh TiwariImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Babu

Banarasi Das University, Faizabad Road, Lucknow, UP-

226028Designation : Assistant

Professor

This article reports the humidity-sensing application of nanostructured pure WO3 and Cu2+-doped WO3nanomaterials. Pellets of this material were prepared and used as a sensing element after successivethermal annealing for 3 hours at different temperatures of 400°C to 700°C. After each annealingstep, these pellets was placed in a conductivity holder and exposed to humidity in a humiditycontrol chamber. It has been observed that as relative humidity increases, there is a decrease inthe resistance of the pellet. Sensing elements of pure WO3 and 2 weight % Cu doped WO3 annealed at400°C shows maximum sensitivity of 2.25 M?/%RH and 3.72 M?/%RH in the 10-50 % relative humidityrange and sensitivity of 1.30 M?/%RH and 0.55 M?/%RH in the 50 to 90 % relative humidity range. XRDpattern shows peaks of hexagonal tungstite. As calculated from Scherer’s formula the crystallinesize for this sensing elements pure WO3 and for 2 weight % Cu doped WO3 by sol-gel method is 83nmand 106 nm. The humidity-sensitive electrical properties of the sensing elements have been studiedusing d.c. measurements. The addition of Cu dramatically improved the relative humidity response ofsensing elements.

Ms Geetanjali SehgalImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : CSIR- NPLDesignation : Technical

Officer

TOF-SIMS high resolution depth profiling with 2D and 3D imaging for device material applications

Geetanjali Sehgal, B.R.Chakraborty and M.K.Dalai CSIR-National Physical laboratory, Dr.K.S.Krishnan Road, New Delhi-110012 Email: [email protected]

Abstract: Time-of -flight Secondary Ion Mass Spectrometry (TOF-SIMS) provide a well established tool for surface and in-depth analysis of multilayer structures and their interfaces to study the quality of the various device materials. In this paper, we have showed the applications of this technique to study the organic as well as inorganic electronic structures. We have demonstrated the use of TOF-SIMS to examine the GaN/AlN [1] multilayer over sapphire substrate (Al2O3). GaN/AlN based materials are widely used in high power and high frequency applications. The TOF-SIMS technique has been employed to study the multilayer hetrostructure of the material by obtaining the depth profile of the given sample. TOF-SIMS has also been used as an ion imaging technique to see the 2D and 3D imaging of the depth profiled data where we have observed the elemental distribution of Al, Ga, N layers on the analyzed area. AlN has shown a good lattice matching with the GaN and therefore used as alternate layers to form a supper lattice structure.[2] Also, we have studied the depth profiling with three dimensional imaging of an organic multilayer material. Recently, the depth profiling analysis of organic films has received much interest due to major developments in the areas of organic electronics, bio-engineering & medical devices. To standardize depth profiling of organic materials, an inter laboratory study using organic multilayer reference materials was carried out under the VAMAS (Versailles Project on Advanced Materials and Standards) project using cluster ion sources, like C60 or Ar2000 ions for sputtering. In this work the same reference material of Irganox3114 as buried layers of 3nm width at four different depths inside an Irganox1010 matrix was undertaken in dual beam TOFSIMS equipment with Cs+ and O2+ as sputter ion beams. The study shows that though the conventional ions like Cs+ or O2+ do not give large molecule based information like in the case of bombardment of cluster ions, but if there are unique elements or isotopes in the analyte (in this case, nitrogen) then so far as the depth resolution and its related parameters are concerned, the data shown by these mono or di-atomic ions are comparable or some times better than the data shown by cluster ion bombardment for depth profiling [3]

Ms Ruchita ShandilyaImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : ICMR-National

Institute for Research in Environmental HealthDesignation : Junior

Research Fellow

Real-time detection and monitoring of cell-free circulating miRNAs using dual-labelled aminopyrene-tethered carbon nano-composites Ruchita Shandilya1*, Irina Yu. Goryacheva2, Pradyumna Kumar Mishra1 1Department of Molecular Biology, ICMR-National Institute for Research in Environmental Health, Kamla Nehru Hospital Building (GMC Campus) Bhopal - 462 001 (MP), India; 2Department of General and Inorganic Chemistry, Chemistry Institute, Saratov State University, Astrakhanskaya 83, 410012 Saratov, Russia *[email protected] Abstract: Circulating cell-free microRNAs (ccf-miRs) have emerged as promising biomarkers for early disease prognosis and diagnosis in recent times due to unique biological and physico-chemical properties that entails small size, hairpin loop structure, low complexity, high stability and better half-life. Although use of minimal invasive liquid biopsy-based methods for isolation and subsequent detection by nucleic acid amplification techniques have positioned ccf-miRs as attractive clinical markers, however, polyadenylation at the 3' end of ccf-miRs as an obligatory step prior to amplification is not only a time consuming process but requires precise scientific skills and expertise. Of late, technological application of several miniaturized nano-frameworks that offer rapid detection of ccf-miRs have come to the fore that includes carbon based nanomaterials such as graphene quantum dots, graphene oxide, and carbon nanoparticles, due to their non-toxicity, inexpensive fabrication, and better stability in aqueous media. Fluorescent carbon nanostructures (carbon quantum dots) have emerged as a research hotspot in the recent past due to its bright and tunable light emission. The high ?-electron density of sp2 carbon-based systems offers ?- ? stacking orientation for the effective capture of short nucleotides. In the present work, dual labeled composite system comprising of aminopyrene-attached carbon nanostructures and 4?,6-diamidino-2-phenylindole (DAPI)-labelled antimiR-16-5p was developed for the efficient capture of miR-16-5p, a significantly deregulated miRNA observed in various pathologies, based on pyrene-nucleobase conjugation followed by detection. The target ccf-miR sandwiched between aminopyrene-attached carbon nanostructures and DAPI-labeled antimiR sequence was detected using flow cytometry. The assay reported a cluster in the aminopyrene-tethered carbon nano-composites and DAPI-antimiR double positive quadrant confirming the ?- ? stacking of miR-16-5p in the sandwiched structure with respect to the clusters present in the aminopyrene-tethered carbon nano-composites and DAPI-antimiR positive quadrants respectively. The present work portrays a simplified procedure without the need of any complex functionalization or surface modification steps for rapid detection of target ccf-miRs. Our novel flow cytometry based assay offers a pragmatic approach for real time analysis of ccf-miRs that are aberrantly expressed in spectrum of communicable and non-communicable human diseases.

Ms Bharti sharmaImage Delegate ID Theme Details


Research


Jambheshwar University Science and TechnologyDesignation : Research

scholar

Abstract: In recent years, there has been a significant increase in studies related to detection of hazardous substances. The reason behind such investigations is continued growth of anthropogenically-derived environment pollutants. However, different sensors have been reported for up to date for the detection of N2H4 but most of them involve complex procedures and sophisticated instrumentation. In order to overcome these problems, SnO2/nanocomplex based sensor is used due to its simplicity and rapidity. Tin oxide nanoparticles (SnNPs) were synthesized using the hydrothermal technique and further functionalized with GO. The G-SnO2 nanocomposite was used for the fabrication of a modified electrode for the detection of hydrazine. The GC/G-SnO2-modified electrode showed a good electrocatalytic activity, as the graphene sheets prevented the agglomeration of SnO2 nanoparticles, which in turn increased the sensitivity and selectivity. The electrochemical sensing of N2H4 was done using chronoamperometry. In amperometry, the oxidation peak current increased with an increase in the concentration of N2H4 from 10 nm to 10 mm with a regression coefficient of 0.987. The sensor also showed a linear response for the oxidation of N2H4 in the range of 0.01-0.10 mM with high sensitivity of 6.36 µA/µM, and very low limit of detection 0.092 mM. In addition, the sensor exhibited good reproducibility, stability, and selectivity toward the analytes in real sample analysis. Keyword: Hydrazine, Tin oxide/ Grapheneoxide, fabricated sensor. References: 1. K. Saha, S.S. Agasti, C. Kim, X. Li, V.M. Rotello, Gold nanoparticles in chemical and biological sensing, Chem. Rev. 112 (2012) 2739–2779.

Dr Vikas KumarImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Sam

Higginbotham University of Agriculture, Technology &

SciencesDesignation : Assistant

Professor

Oral mucositis is the common complication of radiotherapy and chemotherapy of neck and head region.Chemotherapy induced oral mucositis occurs in patients (40-70%) and can limit the anticancer effectsof chemotherapy. Neutrophils are primary cells,which are modulated by immune system and theirmigration to site of infection can lead to inflammation and neurophenia in patients. As on date, nospecific therapy is currently available for protection against mucositis. The aim of the currentstudy, we scrutinize the therapeutic effect of nano-gel containing lemon oil(NG-LO) in5-fluoro-uracil (5-FU)-induced oral mucositisrodent models. Oil in water emulsion system was usedfor the preparation of nano-gel of lemon oil (NG-LO). Intraperitoneal injection of 5-FU(80 mg/kg)was used for the induction of hamsters on day 0, 6 and 9. The rodent pouches were then scratched byneedle on first, second and seventh day. Mucositis score, body weight, biochemical parameters andpro-inflammatory cytokines were estimated. NF-kB, TGF-?, Bax and Bcl-2 were also estimated. NG-LOsignificantly (Pbody weight (54%). NG-LO treatment improved the blood vessels and differentiated epidermis. NG-LOthwarts arrested the transmigration of neutrophils in the area of infection and stabilized them.5-FU-induced excessive neutrophils transmigration to infection area and also stabilizes thecirculating neutrophils. NG-LO treatment inhibited the inflammatory response such as TNF-? (65%),IL-6 (45%), IL-1? (48%) and NF-Kb (70%) in serum and tongue. It’s also inhibited the TGF-? (39%),respectively. Nanogel of Lemon oil shows the significant improvement in 5-FU induced oral mucositisby altering the biomarkers associated with inflammation.

Ms Shikha JainImage Delegate ID Theme Details


Research


Jambheshwar University Science & Technology, HISAR


Resistant microscopic organisms are an undeniably genuine risk for the wellbeing of world. So,multifunctional hybrid Nanocomposites of Zn-QDs with Ag-MOF were synthesized to study itsantibacterial efficacy. These nanocomposites were characterized by field emission scanning electronmicroscopy (FESEM) and powder X-ray diffraction (PXRD). Antibacterial activity of Zn-QDs@Ag-MOF havebeen evaluated against representative bacterial strains including Gram positive (B. subtilis) andGram-negative (E. coli), using CLSI recommended qualitative disk diffusion approach. The synergisticnanocomposite of graphene quantum dot and tuneable silver-MOF fostered an enhanced antibacterialactivity compared to either of its individual components. We determined that charge transportbetween components, Zn-QDs and Ag-MOF is key to the electrostatic interactions of the compositeswith the bacterial cell membranes. The functionalized nanocomposite allows the release of silver inthe extracellular environment. The released silver ions further interact with high affinity tothiol-ligands of the biological entities. The reaction result in the formation of metallic silver(AgO) and silver sulfides (Ag2S), suggested as critically important for the composites to inhibitbacterial growth. An enhanced bactericidal activity of nanocomposite could also be linked tomorphological features like increased surface area and specific surface chemistry. This studyintroduces that Zn-QDs@AgMOF nano-hybrids have significant bactericidal effect.

Mr Ajith M PImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Jawaharlal

Nehru UniversityDesignation : Ph.D. Scholar

Industrialization and other anthropogenic activities have resulted in the discharge of waste andwastewater containing heavy metals. Heavy metals not only bring serious environmental problems,threatening human health and ecosystem but also are becoming a scare resource, which have wideapplications. Fabrication of novel technologies using emerging fields like nanotechnology can helptackle this issue. In this context, the current study attempts to elucidate the efficiency ofbiogenic low cost Carbon Dots (CD) for selective removal of heavy metals form industrial effluentsusing column chromatography method. CD of an average size of 2 nm was synthesised using leafextracts of Ficus benghalensis. Characterization was performed by various analytical techniquesUV–Visible Spectrophotometry, Fluorescence spectrophotometer, Zeta potential, Dynamic LightScattering (DLS), Transmission Electron Microscopy (TEM), X- Ray Diffraction (XRD) and Atomic ForceMicroscopy (AFM). The selective metal (Fe, Hg and Sb) absorption ability of CD was found evidentfrom red shift of CD absorption peak to higher wavelength along with fluorescence quenching andincrease in hydrodynamic diameter of particles after metal treatment. The CDs were negativelycharged which favours binding with the positively charged metal ions, additionally, the functionalgroups on CD surface assist in selective binding. We further performed a detailed exploration of theadsorption efficiency of CD with the above mentioned heavy metal ion as a function of incubationtime and metal concentration. Moreover, column chromatography was performed using silica-CD as thesubstrate and packing column material. Industrial effluents were allowed to percolate through thecolumn and purified fractions collected which were further analysed by ASS and ICP-MS analysis.Furthermore, adsorption isotherms, kinetics and thermodynamics were studied to understand themechanism of absorption of metal ions by synthesized CD. In addition, we evaluated the effects ofbackground electrolytes on the adsorption efficiency.

Mr dhananjay ....Image Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : university of

mysuruDesignation : research

scholar

A critical need in the field of nanotechnology is the development of reliable and eco-friendly processes for synthesis of metal oxide nanoparticles. Fe2O3 -NPs with an average size of 40 ± 4 nm and cubic shapes were synthesized by bio-reduction of ferric chloride solution with a green method using Crotalaria aqueous extract contain sulphated polysaccharides as the reducing agent and efficient stabilizer. The hydroxyl, sulphate and aldehyde group present in the BS extract are apparently involved in the bio-reduction and stabilization of Fe2O3 -NPs. The involvement of these groups in biosynthesis is revealed by FTIR analysis. The characteristics of the obtained Fe2O3 -NPs were studied using FTIR, XRD, UV-visible, SEM and HR-TEM, techniques. Biosynthesis of Fe2O3 -NPs using green resources is a simple, environmentally friendly, pollutant-free and low-cost approach with dye degradation applications. The functional bioactivity of Fe2O3-NPs antimicrobial is comparably higher than particles which were synthesized by chemical method.

Ms Madhupriya SamantaImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Jadavpur

UniversityDesignation : JRF

In this communication, Reduced Graphene Oxide (RGO) wrapped Copper Phthalocyanine (CuPc) tube has been successfully synthesized by simple chemical route and its capability of textile dye like Rhodamine B (RB) removal is also investigated under the presence of two types of ultrasonic irradiation. The as prepared samples are well characterized by sophisticated instruments. Recently, different types of advanced oxidation processes are gaining major interest; sonocatalytic degradation is one of them. In our case, 2 types of ultrasonic irradiation is applied to the samples. For bath sonicator, RGO wrapped CuPc tube can efficiently degrade RB upto ~78% within 100 min whereas only ~54% efficiency is achieved by pure CuPc tube whereas for probe sonicator, 92.2% and 70% RB degradation is achieved by RGO-CuPc and CuPc tube respectively. By conventional photocatalysis, 83.8% efficiency is achieved in 3.5 h by RGO-CuPc composite as per our previous report [(Mukherjee et al., 2017)]. The improved catalytic performance has a good agreement with wettability property. From the contact angle measurement, it is observed that wettability of CuPc is enhanced due to the wrapping with RGO sheet. Surface of CuPc nanotube is superhydrophobic in nature and shows water contact angle of 140? with significant stability upto 500s [Fig. 1(a)] whereas after RGO modifications, sample shows contact angle of 90? initially and rapid fall of water droplet is observed within 140 s [Fig. 1(b)]. Thus, hydrophilic nature is incorporated in CuPc tube by wrapping RGO which may play an important role in sonocatalytic dye degradation enhancing charge transfer mechanism.

Dr ROBERT XAVIER ANTONYImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : NATIONAL

COLLEGE (AUTONOMOUS)Designation : ASSISTANT

PROFESSOR

V/?-CdOV nanomaterials were synthesized through simple soft chemical method. Dextrose was used asthe reducing agent and starch was used as the capping agent. The X-ray diffraction reveals that thecompound possesses a cubic crystalline structure at nanoscale. The FESEM image shows that theresulting material is composed of nanoparticles and its size decreases with increase of V dopingrelative with the particle size calculated from XRD. The photoluminescence shows the emission ofviolet and blue colour peaks and the peak at 468 nm. The electrochemical performance of the V/?-CdOVstacked nanomaterials was examined by cyclic voltammetry and galvanostatic charge-dischargetechniques. Both studies indicate that V/?-CdOV is a suitable negative electrode material forsupercapacitor and delivers a maximum specific capacitance of 426 F g-1 at a specific current of 2 Ag-1. The asymmetric supercapacitor device yielded a specific cell capacitance of 95 F g-1 at aspecific current of 1 A g-1. The device delivers a high specific energy and specific power of 41.45W h kg-1 and 880.8 W kg-1, respectively.

Ms DEEPA SACHANImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : IIT

GUWAHATIDesignation : RESEARCH

SCHOLAR

Now a day’s environmental pollution become a global concern due to a steady deterioration in waterquality and their hazardous impact on human health. These pollutants contain traces of heavy metalsdischarged from various industrial wastewater. Therefore, their removal is essential. In the presenttime, the potential application of silica-based nanoparticles (SNPs) has gained the attention fortheir capability of efficient removal of heavy metals from industrial wastewater. Herein we reportthe green synthesis of Silica nanoparticles (SNPs) via a simple chemical method from a new plantsource containing silica. Its application as a potential nano-adsorbent for the adsorptive removalof heavy metal ions viz. Pb2+ and Cu2+ were performed in synthetic wastewater. The influence of theexperimental parameters like adsorbent dose, pH, contact time, temperature, and initial metal ionsconcentration, was also analyzed. Various isotherms, kinetics, and thermodynamics models were usedto explain the adsorption mechanism. The maximum adsorption capacity (qmax) of SNPs was achieved303.03 mg/g and 243.90 mg/g for Pb2+ and Cu2+ ions, which fitted well with Freundlich isotherm modeland pseudo second-order kinetics.

Dr SENTHILKUMAR VImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : CSIR Fourth

Paradigm InstituteDesignation : PRINCIPAL

SCIENTIST

Unlike Graphene, the Penta-Graphene behaves differently when subject to different mechanical loadings. The Penta-Graphene structure consists of five carbon atoms in different planes. Synthesis of Penta-Graphene is challenging work for researchers. Using in-house code, the Penta-Graphene Nanotube Structure[2] Generator Software has been developed for the first time. In an open-source platform, there exists no such software to generate the Penta-Graphene structure[2,3]. The Penta-Graphene Sheet and Penta-Graphene Nanotube are shown in Figure 1.0 and Figure 2.0, respectively.

References: 1. Zhang, S.; Zhou, J.; Wang, Q.;Chen, X.;Kawazoe, Y.;Jena, P. Proc. Natl. Acad. Sci.2015, 112, 2372 – 2377. 2. Chen, M.; Zhan, H.; Zhu, Y.; Wu, H.;Gu, YJ. Phys. Chem. C.2017, 121, 9642 – 9647. 3. Quijano-Briones, J.J.; Fernandez-Escamilla, H.N.; Tlahuice-Flores, AComput. Theor. Chem.2017, 1108, 70 – 75.

Ms Sweta RaniImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : IIT Bombay-Monash Research AcademyDesignation : Ph. D. scholar

Photonic crystal is a nanostructure consisting of periodically arranged dielectric materials in one,two, or three dimensions. These periodic nanostructures interact with light to produce a bandgapi.e. it prohibits the propagation of a certain range of wavelengths, while allows the otherwavelengths to propagate. Hence these structures can be used to modulate the flow of light. Severalmethods, such as self-assembly, etching, multiple-beam interference etc have been used for thefabrication of photonic crystals. Laser lithography based on two-photon polymerization is apromising technique for fabricating three-dimensional photonic crystals as it provides very highspatial resolution. This technique uses an infrared or near-infrared laser for lithography. Thecommonly used polymers for fabrication have negligible absorption in this part of theelectromagnetic spectrum. Hence the laser can penetrate deep inside the polymer and inducepolymerization in the focal volume, without contaminating the regions outside it. Hence, thisfabrication technique is considered advantageous over other conventional techniques and has beenused here. A variety of photosensitive mono-material, as well as composite materials, have been usedfor fabrication of two-dimensional (2D) and three-dimensional (3D) photonic crystals. Here, wepropose to fabricate photonic crystal by photo-patterning in a polymer, which is sensitive to anexternal stimulus such as humidity, temperature, pH etc and can be tuned over a range of wavelengthsin response to the external stimulus. We have demonstrated the fabrication of hydrogel-basedone-dimensional (1D) and 2D photonic crystal. Hydrogels are hydrophilic, three-dimensional polymericnetwork which can absorb large amounts of water. The fabricated photonic crystal incorporates theproperties of the hydrogel. Hence, it is sensitive to humidity and tends to undergo swelling uponabsorption of water. The swelling of the hydrogel changes the periodicity/dimension of the photoniccrystal and therefore, the response (bandgap) of the structure also changes. Depending on the amountof swelling in the structure, the changes in dimensions and the response of the photonic crystal canbe monitored. The capability to alter the bandgap of the fabricated structure in response to anexternal stimulus, holds a potential application for the fabrication of devices such as sensors,having a tunable bandgap and improved sensitivity. Further, we also intend to incorporate variousfunctionalities such as metallic nanoparticles, magnetic nanoparticles, etc into the polymer forexploring other applications.

Ms Shrabani GhoshImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Jadavpur

UniveristyDesignation : CSIR Senior

Research Fellow

Global energy crisis and environmental pollution are major problems nowadays. Hydrogen can beconsidered as an important alternative to replace the fossil fuels easily. Water splitting is themost efficient to produce. Platinum and platinum group of metals are ideal one for drivingsignificant current density near about thermodynamic potential but they actually suffer from expenseand corrosion in extreme electrolyte. Thus, attention has been shifted to low cost transitionmetals.In this work, NiSe2 is synthesized hydrothermally using DI as solvent at differenttemperatures like 8h 16h and 24 h. After formation, the obtained powders are characterized by XRD,XPS which confirms about the cubic NiSe2 phase for all samples. To determine the structure of thepowders, field emission scanning electron microscopy (FESEM) is performed. Figure 1(a) representsthe image of NiSe2 24h which sustains coral like structure with 10 to 80 nm diameter. After that,electrochemical HER experiment is performed for NiSe2 8h, NiSe2 16h, NiSe2 24h. Linear sweepvoltammetry (LSV) curve is represented in figure 1(b). NiSe2 8h, NiSe2 16h, NiSe2 24h require onsetpotential of 39 mV, 132 mV and 90 mV (vs. RHE) respectively. Low onset potential implies superiorHER performance. Thus in terms of onset potential NiSe2 24h is the most efficient one for HERelectrode. NiSe2 24h requires overpotential of 278 mV to achieve current density of 100 mA/cm2whereas NiSe2 8h, NiSe2 16h require overpotential of 307 mV and 372 mV to achieve the same currentdensity. Thus in terms of HER performance it can be arranged as NiSe2 24h> NiSe2 8h> NiSe2 16h.

Dr YATIN BHAMAREImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : -

Designation : PhD Scholars

Carbon based materials are considered as a rewarding contestant for optical devices due to its novel properties. Graphite is a most stable allotrope of carbon with a layered and planar structure. Graphene is the two-dimensional lattice of carbon atoms in a honeycomb arrangement, and is attracting significant attention from the scientific community. There was a rapid growth of graphene-based two-dimensional counterparts, the most famous among which is reduced graphene oxide (rGO). In this study, graphite is laser-ablated and different analytical methods such as XRD and Raman spectroscopy are used to evaluate the crystalline nature. Reduced graphene oxide is prepared by using modified Hummers method and reduced it by thermal reduction method. It is decorated with Au, Pd and Pt nanoparticles by chemical synthesis. In XRD, it indicates the decreased intensity after laser ablation but no change in peak positions resulted as graphite is very strong and hard material. UV-Vis spectra confirmed the peaks of both graphite (non-ablated and laser-ablated) and rGO at 274 nm and 267 nm, respectively. It also confirms the synthesis of rGO with Au, Pd and Pt composites successfully. Scanning electron microscopy (SEM) used to evaluate structural characteristics shows the overlapping layered structure after ablation. It also reveals the layered structure of rGO with successful composition of Au, Pd and Pt nanoparticles. Photocatalysis activity of rGO with Au, Pd and Pt performed using UV-Vis spectroscopy. rGO-Au shows faster degradation of methylene blue using both xenon white lamp and blue LED. To study the ultrafast carrier dynamics, femtosecond transient absorption spectroscopy was used. Graphite, laser-ablated graphite and rGO shows carrier relaxation between 260 and 309 fs even after laser ablation damage, which is useful for future application of optical switching under high laser repetition. rGO with Au, Pd and Pt shows similar dynamics with long lived component. Surface plasmon resonance absorption and inter-band excitation of Au nanoparticle shows rGO-Au is useful composition for photocatalysis activity.

Mr Samir ThakurImage Delegate ID Theme Details


Research

Category : Nano EngineeringOrganisation : Gauhati

UniversityDesignation : Reasearch

Scholar

Over the last 30 years, platinum-based drugs, particularly cisplatin, nedaplatin and oxaliplatintook over treating a variety of solid tumors for example ovary, lung, testis, urinary bladder andneck cancers [1]. Almost all of platinum drug possess equivalent structure, so, their particularfunction of action is identical. However, there is a drawback which is, these drugs are cytotoxicand fails to distinguish cancer cells from normal cells. Therefore, they affect both cancerous andnormal cells. Recently, enhanced drug delivery methods were investigated which has a great potentialfor improving cancer therapy [2]. Among all these methods, drug carrier systems particularlynanoparticles is often developed using certain interactions in between the cell surface and the nanocarriers associated with the drug molecules. This way, the drugs effectively transported to thecancer cells. However, at present, the development of selectively target oriented drug deliverynano-carriers still face challenges. Thus, it is important to build unique and effectivetumor-targeted drug delivery systems. Carbon nanotubes (CNTs) have revealed great potential inbiomedical, environmental applications in addition to being nanoscale vehicles for the targeted drugdelivery [3] [4]. Therefore, in this research we used functionalized carbon nanotube as a nanocarrier for the delivery of cisplatin drug molecule. Carbon nanotube is doped with magnesium atom toincrease the interaction energy of cisplatin drug molecule. The adsorption energy of cisplatin drugon undoped and doped nanotube is found to be -0.26? eV at 7.5 Å intermolecular distance and -2.36eV at 7.4 Å intermolecular distance from the centre of mass of the nanotubes respectively.Therefore, it revels that the drug molecule is strongly interact with Mg-doped nanotube thancompared to undoped nanotube. Study of reduced density gradient demonstrate that both strong andweak hydrogen bonds are found along with the Van der Waal interactions, are responsible for theinteraction of cisplatin and doped nanotube. All of our findings clearly suggest that cisplatin-Mgdoped nanotube system can be utilized as an innovative new drug delivery system which saves the drugfrom degradation.

Mr MOULI SAI KRISHNA KUMAR NYSHADAM

Image Delegate ID Theme Details


Research

Category : Mechatronics Engineering

Organisation : BVRIT Hyderabad College of Engineering for WomenDesignation : Assitant

PRofessor

Without vision it can be challenging for a blind or visually impaired to write exams. According tothe study by Sahasrabudhe et al, it gets increasingly difficult for parents to find writers duringexam time, for their children who are disabled or visually impaired. This made point of developing adevice that would assist blind or visually impaired people to write their exams without scribes.This work presents designing a working system that will help blind or visually impaired to presenttheir exams without the help of scribe. The machine which we have developed is an Electro-MechanicalScribe which is mobile/android application based and is easily accessible. The major advantage isthat the system can write the spoken contents on paper using pen. Getting text input from androidapplication, plotter will start typing accordingly on paper. This machine takes input from androidapplication and sends it to the controller wirelessly. According to input given to the plotter, itwill write letters, characters and symbols. The speech to text android based academic testingsoftware would provide an interaction for blind students to enhance their educational experience byproviding them with a tool to succeed at their school and college levels.

Mr ARVIK SAINImage Delegate ID Theme Details


Research


Organisation : JIS COLLEGE OF ENGINEERING


The solution is original and provides a creative to an experiment, resolves a problem. There is aconveyor belt connected to the system which starts moving clockwise or anticlockwise based onswitches. The speed of moving is moderate. There are IR transmitter and receiver and laser modulewhich are connected in two opposite sides of the platform at which the conveyor is connected. Thebags or the cargoes are kept in the belt and the belt is moved clockwise or anticlockwise as per thedirection for unloading. After few time, if there is no bag on the shaft, then it stops movingautomatically. Wireless switch is used to make the system on. The cargo is stacked temporarily in aplatform and then the cargo is taken by an artificial hand which lifts and moves the cargo in properstack. There is a sensor at some height of the stack to indicate the maximum stack height andaccordingly the next cargo is kept in next stack. The solution is intuitive and easy to use. This isvery useful in cargo management in railways, flights and trucks as well. It can save time for thelabors involved in load cargo into truck or unloading from truck. It is of significant importance incement or stone chips industries. The solution has a positive, good user experience. This kind ofmachine is very helpful in different industries in our country. This system can speed up thedelivery and storage process of cargoes. If the system is installed in different industries likecement, railway, airport, the workers should be benefited because of industrial automation. Thesystem ensures one time investment and low labor cost. The innovation is sustainable and scalable.If the system is properly maintained then it can be sustained. When the system is manufactured in alarge scale then the costing comparatively large but that can be affordable by the industry. Infuture, the system can be improved based on the stakeholder’s feedback.

Mr SK SUMANImage Delegate ID Theme Details


Research


Organisation : JIS COLLEGE OF ENGINEERING


Accidents are increasing due to tyre bursting while increasing in the temperature. of the bearingwhich results in wheel misalignment. Hence tyres with wheels comes out from the axial in movingcondition which results in accidents. Bearing failure can also be due to bearing buckling,scratches, nicks, dents, discoloration, corrosion and crack. This can be due to lack of lubricationor overheating etc. Also due to improper tyre pressure, harsh braking and increase in thetemperature of the tyre, tyre gets heated up causing tyre bursting which leads to fatal accidents.The main objective is to detect tyre temperature and wheel alignment deviation, thereby providingindication through audio-visual system which prevents accidents of the vehicle.

Mr MOHIT .Image Delegate ID Theme Details


Research

Category : Mechanical Engineering

Organisation : iit bhuDesignation : student

A new cross-flow heat exchanger flow arrangement is introduced, in a new cross-flow heat exchanger flow arrangement, which could be extensively used in compact heat exchangers currently used by the refrigeration and automobile industries. The proposed flow arrangement was developed using the general guidelines presented in Guo et al. (2002). The applicability demonstrates the influence of the “uniformity principle” of the temperature difference field (TDF) in the heat exchangers effectiveness. They tested several flow arrangements and demonstrated both theoretically and experimentally that a heat exchanger with a more uniform TDF distribution has higher effectiveness values. According to Guo et al. (2002), the thermal effectiveness of a cross-flow heat exchanger could be upgraded by a more uniform TDF. This can be achieved by, either redistributing the heat transfer area or rearranging the connections between tubes. In the present study, arguments related to the latter procedure have been used as the basis for the development of a tube side flow distribution so that the heat exchanger thermal performance is enhanced. It must be recognized that the uniform TDF is closely related to other norms that characterize the 2nd Law of Thermodynamics performance of the heat exchanger, such as the so-called HERN (“Heat Exchanger Reversibility Norm”), proposed by Sekulic (1990).

The proposed flow arrangement consists of two fluid circuits displayed in two tube rows, each with two tube lines which is similar to that proposed by Guo et al (2002). However, the actual arrangement is a two-rows-cross-flow heat exchanger, a configuration that is new to the best of the author’s knowledge. In order to evaluate its performance. The thermal effectiveness and the entropy generation in both cross-flow heat exchanger configurations have been computed and analysed by applying a recently developed computational approach, Navarro and Cabezas-Gómez (2005, 2007); and Cabezas-Gómez et al. (2007).

Ms Ashmika AgarwalImage Delegate ID Theme Details


Research


Organisation : AcSIR, AMPRI BHOPAL


High strength and fatigue resistant material are todays need for the transportation systems. Increase in product’s durability, decreasing fuel consumption, meeting emission norms, providing reliable product in market and ease in serviceability with low failure rates and low repair cost are in demand for material in almost every application in market today. FML proves to be a promising material for fulfilling these needs. This material started its journey with research in 1960s, most of the material development done by delft university in Netherlands, first commercialised with Airbus380 in late 1990s. Since then the r&d in this field has accelerated while exploring various raw materials, manufacturing process and increasing its performance. FMLs proves to be an advantageous material especially for application prone to high strain impact load and fatigue. Applications such as aerospace body structure and body armour are in commercial sectors. Further optimization with regards to the basis material used, performance, ease of manufacturability and low cost production & product is being studied by various people across the world. In India, the work has just started that too most of with collaboration with Research Institutes outside India. However, work done till now is limited to advance application at high cost. More durable products with new combination of metal alloys, natural fibre based composites with strong inter-laminar bonding, corrosion, temperature and fatigue resistant material is yet to be established. There is a necessity for developing a new class of hybrid FML having better mechanical, thermal, acoustic, corrosion resistant properties for possible application in ship buildin to replace traditional materials being used. This paper deals with the comprehensive database on work done do far on FML’s highlighting the future prospects with a special focus to address MAKE IN INDIA program while covering major technical areas of developments and challenges across the globe.

Mr Indrajeet ChavanImage Delegate ID Theme Details


Research


Organisation : Govt.Kalaniketan Polytechnic

College, JabalpurDesignation : Lecturer

Analytical Tools to Determine Transient Temperature Distribution in the Engine Wall for Stationary and Moving Conditions

Indrajeet Chavan a,*, Balaram Kundu b , Prokash Chandra Roy c

a Department of Automobile Engineering, Kalaniketan Polytechnic College, Jabalpur,482001, India b Department of Mechanical Engineering, Jadavpur University, Kolkata 700032, India c Department of Mechanical Engineering, Jadavpur University, Kolkata 700032, India

E-mail address: [email protected]

Abstract: This study presents a novel approach to determine the temperature of the engine using an analytical method that is more economical than the experimental method. The present analysis focused on the determination of temperature during one-dimensional transient heat conduction in the engine wall. The analytical analysis of one-dimensional transient heat conduction in the engine wall during stationary and moving conditions is done. The inner wall of the engine is heated with constant heat flux and the outer wall is exposed to a convective heat flux for surrounding cold fluid (coolant) required for cooling the engine. For the simplicity of the analysis, a new analytical scheme based on the Kantorovich approximate and Polynomial methods has also been established. Two different initial conditions have been used to consider an actual design variable. The analysis shows the significant similarity in temperature response obtained by Kantorovich approximate method as compared with the exact value obtained by the Separation of variables method. The effect of Thermo-physical parameters on temperature distribution has also been studied. A comparative investigation was carried out to understand temperature response in the engine wall during stationary and moving conditions of the engine. From the present analysis, it was observed that the temperature of the engine increases during the moving conditions. This was apparent because of the addition of enthalpy heat flux during the motion of the engine with a uniform velocity.

Keywords: Analytical; Engine wall; One-dimensional; Transient heat conduction

Ms Soumya JainImage Delegate ID Theme Details


Research


Organisation : Banasthali Vidyapith


This paper acquaints with the study of steady state laminar natural convection around heated elliptical plate placed inside a relatively cold circular enclosure subjected to varying number of elliptical plates (2, 3 and 4), Rayleigh number (104, 105, 106) and center to center distance between the elliptical plates(xc). The effect of these three parameters are observed and analyzed based on the simulation performed using Finite Volume Method (FVM). Heat transfer characteristics are analyzed for all the cases in terms of isotherms, streamlines and plots of average nusselt number with active enclosure walls and along the fringe of the inner cylinders illustrated in a graphical manner. Two dimensional study is followed by considering air as a fluid in the enclosure (Prandlt number=0.71). Eventually a conclusion is drawn based on the numerical simulation performed.

Dr V Phanindra BoguImage Delegate ID Theme Details


Research


Organisation : Vidya jyothi institute of technology


Mechanical behaviour of unit-cell based 3D printed lattice structures V. Phanindra Bogu1*, N.Srikanth1, Md.Imraz1, M.Shravan Kumar1, B. Prashanth1. 1 Department of mechanical engineering, Vidya jyothi institute of technology, Hyderabad *[email protected]

Abstract: 3D printing enables time and cost-saving in the product development process. It manufactures the complex lattice structures with fewer material consumptions and gives the necessary strength of the components. The unit-cell based lattice structures are used to improve the mechanical properties such as elasticity modulus and compressive strength. The present work analyses the mechanical behaviour of unit-cell based lattice structures such as FCC (face centre cubic), STAR and the COMBINED type. These lattice structures were modelled with a strut radius of 2mm and height to width ratio, i.e. H/W=1. Each structure was printed with a square base prism in 3D printer with Poly-lactic-acid (PLA) material. The compression test was performed to find the elasticity modulus (E), Ultimate compressive strength, total energy absorbed and strength to weight ratio. The mechanical properties of COMBINE structure are more significant than FCC and STAR type structures. The experimental values show promising results for mechanical applications. Keywords: 3D printing, FCC STAR, and COMBINED structures, elastic modulus, Compressive strength, Specific energy absorption.

References:

1. G. Gokhare, Dr. D. N. Raut and Dr. D. K. Shinde: A Review paper on 3D-Printing aspects and various processes used in the 3D-Printing. International Journal of Engineering Research & Technology (2017). 2. Antreas Kantaros1, Nikoleta Chatzidai1 & Dimitris Karalekas1: 3D printing-assisted design of scaffold structures. Int J Adv Manuf Technol (2016) 82:559–571. 3. Shiwpursad Jasveer*, Xue Jianbin: Comparison of Different Types of 3D Printing Technologies, International Journal of Scientific and Research Publications, Volume 8, Issue 4, April 2018.p7602.

Dr D.Thirumalaikumarasamy DuraisamyImage Delegate ID Theme Details


Research


Organisation : Government College of Engineering, Bargur


Magnesium (Mg) alloys have been widely used in aerospace, automobile and electronic fields, owing to their high specific strength and stiffness, free cutting and recycling. However, the application of Mg alloys is severely restricted because of low mechanical properties and poor resistance to corrosion. Friction stir processing (FSP) is developed on the basis of friction stir welding (FSW), during which microstructural refinement, homogenization and densification occur simultaneously. FSP has been demonstrated to be a good method to improve the mechanical property of Mg alloys through grain refinement. In this study, friction stir processing (FSP) was applied on the surface of the AZ31B substrate with different (1 to 3) passes. Metallographic examinations and scanning electron microscopy (SEM) were used to analyze the microstructure of the stir zones (SZs). The number of FSP passes was found to have a significant effect on the microstructure and strength of the specimens. The influence of the number of FSP passes on electrochemical properties of the SZs in magnesium in 3.5wt.% NaCl solution was analyzed via potentiodynamic polarization tests. Multipass friction stir processing of the specimens promoted grain refinement in the base metal and resulted in a uniform dispersion of the reinforcement particles. In addition, increasing the FSP pass number from one to three increased the density of the material. Also, corrosion resistance of the magnesium was severely influenced by the number of FSP passes and presence of reinforcement particles. While, corrosion performance of the materials was significantly enhanced as the number of FSP passes increased to two and three passes, a more number of FSP passes reduced the corrosion resistance of AZ31B materials. It was found that process parameters could be easily optimized to enhance the mechanical properties and corrosion resistance of the magnesium alloy during FSP. Keywords: Friction stir processing, Magnesium alloy, Corrosion

Mr ASHOKKUMAR MOHANKUMARImage Delegate ID Theme Details


Research


Organisation : GOVERNMENT COLLEGE OF

ENGINEERING ,BARGURDesignation : JUNIOR

RESEARCH FELLOW (DST- SERB SPONSORED

PROJECT)

Cold spray has revolutionized field repair of components and has had a profound effect on reducing sustainment costs in the aerospace industry, and similar savings can also be realized in several other important industry sectors including the petrochemical and nuclear power industries. It is a process in which solid powder particle are accelerated with high ballistic impingement on a substrate through a De-Laval Nozzle with a convergent-divergent geometry. The parameter selection based on the process optimization for gas jet nozzle that permits a suitable distribution of particle velocities for producing the desired physical properties of the deposit for any given material. Typically these parameters include the stagnation jet pressure (MPa), stagnation jet temperature (K), gas flow rate (m3/min), powder feed rate (kg/h), spray distance (mm), power consumption (kW), particle size (µm) Operational parameters are typically selected to achieve the most suitable coating for its intended application at the lowest operational temperatures and gas flows. In the cold spray the deposition of particle impact is associated with visco plastic deformation of the interacting bodies leading to (i) sequential compaction of the feedstock powder into a deposit and (ii) metallurgical bonding over a significant fraction of the particle-particle interfaces. Both of these processes are central to obtaining a dense and strong deposit. This study aims to provide the overview of the cold spray process, the recent understanding of deposition mechanism, and the related models and experiments, sprayability and parameter optimization for coating of light alloy materials.

Key Words: Cold Spray Process, Process Optimization, Coating, Deposition Mechanism References: 1. Y.S. Tao, T.Y. Xiong, C. Sun, L.Y. Kong, X.Y. Cui, T.F. Li, G.L. Song, Corros. Sci. 52 .2010 3191-3197. 2. H. Assadi*, H. Kreye, F. Gartner, T. Klassen, Acta Materialia. 2016 1-27.

Mr K.Arunkumar KarunamoorthyImage Delegate ID Theme Details


Research


Organisation : Government College of Engineering, Bargur


Degradation of surfaces of hydro turbine components caused by impact of abrasive particles carried by flowing water is a serious issue. A special case of providing protection to these surfaces is the application of the protective coatings on the surface of the material. Thermal spray coating provides a relatively thick coating layer for the protection from erosion. Thermal spray coating assures a low temperature of the treated elements, along with coatings producing high hardness and thickness of the order of a few millimetres. Among the different thermal spray coatings, HVOF is widely used thermal spray method due to the quality of coating produced in terms of porosity, and hardness. Porosity is the most important property, which influences considerably service life characteristics of coatings. In this investigation, Cr3C2-NiCr coatings were deposited on stainless steel by high velocity spraying process technique under different levels of oxygen flow rate, LPG fuel flow rate, stand-off distances and powder feed rates. Influence of process parameters on coating micro hardness studied using micro hardness tester. The results found that, oxygen flow rate greatly influences on the hardness of the coatings followed by other parameters such as LPG fuel flow rate, stand-off distances and powder feed rates. Keywords: Hardness, HVOF spraying; Cr3C2-NiCr coating

Dr Vamsi Krishna PasamImage Delegate ID Theme Details


Research


Organisation : NIT WarangalDesignation : Associate

Professor

Cutting fluids improves the product quality and production rate in machining. Solid lubricant nanoparticles are used to prepare vegetable oil based hybrid nanofluids and supplied in MQL mode in machining to avoid conventional cutting fluids and integrate the better characteristics of individual components. The performance of vegetable oil based hybrid nano cutting fluids is studied from their basic characterization and machining performance. In this work, multi walled carbon nanotube (MWCNT), boric acid (BA) and molybdenum disulphide (MoS2) nanoparticles are used along with vegetable oil based oils. Different combinations of hybrid nano cutting fluids are prepared for stable hybrid nano cutting fluids and found to be sesame oil, 15% content SDS surfactant and 1:2 (CNT/MoS2) hybrid ratio is optimum composition. In the second stage, concentration of nanoparticles in CNT/MoS2 (1:2) hybrid nano cutting fluids in sesame oil is studied by weight. Machining experiments are conducted in turning of AISI 1040 steel by varying concentration of hybrid nano cutting fluids. From the machining results, concentration 2 wt% of CNT/MoS2 hybrid nano cutting fluid has shown better performance than dry and conventional cutting fluid. The significant reduction in main cutting force, cutting temperature, surface roughness and tool flank wear is observed with use of 2 wt% of hybrid nano cutting fluid than pure CNT and Pure MoS2 nanofluids also. Optimization is performed for multiple responses by using desirability function analysis. Cutting force is found to increase with increase in cutting speed, feed and depth of cut and then slightly decrease with cutting speed of 100 m/min. Cutting temperature and tool flank wear are observed to increase with increase in cutting speed, feed and depth of cut. Surface roughness value is found to decrease with increase in cutting speed and it increased with increase in feed and depth of cut.

Mr Vivek JaiswalImage Delegate ID Theme Details


Research


Organisation : INDIAN INSTITUTE OF

TECHNOLOGY ROPARDesignation : Research

Scholar

This article reports the exploratory finding on the dissipation of paramagnetic and directingpendant droplet inside sight of interacting electric and magnetic fields. A pendant drop ofparamagnetic and electrically dynamic saline solution is allowed to vanish in a space with two fieldupgrades as referenced. The incorporation of solvated particles in a pendant droplet overhauls thescattering energy given interfacial osmosis desorption and including vapor dispersion layerrecharging as recommended by previous reports [1]. The evaporation characteristics seek after thecustomary D2 law [2], with a general augmentation in evaporation rate. As indicated by the pastassessments, an electric field prompts declined vanishing rates in pendant drop; however, theattractive field enables the dissemination to rate. In the present case, the solution of FeCl3 isused to frame a drop. The revelations uncover that of the two fields, the electric field has aprevailing impact, as the improved evaporation in the region of the magnetic field is noted todiminish on account of the neighboring of an associating electric field. The conventional dispersionis driven evaporating model [3] fails to foresee the evaporation rates under joined electric andmagnetic fields. The surface tension assortment in field condition moreover neglects to predict thedissipation elements. In this way, within thermo-hydrodynamics is inspected using PIV, and theinward stream flow is found to differ with the changed evaporation rate. A scaling assessment iscombining the effects of electro and ferrohydrodynamics, and their coordinated effort framework hasbeen proposed. The model can foresee adjusted scattering conduct.

Mr Viney GhaiImage Delegate ID Theme Details


Research


Organisation : Indian Institute of Technology RoparDesignation : PhD Student

The present study provides a novel method for designing and fabricating a multifunctional flexibleabsorber (flexorb) that can be used as a new coating material for ultra-high absorptionapplications. Untextured nanocomposite (UNC) is synthesized by reinforcing 1 wt. % of nanofillers[carbon nanotubes (CNTs), zinc oxide nanorods (ZnO) and iron nanoparticles (Fe)] inpolydimethylsiloxane (PDMS) matrix. Homogeneous mixture of these nanoparticles led to an ultra-highabsorption of more than 96 % in the broadband range (300-2000 nm). Subsequently, texturing wasperformed on the surface of UNC, which enhanced the absorption to more than 99 % in entireUV-Vis-NIR wavelength range. This increase in absorption is due to the multiple scattering of theincident beam on multiscale nanoparticles reinforced in PDMS along with the surface texture. Inaddition to this CNTs reinforced in flexorb provides better impedance matching which results inlower reflection losses from flexorb/air interface. Moreover, the TNC exhibited a better tensile,tear, shear and peel-off strength than pure PDMS and UNC. The fabricated flexorb has an advantage offlexibility which ensures that it can be deformed in variety of shapes without any damage orcreasing failure. Such a continuous uniform layer of ultra-black textured nanocomposite may findmany applications such as suppression of stray light in telescopes, architectural lighting, thermalimaging sensors, spectroscopy, aesthetic applications, satellite calibration sources, energyharvesting, camera lenses, automotive and IR Imaging systems.

Mr Vigneshwar VeeravaguImage Delegate ID Theme Details


Research


Organisation : SSN College Of Engineering


Despite the fact that the ocean plays a significant role in our ecosystem , we know very little about our ocean.

Underwater explorations is about making discoveries, searching for things that are unusual and unexpected. Findings made through underwater exploration are fundamental to reducing unknowns in deep-ocean areas and providing high-value environmental intelligence needed to address both current and emerging science and management needs.

One way to carry out underwater exploration is by deploying unmanned robots into the water that relay live videos of underwater. These robots are called as Remotely Operated Vehicles (ROV). ROVs are operated from the surface, enabling us to see underwater without us being under water. Additional equipment, such as a manipulator or cutting arm, water samplers, and instruments that measure parameters like water clarity and temperature, may also be added to vehicles to allow for sample collection.

This project aims at design optimization and development of the chassis of an ROV and incorporate a unique thruster configuration that enables the vehicle to operate at depths up to 100m and in fast flowing waters. The design aims to suite research class ROVs that houses a camera and no additional payload like a robotic arm or manipulator.

Design optimization is brought out by providing a hydrodynamic chassis that ensures water flows smoothly around the vehicle without creating any vortices. The proposed design also has a unique thruster configurations that provides more thrust than the standard 45° vectored configurations. Hence the lesser drag combined with better thrust output would enable the ROV to move in high water currents at depths upto 100m. By incorporating these changes, more difficult and arduous underwater terrains can be accessed and information about them can be collected, helping us to understand our ecosystem in a more intrinsic manner.

Mr Abhi VarshneyImage Delegate ID Theme Details


Research


Organisation : KIET Group of Institutions


In the Latest scenario, fuzzy logic control techniques have been utilizing a wide range of systems. This paper presentation shows how we can generate automatic-braking system(ABS) using Sugeno fuzzylogic. As we know braking systems are complex and non-linear which causes a little problem inbraking the vehicle, may cause road accidents due to unbalancing of the forces between the road andtires of the vehicle. Many control systems in the advanced vehicle such as automatic transmissions,engine control and many more realize superior outputs through the set of fuzzy logic-based controlrather than traditional control algorithms. ABS has a great contribution towards vehicle safety andspeed recognition using fuzzy logic.

Dr Thangarasu AImage Delegate ID Theme Details


Research


Organisation : Sri Ramakrishna Institute of

Technology, Coimbatore - 641 010

Designation : Associate Professor

Friction stir processing (FSP) was employed to fabricate Aluminium Surface Composites (SC) byreinforcing boron carbide (B4C) particles with AA6082 aluminium matrix alloy. The role of reinforcedparticles on the microstructure and mechanical behavior of the prepared surface composites wasstudied. The microstructure of the produced composite was examined utilizing optical microscopy,scanning electron microscopy (SEM) and electron backscattered diffraction (EBSD). The micrographs ofthe processed zone revealed fine grains and uniform dissemination of B4C particles with goodinterfacial bonding. Microhardness and wear resistance tests were conducted on the matrix alloy,FSPed matrix and produced surfaced composites with the different volume fraction of B4C particles. The microhardness and wear resistance showed higher values compared to the aluminium matrix andfriction stir processed aluminium without B4C particulates. It was seen that the wear resistance ofthe FSPed surface composite was improved significantly as compared to that of the AA6082 matrixalloy.

Mr mathivanan kImage Delegate ID Theme Details


Research


Organisation : Government college of engineering

Designation : Research scholar

In this paper, atmospheric plasma spraying technology was used to prepare the stellite coatings onto the substrate of AZ91D magnesium alloy. Three parameters of spray distance, input power and powder feed rate were optimized by the Design of Experiments (DOE) central composite rotatable design matrix, with the porosity of the coatings as object. Scanning electron microscopy and X-Ray diffraction was used to identify the phase composition and morphology of the coating. The results showed that the input power showed the highest effect on the porosity of the coatings, while the stand-off distance and powder feed rate exhibited the least influence. The potentiodynamic polarization and electrochemical impendence spectroscopy (EIS) results manifested that stellite coating prepared with proper spray parameters exhibited superior corrosion resistance with minimum porosity. Besides, the coating with lower porosity exhibited better corrosion resistance than the coating with higher porosity. Keywords: Magnesium alloy, Corrosion, porosity References: 1. Wood RJK, Speyer AJ 2003;256:545e56 2. Thirumalaikumarasamy D, Shanmugam K, Balasubramanian V. 2015;15:169e81.

Mr Pushpdant JainImage Delegate ID Theme Details


Research


Organisation : Oriental Institute of Science and

Technology, BhopalDesignation : ASSOCIATE

PROFESSOR

The present work aims to elucidate the influence of different diameter pedicle screw consideringvertebral bone degeneracy on lumbar section of spinal column. Vertebral segment L2-L3 is consideredand subjected to various loading conditions (axial compressive force and moment) in order tocharacterize the biomechanical aspects for optimum pedicle screw selection. A three-dimensional (3D)finite element (FE) model of lumbar vertebrae (L2-L3) was considered to analyze the numerous boneresponses and effect of various pedicle screw. Multi-sliced computed tomography (CT) images wereconsidered to generate surface and solid model of vertebrae L2-L3. Intact and implanted models withthree different pedicle screw diameter with four degeneracy conditions were adopted in finiteelement analysis. The von Mises stress distribution over intervertebral disc and bone-screwinterface was examined for various screw diameters and bone conditions. Results for flexion,extension, lateral bending and axial twist were compared among the various computational models. FEsimulated results have shown significant variations in von Mises stress distribution due to combinedloading conditions over bone degeneracy. Results shows that the 6.0mm pedicle screw diameterpossesses least stress values at bone-screw interface.

Mr TAPAS BISWASImage Delegate ID Theme Details


Research


Organisation : MCKV Institute of Engineering


Abstract: Selection of the best alternative powered vehicles is a complex decision-making problem.There has been a paradigm shift in the automotive industry caused by e-mobility which reduces greenhouse gas emission. In this paper, an integrated multi- attribute decision making (MADM) model isproposed for the evaluation of alternate fuel vehicles. Entropy method is used to determine theweights associated with the criteria, whereas Combined Compromise Solution (CoCoSo) method isemployed to rank the alternative vehicle considering different technical and operational attributessuch as greenhouse gas emission, fuel economy, vehicle range, accelerating time, annual fuel cost and vehicle base model cost. Fuel cell vehicle, hybrid electric vehicle, battery electric vehicle,plugs in hybrid electric vehicle and compressed natural gas bi-fuel vehicle are considered for thestudy. It has been found that battery electric vehicle out performs all other consideredalternatives. The validity of the results is verified by comparing by others popular MADM methods.Further, a sensitivity analysis has been conducted by changing the criteria weights to establish thestability of the proposed model.

Mr yogendra yadawaImage Delegate ID Theme Details


Research


Organisation : Rajiv Gandhi Institute of Petroliam

technology, Jais, Amethi, Uttar Pradesh


The phenomenon of erosion wear due to the cutting action of solid particles in solid–liquid mixture ?ows has been studied in a slurry pot tester. In the present study design and fabricate the modi?ed pot tester which has maximum volume capacity 75 litre and evaluate the erosion wear of the stainless steel SS410. The main components of the pot tester are slurry containing cylinder, fixture, two electric D.C. motor with electric panel of 2 hp and 1.5 hp power to rotate the specimen and stirrer holding shaft. Perform the erosion wear test of SS410 material operating at a 30 % by wt. slurry concentrations, relative velocity 4.2 m/s and 300 µm of erodent particle size. The slurry concentration replacement in 3 hrs, 6 hrs and 9 hrs time interval and find out the effect of erosion wear on SS 410 specimen material. We have concluded that the erosion wear of as received material SS410 in starting time of 3 hours slurry replacement is higher than the erosion wear of 6 hour and 9 hours of slurry replacement because the bigger size of erodent particles in starting 3 hours time interval.

Dr Javed ShaikhImage Delegate ID Theme Details


Research


Organisation : M.H. SABOO SIDDIK COLLEGE OF

ENGINEERING, MumbaiDesignation : Associate

Professor and HoD

A novel approach for micro-texturing of metallic surfaces Shaikh Javed Habib*; Mohammed Touhid Hasan Durvesh 1; Jyotsna Pankaj Gund2 *Associate Professor, Department of Mechanical Engineering, M.H. SABOO SIDDIK COLLEGE OF ENGINEERING8, Saboo Siddik Polytechnic Road, Byculla, Mumbai 400 008 1,2TE Student Department of Mechanical Engineering, M.H. SABOO SIDDIK COLLEGE OF ENGINEERING8, Saboo Siddik Polytechnic Road, Byculla, Mumbai 400 008 [email protected]

Abstract: Since last few decades, researchers are developing textured surfaces to enhance functionality e.g. self-cleaning, increased load carrying capacity and lubricant retention etc. of a given engineering component. Surface texture enables enhanced functional performance of the component in its working conditions. Inspired by natural textured surfaces offering unique properties, researchers are mimicking the textures of natural surfaces on the engineered components. As the texturing process involves development of micro/nano features on the given surface at large scale, the selection of a particular manufacturing process, its parameters and control plays a vital role. Hence the selection of most suitable process with optimum parameters for machining of micro/nano features with high productivity is highly desirable. Electron beam machining (EBM) being capable of generating micro and nano features, can be considered as one of the potential process for developing the tool that can be used for texturing applications. Also with the ability of Electrochemical Machining (ECM) to produce good surface finish, it makes ECM as the most suitable choice for developing hydrophobic surfaces through texturing. In the present article, an innovative approach for generating hydrophobic surface texture through development of micro-pillars and nano-hairs on metallic surfaces is proposed.

References: 1. Patel, Divyansh, V. K. Jain, and J. Ramkumar. "Micro texturing on metallic surfaces: state of the art." Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture 232.6 (2018): 941-964.

Mr amit BarkhaneImage Delegate ID Theme Details


Research


Organisation : Oriental institute of science and

technology Designation : student

Suspension system is the most important system in any automobile. The suspension provides the smooth ride and stability to the automobile. The typical suspension system of an automobile consist tires, springs and shock absorbers. The suspension system is designed according to a road conditions. But the modern suspension system has the ability to adjust itself according to the road conditions. Active suspension system is the modern suspensions system which consists a spring, dampers, control unit. Control unit consist sensors, Electronic control unit, and mechanism to adjust the sensitivity of the spring. Electric motor suspension is an active suspension system. It consist sensors to collect the data regarding road conditions, ECU to process that data and the sensitivity of the suspension is adjusted by the mechanism which is driven by electric motor. The main advantage of electric motor suspension system is that it reduces the work for dampers and hence the ride is smoother, and the suspension system performs well on high speeds. The most important advantage of this system is the cost of the active suspension system is reduced.

Mr Anurag SaoImage Delegate ID Theme Details


Research


Organisation : ISRODesignation : Scientist/Engineer

'SC'

The effect of gravity release in orbit poses severe challenges in meeting surface profile requirements of large reflectors with spacecraft. Usually, CFRP sandwich (solid) construction is used as preferred option for antenna reflectors of communication spacecrafts due to obvious advantages like high specific stiffness & better stability in orbit. With the increasing size of antenna reflectors the issues related to deformation due to gravity release become more severe. The deployable antenna reflector is supported in various support conditions & orientations during realisation & testing under gravity. These different support conditions & orientations cause deformation of antenna surface profile in different ways which may lead to loss in antenna performance. In order to mitigate the effect of 1g, an analytical estimate is carried out and based on this RF performance is evaluated with appropriate compensation. Also near zero ‘g’ condition will be simulated during testing of hardware. In this paper, the design of antenna reflector and the effects of gravity on antenna reflector with different support conditions & orientations are analytically studied. Also, the analytical results are experimentally established.

Ms Gauri SaxenaImage Delegate ID Theme Details


Research


Organisation : Banasthali Vidyapith, Rajasthan


Motion is a tool for analyzing the kinematic and dynamic performance of a mechanical system. Motionis fully integrated and embedded in CAD softwares as an add-in module for creating motion ofassembled entities. This paper acquaints with the multidisciplinary comparison of motion studyperformed on the two mated gears of similar aspects on AutoCAD and Solidworks designed as a partmodel. During the case study as a part of product development, two solid models of gears have beenmated on both the softwares and motion study is performed. Modeling has been done keeping thedesigning parameters the same on both the softwares. AutoCAD involves modeling and assembling on thesame platform whereas Solidworks generates two separate files for designing and assembly. During themotion study, a series of commands have been executed to study the motion. Rscript command has beenexploited for generating and running the loop in AutoCAD whereas Motion Manager is utilized forcreating and playing the animation. A 3D modeling comparison matrix has been developed whichcompares the looping feature of AutoCAD and Solidworks on the basis of multiple disciplines.Further, an independent size reducing coefficient ‘Kr’ has been defined for quantitativelycomparing the effectiveness of the process of product modeling to motion. The developed comparisonmay channelize the user to redesign the products and obtain a shorter and faster lead time toanalyze and develop the motion.

Dr ABHINAV DESAIImage Delegate ID Theme Details


Research


Organisation : S V NATIONAL INSTITUTE OF TECHNOLOGY

Designation : TEACHING ASSISTANT

Thermoacoustics, as can be understood from the name, is the science which deals with conversion of heat energy into acoustic energy and vice versa. This technology has multiple advantages over its peers such as this technology uses environment-friendly working fluids which eliminate concerns such as pollution, toxicity, negative environmental effects etc. This technology can use low-grade energy or a secondary heat source such as solar energy, industrial waste heat, the exhaust of an automobile, Eco fuel etc. Devices working on this technology can have no moving components at all which enhances reliability. Additionally, devices can be made-up of a very few and simple components made out of easily available material and they are comparatively easy to fabricate. And above all, this is a very young technology having great scope for innovative achievements. Citing such advantages thermoacoustic technology can be adapted as a great tool to reduce carbon footprint by generating and utilizing energy using thermoacoustics. Thermoacoustic technology can have vast application base such as cooling of high-speed electronics and infer-red detectors, microchip cooling, a refrigerator for storage of medical supplies, solar energy operated refrigerator of a cargo vehicle, electricity generation etc. which can be a great advantage in rural areas. Thermoacoustic technology can be harnessed in two ways. One is heat-driven acoustic energy generation that is thermoacoustic engine (TAE) and the other is acoustic energy-driven cooling that is thermoacoustic refrigerator (TAR). In addition to this primary bifurcation, TAE driven pulse tube refrigerator (TADPTR) and TAE driven TAR (TADTAR) are the other two applications based thermoacoustic devices. With TADPTR and TADTAR, cooling can be produced using heat that too without any moving components and adverse effect on the environment. The current work deals with the introduction of thermoacoustic technology, its advantages and technical limitations and applications of thermoacoustic technology. This also covers the working principle and components of thermoacoustic devices. This work further discusses the development of experimental setup and results from experiments carried out on thermoacoustic devices. Discussion on development work includes all four devices viz. TAE, TAR, TADPTR and TADTAR with their components, specifically TAE stack. During the experiments with thermoacoustic cooling devices, temperature difference capable of reaching the freezing temperature of the water has been recorded.

Mr Parth PatpatiyaImage Delegate ID Theme Details


Research


Organisation : Banasthali Vidyapith


The document tests the spatial precision of the additive manufactured (AM) bolt construction produced under industrial non-laboratory circumstances. One of the primary problems that hinder the use of additive manufacturing (AM) for bolt constructions is insufficient precision. We are using distinct methods, including Selective Laser Sintering (SLS) in a phenolic resin, Fused Deposition Modelling (FDM) in Poly Lactic Acid (PLA) and Digital Light Processing (DLP) in resin. The spatial precision of one of the complicated hybrid bolt structure is explored. A Co-ordinate Measuring Machine (CMM) performs the observations. The Additive Manufacturing (AM) components are shaped to be subsequently casted internally with glue (strengthened with fiber) to strengthen power and efficiency and are called 3D formwork. The document records the characteristics of the test sections, the semiconductor manufacturing methodology used, the test conducted and the subsequent dimension changes for each additive manufacturing (AM) method. In DLP, skilled additive manufacturing (AM) Indicated most precision. In SLS, there is less precision than DLP but more than FDM while FDM has least precision as compared to SLS and DLP. The FDM portion showed the reduced costs amongst the specialist AM for the specific situation research. Therefore the high quality production of SLS and DLP additives in plastics is close to reaching minimum precision requirements for bolt. Additive Manufacturing can therefore help to manufacture precise twisting constructions of bolt.

Mr Prakhar DoshiImage Delegate ID Theme Details


Research


Organisation : Acropolis Institute of technology and

researchDesignation : B.Tech

Student

Under the project title “Rapid concrete construction via 3D printing technology” , I aim to revolutionize the construction industry by introducing automation. The traditional construction industry is cost intensed, time intensed and human intensed which results in time delay, human interference and heavy costing. Through this technology my team would reduce the costing as we are using rapidly setting concrete which would reduce the costing of framework required in traditional process another benefit over traditional method would be as it will settle rapidly the time required would be reduced and there would be a boost in infrastructural growth. As the process is carried out using 3D printing technology it would be less tedious for humans and chances of error would decrease. There is a lot of research work done about the properties of concrete and 3D printing technology so what I have done is use the above information and make a product that would solve all the above problems. Further in the research my objective is to work on increasing the compressive strength of concrete by the help of mechanical engineering as all the engineering that could be done with respect to composition is done but there is less development over the mechanical devices that would extrude the material to the ground. Presently we are working over various steps that could be taken to increase the compressive strength.

Dr Bupesh Raja V.K.Image Delegate ID Theme Details


Research


Organisation : Sathyabama Institute of Science and

TechnologyDesignation : Professor,

School of Mechanical Engineering

Magnesium based alloys exhibit poor tribological properties and tends to lose their functional lifeprematurely. This problem is addressed through conventional surface treatment and coatings. Thesurface texturing and coating can be simultaneously achieved by carrying out under liquid laserablation. This gives the advantage of surface texturing with improved lubricant film adhesion tosurface without the unwanted thermal cracking and metallurgical changes associated with conventionalsurface treatments and coatings. In this experimental investigation, a magnesium alloy was subjectedto under liquid laser ablation in a 1-propanol having graphite particle of size 5 to 9 ?m stirred at1900 rpm by means of a magnetic stirrer. The under liquid laser ablation yielded nano structuredsurface topography that can promote wettability and the presence of propanol and graphite ensuredits impregnation on the surface of the alloy and thus improving its tribological properties. In thisstudy a Nd YAG fiber laser was used to etch the surface and achieve the under liquid ablation. Thesurface topography, average particles and roughness parameters of the magnesium alloy were studiedusing atomic force microscope (AFM). The average particle size distribution and the averageroughness of the topography were 281.50 nm and 44.26 nm respectively.

Dr Pradeep KUMARImage Delegate ID Theme Details


Research


Organisation : AcSIR-AMPRI Bhopal

Designation : PhD (CSIR-GATE)

Abstract:

Ti alloy are widely used in the orthopedic application as a bone implant due to their excellent bio-inertness, excellent corrosion resistance and high specific strength. In the present study Ti4Al4Co (wt%) alloy foam of 50 % porosity was prepared through powder metallurgy route and space holder technique using mechanical alloyed powders. Foams having similar porosity were heat treated in open atmosphere for different time (0h, 10 h, 20 h and 30 h) to investigate the compressive deformation and corrosion behaviours. It was found that due to heat treatment, oxide layer of Ti is formed on the surface of the foam. Thickness of oxide layer increases with time. Compressive stress-strain diagram indicate that plastic collapse stress considerably. Also, the energy absorption capacity changes with heat treatment time. Tafel plot shows that the value of Icorr significantly reduces with heating time, resulting improved corrosion resistance of the prepared form material. EIS curve also revealed that modulus of impedance and phase angle enhance due to heat treatment which prevent the foam sample to corrode in the electrolyte of simulated body fluid.

Mr Harish N MirajkarImage Delegate ID Theme Details


Research


Organisation : IIT BombayDesignation : Ph.D Scholar

: Knowledge of turbulent mixing of pure jets and forced plumes in a stratified ambient is importantfor pollution mitigation, effluent discharge and cloud dynamics. A fair number of experimentalresults on pure jets and forced plume in a uniform ambient are available in the literature [1].However, relatively less studies exists on the influence of stratification on the dynamics of aforced plume. This present study is an attempt to fill this gap by carrying out a detailedmeasurement and analysis directed at investigating the turbulence characterization and mixingbehavior of a forced plume in a linear stably-stratified ambient with source Reynolds number, =3100, where is the average flow velocity, D the jet diameter and is the kinematic viscosity.Stratification strength is characterized by the Brunt-Vaisala frequency , where is the verticaldensity gradient, is the bottom density and g is the acceleration due to gravity. In this paper,results concerning the forced plume and its characteristic behavior in near and far-field regions(z/D = 0 - 25) are presented. The mean and turbulence statistics of an evolving forced plume in astratified ambient, with stratification strength N = 0.4 s-1 , were measured using Particle ImageVelocimetry (PIV). The results are compared with that of a pure jet case (N = 0 s-1 and Re = 3100)to document the effect of stratification. From the experiments, some important results are asfollows: (a) the centerline velocity decays at a lower rate in case of a forced plume when comparedto that of the pure jet, and it abruptly becomes zero in the neutral buoyant layer unlike the caseof pure jet where the centerline velocity keeps decreasing, (b) axial velocity for a forced plume instratified ambient followed a Gaussian behavior, which is similar to that of pure jet, (c) theambient stratification increases turbulence and mixing in a forced plume compared to pure jet forthe same source Reynolds number, due to the combined effects of buoyancy and initial momentum, and(d) turbulent kinetic energy and Reynolds stress were higher for the forced plume case due to theeffect of buoyancy dominated momentum. The results from this study could be used as a test bed forvalidating numerical models related to shear-stratified flows.

Dr Sudipta PradhanImage Delegate ID Theme Details


Research


Organisation : Birla Institute of Technology Mesra,Patna

CampusDesignation : Assistant

Professor

Some study of Electromagnetic radiation of Material S. K. Pradhan a*, P. Kourb a Department of Mechanical Engineering, BIT Mesra, Patna Campus, Patna - 800014, India b Department of Applied Physics, BIT Mesra, Patna Campus, Patna - 800014, India * Contact Author’s e-mail address : [email protected]

Abstract: Electrical and electromagnetic effects associated with the deformation and fracture of materials have received continuous attention over the past several decades .The physics of plastic deformation of metals and alloys forms an important aspect of material research. Some significant variation in electromagnetic radiation (EMR) is observed during plastic deformation of aluminium material under tension. By changing diameter of specimen variation of EMR was observed. More charge is accumulated in larger diameter of metal, so the accelerated electric line dipoles give more EMR emission in larger diameter. Due to ductile material, the flow of charge & dipole formation is easily distributed within volume which results more EMR amplitude values.EMR emission concept is applied to several metal forming processes, behaviour of metal, crack propagation, machine life & their failure, prediction of earthquakes. References: 1. Misra,A.,Prasad,R.C.,Chauhan,V.S.,Kumar,R.;Mechanics of Materials.2010,42(5),505-521. 2. Chauhan,V.S., Misra,A.;Journal of Materials Science.2008,43,5634-5643.

Dr Vishal FrancisImage Delegate ID Theme Details


Research


Organisation : Lovely Professional University


The fabrication of complex geometrical components with desired performance characteristics have great industrial importance. In the past decade, Fused Filament Fabrication (FFF), one of the widely utilised 3D printing techniques has emerged as a promising candidate for fabrication of intricately shaped objects in short span of time. FFF provides a platform for fabrication of polymeric objects which are utilised for rapid tooling, functional testing and even for end-use components in a cost-effective way without any need of assembly. Due to layer by layer manufacturing, high complexity is achieved in FFF parts but on the other hand, it yields inferior properties compared to conventionally manufactured counterparts. Moreover, limited choice of available materials is another major constraint which further dampens the utilisation of FFF parts for end-use applications. This suggests a crucial need to improve the properties of the FFF printed parts. Therefore, it is important to investigate the prospects for enhancing the properties of FFF parts in order to enlarge its application domain. Nanomaterials are potentially capable to alleviate the constraint of the technology by altering the fundamental material properties of the FFF printing media. Utilising the attributes of nanotechnology with the well-known advantages of FFF process may open avenues for fabrication of complex parts with unique properties. Therefore, the aim of this research is to fabricate nanocomposites by FFF technique and to systematically study the effect of the stage-dependent addition of nanoparticles on structure, morphology, and properties of the FFF printed nanocomposites. In this study, three distinct approaches have been developed for nanoparticles inclusion in the printing material. These approaches are based on the stage of FFF process at which nanomaterials are introduced. Nanoparticles of clay are introduced at three different stages of FFF process namely, pre-processing, on-site and post-processing. It was found that stage dependent addition of clay nanoparticles in FFF printing material can enhance mechanical properties, improve dielectric and thermal properties and also enhances the surface properties. The nano particles interact in a different way with the printing materials in all the three stages of nanocomposite formation. The stage of nanoparticle addition in FFF process determines the internal structure, morphology and mesostructure of the printed nanocomposites and consequently influences their behaviour and properties. Investigations carried out during this work will serve to fill the gap in the knowledge of nanoparticle addition in FFF printing media.

Mr VENIGALLA SAILESHImage Delegate ID Theme Details


Research


Organisation : PVP Siddhartha Institute of

TechnologyDesignation : Student

Now-a-days there is an incredible demand of I.C engines. The main drawbacks of I.C engines is enormous in fuel consumption which leads to increase in fuel prices, pollution and shortage of fossil fuels. So need of alternative energy has become necessary. The main aim of project is the zero fuel consumption. The working principle of engine is the magnetic force principle, i.e., magnetic repulsion between same poles and attraction between opposite poles of two different magnets. When like poles of two different magnets come in contact with each other they repel, when opposite poles of two different magnets are separated they attract each other. This phenomenon is used in this electromagnetic reciprocating engine.

Dr SAURABH MANROImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : G.M.S. KHATTRA, LUDHIANA,

PUNJABDesignation : SCIENCE

MASTER

In this paper, by using Magical model of Mathematics among class 8th students, improvement amongstudents is tested and compare mean scores of Achievement test in Mathematics at Pre and Post stagesamong weaker students of class VIII studying in Govt. Middle School, Khattra, Khanna.

Mr Arvind GargImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : D A V College


In this article, we propose an optimized hybrid block method for integrating second order initial value problems in ordinary differential equations. The method is developed by considering a polynomial approximation to the true solution of the problem and imposing some interpolatory and collocation conditions. The method has fifth order of convergence. Further, it has good stability characteristics. Some numerical experiments have been carried out in order to demonstrate good performance of the method.

Ms Damini singhImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Doon

UniversityDesignation : research

scholar

The multi-scale modeling of blood flow in Human carotid artery numerically. Sarita Singh*, Damini Singh* Department of Mathematics, Doon University, Dehradun, Uttarakhand, India. E-mail addresses: [email protected], [email protected]

Abstract: The objective of this research is to develop a 3-dimensional numerical stimulation system for the study of arterial flow and arterial stenosis in carotid artery in more detailed aspects. For the whole arterial system a compliant model has been developed. For the carotid bifurcation 3D model is comprises with the 1D characterization for the rest of the arterial tree. The blood flow pattern is determined using Navier-Stokes equation as the governing equation while for the arterial wall elastic compliant model is implemented. The reduced 1D model solves the momentum and continuity equations with FEM Lax- Friendriches Flux method. The present simulation results agree well with the general flow pattern existing in the literature. . References: 1. Urquiza, S.A.; Blanco, P.J.; Venere, M.J. Comput.Methods Appl.Mech.Engrg. 2006,195, 4002 – 4017. 2. Formaggia, L.; Gerbeau, J.F.; Nobile,F.; Quarteroni, A. Comp. Meth. App. Mech,Engg. 2001, 191,561-582. 3. Wijayanti Budiawan,Inge.;Mungkasi, Sudi. Journal of Physics:Conference Series. 2017, 795, 012042. 4. Bharadvaj, B.K.; Mabon R.F.; Giddens D.P. Journal of biomechanics. 1982, 15, 349-362. 5. Bharadvaj, B.K.; Mabon R.F.; Giddens D.P. Journal of biomechanics .1982, 15, 363-378. 6. Quarteroni, A., Tuveri,M.; Veneziani, A. Computing and Visualisation in Science 2000, 2, 163–197.

Mr Kaja Bantha Navas Raja MohamedImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Sathyabama

Institute of Science and Technology


Abstract: The offshore wind announcements in India have been gathering pace in recent years. An investigation of wind speed with different heights is essential for wind power industries. In this study wind speed data from National Institute of Wind Energy (NIWE) for Gulf of Khambhat in India from November 2017 to November 2018 at different heights 40 m, 60 m, 70 m, 80 m, 87 m, 100 m, 107 m, 120 m, 140 m, 160 m, 180 m, 200 m have been assessed to determine the potential for wind power. NIWE has initiated first of its kind Light Detection and Ranging (LIDAR) based wind measurements to validate the potential at the preliminary demarcated zones. In this paper, we have framed a model for wind speed with different heights using regression analysis. The model is validated through extended power law. All analysis is carried out by Minitab software. Accuracy of the modeling is evaluated in terms of Root Mean Square Error (RMSE) and R2. Result: In this Paired wind speed at different heights analysis, we have chosen a pair of 200 m wind speed and 180 m wind speed as the best pair based on the R sq of 99.1 obtained. It can be seen that pair (200 m and 180 m) gives the minimum error and the most reliable pair compared to other pairs. According to this regression result, we generated the wind speed model at 200 m based on the wind speed at 180 m. 200m Wind Speed [m/s] = - 0.0618 + 1.01 *180m Wind Speed [m/s] ………………………... (1) According to the Wind profile power law, 200m Wind Speed [m/s] = 1.011 *180m Wind Speed [m/s] ……………… ………………….(2) Conclusion: The framed model performance was comprehensively investigated based on the wind speed data at different altitudes for every ten minutes over a period of one year. Based on the performance analysis with P-value and R2 value, we chose a pair of wind at different heights. The pair chosen is most reliable and error is minimum. This study also confirms the wind profile power law. References: 1. Turkan Y S, Aydogmus H Y and Erdal H, The prediction of the wind speed at different heights by machine learning methods, An International Journal of Optimization and Control: Theories & Applications, 2016, Vol.6, No.2, pp.179-187.

Mr AKHIL MITTALImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Gujarat Arts

And Science CollegeDesignation : Assistant

Professor

This investigations involve study of three dimensional nanofluid flow between two horizontalparallel plates. Pertinent effect such magnetic field effect is taken into consideration. Alsoeffects of thermal interfacial resistance, nanoparticle volume fraction, Brownian motion andnanoparticle size on thermal conductivity are considered. Calculation of viscosity was done takingaccount of micro mixing. System of differential equations is solved using Homotopy Analysis method.Effects of different parameters on fluid flow are discussed. It is observed that the skin frictioncan be decreased by decreasing Reynolds number or rotation parameter but observation is otherwise infor nanoparticle volume fraction. Nusselt number intensifies with with nanoparticle volume fractionand Reynolds number but it decays with increase of Eckert number or rotation parameters.

Mr RAHUL MEHTAImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Sardar

Vallabhbhai Patel Institute of Technology, Vasad


The present paper is concerned with the study of heat generation/absorption effect on unsteadynatural convective MHD Second grade fluid flow past an oscillating vertical plate in presence ofthermal radiation and chemical reaction. It is assumed that the bounding plate has rampedtemperature with ramped surface concentration and isothermal temperature with ramped surfaceconcentration through porous medium. Governing non-dimensional equations are solved using Laplacetransform technique and analytic expressions are obtained of velocity, temperature and concentrationprofiles. For both thermal plates, analytic expressions of Nusselt Number and Sherwood Number arederived and presented in tabular form. The effects of Magnetic parameter M, second grade fluid ?,Heat generation/absorption parameter H, thermal radiation parameter Nr, chemical reaction parameterKr in time variable t on velocity, temperature and concentration profiles are discussed throughseveral graphs.

Dr Anju SainiImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Graphic Era (Deemed to be University)Designation : Assistant

Professor

In this paper, we simulate and model breathing and compute particle depositions in the lungs. Herepresent a new model amongst others that explanations on behalf of the insolvable portion of thelungs and by the particular significance corrosion examine it by the sensitivity analysis.Particles, like; fine dust or medical aerosols, mainly generated systematized human lung geometriesand in patient-specific their depositions are simulated. In biomedical outlines, we initial presentportions of the mathematical and physical background through a prominence on fluid flows for abetter understanding. At that time we discuss in extra point of the numerical behavior of these typeof equations and application in a computational fluid dynamics software. We relate the outcomesregarding three core geometrical factors and fixed them into association by the particle depositionin a multiplicative model of consequent bifurcations in the lungs.

Dr HARSHAD PATELImage Delegate ID Theme Details


Research

Category : MathematicsOrganisation : Sardar

Vallabhbhai Patel Institute Of Technology,


In this study, two dimensional mixed convective MHD stagnation point flow of Carreau fluid past aninfinite plate in the porous medium is studied. The effects of cross-diffusion, thermal radiation,heat generation, and chemical reaction are considered. The governing partial differential equationsare remodeled into ordinary differential equations by using similarity transformation. HomotopyAnalysis method is employed to solve the system of ordinary differential equations. The effects ofdifferent prevailing parameters on velocity, temperature and concentration profiles are showngraphically which is obtained from the Mathematica code. The numerical values of the skin friction,Nusselt number, and Sherwood number are also presented in a tabular form. We have also presented thenon-dimensional fluid velocity, fluid temperature and concentration for both cases Newtonian Carreaufluid (n=1) and Non-newtonian Carreau fluid (n >1 or nparameter through the graph. It is depicted that, velocity profiles decrease via mixed convectionparameter ?, buoyancy force parameter N for the case of Newtonian Carreau fluid (n=1) whereas, inthe case of non-Newtonian Carreau fluid those parameter has reverse effects on it. It is also seenthat when (n=1) no effects of local Weissenberg number on all profiles whereas, when (n=3) localWeissenberg number tends to improved velocity profiles.

Mr Surajit MondalImage Delegate ID Theme Details


Research

Category : Energy Engineering

Organisation : University of Petroleum and Energy

Studies, DehradunDesignation : Research

Scientist

Today’s dearth of energy is one of the biggest concerns in front of the human. Increasingpopulation demands more energy, hence burden on presently used non-renewable sources of energy.These non-renewable sources such as fossil fuel, coal are expectedly to finish up. Environmentpollution is also one the major problem while extracting the energy from these sources. Biomass isanother substitution of energy dependence on the non-renewable source. Probably it has the capacityto overcome present requirement of energy. Bio-fuel from non-conventional oil containing seeds isone of major search area of biomass energy. Extraction of oil from these seeds is possible viathermochemical and biochemical ways. One of the major advantages of biomass is a negligible amountof sulfur content in the fuel or oil. The increasing energy demand of a rapidly growing populationhas rekindled the interest of humankind in the use of biomass as a source of energy. The mainfactors behind this resurgent interest in biofuels are the fast-depleting fossil fuel reservoirs andconcerns regarding climate change. The proper choice of technology for conversion of biomass intoclean-burning fuel is essential for sustained use of biomass as a source of energy. Variousthermochemical conversion processes such as combustion, hydrogenation, liquefaction, gasification,and pyrolysis have been utilized to extract various energy products from biomass. Even thoughpyrolysis, of all the thermo-chemical processes, is still in a preliminary stage of development, ithas received special attention in our present energy scenario as it can convert biomass into avarious liquid, solid and gaseous products. The use of solar energy provides a renewable source forpyrolysis, which gives it an edge overuse of thermal energy.

Mr AMIT KUMAR SINGHImage Delegate ID Theme Details


Research


Organisation : IIT GUWAHATI

Designation : SENIOR RESEARCH FELLOW

Hydrogen fuel cells work by instigating stored hydrogen to react with oxygen in the air, producingelectricity and water. However, the generation of pure hydrogen fuel can be a challenging problem.The large-scale production of the hydrogen gas is mostly achieved by steam-methane reformingprocess. The major drawback of the steam reforming is that – (i) it takes place at hightemperature and thus requires external heat energy to maintain the elevated temperature and (ii) theprocess results in the emission of greenhouse gases as a by-product of the reaction. Furthermore,hydrogen storage and transportation are expensive and requires exclusive tanks to store the gas atenormously high pressure. To address this issue, we report self-propelling Ferrobots composed of acollection of iron nanoparticles (FeNPs), for rapid on-site generation of pure hydrogen gas usingformic acid as fuel. Instead of storing hydrogen gas in bulky pressurized tanks, the motileFerrobots could be easily deployed into aqueous formic acid solutions for on-demand release of thepure hydrogen gas, devoid any of greenhouse gases, at room temperature. To demonstrate theproof-of-concept, the reactive Ferrobots were employed to power a portable toy fan equipped with aPEM fuel cell. The pure hydrogen gas required for the PEM fuel cell was generated through thereaction of the formic acid solution with self-propelling Ferrobots, whereas, the oxygen gas wasproduced by catalytic decomposition of peroxide fuel using the same Ferrobots. The as-generatedhydrogen and oxygen gases directly fed from the reaction chambers to the fuel cell electrodes togenerate electricity and thus power the electronic toy fan. The advantage of this type ofmicromotor-mediated system is that liquid fuels are used for on-site hydrogen release, and thereforegas storage will not be prerequisite in the near future.

Mr Dudul DasImage Delegate ID Theme Details


Research


Organisation : Indian Institute of Technology

GuwahatiDesignation : PhD student

For optimum utilization of solar energy the collection systems needs design improvement throughresearch. Due to stochastic behaviour of solar irradiance, it is difficult for the researchers toprovide a clear comparison of developed solar collectors based on performance parameters underoutdoor conditions. In this work experimental evaluation of a newly developed PV/T collector havingdensely placed copper tubes attached to the backside of PV in serpentine fashion is presented underindoor conditions. The work also discusses design criteria and characterization of indigenouslydeveloped low cost solar device testing. In the present design of PV/T tubes are directly glued tothe back of PV to avoid additional surface contact resistances while using a sheet-tubeconfiguration. The experiment was performed maintaining a fixed distance of 40 cm between the lightsource and test plane where an average of 625 W/m2 is obtained. The effect cooling is studied bychanging the fluid flow rate in the collector from 0.01 to 0.074 kg/s. The PV/T is evaluated basedon energy analysis method.

Dr Ulaganathan MANIImage Delegate ID Theme Details


Research


Organisation : CSIR-CECRIDesignation : Ramanujan

Fellow

Redox Flow Battery- A High Energy Storage Technology: Current Scenario in India M. Ulaganathan* Electrochemical Power Sources Division, CSIR-Central Electrochemical Research Institute (CSIR-CECRI), Karaikudi-630003, India Contact Author’s e-mail address: [email protected]

Abstract: Renewable and sustainable sources are considered as alternatives for fossil fuels to meet the global energy demand and hence reduce CO2 emission. Solar and wind energy are primary resources of renewable energy but they are intermittent in nature. Among the available technologies for electrochemical energy storage, redox flow battery is a potential candidate owing to its numerous merits such as high energy density, long cycle life, eco-friendliness and low cost and can easily scale up to few MWh range. Globally, the RFB has studied extensively and already commercialized successfully. However, in India, the research and development activity particularly in this RFB technology is very scant. At the same time, India is a rich country in terms of the availability of renewable resources. Therefore, this RFB technology will play a vital role in the energy storage technology if it is executed successfully. In the present presentation, the author wishes to focus on the fundamentals and the status of RFB in the Indian scenario.

References: 1. M. Ulaganathan, V Aravindan, Q Yan, S Madhavi, M Skyllas?Kazacos, TM. Lim. Recent advancements in all vanadium redox flow batteries. Advanced Materials Interfaces, 3(1)(2016) 1500309.

Dr Jwngsar BrahmaImage Delegate ID Theme Details


Research


Organisation : Pandit Deendayal Petroleum

UniversityDesignation : Assistant

Professor

The region Baramura is characterized by huge anticlines, normal faults and abnormally pressuredformations which causes a wide margin of uncertainties in wildcat well planning and design.Therefore a proper well design is essential in such a region to prevent blowout. Pore pressure playsan important role to design a safe and economical well in such a high pressure and temperaturereservoir. A hybrid model is developed to predict pore pressure from seismic velocity data. Anexcellent match with pore pressures estimated from RFT pressure data and predicted by hybrid modelalong with modified Eaton’s method are observed in this research work. Pore pressure predicted byhybrid model indicate result up to the 6000 m, which is up to the basement rock. The predicted porepressures by hybrid model are used as an input to calculate the fracture pressure by Hubbert andWillis method, Mathews and Killy method and modified Eaton’s method. Equivalent mud weightselection is done using median line principle with an additional 0.3ppg, 0.3ppg and 0.2ppg Swabpressure, Surge pressure and safety factor respectively for calculation of all casing pipe. Casingsetting depths are selected based on pore pressure, fracture pressure gradients and mud weight. Herefour types of casing setting depths are selected: conductor, surface, intermediate and productioncasings at 100ft, 6050ft, 15500ft and 18500ft respectively. The casing policy is selected based onburst pressure, collapse pressure and tension load. For each casing kick tolerance in bbl isdetermined from kick tolerance graph to prevent the blowout. Finally a safe and economical well isdesigned on the top of Baramura anticline along with target depth selection, casing setting depthselection, casing policy selection and kick tolerance which gives a clear picture of well planningon the top of anticline in pore pressure point of view.

Mr Himanshu VaishnavImage Delegate ID Theme Details


Research


Organisation : Mohanlal Sukhadia University Udaipur

Designation : Senior Research Fellow, DST

INSPIRE

The solar energy has the paramount potential to fulfill present thirst for energy and theprerequisite for innovation of clean and eco-friendly energy technologies. In this research domain,developing solar cells is one of the best approaches to convert solar energy into electrical energybased on fundamentals of photovoltaic e?ect. Wherein, thin-film solar cell technology has aworldwide reputation in field of thin-film community and also paves a way for innovative solar celltechniques in large scale industrial manufacturing applications. Recently thin-films have progressedinto a sophisticated way to increase performance and esthetic value for making new functional solarcell devices. With advent of new materials for thin-film solar cells, have made solar cells morefeasible to be employed in terms of device design, fabrication and efficiencies for long termdeployment as these provide solution for today’s concern of energy crisis. According to globalstatus report, the estimated renewable energy share of global electricity production by end of 2016using solar photovoltaics is just 1.5% of total production and it is prime necessity of nation’syouths that this percentage of production of electricity employing photovoltaics need to increase inorder to meet with the current demands of our nation. In line to this, CdTe and CdSe materials haveemerged as arguably the most promising next-generation thin-film solar cell technologies as thesematerials can be deposited into thin films at low temperature and provide high efficiency, low-costphotovoltaics, and hence present exciting opportunities for innovative device architectures. Acertified 22.1 % efficiency has already been achieved for CdTe technology and currently it leads thethin-film photovoltaic industry. However, some technical obstacles still exist which keep thistechnology away to approaching towards maximum predicted theoretical efficiency of ~ 30%. And thisfact opens up great opportunity to nation’s youths for further research.

Mr RAVI SHANKAR KUMARImage Delegate ID Theme Details


Research

Category : Energy EngineeringOrganisation : RAJIV

GANDHI INSTITUTE OF PETROLEUM TECHNOLOGY

Designation : PhD Scholar

The ongoing demand of hydrocarbon triggered the decline of oil reserves globally and turned into a major challenge for the producers concerned with the recovery of remaining (residual) crude oil from reservoirs. Thus, improving oil production from current reservoirs holds the key to meet the current and near future challenges of global energy demands. Nano-assisted enhanced oil recovery (N-EOR) is one of the techniques which can considerably improve the oil recovery factor of the trapped oil. Nanofluid, a colloidal suspension of nanoparticles (NPs) (size ~ 10-9 m) in polyacrylamide solution (base fluid) may enhance the oil production by governing the matter of facts at nano scale level. However, complex reservoir fluids are highly saline; which greatly affects the physical-stability of nanofluid and limits their efficacy for subsurface applications resulting in premature settlement and possibly may block the reservoir pores during flow through reservoir pores, turns into reduction on N-EOR application, not yet reported, nevertheless, a key parameter for high saline reservoirs. Therefore, a novel synthesis of nanofluid consisting of SiO2 in the base solution of polyacrylamide is proposed in this study. An anionic surfactant sodium dodecyl sulfate (SDS) in varying concentrations are used to curtail the effect of saline environment on nanofluid. The physical stability for the formulated nanofluids is discussed using visual appearance and dynamic light scattering (DLS) followed by morphological analysis of the agglomerated NPs in saline environment. The rheological stability of the synthesized nanofluid was investigated in saline environment. Moreover, the formulated nanofluids are then investigated using oil recovery experiments for nano-assisted (N-EOR). The surface-coated NPs in nanofluid attended maximum recovery of more than 60% in the saline environment (5 wt% NaCl) while it was 70% for saline free environment. The surface-coated NPs in the nanofluid provides a stable nanofluid for a longer duration by maintaining nanometer size is interesting and challenging to avoid early particle aggregation thusly showed incremental oil recovery. This study discusses the novel fabrication methodology of a stable nanofluid using colloidal aspects for subsurface oilfield applications where formations salinity becomes a major challenge during flow through porous and permeable media; would be fortune made for N-EOR in saline reservoirs.

Mr arun sankar nellaiyappanImage Delegate ID Theme Details


Research


Organisation : Sri Venkateswara College of

EngineeringDesignation : Proprietor

Abstract: Polymer electrolyte from scrap PVC blend using organic solvents complexed with lithium salts was formed using solution casting method. Characterization of the film was done using Thermo Gravimetric Analysis (TGA), Impedance spectroscopy tests, Fourier Transform Infrared spectroscopy (FTIR), Differential scanning calorimetry (DSC), Scanning electron microscopy (SEM), Dielectric Spectroscopy, Dynamic Mechanical Thermal Analysis (DMTA). The dielectric measurements of the film were carried out as a function of frequency at various temperatures. The dielectric behavior was analyzed using dielectric permittivity (??), dissipation factor (tan ?) and electric modulus (M?) of the samples, to enhance the strength of the film a plasticizer has been added where the result was increased mechanical strength along with reducing crystallinity of the film. X- ray diffraction test was carried out to study the amorphous phase of the polymer. With further study we found that the PVC can also act as a stiffener for the electrolyte due to it immiscibility with the plasticizer. At present polymer electrolyte are prepared using different weight ratios of plasticizer and PVC and constant weight percentage of lithium salts. Same tests were carried out for the other films with different weight ratios of PVC and found out that the ionic conductivity of the sample was in the order of 10-6 Scm-1 . This process leads to decreasing the electrolyte cost in the batteries which comprises 16-18% of the overall battery cost. Hence the cost of the battery will also get reduced. The whole process is done in an eco-friendly way, reducing landfill and incineration of plastic wastes. The electrolyte preparation method entails low energy consumption and lesser environmental impact. References: 1. Dielectric behavior of PVC-based polymer electrolytes by S. Ramesh, A.H Yahaya, A.K. Arof. 2. FTIR and conductivity studies of PVC based polymer electrolyte systems by S. Rajendran, T.Uma.

Mr Mithilesh RakhdeImage Delegate ID Theme Details


Research


Organisation : PRSUDesignation : Student

The green buildings with ground source heat pump system concept which includes the renewable sources used for the construction. It reduces the cost and pay back within 10 years. The systems used are solar photovoltaic, solar distillation, solar water heater, solar cooker, geothermal heat pump etc., this sytems require less maintenance and high savings. This system concept is very much useful in keeping the environment clean which on a certain view even increases the life period of building. The choice of products used to build, renovate and operate structures has a significant impact on the environment. Wood products have less embodied energy, are responsible for lower air and water pollution, and have a lighter carbon footprint than other commonly used building materials. A home which can function using an optimum amount of energy, consume less water, conserve natural resources, generate less waste and create spaces for healthy and comfortable living, as compared to conventional buildings, is a green buildings with ground source heat pump system . Conventional methods of building use tremendous quantities of material, many of them non-renewable and toxic, and pay little attention to the impact the building has on the environment. Green buildings with ground source heat pump system, not only reduce these impacts but are also healthier and consume less energy saving money in the long run. When a number of green buildings are located in proximity, they would create a green zone, providing much healthier environment and minimize heat-island effect. The ultimate aim will then be to create many such areas, which would help the towns and cities and therefore the nation in reducing total energy requirement and also the overall global carbon footprint. The ground below the parking area, roads, garden etc. can be utilized for air conditioning in homes.

Dr alok kumar shrivastavaImage Delegate ID Theme Details


Research


Organisation : mahatma gandhi central universityDesignation : assistant

professor

Augment photosynthesis of salt tolerant strain Fremyella diplosiphon for biofuel production

Alok Kumar Shrivastava*

Summary

. Fremyella diplosiphon is a fast growing cyanobacterium, shows extreme regulation of photosynthetic pigments phycoerythrin and phycocyanin synthesis, grows heterotrophically in the dark, and have little tendency to clump to surfaces during their growth in liquid culture. Fremyella diplosiphon have potential to grow in a wide range of light intensities. Photosynthesis is the process to convert sunlight into stored chemical energy, is highly inefficient for biofuel production. Hence there is requirement to enhance photosynthesis of salt tolerant strain. Rubisco of Fremyella diplosiphon play an important role in central carban metabolism that fix CO2, which has lower affinities with CO2. In view of the above problem, a CCM is developed in which two carban fixing enzymes rubisco and carbonic anhydrase are stored in organized micro-compartments carboxysomes. Till date there is no any work where CCM gene used to improve the photosynthesis of Fremyella diplosiphon which is requirement of high biofuel production. Taking recourse to above my proposal would be to improve the quality of salt tolerant strain of Fremyella diplosiphon in term of photosynthesis which will be used to synthesize more photosynthate in naturally available salt water

Dr Subhasis RoyImage Delegate ID Theme Details


Research


Organisation : University of Calcuttaa


Titanium dioxide and KMnO4 composite film on FTO glass as a working electrode for solar cell application Shyamal Datta1, Subhasis Roy* Department of Chemical Engineering, University of Calcutta, 92 A. P. C. Road, Kolkata 700009, India Contact Author’s e-mail address: [email protected]

Abstract: The present study aimed to develop and performance analysis of DSSC solar cell based on TiO2/KMnO4 composite active layer. To prepare TiO2/KMnO4 paste, the mixture of TiO2/KMnO4 powder (KMnO4 content: 2, 6 and 10 wt%) was dispersed into the binder (Benzyl alcohol).TiO2/KMnO4 composite films were successfully deposited on the FTO glass which act as working electrode by doctor blade method. 2wt %, 6wt % and 10wt % samples of TiO2/KMnO4 were prepared for thin film deposition on FTO substrate. Optical properties, surface morphology and crystal structure were investigated by UV-Vis spectroscopy, scanning electron microscopy (SEM) and X-ray diffraction (XRD) successfully. Optical analysis showed TiO2/KMnO4 with 2wt %, 6wt % and 10wt% film have a direct band gap of 1.9eV, 1.7eV and 1.45eV respectively. An electrolyte containing iodide/ triiodide (I-/I3-) was used to transport for redox mediator between two electrodes. The working electrode was assembled into a sandwich with graphite counter electrode. The performance of these fabricated were tested under simulated AM 1.5G solar illumination using 100mW/cm2. The highest efficiency 2.04 % was achieved for 10wt% TiO2/KMnO4 composite film. Finally compares were done with and without KMnO4 addition. The result reveals that KMnO4 addition increases the power conversion efficiency of the DSSC solar cell. Keywords: Thin film, solar cell, composite layer, doping.

1Presenting author *Corresponding author

Mr Domesh sahuImage Delegate ID Theme Details


Research


Organisation : Pt.RSUDesignation : Student

The green buildings with ground source heat pump system concept which includes the renewable sources used for the construction. It reduces the cost and pay back within 10 years. The systems used are solar photovoltaic, solar distillation, solar water heater, solar cooker, geothermal heat pump etc., this sytems require less maintenance and high savings. This system concept is very much useful in keeping the environment clean which on a certain view even increases the life period of building. The choice of products used to build, renovate and operate structures has a significant impact on the environment. Wood products have less embodied energy, are responsible for lower air and water pollution, and have a lighter carbon footprint than other commonly used building materials. A home which can function using an optimum amount of energy, consume less water, conserve natural resources, generate less waste and create spaces for healthy and comfortable living, as compared to conventional buildings, is a green buildings with ground source heat pump system . Conventional methods of building use tremendous quantities of material, many of them non-renewable and toxic, and pay little attention to the impact the building has on the environment. This system, not only reduce these impacts but are also healthier and consume less energy saving money in the long run. When a number of green buildings are located in proximity, they would create a green zone, providing much healthier environment and minimize heat-island effect. The ultimate aim will then be to create many such areas, which would help the towns and cities and therefore the nation in reducing total energy requirement and also the overall global carbon footprint. The ground below the parking area, roads, garden etc. can be utilized for air conditioning in homes.

Prof Sukhendu JanaImage Delegate ID Theme Details


Research


Organisation : Meghnad Saha Institute of Technology


C60 Embedded Diamond-like Nanocomposite Thin Film Deposited by PECVD Method for Anti-reflection Coating on Solar Cell S. Jana 1,2,*, S. Das 1,2, D. De1, U. Gangopadhyay1, A. Mondal2, N. Shakti3 1 Meghnad Saha Institute of Technology, Kolkata – 700150, India. 2 Indian Institute of Engineering Science and Technology, Shibpur, Howrah -711103, India. 3 Indian Institute of Technology, New Delhi-110 016, INDIA * Contact Author’s e-mail address: [email protected]

Abstract: Anti-reflection as well as passivation coating has a major role to enhance the efficiency of solar cell. Different optical coatings are used to minimize the reflection from silicon based solar cell like SiOx, Al2O3, SiNx, etc[1]. However, the SiNx is widely used as ARC in silicon based PV Industry [2]. But, two highly toxic gasses ammonia and silane are used to deposit SiNx. Moreover, the passivation effect is degraded during cell fabrication process [3]. Diamond-like Nanocomposite (DLN) is a new kind of material in amorphous carbon family [4-5]. The DLN film has much lower internal stress (~MPa), high thermal stability (6000C) and higher optical band gap (2.5eV-3.5eV) compare to DLC film [5-6]. The film properties could be varies in wider range by changing precursor and deposition parameters [5 -7]. In our previous paper, we have reported the ARC properties DLN film deposited by PECVD using precursor HMDSO [8]. In this present study, DLN thin film has been deposited using mixed precursors of HMDSO and HMDSN. The effect of high thermal treatment (up to 8500C) on structural and optical properties has been investigated. We first reported the self-growth of nc-C60 embedded DLN thin film by PECVD process. The refractive index and optical bandgap were around 1.89 and 4.10 eV respectively. The minimum reflection from DLN coated solar cell was less than 1% at 620 nm. The DLN coated solar cell efficiency was increased absolute 2% compared to SiNx due to superior ant-reflection and passivation properties.

References: 1. N. Sahouane; et al, Energy Procedia, 2014, 44,118-125. 2. Y. Lee; et al, Nanoscale Research Letters, 2012, 7, 50. 3. J. Dupuis; et al; Thin Solid Films, 2008, 6954-6958. 4. V.F.Dorfman; Thin Solid Films, 1992, 212, 267-273. 5. Š. MEŠKINIS; et al; ELECTRONIC AND OPTICAL MATERIALS, 2011, 17, 4. 6. U. Gangopadhyay; et al, Journal of Renewable and Sustainable Energy, 2013, 5, 031607. 7. S. Jana; et al, Applied Physics A, 2014, 114, 965–972. 8. S. Jana; et al; Materials Research Express, 2018, 5, 2.

Dr Biplab PaulImage Delegate ID Theme Details


Research


Organisation : Linköping University


For harvesting power from the hot curved surfaces (e.g. hot pipe) and for near room temperaturewearable applications the development of fully-inorganic flexible thermoelectric thin film materialsis essential. In particular, the fully-inorganic flexible films are important for applications inhostile environments, e.g. wearable applications for fire workers. The organic materials, despitewith advantage from their inherent flexibility, are not suitable for sustainable performance, asthey cannot sustain high temperature and degrade over time. On the other hand, the inorganicmaterials offer sustainable performance, however, the challenge is associated with their inherentrigidity, restricting their use for flexible applications. Here, the growth of p-type Ca3Co4O9 andn-type ZnO thin films on flexible mica substrates are reported. An interesting two-stepsputtering/annealing method has been implemented to grow the Ca3Co4O9 films on flexible micasubstrate. The CaO-CoO films are first reactively cosputtered from the elemental targets of Ca andCo, followed by annealing at 700 ?C to form the final phase of Ca3Co4O9. The advantage of thistechnique is that the sputtering from elemental targets allows faster deposition and it allows thenanostructural tailoring of the films. The final nanostructure in the postannealed Ca3Co4O9 filmsdepends on the pattern of structural evolution during thermally induced three-stage phasetransformation, while guided by the surface and strain energy and the distributions of CaO and CoOphases in the as-deposited films. For n-type component, the Ga-doped ZnO films are deposited on micasubstrates by atmospheric pressure metalorganic chemical vapor deposition (APMOCVD). Both theCa3Co4O9 and ZnO films are bendable to the bending radius of 14 mm, while sustaining the high powerfactor, above 0.1 mWm-1K-2 in a wide temperature range, from room temperature to 400 ?C. With thishigh power factor mechanically flexibile Ca3Co4O9 and ZnO films open a new opportunity forfully-inorganic flexible thermoelectrics.

Dr Praveen KUMARImage Delegate ID Theme Details


Research


Organisation : IACS KolkataDesignation : Assistant

Professor

The ever increasing demand for renewable and clean energy sources has prompted the development of novel materials for photoelectrochemical (PEC) water splitting, but efficient solar to hydrogen conversion remains a big challenge. TiO2 is one of the most favorable materials despite having low efficiency, however, the search for the ideal materials for photo-anode/cathode is still going. III-nitrides have emerged efficient potential materials for photoelectrodes, however, due to the unintentional n-type nature (nitrogen vacancies) and built-in-potential at the electrode and water interface, the full potential has yet not been achieved. Various approaches to modify the surfaces have been reported to improve the overall PEC efficiency, however, with limited success. Three recent approaches I will present, where we have modified III-nitride surface with InN quantum dots (QDs), 2D materials and bacteriorhodopsin (bR), a natural proton pumping photosystem. The InN QDs lowers built-in potential at the interface of InGaN photoanode and electrolyte, whereas for bR/GaN nanowall network bio-nanohybrid) enhances the charge separation and hence finally water splitting efficiency. The results manifest a more than 1.5 fold efficiency enhancement for hydrogen evolution by the InN QDs, with incident photon-to-current-conversion efficiency (IPCE) of 44% at a wavelength of 550 nm, and applied bias photon-to-current efficiency (ABPE) in two-electrode configurations of 4.5 % at 0.2 V applied potential. Further, the synergistic effect in bR/InGaN NWN photoanode gives rise to a largely enhanced applied bias photoconversion efficiency (8%) and photocurrent density (33 mA/cm2 at an onset 0.5 V vs RHE). It is worth mentioning that the photocurrent density of bR/InGaN NWN, to the best of our knowledge, is superior to previously reporting bR-based photoanodes and bio-photoelectric devices reported till today for solar-to-hydrogen fuel generation.

References: 1. P. Kumar, P. Devi, R. Jain, S. M. Shivaprasad, R. K. Sinha, G. Zhou, R. Nötzel, Nature Communications Chemistry 2 (2019) 4. 2. P. Devi, A. Thakur, D. Gosh, Senthil K, SM Shivaprasad, RK Sinha and P. Kumar International Journal of Hydrogen Energy (InPress 2019) 3. A. Thakur, P. Devi, S. Saini, R. Jain, R.K. Sinha, and P. Kumar, ACS Sustainable Chemistry & Engineering 7 (2019) 505 4. P. E. D. S. Rodriguez, V. C. Nash, P. Aseev, V. J. Gómez, P. Kumar, and R. Nötzel, Electrochemistry Communications 60 (2015) 158.

Mr Satish PatilImage Delegate ID Theme Details


Research


Organisation : Shivaji University, Kolhapur

Designation : DST-INSPIRE Fellow

Low cost, earth abundant precursor source Cu2ZnSnS4 (CZTS) films at various hydrothermal reaction time were successfully synthesized via facile one step hydrothermal route. As deposited CZTS films were analyzed for its optoelectronic and electrochemical properties to investigate the effect of hydrothermal reaction time on growth and photovoltaic performance of CZTS photoelectrode. The results showed that, hydrothermal synthesis promoted to high absorption (104 cm-1) of CZTS film with decrease in optical band gap energy from 1.52 eV to 1.41 eV. Improved crystallinity with pure phase kesterite crystal structure was observed with increment in deposition time. Raman analysis illustrates that, peak present at 331 cm?1 proved the A1 mode of vibration for pure kesterite CZTS crystal structure. Morphological analysis reveals that, formation of compact and well grown nanospheres at deposition time 6 h. Compositional analysis illustrates, stoichiometric CZTS film formation with desired valence state of Cu+, Zn2+, Sn4+ and S2- elements. Current density-voltage measurement of electrode configuration, FTO/CZTS/(0.3M Eu3+/Eu2+)/Graphite illustrates that, highest photocurrent of 2.60 mA/cm2 and open circuit voltage 754 mV observed for CZTS4 sample deposited at 6 h with best photoconversion efficiency (?) 3.5 % under illumination of 30 mW/cm2 light intensity. Electron impedance spectroscopy (EIS) showed that, generation of lower charge transport resistance (Rct) with increase in deposition time and well supports to the output photovoltaic performance CZTS thin films. References: 1. Zhou,Y. L.; Zhou, Zhou, W. H.; Li, M.; Du, Y. F.; Wu, S. X.; J. Phys. Chem. C 2011, 115, 19632–19639 2. Liu, F.; Li, Y.; Zhang, K.; Wang, B.; Yan, C.; Lai, Y.; Zhang, Z.; Li J.; Liu Y., Solar Energy Materials & Solar Cells 2010, 94, 2431–2434 3. Arul, N. S.; Yun, D. Y.; Lee, D. U.; Kim, T. W., Nanoscale 2013, 5, 11940 4. Gupta, S.; Whittles, T. J.; Batra Y.; Satsangi, V.; Krishnamurthy, S.; Dhanak, V. R.; Mehta, B. R., Sol. Ener. Mater. Sol.Cells 2016,157, 820–830

Mr Arpan TEWARYImage Delegate ID Theme Details


Research


Organisation : Central University of JharkhandDesignation : Student

Bismuth Telluride (Bi2Te3) is a well-known thermoelectric material both as thermoelectric powergenerator as well as Peltier cooler utilizing the principle of Seebeck effect and Peltier effectrespectively. In the present work, we report the effect of sintering temperature on Bi2Te3nano-crystalline powder synthesized using a high energy planetary ball mill. The ball-milling of thematerial was carried out at 500 RPM for 30 hours. The phase formation in the alloyed material wasconfirmed using X-Ray Diffraction measurements. The ball milled powder was then equally divided intotwo parts and sintered in vacuum of the order of 10-4 torr at two different temperatures, 723 K and823 K. The effect of sintering temperature on the thermoelectric response of Bi2Te3 material hasbeen measured in the temperature range of 300-573 K. In the sintered sample we could achieve themaximum ZT values of 0.8 and 0.75 at temperature of 150°C were recorded for the samples sintered at723 K and 823 K, respectively. The higher ZT value in sample sintered at 723 K is attributed to thehigher power factor value. The results suggest 723K to be suitable sintering temperature for Bi2Te3.

Mr LAXMAN MANI KANTA PUPPALAImage Delegate ID Theme Details


Research

Category : Energy EngineeringOrganisation :

INTERNATIONAL ADVANCED RESEARCH CENTER FOR

POWDER METALLURGY AND NEW MATERIALS (ARCI),

CHENNAIDesignation : PROJECT

SCIENTIST - B

Lithium ion batteries (LIBs) are the most promising energy storage systems, powering portableelectronics to electric vehicles. However, the limited resources of lithium in the earth crust canshoot up the cost of large scale applications. Sodium ion batteries (SIBs) have been identified as apotential alternative to LIBs for large scale grid energy storage because of abundance of sodiumresources, which is 2% of sea water1. Sodium (Na) is the second lightest alkali metal next tolithium and can deliver a high specific capacity of ~1167 mAh/g. In addition, aluminum (Al), whichdoes not form alloy with Na, can be used as current collector at the negative electrode side ofSIBs. The use of Al can further reduce the cost as well as improve the gravimetric energy density2.In spite of extensive research going on worldwide, the commercialization of SIBs is still far awayand it requires development of suitable electrode materials of high energy density and long cyclelife. Among various choices of cathode material, polyanionic materials with NASICON (Sodium ionSuper-Ionic CONductive) framework are structurally and thermally stable, which allows the3-dimensional diffusion of Na-ions into the structure3. In this regard, sodium vanadium phosphate(NVP) and its derivatives has been synthesized indigenously and tested in a half cell and symmetricfull cell modes. The NVP cathode material has shown a high specific capacity (110 mAh/g at 0.1Crate) with cell level voltage of ~3.4 V vs Na/Na+ and long cycle life (1400 cycles) in case ofsymmetric cell. The choice for anode materials for SIBs has been limited to hard carbon (HC) andsodium titanate (NTO). The non-carbonaceous anode, NTO is the most promising anode material,exhibiting an ultra-low Na+ ion intercalation voltage (~0.3 V vs Na/Na+) with a theoretical specificcapacity of 177 mAh g-1 (2 moles of Na+ ion)4. However, NTO suffers from poor cycle life due to itsinherent low electronic conductivity. Ex-situ carbon coated NTO has been synthesized indigenouslyand studied in half cell level. Carbon coated NTO has shown better electrochemical performancecompared to pristine NTO, where it showed high initial reversible capacity of 178 mAh/g at 0.1C rateup to 10 cycles. Demonstration of a full cell (pouch cell) using these electrode material is underprogress.

Mr Mohit SinglaImage Delegate ID Theme Details


Research


Organisation : Punjab Agricultural University

Designation : Ph.D. Student

Artificial roughness in form of rib is most effective method of improving the thermal performance ofsolar air heaters. In present work, thermo-hydraulic performance of evacuated tube solar air heaterroughened artificially with circular rib was evaluated using Computational Fluid Dynamics (CFD). Theinfluence of roughness geometry parameters i.e. relative roughness pitch (P/e) of 12 and relativeroughness height (e/Dh) of 0.057 on Nusselt number and friction factor was studied. Reynolds numberconsidered for investigation was varied from 2500 to 8000. Six different turbulence models have beenused for the analysis and RNG k-? with enhanced wall treatment turbulence model was found to be moreprecise in predicting the Nusselt number. It was found that performance of roughened evacuated tubesolar air heater is better than the performance of smooth evacuated tube. Nusselt number augmentswith the increase in Reynolds number while friction factor shows an opposite trend with increase inReynolds number. Maximum enhancement ratio of Nusselt number and friction factor was 2.14 and 1.54respectively, obtained at Reynolds number of 8000. The value of thermo-hydraulic performanceparameter for circular rib roughened evacuated tube solar air heater varied between 1.09 - 1.15 overthe entire range of Reynolds number.

Dr Usha SharmaImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : CSIR-Central Building Research Institute,

RoorkeeDesignation : Research

Associate

Uses of various types of silica nanoparticles (SNPs) have resultant in significant variation in theengineering properties of the concrete and thus, creating a lot of confusion amongst the concretetechnologist about the optimum dosages to be used in concrete mixes. Morphology and physical form ofSNPs are important parameters of SNPs before using them in the cementitious matrix. Therefore, tounderstand the effect of size and physical form of SNPs on its reactivity, three different types ofSNPs i.e. Elk microsilica (100-300 nm), colloidal SNPs (8-15 nm) and powder SNPs (20-40 nm) wereused for the present study. The early age reactivity of SNPs was monitored by synthesizing calciumsilicate hydrate (C-S-H) in the laboratory using lime/silica ratio 1:1.5 and the synthesized C-S-Hwas characterized with different techniques such as FTIR, NMR, XRD and FESEM. These results revealedthat in the presence of the colloidal and the powder SNPs, the structure of C-S-H gel was moreordered as the Q2 and Q3 peaks were intense. However, with microsilica, only Q4 peak whichrepresents unreacted silica was present showing the slower reactivity of microsilica. Thesenanoparticles were incorporated into cement mortar for evaluating compressive strength, gel/spaceratio, portlandite (CH) quantification, C–S–H quantification and chloride diffusion.Approximately, 27% and 37% enhancement in compressive strength was observed using colloidal andpowdered-SNPs, respectively, whereas the same was up to 19 % only when silica fume was used.Gel/space ratio was also determined on the basis of the degree of hydration of cement mortar and itincreases linearly with the compressive strength. Furthermore, DTG results revealed that limeconsumption capacity of powdered-NS is significantly higher than colloidal-SNPs, which results inthe formation of additional calcium-silicate-hydrate (C–S–H).

Dr TARIQUE AHMADImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : Aligarh

Muslim University, AligarhDesignation : Assistant

Professor

Purification of surface water for potable supplies typically involves the process of coagulation,flocculation, sedimentation, filtration and finally disinfection before feeding into distributionsystem. Large volume of sludge or waste is generated during the coagulation-flocculation processwhich is subsequently removed from the liquid phase in the sedimentation/filtration units. Disposalof sludge produced at water treatment plants require careful consideration for managing it, in anenvironmentally acceptable and sustainable manner. Several sludge disposal alternatives have beenidentified and investigated globally including various reuse options for safe and sustainabledisposal. In the present study, the sludge produced at the optimum alum dose required to treat theriver Yamuna water was acidified with 2.5 N sulphuric acids to regenerate the alum from theinsoluble aluminium hydroxide precipitate. The regenerated alum was reused with 1 % fresh alum totreat the surface water samples collected from river Yamuna. The performance of this combinedcoagulant was evaluated for turbidity removal by conducting batch experiments at low to high pHconditions and for variable dosage in a jar test apparatus. Results of the batch experiments carriedat variable dosage and pH conditions showed the feasibility of reusing regenerated alum from watertreatment sludge. An optimal coagulant dose of 8 ml/L efficiently removed the turbidity at neutraland higher pH conditions. Apart from turbidity other impurities like total dissolved solids,alkalinity, BOD, COD and iron were also found to be effectively removed from the raw water. Thequality of treated water met the prescribed standards for most of the quality parameters. Hence,regenerated alum has the potential to partially substitute the conventional coagulant at watertreatment plants.

Dr M Rehan SadiqueImage Delegate ID Theme Details


Research


Muslim UniversityDesignation : ASSISTANT

PROFESSOR

Urbanization of the world population is expected to reach 60% in 2030. Demand of expansion of oldcities and development of modern smart cities had forced engineers and planners to evaluate theunderground space utilization. The recent disaster in East-West Metro tunnel in Bowbazar, Kolkatta,India has again highlighted the complications involved in the tunneling through soft groundconditions. During tunneling process, ground settlement may be instantaneous, time dependent orinduced depending upon the in situ stress and stress redistribution mechanism. The ground settlementand volume loss may affect the stability of substructure and super structure above the tunnel andits vicinity. These settlements depend on several factors like soil properties, site geology andconfinement conditions. In the present study, a finite element analysis of underground tunnels inalluvial soil has been performed. Mohr-Coulomb failure criterion has been adopted for materialcharacterization of soil. However, the constitutive model for the concrete liner has been keptlinear elastic for simplification of the problem. Different opening shape of the tunnel has beenanalyzed under different overburden conditions. Ground settlement in all the conditions has beenobserved. Tunnels with circular opening has been found to be most safe shape, in term of groundsettlement. Further, different type of soil conditions has also been analyzed.

Mr Akash AgarwalImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : Jiet


The rising population and unplanned urbanization with the changing lifestyle have resulted in thecontinuous volume and composition of the solid waste in India. The amount of waste generated isabout 62 million tons each year as is expected to grow on an average of 4% each year. Also theamounts of the MSW waste will be increasing tremendously as the country thrive to becomeindustrialized nation by 2020. Since the composition of the waste generated in India does not offerslarger calorific value and the decomposition of the untreated waste at the dumping sites contributesto the greenhouse gases responsible for global warming. The lacking technologies, public interestand unavailability of suitable facilities required treating and dispose the solid waste is causingthe piling of solid waste in large metropolitan cities in India. To prevent the degradation ofenvironment and public health the infrastructure as well as the delivery mechanism for the solidwaste management as well as for the waste management system should be planned and implemented in theframework of the city development plan. Keen urban communities and Swachh Bharat Mission have made adomain for all the more however in no way, shape or form sufficient spotlight on the issue. Thispaper focuses on the difficulties and the likely solutions which could be implemented in the currentscenario as the solid waste rules are being discussed very well in public domain but themetropolitan cities have not come up with the integrated plan to tackle but have exacerbate it.

Ms Payal BakshiImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : CSIR-AMPRI,

BhopalDesignation : PhD scholar

Gypsum waste is obtained from flue gas desulphurization (FGD) process to avoid industrial emission of SO2 from coal power plants. In this study, physico-chemical characterization of waste gypsum obtained from National Thermal Power Corporation (NTPC), Rihandnagar, U. P., India is done by determining its moisture content, particle size analysis, specific gravity, density, pH, electrical conductivity, XRD, FTIR, SEM and FESEM-EDS. LDPE as binder and FGD gypsum as filler were mixed and samples were prepared by injection molding. The scope of making composites using LDPE is explored. Mechanical characterization of FGD-LDPE composites of various ratios (pure LDPE, 10%, 30%, 50% and 70% FGD) is done. Prepared composites were also analyzed for water absorption and density. It is observed that the density of composites is increasing with increase in filler percentage up to 50% then the density is reduced at 70% FGD. The LDPE acted as waterproofing for gypsum waste. Flexural strength of composites is increasing with percentage of filler up to 50% FGD. Tensile strength of composites is decreasing with the increase in percentage of filler up to 30% FGD. At 50% FGD the tensile strength increases slightly and again decreases at 70% FGD. The impact strength of composites is decreasing with increase in percentage of filler and is highest at 10% FGD. SEM shows the agglomeration of particles is reducing on heating at higher temperatures. Also the crystals vary in size and shape, textures and aggregates of FGD gypsum. Based on our preliminary research work, it is concluded that composite with glossy finish may be produced, which may have potential to be used as architectural interiors in building and transportation system. Detailed experiments have to be carried out following suitable casting/ fabrication techniques with varying waste gypsum quantity with different polymeric/ fibers system followed by its complete characterization.

Ms Jagriti SahuImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : Pt.

Ravishankar Shukla University raipur


The green buildings with ground source heat pump system concept which includes the renewable sources used for the construction. It reduces the cost and pay back within 10 years. The systems used are solar photovoltaic, solar distillation, solar water heater, solar cooker, geothermal heat pump etc., this sytems require less maintenance and high savings. This system concept is very much useful in keeping the environment clean which on a certain view even increases the life period of building. The choice of products used to build, renovate and operate structures has a significant impact on the environment. Wood products have less embodied energy, are responsible for lower air and water pollution, and have a lighter carbon footprint than other commonly used building materials. A home which can function using an optimum amount of energy, consume less water, conserve natural resources, generate less waste and create spaces for healthy and comfortable living, as compared to conventional buildings, is a green buildings with ground source heat pump system . Conventional methods of building use tremendous quantities of material, many of them non-renewable and toxic, and pay little attention to the impact the building has on the environment. This system, not only reduce these impacts but are also healthier and consume less energy saving money in the long run. When a number of green buildings are located in proximity, they would create a green zone, providing much healthier environment and minimize heat-island effect. The ultimate aim will then be to create many such areas, which would help the towns and cities and therefore the nation in reducing total energy requirement and also the overall global carbon footprint. The ground below the parking area, roads, garden etc. can be utilized for air conditioning in homes.

Mr Siddhartha PaulImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : Indian Institute of Technology

GuwahatiDesignation : Junior

Research Fellow

Demands for sustainable and eco-friendly ways of managing the menace of unwanted weeds are gearingup in the rural and semi-urban environment. Such weeds are noxious and are malign for our ecosystemand farmland as well. A sustainable cost is incurred by the farmers and/or agriculturists fortackling and weeding out such terrestrial weeds. Therefore, such biomass ends up as an unwantedwaste in our biosphere. Composting of such weeds could be a cost-effective alternative to convertthis unwanted biomass into value-added product and can provide the farmers with a source of income.However, the transformation of such waste into compost has a catch, wherein the phytotoxicallelochemicals present in the weeds are a hindrance in obtaining benign compost. The present studyattempts to employ 550L rotary drum composter for mitigating these malign allelochemicals in 20days. Cow-dung was used as inoculum and saw-dust as bulking agent, which were homogeneously mixedwith chopped pieces (1 - 2 cm) of Mikania micrantha kunth (a noxious terrestrial weed) followed byfeeding in the rotary drum composter. The composter was rotated once daily for better aeration andmixing. Samples were collected every two days in triplicates for various physicochemical analysis.In order to investigate the toxicity of the obtained compost, germination test with mung beans wasconducted at dilutions of 0%, 25%, 50%, 75% and 100% (v/v) under controlled temperature and lightingfollowing by darkness phases. Furthermore, advanced instruments such as GC-MS and FT-IR wereemployed to estimate the extent of attenuation in allelochemical content in the compost samples.Such investigations are truly pivotal in order to prescribe the user with benign product, which isnon-phytotoxic and is free from any toxic chemicals.

Mr Mayank MayankImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : NIT Jalandhar

Designation : M.Tech (Student)

EFFECT ON THE COMPRESSIVE STRENGTH OF CONCRETE WITH PARTIAL REPLACEMENT OF CEMENT WITH COCONUT FIBRES

1Mayank*,2Vaibhav Chaturvedi,3Shubam Gupta,4 Parampreet Kaur,5Gemini Durgapal, 1235Department of Civil Engineering, NIT Jalandhar, Punjab, India-144011 4Department of Civil Engineering, SBSSTC Ferozepur, Punjab,India Corresponding Author - 1 [email protected]

ABSTRACT Fibres which are eco friendly, pollution free and do not adverse impact on the environment and its constituents are called natural fibres. However, much emphasis has not been given, to the utilization and usage of these fibres.On the contrary,when these natural fibres are burnt as waste,it causes pollution and impacts on environment unfavorably.If these material fibres are used in construction materials,it could save the bio-reserves.Coconut fibre (C.F) has superior physical and chemical properties, this is because,it is resistant to thermal conductivity,high toughness,ductility,durability and is renewable and is cheap. Also it is capable of taking strain, four times more, than other fibres. Hence coconut fibre can be a better alternative as construction materials.The objective of this investigation is to improve the compressive strength property of concrete, using coconut fibre.In this study the behavior of specimen will respect to compression strength and cracking of concrete, has been investigated. Hence in this experimental study, the behavior of coconut fibre on the compressive strength of concrete was analyzed by partially replacing the cement with CF (2%, 3.5%, 5%).The cubes are tested after 3,7 and 28 days of curing. It was observed in this experimental study that with partial replacement of 2% CF with cement ,the compressive strength is increased up-to 18.48% after 28 days curing compared to conventional concrete of M30 grade. References- D.M Parbhane, S.B Shinde[2014] “Strength properties of coir fiber concrete”IJCIET,volume5,Issue 2,Feb(2014),pp-20-24. Shaikh Mohd Shadab Mohd Shafi,Siddiqui Masood Mouzzam,Hamza Sayyed Hasham Ali,Shaikh Shamsuddoha Mohd Umar[2015] “Effect of coconut fiber in concrete and to improve the workability by incorporating an admixture

Mr SRI PRANAP KImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : RATHINAM

SCHOOL OF ARCHITECTUREDesignation : ASSISTANT

PROFESSOR

Validating the performance of Hair Fibre Reinforced Concrete Beam (HFRCB) under monotonic loading Sri Pranap. K1* Department of Architecture, Rathinam School of Architecture, Coimbatore-641 019, India.

ABSTRACT Objectives: This research work tries to recommend the right use of disposed human hair. Human hair is abundance and time taking degradable fibre obtainable at very low cost and also carries the permissible tensile load. The scope of the work is to examine the performance of hair fibre reinforced concrete beams under monotonic loading. Methods/Analysis: The investigation also validates the strength and performance of the hair fibre reinforced concrete beams by match up with conventional beams and steel fibre reinforced concrete beams. This work aims at the confident use of hair fibres easily and practically in the construction industry, to be evidence for enhanced properties of concrete. The one such evidence is being discussed in the paper by taking human hair fibres cleaned with acetone. The human hair fibres are added 3% by weight of cement of all the sizes in concrete as strengthening material. Findings: The properties akin to compressive strength, split tensile strength, flexural strength, energy absorption capacity, ductility factor and stiffness of the beams are assessed and hair fibre reinforced concrete is found to be on the upbeat side. Application/Improvements: Micro crack formations in concrete are reduced by hair fibres, comparing to conventional concrete, conventional beam and cost-effective to steel fibre reinforced concrete.

Mr Amaanuddin AzadImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : CSIR-NEERI,

NagpurDesignation : Research

Scholor

Empirical development needs to address the environmental protection throughout the world. Theconstruction and structural industry include the huge amount of raw material that are responsiblefor high energy consumption and environmental issues. The Life cycle assessment of the material andprocess were done for analyzing the environmental effect and determine the energy efficientprocesses. The international standards the performance of life cycle assessment which includes thematerial production, construction phase, use and demolition of structural material are computeembodied energy, carbon dioxide equivalents with representation of consumption of resource, andemission released. The study of life cycle assessment analysis of structural material analysedaccording to the standard phase of life cycle assessment is to determine goal definition andscoping, inventory analysis, impact analysis, & improvement analysis. Beside this, analysis provideus data related to potential of environmental impacts like Global Warming potential, Ozone Depletionpotential, Human Toxicity, Particulate Matter, Acidification Potential, Eutrophication etc. Thecomparison of data helps us design high quality with Eco-friendly structural material. The analysisis based on comparative estimation of carbon footprint for proposed green material over conventionalstructural materials.

Mr Avishek ChatterjeeImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : Jadavpur

University Designation : Research

Scholar

Enhancement of structural properties and true self-healing by genetically-enriched spore forming Bacillus sp.

Avishek Chatterjee 1*, Brajadulal Chattopadhyay 2, Saroj Mandal 3 1Post-Graduate Student, Department of Physics, Jadavpur University, Kolkata-700032, India, E-mail: [email protected] 2 Professor, Department of Physics, Jadavpur University,Kolkata-700032,India, E-mail: [email protected] 3 Professor, Department of Civil Engineering, Jadavpur University,Kolkata-700032, India,E-mail: [email protected] *Communicating Author, E-Mail: [email protected]

Abstract: To reduce greenhouse gaseous emissions, various efforts are being studied to develop environmentally friendly construction materials. Fly ash is a coal combustion by-product that leads to many environmental problems like ground water contamination, spills, heavy metal contamination etc.. The release of considerable amount CO2 by cement industries and large quantity of fly ash by thermal power plants are both undesirable for environment. A geopolymer material was developed by incorporating genetically-transformed Bacillus subtilis bacterium (105 cells/ml) to an alkali- activator-treated 100% Fly ash to minimize environmental pollution. This paper discusses the mechanical strength, durability and microstructural properties of transformed Bacillus subtilis bacterium incorporated fly ash based geopolymer and self healing. For the preparation of samples, the Fly ash and bacteria cells containing activator fluid was mixed properly and the mixture was heat cured for 45 minutes before casting. After 24 h of casting, all the specimens were removed from moulds and cured at ambient temperature for several days until testing followed by generation of artificial cracks by applying partial breaking load (50%). Increase of ultrasonic pulse velocity and compressive strength, augmentation of sulphate resistance, decrease of chloride permeability and water absorption capacity revealed that there were overall improvement of mechanical properties and durability of the bacteria-incorporated mortar samples compared to the control (without bacteria incorporation) mortar samples. This cost effective and eco-friendly self-bioremediation phenomenon observed in geopolymer mortar may add a new dimension in self-healing construction technology in near future.

Dr Ajmal HussainImage Delegate ID Theme Details


Research


Muslim UniversityDesignation : Assistant

Professor

Water hammer is a pressure surge or wave caused when a fluid in motion is forced to stop or change direction suddenly (momentum change). A water hammer commonly occurs when a valve closes suddenly at an end of a pipeline system, and a pressure wave propagates in the pipe. It is also called hydraulic transients. Hydraulic transients occur as a direct result of rapid variations of flow field in pressurized systems. The change in velocity from valve closures or pump operations causes pressure surges that are propagated away from the source throughout the pipeline. The elasticity of the pipe boundaries and the compressibility of the fluid prevent these sudden changes in pressure from taking place instantaneously throughout the fluid. The associated pressure changes during a transient period are often very large and occur very rapidly (within a few seconds). If the maximum pressures exceed the bar ratings (mechanical strength) of the piping material, different types of failure such as pipe bursts can occur. Similarly, if the minimum pressure drops below the vapour pressure of the fluid, cavitations can occur and can be detrimental to the pipeline systems. Hydraulic transient events in water distribution system can cause significant damage, disruption, and expense. Hydraulic transients in closed conduits have been a subject of theoretical and practical research for more than a century. A variety of commercial software is available for simulating hydraulic transients and can be used for the design of sophisticated pipeline networks and for research studies. The purpose of present study is to model and simulate hydraulic transients in a pipe line network system using Bentley HAMMER v8i. Various scenarios have been simulated using different combinations. The simulation results show that the transient pressures in the pipeline exceeded the bar rating of the pipe where the bursts or cavitations may occur for the simulated scenario but transient pressures were reduced to safe limit after providing water hammer protection devices.

Keywords: Pipe network, Hydraulic transient, Water hammer

Dr R SIVA CHIDAMBARAMImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : CSIR Central Building Research Institute

Roorkee Designation : Scientist

The article presents the experimental behavior of seismic resistant precast connections underreverse cyclic loading. Precast constructions are being carried out using different factory madeelements assembled at the construction site. Various structural components such as wall panels,slabs, columns, foundations and shear wall are independently made and connected together with eachother using diverse techniques. There are three commonly used connection technique namely wet, dryand wet-dry joint principles in precast elemental connections. The reduced time limit, betterworkmanship and superior quality control increases the use of precast system across the world.However, failures of precast structures during natural and manmade disasters show the vulnerabilityof the elemental connections and associated problems. In particular the precast framed structurefails to behave like monolithic construction during earthquake. Thus, the precast connections apotential risk zone during severe loading. This paper presents an experimental behavior ofinnovative seismic resistant precast column to foundation connection subjected to cyclic loading.The performance of the proposed novel connection technique under reverse cyclic loading has beencritically analyzed using various parameters such as connections mechanism, stiffness, energydissipation and damage tolerance capacity.

Mr Ashish KulkarniImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : MAHATMA EDUCATION SOCIETY'S , PILLAI HOC COLLEGE OF

ENGINEERING AND TECHNOLOGY, RASAYANI


In Mumbai city Railway is the most important public transport mode on which the number of people depend for most part and the number of users using this mode is huge. In news, we hear about different accident cases related to it, along with different reasons for happen so. One of these reasons at that time is what causes accidents is gap between edge of station platform and the footboard. Actually, as per IS code provisions, providing this gap is important. But due to some construction defects, and some other reasons this gap is more than standard size required. So, because of this extra gap some passengers fell down as they go up and down in train during regular as well as rush hours transactions. Many solutions have already been explored in other countries on this issue. But it is not possible for some reasons to use them here in India. Therefore, the government of India has found a solution to increase the height of existing platform in accordance with IS code standards to help to reduce this extra gap properly. This Discovered solution of government of India is very effective. But according to my study I have found some drawbacks in this remedy, which are delaying the implementation of this solution as well as having difficulty to completing work in due time. These drawbacks are, the separate and more time-consuming process so that the daily transactions are not be interrupted as well as modifications and changes required for the existing structures. There are a few important points I focus on when looking for this solution. The point are, human tendency of the people in our country, Simple and as well as less time-consuming for adoption, the existing structures does not require any modifications and changes, Huge number of people are using this mode of transport at the same time. So, the solution found by me helps to overcome these drawbacks and useful for minimizing accidents. Keywords: Footboard, Accidents, Platform, Train, Extra Gap.

Mr Aahaan NaikImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : Amity

University, ChhattisgarhDesignation : Student

Abstract: 3D printing technology is increasingly gaining public interest. This technology isrevolutionizing the way people are working and living now. By using this technology we can turn ourideas into physical object. Here a 3 dimensional object is created by lying down the successivelayers of a material. 3DP has been increasingly used in different areas, including medical,automotive, aerospace, etc. This automated and accelerated process is also promising for civilstructures, including building and bridges, which require extensive labor. If successful, it isexpected that 3D structural printing can significantly reduce the construction time and cost. Itsaves wastage of material. This papers aims to explore it's basic advantages and the applicabilityof 3DP for civil structures as well as in other fields also. Finally, future directions for 3DP incivil structures and other areas are discussed.

Mr Venkata Naveen KothapalliImage Delegate ID Theme Details


Research

Category : civil EngineeringOrganisation : IIT RoorkeeDesignation : Research

Scholar

This article presents an experimental study on a local retrofitting scheme, where the damaged orruptured rebars in the column members of a Reinforced Concrete (RC) frame were re-established byconnecting them using in-house made rebar coupling sleeve. Rebar coupling sleeves with innovativeconfining technique had been adopted in retrofitting a severely damaged RC portal frame. Asingle-story RC frame damaged under the collective application of constant vertical load and lateraldisplacement was tested and then repaired using the above mentioned innovative technique. Theretrofitted RC frame was tested under identical conditions as that of the original frame undercyclic loading and the parameters like hysteresis behavior is compared with the original frame alongwith empirical parameters like energy dissipation, ductility, strength and stiffness degradation,and viscous damping. The structural performance of the RC frame gets restored up to its primitivelevel with an increase in its lateral load-carrying capacity, which authenticates the efficiency ofthe proposed retrofitting technique.

Ms GOLDY SHAHImage Delegate ID Theme Details


Research

Category : Chemical Engineering

Organisation : IIT DELHIDesignation : PhD Research

Scholar

Multi-fold increase in energy demand worldwide has led to a situation where the quest for alternateenergy sources has become unavoidable. Besides many other problems, the world is challenged byglobal warming, and the target is to reduce greenhouse gas (GHG) emissions. Moreover, biogas is abio-renewable energy resource which has the potential to serve as a possible replacement for fossilfuels especially natural gas. Interestingly, the biogas application at commercial scale may help ingetting rid of biomass waste and reducing GHG emissions. However, compressed biogas (CBG) isconsidered to be a potential alternative to compressed natural gas (CNG) because of itscompositional similarity to CNG. Pressure swing adsorption-based biogas upgradation technology hasthe remarkable potential to produce bio-CNG as an alternative for natural gas. Over the decades, PSAperformance has been described by different mathematical models, but there is limited work done inthe field of process simulation where adsorbent models can be incorporated with other unitoperations using a commercially available simulator. A major issue faced in the majority of theupgradation plant is that an off-gas stream with a significant methane content is produced andreleased directly into the atmosphere, which requires to be treated further to avoid emission intothe environment. Therefore, this work aims to evaluate different parameters and off-gas treatmentfor developing an efficient model for reducing methane loss. The mixture used as feed was 55-60% CH4and 35-40% CO2 with pressure swing between 5 bar in adsorption mode to 0.1 bar in blowdown.Microporous CMS prepared in work exhibited type 1 isotherm with a pore size of 2.03nm, the highsurface area of 700m2/g, high affinity to capture CO2. The highest methane purity of 93.5% withrecovery higher than 86% was obtained by PSA operated at 60s of adsorption and blowdown time.

Mr Mata Mani TripathiImage Delegate ID Theme Details


Research


Organisation : Rajiv Gandhi institute of Petroleum and

technologyDesignation : MTech student

Inspired by the use of low quality feed-stock neem oil for biodiesel production, non-catalytic route was investigated. However non-catalytic esterification of neem oil for biodiesel production requires severe condition such as high methanol to oil ratio, high temperature. Therefore, in this work the role of deep eutectic solvents (DESs) was used to achieve facilitate biodiesel production at less severe condition. The DESs were synthesized by mixing hydrogen bond donor and hydrogen bond acceptor in fixed molar ratio having melting point below than either of precursor. Process parameters such as methanol to oil ratio, time, temperature and DESs dosage were investigated to optimize the production of biodiesel from neem oil. The results show that esterification of neem oil to biodiesel is completed within 90 minutes and the biodiesel conversion increases with increasing temperature. In addition, increasing the DESs dosage enhances the biodiesel production.

Mr sathishkumar vImage Delegate ID Theme Details


Research


Organisation : Paavai Institutions

Designation : Chemical Engineering

A chemical spill is a situation in which a chemical is accidentally released. However,spills of toxic chemicals represent a more serious problem. The main objective is to design thenanobot for the removal of chemical spill to ensure the safety of the environment and to check howit works by comparing its absorption capacity with the existing absorption methods for removing thechemical spill. The simulation of the robot will be presented through robot simulation software,where the tracking is done through embedded programming, so as to configure its movement andrequirements through every cycle of change of state. A prototype of the nanobot is constructedthrough hardware with the help of robot-specific apparatus and with the same norms of a linefollower robot. In summary Nanobot would be useful technology used for removal of oil spill.

Mr Vignesh JImage Delegate ID Theme Details


Research


Organisation : PAAVAI Engineeering CollegeDesignation : Student

The current scenario states that more than 15% of air pollution is caused by the industrial emissions. Most probably, malodourness (VOCs) gases are released from the industries. The present study is to eliminate those harmful gases released from industries without any secondary pollutant using soil as the filter media for bio-filtration. In addition to this, for the better augmentation of the activity of nitrogenous bacteria, coffee seeds will be used. Further this ingenious idea promotes artificial photosynthesis where CO2 is converted into useful hydroxyl compounds. Comparison also made between the already available manure and the yield product. In summary, this project would be useful to degrade industrial air pollutant without any secondary pollutants in an eco-friendly manner.

Mr Neelanjan BhattacharjeeImage Delegate ID Theme Details


Research


Organisation : Calcutta University

Designation : Senior Research Fellow

The fast pyrolysis of Alternanthera philoxeroides and Ageratum Conyzoides were evaluated with afocus to study the chemical and physical characteristics of pyrolysis oils produced and to determinetheir practicability as a transportation fuel. Constant particle size of 0.212 (Alternantheraphiloxeroides) and 0.425 (Ageratum Conyzoides) mm were used during the entire experimental runs. Theeffect of different operating conditions like temperature [Alternanthera philoxeroides (350 – 550°C) and Ageratum Conyzoides (350 – 600 °C)], heating rates (25 – 100 °C min-1) and N2(sweeping gas) flow rates (0.1 – 0.5 L min-1) on the pyrolysis product yields, respectively. Themaximum pyrolysis oil (Alternanthera philoxeroides) of 41.26 wt.% was obtained at a temperature of500 °C under a constant heating rate and N2 gas flow rate of 50 °C min-1 and 0.3 Lmin-1.Similarly, the maximum pyrolysis oil (Ageratum Conyzoides) yield of 37.55 wt.% was achieved at atemperature of 525 °C under a constant heating rate and sweeping gas flow rate of 75 °C min-1 and0.2 L min-1. The characterization of the biomasses, pyrolysis oils and biochar were performed by theTGA, CHNSO analyser, FT–IR, GC–MS, SEM, XRD and BET techniques. The HHV value of theAlternanthera philoxeroides and Ageratum Conyzoides pyrolysis oils were 8.88 and 17.79 MJ kg-1andthere biochars were 20.41 and 22.93 MJkg-1, respectively. Presence of lower and higher hydrocarboncompounds in the pyrolysis oils (Alternanthera philoxeroides and Ageratum Conyzoides) makes them asuitable feedstock for the production of various chemicals. The biochars can be used for adsorptionpurposes, solid fuel or can be used in soil amendment properties due to its good surface area andhigh alkalinity as well as carbonaceous nature. The high gross calorific value of thepyrolysis-gases > 5MJ m-3 permits them to be utilized as an alternative gaseous energy source.

Mr Kishore KumarImage Delegate ID Theme Details


Research


Organisation : Paavai engineering college

Designation : Chemical engineering

Dye Sensitized Solar Cell (DSSC) was first discovered in 1991 by O'regan and Gratzel. This new type of solar cell was reported to have lower production cost with efficiency as high as 12% which is comparable to conventional silicon solar cell. Initially, it uses blackberry dye (anthocyanin l) as light sensitizer for the operation. However, DSSC with blackberry dyes (anthocyanins) are facing environment friendly issues. Regardless of the poor performance campared with ruthenium dye but it's cost wise high and purification process release the toxic content. Natural dyes which are easy to prepare, cheap and environmental friendly still appear to be an alternative as dye sensitizer. In this study, dye sensitized solar cells (DSSCs) were fabricated using anthocyanin source dyes extracted from several different fruits. Therefore, all of the natural dyes show light absorption properties which is important for a dye sensitizer. A DSSC is comprised of conductive substrate, nanoporous semiconductor TiO2 layer, dye sensitizer, electrolyte with redox couple and a counter electrode with catalyst.

Mr BISWANATH BISWASImage Delegate ID Theme Details


Research


Organisation : UNIVERSITY OF CALCUTTA

Designation : RESEARCH SCHOLAR

Bioethanol production from Water hyacinth using Saccharomyces cerevisiae Biswanath Biswas*, Asit Baran Biswas Department of Chemical Engineering; University of Calcutta, UCSTA; 92, A.P.C Road; Kolkata-700009; India Mobile: 7003296616 Email: [email protected]

Abstract: The countries like India are facing a crisis, mainly due to the import of crude petroleum oil from other countries. Water hyacinth look for alternative fuels biomass with no food value is of major interest and expected to be the main feedstock for the bioconversion process. WH (Eichhornia crassipes) consider one of the suitable lignocellulosic materials for fuel ethanol production due to easy high availability in a tropical country like India. Studies in our laboratory indicated that water hyacinth contains 20.5 % cellulose, 40.1 % hemicelluloses and 13.9 % lignin. Water hyacinth is thus lignocellulosic biomass as a good source of reducing sugars obtained to hydrolyse water hyacinth, which can be farther used for the production of ethanol. Microorganism’s yeasts tolerate a wide range of pH, ethanol, and temperature are widely used for production of bioethanol. Chemical pre-treatment of water hyacinth improves the yield of sugar and processing time. The best treatment method is steaming with high pressure (at 20lb/ inch2 pressure for 30 minutes), with a yield of 97.50 % sugar in the alkali treatment process. We have also developed ethanol and temperature resistant strain of a Saccharomyces cerevisiae AB810. The fermentation medium of the following composition glucose (obtained to hydrolyse water hyacinth), NaNO3, NaH2PO4, MgSO4.7H2O, KCl, yeast extract, peptone, paddy soak liquor, beef extract and micronutrient ZnSO4.7H2O, Fe2 (SO4)3. H2O, MnSO4.7H2O at pH5, which gives maximum production of ethanol (13.4% v/v) in 48 hours, which is ethanol yield efficiency 82.84% in the batch reactor.

Keywords: Water hyacinth, pretreatment, Saccharomyces cerevisiae, Bioethanol.

References: 1. Biswas, B.; Banik, A.K.; Biswas, A.B. Int. J. Biotech Trends Tech. 2015, 5, 11-16.

Mr Avinash RImage Delegate ID Theme Details


Research


Organisation : Paavai engineering college


Diabetes is a disease that occurs when your blood glucose, also called blood sugar, is too high.There is no cure for diabetes, but it can go into remission. People can manage it with medicationand lifestyle changes. Phyllanthus niruri is used in medicine for treatment of diabetes. Theobjective of this study was to investigate the antidiabetic potential of phyllanthus niruri. Thepresent study demonstrated that P. niruri may have potential application for treatment andmanagement of type 2 diabetes and also different components like alkaloids, terpenoides, lignins,polyphenols, tannins , sapnonins and coumarins are isolated and identified using thin layerchromatography ( TLC ).These findings indicate the antidiabetic usuage of Phyllanthus niruri insoxhelt extraction.

Mr Koushik GHoshImage Delegate ID Theme Details


Research


Organisation : University of Calcutta


Adsorptive removal of Crystal Violet and Malachite Green using Eucalyptus Leaf

Koushik Ghosh*, Sudip Kumar Das, Asit Baran Biswas

*Department of Chemical Engineering, University of Calcutta, 92 APC Road, Kolkata - 700009 Email: *[email protected]

Abstract: Dyes are used in large quantities in many industries, which generate colour content wastewater. Coloured wastes may contain chemicals which exhibit toxic effects to mammals; hence, these are needed to remove from the industrial wastewater. The adsorption methods show to recommend the best potential for overall treatment, and it could be expected to be promising for a wide range of compounds, than any of the other processes. The use of eucalyptus leaf (EUL) and its potentiality to remove basic dyes (crystal violet CV, and malachite green MG) from aqueous solutions were elucidated in this research work. The adsorbent was characterized with Fourier transform infrared spectrophotometer (FT-IR) and scanning electron microscope (SEM). Various physicochemical parameters were inspected in a batch-adsorption method.

More than 90% removal of CV and MG was possible at specified process parameters. Different kinetic models were applied to test the experimental data. The pseudo-second order exhibited the best fit for the kinetic studies, which indicates that adsorption of CV and MG is limited by chemisorptions process. The different isotherm models were tested using experimental data. The Redlich-Peterson model best describes the uptake of CV and MG dye, which implies that the adsorption of these basic dyes onto eucalyptus leaf is heterogeneous with multi-layers. It was found from different thermodynamic parameters that CV and MG dye adsorption was spontaneous and endothermic.

References:

Zhou, Y., Lu, J., Zhou, Y. & Liu, Y. Recent advances for dyes removal using novel adsorbents: A review. Environ. Pollut.252, 352–365 (2019).

Mr SUJASH PRADHANImage Delegate ID Theme Details


Research


Organisation : RAJABAZAR SCIENCE COLLEGE,

CALCUTTA UNIVERSITYDesignation : M.TECH

Pyrolysis of Biodegradable Municipal Waste Sujash Pradhan*, Puranjan Safui, Asit Baran Biswas Department of Chemical Engineering; University of Calcutta, UCSTA; 92, A.P.C Road; Kolkata-700009; India Mobile: 9547453461,7908312537 Email: [email protected]

Abstract : Rapid increase in urbanization and per capita income lead to a high rate of hazardous municipal solid waste generation. Pyrolysis is found to be the most inexpensive, simple and energy-efficient mode of upgrading/ value addition solid waste and preventing pollution. A semi-batch reactor was used for the pyrolysis of biodegradable waste biomass. A total of 10 kg biodegradable kitchen waste consisting mainly vegetable peel, paper, wood is collected and the samples were sun-dried for 7 days. The waste then dried in a hot air oven maintained at 100 ± 5 °C for 4 h to remove the excess moisture. Using a mixer grinder the samples were grinded and then sieved to four different particle size ranging from 1.19 – 1.21, 0.707 – 0.756, 0.518 – 0.553 and 0.210 – 0.218 mm. The proximate analysis of the waste bio-mass indicates the moisture content of 4.5 wt.% whereas volatile matter, ash and fixed carbon content was 73.2 wt. %, 21.06 wt.% and 1.24 wt.% respectively. The H/C and O/C molar ratio of the waste bio-mass was 1.64 and 0.91 respectively, therefore, had an HHV of 15.25 MJ Kg-1 which is similar to the HHV of raw food waste. The bio-mass had a surface area of 20.55 m2g-1. The highest bio-oil yield of 22.42 wt. % was achieved at a temperature, constant heating rate, N2 gas flow rate and particle size of 650°C, 5 °C min-1, 0.1 L min-1 and 0.210 – 0.218 mm respectively. The CHNS and O, FT-IR, 1H-NMR, GC-MS, XRD, SEM and BET is used for analyzing the feedstock and products.

Keywords: Municipal waste; Pyrolysis; Bio-oil; Bio-char; Kinetic Modelling.

Mr Mohd Belal HaiderImage Delegate ID Theme Details


Research


Organisation : Rajiv Gandhi Institute of Petroleum

TechnologyDesignation : student

Deep eutectic solvents (DESs) are formed by the hydrogen bond donor (HBD) and hydrogen bond acceptor(HBA). They can be tailored made depending on the choice of HBD and HBA. This open the vast application of the DESs to be used in the refinery. In this work, we present the application of DESs in the field of carbon capture(CC) and isopropanol(IPA) recovery from industrial waste water. For CC, three different methyltriphenylphosphonium bromide based deep eutectic solvents (DESs) were synthesized and their ability to capture CO2 was experimentally investigated. Ethylene glycol, diethylene glycol and glycerol were used as hydrogen bond donor for DESs synthesis. The CO2 uptake in DESs were measured using pressure drop method at different temperature and pressure. Critical properties of synthesized DESs were calculated using “Modified VFT” equation. Peng-Robinson equation of state was used to model the experimental vapor liquid equilibria data of CO2/DESs system. In addition, flue gas decarbonization process was simulated using predicted properties data and experimental VLE data. Sensivity analysis was employed to the DESs-based process to obtain the optimal parameters. In addition, heat integration was used to further lower down the energy requirement. For recovering isopropanol(IPA) from water five different hydrophobic DESs were synthesized using natural precursor such as menthol. The ternary liquid-liquid equilibrium between water-IPA-DESs were studied. The result shows that the the slope of tie line is positive which indicate that IPA can be recovered from the industrial waste water using synthesized hydrophobic DESs.

Mr Sudipta LetImage Delegate ID Theme Details


Research


Organisation : University of Calcutta


Hydrodynamic characteristics of binary solid-liquid fluidization system: ANN Modeling Sudipta Let*, Ranjan Kumar Basu and Sudip Kumar Das Department of Chemical Engineering University of Calcutta, 92 A.P.C. Road, Kolkata - 700009 *Corresponding author: Research Scholar; E-mail: [email protected] Abstract: Fluidization is a process where a granular material is converted from a static solid-like state to a dynamic fluid- like state. Fluidized beds are applied in industry due to their large contact area between phases, which enhances chemical reactions, heat transfer and mass transfer [Mandal et al. (2012)]. Experimental investigation of the fluidization behavior in unary and binary solid-liquid fluidized beds of non-spherical particles as solid phase and water as the liquid phase were done in different diameters perspex columns of two different diameter. Different average particle size from 3.057×10-3 m to 7.74×10-3 m was used to prepare the binary solid beds in a different weight ratio for fluidization. The pressure drop across the fluidized bed were measured by inclined manometers at different liquid velocities, measured by rotameter. The effect of different operating parameters, like particle size, sphericity, column diameter on minimum fluidization velocity had been investigated. For binary solid bed, minimum fluidization velocity (Umf) increases with increasing the fraction of smaller diameter particle due to particle drag force, which makes the larger particle fluidized in lower liquid velocity. It had also been observed that as the sphericity of the particle decreases, minimum fluidization velocity increases. The experimental values were compared with the correlations available in the literature, and an empirical correlation has been developed. Applicability of the artificial neural network modeling using Gradient descent and Levenberg-Marquardt algorithm has also been successfully tested.

References: 1. Mandal, D.; Vinjamur, M.; Sathiyamoorth D. Y., Hydrodynamics of beds of particles in the voids of coarse particles, Powder Technol. 2013, 235, 256–262.

Dr Suparna SahaImage Delegate ID Theme Details


Research


Organisation : Jadavpur University

Designation : Post Doctoral Fellow

Mitigation of Greenhouse effect: Selective and Economic Conversion of CO2 to fuels and key building block chemical Suparna Saha, Arundhati Sarkar, Kajari Kargpta* Chemical Engineering Department, Jadavpur University, Kolkata-32 E-mail address: [email protected] Abstract: In this era of rapid industrialization as well as combustion of fossil fuels (coal, natural gas, and oil) for energy and transportation, the billions metric tons of carbon dioxide (CO2), main contributor of greenhouse gas, that we release into the atmosphere and this CO2 is constantly being exchanged to balance the greenhouse effect. But as we overload our atmosphere with carbon dioxide, more and more heat is trapped and that believed to be the primary sources of the global warming. Thus, it’s a high time that we have to simply use all that wasted CO2 and turns it into something useful products. By adding electricity, water, variety of catalysts one can reduce CO2 to form more complex hydrocarbon fuels like methanol, ethanol, ethylene, methane etc. But the major challenges involved are the loweing of the energy requirement to convert the most stable carbon dioxide molecules and the product selectivity. To address this issue a new catalyst was prepared based on conducting polymer-graphene and Cobalt nanoparticles that electrochemically converted CO2 to ethanol and ethylene selectively. Use of polymer matrix helps to adsorb the CO2 whereas Graphene-Cobalt composite facilitate to produce most useful commercial products ethanol/ethylene in one step. Tuning of products could also be achieved by simple changing the constituent materials of catalyst. Further, the prepared catalyst was found to perform consistently for almost 4 hours/per day with no loss in efficiency at an overall efficiency ~51%. Complete suppression of the competing hydrogen evolution during electrolysis was also achieved using this catalyst. In addition, the long-term stability (~ 6 months) demonstrated by these cheap, and efficient catalysts is key to developing an industrially reliable electrolyzer system for ethanol/ethylene production. Hence, this achievement of CO2 conversion into carbon-based fuels (such as methanol, ethanol ethylene, etc.) could help to reduce our dependence on fossil fuels while simultaneously mitigating net CO2 emissions and obviously greenhouse effect. References: 1. S Gao; Y Lin; X Jiao; Y Sun; Q Luo; W Zhang; D Li; J Yang; Yi Xie, Nature Communication, 2016, S29, 68-71

2. F. Robert.; S. Benjamin.; R. Michael. Chem. Rev. 2018, 118, 4631?4701

Mr Manas DwivediImage Delegate ID Theme Details


Research


Organisation : Rajiv Gandhi institute of petroleum

technologyDesignation : student

Removal of pollutants from industrial wastewater has become one of the most important issuesrecently for the increase in industrial activities, especially for heavy metals and radionuclides.Since the big nuclear accident at Fukushima, Japan in 2011, a large number of radionuclides werereleased into water, soil and air, and the hazardous influence of radioactive wastewater has drawnmuch attention all over the world. Among radionuclides, 137Cs is considered the most abundant andhazardous due to diverse sources and relatively long half-life. Furthermore, it can be easilyincorporated into terrestrial and aquatic organisms because of its similar chemical characteristicswith potassium. Present Work reports removal of cesium ions from aqueous solution of high levelwaste using the Carboxylic-Acid based various hydrophobic deep eutectic solvents, which are greensolvents and formed from a eutectic mixture of hydrogen bond donor (HBD) and hydrogen bond acceptor(HBA). And maximum separation is observed when carboxylic-acid-based DES has ionic character. Thischarge transport properties resemble those of a protic ionic liquid.

Dr Ranjana Das MondalImage Delegate ID Theme Details


Research




Abstract Membrane reactor is a physical device that combines the function of reaction and separation in a same assembly, for synthesis and isolation of value added compounds from waste resources and removal of objectionable components from waste to get eco-friendly output. This work aims to present a case study to get value for waste, illustrating the technology involved in getting bioactive peptide from abandoned biomass and evaluation of functional properties. The biomass of interest is mango kernel which is abandoned in nature, hence, new aspects concerning the use of this waste for further exploitation on the production of food additives or supplements with high nutritional value may be of great importance [1]. ‘Amrapali’ the hybrid between ‘Neelam’ and ‘Dashehari’ varieties contain 2.5–3.0 times more ? carotene than other varieties [2] is chosen as waste biomass. Proximate analysis of mango kernel illustrates about 7.5 g/100g protein with several macro minerals required for vital functions of the body. The mango kernel after defatting was subjected to protein isolation followed by protein hydrolysis and subsequently the mango kernel hydrolysate was fractionated in membrane bioreactor to obtain desired fraction. The antioxidant properties (radical scavenging activity) of the desired fraction were assayed and obtained 9.2% scavenging with degree of hydrolysis 30%. Inverse co-relation of the degree of hydrolysis with radical scavenging activity was observed at higher range, which may be due to the formation of free amino acid residue which exhibited comparatively lower radical scavenging properties as compared to short peptides. From the results it may be concluded that, membrane reactor is broad based technological development which can be exploited in diverse domain for human benefits for producing nutritional supplement as well as to manage bio-waste.

Ms Preetha GangulyImage Delegate ID Theme Details


Research



Designation : Project Associate

The increase in population growth worldwide over the past few decades led the need to provide access to clear, clean and safe water to meet the human requirements. There is an emerging need for cost efficient technique for wastewater and water treatment in order to meet the worldwide demand and the methodical standards of water quality and at the same time increase the pollutant removal efficiency. Currently used remediation techniques have failed to meet the above mentioned factors without becoming price-prohibitive. New research have shown nanotechnology as best alternative to increase the accessibility to clean water by remediation of the contaminated waste water. The present research reports an economical, eco-friendly method to synthesize Titanium dioxide and iron oxide GO nanocomposites. The titanium dioxide (TiO2) is used as a photocatalyst for decontamination of waste water. Titanium dioxide (TiO2) has gained continuous interest because of its stability, less toxicity, efficiency and price effectiveness. Whereas the use of iron oxide GO nanocomposite as an adsorbent has led to new strategies for magnetic separation technologies for waste water treatment. TiO2-GO nanocomposite was prepared by thermal hydrolysis of graphene oxide with Anatase. The Magnetically separable graphene oxide/iron oxide were prepared by utilizing ferrous sulphate and ferric chloride along with NaOH. The morphological, optical and crystalline information’s of the synthesized TiO2-GO and iron oxide-GO nanocomposite were studied utilizing Fourier-transform infrared spectroscopy (FTIR) and TGA. Crystal Violet (CV) dye was utilized as a model for contaminates. The adsorption activity of Anatase-GO and Iron Oxide-GO were evaluated for the degradation of Crystal Violet dye in aqueous medium under UV radiation. The result showed that Anatase-GO exhibits higher photocatalytic efficiency in comparison to Iron Oxide-GO. Reference:- 1 Perera , D, S., Patel , B., Bonso ,J., Grunewald ,M., Ferraris,P,J., Kenneth J. ACS Applied Materials & Interfaces , 2011, 3, 11, 4512-4517 2 .Singh, V.K., .Patra , M.K., .Manoth , M .,Gowd , G.S., .Vadera, S.R ., Kumar, N. New Carbon Material.2009, 24, 147-152.

Ms Rwiddhi SarkhelImage Delegate ID Theme Details


Research




Synthesis and application of iron nanoparticles in wastewater treatment by removal of dye Rwiddhi Sarkhel, Preetha Ganguly, Papita Das*, Avijit Bhowal School of Advanced Studies in Industrial Pollution Control, Jadavpur University, Kolkata [email protected], [email protected], [email protected] Department of Chemical Engineering, Jadavpur University, Kolkata [email protected] *Corresponding author: Papita Das, School of Advanced Studies in Industrial Pollution Control, Jadavpur University, 188, Raja S. C. Mullick Road, Kolkata-700032, Email: [email protected]. Abstract: Wastewater treatment is a crucial, trending environmental concern presently. In this study, iron nanoparticles were synthesized using activated carbon from raw sugarcane bagasse and bagasse impregnated with ZnCl2. Physical and Chemical properties of the nanoparticles proved it to be iron nanoparticles. The synthesis of iron nanoparticles being a cost effective and ecofriendly treatment technique, is gaining importance nowadays. Synthesis of iron nanoparticles has been done to evaluate its efficacy in treating wastewater by the batch adsorption technique (dye removal). Sugarcane bagasse, collected from local markets near Jadavpur were washed, oven dried and then grinded into fine powders. The grinded form of sugarcane bagasse was used for pyrolysis, maintaining a temperature of 400-600°C for 1 hr. Then some of the prepared activated carbon was treated with ZnCl2. 0.2 g of the prepared activated carbon (raw and treated) was now further used for the synthesis of iron nanoparticles using ferric chloride and ferrous sulphate in 1:1 ratio, maintaining an anaerobic condition and finally magnetic iron particles were obtained after treating the mixture with KOH. The characteristics of the iron nanoparticles were evaluated using the following techniques like SEM, XRD, FTIR. Different parameters like adsorbent dose, pH, temperature, concentration of adsorbent was also assessed. Iron nanomaterials have been the potential adsorbents for current wastewater treatment because they can be easily separated via magnetic field from the metals, dyes and can be used in the purification of drinking. They are one of the best adsorbents for treating industrial effluent by saving the environment and humankind as it is cheaper and more efficient in purifying contaminated drinking water. Keywords: Sugarcane-bagasse, Activated-carbon, Iron-nanoparticles, Adsorption, Wastewater treatment. I am thankful to RUSA 2.0 for providing me the financial support in doing this project topic. References: 1.Zamani A; Poursattar A; Mousavi Z, Agricultural waste biomass-assisted nanostructures: Synthesis and application, Green Process Synth 2019, 8, 421–429. 2. Foster S; Estoque K; Voecks M; Rentz N; Greenlee L, Removal of Synthetic Azo Dye Using Bimetallic Nickel-Iron Nanoparticles, Journal of Nanomaterials 2019, 12, 605-617.

Mr SOUPTIK BHATTACHARYAImage Delegate ID Theme Details


Research



Designation : PhD (SRF)

The ability of poly ethylene glycol (PEG) to influence the pharmacokinetic properties of solid andliquid drugs is currently used worldwide for established and emerging drug delivery applications inbiopharmaceutics. The change in the pharmacokinetics of the drugs by being shielded to PEG resultsin prolonged blood circulation time and drug stability enhancement. This consequently increases theprobability that the drug reaches its target site of action before being recognized as foreign andcleared from the body by fast renal clearance. Therefore, the majority of conjugated drugs as wellas liposomal and micellar formulations on the market or in advanced clinical trials arePEG-containing products. Furthermore, PEG can be used as a coating material of several drugconjugates. PEG is easy availability, low cost and less toxic towards human body system. PEG with amolar mass of 200-8000 is mostly used for the conjugation of low-molar-mass drugs as well ashydrophobic drugs. Its average toxicity is 50 g per kg of human body weight. Allicin is anorganosulfur plant defensin mimetic compound, responsible for the bacteriostatic properties ofAllium sativum (garlic). It is an important phytopharmaceutical and herbal drug that is capable ofseveral biological activities including wide spectrum antibiotic action, synergy andanti-carcinogenicity. However, the most crucial issue with the compound is its stability. Hence, thepresent study mainly focused on enhancing the stability of allicin for its commercial applicabilityalong with the exploration of its antibiotic action against two chosen bacterial strain; i.e.Bacillus subtilis and Escherichia coli. To enhance stability, allicin was entrapped withinpolyethylene glycol (PEG) aggregation (PEGylated allicin). For this purpose, PEG 400 and 6000 wereused. They show spontaneous aggregation at their critical aggregation concentration (CAC). PEG 6000shows less CAC compared to PEG 400. It was observed that PEG 6000 expressed better inhibition to thebacterial growth at acidic pH (1.5 and 3) compared to PEG 400. Moreover, allicin and PEGylatedallicin established the synergistic effect with several antibiotics which is advantageous duringcombined antibiotic therapy.

Mr Anirban MukherjeeImage Delegate ID Theme Details


Research



Designation : Project Assistant

In twenty-first Century, to meet the global demand of eco-friendly sustainable energy, the production of renewable energy i.e. hydrogen, has received great focus. Hydrogen, the most promising alternative to traditional (i.e. oil, fuel, natural gas) fuel so then it can be used directly in a fuel cell and IC engines. Proton exchange membrane fuel cell or direct hydrogen fuel cell needs “on-board” hydrogen generation and storage to meet the instantaneous demand of hydrogen. In the case of practical “on-board” application hydrogen generation safety, easy to control, high hydrogen generation rate, hydrogen storage capacity are the key issues. In this context, boron-nitrogen-based (B-N) hydride compounds such as ammonia borane (AB, NH3BH3), has drawn attention due to their high hydrogen generation and storage capacity. While most B-N based compounds such as hydrazine borane (N2H4BH3) or metal borohydrides such as sodium borohydride (NaBH4) suffer from self-hydrolysis in water, AB, being the simplest B-N compound, has a high hydrogen content (19.5 wt.%), low molecular weight (30.9 g mol-1), non-toxic nature, and particularly high stability in both aqueous solutions and air. Hence, AB has a great potential for practical on-board applications in fuel cell. So far, hydrolysis has been the most effective method to achieve all 3 atoms of H2 from 1 atoms of AB even in room temperatures, although bi-metallic and mono-metallic catalyst is often required. Since its discovery, Graphene and its composites have drawn attention to a lot of researchers as a supporting material due to its electronic, mechanical, optical, thermal properties and very high surface to volume ratio. Among different metallic components, few low-cost transition metal and alloys (i.e. Cu, Co, Mn, Cr, Fe and Ni) have been widely used to furnish supported very stable and uniformly dispersed atoms on various substrates which is industrially viable for its low cost. Graphene supported nano-hybrids were synthesized varying the weight ratios and characterized morphologically along with also electrochemically using SEM, EDAX, HRTEM, XRD, XPS, Raman Spectroscopy, LSV and cyclic voltammetry, respectively. TOF (Turnover frequency) and Activation Energy also being calculated to analyze the catalytic stability and activity.

Ms JOYEETA BOSEImage Delegate ID Theme Details


Research


Organisation : NATIONAL INSTITUTE OF TECHNOLOGY


Amongst various wastewater treatment processes, membrane separation process has attracted a greatdeal of attention in recent days. For the MF, UF, NF, RO and FO technologies, the development ofmembrane material is a major area of research application. In this study, an approach was made forsynthesizing a polymeric nanocomposite flat sheet membrane by phase inversion method. Compared tothe typical membrane, it has been reported that incorporation of nanomaterials modifiesphysicochemical properties of the membrane and has great potential in resolving the problem of thetrade-off between permeability and selectivity. In our study, the 3C-SiC (Silicon carbide)nanoparticle (NP) (size range: 15-30 nm) was incorporated in two different polymers chosen as thehost material, cellulose acetate (CA) and polyvinylidene fluoride (PVDF). While the main challengewas incorporating the NP in the polymer matrix due to agglomeration and non-uniform distribution.And also the chances of leaching of NP is another matter of concern. Due to the bad consistent andinterfacial interaction, the combination of the inorganic particles with the polymer matrix is weak,therefore, for breaking down the particle agglomeration and improve the dispersibility of particlesin the polymer matrix surface modification of nanoparticle can be used effectively. There areseveral types of surface modification, and here we are focusing on chemical modification by silanecoupling agent for attaching the functional group successfully on the SiC surface. A set ofcharacterization (FTIR, FESEM, XRD, XPS) was performed to verify the presence of the functionalgroup on the functionalized SiC NP. After functionalization SiC NP showed better dispersion in theorganic solvent. For comparing the morphology and various characteristics of the different membranesFTIR, TGA, FESEM, AFM, XRD, water contact angle, mean flow pore analysis and tensile strengthanalysis were performed. Based on the results, the properties of the different modified membrane isdiscussed simultaneously. As per the obtained result, the CA membrane became more hydrophilic,probably due to the covalent interaction with the modified nanoparticle, and on the other hand,hydrophobicity of PVDF membrane increased due to the weak dipole interaction between thenanoparticle and polymer matrix in a controlled pore size range. So we can use modified CA membranefor separating protein from an aqueous solution having less foulant and more permeability capacity,and on conversely we can use the PVDF membrane for oil or another low surface tension solvents,organic solvents separation.

Ms Arundhati SarkarImage Delegate ID Theme Details


Research




Non-renewable energy sources like coal, oil, etc. are gradually decreasing and are being depleted by the overconsumption of an increasing human population. Moreover, greenhouse gas emission has made a severe impact on the environment. Hydrogen has emerged as a potential source of renewable energy and can substitute the present non-renewable source based economy. Water can be used as a source of hydrogen. Hydrogen is derived by photocatalytic water splitting, where a photocatalyst is utilised to convert solar energy to a clean fuel, hydrogen. Photocatalytic water splitting involves the generation of photo-excited electrons and holes upon absorption of photons and the reduction of water to hydrogen by the photo-generated electrons. However, the yield of hydrogen is low in this process. Rapid rate of recombination of electron-hole pairs and slow kinetics are two prime reasons for this low value of yield. Most of the synthesized photocatalysts till date are UV light active that constitutes only 4% of the solar spectrum. These problems are addressed by the development of a visible light active nano-hybrid two component photocatalytic system. The narrow bandgap of the photocatalyst is necessary for absorption of broader spectrum of light. But, for creating separate active sites for oxidation and reduction, a wide bandgap is required. Our research target is to facilitate simultaneous high redox activity coupled with a broad light absorption range. Visible light active photcatalysts, CdS (bandgap of 2.4 eV) and WO3 (bandgap of 2.7 eV), are used in this work. Graphene, having unique 2D structure displays exceptional electronic mobility, a large specific surface area and acts as an electron transporter, suppressing recombination. The photocatalysts are synthesized, characterized by various characterization techniques like SEM, FTIR, UV-Vis Spectroscopy and tested in an annular photoreactor. A significant rise in the rate of hydrogen generation is observed when compared with pure CdS.

Mr SAYANTANU MANDALImage Delegate ID Theme Details


Research


Organisation : JADAVPUR UNIVERSITY

Designation : PhD STUDENT

An energy-efficient high-performance Hybrid Hydrogen generation--fuel cell-thermoelectric generator(HG-FC-TG) system based on waste heat utilization is proposed for remote power application. AHydrogen generation unit, fuel cell, waste heat conversion devices, and an energy storage device areput forward in an HG-FC-TG hybrid system. The hybrid system is an independent power generatingsource and can be used for any remote applications like power generation in the mountain, desert,seacoast, battlefield which has limited access to the utility grid. The hydrogen fuel iscontinuously generated by hydrolysis of Sodium borohydride in the presence of catalyst above theroom temperature. Graphene supported low-cost non-noble metal-rich (zero Pt) bimetallicelectrocatalysts with novel morphology are explored as the oxygen reduction catalyst of the fuelcell. The fuel cell is operated above 1500C for enhanced performance; it not only generateselectricity but also produces high-grade waste heat due to electrochemical reaction and inbuiltheaters. To recover the high-grade waste heat into electricity and for additional power generation,thermoelectric generators, those produce electricity out of temperature differential based onSeebeck effects, are cascaded on the fuel cell. Thermoelectric waste heat retrieval from fuel cellhas been experimentally explored for the additional power generation. An experimental systemconsisting of a number of thermoelectric modules and a heat sink was built up and tested under theoperating condition of a single unit fuel cell. The power generated by an individual fuel cell andthermoelectric generators is stored in the energy storage systems. The obtained experimental resultsfor the hybrid system are validated with theoretical modelling at various parameters by the COMSOLMultiphysics. The proposed hybrid system is found to be more efficient than the stand alone-fuelcell system. The power generated by the fuel cell and thermoelectric generators is combined byauxiliary devices and stored in the batteries.

Dr Paramita DasImage Delegate ID Theme Details


Research



Designation : PDF

Most of the synthetic dyes used in textile, plastic, paint, and paper industries are toxic andcarcinogenic even at a very low concentration and these organic pollutants usually pose a seriousthreat to the environment as well as to public health. They traverse through the entire food chain,leading to bio-magnification. These toxic pollutants are continuously discharged through industrialeffluents consequently polluting the water streams which is one of the major global challenges forthe 21st century. A huge amount of resources and manpower have been involved to resolve thisproblem. Among various techniques used for removal of these toxic synthetic dyes from water,adsorption technique has proved itself as an efficient technique for the removal of hazardouscontaminants since they serve multiple purposes, viz. simplicity in operation, one-steppurification, cost-effectiveness, high productivity, easy upscaling, low energy consumption, etc. Awide variety of agricultural waste and byproducts such as orange peel, banana pith, tea leaf, pinesawdust, pineapple stem, garlic peel, coconut bunch waste, coffee husk, walnut sawdust, rice husk,neem leaf, pineapple leaf, sawdust, rice husk, pine tree leaf etc. have been explored for theelimination of toxic pollutants from wastewater since they are inexpensive, eco-friendly and canperform without leaving any detrimental effect on the environment. The present study deals with theremoval of a cationic dye, Rhodamine B using a natural adsorbent from agricultural waste. Thesorption study was carried out in a batch process. The percent dye removal was determined and theeffects of different parameters such as the quantity of the adsorbent, pH, concentration of theadsorbate and time of contact were thoroughly investigated and optimized. Under optimum conditions,it was found that the efficiency of this biodegradable adsorbent for the removal of Rhodamine B dyewas above 90%. The high efficiency of this green and low-cost adsorbents encourages its usage forthe removal of other toxic pollutants present in the industrial effluents.

Mr BIJOY KUMAR PUROHITImage Delegate ID Theme Details


Research


Organisation : RGIPTDesignation : RESEARCH

SCHOLAR

Thermal energy storage (TES) methods are considered to be one of the widely used techniques for thermal storage in buildings and industrial applications and provide new means of thermal energy management by storing thermal energy within a storage medium. Solar thermal energy and excess/waste industrial heat were the main sources of thermal energy that requires to be stored and utilize using the TES system [1]. Phase change materials (PCMs) which are classified as latent heat storage (LHS) material, are one of the efficient material for TES applications. Inorganic salt hydrates as a phase change material have the advantage of high latent heat values, high thermal conductivity and are not flammable. But, phase segregation, corrosiveness is the key downside feature that restricts its application compared to organic PCMs in thermal energy storage applications [2]. To overcome these problems during TES application, a PU-PCM composite was prepared by incorporating aqueous saturated sodium sulphate solution, inorganic phase change material, within open pores of polyurethane (PU) foam. During respective cooling/ heating thermal cycles, hydration/dehydration of crystals of Na2SO4.10H2O (inorganic PCM) occurs within pores of PU foam composite. This composite showed better thermal efficiency than normal PU foam as insulation, between both sides of composite, by maintaining a temperature difference of about 8oC in the atmospheric temperature range of 35oC to 10oC [3]. But the PCM leakage of PCM from composite was still a minor issue to this composite, which reduces its performance in the long run. An industrial-grade gelling agent was added to increase the viscosity and minimize the leakage of PCM from composite. The amount of PCM, gelling agent, the nucleating agent added was optimized, so that the PCM should have less supercooling, no phase segregation and can be applied for thermal insulation application between 25-30oC. With the optimum addition gelling agents, the PCM leakage% from composite was reduced to about 5% from about 60% (without a gelling agent). Results of the thermal performance of this composites, as an insulation layer between 45-10oC temperature ranges, show better performance.

Ms Olivia SenImage Delegate ID Theme Details


Research


Organisation : BCRCPDesignation : Researcher

Nowadays transdermal delivery for steroidal use has been widely performed for hormone replacementtherapy in menopause and recently have been used for contraception. For this treatment the doseapplied have to penetrate the skin and this can be made by both estrogens and progestins deliveredusing an appropriate solvent. Minimum amount of the dose applied topically is absorbed into thesystem. Transdermal delivery systems (TDS) are available in two types reservoir type and matrixdispersion type for drug delivery. Estradiol in combination of progestins can be used for bestcontraceptive effect. Potent progestins have to be used so that desired plasma levels can beachieved with low dose and maintain the surface of TDS. The TDS were changed daily with dosagesshowed suppression in ovulation. These applications conveniently described the suppression ofovulataion in women. TDS used for contraception ensures that these systems should be perfectlyadhesive, have tolerance locally and should be 100 % efficient. There is a lot of advantages usingthese systems and achieving these targets are very challenging.

Mr Easam Ramkishore Kumar DoraImage Delegate ID Theme Details


Research


Organisation : Nit WarangalDesignation : PhD

Surface and groundwater contaminated with heavy metals is a serious global environmental concern andhuman health as well as aquatic life. Excess of these elements receive worldwide attention becauseof its severe effects on health of aquatic cattle as well as humans. Therefore, necessary steps andpreventive measures should be taken to minimize the concentration of heavy metals in water toacceptable limits. Various methods such as floatation, ion exchange chemical precipitation, reverseosmosis, nanofiltration,ultrafiltration, coagulation, flocculation, floatation etc. However thesemethods have disadvantages such as high cost, unpredictable metal ion removal. Adsorption being verysimple, economical, specific pollutant removal and further use of low cost metal organic frameworkadsorbents for adsorption made competitive method over conventional methods for removal of hazardouscontaminants from water. Therefore Metal-organic frameworks have been explored for removal of heavymetals in wastewater due to their structural stability, low cost, high surface area, porosity,structure tunability. In this review, recent advancements in the metal organic frameworks (MOFs) asadsorbents in the removal of heavy metals from water and its advantages are discussed. Futureresearch should focus on recyclability of these materials for water treatment because of limitedwater stable metal organic frameworks.

Ms Mrigya FogatImage Delegate ID Theme Details


Research


Organisation : Rajiv Gandhi Institute of Petroleum

Technology Designation : Student

At present, the extraction rate of conventional oil reservoirs is limited to 35% after the application of primary and secondary methods. To enhance the extraction further, enhanced oil recovery methods are applied. One of these methods is CO 2 enhanced oil recovery, in which CO 2 is injected into the subsurface formations. Due to the miscibility with hydrocarbons, it provides the required enhancement in oil recovery and at the same time mitigating CO 2 emissions. However, early CO 2 channeling and breakthroughs are often encountered during oil recovery resulting reduces the oil production, which is highly undesirable. This makes it essential to have mobility control during its application and triggered a new concept of CO 2 capturing concept within a liquid which showed greater potential for oil production. Moreover, the capturing of CO 2 within nanofluid is more favorable than other conventional fluid due to the intrinsic properties of nanoparticles which is governing the reservoir properties at nanoscale. Furthermore, CO 2 assisted foams became a novel approach for oil recoveries showed more enhancement in oil production. However, these foams can be stabilized by nanoparticles, which is more suitable for oil recovery. This study provides a critical review which is fully devoted to studying different techniques associated with CO2, their capturing within nanofluids and CO 2 assisted foams followed by their utilization in subsurface application such as enhanced oil recovery.

Mr MUKKERA VAMSHI KRISHNAImage Delegate ID Theme Details


Research


Organisation : NIT WarangalDesignation : Ph.D. -

Research scholar

Textile industries use large amounts of water, and also generate large amounts of wastewater effluent. It mainly contain azodyes which amount near to half of the total amount of dyes that are even used in the other industries for various uses. Azodye contaminated water is toxic, carcinogenic, and have high COD, BOD, TOC values that can lead to the suffocation of aquatic beings. The biggest task of the industries nowadays, is to decolorize or limit the content of such carcinogens in the effluent that will be released to the environment chiefly water pools. This task is done by using many physical and chemical methods like coagulation-flocculation, adsorption, filtration, oxidation. But, since they have drawbacks of operational problems, producing more toxic end products and being expensive, the biological methods for decolorization is most favoured, which can cover up all the drawbacks. The biological methods follow the reduction of azo bond, i.e., breaking it into the aromatic amines and then, mineralizing them to less toxic end products. The process can also involve bioaugmentation, that exercise the application of microbes to the bioreactors or the polluted sites for increasing the rate of decolorization. The present review studies the decolorization employing biological methods with and without the use of bioreactors along with diverse microbes. The various conditions that effect the decolorization along with the methods of analysis are also conferred.

Ms Priyanka GhoshImage Delegate ID Theme Details


Research




Today’s world is standing on the verge of declining fossils fuels. Increasing demand of power led to a parallel increase in the usage of fossil fuels which has an adverse impact on environment. Coal based electricity generation and using petroleum as a fuel impacted our environment heavily. Development of alternative fuels to fossil fuels are therefore of great interest to deal against these environmental pollutions. Fuel cells are one of the most promising alternative renewable energy resources that produce electrical energy from the chemical energy of the fuels and the only by-products are water and waste heat. The major components of fuel cells are the electrodes and electrolytes. In this work we have developed a low lost, portable, ready-to-use, smart, phosphorous and silica based, inorganic gel paste electrolyte which can retain its properties for several months and used it in fuel cell to generate electricity. This gel paste has been synthesized in a very low cost, easy synthetic pathways. Starting from specially three main ingredients Tetraethoxysilane, Ethanol and Phosphoric acid which are very low in cost and readily available; gel paste can be formed in just less than 1 hour. Even the energy consumption in preparing the gel paste is also very low as it has been synthesized in room temperature only by stirring. This gel paste can be stored in tube for easy, smart and commercial use purpose as per requirement; when required it can be pasted on the electrodes. It is observed that the gel paste can retain its properties and physical form for several months even more than one year. This inorganic gel paste with smart, portable, handy nature, excellent properties could be a door opener in modern technologies for long term uninterrupted power supply in new generation electronics. Rural and remote areas like mountain, dessert, seacoast, battlefield which has very limited access to utility grid suffers from lack of electricity. In these areas for emergency and instant power supply, fuel cells, especially potable fuel cells are very useful. Even in extreme weather condition or natural disaster like earthquake, flood and storms, for military purposes this wireless, mobile technology works at its best. These portable fuel cells can generate sufficient power to run all electronic gadgets, charge batteries and to run automobiles.

Mr Harsh BajpaiImage Delegate ID Theme Details


Research


Organisation : CSIR-AMPRI,Bhopal

Designation : Fellow trainer

Strategic Lithium Values From Lepidolite Via Innovative Microwave Assisted Digestion And Ultrasonic Technique For Synthesizing Ultrapure Nano Lithium Compound

Harsh Bajpai, Prachal Dhok, Sarika Verma, Medha Mili, M Akram Khan, SAR Hashmi, A K Srivastava

Materials for Radiation Shielding and Cement Free Concrete Division-Council of Scientific and Industrial Research (CSIR) - Advanced Materials and Processes Research Institute (AMPRI), Hoshangabad Road, Bhopal (M.P.) 462026, India Corresponding author email: [email protected]

Abstract:- With the increasing scientific and technological interventions in various sectors over the years, the demand for lithium based materials have increased due to its wide application spectrum in the strategic areas especially in new consumer electronic battery technologies and electric cars, energy, medical, aerospace, nuclear power plants etc. Therefore, the main focus on extraction of lithium values from its various sources like Brine Sea, mineral resources and other e waste etc have been exponentially increasing day by day. The conventional process for the extraction of lithium values especially from its mineral resources requires lot of time, is cumbersome as well energy intensive. In the present work the extraction and synthesizes of high performance ultrapure nano lithium compounds has been done along with its detailed characterization using sophisticated complimentary techniques like XRD,IR,TEM,EDS etc. The novel process for the extraction of strategic lithium values from lepidolite by an innovative microwave assisted digestion and ultrasonic technique in an appropriate ration, reaction conditions and process parameters leads to the management of fines generation during processing and thus is cost saving, energy efficient, electricity efficient and time saving process and further aims at enhancing the efficiency of the developed ultrapure nano lithium compound. The synthesized nano lithium compound is useful for multifarious applications which can be used in various strategic sectors like electric vehicles, energy storage, consumer electronics and next generation batteries.

Key words:- Energy; Lithium Values; Microwave; Ultrasonication; Lepidolite ; Ultra Pure Nanoparticles. ------------------------------------------------------------------------------------------------------

Dr Imran KhanImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Sadakathullah

Appa CollegeDesignation : Assistant

Professor

ethylenediamine modified ?-Cyclodextrin is also prepared and its Cu(I) Complex is used for thesynthesis of benzoxazole derivatives via phenol and benzylamine coupling reactions, involving theintermediary of ortho-quinones. The preliminary findings of this study, reported in this work, isinteresting as catalyzing the aerobic oxygenation/dearomatization of phenols has remained anunresolved challenge in biomimetic copper chemistry for more than 50 years. Numerous biochemicalprocesses harness the energy of O2 by converting phenols into ortho-quinones which are versatilesynthetic intermediates, whose innate reactivity enables cycloaddition, condensation, addition, andredox reactions. However, the conversion of phenol into ortho-quinones currently requiresstoichiometric amounts of an oxidant other than O2.

Dr SIDDHARTHA PALImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : INDIAN

INSTITUTE OF TECHNOLOGY KHARAGPUR

Designation : POST-DOCTORAL FELLOW

Morphology switching by an external stimulus creates the possibility to detect and control theactivity and functionality of bio-molecules. The morphological conversion of unconjugated bilirubinby light stimulation is relevant to understand and apply the controlled photoisomerization process.Unconjugated bilirubin (UCB), a waste product resulting from heme catabolism, is highly sensitivetowards blue light-induced configurational conversion from (4Z, 15Z) to (4Z, 15E)-bilirubin. UCB hasa distinctly elongated nanostructure which is readily photoswitchable to spherical by external bluelight (470 nm) irradiation. Herein, the morphology alteration by blue light was nicely correlatedwith the photoisomerization of UCB, using different microscopic and spectroscopic techniques. Torestrict the other photo-incidents during photo treatment on UCB, a suitable time frame wascalibrated by monitoring the absorption, HPLC, lifetime distribution and 1H NMR studies.Furthermore, by the help of this morphological transition as a marker, UCB early-stagephotoisomerization has also been triggered by two-photon irradiation (940 nm). To the best of ourknowledge so far, the two photon induced photoisomerisation of UCB from the viewpoint ofmorphological transition is a new and unexplored area.

Ms SUMANA Y KOTIANImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : UNIVERSITY

OF MYSOREDesignation : Research

Scholar

Synthesis, Characterization and Study of Liquid Crystalline Properties of Pyrazoline Derivatives

Sumana Y. Kotian,a,* Srikantamurthy Ningaiahb, Aloir A. Merlo,c K. M. Lokanatha Rai,a,*

aDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India bDepartment of Studies in Chemistry, Vidyavardhaka College of Engineering, Mysore 570006, India cInstituto de Química, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, CEP 91501-970, RS, Brazil [email protected], [email protected]

Abstract

Liquid crystals (LCs) are intermediate phase of matter with the physical attributes of liquid, and a high-level of orientational order of solids. This property of LCs has been widely utilized for the development of LC displays and other industrial applications. The research in the past few decades shows the substantial increase in the exploring of applications of five-membered liquid crystalline heterocycles in photovoltaic devices, organic light-emitting technologies, and biological systems. Pyrazolines are five-membered heterocyclic compounds containing two nitrogen atoms adjacently and have only one endocyclic bond. Pyrazolines have been found to exhibit discotic mesophases even in the absence of disc-like molecular shape.

Keywords Pyrazolines, liquid crystals, mesophases, chloramine-T

Mr PAVEL BANERJEEImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IIT Kharagpur


The “Mother Nature” utilizes molecular self-assembly as an efficient tool to design severalfascinating supramolecular architectures from simple building blocks like amino acids, peptides,nucleobases, and pigments. The extension of amyloid hypothesis to include non-proteinaceous singlemetabolites invokes a new paradigm for the pathology of inborn metabolic disorders.1,2 Using properspectroscopic and microscopic tools, distinct assembling mechanisms of L-Phenylalanine (L-Phe) andL-Tyrosine (L-Tyr) have been established. Phenylketonuria and Tyrosinemia type II, the two metabolicdisorders, are originated due to the complications in metabolism of L-Phe and L-Tyr, respectively.Several neurological injuries involving microcephaly, mental retardation, epilepsy, motor diseaseand skin problems etc are the symptoms of these two diseases. It has been reported that toxicamyloid fibrils are formed at a high concentrations of L-Phe and L-Tyr. Our study indicates that thefibril forming mechanisms of L-Phe and L-Tyr are completely different.3 In case of L-Phe, ?NH3+ and–COO- groups of neighbouring molecules interact via hydrogen bonding and polar interactions. Onthe other hand, there is no role of ?NH3+ group in the fibril forming mechanism of L-Tyr. In L-Tyrfibril, the two hydrogen bonding partners are –OH and –COO- groups. In addition, we have alsoinvestigated the effect of three lanthanide cations on the fibrillar assemblies of L-Phe. We havealso employed 1.67 and 0.42 % beer for effective breakdown of L-Phe and L-Tyr assemblies,respectively. We have also shown that the morphology of L-Phe changes to L-Tyr in presence of2,2?-Bipyridine-3,3?-diol (BP(OH)2) and Colchicine.4 We expect this particular discussion not onlyfuel the excitement and stimulate research in this highly emerging field but also inspire broaderconcern across various disciplines which will further clarify the understanding and applications ofthe process of self-assembly of single biomolecules.

Dr RAMBABU DANDELAImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Institute of Chemical Technology- IOC

BhubaneswarDesignation : Assistant

Professor

In the past decade, X-ray crystallography and crystal engineering are playing a crucial role in pharmaceutical development. Multi-component cocrystals have considerable importance in the pharmaceutical industry to fine tune the physicochemical and pharmacokinetic properties of drugs, with solubility, dissolution, stability and bioavailability. Recently, the highest multicomponent (five) single crystals were reported in 2016 and a 6-component organic adduct in 2018. Very recently, the single crystal X-ray structure of a six component organic salt alloy (hexanary) of naftopidil (1) (an active pharmaceutical ingredient) with benzoic acid (2) and four different hydroxy substituted benzoic acids, i.e. salicylic acid (3), 2,3-dihydroxybenzoic acid (4), 2,4-dihydroxybenzoic acid (5), and 2,6-dihydroxybenzoic acid (6) is reported. The hexanary assembly originates from the observation that the binary salts of naftopidil with the above acids are isostructural. In addition to the one 6-component solid, we also describe five 5-component, ten 4-component, and ten 3-component organic salt alloys of naftopidil (1) with carboxylic acids (2-6). These alloys were obtained from different combinations of the acids with the drug. The synthetic design of the multi-component organic alloys is based on the rationale of geometrical factors (shape and size) and chemical interactions (hydrogen bonds). The common supramolecular synthon in all these crystal structures is the cyclic N+–H···O?and O–H···O hydrogen bond motif of R_2^2(9)graph set between the 2-hydroxy-ammonium group of (1) and the carboxylate anion. This ionic synthon is strong and robust to direct the isostructural assembly of naftopidil with up to five different carboxylic acids in the crystal structure together with the lower level multi-component adducts. Solution crystallization by slow evaporation provided the multi-component organic salts and alloys which were characterized by a combination of single-crystal X-ray diffraction, powder X-ray diffraction, NMR and differential scanning calorimetry techniques.

References: Dandela R.; Tothadi S.; Marelli, U. K. and Nangia, A. IUCrJ, 2018, 5, 816–822.

Dr Gopinath KhansoleImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : D. A. B. N.

Arts & Science College, Chikhali, Affiliated to Shivaji University, Kolhapur (M.S.)Designation : Assistant

Professor

Abstract: Multicomponent reactions (MCRs) are of increasing importance in organic and medicinal chemistry. MCR strategies offer significant advantages over conventional linear-type synthesis. Ionic Liquid (ILs) is productive promoters for green chemical reaction. A green, efficient procedure has been developed for the synthesis thiadiazolo [2,3-b] quinazolin-6-(7H)-one derivatives from a multicomponent one pot three molecule condensation of 2-amino-5-phenyl 1,3,4-thiadiazole, dimedone and Ionic Liquid. This protocol begin with high atom economy and lead to the formation of three rings containing one C-C, one C=N and two C-N bonds in single operation. The simplicity of enforcement, easily available substrate, scalability and good scores of environmental parameters for the binding synthetic route more worthy and efficient of besides attention. Furthermore, thiadiazolo quinazolin derivatives were screened for their Pharmacological application. These newly synthesized compounds were evaluated by their spectroscopic technique. Keywords: ILs, Green synthesis, thidazolo quinozoline, MCRs, Pharmacological Application. References: 1.M. A. Bodaghifard, M. Solimannejad, S.Asadbegi, S. Dolatabadifrahani, Res. Chem. Intermed., 2016, 42,1165. 2.A.T. Taher, H.H.Georgey, H.I.El-Subbagh., Euro.J.Med.Chem.,2012, 47,445.

Dr Vijay BhosaleImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Yeshwant Mahavidyalaya, NandedDesignation : Assistant

Professor

Abstract: Multicomponent reactions (MCRs) are of increasing importance in organic and medicinal chemistry. MCR strategies offer significant advantages over conventional linear-type synthesis. Ionic Liquid (ILs) is productive promoters for green chemical reaction. A green, efficient procedure has been developed for the synthesis thiadiazolo [2,3-b] quinazolin-6-(7H)-one derivatives from a multicomponent one pot three molecule condensation of 2-amino-5-phenyl 1,3,4-thiadiazole, dimedone and Ionic Liquid. This protocol begin with high atom economy and lead to the formation of three rings containing one C-C, one C=N and two C-N bonds in single operation. The simplicity of enforcement, easily available substrate, scalability and good scores of environmental parameters for the binding synthetic route more worthy and efficient of besides attention. Furthermore, thiadiazolo quinazoline derivatives were screened for their Pharmacological application. These newly synthesized compounds were evaluated by their spectroscopic technique. Keywords: ILs, Green synthesis, thidazolo quinozoline, MCRs, Pharmacological Application. References: 1. M. A. Bodaghifard, M. Solimannejad, S.Asadbegi, S. Dolatabadifrahani, Res. Chem. Intermed., 2016, 42,1165. 2. A.T. Taher, H.H.Georgey, H.I.El-Subbagh., Euro.J.Med.Chem.,2012, 47,445.

Mr Suman BeraImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Indian

Association for the Cultivation of Sciences


Abstract: Group I-II-V-VI semiconducting Cu12-xMxSb4S13 (M = ZnII, CdII, MnII and CuII) substituted tetrahedrites nanostructures remains a new class of multinary materials which have not been widely explored yet. Having different ions, the formation process of these nanostructures has always the possibility of formation of cross nucleations. Minimizing the reaction time, herein, a predominantly thermodynamically control approach is reported which decoupled the quaternary nucleations with their possible cross nucleations. As a consequence, possible cross nucleations were prevented and series of nearly monodisperse intriguing substituted tetrahedrite nanostructures are formed. The possible LaMer plot for this single- and also multi-materials nucleations is also proposed. Furthermore, bandgaps of all these new materials are calculated and preliminarily the applicability of these materials is tested for photoelectrochemical water splitting

Prof Ayan DattaImage Delegate ID Theme Details


Research


Association for the Cultivation of Science

Designation : Coordinator YSC

Singlet Fission (SF) is a multi-exciton generation (MEG) pathway where in a pair of triplet exciton is formed between two neighbouring chromophores staring from a singlet excitation on a molecule. This spin allowed SF process opens a new avenue for increasing the solar energy conversion efficiency for solar cells. Production of two correlated triplet states from one single exciton attracts significant attention due to its ability to harness the higher energy photons into a photovoltaic cell rather than losing this excess energy for low band gap semiconductors. Though there are several experimental reports in polyaromatic hydrocarbons (PAH) for SF, a rational design for choice of the molecular systems still remains at infancy. This lecture would address the theoretical challenges in this area namely (a) Choice of molecules which satisfy the three thermodynamic conditions of SF and (b) Crystal engineering of molecular forces in aggregates of chromophores for maximizing the SF yield. We present few studies from our laboratory on logical design of singlet fission (SF) in aggregates.

Dr Sandeep SontakkeImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Lonavala Education Trust's Dr. BNP

Arts, SSGG Commerce and SSAM Science College,

Lonavala, Pune MHDesignation : Head &

Assistant Professor

An efficient tool for the Synthesis of Novel Anti-cancer Pyrimido-Pyrimidines *Sandeep G. Sontakke1, Prashant N. Ubale2, Sambhaji P. Vartale3

1Dr.B.N.Purandare Arts, Smt.S.G.Gupta Commerce and Smt. S.A. Mithaiwala Science College, Lonavala-410403 (MS), India. 2Department of Chemistry, L. B. D. G. College, Umri, Nanded-431807 (MS), India 3P.G. Research Centre, Department of Chemistry, Yeshwant Mahavidyalaya Nanded, (MS) India Contact Author’s e-mail address: [email protected] Abstract Because of the great pharmacological perspective of the pyrimidine motif, novel pyrimido [1,2-a] pyrimidine was prepared and screened its anticancer activity. It is an interesting class of heterocyclic compounds. Pyrimidine is the core skeleton of many naturally occurring substances including vitamins and nucleic acid. Synthesis of Pyrimido-pyrimidine and its derivatives are reported in the present article. Structures of compounds were deduced by using spectroscopic techniques: IR, Mass, 1H & 13C NMR. Furthermore, an anti-cancer property of this newly synthesized parent compound was studied against Human breast adenocarcinoma (MCF-7) and human cervical adenocarcinoma (HeLa) MCF-7 cells.

References 1) Mohamad S.A.El-Gaby, Jehan A.Micky, Nadia M.Saleh, Yousry A.Ammar, Heba S.A. Mohamed. Synthesis and spectroscopic characterization of novel 2-amino-4, 5, 6, 7-tetrahydro-3H-cyclopenta[d]pyrimidine and pyrimido [1, 2-a] pyrimidine derivatives. Chinese Chemical Letters 26; (2015); 690-69. 2) Paiva, A.M.; Pinto, M.M.; Sousa, E. A century of thioxanthones: Through synthesis and biological applications. Curr. Med. Chem. 2013, 20, 2438–2457. 3) Sambhaji P. Vartale, Nagesh D. Kalyankar &Nilesh K. Halikar; An Efficient One-Pot Synthesis of Pyrazolo [3, 4-b] pyrido [1, 2-a] pyrimidine and it's Antimicrobial Evaluation. AJADD 1 ;( 2013); 022-028.

Dr Debasish KunduImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Government General Degree College at

MangalkoteDesignation : Assistant

Professor

Organoselenides are important building blocks found to be present in several biologically activemolecules and drugs. A hitherto unreported sustainable Ni/Cu dual catalysed protocol has beendeveloped for performing C-Se cross coupling with aryl, heteroaryl and vinyl halides under ligandfree conditions. The reaction is proceeding through the in situ formation of Ni(0) nanoparticle(characterized by UV and TEM) and accelarated by Cu(I) via transmetallation. Library ofdi-heteroaryl, aryl-aryl and aryl-vinyl selenides have been synthesized through this protocol. TheMechanism has been proposed through the details study of XPS, EPR, UV and in situ IR of thereaction mixture. The Protocol has been applied for the synthesis of a organoselenide that iseffective molecule against thrombocytopenia.

Dr Sapana JadounImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Lingayas

VidyapeethDesignation : Assistant

Professor

Modification of conducting polymers via functionalization has attracted considerable attention as itcan enhance the solubility as well as processability of conducting polymers which is a major problemdue to bulky and heavier groups attached in the material. The work highlights the synthesis of[Poly(o-phenylenediamine), Poly(luminol), Poly(naphthylamine), Poly(o-anisidine), Poly(carbazole)and their copolymers via ultrasonication, microwave-assisted, mechanochemical synthesis, green/solvent free synthesis for sustainable development along with their doping via some luminescentcompounds or via some dyes to tailor the functionality of these materials via functionalization ofmonomers before copolymerization to enhance their biocompatibility (non-toxic too) for using indifferent biological activities like binding of proteins and adsorption of Bovine Serum Albumin inbiosensing, Bioimaging of Leishmania donovani for the early detection of Leishmaniasis that is aworld-threatening disease. Some synthesized copolymers could be safely used for in vivo imaging ofcancer cells. While other copolymers from different donor-acceptor monomers are highly useful inOLEDs devices due to their electron and hole transporting nature and enhancement of their oscillatorstrength as well as their quantum yield achieved for use in near infrared fluorescence imaging. Somedoped polymers could be used for the detection of BSA as well as Live cell imaging revealed thatthese functionalized nanopolymers showed penetration into the cytoplasm and excellent labeling of E.coli. Hence, could be used to design tunable biomarkers by tailoring the conjugated polymer whilesome are smart polymers such as stimuli-responsive, etc. for applications such as sensing. Above allwere analyzed via NMR, FTIR, UV-Vis, Fluorescence, TEM, Time-resolved spectra, CV, DTA, TGA, XRD,and molar mass determination. These types of smart conjugated polymers are highly demanding foroptoelectronic and energy applications as well as in biomedical due to their chemical structure,extended conjugation, tuned bandgap, controlled morphology, enhanced solubility and processability.

Dr Rizwan ArifImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Lingaya's


Professor

A series of heterocyclic derivatives was synthesized by the condensation of aromatic aldehydes andvarious substituted amines in 1:1 molar ratio. These heterocyclic derivatives were characterizedthrough elemental analysis, UV-visible, Infra-Red, 1H NMR and 13C NMR spectroscopy and massspectrometry. Heterocyclic derivatives were investigated for antimicrobial activity against a panelof bacterial species Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa andStaphylococcus aureus by disc diffusion method. Results showed that heterocyclic derivatives havesignificant potential against tested bacterial strains. Interactions of Ct-DNA and potentheterocyclic derivatives were studied by absorption spectroscopy, viscosity measurements,fluorescence quenching and circular dichroism and it has been found that heterocyclic derivativescan bind to Ct-DNA via an intercalative mode. The intrinsic binding constants Kb were calculated tocompare the binding strength of heterocyclic derivatives towards Ct-DNA. To confirm the bindingability of compounds towards Ct-DNA, molecular docking study of the target compounds was carried outagainst 1 BNA dodecamer d(CGCGAATTCGCG)2. The antioxidant potential of heterocyclic derivatives wasevaluated against DPPH free radical and hydrogen peroxide.

Mr YASH JAISWALImage Delegate ID Theme Details


Research


Organisation : MANIT BhoalDesignation : Senior

Research fellow

Importance structure parameters of heterogeneous coal sample like aromaticity (fa), fraction ofamorphous carbon (Xa), degree of disorder index (DOI) as well as crystallite size and itsdistribution parameters like interlayer spacing between aromatic sheets (d002), average crystalliteheight (Lc), average crystallite diameter (La), average number of layer per carbon crystallite(Nave) were determined by using X-ray diffraction technique. Diffractograms of demineralized samplesof different rank coals were obtained by using a Cu anode K? radiation (lambda=1.54059Å) at 40 kVand 40 mA. The X-ray intensities were measured in the range of 2 degree ? 2theta ? 120 degree with astep size of 0.019 degree 2theta. The structure of the crystallite unit was determined from theScherrer equation and peak parameters deduced from whole pattern fitting. The results show that thestructure of the crystallite unit in coal is mainly controlled by the coal rank. As the coal rankincreases the average diameter of a coal crystallite unit (La) increases, the interlayer spacingbetween aromatic sheets (d002) decreases slightly, and the average height of a coal crystallite unit(Lc) increases at first but then decreases. A new diffraction peak from the crystallite unit in coalwas found at a low scattering angle in the XRD pattern (2–10 degree). This suggests a structurewith an inter-layer spacing from 1.9 to 2.8 nm exists in coal crystallites.

Mr Manas DwivediImage Delegate ID Theme Details


Research


Organisation : Rajiv Gandhi institute of petroleum

technologyDesignation : student

Removal of pollutants from industrial wastewater has become one of the most important issuesrecently for the increase in industrial activities, especially for heavy metals and radionuclides.Since the big nuclear accident at Fukushima, Japan in 2011, a large number of radionuclides werereleased into water, soil and air, and the hazardous influence of radioactive wastewater has drawnmuch attention all over the world. Among radionuclides, 137Cs is considered the most abundant andhazardous due to diverse sources and relatively long half-life. Furthermore, it can be easilyincorporated into terrestrial and aquatic organisms because of its similar chemical characteristicswith potassium. Present Work reports removal of cesium ions from aqueous solution of high levelwaste using the Carboxylic-Acid based various hydrophobic deep eutectic solvents, which are greensolvents and formed from a eutectic mixture of hydrogen bond donor (HBD) and hydrogen bond acceptor(HBA). And maximum separation is observed when carboxylic-acid-based DES has ionic character. Thischarge transport properties resemble those of a protic ionic liquid.

Dr DEBASHIS MALLICKImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Mrinalini Datta

MahavidyapithDesignation : Assistant professor in Chemistry

Structures and light induced photochromism of Zn(II), Cd(II) and Hg(II) metal complexes of 1-alkyl-2-(arylazo)imidazoles and DFT computation Dr.Debashis Mallick* Department of Chemistry, Mrinalini Datta Mahavidyapith, Kolkata-700051. E-mail: [email protected] Abstract: Reaction between MX2 (M=Zn(II), Cd(II), Hg(II) and X= Cl, Br, I) and 1-alkyl-2-(phenylazo)imidazole (RaaiR/) in MeOH have isolated [M(RaaiR/)2X2] or [M (RaaiR/)(µ-X)(X)]2 depending upon the reaction condition . The structures have been established by spectral (IR, UV-Vis, 1H-NMR) data and the confirmation have been done by single crystal X-ray diffraction studies. UV light irradiation in DMF solution of complexes shows trans-to-cis (E to Z) isomerisation of coordinated azoimidazole. The reverse transformation, cis-to-trans, is very slow with visible light irradiation. Quantum yields (?t?c) of trans-to-cis (E to Z) (E to Z) isomerisation are calculated and free ligand shows higher ? than that of respective complexes. The cis-to-trans isomerisation is a thermally induced process. The activation energy (Ea) of cis-to-trans (Z to E) isomerisation is calculated by controlled temperature experiment. The effect of anions (Cl-, Br- and I-) on the rate and quantum yields of photochromism is established. Slow rate of photoisomerisation of complexes compared to free ligand may be associated with increased mass and rotor volume of the complexes. However, the rate of isomerisation follows the sequence [M(RaaiR/)2Cl2] Keywords: Zn(II), Cd(II), Hg(II) complexes, ligand, x-ray structures, photoisomerisation, DFT computation. References: 1. Sarker, K. K.; Chand, B.G.; Suwa, K.; Cheng, J.; Lu, T.H.; Otsuki, J.; Sinha, C..Inorg Chem.2007,46,470-480. 2. Mallick.D.; Nandi,A.; Datta,S.; Sarker,K.K.; Mondal,T.K.; C. Sinha,C. Polyhedron, 2012, 31, 506–514. 3. Naskar, K.;Maity,S.; Jana,S.;Dutta,B.; Tanaka, S.; Akitsu,T.; Mallick,D.; C. Sinha,C. Cryst. Growth & Design, 2018, 18, 2986-2997. 4. Sen,C.; Mallick, D.; Patra,C.; Roy,S.; Sinha,R.K.; Ghosh,R.; J.Mondal,J.A.; Palit,D.K.; C. Sinha,C.Polyhedron, 2016, 117,463-477.

Mr Aminur khanImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Alaih


Scholar

Practical access to diversely functionalized carbazoles has been developed by consecutive Cu-catalyzed Chan-Lam N@arylation of various o-iodoanilines and boronic acids, and Pd-catalyzed intramolecular aryl C@H activation of 2-iodo-N-arylanilines. Use of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as base was found beneficial for both steps. In the Pd-catalyzed C@H activation step, DBU acts as ligand as well as base, resulting in improved functional tolerance and higher yields than those observed with inorganic or other nitrogen bases. This DBU-assisted sequence offers access to a variety of carbazoles with various electron-donating and electron-withdrawing substituents, including halogens or other reactive functional groups. Twentyseven cabazoles with various substitution paterns, including two naturally-occurring carbazoles - clausine L and clausine H - have been successfully synthesized using these DBU-promoted metal-catalyzed coupling reaction. A Khan R Karim S Alam H Dhimane ChemistrySelect 2019, 4, 6598 –6605

Ms Sneha TidkeImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : UDPS, Nagpur


There has been considerable interest for medicinal chemist in development of a promising target fornew drug development. Quinoline is one of the potent pharmacophore having diverse biologicalactivity. Considering the biological importance of Quinoline nucleus as an antidepressant, it wasthought to synthesize novel Quinoline derivatives as antidepressantagents.3-{3-[(7-Chloroquinolin-4-yl)amino]propyl}-2substituted-1,3-thiazinan-4-one derivatives wasevaluated for antidepressant activity. Present research a novel series of synthetic Quinoline havebeen synthesized after 3DQSAR studies. (PDB code: 6AWP). Antidepressant activity was performed byforced swimming test (FST) to get the percentage decrease in immobility duration (%DID) of thesynthesized compounds. Synthesized derivatives (4b,4d,4f and 4i) exhibited good anti-depressantactivity due to presence of electron withdrawing groups (chloro and nitro) at-p,-o and-m position ofthe phenyl ring where as compounds showed moderate activity when compared with standard drug(Fluoxetine). Thus, the conclusion can be made that the Quinoline moiety can exhibit a goodantidepressant activity.

Dr Santosh KambleImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Government

AidedDesignation : Assistant

Professor

Hydrotrope as a reusable and ecofriendly catalyst for sutainable synthesis of 5-aminopyrazole-4-carbonitrile in aqeous Aboli Sankpal, Avdhut Kadam, Pramod Bansode, Bipin Shinde, Santosh Kamble* Yashavantrao Chavan Institute of Science (Autonomous), Satara, Maharashtra, India e-mail address: [email protected]

Abstract: We are report here an efficient and green protocol for the synthesis of 5-aminopyrazole-4-carbonitrile from three component condensation of Phenylhydrazine, aldehyde, malanonitrile using NaPTS as catalyst in aqueous medium. In these environmentally conscious days there is need to use eco-friendly greener technologies such as solvent free , microwave, ultrasound, use of room temperature. Hydrotrope in aqueous medium is sustainable catalyst for organic transformation. It is reusable and shows remarkable catalyst actvity during organic synthesis.Use of water has emerged as a versatile solvent for organic reaction, it is readily available, inexpensive, environmentally benign, neutral and natural solvent. Multicomponent reaction in water are of outstanding value in organic synthesis and green chemistry. The significant features of this article are short reaction time, provide excellent yield , avoide toxic solvent and use of water as green solvent.

References: 1. Xiong, W.; Chen, J.; Liu, M.; Ding, J.; Wu, H.; Su, W.;. J. Braz. Chem. Soc. 2009, 20, 367-374. 2. Curini, M.; Rosati, O.; Campagna,V.; Montanari, F.; Cravotto, G.; Boccalini, M.; Synlett, 2005, 19, 2927-2930. 3. Chen, X.; She, J.; Shang, Z.; Wu, J.; Wu, H.; Zhang, P.; Synthesis, 2008, 21, 3478-3486. 4. Kamble, S.; Kumbhar A.; Jadhav, S.; Salunkhe, R.; Procedia Material Science, 2014, 6, 1850-1856.

Mr Shyamal kumar MondalImage Delegate ID Theme Details


Research


Institute of technology (Indian School of Mines) DhanbadDesignation : Research

scholar

Study the reducibility of iron ore with coke by using different additives by thermogravimetric method. Shyamal Kumar mondal1, D D Pathak,2 Jagdish3 1,2 Indian Institute Of Technology (Indain School Of Mines), Dhanbad, India 3 CSIR-Central Institute Of Mining & Fuel Research, Dhanbad, India

Abstract Iron ore is the main source of primary iron required for the world iron and steel industries. It is essential to produce steel. Four main types of iron ore deposits these are magnetite, titan magnetite, massive hematite and pisolitic iron stone deposits. Iron ores are hematite, Fe2O3and magnetite, Fe3O4 these can be reduced to iron by heating them in blast furnace with carbon in the form of coke. It is very important that not only increase the productivity of plant but also produce a better quality iron with lower fuel consumption and also decrease in reduction time. The reducibility of iron ore depend on factor like temperature of reaction, lump size, porosity of the ore, coke quality, and the chemical composition of both the iron ore and coke. The larger size iron ore pellet decrease the reducibility, same as more porosity increase the reduction rate, with increase in temperature reducibility also get increases. Low ash, high calorific value and low moisture content coke is also increase the reducibility of iron ore. The reducibility of iron ore with coke in a blast furnace process is also affected by some different organic or inorganic additives. Additive which are act as catalyst in blast furnace increase reduction rate with good quality of iron and decreasing reduction time with saving fuel. This paper describe about different additives which is used in blast furnaces process.

Mr Debajyoti DebnathImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Presidency

UniversityDesignation : PhD student

Theoretical modelling and transport phenomena of Janus particle Debajyoti Debnath* and Dr.Pulak Kumar Ghosh Department of Chemistry, Presidency University, 86/1 College Street, Kolkata 700073, India Email-id: [email protected] [email protected] Self-propelled Janus particles are a class of micro-sized particles which can move by extracting energy from their surrounding suspension medium. This type particles are named after the two faced Roman god as they possess two distinct faces with different chemical or physical properties [1, 2]. Due to self-propulsion, Janus particles can diffuse almost an order of magnitude faster than normal Brownian particles [3]. Amplitude of diffusivity of Janus particles depends on the self-propulsion mechanism and their shape, size and chirality. A Janus particle can tow a passive cargo by binding it to form a self-propelling dimer. Hydrodynamics interaction determine thestable position of the cargo relative to the axis of the active dimer’s head.Based on the Langevin description,[4] we proposed a general model which can describe dynamics of any type of self-propelled Janus particles. We show both analytically and as well asnumerically [4] that diffusivity of Janus particles strongly depend on the model parameters. Janus particle coupled to a cargo exhibits optimal towing capability only in the puller and pusher configurations, whereas in all other configurations it drives a chiral dynamics, which suppresses the motility of the swimmer-cargo system. Our results would be useful to synthesize Janus particles with desire transport properties for application in nano-technology and medical sciences. References: [1] H-R. Jiang et al., PRL, ,2010, 105, 268230-1 - 268230-4 [2] W. F. Paxton et al., Angew. Chem., Int. Ed., 2006, 45, 5420-5429 [3] G. Volpe et al.,, Soft Matter, 2011,7, 8810-8815 [4] D.Debnathet. al., Soft Matter, 2016,12, 2017-2024 [5]D.Debnathet. al.,J.chem.phys, 2016,145,191103 .

Mr Lalit PundImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Taywade

College of Pharmacy, Koradi, Dist:-Nagpur


Abstract The development of metal based drugs with promising pharmacological application and may offer unique therapeutic opportunities. The advances in inorganic chemistry provide better opportunities to use metal complexes as therapeutic agents because of mode of action of metal complexes on living organism is differing from non metals. The lipophilicity of the drug is increased through the formation of chelates and drug action is significantly increased due to effective permeability of the drug into the site of action. The fluoroquinolones are synthetic antibiotics, active against aerobic Gram (-ve) and Gram (+ve) microorganisms. Fluoroquinolones possess 3-carboxylate group and 4-keto group which are essential for formation of metal complex. Fe(III)complexes of fluoroquinolone in presence of neutral bidentate ligand (N-N) donors 1,10-Phenanthroline 2,2’dipryidyl have been synthesized. All the metal complexes were confirmed by physiochemical parameters and spectroscopic data. The stability study of all novel complexes were evaluated as per ICH guidelines and all the complexes were found to be a stable. All the complexes were evaluated for their antibacterial activity against two different microorganisms (Escherichia coli and Staphylococcus aureus) the best inhibition has been exhibited against Escherichia coli Compared to fluoroquinolone alone. Fe(III)-Ciprofloxacin-1,10-Phenanthroline Complex and Fe(III)-Norfloxacin-2,2’diprydiyl Complex shows better antibacterial activity, as compared to respective fluoroquinolones against Staphylococcus aureus and Escherichia coli.

Mr NASIM AKHTARImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IIT Guwahati

Designation : Reserch Scholar

Synthetic anionophore research has drawn the attention of many chemist, biochemist and as well as supramolecular chemist as this area has a huge impact on therapeutic application. Ion transportation across the cell membrane plays a pivotal role in regulating the various physiological function like cell signaling pathways, proliferation, ion-homeostasis, cytosolic pH and other cellular processes. The Chloride channel is one of the most important pore-forming membrane protein that allows the passive transport of Cl- ion across biological membranes. It is essential for the regulation of cell volume, trans-epithelial transport of salt and water, modulation of the electrical excitability in neurons. Even a small aberration in chloride channel can overwhelm these cellular processes and may cause lot of deadly disease like myotonia, best disease, epilepsy, cancer and cystic fibrosis. Recent studies showed that by disrupting cellular ion homeostasis, the synthetic Cl- ion transporters can induce apoptosis in cancer cell lines, leading to a revived attention for synthetic Cl- ion transporters. However, most of the developed aninophores failed to fulfill the intended purpose due to their undesired toxicity. Inspired by the structure and biological activities of natural products, we synthesized a small series of squaramide and thiourea derivatives of quinine and investigated their anion transport properties. The Cl- ion binding properties of the quinine derivatives correlate well with their Cl- ion transport activities. The involvement of quinuclidine moiety for the cooperative interactions of H+ and Cl? ions with these thiourea or squaramide moiety results in an effectual transport of H+/Cl? ion pairs across the lipid bilayer. The interference of ionic homeostasis by the potent Cl- ion carrier selectively induces cancer cell death by promoting the caspase-mediated intrinsic pathway of apoptosis. In vivo assessment of the potent ionophore showed an efficient reduction in the tumor growth with negligible immunotoxicity to other organs.

Mr Viruthasalam MaruthapandianImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : CSIR - Central

Electrochemical Research Institute

Designation : CSIR - Senior Research Fellow

The increasing energy crisis and global environmental issues in relation with the fossil fuelutilization and CO2 emission. Hence, searching of abundant alternative energy resources with highenergy density and affordable cost and environmental begin is emerged in the past decade. In thiscontest, hydrogen (H2) has considered as efficient alternative in the energy sector of fuel cell,synthetic chemical production feedstock. Generation and storing of H2 is important in the pure formthan compared conventional intensive energy consuming, pollution emission and impure steam reformingand coal gasification process. Electrochemical/Photochemical water splitting (ECWS/PCWS) offers away of storing of renewable energy as a chemical fuel (H2) and easy generation of industriallyimportant H2 in higher pure form in pollution free manner. In the electrochemical water splittingprocess, 4e- transfer oxygen evolution reaction (OER; 4OH- ? 2H2O + O2 + 4e-) on anode is energyintensive than compared to 2e- transfer hydrogen evolution reaction (HER; 2H2O + 2e- ? H2) on thecathode. Hence, ECWS process requires excessive overpotential (?) from the theoretical potential. Anappropriate anodic and cathodic electrocatalysts was to minimise ? and increase the efficiency ofwater splitting process such as IrO2, RuO2 and Pt/C in acidic medium. Higher cost and lower inavailability of precious metal catalysts minimize the wider commercialization of ECWS process.Development of low cost, active and efficient catalysts is crucial for the progressivecommercialization of ECWS process. In the study, we have designed and developed abundant Fe basedcatalyst substrate and host for the OER by electrochemical treatment. Designed, developed catalystand other counters physic-chemical and electrochemical characteristic were analysed systematically.The developed catalyst showed a lower ? of 267 mV at 10 mA?cm?2 with a Tafel slope of 66 mV?dec?1,and good stability in alkaline medium. The results suggest that reason beside catalyticcharacteristics of designed catalyst and counters, a possible way to utilize the proposed Fe basedcatalyst substrate as catalyst and as a host for OER.

Ms sushma raniImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Guru

Jambheshwar University of Science and Technology,

Hisar, Designation : Research

Scholar

In the present work, a robust silver nanoparticle-based electrochemical sensor for sensing the4-nitrotoluene (4-NT) has been described. The silver nanoparticles were synthesized usingsonochemical technique and their purity, morphology and stability were established by Transmissionelectron microscopy (TEM), scanning electron microscopy (SEM), Energy-dispersive X-ray, X-ray powderdiffraction and thermogravimetric analysis; SEM and EDX analysis revealed an interesting structureof AgNPs containing 4-NT, different from the usual AgNPs. The synthesized AgNPs were embedded overAu electrode for electrochemical based efficient sensing of 4-nitrotoluene (4-NT) in real water.Overall, the results showed that the proposed AgNPs/Au electrode presents an efficient option fordetecting the lowest concentration of 4-NT where in the sensor displays good reproducibility,stability, and selectivity toward the analytes in real sample analysis.

Dr Amrit MitraImage Delegate ID Theme Details


Research


General Degree College: Singur


Abstract: Designing and characterisations of small molecule environment sensitive fluorophores are extremely significant in the viewpoint of bio-chemical and bio-physical studies. They are extremely precious owing to their capability to probe micro-environments which can decipher bulk information in the study of molecular biology, drug discovery, material science, tissue diagnostics, environmental indicators, enzyme substrates and cellular staining agents. Although numerous fluorophores are known in the form of coumarins, fluoresceins, cyanines, oxazines, pyrenes, quinines, bodipy dyes etc., the quest for newer ones is still on as they are extremely essential to visualise a biochemical process. Our research venture involves synthesis and photo-physical studies of a new family of fluorophores having keto-tetrahydrocarbazole framework. The origin of this research work dates back to approximately three years. There has been a surprising observation while synthesising several methoxy and methylenedioxy derivatives of keto-tetrahydrocarbazole in the viewpoint that, they emit fluorescence. This observation has been the backbone of this research work and demanded exhaustive photophysical and photobiological studies of methoxy and methylenedioxy derivatives of keto-tetrahydrocarbazole. It is worthwhile to mention that keto-tetrahydrocarbazoles are important synthetic precursors to obtain biologically active carbazole derivatives. Several members of keto-tetrahydrocarbazole family show promising synthetic importance as intermediates for the synthesis of naturally occurring, biologically active carbazole alkaloids and carbazoloquinones. Prominent biological activities of carbazole alkaloids have always been an inspiration for us to study the growth and development of keto-tetrahydrocarbazole family as the members have the potentiality to act as bio-active units. Out of many sophisticated methods, here we have followed Japp-Klingemann reaction to obtain desired hydrazones and then Fischer Indole Cyclization to achieve the said skeleton. Our initial strategy has been to synthesise various fluorophores having keto-tetrahydrocarbazole skeleton and to study their photophysics in different homogeneous solvents, various binary solvent mixtures and under various micro-heterogeneous environments like micelles, reverse micelles, cyclodextrins and serum albumins. Apart from exploring these territories, we have made intent to monitor photoinduced electron transfer in diverse environments from aliphatic or aromatic amines to keto-tetrahydrocarbazoles if any. Inspired by these studies, we have made a foray into the synthesis of some new fluorophores having ?-hydroxy acetic acid moiety in place of methoxy group at C6 position of keto-tetrahydrocarbazole skeleton. Acid functionality thus generated can be tagged with bio-molecules leading to the development of probable synthetic bio-markers.

Ms RIMPA CHATTERJEEImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : INDIAN

INSTITUTE OF TECHNOLOGY KHARAGPUR

Designation : Senior Research Scholar

Polymer membranes are of great technological interest for a range of molecular separations. The numerous polymers currently used as gas separation membranes have a tendency to result in permeability/selectivity relationships that are limited by an upper bound or Robeson line. Aromatic polyimides (PIs) can be used as a membrane material because of their outstanding set of physical properties. Polymers containing 9,10-dihydro-9-oxa10-phosphaphenanthrene 10-oxide (DOPO) are attractive due to their superior thermal properties, low flammability, organo-solubility, adhesion to metal and atomic oxygen resistance. Phosphaphenanthrene skeleton is relatively free of conformational stress that results in a large bulky structure which inhibits the packing of polymer chains. In the present investigation a phosphaphenanthrene skeleton containing diamine was synthesized that leads to a series of new processable poly(ether imide)s PEIs when reacted with several commercially available dianhydrides. The polymers were characterized thoroughly by different analytical techniques. The membranes were prepared directly by the thermal imidization of the poly(amic acid)s following a programmed heating up to 300 oC. The membranes were transparent and flexible. The PEIs showed high glass transition temperature (T g up to 261 oC), high thermal stability (up to 416 oC under air) and good mechanical properties (Tensile strength up to 91 MPa and elongation break up to 18 %). The membranes showed high gas permeability (PCO2 up to 175 and PO2 up to 64 barrer), high permselectivity (PCO2/PCH4 up to 51 and PO2/PN2 up to 10) and some of the polymers surpass the 2008 upper bound drawn by Robeson. Molecular dynamics simulation of the polymers were done using an atomistic model that showed good agreement between the size distribution free volume and gas transport properties. This study provides an insight on the diffusion behavior of gas molecules in polymer membranes and was consistent with the experimentally obtained diffusion behavior.

Mr GOVIND PORWALImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : CSIR-NCL,

PUNEDesignation : Research

Scholar

Product selectivity in aqueous phase phenol hydrogenation on well-defined supported Pdnanostructures (spheres, cubes, and octahedra) was studied using defined experiments and densityfunctional theory (DFT) simulations. On Pd spheres and octahedra, the reaction initially showed highselectivity (in the first 3 h, at 363 K and 5 bar H2 pressure) toward the partially hydrogenatedproduct cyclohexanone. On prolonged operation (>20 h of reaction time), a shift in the productselectivity (up to 100%) toward the completely hydrogenated product cyclohexanol was observed on Pdspheres and octahedra. In contrast, the reaction on Pd cubes, which only had {100} facets, showed ahigh selectivity (?90%) toward the product cyclohexanone even after 40 h, at the same reactionconditions. Since the {111} facets are expected to be the majority sites on a spherical particle, weattribute the selectivity trend observed on spherical Pd particles to be primarily controlled by theselectivity trend on the Pd{111} facets. This observation was further confirmed on performing thehydrogenation reaction on a mixture of Pd cube and Pd octahedron particles in a ratio of 25:75(representing the site ratio of a spherical particle). DFT simulations provided a mechanisticinsight into the reactivity of the two different facets ({100} and {111}) toward phenolhydrogenation. The calculations revealed that the selectivity significantly depended on theactivation barriers involved in cyclohexanone hydrogenation on the Pd{111} facets (77 and 57 kJ/mol)as compared to those on the Pd{100} facets (97 and 101 kJ/mol).

Mr Sumit B. ShejulImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Dr.

Babasaheb Ambedkar Marathwada University


In the present work, successful implementation of [DBUH] [OAc] catalyst and ultrasonication energyhas been employed for the synthesis of substituted pyrazole. [DBUH] [OAc] as a catalyst incombination with ultrasound irradiation technique is reported first time for the synthesis ofsubstituted pyrazole. The comparison between conventional as well as ultrasonication method isdiscussed in detail. Furthermore, remarkable advantages of this synthetic strategy over the othersynthesis methods were also concluded. Notable advantages of this synthetic approach over others areeasy and proficient route of synthesis, utilization of ionic liquid, employment of non-conventionalenergy source like ultrasonication and reduction in reaction times. Notable advantages of thissynthetic approach over others are 1. The procedures described here are easy, mild, and proficient,2. Utilization of ionic liquid, 3. Employment of non-conventional energy source (ultrasoundirradiation) which offers improved energy balance in comparison with those of conventionalperformance, 4. Reduction in reaction times, 5. Simple and easy work-up procedure etc.

Dr DHANANJAY DEYImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IISER

MOHALIDesignation : post doc

Abstract: An efficient transition-metal-free C-C cross-coupling reaction has been developed bysimple organic redox active molecule which providing a new and more straightforward method via aradical process. For C-C cross coupling reaction used transition-metal catalysts are normally veryexpensive, toxic to different extents, removal of transition-metal residues from desired products isquite challenging, usually sensitive to air and moisture. Transition metal free cross couplingreactions, which employ similar starting materials and give desired products, while during theprocess no transition-metal catalysts were used. Having inspiration from these concept, we have beenused a simple organic redox active molecule as a catalyst for C-C cross coupling reaction. In thiswork, we will present reaction conditions as well as details mechanistic study. This moleculeemployed as an efficient catalyst for single electron transfer based C-C cross coupling reactions.

Mr Abdul Hakeem AnwerImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Aligarh

Muslim University, Aligarh, india

Designation : Ph.D. Scholar

Background: Recently, with advancement in technology, biofuels have gained attention as a bio-sustainable resource by powering microbes with electrical energy and this helps in reducing our dependence on fossil fuels. In the last 10 years, one of the bioelectrochemical approach that has been developed is microbial electrolysis cell (MEC). It’s a potentially interesting green technology to tackle energy shortage and global warming. Fabrication of superior and cost-effective cathodic materials is vital in manufacturing sustainable microbial electrolysis cells (MECs) for biofuels production. MECs offers a new solution to emerging environmental issues related to waste water treatment and energy and resource recovery. However, this technology is still in its period of early development.

Problem: There are two main problems that the world is facing today, one of them is the energy crisis and the other is the pollution. We know that energy is a basic segment in the improvement of any country. As the worldwide energy utilization was approx. 520 quadrillion BTUs (British thermal Unit) in 2010 and is relied upon to increment by 56% (820 quadrillion BTU) by 2040. Now, 78% of our worldwide energy utilization originates from non-renewable sources like, petroleum, natural gas, coal and that exclusive 19% of the current energy originates from renewable power sources

Methods: In the present study, a novel manganese dioxide (MnO2) coated felt cathode (Mn/CF) has been developed for MECs using electrodeposition method via potentiostat. MnO2 is considered to encourage exogenous electron exchange and, in this way, improves the reduction of carbon dioxide (CO2). MnO2, as a cathodic catalyst, enhances the rate of biofuel production, electron transfer, and significantly reduces the cost of MECs.

Result: A maximum stabilized current density of 3.70 ± 0.5 mA/m2 was obtained in case of MnO2-coated Mn/CF based MEC, which was more than double the non-coated carbon felt (CF) cathode (1.70 ± 0.5 mA/m2). The dual chamber Mn/CF-MEC achieved the highest production rate of acetic acid (37.9 mmol/L) that was significantly higher (43.0%) in comparison to the non-coated CF-MEC. The cyclic voltammograms further verified the substantial enhancement in the electron transfer between the MnO2 coated cathode and microbes.

Conclusion: The obtained results demonstrate that MnO2 interacted electrochemically with microbial cells and enhanced the extracellular electron transfer, therefore validating its potential role in biofuel production. The MnO2 coated CF further offered higher electrode surface area and better electron transfer efficiency, suggesting its applicability in the large-scale MECs.

Mr Nirmalya PradhanImage Delegate ID Theme Details


Research



The improvement of body’s own immune system is considered as one of safest approach to fightagainst cancer and several other diseases. Excessive catabolism of the essential amino acid,L-tryptophan (Trp) assists the cancer cells to escape normal immune obliteration. The formation ofdisproportionate kynurenine and other downstream metabolites suppress the T cell functions. Blockingof this immunosuppressive mechanism is considered as a promising approach against cancer,neurological disorders, autoimmunity and other immune-mediated diseases.1 Overexpression ofindoleamine 2,3-dioxygenase 1 (IDO1) enzyme is directly related with the induction ofimmunosuppressive mechanism and represents an important therapeutic target. Several classes of smallmolecule-based IDO1 inhibitors have been already reported, but only few compounds are currentlybeing evaluated in various stages of clinical trials as adjuvants or in combination with chemo- andradiotherapies.3 In the quest for novel structural class(s) of IDO1 inhibitors, we developed aseries of 4,5-disubstituted 1,2,3-triazole derivatives.2 The optimization of triazole scaffold andcomprehensive biochemical and biophysical studies led to the identification of triazole compounds aspotent and selective inhibitors of IDO1 enzyme with IC50 values at a low nanomolar level. Thesepotent compounds also showed strong IDO1 inhibitory activities in MDA-MB-231 cells withno/negligible level of cytotoxicity. The T cell activity studies revealed that controlled regulationof IDO1 enzyme activity in the presence of these potent compounds can induce immune response againstbreast cancer cells. The compounds also showed excellent in vivo antitumor efficacy of TGI = 79-96%in the female Swiss albino mice. As a consequence, this study describes the first example of4,5-disubstituted 1,2,3-triazole based IDO1 inhibitors with potential applications forimmunotherapeutic studies

Mr BEERBAL PARMARImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : CSIR AMPRI

BHOPALDesignation : PROJECT

ASSISTANT

Abstract: - In this work, we have determined percentage chemical composition of marble waste collected from different areas of Rajasthan by using Atomic flame photometry. Flame photometry is a branch of atomic spectrometer in which the species examined in the spectrometer are in the form of atoms. Flame photometry is suitable for qualitative and quantitative determination of several cations, especially for metals that are easily excited to higher energy levels at a relatively low flame temperature (mainly Na, K and Ca). In this study comparative results were drawn for marble waste samples collected from seven different districts of Rajasthan like, Makrana, Chhitorgarh, Ajmera , Rajsamand , Udaipur, Jaipur and Kishangarh. Atomic flame photometry results validate the presence of calcite in all seven samples and the maximum concentration of calcite was found in the sample from Makrana site while minimum was reported in marble waste from Kishangarh. This study is therefore useful in understanding the chemical composition of marble waste which can then be potentially utilized in applications like formulation of hybrid composites, agricultures, and Cement industries.

Mr ANKIT SINGH BARTWALImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Department of

Chemistry, HNB Garhwal University, Srinagar Garhwal,

UttarakhandDesignation : Research

Scholar

Abstract: Rhododenderon campanulatum is a decumbent shrub of Ericaceae family. In India it is distributed (in alpine region from 3000m-3640m asl) in Jammu and Kashmir, Uttarakhand and Himachal Pradesh. The identification of this plant is white color of flowers, So the vernacular name of R.campanulatum is White Burans and Shargal. In the screening of phytoconstituents of R.campanulatum, the methanolic and aqueous extract of plant material were used. In the phytochemical investigation of R.campanulatum we found the presence of taraxerol, betulinic acid, quercetin, rutin, coumaric acid, ursolic acid acetate etc. It is used for fuel and charcoal, but it is toxic in nature. Flowers and bark are medicinal for digestive and respiratory disorders while Roots of R.campanulatum used as medicine to alleviate many disease like boils cold, cough, headache, rheumatism, sciatica, skin disease, syphilis, tonic, fever. The aqueous and alcoholic extract of leaves of R.campanulatum was analyzed for antimicrobial, antioxidant, and immunomodulatory activities. In the present study we have used the green method in the synthesis of silver nanoparticles. In green synthesis of Ag-NPs, the silver nitrate solution and the aqueous plant extract were mixed well in the ratio 9:1 respectively, then the metal ion present in the solution reduced as Ag+1 to Ag0 within 70-74hours. In the spectrophotometric observation the ?max peak of Ag-NPs of R.campanulatum leaves (RCL) obtained at 431nm for 1mM(RCL1:9), 473nm for 2mM(RCL1:11), 452nm for 3mM(RCL1:9), while the ?max peak of Ag-NPs of R.campanulatum flowers (RCF) obtained at 464nm for 1mM(RCF1:9), 492nm for 3mM(RCF1:9), 472nm for 5mM(RCF1:9). The observation of synthesized Ag-NPs of leaves and flowers of R.campanulatum are characterized by UV-VIS, XRD, SEM, EDX etc.

References: 1. R. D. Gaur, “Flora of the District Garhwal North West Himalaya (With Ethnobotanical Notes), Trans Media Srinagar (Garhwal), I-edition July-1999, (P. No-31, 32, 133, and 199). 2. R. M. S and S. S., “Diversity , indigenous uses and conservation status of medicinal plants in Manali wildlife sanctuary , North western Himalaya,” vol. 10, no. July, pp. 439–459, 2011. 3. A. Paudel, S. Panthee, S. Shakya, S. Amatya, T. M. Shrestha, & M. P. Amatya. Phytochemical and antibacterial properties of Rhododendron campanulatum from Nepal. Asian Journal of Traditional Medicines., 2011,6(6).

Ms Oindrila BiswasImage Delegate ID Theme Details


Research



Membrane embedded channels and carrier-type proteins assist small molecules and ions to easily crossthe hydrophobic core of the membrane bilayer of the living systems.1 Selective transport of anionssuch as HCO3-, Cl-, PO43-, and SO42- plays a critical role in regulating ion-homeostasis, cellularpH, signal transduction, and other cellular processes.2, 3 However, dysregulation of cellular Cl-ion transport system is related to several diseases (i.e., channelopathies) such as myotonia,epilepsy, kidney disorders, cystic fibrosis, and others.4 There is growing evidence that thesynthetic mimic of the natural transporter systems has the potential to replace the defectivenatural transport system for the clinical management of channelopathies. Thus, it is essential todevelop and investigate the activities of synthetic transporters to treat these channelopathies byovercoming the interrupted activities of the natural transporters. Small molecule-based syntheticCl- ion transporters are relishing a revived attention because of their recently discovered roletowards the anticancer activity. Herein, we showed that the anticancer agents; PITENINs have anefficient transmembrane Cl- ion transport activity. Theoretical calculations, 1H NMR titration, andspectrophotometric analysis suggest that the PITENINs strongly bind with the Cl- ion. Thelipophilicity and the presence of acylthiourea, and phenolic OH moieties in the compounds play acrucial role in the transport of Cl- ion across the membrane bilayer. Among the tested compounds,PIT-1 and DM-PIT-1 showed higher Cl- ion selectivity and transport efficiency. Mechanistic studiesdemonstrated that the potent compounds, PIT-1 and DM-PIT-1 follows H+/OH- > Cl- transport pathway.Cellular activity studies showed that the disruption of Cl- ion homeostasis by PIT-1 and DM-PIT-1preferentially promotes apoptotic cell death.

Dr Richa AroraImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Shivaji

College, University of DelhiDesignation : Assistant

Professor

Pharmacophore modeling and atom based 3D-QSAR have been developed on N-acylglycino- andhippurohydroxamic acid derivatives, which are known potential inhibitors of urease. This is followedby virtual screening and ADMET (absorption, metabolism, excretion and toxicity) studies on a largelibrary of known drugs in order to get lead molecules as Helicobacter pylori urease inhibitors. Asuitable three-featured pharmacophore model comprising one H-bond acceptor and two H-bond donorfeatures (ADD.10) has been found to be the best QSAR model (Figure 1). An external library ofcompounds (~ 3000 molecules), pre-filtered using Lipinski’s rule of five, has been furtherscreened using the pharmacophore model ADD.10. By analyzing the fitness of the hits with respect tothe pharmacophore model and their binding interaction inside the urease active site, four moleculeshave been identified as extremely good urease inhibitors. Two of these have significant potentialand should be taken up for further drug designing process.

Ms Anamika GusainImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : H.N.B.G.U.

Designation : Ph. D. Scholar

Conjugated molecules are of great importance because of their role in chemistry, biology, medicines,as well as in many industrial applications. In context to these, we have synthesized four thiophenebased conjugated molecules [ e.g. 2-(4-nitrophenylethenyl-E)-thiophene (1),2-(4-hydroxyphenylethenyl-E)-thiophene (2), 2-(4-aminophenylethenyl-E)-thiophene (3) and2-(4-N,N-dibutylaminophenylethenyl-E)-thiophene (4) ] and studied their absorption, fluorescence,excited state and biological properties using solvatochromism method. Compounds 1 and 3 show redshifted absorption and fluorescence properties in solvent of varying polarity. Compound 2 showssignificant antioxidant activity as compared to other compounds. In addition that DFT studies alongwith ground and excited state parameters were used to explain the mechanism for some of the abovementions aspect.

Mr DEBASISH PALImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IISER-

KOLKATADesignation : Ph.D research

scholar (CSIR-SRF)

E. coli is a gram negative bacterium. O-antigens associated with the LPS of E. coli are stronglyimplicated in bacterial pathogenesis. E. coli O132 is recognized as a notorious gastrointestinalpathogen affecting humans and also reported to cause urinary tract infection, children under the ageof three. Recently in 2016, Knirel et al. reported the O-polysaccharide of serotype E. coli O132that consists of a pentasaccharide repeating unit . We have synthesized this pentasacchariderepeating unit as its aminoethyl glycoside without hampering the stereochemistry so that furtherglycoconjugate with protein can be done. The presence of ?-linked glucopyranose and ?-linkedgalactofuranose residue make the total synthesis of this pentasaccharide challenging.Retrosynthetic analysis suggested that the synthesis of the target structure could best be achievedthrough a block (3+2) synthesis. Judicious protecting group manipulations and remote participationmediated stereo-selective glycosylation done by NIS and TMSOTf is the key for this oligosaccharidesynthesis. Finally this structure has the potential to be immobilized on carrier protein and beevaluated for its immunogenic character for potential carbohydrate based vaccine design.

Dr ANITHA VENKATASAMYImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Sri G.V.G

Visalakshi College for WomenDesignation : ASSISTANT

PROFESSOR

Nickel Copper L-phenylalanine perchloric acid Metal Organic Frameworked (NCPP –MOF ) wassynthesized by taking equimolar ratio (1:1:1:1) of nickel chloride, copper sulphate, L-phenylalanineand perchloric acid by slow evaporation technique. Optically good quality NCPP crystal of moderatesize 9?mm?×?4?mm?×?2?mm was harvested over the period of 35?days. The functional groups presencesin the crystallized NCPP sample were identified by Fourier Transform Infrared (FTIR) spectroscopy.Single crystal X-ray diffraction study reveals that the NCPP crystal belongs to tetragonal crystalsystem with noncentrosymmetric space group C4h. UV–vis-NIR spectrophotometer study shows thecut-off wavelength of the grown samples as 262?nm and the optical band gap (Eg?=?4.38?eV) wascalculated for NCPP crystal. SHG efficiency of NCPP is found to be 1.14 times than that of standardpotassium dihydrogen phosphate (KDP). The work hardening coefficient (n?=?0.5) of NCPP crystalconfirming that the grown NCPP crystal belongs to hard category. The mechanical properties,Stiffness constant (C11), Yield Strength (?y), Fracture toughness (Kc), Brittleness index (Bi),Tensile Strength (T) and Yield Point (Y) are calculated and the corresponding graphs were plotted.The dielectric constant and dielectric loss of grown NCPP crystal have been studied. The nonlinearrefractive index values (?2) of the compounds vary in the range of -1.20 x 10-18 to -3.42 x 10-18m2/W. Their hyperpolarizability values (g) are determined as 2.01x10-35, 1.13 x 10-34, 2.09 x 10-34esu for phenylalanine and its MOF, respectively, indicating that metal chelating did lead toconsiderable enhancement in the third-order optical nonlinearities.

Dr UPASANA ISSARImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Kirori Mal College, University of DelhiDesignation : Assistant

Professor

DNA is the most sought after drug design target in the league of anticancer drugs. Drugs interferewith the replication and transcription of DNA, thereby causing cell death. Hoechst 33258 is aprominent minor groove binder that displays specific binding towards the adenine-thymine (AT) richregion of the minor groove of B-DNA (Teng et al., 1988). Molecular modeling studies have beencarried out in order to completely understand the iinteraction of various rotameric, tautomeric andionization states of Hoechst 33258 (existing at physiological pH) with the Dickerson-Drew dodecamerd(CGCGAATTCGCG)2 sequence. The electrostatic and hydrogen bonded interactions (Fig. 1) are found tobe the major forces responsible for the Hoechst-DNA complexation. QM/MM studies reveal importantgeometrical and energetic aspects of minor groove binding. The high complexation energy (-549.67kcal mol-1) signifies that a stable complex is formed between Hoechst and DNA. As a result of ourstudy, the binding of Hoechst 33258 to the Dickerson–Drew sequence can be better understood andthe results presented may be used in designing of novel DNA binding drugs with useful biologicalapplications.

Dr Garima TripathiImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : TNB College,

TMBUDesignation : Assistant

Professor

Peptide derivatives have always been attractive scaffolds in the area of the drug discovery due toits similarity with the target sites which most commonly are enzymes. Several peptides basedanti-cancerous drugs such as degarelix, mifamurtide etc. are available in the market. The majorshortcomings which have hindered the wide utility of peptides as drugs are their bioavailability andbio-stability. Peptidomimetics have emerged as a stable alternative with wide stability and broadapplicability. In an attempt to develop such novel peptidomimetic, crown ether tetheredpeptidomimetics were developed and their pharmacological applications were explored. Crown etherderivatives have exhibited broad utility in different areas such as phase-transfer catalysis,metal-crown complexes etc. The work presented herein will disclose the discovery of crown ethertethered dipeptide, peptidomimetics and study of benzo-12-crown-4 containing dipeptide as novelanti-cancerous agent which have exhibited selective apoptotic activities against germ cells. Thepresent study revealed the production of H2O2 induced by dipeptide in dose dependent manner whichled to cell cycle arrest at M-II stage in lower concentration and apoptosis followed by degenerationin higher dosage. The increased level of H2O2 was associated with increased cytosolic cytochrome clevel. The increased cytosolic cytochrome increased caspase-3 activity and DNA fragmentation intreated eggs that had morphological apoptotic features. Therefore, dipeptide used in the presentstudy has shown a potential to induce cell cycle arrest and apoptosis through the generation of H2O2and mitochondria- mediated pathway in rat eggs cultured in vitro. This apoptosis inducing ability ofthis crown containing peptide indicates that it can be used as a potential candidate for thedevelopment of potential anticancerous drugs. The potential anti-cancerous activity of the crownether containing peptide was also investigated by studying their effect on breast cancer cell line,MDA-MB-231. The ROS, MTT assay and other such parameters studied revealed the potentialanti-canceorus properties of the crown ether containing peptide. Overall these studies indicate thatwith appropriate functionalization and modification in the amino acid sequences, the crown etherpeptides could be developed as novel anti-cancerous drug.

Dr Sudipta MondalImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : NIT Durgapur


The native, folded state was once considered to represent the global energy minimum of a givenprotein sequence. More recently, the discovery of the cross-? amyloid state revealed that deeperenergy minima exist, often associated with pathogenic, fibrillar deposits and implicated for manydiseases such as Alzheimer’s, Parkinson’s, and type II diabetes. Fortunately, a sizable energybarrier impedes conversion from native to pathogenic states; however, little is known about thestructure of this transition state. In this study, we present the first evidence of the conversionof metastable cross-?-helical crystals to thermodynamically-stable cross-?-sheet-like fibrils by ade novo designed heptapeptide. A multitude of experimental techniques such as conventional X-raycrystallography, microcrystal diffraction, real-time WAXS analysis were employed to decipher themetastable nature of the cross-? crystal and thermodynamically stable state of cross-? fibrils.Furthermore, for the first time, we demonstrate at atomic resolution that the flip of a peptideplane from a type I to a type II' turn facilitates transformation to cross-?-structure and assemblyof a dry steric-zipper. This is also supported by real-time optical microscopy analysis whichrevealed the sequential transformation of the monomer to cross-? crystal to cross-? fibrils. Suchsequential structural transition is the hallmark of amyloid fibril formation by many native proteinsequences. Thus, this study establishes the potential of peptide turn, a common protein secondarystructure, to serve as a principal gatekeeper between native metastable folded state and the amyloidstate.

Mr SUMANTA PRADHANImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : CSIR-

NATIONAL CHEMICAL LABORATORY, PUNE

Designation : SRF

A novel AuNi-SBA-15 catalyst, has been synthesized, and the conversion of furfural to cyclopentanoneat milder temperature and pressure conditions has been reported. The reaction was carried out at 1400C and 20 bar H2 in an aqueous medium. The surface morphology and composition of the catalysts werethoroughly studied by XPS, insitu DRIFTS, H2 TPR, ME-AES, and TEM characterizations. The XPS and CODRIFT experiments confirmed that there is an intimate mixing of AuNi through alloy formation. TheEDX elemental mapping confirmed the high distribution of AuNi alloy nanoparticles. The size of thenanoparticle was below 10 nm, as revealed by HR-TEM images. The monometallic Ni5-SBA-15 andAu2.5-SBA-15 catalyst gave merely 47 and 13 % furfural conversion. However, the bimetallic catalysts(Au0.25Ni2.5-SBA-15) gave superior catalytic activity compared to the monometallic catalyst with 99% furfural conversion and 86 % cyclopentanone selectivity showing the synergistic effects in thecombination

Mr Aravind KrishnanImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Saint Berchmans College

Designation : Assistant Professor in Chemistry

DNA sequencing is one of the major areas in which active research is being carried out. Graphene has been used as an effective molecule for the same using nucelosides. In the present work, we have analysed the use of Boron and Aluminium substituted graphene for dna sequencing applications. The structures of graphene, B and Al substituted graphene’s were generated using gauss view software and its interaction studies (using molecular mechanics and quantum mechanics) with the four nucleotides ie deoxyadenosine monophosphate (nucleotide with adenine) A1, deoxycytidine monophosphate (nucleotide with cytosine) C1, deoxygunosine monophosphate (nucleotide with guanine) G1, deoxythymidine monophosphate (nucleotide with thymine) T1 were carried out. Further, Monte Carlo simulations were carried out to find out the minimum potential required for the release of nucleotide from the graphene’s used for the study. We conclude that B-Graphene is a better candidate in dna sequencing compared to Graphene.

Dr Reshu SananImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : I K Gujral

Punjab Technical University, Kapurthala


The remarkable ability of surfactants to influence the properties of surfaces or interfaces and toorientate themselves into structures called micelles, lends them a wide range of surface functionsviz. wetting, emulsifying, solubilising, foaming/defoaming, rheology-modifying, antistatic,glossing, lubricity and surface conditioning etc. endowing them with ubiquitious deployment invarious industrial processes and products.1 Surfactants may be applied to advantage in theproduction and processing of foods, agrochemicals, pharmaceuticals, personal care and laundryproducts, petroleum, mineral ores, fuel additives and lubricants, paints, coatings and adhesives,and in photographic films. Thus monitoring the change in the concentration of the surfactant or itsestimation in a dilute solution under equilibrium condition is a matter of great concern for bothchemists and analysts. Ion selective membranes provide a good substitute for this problem beinginexpensive, allowing simple and straight forward operation, providing rapid responses and capableof being incorporated into a multi sensor array2,3. Thus, with an aim to determine the concentrationof surfactant in a particular product, a new potentiometric PVC sensor (membrane) based on neutralion-pair complexes of dodecylmethylimidazolium bromide-sodium dodecylsulfate (C12mim+DS-) andbis(2-ethyl-hexyl) phthalate (DOP) as plasticizer has been developed. The membrane fitted electrodewas utilized to determine cetylpyridinium chloride (CPC), tetradecyltrimethylammonium bromide (TTAB)and benzalkonium chloride (BC) in commercial products. It had a response time of 5 seconds, a lifetime of more than 120days and there was no interference from inorganic ions such as K+, Ca2+, Mg2+,Zn2+ and Al3+. The reliability of the proposed electrode was also examined statistically incomparison with that of classical two phase titration method.

Ms PADMINI GUPTAImage Delegate ID Theme Details


Research


OF DELHIDesignation : Ph.D.

RESEARCH SCHOLAR

Abstract: In the present work, the successfully synthesis of magnetic graphene oxide with the immobilize iron oxide nanoparticles on the surface of graphene oxide sheet. Further, the addition of aminopropyltrimethoxysilane (APTMS) on the magnetic graphene oxide (MGO). Finally, we found the amine-functionalized magnetic graphene oxide (MGO-NH2) as a heterogeneous nanocatalyst. The synthesized heterogeneous Nanocatalyst were characterized by various techniques such as FTIR, TGA, XRD, TEM, VSM, SEM and EDX analysis. The developed nanocatalyst (MGO-NH2) was used as an efficient heterogeneous catalyst for the nucleophilic ring opening of epoxides with derivatives of amines under green solvent at lesser reaction time. The present catalyst have best activity, higher regioselectivity, excellent yields and reused for up to seven runs without any considerable loss in its catalytic activity. Due to the ferromagnetic nature of Fe3O4, the prepared composite material could be easily recovered after completion of the reaction through an external magnetic force. It shows the functions of both acidic and basic groups due to the carboxylic groups present on the sheet edges and amine groups immobilized on the surface of GO respectively. References 1. Rostamizadeh, S.; Hemmasi, A.; Zekri, N. Nanochem Res, 2017; 2(1): 29-41. 2. Mondal, J.; Nguyen, K.T.; Jana, A.; Kurniawan, K.; Borah, P.; Zhao, Y.; Bhaumik, A. Chem. Commun., 2014, 50, 12095. 3. Saptal, V.B.; Sasaki, T.; Harada, K.; Nishio-Hamane, D.; Bhanage, B.M. ChemSusChem, 2016, 9, 644 – 650.

Mr Rohit Singh SajwanImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : ChemistryDesignation : Research

Scholar

Radon is radioactive gas that occurs as an intermediate product of Uranium-238 decay series, which is formed by alpha decay from Radium. Uranium occurs in all types of rock and soil. Radon concentration varies with not only on Uranium contents but also on lithology of area. Radon reaches the atmosphere by exhalation process. Exhalation rate is highly affected by geology and presence of thrust. Radiation hazard strongly depends on radon exhalation rate from soil. The Samples were collected from Pauri Garhwal and Tehri Garhwal District of Uttarakhand. The measurement is carried out by using Active method throughout SMART Rn-Duo. In this report we compared Mass Exhalation rate of soil in different geological conditions. The mass exhalation rate in soil samples of Tehri Garhwal were found be very high. The mass exhalation rate in Pauri District varies from 6.63±2.24 mBq/Kg/h to 65.96±3.32 mBq/Kg/h and in Tehri District varies from 26.39±6.55 mBq/Kg/h to 208.06±10.05 mBq/Kg/h. The details of the results obtained from this study will be discussed during conference. Key Word:- Radon, Uranium, Radium, Lithology, Thrust, Mass exhalation,

Mr Ashique Al HoqueImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Jadavpur

UniversityDesignation : DST Inspire

Fellow (SRF)

Abstract

Prostate cancer is the second most common cancer in men behind lung cancer. Site specific Targeting to the cancer cells is now very essential to overcome the toxicity related issues caused to our body. The aim of the current study is to develop and characterize PLGA nanoparticles (NPs) containing an anticancer agent, tagged with a suitable ligand (monoclonal antibody) for targeted delivery of the drug. Nanoparticles were prepared by a conventional method called multiple emulsion solvent evaporation method. Drug-excipients interaction, surface morphology, zeta potential and size distribution, cellular uptake were carried out using Fourier transform infrared spectroscopy (FTIR), Field emission scanning electron microscopy (FESEM), Zeta sizer Nano ZS90, particle size analyzer and confocal microscopy respectively. No chemical interaction was observed between the drug and the selected excipients. NPs had a smooth surface, and a nanosize range (250–380 nm) with a negative surface charge. Drug loadings of the prepared particles were 1.5%±0.02% weight/weight (w/w), 2.68%±0.5% w/w, 4.09%±0.2% w/w, 8.50%±0.58% w/w for NP1–NP4, respectively which were prepared varying the drug and polymer ratios. A sustained drug release pattern was observed from the nanoparticles in vitro and they were internalized well in the PC3, LnCap, cancer cells on a concentration dependent manner. Drug loaded nanoparticles were found to be more cytotoxic than the free drug and the cellular internalization was observed in PC3, LnCap cancer cells in vitro. Further the prepared nanoparticles will be conjugated with suitable ligand for the site specific targeting to the prostate cancer cells in vivo. Thus the formulation might be suitable for the effective treatment of prostate cancer.

• Keywords: PLGA Nanoparticles; Prostate Cancer; Anti-PSMA antibody.

References:

1. DeGrendele H, Jain VK. The anti-HER2 monoclonal antibody pertuzumab may be effective in androgen-independent prostate cancer. Clinical prostate cancer. 2003; 2(3):143-5. 2. Yan J, Wang Y, Zhang X, Liu S, Tian C, Wang H. Targeted nanomedicine for prostate cancer therapy: docetaxel and curcumin co-encapsulated lipid–polymer hybrid nanoparticles for the enhanced anti-tumor activity in vitro and in vivo. Drug delivery. 2016; 23(5):1757-62. 3. Cheng J, Teply BA, Sherifi I, Sung J, Luther G, Gu FX, Levy-Nissenbaum E, Radovic-Moreno AF, Langer R, Farokhzad OC. Formulation of functionalized PLGA–PEG nanoparticles for in vivo targeted drug delivery. Biomaterials. 2007; 28(5):869-76. 4. Sinha B, Mukherjee B, Pattnaik G. Poly-lactide-co-glycolide nanoparticles containing voriconazole for pulmonary delivery: in vitro and in vivo study. Nanomedicine. 2013; 9(1):94–104.

Dr Suprakash RoyImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : HMSM Govt.

PolytechnicDesignation : Sr. Lecturer

The cyclization of 2-Iodobenzamides to thiocyanate ion is one of the most expedient and facile synthetic routes to mesoionic indazol-3-one derivative. Here a novel regioselective Cu(I)-catalyzed, intramolecular cross-coupling reaction of thiocyanate ion to benzamide on solid support with fully compatible microwave-assisted indazol-3-one synthesis is reported. The final products were characterized by FTIR, 1HNMR, EPR and ESI-mass spectra. The physicochemical studies are significant to yield structural information on the mesoionic nature. Compounds (2a-2g) emits at 490-500nm, with quantum yield estimated as 0.20-0.23, upon excitation at 310nm.

Mr Sambit RoyImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Indian Institute of Technology

KharagpurDesignation : Ph.D student

Abstract: Polyelectrolyte membrane fuel cell (PEMFC) could be an efficient alternative to the fossil fuels due to long-term chemical stability and thermal stability along high dimensional and mechanical properties in addition to low cost and high efficiency. Proton exchange membrane is considered the vital constituent of the PEMFC. The current state of the art proton conducting polymers are Nafion®, Flemion®, Aquivion® and Hyflon® which are all perfluorinated copolymers. Their fluorinated structure causes high expense and environmentally hazards. So, development of alternative nonfluoinated polymer membrane is essential which would be efficient as well as low cost. The click polymerisation reaction between the terminal azide and alkyne has been utilized here to create the backbone of the copolymers.

A new series of flexible sulfonated polytriazoles (PTEOSH-XX) were synthesized successfully by using a bisalkyne and a mixture of two diazide monomers with varying molar ratios. The formation of the copolymers were characterized using FTIR and NMR spectroscopic techniques. These copolymers showed excellent solubility in different organic solvents and high thermal stability with 10% decomposition temperature (Td,10) in the range 231-244 °C. In addition to that, the copolymers also exhibited moderate water uptake, good dimensional stability and excellent stress-strain properties. The membranes showed tensile strength, Young’s modulus and elongation at break values in the range of 64-42 MPa, 2.19-1.01 GPa, 29%-27% respectively. The theoretical ion exchange capacity (IEC) values of the polymers were in the range of 2.85-3.39 mequiv/g. The TEM micrographs showed hydrophilic-hydrophobic phase separated morphology along with very fine ionic clusters. The polymers exhibited very high proton conductivity values up to 217 mS cm-1 at 90 °C. Activation energy values were found to be in the range of 13.06-13.62 kJ mol-1. These results suggest that PTEOSH-XX membranes could be useful for practical application in PEMFC.

Mr Ayon KarmakarImage Delegate ID Theme Details


Research



Recent studies have shown that electrochemically generated high purity hydrogen through cathodichydrogen evolution reaction (HER) by means of water electrolysis in alkaline medium could beconsidered as one of the most cost-effective, sustainable and industrially accepted method. However,the efficiency of hydrogen production is affected by the high overpotential of HER. To address thisissue, design and fabrication of low-cost, effective and durable electrocatalysts become mandatory.In this context, we carried out one-step in situ fabrication of nickel vanadate nanoparticlesanchored N-doped reduced graphene oxide hybrids (Ni3V2O8/NRGO) consisting varying NRGO content byreflux method. Subsequently, the electrocatalytic HER activity of Ni3V2O8/NRGO hybrids wereinvestigated in an alkaline medium (1.0 M KOH). The effect of NRGO content in product morphology,distribution of Ni3V2O8 nanoparticles on NRGO sheets and HER performance of these hybrids was alsostudied. It was noted that addition of NRGO in hybrid resulted in faster electron transfer asindicated by remarkable reduction in charge transfer resistance (~1.6 ?) compared to bare Ni3V2O8(~57.1 ?). Our findings showed that electrocatalytic activity of the optimised Ni3V2O8/NRGO (5.6wt.%) hybrid on par with Pt/C for HER in 1.0 M KOH. Further, high electrochemical active surfacearea facilitates this hybrid material to achieve very low overpotential, small Tafel slope, and highexchange current density. In addition, it demonstrated superior long-term and accelerated stabilitycompared to that of the benchmark Pt/C in a strong alkaline medium. These findings clearly indicatedthe role of Ni3V2O8/NRGO (5.6 wt%) hybrid as a promising and durable cathode-catalyst forelectrochemical water splitting.

Mr Karthik KumarImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : G.T.N. Arts

College, DindigulDesignation : Research

Scholar

Chitosan is widely applied in biomedical and cosmetic fields. For this reason, there is a need tomodify this biopolymer to achieve new properties of chitosan-based materials. The properties ofchitosan can be modified by several cross-linking methods. In this work, we used the chemicalcross-linking of chitosan with Sebacic acid, after which cross-linked chitosan was shaped into a 3Dstructure by the lyophilisation process. For the material obtained, FTIR analysis was performed tocharacterise the structure of cross-linked chitosan. The results show that several properties ofchitosan can be changed after cross-linking by Sebacic acid. The positions of bands in the FTIRspectra of chitosan were shifted after cross-linking. SEM and AFM reveals that the smoothness ofcross-linked chitosan. This method of cross-linking can be useful for obtaining materials withspecific properties.

Mr Sopan PatilImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : SNJB's K.K.H.A. Arts, S.M.G.L. Commerce & S.P.H.J.

Science College, ChandwadDesignation : Research

Fellow

This paper demonstrates the synthesis of SnO2 nanoparticles using a simple hydrothermal route in the presence of the surfactant hydrazine at 100 °C for 12h. X-ray diffraction (XRD), field emission scanning electron microscopy, and transmission electron microscopy (TEM) were employed to characterize the as-prepared product, and optical property was studied by UV-visible diffuse reflectance spectroscopy (DRS). The XRD pattern of the as-prepared sample is indexed to the tetragonal structure of SnO2, and the calculated particle size is 22.4nm, which is further confirmed by TEM. The selected area electron diffraction patterns showed continuous ring patterns without any additional diffraction spots and rings of secondary phases, revealing their crystalline structure. Analysis of the DRS spectrum showed the bandgap of the synthesized SnO2 to be 3.6eV. The anionic surfactant hydrazine plays a key role in the formation of the SnO2 nanostructures. A probable reaction for the formation of SnO2 nanoparticles is proposed. Keywords: SnO2 nanoparticles Hydrothermal route FESEM TEM

Mr Anil GiteImage Delegate ID Theme Details


Research


Science College, ChandwadDesignation : Assistant

Professor

Simple and cost-effective route for the synthesis of lead telluride powder and films is reported in studies. The PbTe powder is synthesized by a chemical bath technique at room temperature and environmental pressure with conventional chemicals as starting precursor materials. The average grain size of the powder particle collected at the bottom of the bath for different duration is different and at 288 hours the synthesized yield of PbTe powder is maximum, 0.71 g and for as duration increases the yield decreases. X-ray diffraction, Scanning electron Microscopy (SEM) and Fourier transform analysis of all samples gives the formation of dense, smooth, and uniform with silver gray metallic luster lead telluride crystals. The film exhibits p-type conduction and has a moderate Seebeck coefficient of 0.149 V/K and low electrical conductivity of 0.019 S/cm. The formation mechanism of the lead telluride powder and films is proposed in the present research work. Keywords: PbTe powder, XRD, SEM, FTIR, Seebeck coefficient, electrical conductivity etc.,

Dr Amit MannaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Vidyasagar

UniversityDesignation : Post Doctoral

Researcher

In last few decades, energy crisis has drawn considerable attention to the researchers for finding sustainable alternate sources of energy[1-2] . Among the different renewable sources of energy, solar energy is considered to be a reliable one to confront the energy crisis. A cost effective chemical reduction route was followed to grow CdSe nanoparticles. Fabricating the n-CdSe/p-Si heterojunction solar cell, a detail study was made on it to calculate its open circuit voltage (Voc), short circuit current density (Jsc), maximum power (P), fill factor and efficiency (?). 1. Abbasi, T.; Premalatha, M.; Abbasi, S.;. Renewable and Sustainable Energy Reviews. 2011,15, 891-900. 2. Kaygusuz, K.; Renewable and Sustainable Energy Reviews. 2012, 16, 1116-1124.

Dr Bibekananda NayakImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Fakir Mohan


Professor

Black hole is a region in space-time, where, gravitational field is so strong that even lightcan’t escape from it. In the usual formation scenarios, the typical mass of a black hole at theformation could be as large as the mass contained in the Hubble volume. Black holes can thus spanenormous mass range. The formation masses of some of the black holes could be small enough to haveevaporated completely by the present epoch due to Hawking evaporation. Early evaporating black holescould account for baryogenesis in the universe. On the other hand, presently surviving black holescould act as seeds for structure formation and could also form a significant component of darkmatter. Once formed, these black holes obey both Hawking evaporation and accretion: absorption ofenergy matter from the surroundings. In this work, we study the evolution of black holes in aninteracting dark energy model, where we consider that dark energy interacts with matter and one maygrow at the expense of other during the evolution of the Universe. Our assumed interacting modelsuccessfully explains the observed accelerated expansion of the Universe and softens coincidenceproblem. From our study, we found that in radiation dominated era black hole mass is increased dueto accretion of radiation but not affected by interacting dark energy. Whereas in matter dominatedera, accretion of radiation is ineffective but black hole mass changes due to the presence ofinteracting dark energy and hence black hole will live longer. Black holes thus can be treated as apotential candidate for dark matter.

Mr GAURAV GUPTAImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : DEPARTMENT OF

PHYSICS AND ASTROPHYSICS,UNIVERSITY OF DELHI


Microstructural analysis of Mg-doped ZnO nanostructures by Rietveld Refinement Method

Gaurav Gupta1, Shyama Rath1* 1Department of Physics and Astrophysics, University of Delhi, Delhi-110007

1Author: [email protected]

Abstract: Ternary ZnO-based alloys promote bandgap engineering and heterojunctions design with the purpose of tuning their bandgap in the range of blue-green and ultraviolet wavelength. Alloying ZnO with metals like Mg in place of Zn, bandgap is tuned up to 3.99 eV for 34 mol% of Mg content. Alloying MgO with ZnO is seriously limited by their structure mismatch, for ZnO crystallizes in the wurtzite structure compared to the rocksalt structure of MgO crystals. Crystal structure difference leads to phase separation after certain Mg content. Due to nearly equal ionic radii of Mg2+ (0.57 Å) and Zn2+ (0.60 Å) ions,wide range of solubility of Mg content is expected. But in terms of the phase diagram of ZnO–MgO binary system, the thermodynamic solid solubility is less than 4 mol %. To achieve the high solubility limit, Solid-state reaction method is employed to synthesize nanocrystalline Zn1-xMgxO alloy powder and solubility limit is achieved up to 10 mol % [1].Pure single wurtzite phase formation is confirmed by X-ray diffraction and Rietveld refinement [2] upto 10 mol%.Structural parameters i.e decrease in parameters a, c, crystallite size with contraction in volume is observed. Increase of strain in the lattice is observed by decrease in Zn-O bond length, increase in bond angle with distortion calculated by BVS method [3].Further, hardness of the material is much affected and a decrease in hardness is observed with an increase in the oxidation state of cation and anion.

References: 1. S. Gowrishankar, L. Balakrishnan, and N. Gopalakrishnan, Ceramics International 40, 2135 (2014). 2. P. Thompson, D.E. Cox, and J.B. Hastings, Journal of Applied Crystallography 20, 79 (1987). 3. I.D. Brown, Chemical Reviews 109, 6858 (2009).

Dr PARVEJHA MALDARImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Shivaji

university kolhapurDesignation : RESEARCH

SCHOLAR

Cu2CoSnS4 (CCTS) thin films have been prepared by spray pyrolysis technique at substrate temperatureof 350 ºC with methanol as a solvent. The thiourea concentration has been varied from 0.3 M to 0.9M with an interval of 0.2 M. XRD analysis depicted stannite structure of the films. The phase purityof CCTS thin films has been evaluated by Raman analysis. The surface morphology study revealeddrastic variation in the morphology of the films with respect to change in thiourea concentration.The EDAX analysis showed the presence of constituent elements like Cu, Co, Sn and S in the depositedthin films. The energy band gap values for the CCTS thin films were found over the range 1.51 eV -1.55 eV. The static contact angle measurement of the CCTS films with Na2SO4 electrolyte revealedhydrophilic nature of the films. To study the photoactive nature of the CCTS thin filmsphotoelectrochemical solar cell (PEC) has been constructed using sodium sulphate as electrolyte, andplatinum as a counter electrode. The PEC cell based on CCTS thin films as working electrodes, whichwere deposited with 0.7 M thiourea concentration showed power conversion efficiency of 2.33 %.

Mr Karthik RImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : National

Institute of technology Andhra Pradesh

Designation : Btech final year student

A STUDY ON MICRO WELD FORMATION IN METALLIC POWDERS USING RADIO WAVES Karthik R* Department of Metallurgical and materials Engineering, National Institute of Technology Andhra Pradesh, Tadepalligudem 534102, Andhra Pradesh Email ID: [email protected] Abstract: The discovery of radio waves had made a big revolution in telecommunication field by the very beginning of the nineteenth century. Almost many equipment were controlled wirelessly using radio waves. More efficient antennas increased the efficiency of transmitting and receiving radio waves around the globe. Thus radio waves only served in wireless communication systems .In the present paper I have proposed a different application of radio waves. Radio waves of particular frequencies can cause a temporary weld in metallic powders. An experiment was carried out to study the micro weld formation of metallic powders. Fine powdered samples of Ni, Cu, Fe, Ag, and Cr were radiated using a radio frequency generator. The samples were observed under a microscope. It was observed that the metal powders were clinging together. Each powder sample had a unique frequency response. Fe and Ag showed good response in the high frequency region where as Cr and Ni in the very high frequency regions. Later the experiment was done after mixing the powders in particular ratios .In this case the phenomenon was observed in various frequency regions. Observation shows that a micro weld formed due to irradiation by radio waves might have caused a fatigue to the metal powders that made them cling to each other. The application of this phenomenon maybe employed in recovery of damaged material components in artificial satellites. Development of Radio wave guided materials in which we will use radio waves to guide the material to form a weld in that particular region. References:[1] Phillips V J 1980 Early Radio Wave Detectors (London: Peregrinusand the Science Museum)

Mr KIRAN TImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Central University of Tamil NaduDesignation : Research

student (PhD)

Shortcuts To Adiabaticity (STA) protocols are nonadiabatic processes that reproduce in finite time the same initial and final states as that of an infinitely slow adiabatic process1. These protocols can be used as an alternate driving of the system to implement the adiabatic process. We investigate the single spin quantum systems using various different methods of STA and design quantum engines with spin quantum systems as a working medium to study its characteristics including cost of implementation. Comparing different methods such as Counter-Diabatic (CD) driving2, Invariant based Inverse Engineering Method3 and Local Counter-Diabatic4 Methods will help us to determine efficient method with less cost of implementation. This study will also discuss the adiabaticity factor and work obtained from each of the above methods for differentiating their merits and demerits for the purpose of quantum engines.

References: 1. Erik Torrontegui, Sara Ib_a~nez, So_a Mart__nez-Garaot, Michele Modugno, Adolfo del Campo, David Gu_ery- Odelin, Andreas Ruschhaupt, Xi Chen, J. G. Muga. Advances in atomic, molecular and optical physics 62, 2013 117169. 2. Adolfo del Campo Phys. Rev. Lett. 111, 2013 100502. 3. H. R. Lewis and W. B. Riesenfeld J. Math. Phys. 10, 1969 1458. 4. Adolfo del Campo and Kihwan Kim New J. Phys. 21, 2019 050201.

Ms RITUPARNA MAJIImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Central University of Karnataka,

Karnataka.Designation : Student(M.Sc

2nd year in Physics)

Quantum algorithm, as compared to classical algorithm, plays a notable role in solving linearsystems of equations with an exponential speedup. Here, we demonstrate a method for solvingaparticular system of equations by using the concept of well-known Grover’s quantum searchalgo-rithm. The algorithm finds the solution by rotating the initial state vector in the Hilbertspace toget the target solution state. It mainly involves finding particular matrices that solve the set ofequations and constructing corresponding quantum circuits using the basicquantum gates. We ex-plicitly illustrate the whole process by taking 48 different set of equationsand solving them by usingthe concept of Grover’s algorithm. We propose new quantum circuits foreach set of equations anddesign those on the IBM quantum simulator. We run the quantum circuit forone set of equationsand obtain the desired results, and hence verify the working of the algorithm.

Dr PURUSHOTTAM BHAWREImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Barkatullah

University BhopalDesignation : Guest Faculty

Teacher

The conduct of polar ionosphere is altogether not quite the same as the tropical and low scopeionosphere it is because of overwhelmed by high geomagnetic action and gets a completely uniqueradiation spending plan. The behavior of Total Electron Content and Amplitude Scintillation Indexhas been studied over the Indian polar stations Himadari (78.9°N Lat. and 11.9°E Long.) and Maitri(70.650 N Lat, 11.450E Long) during the low solar activity period, January to December, 2008. Theoutcomes are introduced here, for the Arctic station the study has been performed only for the monthof October and November due to non-availability of data for other months, while for Antarcticstation, the study has been carried out monthly as well as seasonally. From the analysis we observedthat TEC achieves its highest values during the months of January and December as compared to Junemonth in contrast to equatorial or low latitude TEC, because during these months (Polar days) thepolar cap receives the solar radiation round the clock, in the month of June lowest value of TEC wasrecorded due to absence of solar radiation during this month (Polar night). The seasonal studyshowed that during the winter season the values of TEC remain low due to low ionization and duringsummer season the values of TEC achieve the highest values which are contrary to equatorial and lowlatitude ionosphere. The high latitude L-band scintillation were also studied during this period2008. The observations reveal that the high latitude L-band scintillations were generally weak type(S4 index less than 0.5) since this period experienced low solar activity conditions. Season wise,their maximum percentage occurrence is observed in winter season i.e. polar night periods from Mayto August 2008 as compared to summer and equinox seasons.

Mr SURAJ KUMAR PATIImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : FAKIR MOHAN UNIVERSITY, BALASORE, ODISHA

Designation : RESEARCH FELLOW

From Various cosmological observations, it was found that the universe is expanding with anaccelerating rate. But standard model of cosmology fails to explain this observational fact. Toovercome this situation, in theoretical cosmology, generally two ways have been used. First one isby introducing a new kind of energy having negative pressure termed as dark energy and the secondone is by modifying the theory of gravity. Among different types of modified theories of gravity, inthis work, we use metric F(R) gravity obeying Starobinsky model for explaining the presentaccelerated expansion of the universe. The reason behind choosing Starobinsky model is that it couldexplain the inflationary scenario of early Universe. First, we calculate the field equation forF(R) gravity and then we derive the expression for scale factor. Finally, we show the acceleratedexpansion of the universe by calculating the deceleration parameter. Our result shows that for earlyperiod of evolution, the expansion of the universe was decelerated one. But today it is acceleratedone and our analysis predicts that it continues to expand in the accelerating rate forever.

Mr Kisan KhatriImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Central

Department of Physics, TUDesignation : Physics

student

This research presents the study of Global Solar Radiation (GSR) of Pokhara (Lat. 28.19994°N, Long. 83.9784° E) Airport. Pokhara is a Metropolitan city situated at western part of Nepal which is about 200 km west of Kathmandu, the capital city of Nepal. This city is about 800 m above from the sea level and lying just 35 km south of the Machhapuchhre Himal. This paper explains about the daily, monthly and seasonal variation of global solar radiation and also compared it with different meteorological parameters like sunshine hour, relative humidity, rainfall, temperature and wind speed. The GSR is estimated at the horizontal surface using data of GSR of the year 2016 A.D. of Pokhara Airport which was measured by CMP6 Pyrometer and meteorological parameters on Angstrom empirical model. The empirical constants for the year 2016 are obtained as, a =0.40 and b = 0.22. These empirical constants are used to predict the GSR for the year to come. The predicted values and measured values of GSR are used for the analysis of different errors using statistical tools like CRM, MBE, RMSE MPE and R 2 which are found to be 0.159, 0.160, 0.323, 8.92% and 0.643 respectively. All the above values shows that there is good agreement between measured values and predicted values of GSR at Pokhara. The coefficient of determination 0.643 is found in between measured GSR and predicted GSR . The annual average daily global solar radiation is about 16.05 MJ/m^2/day which is sufficient to promote solar energy technology at sub-Himalaya terrain Pokhara and other similar geographical locations of Nepal. The finding empirical constants and meteorological parameters can be used to measure the GSR at Pokhara and other regions of Nepal having similar geographical location.

Keywords: Global solar radiation, meteorological parameters, empirical constants, statistical errors.

Ms Priya MajiImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : NIT Durgapur


Standard model is an well established theory till today. But recently there are lot of discrepanciesfound in various decay channels which could not be accommodated within the standard model (SM). Sowe need to go beyond SM. There are lot of new models which are being implemented currently to solvethe anomalies. Family non-universal Z' model, 2HDM, leptoquark are one of those well motivatedextensions of the SM. We will analyze various flavor observable of B meson decay modes and try tostudy phenomenological implication of new physics models on those observable. In this work we willshow the variation of different parameters of B decay channels with contribution of new physicscoming from new intermediate particles.

Dr Gaurav LoharImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Lal Bahadur

Shastri College of Arts, Science and Commerce,

SataraDesignation : Assistant

Professor

Synthesis of copper oxide reduced graphene oxide composite for flexible electrochemical supercapacitor G. M. Lohar Lal Bahadur Shastri College of Arts, Science and Commerce, Satara 415002 E-Mail: [email protected] Phone No. +91-9604695030 Abstract: The CuO/RGO composite based nanomaterials developed for electrochemical energy storage devices. The modified Hummers method engaged to develop graphene oxide and CuO/RGO composite is produced adopting a method of co-precipitation. The composite of CuO/RGO synthesized concerning different concentrations of CuO and RGO. The examined structural, morphological, electrochemical, and supercapacitance properties for CuO/RGO composite. The CuO/RGO shows the Nano-flex like nature. The electrochemical properties are investigated using electrochemical impedance spectroscopy. The cyclic voltammetry and charge-discharge study involved to investigate the supercapacitor behavior. Present work describes the development of cost-effective and high-performance CuO/RGO based nanomaterials for electrochemical energy storage devices. The CuO/RGO composite can be used as flexible supercapacitor devices. Keywords: Graphene, supercapacitor, nanomaterials Reference

[1] K. K. Purushothaman, B. Saravanakumar, I. M. Babu, B. Sethuraman, G. Muralidharan, Nanostructured CuO/reduced graphene oxide composite for hybrid supercapacitors, RSC Adv., 4, 2014, 23485-23491

Mr Milon MiahImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Indian

Association for the Cultivation of science


Fe-intercalated few layers reduced graphene oxide: A unique material for supercapacitor applications Milon Miah* and Shyamal K. Saha School of Materials Science Indian Association for the Cultivation of Science, Jadavpur, Kolkata-700032, India. *E-mail: [email protected] Abstract: Although intensive research has been carried out on composite materials containing transition metal (TM) oxides and graphene for supercapacitor application, the field remains totally unexplored to intercalate TM atoms in few layers reduced graphene oxide (rGO) to design high performance supercapacitors [1, 2]. The major advantages are the enhancement in porosity and formation of trap states at the Fe sites for better charge storage capacity. Therefore, in the present work Fe- intercalated few layers rGO samples (Fe_rGO) are synthesized to enhance the interlayer separation from 0.34 to ~1 nm. The enhancement of interlayer separation is characterized by x-ray diffraction which shows a single peak at 2? value of 8.70 indicating the layered type material with interlayer separation of 1 nm. Large enhancement in specific capacitance to about 896 F/g and high energy density of 31 Wh/kg are observed in this highly porous material. All these results of enhancement in specific capacitance and energy density are explained on the basis of trap states created at the Fe sites and large enhancement in porosity due to Fe intercalation. Cyclic stability to about 85% after 8000 cycles is also verified. Quantitative evaluation of trap states and modification of charge transport is observed. Due to trap centers, high value of dielectric permittivity is achieved. References: [1] C. Liu, Z. Yu, D. Neff, A. Zhamu, B. Z. Jang, Nano Lett. 2010, 10, 4863–4868. [2] M. Miah, S. Bhattacharya, A. Gupta, S. K. Saha, Electrochimica Acta 2016, 222, 709-716.

Mr Patitapaban SahooImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : N.I.T

JamshedpurDesignation : Ph.D

Our understanding of the physical processes is largely based on quantum theory of scattering. Incase of charged hadrons scattering there exist two potentials, one is nuclear in origin and other iselectromagnetic. To treat such problems exactly we replace the local nuclear interaction byseparable non-local one. To study both bound and scattering states exact analytical expression forthe electromagnetic distorted nuclear Jost function is constructed. As the Jost function has theability to reproduce bound states energies and scattering phase shifts, a closed form expression forthe same for motion in Hulthén modified Yamaguchhi potential. The alpha-Carbon and proton-Oxygensystems are studied to investigate the merit of the Jost function. Good agreement with experimentalresults is achieved.

Mr PRASHANT BABURAO KHARATImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Department of

Physics. Dr. Babasaheb Ambedkar Marathwada University, Aurangabad,

Pincode - 431 004Designation : Research

Student

Title: Magnetic Induction Heating of Oleic Acid-Coated Nickel Ferrite Nanoparticles for Magnetic Fluid Hyperthermia Authors: Prashant B. Kharat, Sandeep B. Somvanshi, Anant C. Nawle and K. M. Jadhav Author’s Affiliation: Department of Physics, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India - 431001 Corresponding author: [email protected] Abstract: Nickel ferrite (NiFe2O4) nanoparticles were synthesized by using a chemical co-precipitation technique. The synthesized NiFe2O4 nanoparticles were functionalized by the oleic acid. The structure, morphology, elemental composition and magnetization studies of NiFe2O4 and functionalized Nickel ferrite (OA-NiFe2O4) nanoparticles were carried by XRD, FE-SEM, TEM, EDS, FTIR, VSM, and Low-temperature magnetization FC-ZFC techniques. The observed results reveal that both samples belong to cubic spinel structure with Fd-3m space group, spherical in nature and exhibit superparamagnetism with saturation magnetization (Ms) values of ~81 emu/g. Amorphous layers of coating with hydrodynamic diameters of ~95-192 nm were observed in the results that affect magnetic properties and blocking temperature of the OA-NiFe2O4 nanoparticles. The OA-NiFe2O4 nanoparticles were used to prepare magnetic nanofluid. The stability of the magnetic nanofluids was analyzed by UV-Vis, Zeta potential measurement methods and found to be stable more than 11 days. These nanofluids were analyzed for magnetic fluid hyperthermia applications. Magnetic fluid hyperthermia studies reveal that the OA-NiFe2O4 nanoparticles were significantly contributed to generating heat for killing cancer cells. Further study also reveals the low concentration of the OA-NiFe2O4 nanoparticles will be promising candidates for magnetic fluid hyperthermia therapeutics applications. References: 1. Kharat P.B., Humbe A.V., Kounsalye J.S. and Jadhav K.M., (2019). Thermophysical investigations of ultrasonically assisted magnetic nanofluids for heat transfer. Journal of Superconductivity and Novel Magnetism, 32(5), pp.1307-1317. 2. Kharat P.B., More, S.D., Somvanshi S.B., & Jadhav K. M. (2019). Exploration of thermoacoustics behavior of water-based nickel ferrite nanofluids by ultrasonic velocity method. Journal of Materials Science: Materials in Electronics, 30(7), 6564-6574.

Mr Ashwini Kumar BeheraImage Delegate ID Theme Details


Research



A simple method for the localization of a separable nonlocal interaction is formulated in terms ofthe regular and irregular solutions for motion in a particular potential field. Our approach to theproblem is based on simple rearrangement of the Schrödinger equation. The problem withelectromagnetic plus separable nonlocal interactions is considered here which encountered in chargedhadron scattering. The constructed energy momentum dependent equivalent local potential with regularboundary condition is real while that for the irregular boundary condition is complex in nature. Thephase function method (PFM) is exploited, as it permits a rigorous inclusion of the electromagneticeffect for scattering of charged hadron systems, to compute elastic scattering phase shifts for thealpha-nucleon systems. Reasonable agreements in scattering phase shifts with experimental data areobtained, particularly, in the low energy range for the systems under consideration. The phaseshifts for the imaginary parts of the potentials derived from the irregular solutions for thealpha-nucleon systems, however, give indications of resonances at very low energies.

Mr Anbazhakan KImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Bannari

Amman Institute of Technology

Designation : Research Scholar (Ph.D)

Abstract: The performance of the Na- ion batteries at well- defined conditions is directly affected by different factors such as temperature voltage and capacity. However, to meet the space application batteries with high density have the most priority because of the high power output and the low weight requirements. After the long survey V2O5 nano materials are superior due to its high theoretical capacity and controlled phase changes (?,?,?,?,?) which can effectively decrease the quick capacity fading than the other metal oxides. The other factors such as optimum temperature dependent on the specific battery chemistry, the chemical reaction between V2O5 and TM makes the battery to perform good at lower temperatures. By adding surfactant the chemical deterioration can effectively reduce at higher temperature, to beat the voltage window and current density, the nano composites V2O5 + TM + Less % of surfactant could serve the better electrochemical performance for the Na ion batteries. More over higher valance states in the nano composites of V2 O5 would lead a pathway for Na ions hence V2O5 based cathode materials would effectively reproduce the current density after long cycle. The aim of this review is to provide an in-depth and rational understanding of how the electrochemical properties of V2O5-based cathodes can be effectively enhanced by achieving proper nanostructures with optimized chemical composition.

Keywords :TM- Transition metal Na ion batteries- sodium ion batteries

Mr SUMIT KUMAR SHRIVASTAVAImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Indira Gandhi

PlanetariumDesignation : Scientific

Officer

ABSTRACT The origin and development of the technology of preparation and application of gold powder (Traditional Name) or powder containing Gold Nano particles have a long history in ancient India. In many Sanskrit texts there are literary evidences of the use of “Bhasma”, which is nothing but the powdered form of precious metals, in ancient Indian civilization. Making of Gold Nano Powder is very costly in present times and it was the same in ancient India. Ancient Indians had a deep understanding of the morphology and size of naturally occurring gold powder as well as optical properties of gold nano particles. They were aware of the theruptic uses of gold nano particles and it was widely used for medical purpose by the name of “Swarna Bhasma”. Now a days large number of techniques namely, Gas Condensation, Vacuum Deposition and Vaporization (CVC & CVD), Mechanical Comminution, Chemical Precipitation, Sol-Gel Techniques, Electrodeposition etc. are available to synthesize different types of Nano-materials in the form of colloids, clusters, powders, tubes, rods, wires and thin films etc. These techniques are mainly classified in four methods: (a) Physical methods (b) Chemical methods (c) Biological methods (d) Hybrid methods As far as the synthesis of Gold Nano Particles in ancient Indian society is concerned, we find there were mainly two techniques being used are — mechanical grinding and chemical methods. Also evidence of many variants of these techniques in ancient India were also found. This report is an effort to compare and discuss the various procedures of preparation of Gold Nano particle and their applications in todays time and preparation and application of the gold powder in ancient India. KEYWORD : Swarna Bhasma, Literary Evidences, Optical Properties, Medical Uses, Natural Gold

Sumit Kumar Shrivastava, Shikha Srivastava, Dr. Rajesh Gangwaar AMITY UNIVERSITY, LUCKNOW e-mail : [email protected], phone no. 8009855777

Mr PRATIK PATILImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : T C College

Baramati Designation : Project fellow

Nickel sulphide is one of the proficientelectrode materialsintended at high performance supercapacitors. Current abstract portrays about synergetic impact of Complexing agent and heat treatment in improving structural, optical andelectrochemical performance of nickel sulphide thin filmelectrode synthesized by chemical bath method. Deposited Nickel Sulphide thin films were characterized as consequence of heat treatment forinvestigation of optical, structural and electrochemical properties.The X-ray diffraction studies revealed role of complexing agent in controlling crystallite size (30 nm to 14 nm); however post heating effect refurbished in escalation of crystalline size (50 nm to 21 nm)showingpolycrystalline nature. Average dislocation densitywasvaried in the range of 0.0012 to 0.0051 m-2 andthemicro strain was found to be in the range of 0.0012 to 0.0023 for Nickel sulphide films. Furthermore, optical band gap observed to be decreased after annealing from 2.50 to2.05 eV.This procedural effect resulted in boosting of specific capacitance of nickel sulphide electrode to652 Fg?1 at of 20 mV/sscan rate and 578 Fg-1at a current density of 1mAg-1in 1M KOH electrolyte.Thus synergetic impact of controlling growth kinetics by Complexing agent and post heating resulted into improved electrochemical performance. Keywords:Complexation & Heat treatment, Nickel sulphide, CBD, Structural, Electrochemical properties

Mr Joshi Yogeshkumar DileepkumarImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Poornima University, Jaipur / IASCDesignation : Bachelor

Student

The International Astronomical Search Collaboration (IASC) is an educational outreach program forhigh school and college students. It provides high quality astronomical data to students around theworld in order to analyze and search for potential moving objects and Near Earth Observations.Students prepare a report and send it to the IASC which is further studied by IAU- Minor PlanetCenter. Image sets provided are taken using 1.8 m Pan-STARRS (Panoramic Survey Telescope and RapidResponse System) at Haleakala Observatory, Hawaii, USA. Participating students are provided thesedata online and they are able to make original astronomical discoveries and participate in hands-onastronomy. This service is provided at no cost to the participating college students. We presentthe procedure and analysis to search for Moving Objects with Astrometrica Software from dataprovided by IASC.

Ms SINDHUSHA SImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Nesamony memorial Christian College,

MarthandamDesignation : Assistant

Professor

Abstract Nonlinear optical (NLO) single crystals of creatinine with cinnamic acid were grown by slow evaporation technique at room temperature using de-ionized water as solvent. The grown crystals were characterized by Single crystal X-ray diffraction pattern to confirm the lattice parameters. Hirshfield surface analysis of grown single crystal was performed to visualize the presence of intermolecular interactions. UV-Visible absorbance spectrum was recorded to study the optical transparency and optical parameters such as band gap energy, refractive index, extinction coefficient etc. The band gap energy of the molecule can be theoretically examined from the Frontier molecular orbital analysis. The MEP plot of CRCN predicts the reactive sites of electrophillic and nucleophillic attack for the crystal. The nonlinear optical parameters such as dipole moment, polarizability, first order hyperpolarizability and second order hyperpolarizability were theoretically calculated. The third order optical nonlinearity has been confirmed by Z-scan analysis. The mechanical strength of the synthesized single crystal has been examined by Vicker’s micro hardness test. Thermal stability of the material has been studied by TG/DTA analysis.

Mr DAVID WILLINGTON TImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Nesamony memorial Christian College,

MarthandamDesignation : RESEARCH

SCHOLAR

Abstract The aim of this work is to investigate the synthesis, growth and physiochemical properties of 2-Methylpyridinium picrate (2MPP) single crystal. Optically transparent and defect free crystal was grown from aqueous solution by slow evaporation technique at room temperature. Single crystal X-ray diffraction (SXRD) study reveals that the crystal is triclinic system with space group P1 and the calculated lattice parameters are a=8.1524Å, b=11.8809Å, c=14.6377Å and V=1361.21Å3. The experimental crystallographic parameters have been compared with the calculated theoretical values. The intermolecular interactions were illustrated by using Hirshfield suface analysis. The optical absorption of 2MPP single crystal was recorded using UV-Visible absorbance spectral analysis and linear constants such as the absorption coefficient, band gap, extinction coefficient, refractive index and reflectance were calculated. HOMO & LUMO energy gap has been calculated and analysed. Mechanical strength of the grown crystal was found out by using Vickers microhardness test. Second Harmonic Generation was confirmed by using Kurtz and Perry powder technique.

Mr Sandeep SomvanshiImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Dr.

Babasaheb Ambedkar Marathwada University


Though there is tremendous advancement in the field of medicine in recent years, many diseases likecancer still remains as a leading cause of death in the world. Improper diagnosis and detection atearly stages are the some of the reasons behind it. Also, the treatment now followed for treatingcancer like diseases including radiation therapy, immunotherapy, chemotherapy are comprised of sideeffects such as hair loss, eye irritation etc. Thus to diagnose the cancer and all other diseases atthe early stage and to cure it without much side effects remains a challenge to scientificcommunity. The new tool, magnetic nanoparticles are playing vital role in diagnosis and therapy ofvarious diseases. The magnetic hyperthermia therapy in which the magnetic nanoparticles used to heatspecific organ or whole body (depending upon the tumor) has emerged as one the promising cancermodality either alone or in combination with other existing cancer modalities. In light of this, thepresent work focuses on development and characterizations of highly functionalized,superparamagnetic and biocompatible spinel structured magnetic nanoparticles and their nanofluidsfor biomedical applications in particular magnetic fluid hyperthermia to achieve the selectivewarming of the given areas of a cancer cells by TC-limiting production of controlled heat effects bymeans of an alternating external magnetic field.

Mr Jahiruddin SkImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : SNGGDCG,

Alipore, Kolkata - 700027Designation : Assistant

Professor

The natural DNA has four bases, namely Adenine, Thymine, Guanine and Cytosine. Experimentalists aredesigning new unnatural base pairs which are well fitted in DNA and taking part in replication andtranscription. Recently, Romesberg and coworkers have reported the synthetic design of E. colibacteria that contains hydrophobic UBPs and d5SICS-dNaM (Figure 1a) within its DNA and is able tosustain and replicate under intracellular conditions. Followed by d5SICS-dNaM, several other UBPs,such as dTPT3–dNaM, dTPT3–dFIMO, dTPT3–IMO, dTPT3–FEMO, FTPT3–NaM, FTPT3–FIMO,FTPT3–IMO, and FTPT3–FEMO, have demonstrated similar or better retention and fidelity insidecells. Our Quantum chemical calculations show that the UBPs prefer a slipped parallel configurationto facilitate weak dispersion interactions somewhat similar to the so-called ?-stacking interaction.When arranged between two natural base pairs, the UBPs exhibited binding energy similar to that ofthree-base sequences of natural bases. Our computational data show that the most promising basepairs are 5SICS–NaM, TPT3–NaM, and TPT3–FEMO. Within a natural DNA tract, classical moleculardynamics simulations show that the backbone and neighbouring stacked bases together reorient theUBPs in natural base pair like planar environment. Our computed structure with an average end-enddistance, dC1??C1? = 10.7 Å for d5SICS-dNaM is in excellent agreement with available crystalstructure (PDB ID: 3SV3, planar UBP with dC1??C1?crystal = 11.0 Å). Quantum mechanical calculationsfor the UBP flanked by two natural base-pairs (A?T) on top and on bottom on equilibrated MDstructure found large binding energy (?E = ?74.0 kcal/mol). The present calculations thereforeestablish the fact that the hydrophobic UBPs can be stabilized by dispersion interactions with otherbase pairs in the DNA tract even in the absence of any hydrogen bonding between the UBPs themselves.

Mr ASHITH V KImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : St Phiolmena

CollegeDesignation : Assistant

Professor

In current years, the understanding of II-VI semiconductor nanofilms required significant attention because these films offer an essential role in optoelectronic device technology. Among the II-VI semiconductors nanofilms, cadmium telluride (CdTe) thin film is one of the most promising materials for photovoltaic devices from the standpoint of both cost and efficiency. In the present work, CdTe nanofilms were deposited by vacuum evaporation technique with the variation of thickness. The films were found to be polycrystalline with a cubic phase. The crystallite size of the films varied with respect to the thickness. The bandgap of the films was found to be 1.5eV from the absorbance spectra of the films and it changed only marginally with thickness. The defect was confirmed by the analysis of photoluminescence. The electrical properties of the films were confirmed that deposited CdTe thin film (thickness 900nm) suitable for optoelectronic devices.

Mr SIDDHARTH PRATAP SINGHImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Dr. RL Avadh

UniversityDesignation : Phd Scholar

There has been an important contribution of BEOS (Brain Electrical Oscillation Signature Profiling)system and management. It had always helped in providing evidence which would further help to reacha correct decision. BEOS had been able to perform this because of its realistic and experimentalprocedures and operations. BEOS may be considered as application of Science and Technology foranswering the question of legal interest. Scientists apply various tools and techniques to explorethe information which may be helpful in investigations or interpreting the crime scene. Thesetechnicians and scientist are basically a pool of Law Enforcement, Life Science, Physics andChemistry. However there are several changes occurring today which are causing various communicationproblem between Criminal Justice System Management and BEOS technique. In this review paper we willdiscuss about both the sides of the coin of BEOS when applied in Criminal Judicial System andManagement.

Ms Dhivya AngelinImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Bishop Heber

college Designation : Assistant

professor

Low energy density is one of the most intensive approaches is the development of nanomaterials for supercapacitor electrode. Nanostructures of metal oxides helps to stabilize appreciably higher electrochemical characteristics used to overcome the obstacle. The transition metal oxides of TMO doped ZnO has been synthesised by Co-precipitation method on Ni foam as substrate. The as-prepared materials were analysed by powder XRD, FTIR, FESEM and EDX. Pseudocapacitive activities including specific capacitance values are calculated using cyclic voltammetry(CV), charge – discharge (CD) and impedance spectroscopy (EIS) characterisation techniques used to analyse the properties. It can be considered as one among the promising material for next generation of supercapcitors owing to the unique physical and chemical properties. Keywords : Supercapacitor, TMO’s, Nanostructures, Pseudocapacitors

Ms Manasi MahadikImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : RUSA Centre

for Advanced Sensor Technology, Dept. Physics, Dr. Babasaheb Ambedkar

Marathwada UniversDesignation : Research

Scholar

Title-Detection of aqueous pollutant heavy metal ions in water Authors Name-Manasi M Mahadik, Mahendra D Shirsat Affiliation-RUSA-Centre For Advanced Sensor Technology, Dept. of Physics, Dr. Babasaheb Ambedkar Marathwada University,Aurangaba, Maharashtra, India-431004 Contact Author’s e-mail address: [email protected]

Abstract: Heavy metals are moderately scarce in the Earth's crust. These heavy metals are well defined metals with relatively high densities, atomic weights, or atomic numbers [1]. Heavy metals like cadmium, mercury, and lead, are highly toxic and carcinogenic above trace level [5,6]. Hg (II) ions detection was done by electrochemical method using EDTA modified polyaniline (PANI)/Graphene Oxide (GO) composite. Graphene Oxide (GO) synthesis was carried out by modified Hummer’s method. Electrochemical characterizations such as cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were done before and after modification of composite. Topography of PANI/GO composite and EDTA_PANI/GO electrodes were studied using AFM. Roughness parameter were compared for confirmation of surface modification. Fourier transform infrared spectroscopy (FTIR) was used for the compositional analysis of PANI/GO and EDTA_PANI/GO electrodes. The EDTA_PANI/GO composite shows sensitivity towards Hg (II) ions and detected using Differential pulse stripping voltammetry (DPSV) technique at the lower detection limit of 2 ppb.

References: ? N. Tekaya, O. Saiapina, H. Ben Ouada, F. Lagarde, H. Ben Ouada, N.Jaffrezic-Renault, (2013). “Ultra-sensitive conductometric detection of heavy metalsbased on inhibition of alkaline phosphatase activity from Arthrospiraplatensis”,Bioelectrochemistry 90 24–29, doi:10.1016/j.bioelechem.2012.10.001. ? C. Gao, X.Y. Yu, S.Q. Xiong, J.-H. Liu, X.J. Huang, Electrochemical detectionof arsenic(III) completely free from noble metal: Fe3O4microspheres-roomtemperature ionic liquid composite showing better performance than gold,Anal. Chem. 85 (2013) 2673–2680, http://dx.doi.org/10.1021/ac303143x ? L. Maria, Biosensors for Environmental Applications, 2011, pp. 1–16, http://www.intechopen.com/books/environmental-biosensors/biosensorfor-environmental-applications

Mr Raju DasImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Innovation Hub (North Bengal Science

Centre)Designation : Student

Member

Adulteration of chemicals or any other cheaper oil or chemical with pure food oil is common malpractice which is highly dangerous and is threatening to our human body. Due to changing social values where companies are focusing on reaping rich profits, adulteration is prevalent in almost all commodities such as food items, fuel, cloths and construction materials. Basically, Argemone oil, poor quality of soya oil and various chemicals are is mixed with mustered oil to increase its quantity and enhance its color. Hence this project presents a simple, extrinsic intensity modulated fiber optic sensor for determining adulteration in mustered oil. This sensor is based on a polished plastic optical fibre. At the sensing region, the cladding and a small portion of the core are removed and the fibre nicely polished. The sensing region is fabricated in such a manner that it sits like U bend shape inside a box. This bending of the sensing region enhances its sensitivity. Here Soya oil has been taken as adulterant and the oil mixture of different mix ratios is introduced into the sensing region. By measuring the output intensity by a LDR receiver sensor of laser light through the optical fibre a calibration has been made by Arduino microcontroller board to determine the unknown density and amount of adulteration present in pure mustered oil. An alarm and LCD display have been introduced for getting the information about quality of specific food oil. The main advantage of this device is it require a very small quantity of sample. A 9v rechargeable battery is fixed to power all the measuring components. The main working principle of this proposed device is change in refractive index and the effect of evanescent field.

Mr Suman ChandImage Delegate ID Theme Details


Research


Institute of Technology Ropar (IIT Ropar)

Designation : PhD research scholar

Abstract: The current laws of thermodynamics apply only to large objects when many particles are involved. The thermodynamics laws for smaller systems are not well understood, but they will have implications for quantum computer development. The quantum heat engine (QHE) is one way to deal with this. Since the real engine must be implemented in physical frameworks, such as spin chains, it is a natural question of how the QHE acts near or across the quantum phase transition point (QPT). In this study, we examine the signatures of a QPT in the work and efficiency of a QHE, which is implemented by using a two-ion system as a working substance subjected to a magnetic field. At the quantum critical point, the long-range interaction between the interacting particles becomes dominant, corresponding to a QPT. We show that such a long-range interaction can significantly improve the heat engine’s efficiency. The ion-ion interaction leads to greater efficiency at the critical point than a single-ion heat engine. However, coupling to an auxiliary ion deteriorates the engine’s performance. This model is feasible with today’s trapped ion technology. This can also be regarded as a prototype for studying the system’s behavior at a quantum critical point, even without reaching absolute zero temperature.

References: 1. S. Chand and A. Biswas, Phys. Rev. E. 2018, 98, 052147-1 – 052147-8

Dr Judith JayaraniImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Bishop Heber

College Designation : Assistant

Professor

Low energy density is one of the most intensive approaches is the development of nanomaterials for supercapacitor electrode. Nanostructures of metal oxides helps to stabilize appreciably higher electrochemical characteristics used to overcome the obstacle. The transition metal oxides of TMO doped ZnO has been synthesised by Co-precipitation method on Ni foam as substrate. The as-prepared materials were analysed by powder XRD, FTIR, FESEM and EDX. Pseudocapacitive activities including specific capacitance values are calculated using cyclic voltammetry(CV), charge discharge (CD) and impedance spectroscopy (EIS) characterisation techniques used to analyse the properties. It can be considered as one among the promising material for next generation of supercapcitors owing to the unique physical and chemical properties.

Keywords : Supercapacitor, TMOs, Nanostructures, Pseudocapacitors

References: W. Hu, R. Chen, W. Xie, L. Zou, N. Qin and D. Bao, ACS applied materials & interfaces, 2014, 6, 19318-19326. 2. H. Chen, S. Zhou and L. Wu, ACS applied materials & interfaces, 2014, 6, 8621-8630. 3. M. Yassine and D. Fabris, Energies, 2017, 10, 1340.

Mr Praveen Prakash Dsouza PImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : St Philomena


Professor

The exact analytical solution of the Schrödinger equation for its bound state energy levels andeigenfunction is fundamental in understanding the bound energy spectrum in non relativistic andrelativistic quantum mechanics. The wave function contains all necessary information for thecomplete description of a quantum mechanical system. The Schrödinger wave equation is one of thefundamental wave equation. Its solution plays an essential part in particle Physics. There arevarious methods available in literature for its solution. The Green's function technique takes adifferent approach, by excluding a part of the potential term from the solution initially which canbe included later after finding the Green's function. For the radial wave equation the Green'sfunction is worked out. Using an improved approximation of the centrifugal term. The bound stateenergy eigenvalues and the normalized eigenfunctions are given in terms of hyper geometricpolynomials. The wave functions are generated and plotted for different values of the parameters.Hulthen potential and their eigenfunctions are obtained having same eigenvalue spectrum. Thedeformed potential and the eigenfunctions approaches to their unreformed case for large values ofthe parameter.

Dr TILAK NARAYAN GHOSHImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Midnapore

College (Autonomous)Designation : Assistant

Professor

Abstract Graphene oxide (GO) has many potential applications due to its unique mechanical, thermal, and chemical properties [1, 2, 3]. Graphene oxide was first prepared from graphite by a modified Hummers and Offeman method [4]. Then the requisite amount of hydrazine was added to the mixture and it was stirred constantly overnight. The colour of the mixture turn black but no precipitate was formed. It meant that the GO nanofillers were converted into the RGO nanofillers. Then Graphene Oxide- poly-acrylic acid (PAA-GO) and Reduced Graphene Oxide- poly-acrylic acid (PAA-RGO) nanocomposites film with GO and RGO as 5 wt% respectively were prepared by solution mixing method in water [5, 6]. The optical parameters viz reflectivity at normal incidence RV(f) and Electron Energy Loss Parameter (EELP) were calculated [7, 8] from the dielectric measurements of the samples using HIOKI IM 3536 LCR-meter in the frequency range from 20 Hz to 1 MHz. The reflectivity at normal incidence RV(f) was calculated by the relation RV(f)=((n-1)^2+k^2)/((n+1)^2+k^2 ) where n(f) and k(f) are the real part and the imaginary part of the refractive index. The energy of the electrons are lost in a dielectric medium mainly due to various inelastic interactions such as phonon excitations, inter and intra band transitions of electrons, plasmon excitations, and inner shell ionizations. The energy loss due to collective excitation of the phonon inside the system was determined by calculating the parameter EELP with the following relation EELP=?_2/(?_1^2+?_2^2 ) where ?_1 and ?_2 are the real and imaginary parts of dielectric constant ?.

Mr Bidhan KhiraliImage Delegate ID Theme Details


Research



Ordinary differential approach together with certain properties of Gaussian hypergeometric functionsis exploited to construct exact analytical expressions for regular and irregular solutions in allpartial waves for motion in Manning-Rosen potential. The Jost function thus obtained from the nearthe origin behaviour of the irregular solution is used appropriately to compute scattering phaseshifts for the neutron-proton and neutron-deuteron systems for few lower partial waves. Our resultsare in good agreement with experimental data.

Mr HARI Shankar YADAVImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Atma Ram

Sanatan Dharma College, DUDesignation : Student(

Young Researcher)

Effect of various salts concentration on Biopolymer electrolytes for electrochemical device applications HariShankarYadav1, Dr.YogeshKumar2, Dr. Raghvendra2, A.K.Singh2, Dr.Javid Ali3 and Mohd.Sadiq2 1. Department of Chemistry A.R.S.D.College University of Delhi-110021 2. Department of Physics A.R.S.D.College University of Delhi-110021 3. Departments of Physics, Jamia Millia Islamia University, India Email ID: [email protected], [email protected] Abstract: The new solid biopolymer electrolyte(BEs) is creating good opportunity for new types of research in energy storage/conversion devices applications such as high energy density batteries(Li,Na, and Mg), supercapacitor, sensor, and may be good for many industrial areas. Biopolymer cellulose acetate(CA) doped with different salts(Na,Mg), were prepared by standard solution-casting method. Keeping in view the following characterization results obtained in the present paper. This result had been further proved by X-ray diffraction(XRD), Fourier transform infrared(FTIR) spectroscopic techniques, electrical impedance spectroscopy study. Reference 1. Ramlli, M. A., & Isa, M. I. N. (2015). Solid Biopolymer Electrolytes Based Carboxymethyl Cellulose Doped With Ammonium Fluoride: Ionic Transport and Conduction Mechanism. Polymers from Renewable Resources, 6(2), 55-63. 2. Samsudin, A. S., & Isa, M. I. N. (2012). Characterization of carboxy methylcellulose doped with DTAB as new types of biopolymer electrolytes. Bulletin of Materials Science, 35(7), 1123-1131. 3. Monisha, S., Selvasekarapandian, S., Mathavan, T., Benial, A. M. F., Manoharan, S., & Karthikeyan, S. (2016). Preparation and characterization of biopolymer electrolyte based on cellulose acetate for potential applications in energy storage devices. Journal of Materials Science: Materials in Electronics, 27(9), 9314-9324. 4. Abidin, S. Z. Z., Ali, A. M. M., Hassan, O. H., & Yahya, M. Z. A. (2013). Electrochemical studies on cellulose acetate-LiBOB polymer gel electrolytes. Int J Electrochem Sci, 8, 7320-7326. 5. Bresser, D., Lyonnard, S., Iojoiu, C., Picard, L., & Passerini, S. (2019). Decoupling segmental relaxation and ionic conductivity for lithium-ion polymer electrolytes. Molecular Systems Design & Engineering.

Dr Debabrata DasImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Jadavpur


Associate

Cellulose nanocrystals (CNCs) have been received much attention as renewable, biodegradable, nontoxic, low-cost nano-materials having large surface-to-volume ratio, high tensile strength, high stiffness and high flexibility to be used as an environment-friendly cost-effective reinforcing agent [1]. Rice husk (RH) is widely available agro-waste (~25 million tons/year) in India [2]. The major amount of RH is produced in rice milling industry, where it is reused as fuel and the large amount of ash is dumped causing environmental problems such as air pollution, soil erosion, and a decrease in soil biological activity. RH could be utilized as a major source of cellulose [3]. Present study is aimed to evaluate the potential of RH as a source of CNCs. CNCs are isolated from RH samples by chemical route. Alkali extraction followed by bleaching treatment is performed to remove hemicellulose and lignin. Bleached white fibers are subjected to acid hydrolysis and high intensity ultrasonication to isolate CNCs. Field emission scanning electron microscopy studies reveal that during the extraction process the dimension of RH fibers deceased gradually to finally obtained the nanocellulose (~50±10 nm). X-ray diffraction studies show the characteristic peaks related to CNCs structure and highest crystallinity index is observed for CNCs (~80). Fourier-transform infrared spectroscopy studies of the four stages of extraction show the removal of groups related to hemicellulose (1737 cm-1), lignin (1462 cm-1) and that related to cellulose (1160 cm-1) become prominent. The thermal stability of raw RH and CNCs are observed by thermogravimetric analysis (TGA) and derivative thermogravimetric analysis (DTG). First degradation region accounted for hemicellulose decomposition ~170°C for raw RH is absent on CNCs due to the removal of it. CNCs show thermal stability up to ~340°C. These promising results prove revalue of ricehusk agro-waste for the production of CNCs and its potential use as reinforcement in nanocomposites.

Mr Mintu DebnathImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : University of

KalyaniDesignation : Research

Scholar

We report the magnetoresistance along with the temperature and field coefficient of resistance ofPr0.5Ca0.5Mn0.95V0.05O3 (PCMVO) compound. After mixing the required oxides in stoichiometric ratio,the sample has been prepared using solid-state reaction. Rietveld refinement of XRD data reveals thesingle-phase orthorhombic structure of the sample with Pmna space group. The sample provides theMn3+/Mn4+ ratio greater than unity due to incorporation of non-magnetic (3d0) V5+ ions which leadsto a ferromagnetic metallic state. The obtained the maximum value of magnetoresistance (MR) for 7Tapplied magnetic field is 88.5% at 37K while the maximum TCR and FCR percentage values in thiscompound are found to be 208 K-1 and 33.8 T-1 respectively. These higher values of the sample standit as a potential applicant for memory devices and bolometric applications.

Ms SANGEETHA PRASADImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : SN COLLEGE

FOR WOMEN KOLLAMDesignation : STUDENT

Green Synthesis of Silver Nanoparticles and Study of its catalytic and bactericidal activity Sangeetha Prasad* and S. Saravana Kumara Department of Physics, SN College for Womens, Kollam, Kerala aDepartment of Physics, NSS College Pandalam, Pathanamthitta, Kerala [email protected] Abstract: In this work, nanoparticles of silver were synthesized using Zingiber officinale (ginger) extract as reducing agent. X-ray diffraction pattern of the nanoparticles of silver synthesized using silver as reducing agent were recorded and from the XRD pattern, it was observed that the samples are in cubic phase. The grain size of the samples calculated from XRD pattern using Debye-Scherrer equation was approximately 68 nm. The UV-Visible absorption spectra of nanoparticles of silver synthesized using Zingiber officinale (ginger) extract were recorded. Silver nanoparticles provided an alternative path for the reaction since they require a lower energy of activation. The antibacterial activity of silver nanoparticles synthesized using ginger extract as reducing agent was studied on Alcaligenes faecalis.

Reference:

1.Kundu S, Ghosh SK, Mandal M, Pal T. Bulletin Mater Sci 25, 577(2002)

Ms Shilpa PrasadImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : NSS College

PandalamDesignation : Research

Scholar

Synthesis, Characterization and Study of Photocatalytic Activity of TiO2 Nanoparticles Shilpa Prasad*, Saravana Kumar Sa *Department of Physics, NSS College Pandalam, Pathanamthitta, Kerala aDepartment of Physics, NSS College Pandalam, Kerala, India [email protected]

Abstract: Titanium dioxide (TiO2) is the naturally occurring oxide of titanium. It is a versatile transition-metal oxide and a useful material in various present and future applications related to catalysis, electronics, photonics, sensing, medicine, controlled drug release, pigmentations, cosmetics, coatings, and water purification. Nanoparticles of TiO2 have attracted significant interest of materials scientists and physicists due to their special properties and have attained a great importance in several technological applications such as photocatalysis, sensors, solar cells and memory devices. Titania commonly exists in anatase (tetragonal), brookite (orthorhombic), rutile (tetragonal). In the present work, TiO2 nanoparticles prepared by a simple chemical precipitation method using titanium tetra isopropoxide as a precursor. X-ray diffraction pattern of the TiO2 nanoparticles were recorded and compared with the standard JCPDS values. From the comparison, it was found that more prominently in Rutile phase. The grain size of TiO2 nanoparticles was calculated from Debye-Scherrer equation and was found to be approximately 49 nm. The band gap of the nanoparticles of TiO2 was calculated from the UV-Visible absorption spectrum and was found to be 3.3 eV which was larger than for bulk nanoparticles. The photo catalytic activity of TiO2 nanoparticles were studied on photo degradation of methylene blue. Reference: 1. Hoffmann M R, Martin S T, Choi W, et al. Environmental applications of semiconductor photocatalysis. Chem Rev, 1995, 95: 69–96. 2. Linsebigler A L, Lu G, Yates J T. Photocatalysis on TiO2 surfaces: Principles, mechanisms, and selected results. Chem Rev, 1995, 95: 735–758.

Mr SIDDHARTH PRATAP SINGHImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Dr. RL Avadh

UniversityDesignation : Phd Scholar

Pros and Cons in Application of BEOS Profiling in Legal System And Management Siddharth Pratap Singh1 , Akshita Gupta2 , Rajat Sharma3* 1 PhD Scholar, Department of Physics and Electronics, Dr Rammanohar Lohia Avadh University, Ayodhya- 224001, Uttar Pradesh, India 2 PhD Scholar, Institute of Management, Commerce and Economics, Shri Ramswaroop Memorial University, Lucknow – Deva Road 225003, Uttar Pradesh, India 3 PhD Scholar, Department of Computer Application, Shri Ramswaroop Memorial University, Lucknow – Deva Road 225003, Uttar Pradesh, India [email protected]

Abstract: There has been an important contribution of BEOS (Brain Electrical Oscillation Signature Profiling) system and management. It had always helped in providing evidence which would further help to reach a correct decision. BEOS had been able to perform this because of its realistic and experimental procedures and operations. BEOS may be considered as application of Science and Technology for answering the question of legal interest. Scientists apply various tools and techniques to explore the information which may be helpful in investigations or interpreting the crime scene. These technicians and scientist are basically a pool of Law Enforcement, Life Science, Physics and Chemistry. However there are several changes occurring today which are causing various communication problem between Criminal Justice System Management and BEOS technique. In this review paper we will discuss about both the sides of the coin of BEOS when applied in Criminal Judicial System and Management.

Keywords: Forensic Science, Criminal Judicial System and Management, BEOS Profiling

Mr Amrit kumar MishraImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Lucknow


scholar

Degradation in the flexible organic-inorganic hybrid perovskite solar cells

Amrit Kumar Mishra* and R.K.Shukla ** Department of physics, University of Lucknow -226007 Corresponding author: [email protected] [email protected]

Abstract

Energy harvesting is a best technique to solve energy problem of the world. We are using perovskite materials for energy harvesting has great photovoltaic properties as a solar cell device. The energy band gap of solar is 1.51eV which is suitable for the maximum power conversion efficiencies and it is applicable for broad range of wavelength. Although perovskite solar cells with power conversion efficiencies (PCEs) more than 22% have been realized with expensive organic charge-transporting materials, their stability and high cost remain to be addressed. The device structure of solar cell: FTO/Compact TiO2/Mesoporous TiO2/CH3NH3PbI3/SPIRO-MeOTAD/Gold. Here TiO2 and SPIRO-MeOTAD working as an ETL (Electron transporting materials) and HTM (hole transporting materials) respectively. Degradation due to humidity is a big task of perovskite materials industrialization, band gap tuning and immunization of perovskite materials by SPIRO-MeOTAD layer to improve stability of perovskite solar cell.

Keywords: Photostatic, energy band gap, stability, degradation, efficiency.

References: 1 Yang WS, Noh JH, Jeon NJ, et al. High-performance photovoltaic perovskite layers fabricated through intramolecular exchange. Science, 2015, 348: 1234–1237

2 Saliba M, Matsui T, Seo JY, et al. Cesium-containing triple cation perovskite solar cells: improved stability, reproducibility and high efficiency. Energy Environ Sci, 2016, 9: 1989–1997

3 Hades G. Perovskite-based solar cells. Science, 2013, 342: 317–318

4 Kojima A, Teshima K, Shirai Y, et al. Organometal halide perovskites as visible-light sensitizers for photovoltaic cells. J Am Chem Soc, 2009, 131: 6050–6051

5 Xing G, Mathews N, Sun S, et al. Long-range balanced electron and hole-transport lengths in organic-inorganicCH3NH3PbI3. Science, 2013, 342: 344–347

Ms CHETANA GHOSALImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : JADAVPUR

UNIVERSITYDesignation : PHD

SCHOLAR

Nucleation of Electro-active Phase in Bacterial Protein doped Poly (vinylidene fluoride) for Energy Harvesting Applications

Chetana Ghosal1,a), Sujoy Kumar Ghosh2,b), Dipankar Mandal2,3,c) , Brajadulal Chattopadhyay1,d)

1Department of Physics, Jadavpur University, Kolkata 700032, India 2Organic Nano-Piezoelectric Device Laboratory (ONPDL), Department of Physics, Jadavpur University. Kolkata 700032, India 3 Institute of Nano Science and Technology, Phase-10, Sector-64, Mohali, 160062, India. a) [email protected] b) [email protected], [email protected] c) Corresponding author: [email protected], [email protected] d) Corresponding author: [email protected]

Abstract: Harvesting energy is one of the most promising techniques in response to the global energy problem without depleting natural resources. Energy harvesting is the conversion of ambient energy, exist in the environment into electrical energy [1]. In this context, piezo-electric polymer materials are attractive such as PVDF and its copolymers which can be considered as one of the most important semicrystalline polymers, exhibiting electroactive response, including piezo-, pyro- and ferro-electric effects [2]. In this work, a composite film is prepared by incorporated thermophilic bacterial protein [3] with poly (vinylidene fluoride) (PVDF) which is free standing and flexible. Nucleation of electroactive ?-phase in poly (vinylidene fluoride) (PVDF) and consecutive surface morphological changes in presence of protein is systematically investigated. Finally, the PVDF/protein composite film is used to make a mechanical energy harvesting device. The flexible device produces open-circuit voltage under human touch. Here we use an eco-friendly biomaterial as an agent for the electro-active phase generation and for the preparation of the film which has a great importance for sustainable environment. Thus, the device can be used from self-powered bio-medical engineering to portable electronic gadgets in near future. References: 1. Kazmierski, T.J. and S.P. Beeby, Energy harvesting systems. Springer. 2010. 2. S. K. Ghosh, M. M. Alam, D. Mandal. RSC Adv. 2014, 4, 41886?41894. 3. Alam N, Sarkar M, Chowdhury T, Ghosh D, Chattopadhyay B. Adv Microbiol. 2016, 6:724-732

Prof Sarmistha BasuImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Behala

CollegeDesignation : Lecturer

Abstract: The gravitational waves originated from a pair of merging black holes. The gravitational wave background is a random gravitational wave signal produced by a large number of weak, independent, and unresolved sources. It is a possible target of gravitational wave detection experiments. The observational astronomy uses gravitational waves to collect observational data about sources of detectable gravitational waves such as binary star systems composed of white dwarfs, neutron stars, and black holes; and events such as supernovae, and the formation of the early universe shortly after the Big Bang. Observers detecting this radiation today are able to see the Universe at a very early stage on what is known as the `surface of last scattering'. Photons in the cosmic microwave background have been travelling towards us for over ten billion years, and have covered a distance of about a million billion billion miles. The cosmic microwave background radiation, corresponding to radiation from a blackbody at a temperature of nearly 3 K, is the greatly redshifted remnant of the hot universe as it existed about 380,000 years after the Big Bang. During the first 380,000 years of the universe, radiation and matter formed an opaque plasma called the primordial fireball. The detection of such a background would have a profound impact on early-universe cosmology and on high-energy physics.

Keywords: white dwarfs, neutron stars, supernovae, redshifted

Dr Samandeep SharmaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : GGDSD

College, ChandigarhDesignation : ASSISTANT

PROFESSOR

Abstract: It has been the long standing quest of mankind to look deep into the matter and understandit at the most fundamental level. As per our present level of understanding, all the matter aroundus is considered to be composed of 6 quarks (viz. up, down, charm, strange, top and bottom) and 6leptons (electron, muon, tauon and their corresponding neutrino flavors). These fundamentalparticles and their interactions are presently best understood in terms of "Standard Model ofParticle Physics". In the present talk, I would like to summarize numerous attempts on thetheoretical as well as experimental front to reach at this level, along with some salient featuresof the Standard Model. The achievements as well as shortcomings of the Standard Model, motivating usto look beyond it, would also be discussed. Some prominent beyond the Standard Model approaches suchas Grand Unified Theories, Supersymmetry etc. would also be discussed briefly. A brief introductionto some upcoming experiments designed to unravel various mysteries of particle physics would also bepresented.

Mr Nitin DwivediImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : university of

LucknowDesignation : Research

Scholar

Investigation of Adsorption Tyrphostin AG528 anticancer drug upon the Nitrogen doped carbon nanotube Nitin Dwivedi, R. K. Shukla* Department of Physics, University of Lucknow, Lucknow, Uttar Pradesh, India

*Corresponding author - [email protected].

Abstract In the present study, the interaction between new drug Tyrphostin AG5281-2 and Nitrogen doped CNT(3,3) nanotube by Density Functional Theory (DFT) calculations in an aqueous medium for first time have been investigated. According to calculations, the intermolecular hydrogen bonds take place between active positions of the molecule Tyrphostin AG528 and hydrogen atoms of the nanotube that plays an important role in the stability of the complex N-CNT (3, 3)/ Tyrphostin AG528. The non-bonded interaction effects of the molecule Tyrphostin AG528 with N- CNT (3, 3) nanotube on the electronic properties, chemical shift tensors and natural charge have been also detected. The natural bond orbital3 (NBO) analysis suggested that the molecule Tyrphostin AG528 as an electron donor and the N-CNT (3, 3) nanotube plays the role an electron acceptor at the complex N-CNT (3, 3)/ Tyrphostin AG528. The electronic spectra of the Tyrphostin AG528 drug and the complex N-CNT (3, 3)/ Tyrphostin AG528 were also calculated by Time Dependent Density Functional Theory (TD-DFT) for the investigation of adsorption effect of the Tyrphostin AG528 drug over nanotube. The use of N-CNT (3, 3) nanotube for Tyrphostin AG528 delivery to the diseased cells has been established. References: 1. Levitzki A, Mishani E. Tyrphostins and other tyrosine kinase inhibitors. Annu Rev Biochem 2006; 75: 93–109.

2. Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer 2009; 9: 28–39.

3. Sheikhi M, Shahab S, Filippovich L, Yahyaei H, Dikusar E, Khaleghian M. New derivatives of (E, E)-azomethines: Design, quantum chemical modeling, Experimental and theoretical investigations. J Mol Struct 2018; 1152: 368–385

Mr PRIYANATH MALImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : GURU GHASIDAS

VISHWAVIDYALAYADesignation : RESEARCH

SCHOLAAR

Topological insulators (TIs) are the novel class of materials with localized bulk states having timereversal symmetry protected topological surface states, showing linear Dirac dispersion, candirectly be imaged through angle resolved photoemission spectroscopy (ARPES) measurements.Experimental realization of TIs surface states via electronic transport studies is crucial for theirpractical applications and also to understand the basic physics, yet it is quit challenging to probethe surface sates in transport measurement as unlike ARPES this required physical contacts with thesample. ARPES measurements reveal PbBi2Te4 to be a 3D TI possessing single Dirac cone at ? point1.Theoretical calculations proposed SnBi2Te4, homologues to PbBi2Te4, also be a 3D TI2. Though Weakantilocalization for both the compounds is reported3,4, the non-trivial natures of the surfacestates are yet to set in transport measurements. Herein, we have reported the transport evidence ofnon-trivial topological surface states of SnBi2Te4 and PbBi2Te4 from the observed Shubinikov-de-Haas(SdH) oscillations with ? Berry phase. Determined lower effective mass from Lifshitz-Kosevich fitand higher mobility values obtained from dingle analysis confirms the surface origin of theoscillations. The observed weak anti-localization manifest the ? Berry phase acquires by the spinupon moving round the Dirac point and is consistent with SdH oscillations. For both the specimens anelongated band with non-trivial ? Berry phase outside the surface Fermi surface is identified.Comparative studies of different transport parameters ascertain PbBi2Te4 to be better topologicalinsulator over SnBi2Te4. Estimated Fermi level, lie well inside the bulk conduction band inPbBi2Te4. We are able to tune the Fermi level towards the Dirac point with successive magneticacceptor impurity doping in PbBi2Te4 evident from the Hall Effect measurements as well as also fromSdH oscillations. The surface states sustains even after doped with magnetic impurity. For dopedspecimens the signature of the elongated band outside the surface Fermi surface are not observed andis consistent with the reported ARPES measurements. E-k diagram made from SdH oscillations ofdifferent doping percentage in PbBi2Te4 corroborates linear Dirac dispersion nature of the surfacestates, inherent to topological insulators.

Mr KIRAN TImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Central University of Tamil Nadu


Abstract: Shortcuts To Adiabaticity (STA) protocols are nonadiabatic processes that reproduce in finite time the same initial and final states as that of an infinitely slow adiabatic process1. These protocols can be used as an alternate driving of the system to implement the adiabatic process. We investigate the single spin quantum systems using different methods of STA and design quantum engines with spin in quantum systems as a working medium to study its characteristics including cost of implementation. Comparison of different methods such as Counter-Diabatic (CD) driving2,3, Invariant based Inverse Engineering (IE)4 and Local Counter-Diabatic5 (LCD) would help us to determine an efficient method with less cost of implementation. Our study will also discuss the adiabaticity factor and work obtained from each of the above methods for differentiating their merits and demerits for the purpose of quantum engines.

References:

1. Erik Torrontegui, Sara Ib_a~nez, So_a Mart__nez-Garaot, Michele Modugno, Adolfo del Campo, David Gu_ery- Odelin, Andreas Ruschhaupt, Xi Chen, J. G. Muga. Advances in atomic, molecular and optical physics 62, 2013 117169. 2. Adolfo del Campo Phys. Rev. Lett. 111, 2013 100502. 3. Bar?s Çakmak and Özgür E. Müstecapl?o?glu Phys. Rev. E 99, 2019 032108. 4. H. R. Lewis and W. B. Riesenfeld J. Math. Phys. 10, 1969 1458. 5. Adolfo del Campo and Kihwan Kim New J. Phys. 21, 2019 050201.

Ms PRITI NAYEKImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : NATIONAL

INSTITUTE OF TECHNOLOGY DURGAPURDesignation : RESEARCH

SCHOLAR

The standard model (SM) of particle physics has been a spectacularly successful theory forexplaining the properties and interaction of fundamental particles with many measurements confirmingits prediction to an extra ordinary precision. But from several experiments it has been observedthat the rare B decays which arise from one loop diagram in the SM are suppressed in comparison totree level diagram. A detailed investigation on the results of branching ratio of rare B mesondecays which are mediated by flavor changing neutral current (FCNC) transitions is the auspiciousway to explore the new physics (NP). Some of NP models are: the models with extra Z? boson and/oradditional Higgs doublets, model with lepto-quarks etc. Z? model is one of the most importanttheoretically constructed model to understand physics beyond the SM. Z' gauge bosons are predictedby a wide variety of extensions of the SM. Since the Z' boson is not discovered so far, its exactmass is unknown. More analyses are needed to assess the actual nature of this boson. Now a dayssemileptonic B meson decays induced by flavour changing neutral current transitions (FCNC) as wellas the baryonic decays are very important to probe the quark-flavour sector of the SM and also offera probe to test NP. So I am interested to study such semileptonic B meson decays and baryonic decaysin a non-universal Z' model.

Ms Shelma GeorgeImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Vimal Jyothi

Engineering CollegeDesignation : Assistant

Professor

Hybrid vehicle is the one in which two or more energy sources or converter provides the requiredtraction power to the transmission. Hybrid Vehicle are enjoying more widespread customer acceptanceas personal vehicle because of their performance and economy in running cost. Normally in parallelhybrid vehicles, electric machines are using in parallel with conventional Internal CombustionEngine. Torque from the electric machine is added to the torque from the ICE and the total torque ispropelling the vehicle. In this paper the various architectures of parallel hybrid are presented.Modes of operation and power flow diagram in each case is analysed and the control method is alsostated.

Mr prathap somaImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : NIT Warangal


The Border Security Force (BSF) is the primary border guarding force of India. it is one of the fiveCentral Armed Police Forces of the Union of India. Usually, Border Security Force soldier looksthrough binoculars along the India-Pakistan border because of haze they lose their ability to lookat the surroundings. However fog-degraded images clearness is a challenging task, especially rapiddefogging on a single image for its application in the moving systems. As depth informationdependent on the quantum of fog in the atmosphere is unknown and hence acquisition for the depth ofa single two dimensions image is an unconstrained problem. Therefore, it is necessary to make rapiddefog on a single image, which can improve the reliability of all kinds of the outdoor vision systemin foggy weather. We implemented a method for removing the fog from a single image using the darkchannel prior method (DCM). The DCM is adopted based on statistical data of the outdoor images whichare haze-free. Based on the information from the DCM on hazy images, the thickness of haze isestimated. Thereby, a haze-free of a high-quality image is recovered. These image processingalgorithms are most preferably implemented on Field Programmable Gate Arrays (FPGA’s) as they arereprogrammable to perform required operations. This abstract describes the implementation of theSingle Image Dehazing Technique on Zynq-706 board which consists of ARM cortexA9 processor alongwith FPGA’s. To implement this, Intellectual property (IP) cores are used, these IP cores arebrought down to vivado 2015.4 to create the required hardware. Finally, the design was programmedinto Zynq FPGA. The software application is developed using the Software Development Kit (SDK). Theresults are obtained for an image size of 1080x1920.

Mr VENKATESH THOORPATIImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : KU


The main objective of every electrical engineer is to provide uninterruptable power supply to thecustomers (loads). Since two century’s Electricity is playing a vital or prominent role in rapidindustrialization, Urbanization and Socio-economy. Without electricity, the modern society cannotrun its daily life because most of the essential services like hospitals, Nursing homes, airports,railways, irrigation, gas, communication and internet services require the electrical supply as acritical need. Major power disturbances or outages or blackouts are caused by a variety ofinitiating events. Even though most of the power systems are equipped with sophisticated EMS/SCADAsystems and automatic devices, it cannot prevent the occurrence of a system blackout or poweroutage, though rarely happen, which may cause heavy damage to the economical and social life. Due toPower failures some times in power system network degrades the performance of the industry. Thesepower failures are occurred mainly due to island formations or blackouts resulting from significantloss of generation or bulk power transmission.

Ms Raksshitha NJImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Sri

Sivasubramaniya Nadar college of engineering


It is known that 70% of the earth is composed of water bodies. Through various researches are being undergone for many applications like wireless communications, disaster detection, submarines, autonomous under the vehicle, pollution monitoring, manned and unmanned remotely operable underwater vehicle, exploration of natural resources, etc the unexplored treasures are yet to be discovered. The remotely operated vehicle comes to rescue here. ROV transport us across ocean waters and into various depths even in zero visibility, allowing us to examine, explore and analyze the mysteries of the ocean. An underwater robot, termed as Remotely Operated Vehicle (ROV) simplifies our job, by being able to reach difficult underwater areas and swamps. As a part of any mobile robotic system, some means of locomotion is necessary in order to move the robotic system. For that reason, thrusters are used for the movement of the ROV. This project aims at developing a thruster architecture to enable the movement of the ROV. Depending on the thrust vectoring algorithm, thruster configuration is finalized to achieve the six degrees of freedom. Thrusters are a critical design consideration for any ROV system. Without having the proper thrust, the ROV can be overwhelmed by the environmental conditions and thus unable to perform the desired tasks. Thrusters can be either electrical, hydraulic, ducted jet type or a combination of those four. But this project aims at developing ROV using BLDC motors for propulsion and control them using PMW.

ROVs simplify the inspection task to the greatest extent thereby increasing its demand lately. Therefore, it is very essential to develop efficient thruster architecture. In this project, the problems associated with maneuvering the ROV in the high oceanic environment is addressed and a solution to make the motor mounts in the most efficient way is proposed.

Mr Nitesh NarwadeImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : GH raisoni

college of engineering nagpurDesignation : student

CHARGING OF MOBILE AND LAPTOPS WITH RADIATION ENERGY Author’s Name: Nitesh Naresh Narwade Contact:7798543844 , 9309830817 Email:[email protected]

Abstract: We know that in our environment there is lots of radiation infect we people surrounding by the radiation . But this radiation is in so small amount but we can use this radiation as the energy sources to charge our very cheap devices such as the mobile phone and laptops . We know that the mobile towers are emits radiation and this radiation is present in the our atmosphere. This radiation consist of the electrons (charge carrier) If we are able to collect all this radiation (electrons) at the one metal plate the this metal plate becomes negatively charge and if we placed another metal plate beside it then this another metal plate act as the positively charge hence now the air between the these two plate act as the dielectric medium and the whole system act as the capacitor. We can stored the radiation energy in this capacitor from atmosphere and use this energy to charge small devices. References: 1) Basic Electrical book for capacitor .

Dr Ayush SaxenaImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Ramrao Adik

Institute of TechnologyDesignation : Associate

Professor

Magnetic signatures are induced in a naval vessel due to its exposure to the Earth’s magneticfield. The reduction of this magnetic signature or the remnant magnetic field is called asDegaussing. Every naval vessel has got a degaussing system which is meant to reduce the magneticsignature of the vessel, hence, prevents it from detection by both underwater and airbornesurveillance systems. In this paper, electromagnetic simulation of a naval vessel (submarine) isdone using COMSOL Multiphysics. Electromagnetic simulations are used to estimate the inducedmagnetic signature of a naval vessel in the presence of earth's magnetic field. This inducedsignature is further reduced using arbitrary placement of degaussing coils in the three spatialdirections (vertical, athwartship and longitudinal). The current in the degaussing coils iscalculated using Nelder-Mead optimization, which resulted in a signature reduction of around 60%.Higher signature reduction can be achieved by using better placement and optimization techniques.

Ms Divya MImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Veermata

Jijabai Technological InstituteDesignation : Student(first

year- PhD)

Vision of National Smart Grid Mission of India is to transform power sector of our country into a secured, adaptive, sustainable and digitally enabled ecosystem. It also aims to provide reliable and quality energy for all with active participation of stakeholders. Power system consists of generating, transmitting and distribution system. Electrical distribution systems deliver electrical power from substations to consumers. They are the weakest links in electrical power system since almost 50% of system losses occur in distribution systems. Since the implementation of Electricity Act 2003, Indian power sector has conducted research and experiments in achieving smart distribution system.

In order to plan various activities of distribution system, analysis of consumption data of consumers are required. In this work, we have focused on identification of conforming loads of total substation data. Load curves that have similar shape of total substation load are known as conforming loads. They are useful inputs for demand response and demand side management. Classifications of customers as conforming and non-conforming are also useful for load forecasting, automatic generation control and load flow analysis.

In this work, we have proposed an optimization based method to identifying conforming loads. We have used Ant Colony Algorithm to solve the problem. It is a meta-heuristic algorithm that tries to emulate the behaviour of real ants by which they are able to identify the shortest path between a food source and their nest. Initializations were done based on difference method. The results obtained were verified for Smart Meter Energy Consumption Data in London Households. The proposed method was compared with statistical methods like correlation and least square regression methods. It was observed that in addition to exact conforming loads, our method gave similarity index for partially conforming loads too. Also the algorithm could incorporate various constraints and changes in loads.

Ms Shaik AsmaImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : GPCETDesignation : Student

Using diodes and piezo effect in rockets instead of fuel

* S . Asma *(b. tech student) email id: [email protected]

Fuel is used in rockets to launch a satellite , here fuel produces a lot of pollutants into atmosphere.To avoid this, we can use diodes and piezo electric effect material connected together to produce mechanical energy to lift a rocket. With this, atmospheric pollution is minimized and made eco friendly.

Mr Karamala Jayanth KumarImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Aditya college

of engineering madanapalleDesignation : B.tech

Wireless power transmission is the way to transfer power without using wire. Wireless power transmission helps to connect those area where people are unable to get a suitable power source. Everyone can get clean and efficient wireless power. In future all the devices will relate to the power supply source wirelessly. In this paper I would like to present the future scope of wireless power transmission and their application in our life. This wireless power transfer technology helps to transfer the power where wired power transmission is impossible. Now a day, we are using technology wirelessly like our phone, which is a very big example of it but if we implement this method to use modern technology by using wireless method then our communication will be strong and smooth. I would like to discuss about this wireless power transmission technology and it's various applications in our life.

Mr BHANU PRAKASHImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : ADITYA

COLLEGE OF ENGINEERINGDesignation : STUDENT(FINAL

YEAR)

Wireless power transmission is the way to transfer power without using wire. Wireless powertransmission helps to connect those area where people are unable to get a suitable power source.Everyone can get clean and efficient wireless power. In future all the devices will relate powersupply source wirelessly. In this paper I would like to to present the future scope of wirelesspower transmission and their application in our life. Is wireless power transfer Technology helps totransfer the power where wired power transmission is impossible.

Ms Hemu FarooqImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Bhagwant

University, Ajmir Raj.Designation : PhD. Scholar

A Novel Assisted Sleep Scoring System and stages using Artificial Neural Network

Hemu Farooq1*, Anuj Jain1, Sheikh Mohammed Idrees1, Ajaz Ahmad Reshi3, V.K. Sharma1 1Department of Electronics and Communication Engineering, Bhagwant University, Sikar Road, Ajmer, Rajasthan, India- pin code 1Department of computer Science and Engineering, School of Engineering Science and Technology, Hamdard University, Hmadard Nagar, New Delhi, India-110062 1 Department of Computer Science, College of Computer Science and Engineering, Taibah University, Al Madinah Al Munawarah, Saudi Arabia-42353

Abstract Sleep analysis and its categories in sleep scoring system is considered to be helpful in the field of sleep medicine and research. The proposed study employs a novel computer assisted automatic sleep scoring system using Artificial Neural Network and physiological signals. The data collected were recorded for seven hour, 30 second epoch for each subject. The features extracted were trained and classified using an Artificial Neural Network classifier. Even though, ANN is a highly complicated concept, using same in biomedical field is novel when it is employed with electrical signals acquired from body. The accuracy estimated for the system was found to be good and thus the method can be applied in clinics, particularly helpful for neurologist for diagnosing the sleep disorders.

Key Words: Sleep Scoring stages, EEG, EMG, EOG, Artificial Neural Network

Ms Debadyuti BanerjeeImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Modern

Institute of Engineering & Technology


Electric vehicles (EV) are gaining popularity over conventional automobile vehicles for the advantages of zero pollutant emissions, high energy efficiency and provision of regenerative braking. EVs use a battery bank containing series-parallel combination of several small units to meet the high power demand of the drive system. Conventional lead acid battery banks constitute a great proportion of the entire EV in terms of size, weight and foot print requirement. Sincere efforts are therefore being made by EV manufacturers to use lithium-ion storage systems with reduced size, weight and space requirement. The other advantages with the Li-ion batteries are higher cell voltage (average of 3.7 V), no memory effect, low self-discharge rate (less than 20% per year) and longer battery life. In a battery pack with many series connected cells, individual cell voltages may not always be equal for the reasons of state of charge (SOC) imbalances and the differences in their internal resistances. Thus, at charging, before few cells get incomplete charged, others may sometimes get overcharged. If the maximum charging voltage of a Li-ion cell exceeds over 4.2 V, the cell life gets reduced considerably. During discharging, if voltage of one cell goes below the minimum permissible threshold, discharge of the whole pack is required to be stopped to prevent the weak cell and also the pack from getting damaged, although other cells still have stored energy. These two effects ultimately results in under utilization of the battery pack. In order to mitigate these problems, external power balancing circuits are used to remove the voltage differences. In passive cell balancing, the excess charge of a cell with higher SOC is dissipated across resistors in the form of heat. In active cell balancing system, the excess charge of a cell with higher SOC is efficiently transferred to other cells with the help of power electronic converters and a high speed controller. In this work, an active circuit is proposed for charge balancing of a Li-ion battery pack. The proposed circuit uses a multi-winding flyback converter and n+1 number of active switches for a stack with n number of series connected cells. Performance of the proposed system has been verified through computer simulation in MATLAB with a 4 cell battery pack. Simulated results were found in close agreement with the predicted behaviour of the system.

Mr Narasimhulu PImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Defence

Research & Development Organisation

Designation : Scientist

Introduction: With the rapid development of advanced data transmission technologies in avionics fields, the avionics buses for future Avionic applications will have to cater to increased bandwidths to enable the high data transfer rate between sub-systems and the On-Board Computer (OBC). Major subsystems include INS, Seeker, Target Update Receiver, Warhead, Telemetry, and GPS. Typical data rates are of the order of 1 kHz to 1MHz. OBC has to acquire the data from these sub-systems and carry out the required computation in Real-time with periodicities of the order of 2.5ms / 5ms with deadlines of the order of 1ms. Safety-critical systems like aircraft, launch vehicles and satellites require a reliable communication protocol to guarantee their functioning without errors. Thus AFDX (Avionics Full Duplex Switched Ethernet) shows great potential in onboard avionic systems because of its high bandwidth, deterministic and redundancy property. In this paper, we introduce the design of High-Speed communication interface for Avionic applications, designed and developed based on ARINC664-P7 standard. It is a dual-redundant Ethernet Physical layer-based 100 Mbps network. The AFDX infrastructure consists of End System (ES), Switch and Links. The main function of an End-System is to provide an interface to the avionics subsystem to send and receive data from the AFDX network. Each ES has two channels, one is main and another channel is redundant, same data is sent and received on both the links. The switch is responsible for switching the packets from one ES to another ES. The Links are the Ethernet cables connected in the network. The ES design is realized in the form of an IP (Intellectual Property) core and implemented on FPGA. This article covers the detailed design and implementation of the End System IP core. Design Approach: End System design is an IP core implemented using VHDL that converts data received from the subsystem (processor) into the protocol frames and transmits it using two redundant Ethernet ports. It receives data packets on both of its Ethernet ports from the switch and performs integrity and redundancy checks and stores for further processing. This interface enables various avionic subsystems to communicate with each other using the AFDX protocol. It offloads the processor by handling transmitter scheduling, converts data to AFDX protocol frames and sends it to the AFDX Interconnect for routing. It extracts data from incoming frames received from the AFDX Interconnect and sends it to the subsystem.

Mr SIVAGAMA SUNDARI M SImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : Amrita

College of Engineering and Technology, Nagercoil


Harmonic minimization of Cascaded H-Bridge Multilevel Inverter using SHEPWM Sivagama Sundari M S1*, & Selvaperumal S2 1Department of Electrical and Electronics Engineering, Amrita College of Engineering & Technology, Nagercoil, Tamilnadu, India-629901. 2Department of Electrical and Electronics Engineering, Syed Ammal Engineering College, Ramanathapuram, Tamilnadu, India-623502. [email protected]

Abstract: Photovoltaic energy conversion becomes main focus of many researches due to its promising potential as source for future electricity and has many advantages than the other alternative energy sources like wind, solar, ocean, biomass, geothermal etc. In Photovoltaic power generation multilevel inverters play a vital role in power conversion. Multilevel Inverter is a power electronic device that synthesizes a desired output voltage from several levels of DC voltages as inputs. The three different topologies, diode-clamped (neutral-point clamped) inverter, capacitor-clamped (flying capacitor) inverter and cascaded h-bridge multilevel inverter are widely used in these multilevel inverters. Among the three topologies, cascaded H-bridge multilevel inverter is more suitable for photovoltaic applications since each pv array can act as a separate dc source for each h-bridge module. In this paper, a single phase cascaded H-bridge eleven level inverter for grid connected photovoltaic system using particle swarm optimization (PSO) algorithm is presented. In selective harmonic elimination pulse width modulation (SHWPWM), given a desired fundamental voltage and for the elimination of m-1 harmonics, the switching angles corresponding to the above objective are obtained by solving a set of non-linear algebraic transcendental equations. PSO algorithm is applied to CHB eleven level inverter for solving the non-linear objective function and finding out the optimal switching angles for the switches. This proposed technique uses an automatic sequential scheme such that the total energy delivered charging level of the batteries and terminal voltages are equal in all the DC sources. A MATLAB Simulink platform is used for optimization and compares the fall in charging level of the batteries and its effect on the mitigation of a selected harmonics with and without sequential rotation of the power sources. The prototype model has been developed by employing LPC 2148 ARM processor and the observations validated that the proposed idea eliminated the 5th, 7th, 11th and 13th order harmonics.

References: 1. Yu, Y.; Konstantinou, G.; Hredzak, B.; Agelidis, VG. IEEE Trans. on Power Elec. 2016, 31(2), 1108 – 1120. 2. Elena, V.; Pablo, C.; Jose, R.; Marion, P. IEEE Trans. on Power Elec. 2009, 56(11), 4399– 4406.

Mr BIPIN JAISWALImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : NATIONAL INFORMATICS CENTRE

Designation : ENGINEER

Abstract: After producing electricity, sometimes it becomes a great problem to supply it universally, specially in the areas not furnished with easily accessible transportation facilities. But fortunately, I have made the invention that proves infallibly that electricity can be supplied anywhere concerned wirelessly. I have named the device “Electricity Broadcasting.” A transmitter will be connected with the power station. Thereafter the transmitter will generate electromagnetic waves which will be decoded by the receiver connected with the load or user. The device is intended to successfully supply electricity wirelessly with the help of electromagnetic waves. In this innovation electromagnetic waves are used as the medium of electricity transmission from energy sources (power stations) to loads (users). The successful implementation of the device is indelibly intended to finish many of the problems related to electricity transmission. The efficacious utilization of the device will lead to the exclusion of Pillars/Poles uses, wires and cables uses and other so many pieces of equipment related to the present system of electricity transmission. Thus, the device concerned is sure to prevent strongly the wastage of so much money, time, energy spent on the present system of electricity transmission. It is a scientifically well known fact that electromagnetic waves have unlimited energy in themselves. So on implementing the device for the intended objects, the applicant will proceed further to find out other beneficial utilization of the electromagnetic waves. The applicant has designed the device as a prototype just to prove the hypothesis but the applicant is entirely dedicated to design the device on broad spectrum to bring revolution in the field of electricity Broadcasting. The applicant is continuously engaged in bringing the device on broad platform. I modestly do promise to bring unexpectedly alleviating revolution in the field of electricity broadcasting on being recognized and recommended.

Mr Jailsingh BhookyaImage Delegate ID Theme Details


Research

Category : ElectricalOrganisation : NIT Warangal


Agriculture automation is a major concern and an evolving challenge for every country. The worldpopulation is growing at a very rapid rate and the need for food rises dramatically with an increasein population. This influences the rural practice a ton and at last the land stays fruitless with nofruitfulness. This paper discusses distinctive robotization practices like IOT, WirelessCommunications, Machine learning and Artificial Intelligence, Deep learning. There are a few regionswhich are making the issues agribusiness field like yield maladies, absence of capacity the board,pesticide control, weed the executives and this issues can be tackled by precise robots ine-agriculture with intelligent control of robots. In this context, use of latest technologicalsolutions to make farming more efficient, remains one of the greatest imperatives. The structure ofproposed controller comprises of non-linear hyperbolic function of instantaneous error and currentstate cascaded with Fractional Order PID (FO-PID). Non-linear function provides adaptive controlability while incorporation of fractional operator enhances flexibility of designed controller. Toexamine the comparative merits of NLFPID controller, Non-linear PID (NL-PID), FO-PID and traditionalPID schemes are also implemented. Design variables of controllers are optimally tuned using multiobjective Non-dominated Sorting Genetic Algorithm II (NSGA-II) for small variation in control anderror signal. Results prove that NLF-PID provides robust and efficient control of robotic arm ascompared to other designed controllers for reference tracking, model uncertainty, disturbance andnoise due to inherent shortcoming of sensor.

Mr BIDYUT SARKARImage Delegate ID Theme Details


Research



Scholar

Magnetocaloric effect and order of Phase transition in electron doped Gd0.15Ca0.85Mno3. Abstract : Magnetic Phase transition and magnetocaloric effects have been studied in details. The target sample was synthesised by solid state reaction method. A paramagnetic (PM) to ferromagnetic (FM) phase transition is observed with transition temperature Tc=113K which is confirmed from the minimum of dM/dT vs T plot (e.g., [1]). Effect of Gd doping in Ca site breaks the long range antiferromagnetic ordering of parent CaMnO3 and ferromagnetism is formed. A small bifurcation arises between field cooled (FC) and zero field cooled (ZFC) magnetization under low applied magnetic field below Tc because of inhomogeneous mixture of FM and cluster glass-like phase (e.g., [2]). Below Tc the field dependent magnetization (M-H) curve shows the characteristic of ferromagnetic material and above Tc M-H curve shows nearly linear behaviour. Simultaneously, it also shows that magnetization does not saturate within 0-3T field range, this might be cause of some antiferromagnetic phase (AFM) in CGMO. Arrott plots suggest that there is a 2nd order phase transition and for further confirmation Landau coefficients gives the clarification of 2nd order phase transition. The Landau equation is written as H/M= a(T)+ b(T) M2+ c(T) M4 where a(T), b(T), c(T) are Landau coefficients [shown in fig2]. Griffiths Phase inhomogeneity is observed from inverse susceptibility curve deviates from curie-Weiss (CW) fit. Observed Griffiths Phase Temperature (TG) is 200K. In addition magnetocaloric effect has been measured for the field range 0-50KOe. Temperature dependent entropy changes have been determined using numerical Maxwell’s relation for different magnetic field. The maximum entropy change obtained 2.525 J.kg ? 1k – 1 for the maximum field change 50KOe. The positive intent we get from M-H data that hysteresis is very low which give the potential of MCE for CGMO.

Ms RINKU SARKARImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : University Of


Scholar

Structural, optical and magnetic properties of monovalent doped polycrystalline sample Gd0.85Li0.15MnO3 are reported here. Sample was synthesized in the air by conventional solid-state reaction method. Structural characterization of the sample was examined by using powder X-ray diffraction. Well fitted Rietveld refinement of the XRD data using the FULLPROF program assures that the sample possesses impurity phase free, single phased, orthorhombic structured (with Pbnm space group) crystal. Optical properties have been investigated by UV-absorption spectra. The room temperature UV-absorption spectrum using Tauc’s formula gives an optical band gap ?3.12eV. In the sample antiferromagnetic super-exchange interactions are observed in Gd3+-Gd3+, Mn3+-Mn3+, Gd3+-Mn3+interactions. Among them, Mn3+-Mn3+ interaction is more significant than the other two interactions since 3d-3d interaction is stronger than 4f-4f/3d-4f interactions. So antiferromagnetic behavior is observed in this sample below 42K. 15% Li substitution transforms 30% Mn3+into Mn4+ which enhanced the hole density, as a result, Zener double exchange mechanism in Mn3+-O-Mn4+network comes into play. Due to this weak ferromagnetism, canted antiferromagnetic ordering is observed below 21K.So the sample undergoes a transition from paramagnetic (PM) state to incommensurate antiferromagnetic (ICAFM) state below TN ?42K and transforms into a canted antiferromagnetic (cAFM) state below TC ?21K A ferromagnetic like M-H loop is observed at 5K and no saturation in the magnetization value in the whole range of the applied magnetic field (H) indicates the presence of canted antiferromagnetic states. Magnetic hysteresis curve at 5K signifies the Gd spin ordering. The coercivity of the sample is ?655 emu/gm and retentivity of the sample is ?7.41 Oe.

Ms Amrita MukherjeeImage Delegate ID Theme Details


Research


KalyaniDesignation : DST- INSPIRE

SRF

A uniform, out-of-plane electric field, applied to a periodic network of connected rhombii, mimicking a spintronic device, is shown to exhibit an intriguing, spin selective, extreme localization for particles with half-odd integer spin s> nh/4.pi, n= 1, 3, 5,... and for them the topological edge states always appear at E= ±root(2). The spectra for integral spins, as a whole, never show a complete collapse. Hence, ‘extreme’ localization is ruled out for integer spins, though the topological edge states show up for such spins as well. The phenomenon, reminiscent of Aharonov-Bohm caging for electrons, is induced through a topological Aharonov-Casher phase acquired by the travelling spin through a Rashba spin orbit coupling generated by an external electric field. Compact optical modes, exactly in the spirit of the compact localized flat-band states in the electronic case were also observed and these observations open up a new possible direction towards topological photonics. A complete collapse of the spectral landscape, seen to happen only for half-odd integer spin is triggered at a special strength of the spin-orbit coupling. The event is analyzed and explained analytically and supported by exact numerical results for spectral and transport properties. The observation finds an exciting experimental parallel in recent experiments unravelling caged, extreme localized states in photonic lattice analogues to the present system.

Mr SAIKAT NANDIImage Delegate ID Theme Details


Research


KalyaniDesignation : Senior

Research Fellow

We have extensively studied magnetic and heat capacity properties of a pyrochlore Gd2FeSbO7 in the light of cooperative two-sublattice model taking account of nearest-neighbour intra-sublattice (Gd-Gd and Fe-Fe) and inter-sublattice (Gd-Fe) magnetic interactions. Magnetic susceptibility of polycrystalline sample of frustrated pyrochlore Gd2FeSbO7 was measured between 350-2 K at the external field 0.1 T and 1T. A small bifurcation has been observed between FC and ZFC susceptibility measured at the external field 0.1 T below T ~10 K, indicating ferromagnetic ordering due to M-site Fe3+ ions [1]. A linear fit of inverse susceptibility in the paramagnetic region (15 K References: 1. Nandi, S; Jana, Y.M.; Swarnakar, D.; Alam, J.; Bag, P.; Nath, R.; Journal of Alloys and Compounds 2017, 714, 318-330.

Mr ANKIT GUPTAImage Delegate ID Theme Details


Research


Lucknow, University of Lucknow


Synthesis & characterization of Zinc Oxide (ZnO) doped Polyaniline

Ankit Gupta*, Mahendra Kumar** *Research Scholar, Department of Physics, University of Lucknow, Lucknow (U.P.) - 226007 ** Assistant Professor Email: [email protected]

Abstract: ZnO doped Polyaniline and Polyaniline thin films were synthesized by using Spin coating technique where Zinc Oxide was used as a base material. NMP was used in preparation of Polyaniline in acidic medium and ammonium persulphate as oxidizing agent. Thin films were deposited on glass substrate after cleaning in Ultrasonic cleaner. Further, structural and optical properties were investigated by X-ray Diffraction (XRD) technique and optical study was done with the help of UV-Visible Spectrophotometer (UV JASCO V-670). By XRD, it is found that change in the value of lattice parameter of Zinc Oxide and presence of interaction between matrix and ZnO particle. When compare to pure PANI and Zinc Oxide doped PANI, the FTIR study shows shift to higher wave number. A comparative study was done between pure PANI and Zinc Doped PANI as both showing different behaviour.

References: 1. K. Gopalakrishnan, S. Poonguzhali, Study on characterization and application of Polyaniline (PANI) and Fly ash composites, Journal of Chemical and Pharmaceutical Sciences, 2016, 9, 273-275. 2. M. B. Wasu1 and A. R. Raut2, Synthesis and Characterization of Polyaniline Based Conducting Polymers, J. Chem. & Cheml. Sci., 2014, 2.90-97. 3. Crucho, C.I.C.; Barros, M.T. Polymeric nanoparticles: A study on the preparation variables and characterization methods. Mater. Sci. Eng. C 2017, 80, 771–784. 4. Mirmohseni A, Solhjo. Preparation and characterization of aqueous polyaniline battery using a modified polaniline electrode. Eur. Polym, J. 2003; 39(2):219-23.

Ms DEBASMITA CHAKRABORTYImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : UNIVERSITY

OF KALYANIDesignation : Ph.D.

SCHOLAR

MAGNETIC FIELD INDUCED SPLITTING OF CRYSTAL FIELD LEVELS AND DC MAGNETISATION CALCULATION OF THE DOUBLE PEROVSKITES Ba2RSbO6 (R =Dy, Er) Debasmita Chakraborty*, Y.M.Jana Department of Physics, University of Kalyani, Kalyani-741235, Nadia, West Bengal, India [email protected]

Abstract: In the rare-earth double perovskite A2BB’O6, the B3+ ions form a face-centered cubic lattice. When B site is occupied by magnetic rare-earth ions, topological geometry of B-site sublattice frustrates near-neighbor antiferromagnetic coupling. We present here a systematic theoretical study of the double perovskites Ba2RSbO6 (R =Dy, Er) for magnetic susceptibility, dc magnetization and Zeeman splitting of the different crystal-field levels. Our calculations are interpreted by crystal-field theory for cubic Fm3m site symmetry at R-site by using Steven’s operator equivalent method. Our investigation indicates that Ba2DySbO6 is an example of doublet crystal-field (CF) ground state, with several degenerate excited states and Ba2ErSbO6 is with a quadruplet CF ground state. The external applied field removes the degeneracy of the CF levels causing admixture of the states which changes the magnetic properties of the samples.

References: [1]: S.Calder et al., J.Phys.Condens.Matter 22, 116007 (2010)

Mr Devansh DesaiImage Delegate ID Theme Details


Research


Physics, Gujarat University, Ahmedabad 380009

Designation : Ph.D. student

In this present study, we have developed new net radiation and soil heat flux models which werecoupled with STIC1.2 for large-scale applications. The integration of these net radiation and soilheat flux models into existing STIC model addressed some of the constraints that previously hinderedthe direct use STIC model for estimating H and LE on spatial scale. The present model uses 8-dayInsolation (INSAT-3D), 8-day LST (MODIS), 16-day composite Albedo (MODIS), 16-day composite NDVI(MODIS) and air temperature & humidity from Weather Research & Forecasting Model (WRF) as inputs.The challenge comes under cloudy skies conditions due non-availability of LST. In order to overcomethis challenge LST-NDVI relation was used to gap fill LST under cloudy sky conditions. An initialevaluation of this model over a variety of agro ecosystems showed encouraging results. The error insimulated daily ET was found in the range of 12-18% (0.35 – 0.5 mmd-1) across diverseagroecosystems on spatial scale during 2018-19. These Preliminary analyses revealed the potential ofour developed model to derive largescale ET using current Indian Geostationary satellite (e.g.INSAT) observations as well as future high resolution global thermal IR observations.

Mr Aquil AhmadImage Delegate ID Theme Details


Research


Institute of Technology (IIT), Kharagpur


Heusler alloys (HAs) are materials of interest of the scientific community for decades. The HAsfamily comprises three subfamilies: the half Heusler alloys, the full-Heusler (L21structure) alloys,and the inverse Heusler (XA structure) alloys. The subfamilies of HAs are well described somewhereelse [1]. They showed the diverse physical properties such as half-metallicity, superconductivity,shape memory effect induced by the magnetic field and the magnetocaloric effect [2, 3]. Thegeneralized gradient approximation (GGA) scheme in the first-principles calculations is used tostudy the effect of L21 and XA ordering on the phase stability, half-metallicity and magnetism ofCo2FeAl (CFA) Heusler alloy. Various possible hypothetical structures:L21-I, L21-II, XA-I, andXA-II are prepared under the conventional L21 and inverse XA phases by altering the atomicoccupancies at their Wyckoff sites. It is found that the XA-II phase of CFA is the most stable phaseenergetically among all the structures. The electronic structure calculations without U, show thepresence of half-metallic (HM) ground state only in L21-I structure and the other structures arefound to be metallic. However, the electronic structures of CFA are significantly modified in thepresence of U, although the total magnetic moments per cell remained the same and consistent withthe Slater-Pauling (SP) rule. The metallic ground states of CFA in L21-II and XA-II structures areconverted into the half-metallic ground states in presence of U but remained the same (metallic) inXA-I structure. The results indicate that the electronic structures are not only dependent ontheL21and XA ordering of the atoms but also depend on the choice of U values. So experiments may onlyverify the superiority of GGA+U to GGA

Mr Arindam kumar chatterjeeImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Gurukul

Kangri ViswavidalayaDesignation : PhD student

In the present paper, we have explored various gravitational aspects such as energy extraction,particle collision around a dyonic rotating black hole spacetime in N=2, U(1)^2 gauged supergravity.The impact parameter of the rotation parameter and the gauge coupling constant on the behaviour ofhorizon and ergoregion of the black hole is studied. The energy extraction mechanism via Penroseprocess and superradiant modes is also presented numerically for the black hole. Interestingly, ourresult indicates that for a strongly coupled extremal black hole under certain constraint, themaximum efficiency for this case becomes almost double while compared with the case of extremal Kerrblack hole spacetime in general relativity (GR). Under the same constraint, the maximum amount canbe extracted from an extreme black hole which increases with respect to the coupling constant andcomes to have an upper bound which is 60.75% of its total energy. The limit of energy extraction interms of the local speeds of the fragments is also examined with the help of the Wald inequality.We identify an upper limit on the gauge coupling constant up to which the phenomenon ofSuperradiance is likely to occur. The energy for the collision of two particles having equal restmass accelerated by the black hole spacetime in the center-of-mass (CM) frame is also calculated.Our study also aims to sensitize the CM energy to the rotation parameter and the gauge couplingconstant for both extremal and nonextremal black hole spacetimes. For the extremal spacetime, aninfinitely large amount of CM energy can be achieved closer to the horizon which allows the N=2,gauged super gravity dyonic black hole to serve as a more powerful Planck-energy-scale collider ascompared to Kerr and any other generalized Kerr black hole explored so far in GR.

Ms Anju DahiyaImage Delegate ID Theme Details


Research


DelhiDesignation : Ph.D student

We present the thermodynamic properties described by a model of magnetic potential term introduced in Polyakov-Nambu-Jona-Lasinio (PNJL) model for two flavor quark at finite temperature. By the presence of magnetic field term in the potential, the result of thermodynamic properties are improved for the results produced by unmagnetized model of Ratti et al.

Ms ANJALI CHAUDHARYImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : IIT Indore


Polythiophene-PCBM-Based All-Organic Electrochromic Device: Fast and Flexible Anjali Chaudhary, Rajesh Kumar* Material Research Laboratory, Discipline of Physics, Indian Institute of Technology Indore, Simrol-453552, India Author e-mail: [email protected] A fast and flexible all-organic electrochromic device, fabricated using polythiophene and PCBM as active materials has been reported here. The device shows quantifiable improvement in electrochromic performance using parameters like switching speed, coloration efficiency, color contrast, and cycle life. Spectroscopic investigations have been carried out using Raman and UV-vis to establish a bias induced redox switching based mechanism for reported improvement in the performance. An enhanced stability for duration of longer than 2500 s and 250 cycles has been reported with an ultrafast response of few hundred milliseconds. A very high coloration efficiency of 321 cm2/C is achieved, making the proposed device one of the best reported P3HT-based electrochromic devices.When device is unbiased, the “initial” state (red curve), maximum absorption is observed in the vicinity of 550 nm indicating the absorption of green color (appearing magenta) in the transmitted light responsible for the magenta appearance to device. At 1 V bias (black curve), the absorbance decreases and all the wavelengths very poorly gets absorbed almost equally making the device appear transparent to the visible spectrum. On bias reversal (-1V) the magenta color gets reinstalled as evident from the increase in the absorption back in the green region mimicking the same spectrum as that of the unbiased device. The device shows more than 50 % color contrast corresponding to 550 nm when switched between magenta and transparent states. References: 1. J. Mortimer, R. Electrochromic Materials. Chemical Society Reviews 1997, 26 (3), 147–156. 2. Chaudhary, A.; Pathak, D. K.; Mishra, S.; Yogi, P.; Sagdeo, P. R.; Kumar, R. Polythiophene -Viologen Bilayer for Electro-Trichromic Device. Solar Energy Materials and Solar Cells 2018, 188, 249–254.

Ms DUVVU LISSAImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Andhra

UniversityDesignation : DST-INSPIRE

JRF

Abstract: The main aim of the present study is to know the variation of total electron content (TEC)of ionosphere derived from GPS signals and GIM code TEC over ten low latitude stations distributedaround 80o E (Waltair and four IGS stations SGOC, IISC, HYDE, LCK4) and 120o E (Five IGS stationsSHAO, TCMS, CKSV, PIMO, PGEN) longitudes in the northern hemisphere during 26 August 2018geomagnetic storm. During the main phase of the storm, SYM-H index is reached to a minimum of -206nT at 07:11 UT, the KP index is raised to 7.3 and the solar wind velocity is 400 km/s. Largepositive storm effect was observed during the storm period over all the stations distributed overboth the longitudes. The enhancement in TEC is observed during the recovery phase irrespective atboth the longitudes. While there is a decrement in TEC is evidenced only for the stations well above20° N geographic latitudes and positive storm effect is observed for the stations below 20° Ngeographic latitudes. The enhancement in TEC is more for the stations distributed around 80 ° Elongitudes compared to the stations those around 120° E longitude. The GIM code TEC variations overboth longitudes during the storm period further confirms the above said enhancement and decrement inTEC. The TEC in equatorial ionization anomaly (EIA) crest region is strongly enhanced during thestorm period. The stations around EIA crest show large positive storm effect compared to otherstations over both the longitudes. The positive storm effect is may be due to the main phase of thestorm falls on the day side over the above said longitudes, which further confirmed by the modelderived prompt penetration electric fields.

Dr Bhupendra Kumar TiwariImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : A.P.S.University

Designation : Guest Faculty

Abstract – The structure of the heliosphere controls by solar variability and produce changes in GCR intensity. The Changes in Galactic Cosmic Rays (GCRs) intensity for the ending period of the solar cycle 23 and the beginning of the solar cycle 24 using neutron monitors experimental data, we observed that an increase of the GCRs intensity is generally related with decrease of solar wind velocity Vsw ( Keywords-Interplanetary Magnetic Field (IMF), Galactic Cosmic Rays (GCRs), Solar Wind Velocity (SWV) Sunspot Number (SSN).

Mr SHIVENDRA TRIPATHIImage Delegate ID Theme Details


Research


OF LUCKNOWDesignation : RESEARCH

SCHOLAR

A Review Paper on Structural & Optical properties of Zinc Oxide (ZnO) Nanoparticles Shivendra Tripathi*, R.K Shukla** Research Scholar, Department of Physics, University of Lucknow, Lucknow (U.P.) – 226007 **Professor Email: [email protected] Abstract: The nanoparticles have continuously been analyzed and applied in many industrial applications for the decade. Nano-materials have been an essential research in applied science and engineering. Zinc oxide (ZnO) nanoparticles have received a remarkable consideration due to their extra ordinary UV filtering properties, photochemical antifungal, high catalytic and antibacterial activities. Zinc Oxide (ZnO) is a provocative material for applications in electronics, photonics, acoustics and sensing. Zinc Oxide nanoparticle is a unique material that exhibits itself as semiconductor and piezo-electricmaterial. In this paper, a modern review of Zinc Oxide nanostructure, its unique characteristics at nanoscale level and the properties is presented through an analytical process. The behaviour of Zinc Oxide at nanoscale is explored and its industrial application as a semiconductor, nanowire and other area of material science is presented. Finally, this review is concluded with many future scope and enhancement. References: 1. Laxmi Dangol and Leela Pradhan Joshi, Journal of Institute of Science and Technology (2016) 2. M. Lalanne, J. M. Soon, A. Barnabe, L. Presmanes, I.Pasquet and Ph. Tailhades, Journal of Materials Research, 25(2010) 3. H. Belkhalfa, H. Ayed, A. Hafdallah, M. S. Aida, R. TalaIghil, Optik, (2016) 4. 1. H.A. Wahab, A.A. Salama, et al.Optical, structural and morphological studies of ZnO nano-rod thin film using sol- gel., 3 (2013) 5. A.Hatamie, A. Khan, M. Golabi et al., “Zinc oxide nanostructure-modified textile and its application to biosensing, photocatalysis, and as antibacterial material,” Langmuir, vol. 31, no. 39, pp. 10913–10921, 2015 6. R. K. Das "Preparation of ZnO Nanorods by Hydrothermal Process at Different Temperatures." International Journal of Scientific Research in Physics and Applied Sciences 5.5 (2017).

Ms Moumita NaskarImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Presidency

University, KolkataDesignation : Ph.D. Student

Modification of Reversal Time of Magnetisation in Ising Ferromagnet by Random Impurities Moumita Naskar*, Muktish Acharyya Department of Physics, Presidency University, Kolkata-700073 Email address: [email protected]

Abstract: The magnetic reversal time of a ferromagnetic film plays the key role in the speed of recording. The high speed magnetic recording device is extremely important in modern technology (e.g. data storage). The main objective is to reduce the reversal time which produces faster recording. We review the reversal time of magnetisation in 2D Ising ferromagnet in the presence of externally applied uniform magnetic field by extensive Monte Carlo simulation based on Metropolis single spin flip algorithm. Then we investigate the change in reversal time in presence of quenched random field of 3 different distributions (Bimodal, Uniform and Gaussian distribution). It is observed that the reversal time decreases in presence of any kind of random fields and also varies with the nature of distribution of random fields. We also check whether the system obey Becker-Döring theory of classical nucleation in presence of random field and try to investigate the range of the width of the distribution of random field, beyond which the system fails to behave as prescribed by Becker-Döring theory.

References:

1. M. Acharyya and D. Stauffer, Eur. Phys. J. B, 1998, 5, 571-575. 2. M. Acharyya, Physica Scripta, 2010, 82, 065703. 3. M. Acharyya, Physica A, 2014, 403, 94-99. 4. A. Dhar and M. Acharyya, Commun. Theor. Phys., 2016, 66, 563. 5. R. Dutta, M. Acharyya and A Dhar, Heliyon, 2018, 4, e00892. 6. J. D. Gunton, M. Droz, Introduction to theory of Metastable and Unstable states, springer-verlag Berlin, 1983. 7. R. Becker and W. Döring, Ann. Phys. (Leipzig), 1935, 416, 719. 8. M. Naskar and M. Acharyya, cond-mat arXiv: 1908.09268.

Ms Sugarthi SrinivasanImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : SRM IST

Designation : PhD Research Scholar

Dye sensitized solar cell have considered as low cost and high efficiency solar cell. Counterelectrode is one of the most important components of DSSCs which is used to collect electrons fromthe external circuit to the redox electrolyte and catalyzes the reduction of triiodide to iodideions for the complete device performance. Most commonly used counter electrode is noble metalplatinum which has good stability and excellent catalytic activity. Since platinum is expensive, theresearch focused on alternative source for Pt free CE materials for cost effectiveness. The ternarycompound has more attention in the solar cells due to its high absorption coefficient, longphotoluminescence lifetime and tunable band gap adapted for efficient sunlight harvesting. Silverbismuth sulfide belongs to the group of I-V-VI semiconducting materials, which has high absorptioncoefficient of about 105 cm-1 with the standard band gap of ? 0.9 eV. In this work, the AgBiS2 hasbeen synthesized using solvothermal method with different wt% of rGO. The XRD pattern of AgBiS2 iswell matched with the JCPDS card no. 89-2045. The maximum intensity of reflection plane (2 0 0)indicates the growth direction of AgBiS2. FESEM micrograph shows the AgBiS2 has particle likemorphology. XPS analysis confirms the presence of the elements Ag, Bi, S, C. Further cyclicvoltammetry analysis will be analyzed.

Mr Arka ChatterjeeImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : S N Bose National Centre for Basic

SciencesDesignation : Senior

Research Fellow

The effect of different capping layers on the optical properties of self-assembled InAs quantum dot (QD) has been explicitly investigated and analyzed via temperature dependent photoluminescence (PL) and picosecond time resolved photoluminescence (TRPL) studies. The quaternary (In0.21Al0.21Ga0.58As) capped InAs QD has a room temperature PL peak near the communication wavelength (~ 1.3 µm), which is red-shifted compared to the ternary (In0.15Ga0.85As) and GaAs capped QDs. This can be attributed to the formation of larger dot size in the quaternary capped QD sample, due to the significant strain relaxation and reduced interdiffusion of In and Ga adatoms between the dot and capping material. The conduction band offset in the InAlGaAs capped QD has been calculated from the PL spectra, which is higher compared to the InGaAs and GaAs capped QDs.[1] The behavior of PL intensity with respect to temperature has also been studied in this article. The change in PL intensity and carrier lifetime has been observed minimum for the quaternary capped InAs QDs, which evince the minimization of carrier redistribution due to carrier-carrier or carrier-phonon scattering at even higher temperatures. This will provide temperature insensitivity at elevated temperature due to the higher barrier potential. We have also studied the dependence of PL lifetime at different detection energy.The QDs with different capping layers have different PL lifetime dependencies due to the variation in their size and the nature of carrier confinement. Hence, the optimum optical properties of the InAs QDs with different capping layer have been, elaborately studied, which can be very much helpful in device fabrication with these structures.

Dr Tamal SarkarImage Delegate ID Theme Details


Research


North BengalDesignation : Scientific

Research Officer-II

Neutron stars are remnants of supernovae explosion of massive stars 10 M? upto 20-40 M? at the timeof their formation, neutron stars gain recoil kicks due to asymmetries that develops during thecore-collapse process. Neutron stars are classified as Radio Loud and Radio Quiet. 1E 161348-5055.1is a radio quiet neutron star found in the Centre of RCW103 Supernova remnant and is a periodicX-Ray with a period of 6.67 hours. This source was discovered by the HEAO-2 (Einstein Observatory),which is the first fully imaging X-Ray telescope. This source attracted interest due to the two mainreasons. Firstly, its periodicity of 6.67 hrs which is too long for star having age 2000 years, itis behaving like a multi-million-year-old star. Secondly, the star becomes 50 times brighter inbetween October 1999 and January 2000. Astrophysicist put forward many theories to explain thisphenomenon. In the present work, we reviewed some of the papers relating the source and downloadedone archived data from XMM Newton and analyzed it to understand the nature of the neutron star 1E161348-5055.1.

Dr SENTHIL KANNAN KImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation :

EDAYATHANGUDY G S PILLAY ARTS AND SCIENCE COLLEGE

NAGAPATTINAM 611002 TN INDIA

Designation : DIRECTOR RESEARCH RESEARCH

SCIENTIST

2A44BP6M4HBC3C Crystals are having wide range of applications in opto electronic and phase matching and frequency doubling, it is monoclinic in nature with a is 6.0824 Å, b is 16.6919 Å, c is 17.7701 Å, beta is 93.64o. The chemical formula is C21H15N2O2Br, FTIR analysis specifies the vibrations at different functional groups in cm-1. By CHNSO analysis C, H, N, O and S elements are analysed in the titled specimen. As the crystals of 2A44BP6M4HBC3C are of NLO of second order, it can be having the influx proviso and beam displacement by filters are analysed and chromene derivatives are used for bio applications and here 2A44BP6M4HBC3C are used for anti-diabetic activities and from PL study the emission is 400 nm and respective band gap is 3.1020 eV.

Keywords: XRD, CHNSO, FTIR, 2A44BP6M4HBC3C Crystals …

Mr MD NUR HASANImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : S.N. Bose National Centre for Basic

SciencesDesignation : Junior

Research Fellow

Enhanced Water Stability and Photoresponsivity in Meal Organic Framework (MOF): A Potential Tool to Combat Drug-resistant Bacteria Md. Nur Hasan, [a] Samir Kumar Pal*, [a]

aDepartment of Chemical, Biological and Macromolecular Sciences, S. N. Bose National Centre for Basic Sciences, Block JD, Sector III, SaltLake, Kolkata 700 106, India

*Corresponding Authors Email: [email protected]

Abstract: In this work, we have successfully synthesized a bimetallic (Zinc and Cobalt) Zeolitic Imidazolate Framework (ZIF50)1, a class in a wider microporous Metal Organic Framework (MOF) family. The synthesized nanostructures maintain both water stability like ZIF8 (solely Zn containing) and charge transfer electronic band in the visible optical spectrum as ZIF67 (solely Co containing). Crystal structure from XRD, high resolution transmission electron microscopy (HRTEM) followed by elemental mapping (EDAX) confirm structural stability and omnipresence of the metal atoms (Zn and Co) across the nanomaterial with equal proportion. Existence of charge transfer state consistent with ZIF 67 and intact ultrafast excited state dynamics of the imidazolate moiety in both ZIF8 and ZIF67, are evidenced from steady state and picosecond resolved optical spectroscopy. The thermal and aqueous stabilities of ZIF50 are found to be better than ZIF67 but comparable to ZIF8 as evidenced from solubility, scanning electron microscopy (SEM) and XRD studies of the material in water. We have evaluated the photoinduced ROS generation by the mixed ZIF employing dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay. We have also explored the potentiality of the synthesized material for the alternate remediation of methicillin resistant Staphylococcus aureus (MRSA) infection through the photoinduced reactive oxygen species (ROS) generation and methylene blue (MB) degradation kinetics. References: 1 Binling Chen, Zhuxian Yang, Yanqiu Zhu, and Yongde Xia, 'Zeolitic Imidazolate Framework Materials: Recent Progress in Synthesis and Applications', Journal of Materials Chemistry A, 2 (2014), 16811-31.

Mr A SivakumarImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Sacred Heart

CollegeDesignation : Research

Scholar

It is well known that super-cooled materials can be crystallized under the application of shock waves. This is the first report describing crystallization from unsaturated liquids. Shock-wave-induced crystallization of salts from environmental ground and sea water samples is explored. A table-top pressure-driven shock tube is utilized so as to produce the required shock waves of Mach numbers 1.1, 1.2, 1.4, 2.2 and 4.7. The demonstration comprises a train of acoustic shock pulses applied to the water samples. As a consequence of the impact of the shock waves, the colorless water becomes turbid, following which tiny crystallites are precipitated at the bottom of the vessel after a few minutes. The obtained precipitate is subjected to powder X-ray diffraction and energy dispersive X-ray spectroscopy analysis to confirm the nature of the settled particles and the elements present in them, respectively. From the observed results, it is concluded that shock-wave-induced crystallization in water provides an alternative method for removing dissolved salts from both ground and sea water samples and Fig.1 shows the photograph of before and after shock wave application. Shock Wave induced Seed germination Shock waves are applied on the seeds of Amaranthus Aritis (Araikirai) with a Mach number of 1.5. Then the control seeds and shock wave treated seeds are cultivated. Same environment and water are supplied for both the control and shock treated plants. We observed very good growth rate for the shock treated seeds than the control seeds without adding any fertilizer. The photograph of the control and shock wave induced plants (after 28 days) are shown in Fig. 2. We confirm this experiment to exhibit outstanding performance of shock tube application in Agriculture and helping for making the pollution free agriculture methodology.

Dr Seema GuptaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : FET, Agra

College, AgraDesignation : Assistant

Professor

Abstract It is well known that nanocrystals with free surface have considerable lattice contraction induced by the large surface/volume ratio. The lattice contraction increases as the size of the nanocrystals decreases. From a mechanical point of view, hydrostatic pressure on the surface induced by intrinsic surface stress results in lattice contraction or lattice strain. Due to this many effects happen, such as pressure ionization, modification in electronic properties, phase change, and several phenomena in applied fields. For this purpose, pressure versus volume relation of condensed matter known as equation of state (EOS) is a vital input. In the present study an equation of state (EOS) is derived for nano-materials and is applied to study the bulk moduli (K) and its pressure derivative of bulk modulus (K`) under different compression in different eight nanomaterials having low to high values of bulk moduli , viz. Rb3C60, CuO (24 nm), ?-Fe, TiO2 (rutile phase) (10 nm), Zr0.1Ti0.9O2, TiO2 (anatase phase) (40 nm), 3C-SiC(30nm), Diamond (NCD). The results have been critically analyzed and are found in good agreement with the available experimental data and are better than others results.

Keywords: Bulk moduli, Volume compression, Nanomaterials

Dr BIPLAB GHOSHImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation :

VIVEKANANDA COLLEGE FOR WOMEN, BARISHA,

KOLKATA-700008Designation : ASSISTANT PROFESSOR in PHYSICS

In this paper, we provide an operational criterion for controlled dense coding with a general class of three-qubit partially entangled states. A general three-qubit pure entangled state can be classified into two in-equivalent classes according to their genuine tripartite entanglement. We claim that if a three-qubit state shows entanglement characteristic similar to $GHZ$-class then such non-trivial tripartite states are useful in {\it controlled dense coding} whereas states belonging to $W$- class are not useful for that. We start with a particular class of non-trivial partially entangled states belonging to $GHZ$-class and show that they are effective in controlled dense coding. Then we cite several other examples of different types of tripartite entangled states to support our conjecture.

Mr Debraj DasImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Ramakrishna

Mission Vivekananda Educational and Research

InstituteDesignation : PhD Scholar

Nonlinear dynamical systems present a plethora of physical phenomena that are truly fascinating, butwhich at the same time appear counterintuitive and intriguing. A very interesting dynamical featureexhibited by nonlinear systems is that of bifurcation, whereby a given dynamics exhibitsqualitatively different flow structure as one or more dynamical parameters are varied. For a modelnonlinear dynamical system, I will show how one may obtain its bifurcation behavior by introducingnoise into the dynamics and then studying the resulting Langevin dynamics in the weak-noise limit. Asuitable quantity to capture the bifurcation behavior in the noisy dynamics is the conditionalprobability to observe a microscopic configuration at one time, conditioned on the observation of agiven configuration at an earlier time. For our model system, this conditional probability isstudied by using two complementary approaches, the Fokker-Planck, and the path-integral approach.The latter has the advantage of yielding exact closed-form expressions for the conditionalprobability. All our predictions are in excellent agreement with direct numerical integration of thedynamical equations of motion.

Dr Shamik GuptaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Ramakrishna

Mission Vivekananda Educational and Research

InstituteDesignation : Associate

Professor

Abstract has been uploaded as a file below.

Dr Sujay PalImage Delegate ID Theme Details


Research


CalcuttaDesignation : UGC-Dr. D.S. Kothari Post-Doctoral Fellow

We present new results of lower ionospheric disturbances due to the extremely severe cyclonic stormFani over northeastern part of the Indian Ocean. Very Low Frequency radio signal received atCalcutta, India and mesospheric temperature and Ozone data from the NASA’s TIMED satellite areused for this purpose. Significant wave-like oscillations and strong amplitude anomalies in daytimeand nighttime VLF signal were observed when the cyclone center was within 700 km from the receiver.Both the mesospheric Ozone and temperature showed maximum anomalies beyond 3? during the cycloneperiod. Maximum Ozone anomaly and maximum VLF anomaly occurred on the same day when cycloneintensity was maximum, while the maximum temperature anomaly occurred on the next day duringlandfall. Mesospheric temperature enhancement around VLF reflection heights indicates changes in thechemical composition and electron-neutral balance in the D-region ionosphere. Simulation of VLFsignal showed that the D-region reflection height decreased by 7.9 km and the D-region electrondensity increased by 20 times compared to pre-cyclone values at the maximum perturbed area along thepropagation path. Wavelet analysis confirmed significant enhancement of atmospheric gravity wavesspectrum with periods 10 min to 2 h around landfall. Further a strong anti-correlation between totalwavelet power in the wave-band of periods 10-30 min and cyclone pressure suggests a possibility ofmonitoring cyclone intensity from mesospheric gravity waves using VLF radio measurements.

Mr ANIRVAN GUPTAImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Smt. Devkiba Mohansinhji Chauhan College

of Commerce and ScienceDesignation : Assistant

Professor

In recent times, few worship spaces are designed to fulfil the expectations of devotees of attainingthe most required peace of mind from everyday customary to-do list. Inside a temple, the peacefulfeeling is to a large extent related to its spatial acoustics, an area often neglected during designand construction phase. In this study, analysis of bell sound from ten heritage temples in India wasperformed to assess the acoustical parameters reverberation time, early decay time and clarity ofsound by using acoustic analysis programs wavanal, vizIR and sigview. Rather than focusing onabsolute values, emphasis has been placed on looking at deviations between reverberation time andearly decay time. Temples with values of ratio between reverberation time and early decay time closeto unity referred to a more diffused space, since decay curves in this case are more linear. Thesevalues also suggest the distribution and dissipation of sound energy within the temples. The valuesof clarity of sound obtained indicates appropriateness of worship spaces for speech and/or music.The acoustical parameters studied herein would allow characterization of the temple spaces and alsogive a brief idea about the subjective impression of acoustic quality of these places.

Dr Bikas C. DasImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Indian Institute of Science Education and Research

ThiruvananthapuramDesignation : Assistant Professor

Stretchable and self-healable electronic components with natural biodegradable property need to bethe focus in the near future among the researcher community to minimize the present environmentalproblems due to electronic waste. However, printed organic electronic components on a flexiblesubstrate is a promising technological step in that direction. Therefore, solution processedthin-film transistors needs to be developed further to minimize power consumption as a requirementconsidering cost-effective and environmentally sustainable ways. Unconventional and new classes ofsolution-processed high capacitive dielectric films with minimal leakage current are emerging as apromising field of research in this direction to minimize operating voltage of TFTs. Organicthin-film transistors (OTFTs) with relatively high carrier mobility and ultra-low operating voltagehave been fabricated by using the solid redox-electrolyte or anodized metals as gate dielectrics inour group. We have demonstrated OTFTs with very high performance parameters like exceptionally largesaturation hole mobility (?_Sat) up to 8.0 cm2V-1s-1, operating voltage below 1.5V, ION/IOFF ratioas high as 107, and sub-threshold swing below 180 mV/dec. The specific capacitance (Ci) of the gatedielectrics has achieved up to ~ 7.0 µF/cm2 using solid redox active polymer electrolyte and 400 -600 nF/cm2 using anodized aluminum (Al) or tantalum (Ta) layer of thickness below 10 nm. These largecapacitive value of gate dielectrics facilitates to produce charge carrier density as high as1015/cm2 in the channel which is a tremendous achievement in terms of future low power applications.Overall, developed OTFTs with the help of high-quality alternate gate dielectric materials arepromising in terms of cost reduction as well as further miniaturization. Reasonably high performanceof these devices will show a route for cost-effective, green and biodegradable technologies,including printed electronics with more complex applications on flexible data storage andneuromorphic devices.

Mr YOGESH AHERImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : SNJB'S Arts,Comm.& Science

College, Chandwad 423101 Dist. Nashik

Designation : Research Student

This contribution reports an ecological benevolent route for the fabrication of copper oxide nanoparticles (CuONPs) using Leucaena leucocephala L. leaves extracts at room temperature. Phytochemical screening of the fresh aqueous leaves extract showed the presence of tannins, saponins, coumarins, flavonoids, cardial glycosides, steroids, phenols, carbohydrates and amino acids. Copper oxide particles such prepared are in Nano scale and their morphology and size are characterized using field emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, transmission electron microscopy, X-ray diffraction, Fourier transform Infra-red spectroscopy, Brunauer-Emmett-Teller, Barrett-Joyner-Halenda and Photoluminescence analysis. Furthermore, CuO-NPs evinced remarkable antimicrobial, antimalarial and antimycobacterial activity against diverse human pathogens

Keywords: Nanotechnology, Leucaena leucocephala L., CuO NPs, Phytochemical screening, Biological activity.

Dr SUDHANGSHU CHAKRABORTYImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : ASANSOL ENGINEERING COLLEGEDesignation : ASSISTANT

PROFESSOR

Factors controlling the electro-kinetic property of TiO2 nanofluid Sudhangshu Chakraborty Department of BS & HU (Physics), Asansol Engineering College, Asansol,Pin-713305,India [email protected] Ph-7384787072 Abstract: TiO2 nanofluid is technologically important. The high stability or better suspension property makes it essential for various research and industrial applications. The electro-kinetic property is directly connected with the stability of the nanofluid. The prime aim of the present work is to focus the important factors that control the electro-kinetic property of TiO2 nanofluid. The sedimentation of nanoparticles may occur over the time due the enhancement of downward body force and this will further cause agglomeration of the nanoparticles in the base fluid. For that reason, the preparation of stable nanofluid is an important issue. The present study deals with the direct effect of Zeta potential, pH-factor and surfactant (Hexasodium salt (NaPO3)6) on electro-kinetic property of TiO2 nanofluid. The electro-kinetic property of TiO2 nanofluid depends strongly on the suspension property of TiO2 nanoparticles in the base fluid. This is the reason the effect of the above mentioned factors such as Zeta potential, pH-factor and surfactant (Hexasodium salt (NaPO3)6) is important in the vicinity of stability of TiO2 nanoparticles.

References: 1. Chakraborty, S,; Materials Today: Proceedings, 2019 , 11, 714–718

Dr Sudipta PalImage Delegate ID Theme Details


Research


KalyaniDesignation : Assistant

Professor

The Equilibrium Molecular Dynamics (EMD) is applied for computing the thermal conductivity and specific heat of aqueous nanofluid containing hBN nano sheet, through Green-Kubo framework. LAMMPS open source software has been used for the simulation. The concentration (weight 0.454%, 0.9085% and 1.36%) and temperature (293-323K) on thermal conductivity and specific heat observed of aqueous hBN nano sheet. Thermal conductivity and specific heat decrease with the increase of weight concentration. Thermal conductivity of nano-fluid is found to be a linear function of weight percent of hBN nano-sheet concentration. Statistical calculation procedure has been implemented to calculate the specific heat of hBN nano sheet with the same weight fractions. The obtained thermal conductivity and specific heat results from the MD simulation of nanofluids exhibit good agreement with earlier data. Higher fluctuation (oscillatory behavior) in HCACF (heat current autocorrelation function) is observed in case of hBN nanofluid in contrast to base fluid water, which essentially results higher thermal conductivity of nanofluids. References: 1. Laya, A. Star.J. L , Ren G., International Nano Letters, 2015, 5, 1-7 2. Navas J.et al The European Physical Journal Applied Physics, 2017, 78,10901,

Mr KALYAN KUMAR BANERJEEImage Delegate ID Theme Details


Research



Scholar

Effect of Cholesterol on the interaction of sodium chloride with phospholipid membrane

Kalyan Kumar Banerjee, Pabitra Maity and Sanat Karmakar* Soft matter and Biophysics Lab, Department of Physics Jadavpur University,KOL-700032 Email: [email protected], [email protected]

Cholesterol is an essential and important component in all eukaryotic cell membrane. The structure and functions of membranes are greatly influenced by cholesterol. Therefore, effect of cholesterol on the ion-membrane interaction have drawn significant attention in biophysical study. We have systematically investigated the interaction of sodium salt with phospholipid membranes in both fluid and gel phases using dynamic light scattering (DLS), zeta potential and isothermal titration calorimetry (ITC). We have prepared vesicles with DMPC and DPPC in order to access both gel and fluid phases. We have obtained large binding constant(Na+ ) in gel phase of DMPC compared to fluid phase. Interestingly, the binding constant in fluid phase of DMPC (9.64 M-1) was found to be greater than fluid phase of DOPC (0.44 M-1), which suggests that chain saturation affects the Na + binding to the membrane. Ternary mixtures composed of DMPC, DOPC and various concentrations of cholesterol and binary DMPC-cholesterol mixture were studied in order to gain insights into the effect of ions on the formation and structure of cholesterol-rich domains, called rafts. None of these systems show any significant change in the heat flow when vesicles are titrated with sodium salt. From DLS and zeta potential analysis we get that for mixture of DMPC, DOPC+cholesterol, DOPC+DOPG+cholesterol with ion(NaCl) zeta potential increases with the increase of ion concentration and it is also true for different concentration of cholesterol and this is possibly supporting increase in Na+ binding with the lipid-cholesterol structure.

Dr Ganesh PatilImage Delegate ID Theme Details


Research


Science College, ChandwadDesignation : Assistant

Professor

Abstract: Nano ZnO thin films were deposited by spray pyrolysis technique (SPT) using zinc oxide hydrate aqueous solutions onto glass substrates at growth temperature 350oC. The films were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The deposition of thin film results in a layer comprising well-shaped hexagonal ZnO nanorods with diameter of 90–120 nm and length of up to 200 nm. Nanorods were successfully deposited using SPT with grain size around 100 nm. The gas sensing performances of these films for various gases were tested. Films showed highest response to H2S (100 ppm) gas at 50oC temperature with highest selectivity. Keywords: ZnO nanorods, SPT, TEM, H2S gas sensor

Ms Arunima ShuklaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SHUATS,

PrayagrajDesignation : MSc (Ag.)

Biotechnology

Limited availability of genetic marker resources in sweet potato (Ipomoea batatas [L.] Lam.) hinders its genetic research. It is necessary to develop more molecular markers for potential use in sweet potato genetic research. In the current study, genetic diversity assessment of 34 sweet potato genotypes was conducted using 20 primer pairs of Simple Sequence Repeat (SSR) markers obtained from literature to determine genetic relationship. Genetic diversity parameters, cluster analysis, and results showed that the SSR markers used had the average PIC value of 0.312668. Among 20 primer pairs 14 were successfully amplified, where 11 primer pairs showed the polymorphism with maximum 2 alleles per loci and 3 primer pairs were found to be monomorphic. The germplasm collection was divided into two major genetic clusters. The primer pair SP4 gave two unique bands with sizes 400bp and 700bp other than the monomorphic bands of 250bp in I. batatas accession no.EC-13969-A. Thus, SP4 primer pair can be used for genotype specific identification and trait analysis. The accessions viz. EC-324082 (CIP, New Delhi), EC-64037 (NBPGR, Regional Station, Amravati), EC-19716 (NBPGR, Regional Station, Amravati) were found to be identical and thus considered to be duplications. The greatest genetic distance was identified between the genotypes sourced from West Bengal and Columbia. These markers could enrich the current resource of molecular markers for the sweet potato community and would be useful for qualitative and quantitative trait mapping, marker-assisted selection and evolution and genetic diversity studies in cultivated sweet potato and related Ipomoea species. Keywords: Cluster analysis, Genetic diversity, Germplasm, Ipomoea batatas, SSR markers.

Ms Jasmine Beryl Lydia SImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Christian

Medical CollegeDesignation : Student

Objective: The Human Immunodeficiency Virus (HIV), a huge pandemic has affected the lives of millions of people globally. In the recent antiretroviral therapy (ART) era, obesity has taken over the wasting syndrome, which is significant among people living with HIV/AIDS (PLHIV). The objective of this study is to find out the prevalence of overweight and abdominal obesity among adults living with HIV and determine the HIV and diet related factors associated with it. Method: Three hundred consecutive HIV patients attending the out-patient clinic at YRG Medical centre were included in the study. A cross-sectional study design was used and participants were recruited after obtaining an informed consent. A validated questionnaire was used to elucidate socio-demography information, HIV related information and dietary information. Those who had a BMI ?25 kg/m2 was considered as overweight and abdominal obesity was considered as a waist circumference >102cm for men and >88cm for women. Multiple regression analysis was performed and a p-value >0.05 was considered significant. Results: The prevalence of overweight and abdominal obesity was 67% (23.4% males; 21.1% females) and 56% (15% males; 22.6% females) respectively. The factors associated with overweight and obesity included the female gender, age ?50 years, and a higher income. Less physical activity, on ART for more than five years, usage of excess oil in the diet, reuse of cooking oil and consumption of food above the recommended dietary allowance. Conclusion: Since HIV related factors cannot be modified, dietary factors should be modified to prevent overweight and abdominal obesity. Counselling on dietary modifications and regular physical activity can help in preventing co-morbidities associated with obesity.

Mr Devendra KashyapImage Delegate ID Theme Details


Research

Category : OthersOrganisation : RNT Medical

CollegeDesignation : MBBS Final

year

WHY TO BRING INNOVATION :

To combat with growing health issues efficiently and provide the best of healthcare services to nation.WHERE TO BRING INNOVATION

Medicine is broad and so the healthcare strata.It demands innovation from in academia to service provision.Academia is root where young minds read and explore medicine while the practical aspects of medicine are dealt hand to hand in service.HOW TO BRING INNOVATION

The most difficult yet very interesting to answer.MEDICOPRENEURS-THE TRANSLATORS.

Mr Rohit DokeImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Samarth

Education Institute's, Samarth College of Pharmacy


Parkinson’s is age accompanying multifactorial neurodegenerative disorder characterized by selective loss of dopaminergic neurons in substantia nigra pars compacta(SNpc). Silymarin is a polyphenolic flavanoid of Silybum marianum belonging to family Asteraceae, used clinically in the management of hepatic disorders. Silymarin has mainly antioxidant, anti-inflammatory, cytoprotective and neuroprotective activities. Although, the neuroprotective effect of oral supplementation of silymarin is well established, its low absorption from the gastrointestinal tract and rapid excretion limit its bioavailability. In addition to this, it also undergoes extensive enterohepatic circulation, thus oral bioavailability of silymarin is generally very low (0.73% to 2%). In the present study we have evaluated anti-Parkinson’s potential of Novel Silymarin formulations over marketed silymarin and silymarin extract in in-vivo experimental model of rotenone induced mice model of Parkinson’s. The study confirms that the novel silymarin formulations therapy shows neuroprotective potential in rotenone induced Parkinson’s in mice. They having the more ability than silymarin extracts and marketed silymarin formulation to reverse or restored the rotenone induced impaired cognitive function (behavior, learning, memory), improves antioxidants status and mitochondrial complex enzymes activity.

All together the findings of present study conclude that Novel silymarin formulations could provide a better therapeutic option over available marketed formulation for the treatment and management of PD.

Dr J. MARTIN SAM GNANARAJImage Delegate ID Theme Details


Research

Category : OthersOrganisation : National College (Autonomous),

TiruchirappalliDesignation : Assistant

Professor of Physics

Research in the discipline of Science and Technology is gaining charm day by day. Fields likeNanotechnology, Artificial Intelligence, Materials Research, Nanobiotechnology, Bioinformatics etc.,are the centre of attraction today. In the global scenario, these fields are gaining popularity inthe past few decades, but these researches are centuries old in our country and we are experts inthese fields and Indians have proved themselves to be the masters of research even before the birthof Christ. Ancient Indian practices prove that there was a strong scientific reason behind what wefollow in our day today life. Historical evidences show that Indians were the Masters of Medicineand Engineering. A 1000 year old Brahadeeshwara Temple at Tanjore, Tamilnadu is the best example forthe architectural beauty of Indians. The contributions of Charaka and Sushrutha are excellentexamples for the contributions of Indians in the field of Medicine. The practice of curing diseaseswith the extract made from umbilical cord of infants gave rise to the field of regenerativemedicine. In the upcoming years, research in the fields of Science, Engineering and Medicine willachieve an enormous growth. The History of Indian science, engineering and medicine will be anexcellent reference providing basic information for every complicated problem.

Mr Dilip K PatelImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Sam

Higginbottom University of Agriculture, Technology and

SciencesDesignation : Research

Scholar

Abstract: Etodolac loaded solid lipid nanoparticles (SLN) were prepared by optimizing processing parameters using central composite design. Optimization was carried out using two factors such amount of Stearic acid, and amount of lecithin and two responses such as particle size, PDI and Entrapment percentage. Further, optimized batch was characterized for entrapment efficiency, surface morphology, in-vitro release and kinetics, FTIR, DSC, and drug retention by tape stripping method. The morphological observation of SLN dispersion was studied by scanning electron microscopy (ZEISS Multi SEM 505, Germany). From the finding, it was found that increase in amount of lecithin lead to decrease in particle size and increase in entrapment efficacy, while by increasing the concentration of stearic acid the result showed increase in particle size as well as entrapment efficacy. Optimized formulation incorporated in aqueous gel of carbopol and ex-vivo and in-vivo study was performed. SLN gel exhibited faster onset yet affecting a prolonged action as evident from a comparative study with normal gel with respect to in-vitro release and pharmacodynamics study. It is further suggested that changing the ratio of solid lipid and lecithin; release, permeation rate and hence pharmacodynamics activity can be modulated.

References: 1. Bharti,G.: Mohd, F.:Khan, S.: Ali, A.:Baboota, S.: Bulletin of faculty of pharmacy, Cairo University. 2015,53,147-159. 2. Tahir, E.Y.: Sibel, I. T.:, Sevgi, T.: Int. J. Pharm. 2018,548, 255-262. 3. Joshi M, Patravale V,. Int J Pharm. 2008;346:124-132.

Dr Subham BanerjeeImage Delegate ID Theme Details


Research

Category : OthersOrganisation : NIPER

GuwahatiDesignation : Assistant

Professor

World Health Organization (WHO) recommends the use of first-line anti-tuberculosis drugs (ATDs) i.e., rifampicin (RIF) and isoniazid (INH) fixed dose combination (FDC) therapies in tuberculosis (TB) disease. Absorption of RIF from a FDC incorporates INH, is significantly compromised due to its reaction with INH, resulting severe loss of RIF under gastric stomach pH condition Such reduction as FDC formulations has been alleged to be one of the chief obstacles in effective TB treatment. This emphasize us for a need to develop suitable cutting edge advanced bioengineered delivery devices which can attenuate this severe problem to mitigate antimicrobial drug resistance (AMR). Therefore, we designed, prototyped and characterized novel bioengineered (pH specific) bilayer (matrix dependent) 3D printlets (printed tablets) for segregated compartmental delivery of RIF into intestine (to avoid stomach gastric pH induced chemical degradation as alone and FDC) and INH into stomach (no degradation observed as alone and FDC in stomach gastric pH conditions) for the desired treatment against TB. 3D printlets were designed with a two compartment i.e., body/housing, cap, and total assembly using 3D printer and can easily be compared with commercial conventional tablet dimensions. The drug release profile was characterized by pH transfer dissolution in vitro and resulted in time dependent release of the both drugs. The findings of this study support the development of programmable-by-design 3D printlets systems for FDC therapies to enable efficient cutting-edge translation delivery systems in modern TB therapy.

References: 1. Banerjee, S.; Roy S.; Bhaumik, K.N.; Kshetrapal, P.; Pillai, J.; Art. Cells Nanomed Biotech. 2018, 46:S1-540-558. 2. Banerjee, S.; Roy S.; Bhaumik, K.N.; Pillai, J.; J Drug Targeting.. 2019, In Press.

Ms DHANA LAKSHMI MImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SSN College

of EngineeringDesignation : Junior

Research Fellow

Around 70% of the earth is composed of water bodies, out of which only 5% of the oceans have beenexplored. Hence, the exploration of the remaining 65% of water bodies would provide muchunimaginable buried heritage, culture, architecture, etc. Hence, the main objective of this work isto implement underwater object image classification system. Our contribution is a submerged debrisdetector through a combination of high-resolution ROV imagery and a ConvNet classifier. Initially,the captured ROV dataset are pre-processed such as image enhancement, image re-sizing, and imagelabeling. The dataset consists of training samples of 8493 (70%), a validation set of 944 (10%) andtesting set of 2360 (20%) images. A three-layer ConvNet is designed and 64 × 64 input grayscaleimages are convolved with 64 3 × 3 convolution filter. A 2 × 2 max-pooling operation is applied tominimize the spatial size of the representation in order to reduce the number of parameters and toincrease the computation speed. The convolution and pooling mechanism is carried out for the nexttwo-layer with a filter size of 32 × 32 and 16 × 16. Finally, the image size (feature map size) isreduced and more complex features are extracted. These contents are flattened into a one-dimensionvector and fed into a 2-layer fully-connected neural network for classification. The output of thenetwork results in a probability distribution over N classes i.e.) N=0, for background and N=1, foran object in a binary detector. A stochastic gradient descent with ADAM optimizer uses the squaredgradients to scale the learning rate. It is inferred that the proposed binary debris detectorachieved an accuracy of 93.7 % whereas the accuracy of existing detector is 88.7%

Dr Pandi KumarImage Delegate ID Theme Details


Research

Category : OthersOrganisation : The American

College, MaduraiDesignation : Assistant

Professor

Energy efficiency is the main concern of the 21st century. The smartphone could be a trendy batteryoperated device and also the experience of the smartphone usage is entirely counting on the batterylife. The state of the Smartphone can be Screen_OFF and Screen_ON. Majority of the time spent by theuser on the phone is in screen off mode however 30% to 40% of the battery power consumption in thisstate through Always_On Apps. These apps send tiny burst to their server for various functions at aspecific interval of time and keep RRC state busy. This paper proposes an energy-efficient algorithmfor high-speed packet data transfer on a Smartphone called PSEO (PS Energy Optimization). Itschedules data communication throughout the screen off state based on the radio signal quality. PSEOregulate Data_ON and Data_OFF period while not affecting the user convenience based on theindependent value of RSRQ. The proposed research saves the energy up to 28.88%, 78.60% and 16.20% onaverage of total network energy, Screen_Off energy, and overall smartphone energy respectively.

Dr Suman SauImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Siksha O

Anusandhan(Deemed to be University)


The Devices in the Internet exchange information and communicate smartly to realize intellectualized recognition, location, tracking, monitoring and management. In recent dates, the economical consumption of these smart IoT devices is over 100 billion dollars. The IoT market growth rate per year increases explosively. The existing literature survey claims IoT still suffers from privacy and security vulnerabilities Conventional security and privacy approaches like security protocols are inappropriate for IoT applications due to its decentralized topology and the resource-constraints of the majority of its devices. Block Chain based application can facilities decentralized security and privacy on IoT application. Conventional Block Chain consumes significant energy, delay, and computational overhead which are not suitable for most resource-constrained IoT devices. In this research exploration we proposed how the blockchain become lightweight and suitable for IoT based smart city applications In our approach, we will propose three main layers, namely smart block, canopy and cloud. Cloud is used to store IoT data which is secure by Partial Homomorphic Encryption. We propose a practical framework to perform partially encrypted and privacy-preserving predictions which combines adversarial training and functional encryption. A city can be divided into several areas where each area will be considered as a block. The blocks are equipped with sensors to collect real-time data for that area. The canopy network consists few smart blocks miners, administration authorities such as local police station, municipalities etc. The cloud is required to share data between smart blocks and others states/central administration etc. This architecture uses different types of block chains depending on where in the network hierarchy a transaction takes place. The literature study, implementation and qualitative estimation of the proposed IoT architecture based on blockchain will be effective under common security and trust threat models. Keywords: Encrypted Machine Learning, Cyber Security, Cryptography, Hardware Implementation

Mr Kaustav SanyalImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Bengal Institute of Science &

TechnologyDesignation : Assistant

Professor

This paper focuses on generating a speech recognition model that will recognize Sanskrit speech incomplete intelligent manner. In an advanced application of speech recognition algorithm I propose toapply Hidden Markov Model on the Sanskrit phonemes. Sanskrit phonetics is a very elaborated andunambiguous phonetic corpus. Success of this model will allow the Artificial Intelligence scientiststo apply the Maaheshwara Sutra of Laghu Siddhanta Kaumudi so that any word or speech generated withthe use of Sanskrit phonemes can be recognized by the system in a complete intelligent manner.

Prof MALLIKARJUN C KallattiImage Delegate ID Theme Details


Research

Category : OthersOrganisation : RURAL

POLYTECHNIC HaunsbhaviDesignation : Lecturer

In recent years, underwater acoustic communications have received much attention as theirapplications have begun to shift from military towards commercial. Digital communications throughUWA channels differ substantially from those in other media, such as radio channels, due to severesignal degradations caused by multipath propagation and high temporal and spatial variability of thechannel conditions. The design of Underwater Acoustic Communication systems has until recentlyrelied on the use of non coherent modulation techniques. However, to achieve high data rates on theseverely band limited UWA channels, bandwidth efficient modulation techniques must be considered,together with array processing for exploitation of spatial multipath diversity. The new generationof Underwater communication systems, employing phase coherent modulation techniques, has a potentialof achieving at least an order of magnitude increase in data throughput. The emerging communicationscenario in which the modern underwater acoustic systems will operate is that of an underwaternetwork consisting of stationary and mobile nodes. Current research focuses on the development ofefficient signal processing algorithms, multiuser communications in the presence of interfere, anddesign of efficient modulation and coding schemes. This paper presents a review of recent resultsand research problems in high speed acoustic communications, focusing on the bandwidth efficientphase coherent methods. Experimental results are included to illustrate the state of the artcoherent detection of digital signals transmitted at 30 and 40 kb/s through a rapidly varying onemile shallow water Channel.

Dr Neeraj TiwariImage Delegate ID Theme Details

YSC 10334 Frontier areas of Research

Category : OthersOrganisation : BBAU Satellite

CampusDesignation : Coordinator

Mobile Phone is a technology which is gradually increased among children and adolescents. Thechildren of 12 to 17 year olds had their own cell phones. Excess usage of MP can be risky; this ismatter of concern at present. We tried to find the risk of symptom ‘Ringing Delusion’ amongChildren (groups: Preadolescent 10-14 years; Teenager 15-17 years; Young Adulthood 18-20 years) inUP State (India). All the Mobile Phone users were subcategories on the basis of life time use of MPi.e., i.e. LU (Low Users>500 hours), NU (Normal Users>500 to 1000to 5000 hours). The data was collected during 2015 to 2018 and analysedusing SPSS version 16.0. The level of significance was considered to be the cellular phone users/subscriber were analysed through regression testing with binary logisticstechniques. Out of 1151 cell phone users randomly contacted in U.P. state. In this study, targetwas to compare ‘self-repelling’ symptoms among low/ normal/ moderate & heavy users on the basisof different factor such as urban-rural, male-female, preadolescence-teenager-young adulthood. Thedistribution of CP users according to gender was approx. 63.7% male users and rest 36.3% femaleusers. In which 17.5% are of preadolescent (10-14 years), 36% are of teenager (15-17 years) and rest46.5% are of young adulthood (18-20 years) group of age. We found that male children users werefrequently reported ‘Ringing Delusion’ in comparison to female. Further, the ringing delusionwas observed among the young adulthood users (18-20 years old) they used their cell phone underNormal category i.e. >500 to

Mr DASARI NAGA VINODImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SRM


Scholar

We present the Region based faster convolution neural networks for accurate and efficient Smart Intrusion Disclosure Entity (SIDE) using Human Intelligence through Internet of Things. We know that the soldiers are enduring their lives throughout the day and night to safeguard the country. In spite of whole affiliation employed by the defense authority, intruders may cross our border and arrive into our ground to bruise the essential assets of the country and kill the legitimate people. The crucial specification in security is the efficiency to automatically disclose intruder in the Line of Control (LoC). To achieve this goal, we propose an algorithm exhibits an image refining and deep learning positioned data to the separation of intruders as a hazard and consequently alert the defense people. The picture is discursive towards elements by utilizing Faster R-CNN innovation. The lineaments are eradicated from the training posture by utilizing a unique model. Classification is done by using Faster R-CNN algorithm. Percentage accuracy of an image is analyzed. This demonstrates that the intended algorithm is robust, accurate and precise. Our technique accomplishes the exactness focused with the Faster R-CNN innovation is a faster during both training and inference.

Dr Sapana KushwahaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Babasaheb

Bhimrao Ambedkar University (BBAU)


Abstract: The association between diabetes associated hypertension and reproductive disorder has long been a matter of debate. It is therefore noteworthy to know whether testicular impairment is the result of diabetic per se, or an adverse effect of antihypertensive treatment, or a combination of both. Among the most used antihypertensive drugs, the beta-blockers have found to be beneficial therapeutic value in treating hypertensive diabetic patients. It has been accounted that antihypertensive regimens in diabetic individuals severely influence the testicular dysfunction. Present study was aimed to compare the effect of classical beta blocker atenolol with third generation beta blocker nebivolol in diabetic rat testes. To elucidate the role of these ?-blocker in diabetic testes, Sprague Dawley rats were randomized into 8 groups, control group, animal receiving nebivolol or atenolol served as atenolol/nebivolol (10 mg/kg) group, diabetic group and diabetic animal receiving atenolol (10 mg/kg) and nebivolol (2.5, 5 and 10 mg/kg). Diabetes was induced by single dose (55mg/kg, i.p.) of streptozotocin (STZ). After the 4 weeks treatment, the animals were sacrificed and blood glucose level, sperm counts, sperm head abnormality, sperm DNA damage, histology, immunohistochemistry of 8-oxo-dG and western blotting of NF-kB, COX-2, caspase-3, p-38 and e-NOS were performed. Results showed that nebivolol but not atenolol significantly decreased the sperm counts, sperm DNA damage and reduced the sperm head abnormality in diabetic rat. Further, nebivolol significantly reduced the number of 8-oxo-dG cells that showed it decreased the oxidative DNA damage. Western blotting results showed that caspase-3, COX-2 and NF-kB expression were significantly down-regulated by nebivolol while atenolol leads to insignificant changes in diabetic testes. In conclusion, we propose that nebivolol may be considered as a potential candidate for treatment in diabetic patients who are prone to testicular damage.

Mr Lalit BiranwarImage Delegate ID Theme Details


Research

Category : OthersOrganisation : RAJA

RAMANNA CENTER FOR ADVANCE TECHNOLOGY

(RRCAT) INDOREDesignation : Scientific

Assistant D

Lalit Biranwar* Ranjan Kumar# *Accelerator Power Supplies Division RRCAT, Indore 452013, India [email protected],[email protected]

Abstract: In the new design the existing conventional vacuum Tube like tetrode or triode will be replaced with a fast disconnect switch where they are used as a series pass element. The prototype switch will be constructed out of four 4KV 20A high-voltage (IXEL40N400) IGBT’s connected in series with the total voltage handling capability up to 4x4=16 KV equipped with static and dynamic balancing system. The main advantage of using this new technology is faster action and virtually no stress for the components of the high voltage power supply.

All high power RF amplifiers using electron tubes have to be equipped with fast acting systems protecting them from arc damage. The classical approach uses mercury containing ignitron connected in parallel with the protecting device, which in case of emergency shorts the high voltage power supply. An alternative way to achieve the same goal is to use the switch connected in series with the protected device.

In many industrial, missile & space application where high voltage and current is required this inexpensive & compact designed HV solid state switch can be used.

Result & conclusion: We have built and fully tested into resistive load the stack of four modules. During the maximum instantaneous voltage & current handling capabilities test all four switches were tripping off by desaturation protection circuits at 7A.Figure (8a & 8b) shows oscilloscope picture of the voltage on the first and second & third and fourth switch module during turn-on/turn-off cycle (V=4kV;I=7A). The voltage balance between the two IGBT’s was unchanged for a time difference in the application of the control voltages to the switch drivers by as much as 200ns. All switches survived 8 hours endurance test during turn on and turn off operation.

Ms Menaka DImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SRM Institute

of science and technologyDesignation : Research

Scholar

Underwater communication remains a challenging technology via communication cables and the cost ofunderwater sensor network (UWSN) deployment is still very high. In UWSN, the position of everysensor node should be determined and the estimation of node location is important. Many localizationalgorithms have been discovered for the terrestrial sensor networks and there are only fewalgorithms are involved in localization schemes of UWSNs. To Communicate in UW, Acousticcommunication is chosen for its long range with respect to temperature, pressure and salinity.Current Underwater positioning algorithms improves the position accuracy by increasing number ofanchor nodes which results in high energy consumption. In order to solve this problem, Localizationusing Mobile anchor node based on region determination is considered to improve the locationaccuracy with low energy consumption. In this method, the nodes deployed in underwater are localizedby reducing the Propagation and dynamic losses which occur during transmission with increase in datarate using low power consumption.

Mr BHARAT RAJ BHUSALImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SIBIN Tech

SolutionsDesignation : DIRECTOR

Challenges of many types exist in the diverse contexts and dimensions of cyber security scenarios. Although some possible solutions have emerged, achieving perfection will remain a dream as attackers are always one up on the abilities of the security systems anywhere in the world. The idea and perception of good cyber security protection remains at the forefront of many organizations’ information and communication technology strategy and investment. However, delving deeper into the details of its implementation reveals that organizations’ human capital cyber security knowledge bases are very low. In particular, the lack of social engineering awareness is a concern in the context of human cyber security risks. This study highlights pitfalls and on going issues that organizations encounter in the process of developing the human knowledge to protect from social engineering attacks. Despite state-of-the-art cyber security preparations and trained personnel, hackers are still successful in their malicious acts of stealing sensitive information that is crucial to organizations. The factors influencing users’ proficiency in threat detection and mitigation have been identified as business environmental, social, political, constitutional, organizational, economical, and personal. Challenges with respect to both traditional and modern tools have been analyzed to suggest the need for profiling at-risk employees (including new hires) and developing training programs at each level of the hierarchy to ensure that the hackers do not succeed.

Dr Ramesh KumarImage Delegate ID Theme Details


Research

Category : OthersOrganisation : The University

of BurdwanDesignation : Kothari PDF

This review focuses on the merits and demerits as well as opportunities of membrane-integrated photobioreactors (MPBRs) for simultaneous microalgae cultivation and waste remediation. MPBR systems can be used for the cultivation, concentration and harvesting of microalgal biomass using nutrients present in wastewater from different sources. Microalgae are the potential source of biomass, biofuels and various types of secondary metabolites. Biofuels (bioethanol and biodiesel) from renewable resources is critical to slow down the global climate change. Microalgae-based biofuels are not only the clean fuels source in transportation sector but also widely accepted due to non-food fuels sources. Membrane-based systems such as microfiltration, ultrafiltration, nanofiltration, reverse-osmosis, forward-osmosis and membrane distillation can be applied during microalgae cultivation and harvesting as well as downstream enrichment of algal-based products [1]. However, success of membrane-based system for microalgae harvesting depends upon the types of membrane, membrane modules and operating conditions. This article also deals with advantages and disadvantages of using various types of membranes, modules, mode of operation and effect of fouling on the upstream and downstream processes during algal biomass production using various types of MPBRs [2]. Additionally, nutrients concentration, especially nitrogen and phosphorus present in the wastewater along with individual parameters such as hydraulic retention time, solids retention time, light intensity, aeration, temperature and pH have been found important factors affecting the microalgae cultivation in MPBRs [3]. However, membrane fouling is still a major challenge for wide application of membrane system during algal biomass separation. Several novel technologies have been used to mitigate the fouling effects like immobilized microalgae technology, air bubbling and use of antifouling membrane. Such MPBRs have the potential of low-cost and eco-friendly separation, purification and concentration enrichment of algal biomass which can bring the high degree of process intensification for scale-up at industrial stage.

Dr Suman GautamImage Delegate ID Theme Details


Research

Category : OthersOrganisation : kgmu,lucknow

Designation : PhD

Implication of Oxidative Stress Biomarkers in Patients with Gynaecological Malignancy Undergoing Therapy Suman Gautam1, Ranjana Singh*1, Seema Mehrotra2, Kislay Awasthi1

1Department of Biochemistry, King George’s Medical University, Lucknow, India. 2Department of Obstetrics Gynaecology, King George’s Medical University, Lucknow,India. Corresponding Author‘s email:[email protected] Abstract Background: Every year in India, 122,844 women are diagnosed with cervical cancer and 67,477 die from this disease[1].The present study was undertaken in patients of carcinoma cervix to evaluate the Implication of chemo radiotherapy on status of oxidative stress biomarker such as protein carbonyl, lipid hydro peroxide and antioxidants defence mechanism of melatonin and total thiol levels. Patients were delivered radiotherapy by external beam radiotherapy (EBRT) followed by brachytherapy. All patients were given chemotherapy in the form of injection cisplatin. Blood samples were collected from patients as well as control before treatment and within 24 hours and six weeks after chemo radiotherapy. Newly diagnosed women with cervical cancer [N=192], 30-65 years of age and age-matched clinically healthy women [N=192] were included in this study. The mean LOOH and PC levels in all three groups of cases were comparatively higher than controls. Further, the mean LOOH and PC levels increased in cases after the chemo-radiotherapy as compared to pre chemo-radiotherapy., P Refernces: 1. ICO Information Centre on HPV and Cancer (Summary Report 2014.08.22)

Ms ARPITA DASImage Delegate ID Theme Details


Research

Category : OthersOrganisation : DEPARTMENT OF ATMOSPHERIC SCIENCE,

CALCUTTA UNIVERSITYDesignation : Ph.D scholar

Total lightning (in-cloud and cloud-to-ground, IC+CG) flash rate from the ground based lightningdetection network can be used for now-casting of severe weather conditions associated with theconvective weather systems and also helps to understand the formation and development of such eventsduring the pre-monsoon seasons. The study aims at revealing consistent temporal and spatialcorrelation between the lightning and rainfall associated with the Nor’wester events. The presentstudy uses total lightning (TL=IC+CG) data from the Earth Network Total Lightning Network, rainfalldata from the India Meteorological Department (IMD) and Global Precipitation Measurement (GPM)satellite associated with the Nor’wester events of 2018 and 2019 over Kolkata. Results show strongcorrelation between lightning count (CG, IC and TL) and total rainfall amount during theNor’wester events. The correlation is greater for CG flashes than IC flashes which shows higherrainfall associated with higher CG flashes (for both ground based and satellite data). Temporalcorrelation of lightning flash rate and rainfall rate shows that rainfall peak occurred 10 min to 30min after the occurrence of total lightning peak indicating a possibility of now-casting of shortduration heavy rainfall events associated with the Nor’wester events. The precipitation calculatedfrom the lightning flash count can also be an alternative method especially in regions withinadequate radar coverage.

Ms Moumita ChandraImage Delegate ID Theme Details


Research

Category : OthersOrganisation : IIT

KHARAGPURDesignation : Senior

Research Fellow

Natural Sunlight Driven Photocatalytic Hydrogen Generation through Water Splitting using CuS/TiO2 Heterostructured Nanocomposites

Moumita Chandra, Debabrata Pradhan*

Materials Science Centre, Indian Institute of Technology, Kharagpur, 721302 West Bengal, India [email protected]. Natural sunlight driven hydrogen (H2) generation through water splitting has attracted attention as a clean and renewable energy generation process that has enormous potential in converting solar-to-chemical energy using suitable photocatalysts. The major bottleneck in the development of semiconductor-based photocatalysts lies in poor light absorption and fast recombination of photogenerated electron?hole pairs. Herein we report the synthesis of CuS/TiO2 heterostructured nanocomposites with varied TiO2 contents via simple hydrothermal and solution-based process. The morphology, crystal structure, and optical properties of the as-synthesized CuS/TiO2 hybrids are evaluated in detail. Controlling the CuS/TiO2 ratio to an optimum value leads to the highest photocatalytic H2 production rate of 1160 ?mol h?1 g?1, which is 10.5 and 9.7 times higher than that of pristine TiO2 nanospindles and CuS nanoflakes under irradiation, respectively. The enhancement in H2 evolution rate is attributed to increased light absorption and efficient charge separation in CuS/TiO2 hybrid. The photoluminescence and photoelectrochemical measurements further confirm the efficient separation of charge carriers in the CuS/TiO2 hybrid. The mechanism and synergistic role of CuS and TiO2 semiconductors for enhanced photoactivity is further delineated.

References.

1. Chandra, M.; Bhunia, K.; Pradhan, D. Controlled Synthesis of CuS/TiO2 Heterostructured Nanocomposites for Enhanced Photocatalytic Hydrogen Generation through Water Splitting. Inorg. Chem. 2018, 57, 4524?4533.

2. Nath, K.; Chandra, M.; Pradhan, D.; Biradha, K. Supramolecular Organic Photocatalyst Containing a Cubanelike Water Cluster and Donor?Acceptor Stacks: Hydrogen Evolution and Dye Degradation under Visible Light. ACS Appl. Mater. Interfaces 2018, 10, 29417?29424.

3. Bhunia, K.; Chandra, M.; Khilari, S.; Pradhan, D. Bimetallic PtAu Alloy Nanoparticles-Integrated g-C3N4 Hybrid as an Efficient Photocatalyst for Water-to-Hydrogen Conversion. ACS Appl. Mater. Interfaces 2019, 11, 478?488.

Ms Megha JethwaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : University of

CalcuttaDesignation : PhD student

Cancer is generally characterized by abnormal multiplication of cells and dysregulated signalingpathways involved in cell growth. Epidermal growth factor receptor (EGFR) is one such factor thatplays a vital role in regulating cell proliferation, and is therefore a potential target foranticancer drug therapy. Drug development involves the identification of novel molecules, and is atime consuming and expensive process. Development of computational tools has enabled in reducing theinitial cost and time required for lead identification. The aim of the present study is to identifynovel molecules against EGFR from ligand-based pharmacophore model which is developed from a set ofdrug database having biological activity in the range from 160 nm to 660 µm. The database wasdivided into training and test sets. The molecules in the training set were selected on the basis oftheir structural diversity and wide range of biological activities. A pharmacophore hypothesis wasgenerated with the training set using hypogen algorithm and the best ranked hypothesis was selectedto validate the test set. The developed pharmacophore model had high correlation, low RMSD, and highcost difference. After validation, the hypothesis was used to identify potential hits by performingvirtual screening of the drug database. The hits were filtered through Lipinski’s rule of five fordrug-likeliness and ADMET profiles were studied. The study provides information about thepharmacophoric features that are important for inhibition of EGFR antagonists, and can be used foridentifying novel inhibitors. Lead identification using this pharmacophore model will aid initiallead optimization.

Mr Arghya ManiImage Delegate ID Theme Details


Research

Category : OthersOrganisation : BCKVDesignation : Ph.D.

Research Scholar

A study was conducted to find out the best salt combinations when NaCl was partially replaced withKCl and CaCl2 while curing mango pieces. Mango pickle contains 15-20% salt, the consumption of whichcause hypertension and high blood pressure. This is due to excess sodium ion (Na+) consumption.D-Optimal Quadratic Mixture Design using Response Surface Methodology was adopted with 3 mixturecomponents to get 16 mixture combinations of salts. 16 runs were formulated depicting diverse saltmixtures and pickle samples were cured using these 16 different brine formulations. After pickling,the final sample were analyzed for water drawing capacity (g/100g salt), hardness of cured sample(N), water activity (aw), sodium and potassium concentration in pickle (in ppm) and organolepticproperties based on hedonic scale. The result shows that water drawing capacity was maximum(102.692) in the 6th run and minimum (58.364) in 2nd run. Hardness of cured sample (in N) wasmaximum (8.470) in11th run and minimum (6.998) in 9th run. Water activity was maximum in 9th run(0.974) and minimum (0.968) in the 2nd run. Na concentration in pickle (ppm) was highest in the 14thrun (408.715) and lowest in 2nd run (68.715). K concentration in final pickle (ppm) was maximum in6th run (472.222) and minimum in 9th run (28.744). Organoleptic properties based on hedonic scalewas evaluated, it was found that run number 14 and 12 have maximum score of 7.429 and 7.393respectively whereas Run-1 and Run-2 showed minimum score of 6.552 and 6.616 respectively. Furthernumerical optimization showed that formulation with 0.5 fractions NaCl and 0.5 fractions KCl ishaving the maximum desirability of 0.658. Another formulation with NaCl 57.1% and KCl with 42.9% ishaving a desirability of 0.64. This formulation can also be adopted for the purpose ofcommercialization.

Dr RAKESH KANT KAMALImage Delegate ID Theme Details


Research

Category : OthersOrganisation : TERI NEW

DELHIDesignation : RESEARCH

ASSOCIATE

Triggered by the oil crisis of the seventies, natural gas has been gaining importance both as energy source and chemical feedstock. Coal bed Methane (CBM) is thus becoming an important energy source next to natural gas. Although there are extensive studies on microbial communities present in some of the coal beds of USA, Canada, Japan and Australia, so far there are only few studies reported from India. ONGCfirstflown CBM in India from a well in Jharia way back in 1997 and established thermogenic methane potential till now, however mi-crobial enhanced methane production of this field and their native microbial community for methanogenesis has not been explored. Therefore, in this study, coal and water samples were collected from a high temperature thermogenic coal bed methane reservoir of India. Furthermore, molecular techniques along with anaerobic cultivation techniques were used to assess the potential for biogenic methane generation of thermogenic coal bed methane reservoir at high temperature. To screen the indigenous bacteria, for the conversion of coal to methane, 10% (v/v) of the formation water samples were inoculated into methanogens specific MPB media bottles and incubated at 45 °C(well’s bottom-hole temperature). The experimental control media bottles contain 0.5 g bituminous coal under similar condition showed no me-thane production at 45 °C after 30 days. The study revealed that bacteria with 0.3 ?m in width and2.2–5.9 ?m in length with curved rod shape were present both in single as well as in pair. Most of the earlier studies have demonstrated that the numeroussyntrophic bacteria present in the methanogenic consortium can initiate the decomposition of coal and produce soluble intermediates that could be utilized by methanogens. Similarly, in the pre-sent work, the developed consortium TERIOJ1 showed the pre-dominance of thermophilic syntrophic bacteria and methanogens species.

Mr Sureshkumar SImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Sri Krishna

College of Engg. and Technology


Wheel Chair with therapy facility: IoT based Smart Monitoring System for the Disabled & the Elderly Prof. S. Suresh Kumar1,Dr.J.Janet2, Dr.J.P.Ananth3 1Department of Computer Science & Engineering, Sri Krishna College of Engineering & Technology, Coimbatore, Tamil Nadu 2,3Professor, Department of Computer Science & Engineering, Sri Krishna College of Engineering & Technology, Coimbatore, Tamil Nadu [email protected] Abstract: Internet of Things describes an intelligent system where the physical objects in the world are connected with sensors via the Internet which enables are new era of automation design revolutionizing the field of Information Technology. With the advent of IoT technology for the disabled has opened a space for the redesign of the systems which makes them to feel even more comfortable and independent. Due to unfortunate situations and due to age factor, people may tend to became paralyzed or disabled. The number has been considerably increasing every year. They can’t be able to have a normal life but to be dependent on another person’s help. This also imposes them to have a therapist who has to take care of them which pushes them into a psychological pressure. The proposed system aims to provide an IoT based smart system for the disabled who functions by using joystick and voice recognition facility. The system can be able to act as a therapist thereby monitoring the health of the patient facilitating the disabled to be independent and happy. Different sensors are integrated into the raspberry pi 2 kit which facilitates the additional features such as obstacle detection, integrated GPSfacility&monitoring of patients using different wireless body sensors. Since it is cost effective, the main aim is to have a nutshell package in a single wheel chair thereby providing assistance to the disabled and the elderly. References: Design and development of voice/joystick operated microcontroller based intelligent motorised wheelchairH.R. Singh, A Mobin,S Kumar,S Chauhan, S S Agarwal, "Design and development of voice/joystick operated microcontroller based intelligent motorised wheelchair", TENCON 99. Proceedings of the IEEE Region 10 Conference, Vol 2, pp. 1573-1576, 1999.

Mr Tadisetti VenkatraoImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Kkr&ksr

institute of technology and sciences


Highly reliable security system with 00 view and ruling the fraud Authors : *Tadisetti venkatrao & *Peeka Ashok Babu

Tadisetti Venkatrao,Assistant Professor, Deprtment of Electronics and Communication,kkr&ksr institute of technology and sciences, vinjanampadu,Guntur (DT), Andhra Pradesh-522017 Peeka Ashok Babu , Assistant Professor, Deprtment of Electronics and Communication,kkr&ksr institute of technology and sciences, vinjanampadu,Guntur (DT), Andhra Pradesh-522017 Mail id: [email protected] [email protected] Abstract: Images are one of the best sources for implementing highly enforceable security. It has been proved that it is difficult to break security when images are used for enforcing the security. One way to implement security is to recognize an individual it may be human, animal or thing and classify them through an image and tracking various actions being taken by the individual by way of observing the traversing and orientation of the images in 0 degree view which covers entire capturing area. Illegal actions being performed which are noticed through image movements and orientation can be made known through actuating mechanisms and highly advanced alert systems to pretend and for controlling the fraud. Fraud taking place in public places like High security regions, ATMS can be controlled using the mechanisms that detect and track the images. Action should be taken based on detected person/animal/thing. Alerting, mechanisms shall be triggered when a set of actions that requires triggering of alerts are noticed through quality images. Alerting Mechanism includes alerting the authorized person or organization, and also pretending the fraud by inserting several alerting conditions. It requires recent technologies like Internet of things, Embedded systems, high resolution PTZ camera for capturing the images with 0 degree coverage and image processing concepts for processing and examine the captured image. References: 1. E. Komagal & B. Yogameena, N.; Foreground segmentation with PTZ camera: a survey, Springer Science+Business Media, LLC, part of Springer Nature 2018,

Dr Avinalappa HottiImage Delegate ID Theme Details


Research


Agricultural Sciences, Dharwad


In chickpea, high temperature (>35 0C during flowering) is an important factor affecting growth,development and seed yield which reveals loss of productivity. Understanding the mechanism of plantresponse to high temperature is a unique approach in breeding for heat tolerance in chickpea. Hence,present investigation was aimed to identify the genotypes for heat-tolerance on the basis of theirduration of flowering and seed yield performance using heat susceptibility index (HSI), heattolerance efficiency (HTE) and per cent reduction in seed yield under normal and late sowncondition. Twenty elite chickpea genotypes including two checks were evaluated in randomizedcomplete block design with two replications for ten quantitative traits under said sowing conditionsover two years (2014-16) at Bidhan Chandra Krishi Viswavidyalaya, West Bengal. Heat stress causedsignificant reduction in overall mean performances for all characters under late sown condition.Genotypes, ICCV 10, JG 14, Annigeri 1 and RSG 888 were showed superior performance, whereas JGG 1,Vikas, RSG 2, Vaibhav and Vijay and BG 256 showed very poor performance for most of the charactersin both sowing conditions and over the years. Among genotypes, Annigeri 1, ICCV 10, JG 14, Pusa 372,and JAKI 9218 were identified as thermo-insensitive and exhibited least HSI value and per centreduction in seed yield with highest HTE, whereas JGG 1 and Vijay showed HSI value more than one andmaximum per cent reduction in seed yield with lowest HTE under late sown condition, as a result,these genotypes are most thermo-sensitive. Further, days to 50 per cent flowering had found negativeassociation with maximum temperature, thus indicated that the genotypes were exposed to temperaturesup to 37.00 0C under late sown condition. The identified heat tolerant genotypes could be used infuture breeding program of chickpea.

Mr Amit GhoshImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Dream Institute of Technology


The design of a circular patch antenna with parasitic elements to achieve the desired dual band is presented. Microstrip patch antenna has been used enormously due to its advantage of low cost, lighter weight and ease of fabrication. The challenge persists in its narrow bandwidth.Now, if we make use of this narrow bandwidth and high selectivity as specific passband for particular 4G and 5G frequency range then we make use of this antenna application specific. With the advent of new upcoming 5G technology the 4G technology needs to be replaced. The transition of technology is not easy once it’s commercialised. So there must be a technology that shall satisfy both.The antenna is designed deliberately to bridge the present 4G technology with the future 5G technology incorporated in same design. The construction is made such that the circular patch has centre frequency of 2.4 GHz covering 4G frequency band whereas the parasitic patch introduced gives us another pass band of 3.5 to 4 GHz suitable for using 5G. The normal single circular patch antenna resonates with dominant mode TM11 and other higher order mode TM21 at frequency 2.4 GHz and 4.8GHz respectively. Whereas the parasitically loaded circular patch antenna gives primary resonance (with dominant mode) at 2.6 GHz and other resonance from 3.5 GHz to 4 GHz range. Calculation is done based on cavity model formulation, a design procedure is outlined which leads to practical designs of a circular microstrip antennas for dominant TM110 mode. The SMA connector fed antenna is designed and simulated by FEM(Finite Element Method) solving software and response are observed. . This antenna shall be useful for CDMA ,4G, and proposed 5G communication in addition with WiFi system.

Dr Dinesh SharmaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Vidya College of Engineering, Meerut (INDIA)

Designation : Professor

Sustainable Lifestyle for mitigating climate change by single use plastics

Dinesh Kumar Sharma*1, Meenakshi Sharma2 1Vidya College of Engineering, Meerut (India) 2Dewan V.S. Institute of Education, Meerut (India), *Contact Author Email: [email protected]

Abstract: Sustainable development is the important for a healthy, prosperous and livable planet. Climate change is one of the most emerging concerns for everybody. Jambeck et al. elaborates that recycling of only 9% plastic of total produced has been done. 12 % has been destroyed by burning and remaining 79% plastic waste has been gradually accumulated in landfills and dumps, oceans and rivers or atmosphere. Every year, a huge amount of plastic waste about 8 million tonnes finally drains in oceans (through rivers). Plastic waste persists for hundreds of years in environment if not tackled properly. And with the current pace of single use plastics, it would be unfortunate for our oceans to hold more plastic than fish by 2050.

In view of all climatic threats by overwhelming use of single-use plastics, immediate remedial actions are needed at not only global level but at national, regional and local level too. Besides the multiple climatic and environmental threats, plastic based products are found to be more convenient, durable and cost effective in our daily applications. Therefore, sensible and sustainable solutions such as awareness in public, government policy and scientific advancement are three key factors which can be adopted for a green and sustainable society. Sustainable lifestyle (with Reuse, Recycle and Reduce) is essential to handle the risks of plastics. Cost-effective production of bio-degradable plastic is another effective alternative to single use plastic to prevent ecological hazards. References: [1] Jambeck, J.R., Andrady, A., Geyer, R., Narayan, R., Perryman, M., Siegler, T., Wilcox, C., Lavender Law, K. , (2015). Plastic waste inputs from land into the ocean, Science, 347, p. 768-771.

Ms Dr. sameera akhtarImage Delegate ID Theme Details


Research

Category : OthersOrganisation : govt. medical

college dodaDesignation : Demonstrator

TITLE: UTILITY OF CBNAAT IN DIAGNOSIS OF PULMONARY AND EXTRA PULMONARY TUBERCULOSIS IN A PREDOMINANTLY RURAL MOUNTANOUS REGION OF JAMMU AND KASHMIR ( GMC DODA) INDIA AUTHORS:Dr.Sameera Akhtar*, Dr. Sufhia Akhtar AFFLIATION: 1.Dr. Sameera Akhtar, Demonstrator, Department of Microbiology GMC DODA 2.Dr. Sufhia Akhtar, HOD , Department of Microbiology GMC DODA Author E-Mail:[email protected] (9018687313) Abstract: BACKGROUND: Tuberculosis is the ninth leading cause of death worldwide. India contributes to about one fifth of global TB burden. It is very important to diagnose early and treat Tuberculosis . We compared the cartridge-based nucleic acid amplification test (CBNAAT) results for diagnosis of pulmonary and extra-pulmonary tuberculosis with the conventional methods like sputum smear . MATERIAL AND METHODS: We conducted a retrospective study in department of Microbiology to analyze the utility and yield of CBNAAT from Jan 2017 to December 2017. We included all patients who were subjected to AFB stain and CBNAAT in the study period. Results: Out of 300 clinically suspected cases of pulmonary and extra pulmonary Tuberculosis, 22O cases were Pulmonary samples and 70 cases were extra pulmonary samples. Out of 220 pulmonary samples, CBNAAT was positive in 180(82%) samples and negative in 40(18%) samples, and out of 70 extra-pulmonary samples ,CBNAAT was positive in 60(86%) samples and negative in10(14%) samples . In our study on pulmonary samples by AFB stain, Sensitivity was found to be 51 %, specificity was 92.5%,positive predictive value 96.84 %, Negative predictive value 29.6 In our study on extra-pulmonary samples by AFB stain, Sensitivity was found to be 58.33 %, specificity was 80%, positive predictive value 95 % and Negative predictive value was 24.24% respectively. CONCLUSION: To conclude, CBNAAT is one of the rapid diagnostic tests available in the country and it should be routinely used under the public and private health sectors efficiently to detect a tuberculosis case.

Dr Nazia TabassumImage Delegate ID Theme Details


Research

Category : OthersOrganisation : govt.medical

college dodaDesignation : Registrar deptt.

of pathology

AIMS: 1. To study role of bronchoalveolar lavage, transbronchial needle aspiration and bronchial biopsy in diagnosing lung malignancies. 2. To find comparative diagnostic evaluation of BAL and TBNA with bronchial biopsy in lung malignancies. 3. To find sensitivity and specificity of these techniques.

METHODS: 1. The study was conducted at SKIMS, India in the Department of Pathology. It was a prospective study over a period of 1 ½ years from June 2015 to December 2016. 2. In the prospective study of 1 1/2 years all histopathologic slides of bronchial biopsies and cytology slides of TBNA and BAL received in the department were followed. Bronchial biopsies, TBNA and BAL done for diseases other than cancer were excluded from the study. 3. A total of 47 cases were collected for IHC RESULTS : 1. Out of a total 117 clinically suspected cases of lung cancer, tumor was found in 103 cases (103/117) by biopsy, 51 cases by BAL (51/117) and 64 cases by TBNA (64/117). The total number of false positive cases and false negative cases by BAL were 6 and 58. Sensitivity of BAL was found to be 43.69% and specificity 57.14%.The total number of false positive cases and false negative cases by TBNA were 7 and 46.Sensitivity and specificity of TBNA was found to be 55.34% and 50.0 % 2.The most common type of lung cancer on biopsy and after IHC confirmation was squamous cell carcinoma 55.33% (57 cases).The second most common type of lung cancer was small cell carcinoma 20.38%(21 cases).To conclude diagnosis was highest with bronchoscopic biopsy with sensitivity of 88.034%.Thus we can say that combining three modalities of investigations like Bronchoscopy, BAL and TBNA ,we can diagnose cases of carcinoma lung much effectively than using individual modalities there by increasing sensitivity and specificity.

Mr Jugraj SinghImage Delegate ID Theme Details


Research

Category : OthersOrganisation : RGIPT

Designation : BTech Student

Thermochronometer age provide time since our temperature thermochronometers have cooled down till present. In normal scenarios, they cool down as the formation move towards the surface and gets eroded by natural agents or exhumation & gets warm when the formation subsidies or advection. Low temperature thermochronometers have low effective closure temperature which is in junction to oil and gas window, AFT have closure temperature ~120° C while range of oil window lies between 50° - 150°C. Numerical model for predicting the Apatite Fission Track (AFT) age using low temperature thermochronology has been developed using Python under various condition of exhumation and subsidence of a basin in 1-D. The model requires certain material parameters & characteristics such as subsidence and exhumation velocity, conductivity, thermal diffusivity, thermal gradient, depth, density of rock, transition time, specific heat, etc. Thermal history of the rock is modelled whose result predict the thermochronometer age. Other parameters of thermochronometers are also incorporated as per Laslett et al. (1987) and Crawley et al. (1991) if we want to shift from AFT parameters to Durango parameters. Model provides with the AFT age of mineral along with the fission track length distribution statistics in the mineral at present time and depth history of the rock. The model has certain limitations as no radiogenic heat production is considered in the simulation, the mineral’s current depth is zero i.e. it lies on the surface, its composition has been same through out the simulation run time and only 1D movement is considered. Degree of maturation of organic matter i.e. kerogen in the rock depends on the maximum temperature it has achieved in its thermal history and the amount of time it has spend in that temperature range. Low temperature thermochronology helps to relate the age of cooling to the oil and gas window and help to identify whether the kerogen has been burnt, overcooked or preserved in the rock.

Dr Saptarshi DhibarImage Delegate ID Theme Details


Research


Association for the Cultivation of Scinece

Designation : CSIR Research Associate (Direct)

Ternary Nanocomposites based on Graphene Nanoplatelets, Single Walled Carbon Nanotubes and Polypyrrole for High Performance and Flexible Solid-State Symmetric Supercapacitor Saptarshi Dhibar and Sudip Malik* School of Applied and Interdisciplinary Sciences (formerly Polymer Science Unit), Indian Association for the Cultivation of Science, 2A and 2B Raja S.C. Mullick Road, Jadavpur, Kolkata – 700032, India Sudip Malik ([email protected]); Saptarshi Dhibar ([email protected])

Abstract: With the rapid depletion of fossil fuels and rising energy consumption, the development of renewable as well as sustainable energy source has become one of the foremost challenges in energy storage. Herein, a low-cost and easy preparation procedure has been employed for the fabrication of nanocomposites based on graphene nanoplatelets (GP), single-walled carbon nanotubes (SWNTs) and polypyrrole (PPy) [GNP/SWCNTs/PPy] for the superior supercapacitor electrode materials by taking advantage of electrochemical double layer capacitance of carbonaceous moieties and pseduocapacitance of conducting polymer. Spectroscopic techniques have suggested the interactions of both GNP and SWCNTs with PPy. GNPs are homogeneously covered by PPy and the covered GNPs are wrapped by PPy coated SWCNTs to have a unique morphology, observed from morphological analysis. Highest specific capacitance of 1224 F/g at current density 0.5 A/g, better energy and power density have been achieved for the nanocomposite. Further, GNP/SWCNTs/PPy based all-solid state flexible supercapacitor device has been fabricated and it has showed the specific capacitance of 324 F/g at current density 0.5 A/g, energy density of 28.8 Wh/kg and power density of 1975.22 W/kg. Apart from these electrochemical characteristics, these nanocomposites have exhibited nonlinear current–voltage characteristic, indicating the semiconducting behavior. Considering the excellent electrochemical properties, these nanocomposites should be used for the superior electrode materials for the fabrication of coin-type supercapacitor.

References: Dhibar, S.; Roy, A.; Malik, S. Eupoean Polym. J. 2019, 120, 109203.

Mr MOHAMMAD SHAHNAWAZ KHANImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : ALIGARH

MUSLIM UNIVERSITYDesignation : RESEARCH

SCHOLAR

Water pollution is one of the most severe problems in the world, which puts the survival anddevelopment of human society at risk. Therefore, developing efficient and cost-effectivetechnologies for the removal of water pollutants has become a hot topic. Keep this in our mind atetrazole based metal organic framework [Cu(Metet)]n (MOF-1) (MetetH = 5-methyl-1H-tetrazole) hasbeen prepared under solvothermal condition using sodium azide and nitrile in presence ofCuCl2•2H2O. The crystalline product thus obtained was characterized by spectral (FTIR,UV–visible and fluorescence) and single crystal X-ray difraction analysis. X-ray data conirm thetetrahedral geometry around the Cu(II) ion where all the four coordination sites are provided byfour N of the four diferent ligand (Metet). MOF-1 has trigonal crystal system with R-3 m spacegroup. Topological analysis of MOF-1 shows 4,4-c binodal net with uncommon ptr topology andstoichiometry, (4-c)(4-c). The detailed structural analysis reveals the porous nature of the MOFwith channel of dimensions, Rf = 0.6 Å and Ri = 2 Å. Further, the present MOF shows excellentadsorption properties towards organic dye, methelene blue (MB) and thus can be employed as a goodadsorbent for organic pollutants to remove MB from waste water. The possible rationale behind thedye adsorption is the porous nature of the MOF-1.

Dr ANJOY MAJHIImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Presidency


Professor

ABSTRACT: Quinoline, coumarin and triazole containing compounds shows enormous biological activities such as antiviral, antibacterial, antifungal, anti-inflammatory, anticancer activities etc. Fluorescent probes are powerful tools for biosensing and bioimaging because of their high sensitivity, specificity, high fluorescence intensity, excellent solubility, biocompatibility and simple preparation. They can provide direct visualization and dynamic information concerning the localization and quantity of biomolecules of interest. Design and synthesis of some fluorescent probe based on CuAAC reaction and the investigation of the fluorescent property and interactions of the synthesized compounds with both the serum albumins BSA/HSA by different photophysical studies for development of biomedicines in the drug design or drug delivery process at very preliminary stage of the modern research. Protein ligand binding study is very important in drug design and developing system. In present work, novel triazole based quinoline and coumarin compounds were designed and synthesized using CuAAC reaction (Click reaction).1,2 The binding interaction of the synthesized compounds with serum albumins has been explored using different photophysical studies. To determine the feasible binding sites and change in the microenvironment of the binding sites of the tryptophan (Trp)/tyrosine (Tyr) of the serum albumins exploiting Trp/Tyr emission in proteins, steady state and time-resolved fluorescence at room temperature (298 K) and low-temperature phosphorescence studies at 77 K have been explored in the present work. Molecular docking studies further predict the experimental findings of the protein-quinoline and coumarin complexes. This above study provides information about the role of novel quinoline, coumarin and triazole containing compound acting as drug molecule at a very preliminary stage of research. References: 1. Paul, S.; Roy, P.; Sardar, P. S.; Majhi, A. ACS Omega, 2019, 4, 7213-7230. 2. Paul, S.; Ghanti, R.; Sardar, P.S.; Majhi, A. Chem. Heterocycl. Compd. 2019, 55 (7), 607-611.

Dr CHAITALI BAGADEImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Shivaji

University, KolhapurDesignation : Assistant

Professor

In present work we report, a facile chemical route for the deposition of Cd1-xZnxSe thin films byusing a simple, self organized arrested precipitation technique (APT). Effect of Zn content onoptical, structural, morphological, compositional and photoelectrochemical properties in Cd1-xZnxSethin films were investigated. The optical properties and band gap profile of Cd1-xZnxSe thin filmswere varied with respect to Zn content. Estimated direct optical band gap was found to be in therange of 1.77 to 1.98 eV. X-ray diffraction (XRD) studies reveal that films were nanocrystalline innature with a pure cubic crystal structure and calculated crystallite size lies in the range 36.5 to66.3 nm. Scanning electron microscopy (SEM) demonstrates that surface morphology can be improvedwith incorporation of Zn into CdSe lattice. Compositional analysis of all samples was carried outby using energy dispersive X-ray spectroscopy (EDS) and X-ray photoelectron spectroscopy (XPS), itconfirms stoichiometric deposition of Cd1-xZnxSe thin films. J-V characteristics of all samples werestudied in sulphide/polysulphide redox electrolyte. High efficiency 0.68% was observed due to lowercrystallite size and higher surface area. These results show that by varying Zn content inCd1-xZnxSe thin films photoelectrochemical performance can be enhanced.

Dr Sarvesh Kumar PandeyImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IISc

Bangalore Designation : Postdoctoral

Associate

Attempts to establish degrees of aromaticity in molecules are legion. In the present study, we begin with a fictitious fragment arising from only those atoms contributing to the aromatic ring and having a force field projected from the original system. For example, in benzene, we adopt a fictitious C6 fragment with a force field projected from the full benzene force field. When one bond or angle is stretched and kept fixed, followed by a partial optimization for all other internal coordinates, structures change from their respective equilibria. These changes are the responses of all other internal coordinates for constraining the bond or angle by unit displacements and relaxing the forces on all other internal coordinates. The “interaction coordinate”[1] derived from the redundant internal coordinate compliance constants measures how a bond (its electron density) responds for constrained optimization when another bond or angle is stretched by a specified unit (its electron density is perturbed by a finite amount). The sum of interaction coordinates (responses) of all bonded neighbors for all internal coordinates of the fictitious fragment is a measure of the strength of the ? and ? electron interactions leading to aromatic stability. This sum, based on interaction coordinates, appears to be successful as an aromaticity index for a range of chemical systems. Since the concept of 'aromaticity index based on interaction coordinates (AIBIC)'[2] involves analyzing a fragment rather than the whole molecule, this idea is more general and is likely to lead to new insights.

References: [1] Jones, L. H. Inorganic Vibrational Spectroscopy; Marcel-Dekker: New York, 1971. [2] S. K. Pandey, D. Manogaran, S. Manogaran, and H. F. Schaefer III, Quantification of Aromaticity Based on Interaction Coordinates: A New Proposal J. Phys. Chem. A 120, (2016), 2894-2901.

Dr Arun PalImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IACS, Kolkata

Designation : National Postdoctoral Fellow

Singlet fission (SF) produces two coupled triplet excitons from a high energy singlet excitation. The mechanism of SF in a variety of phenyl (–Ph) substituted pentacene is systematically studiedthrough both ab initio and density functional theory calculations. Two classes of substitution topentacene are considered namely, symmetric configuration with four Ph groups (TPP) and an asymmetricconfiguration with two Ph groups (DPP). The position of the singlet and triplet states aredetermined by calibrating the active space through state average complete active spaceself-consistent field (SA-CASSCF) calculations. The SF rates are computed based on restricted activespace with single and double spin flip wave functions (RAS-SF and RAS-2SF), which are analyzed basedon different intermolecular ?-stacking patterns of TPP and DPP. The contribution of charge transfer(CT) state near the multiexciton (ME) state plays a significant role for SF efficiency. The role ofexcimer formation is supportive for ME generation [J. Am. Chem. Soc. 2016, 138, 617] and hence it iscritically studied. The ME generation in TPP is a slower process and occurs through anexcimer-mediated path with a large coupling between the first singlet excited state and ME state. Onthe other hand, DPP exhibits a relatively faster SF rate through the formation of a ME state vialow-lying CT state, especially the slip-stacked dimers. The present computation elegantlydemonstrates the crucial role of functional group substitution in the structure of SF activemolecules in determining the efficiency of fission dynamics.

Mr MANISH DIXITImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Indian Institute of technology

(Bananas Hindu University)Designation : Ph. D. student

The gels have attracted immense current interest because of their potential application in diverse areas.1 Especially, the chiral coordination based gels may exhibit the unique properties such as morphology, optical, color, rheology, magnetism, adsorption, emission, catalytic activity and redox behavior due to the presence of chirality and metal ion.2,3 Considering the points, three chiral structural (positional) isomers have been synthesized by varying the –NO2 group position by molecular engineering on l-tartaric acid. In the presence of LiOH, isomer 1 forms a red-colored gel which exhibits interesting morphology, anomalous optical and rheological properties (Figure). Notably, isomer 2 and 3 produce different results under similar conditions. The anomalous color displayed by gel as well as distinct gelation behavior of the structural isomer 2 and 3 attracted our attention to exploring gel as a good candidate for charge transfer studies (Figure D & E). The position of the –NO2 not only tuned gelation but, also, optical properties (Figure D). Further, the role of alkali metal ion behind charge transfer and aggregation was attested by the detailed titration experiments with crown ether (Figure E).

References: 1. Piepenbrock, M. M.; Lloyd, G. O.; Clarke, N.; Steed, J. W. Chem. Rev. 2010, 110, 1960-2004. 2. Dubey, M.; Kumar, A.; Pandey, D. S. Chem. Commun. 2014, 50, 1675-1677. 3. Dubey, M.; Kumar, A.; Gupta, R. K.; Pandey, D. S. Chem. Commun. 2014, 50, 8144-8147.

Mr D N MADHU SUDANImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : University of

MysoreDesignation : Student

Catalytic oxidation of toluene by using transition metal oxides (polyoxoniobates). These oxides either are used in the pure form or are deposited on various carriers. The most characteristic product of toluene oxidation is benzaldehyde. It was noted that, when the reaction was performed on usual oxide “mild” oxidation catalysts, it terminated at the stage of benzaldehyde formation, whereas benzoic acid was present in oxidation products in insignificant amounts. It follows that niobium-containing catalytic systems were most active and selective in the oxidation of toluene to benzaldehyde and benzoic acid, and catalysts based on niobium oxides were most simple to prepare. For selective oxidation reactions, there is a tremendous challenge to prevent over oxidation of the products, which are often more sensitive to be oxidized than the reactants. The direct oxidation of toluene by oxygen to produce benzaldehyde is such a reaction. Benzaldehyde is a chief raw material in the synthesis of other organic compounds, ranging from pharmaceuticals to plastic additives. It is also an important intermediate for the processing of perfume and flavouring compounds and in the preparation of certain aniline dyes. Currently, benzaldehyde is mainly produced via the toluene chlorination/hydrolysis process, which generates large amounts of toxic acidic waste, leading to equipment corrosion and costly separation processes. The study on the oxidation of toluene to benzaldehyde by oxygen via heterogeneous catalysis has continued for more than twenty years. In recent years, the selective oxidation of toluene to benzaldehydes under mild conditions in the liquid state with hydrogen peroxide, t-butyl hydroperoxide or molecular oxygen as oxidant using transition metal oxides as catalysts has attracted research interest. However, progress has been limited and new exploration has been continuously desired.

Mr MOHD DANISH ANSARIImage Delegate ID Theme Details


Research


OF ALLAHABADDesignation : RESEARCH

ASSISTANT

A synergistic catalysts system ZnO NPs and Malic acid was used for the highly efficient andeco-friendly synthesis of oxazines and thiazines derivatives. Aldehyde, urea and alkyne derivativesare used as reactants under ultrasonication, which not only allows clean and rapid alteration butalso simplifies experimental setup. High yields, environmentally benigness, simple work-up andshorter reaction times are some remarkable advantages of this strategy.

Dr Vikram SinghImage Delegate ID Theme Details


Research


Institute of Technology, Kanpur, India

Designation : Institute Postdoctoral Fellow

Carbon quantum dots (CQDs) are potential candidates for numerous modern nanotechnologies and biomedical research. Owing to their simple one-pot synthesis, unique excitation-dependent emission, excellent photochemical stability, and high biocompatibility, these water-miscible CQDs have shown great potential as an alternative source to conventional organic fluorescent dyes and inorganic semiconductor QDs.1-3 A simple, one-pot eco-friendly synthesis of blue (B) and green (G) emitting carbon quantum dots (CQDs) from beetroot aqueous extract was developed. These biocompatible, photostable and non-toxic CQDs exhibited bright fluorescence in aqueous medium and successfully used for non-invasive in vivo fluorescence bio-imaging in Caenorhabditis elegans and mice models (Figure 1)4. Further, we have synthesized N-doped CQDs from watermelon aqueous extract and obtained convincing evidence for tumor targeting in mice (manuscript under preparation). The details of synthesis, photophysical properties, and applications of these CQDs will be discussed during the poster presentation.

Dr Raman Kumar SinghImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Jai Prakash

University, Chapra, BiharDesignation : Assistant

Professor

The one dimensional (1D) carbon nanowire made of a long linear carbon chains inserted inside a multiwalled carbon nanotube (MWCNT) are of great interest for the advancement of nanotechnology, material science and the basic research due to its optical and electronic properties. Recently, D. Nishide et al. synthesized single (double)-wall carbon nanotubes encapsulating C10H2 polyyne molecules, and observed that a high-temperature fusion reaction occurs to form long linear carbon chains.[1,2] However, the reaction pathways for such fusion reactions are still unknown experimentally/theoretically, as far as we know. To address this problem, we have considered the minimal polyyne (C4H2) nano-fusion reactions as a first step to study using density functional theory. The results show that C4H2 fusion reaction follows open-shell singlet reaction pathways in gas phase.[3] References: 1. Nishide, D.; Dohi, H.; Wakabayashi, T.; Nishibori, E.; Aoyagi, S.; Ishida, M.; Kikuchi, S.; Kitaura, R.; Sugai, T.; Sakata, M.; Shinohara, H. Chem. Phys. Lett. 2006, 428, 356-360. 2. Zhao, C.; Kitaura, R.; Hara, H.; Irle, S.; Shinohara, H. J. Phy. Chem. C 2011, 115, 13166– 13170. 3. Singh, R. K. (Manuscript under preparation)

Dr Ananta Kumar GhoshImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Burdwan Raj college under Burdwan Univer

Designation : Associate professor

Supramolecular Interactions and Structural Diversity Ananta Kumar Ghosh* Burdwan Raj College, Purbo-Bardhaman, Pin-713104, W.B e.mail: [email protected]

Supramolecular chemistry is the chemistry beyond the molecule. It focuses on the assembled of molecular subunits. The traditional interactions focus on the covalent bond that may vary from weak to strong and are responsible for the spatial orientations. While the supramolecular interactions are the weak interactions where interactions energy is very low. It includes the hydrogen bond, hydrophobic interactions, ?-?- interactions, C-H….? interactions, and van der Waals forces etc.... It deals with the molecular self-assembly, recognition, host-guest chemistry, crystal engineering, molecular architectures etc…. and more over this weak interactions are responsible for many biological processes. Eventually, chemists were able to synthesize many compounds. The breakthrough was with the synthesis of the crown ethers. Later the development of selective "host-guest" complexes. A major application of supramolecular interactions is in the solid state chemistry directed by non-covalent bonding. This interactions play crucial role in the application of magnetic materials, light responsiveness, synthetic ion channels, molecular sensors, but also in the design of metallo-organic frameworks.

References: 1. Lehn J.-M. Supramolecular Chemistry–Concepts and Perspectives; VCH: Weinheim, Germany, 1995. 2. Fujita, M. Molecular Self Assembly Organic versus Inorganic Approaches; Structure and Bonding, Vol. 96; Springer–Verlag: Berlin Heidelberg, Germany, 2000. 3. J. L. Atwood, J. W. Steed, Supramolecular Chemistry; VCH: Verlag Gmbh, Weinheim, Germany, 2000. 4. G. R. Desiraju, In The Crystals as a Supramolecular Entity; J. M. Lehn, Eds.; Vol 2, John Wiley & Sons, Chester, U.K. 1996; e) Desiraju, G. R. Angew. Chem., Int. Ed. Engl. 1995, 34, 2311. 5. Ghosh, A. K ; Hazra, A; Mondalb, A; Banerjee, P. Inorganica Chimica Acta 2019, 488, 86-119

Mr SUDALAIMANI SImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : CSIR-CECRI

Designation : Project Assistant

Liquid-liquid interfaces play an important role in some physical, chemical,and biochemicalprocesses. The electrochemical properties of interfaces between two immiscible electrolyte solution(ITIES) have been intensely studied for more than 30 years. Spoilage food contain some chemicalcompounds. Using ITIES to detect some of them.

Dr HIMANSHUBHAI DILIPBHAI PATELImage Delegate ID Theme Details


Research



Professor (Chemistry)

A series of some heterocycles containing thieno[2,3-d]pyrimidine moiety were synthesized as an antimicrobial agents from the key compound ethyl-2-amino-4,5-dimethyl thiophene-3-carboxylate. The structures of the synthesized compounds were confirmed by IR and elemental analysis. In vitro antimicrobial activities of the targeted compounds was tested against some Gram-positive, Gram-negative bacteria and fungal strains. Some of the tested compounds showed promising activity. Keywords: Benzothiazole, Chalcone, Thieno[2,3-d]pyrimidine, Biological activities

Mr Kaushik NaskarImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Jadavpur


Scholar

Porous coordination polymers (PCPs), owing to the high surface area and variable pore architecture,are valuable material in sorption and separation of gases, catalysis, fluorosensors, and drugdelivery. The porous materials are also efficient storage and exchange systems of small moleculesand ions such as I2, I3?. Iodine, an important trace element to human health, marine environments,and in organic synthesis as a catalyst, has recently been the focus of public issues because of thegrowth of the nuclear industry. It is important to design selective metal-organic framework (MOF)comprising an appropriate active site that may absorb iodine effectively. It is demonstrated thatpolar cavity with electron-donating groups, for example, ?OH and ?NH2, normally improve iodinesorption efficiency, which leads to increased electrical conductivity. The metal?iodide (M-I)coordination bond(s) in the PCPs may enhance I2 capturing capacity via M?I•••I2 binding, thusincreasing the sorption amount for iodine. We have successfully decorated the porous channel ofPorous Polycatenated Coordination Polymer (PPCP) as a Cd?I bond in it. The activated Coordinationpolymer (1?), adsorbs N2, and the adsorption? desorption analysis displayed the increase in porosityto mesoporous range (?14.7 nm) with very high specific Brunauer? Emmett?Teller surface area (846 m2g?1), which may be due to the rise in interparticle void space. Iodine sorption studies ofmesoporous architecture of 1? show high removal efficiency (98.9%), which is revealed from thereversible iodine uptake kinetics study. Interestingly, the iodine-loaded polymer (I2@1?) shows ?1.5times enhancement in electrical conductivity compared to 1? only. The optical band gap obtained fromdensity functional theory (DFT) calculation.

Dr NANDA DULAL PAULImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Indian Institute of Engineering

Science and Technology, Shibpur


With the rapidly growing world population and improved living standards there is a continuous need of various new chemicals and energy for smooth running of our day-to-day activities while the natural resources like fossil fuels, scarce elements are depleting rapidly. To ensure a sustainable society the essential commodities need to be obtained from the available renewable and sustainable resources. To do that efficient and clean synthetic methodologies need to be developed. In this regard, the catalysis technology offers a simple and straightforward approach to achieve the synthesis of various important chemicals in an efficient, cheap, and environmentally benign way. Catalytic reactions are often associated with (multi)-electron transfer processes. Heavier transition metals usually undergo multi-electron transfer processes (Mn/Mn+2) and consequently, several industrially relevant reactions are catalyzed by these heavy metal catalysts although they are scarce, expensive and toxic. Therefore to make catalytic reactions more sustainable and environmentally benign these noble metals need to be replaced by cheap, earth-abundant and eco-friendly base metals. However, the tendency of base metals to undergo one electron transfer changes (Mn/Mn+1) makes it tough to control the reactivity and selectivity of the chemical transformations. Herein we present a simple and affordable approach of achieving multi-electron chemical transformations using inexpensive and eco-friendly base metals. Using a combination of base metals with some chosen redox-noninnocent ligands we achieved several chemical transformations like carbon-hetero atom cross-coupling, dehydrogenative coupling reactions under mild conditions which are otherwise known to be catalyzed only by noble metals. Synergistic participation of redox-noninnocent ligand during electron transfer events allow to avoid the energetically demanding metal-centered multi-step redox events and facilitate the catalytic reactions under mild conditions. Recently we developed low-cost and environmentally benign strategies for the synthesis of various biologically active and medicinally relevant organic compounds like purine, pyrimidine, quinoline, quinazoline, 4(3H)-quinazolinone etc.

Mr Himanshu AgarwalImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Meerut

college Meerut Designation : Phd student

ABSTRACT These material have applications in devices such as rechargeable batteries, sensors diode, Catalysts and etc. Hybridization of CPs with other components has been conducted to improve the sensitivity and selectivity .Classical synthetic methods produce defective polyacetylene with sp3 hybridized defects at the junction of cross-links between polymer chains.

Given that the degree of ? overlap along the chain directly determines the bandwidths (and gap) and sp3 centers decrease the conjugation, classically prepared poly acetylenes will possess larger band gaps than a more structurally homogeneous material.

Indeed, a number of theoretical studies have shown that coplanarity along the chain ? –orbitals lead to better electrical properties. these materials will have great importance in the future and have become an important material in optical studies.

Alkyl substituted polythiophenes, on the other hand, are soluble in most organic solvents. Alkyl substituted strongly influences the properties of polythiophenes, which show good environmental stability and electroactivity.

Poly-(3-alkyl thiophene)s have stirred much interest in the development of future electronic and optoelectronic devices such as light-emitting diodes( LEDs), photovoltaic and photoconductive devices, field-effect transistors, optical modulator devices and also used as a resistive touch screen. Polythiophenes have also been exploited as an electrocatalyst and in biosensor applications.

The cyclic voltammetry has been recently used for electropolymerization of 3-methyl thiophene (3-MT) in the presence of a catalyst 1-(2-pyrrolyl)-2-[thienyl] ethylene (PTE) in acetonitrile as a solvent and lithium perchlorate as the electrolyte on a glassy carbon (GC) electrode, these synthesized polymers were found to have better conductivity.

The literature survey has revealed that polythiophenes and substituted polythiophenes are a very important class of polymer with several Industrial applications. So, it is of immense importance to synthesize some new substituted polythiophenes and their composites if possible.Substituted polythiophenes will be prepared by Electrochemical polymerization.

Ms Dnyaneshwari PatilImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : K. K. Wagh

Institute of Engineering Education and Research,

NashikDesignation : Assistant

Professor

A novel colorimetric probe based on 2- aminoquinolin-3-yl phenyl hydrazone Schiff base ligand (SBL) derivatives for the detection of metal ions viz. Al3+ and Fe3+ in ethanol solution was designed and synthesized. The SBL displayed quick response to Al3+ with red shift of 34 nm at 427 nm in visible region and at 420 nm for Fe3+ over the other metal ions. SBL when titrated with Fe3+ from 0 to 100 equivalent, at 233 nm and 402 nm isosbestic points are observed with increasing concentration of Fe3+ with binding constant 3.81 X 105 M-1. This clearly shows the affinity of SBL towards Fe3+. Similar titration was carried out for Al3+ and binding constant value was found to be 8.15 x 105 M-1 by Benesi Hildebrand method. Moreover, electrochemical studies by using cyclic voltammetry were also performed to know the reversibility of complex. SBL-Fe3+ was found to be reversible after addition of EDTA, thus SBL can be effectively used as switch chemosensor for detection of Fe3+. Job’s plot method shows 1:1 stoichiometry for SBL-Al3+ complex and 2:1 for SBL-Fe3+ complex. In addition, 1H NMR titration experiments of SBL with Al3+ confirms the binding mechanism as 1:1 host guest complex.

Keywords: 2-Amino quinoline, Colorimetric probe, Fe3+, Al3+, Schiff base

Mr SAMIRAN MISRAImage Delegate ID Theme Details


Research


KharagpurDesignation : Senior

Research Scholar

A new ternary compound Cu3Cd2In was synthesized by a high-temperature solid-state method andcharacterized by single crystal X-ray diffraction, powder X-ray diffraction and energy dispersiveX-ray analysis. Cu3Cd2In is a new ordered substitution variant in cubic MgCu2 type Laves phases. Itcrystallizes in cubic space group P4132 (213) with the lattice parameter a = 7.3064(2) Å. The unitcell of Cu3Cd2In contains 24 atoms which are distributed over 3 independent crystallographicpositions. In good agreement with common Laves phases, Cu and In are forming a three-dimensionalnetwork of vertex-linked tetrahedra (Fig. 1). Cd forms a diamond-like network interpenetrating thetetrahedron network. An interesting atomic ordering of two neighboring elements Cd and In isobserved in x-ray diffraction studies and is confirmed by first principle DFT calculations. Thecalculated density of states (DOS) and crystal orbital Hamiltonian population (COHP) explain thestability and bonding characteristics in the structure of Cu3Cd2In.

Dr VIVEKANAND JADHAVImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Shri

Muktanand College, GangapurDesignation : Assistant

Professor

In recent times, heterocyclic organic compounds have witnessed tremendous growth due to their wide applications in medicinal and pharmaceutical chemistry as they show potent biological activities 1.

In addition to this, the majorities of organic reactions are generally probing danger to the environment. So to address such environmental issues2-3 by avoiding the use of hazardous chemicals, catalysts and other intermediates, in the proposed study, we are developing an environment benign method for the synthesis of 3-methyl-4-arylmethylene Isoxazole- 5(4H)-ones 1 by the one-pot cyclo condensation reaction between ?-ketoester, substituted aldehydes and hydroxylamine hydrochloride, utilizing Potassium 2-Oxoimidazolidine-1, 3-Diide4 as a novel recyclable catalyst in water as a green media within shorter reaction time. The synthesis of 3-methyl-4-arylmethylene Isoxazole- 5(4H)-ones and their derivatives that can open the doors for the future drug lead candidates against cancer, tuberculosis, and many more life-threatening diseases.

References: 1. Arif, D.; Kulkarni, A.; Bela, T., University of Massachusetts Boston, July 2011; 2. Singh, M.S; Chawdhary, S., Rsc. Advances, 2012, 2, 4547-4592 -pubs.rsc.org; 3. Polshettiwar V.; Varma R.S; Green chem., 2010, 12,743-754 4. Bahrami, F.; Nikpassand, M., Bull. Chem. Soc. Ethiop. 2018, 32(2), 399-405.

Dr Tuhin GhoshImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Durgapur

Government CollegeDesignation : Assistant

Professor

Living poly(2-dimethylaminoethyl methacrylate) (PDMA) has been synthesized by Atom Transfer Radical Polymerization (ATRP) of 2-dimethylaminoethyl methacrylate (DMA) in bulk at 30°C using CuCl/N,N,N',N',N"-pentamethyldiethylenetriamine (PMDETA) catalyst.[1],[2] Addition of catalytic amount of tricaprylylmethylammonium chloride (Aliquat®336)(AQCl) keeps the deactivator cupric complex soluble throughout the polymerization. The solubility of the charged cuprous/cupric complexes in bulk DMA is proposed through their entrapment within the ionic core of the reverse micelle like aggregates formed by AQCl in DMA medium, as observed from dynamic light scattering analysis.[3] Synthesized PDMA molecules have been successfully chain extended with different methacrylate monomers in one pot for the synthesis of various stimuli responsive, multifunctional di- or triblock copolymers.[4] An adventitious role of water molecules in respect of kinetics and control over polymerization is noted when moist monomer or AQCl is taken for reaction. References [1] Matyjaszewski, K.; Xia, J.Chem. Rev.2001, 101, 2921. [2] Coessens, V.; Pintauer, T.; Matyjaszewski, K. Prog. Polym. Sci.2001, 26, 337. [3] Starks, C. M.; Liotta, C. L.; Halpern, M. 2nd ed.; Chapman & Hall: New York, 1994. [4] Pantoustier, N.; Moins, S.; Wautier, M.; Deqee, P.; Dubois, P. Chem. Comm.2003, 340.

Ms MANSI GANDHIImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : VELLORE

INSTITUTE OF TECHNOLOGYDesignation : ICMR-SRF

(Ph.D. Scholar)

In-Sitully Immobilized Sesamol-Quinone/ Carbon Black based Electrochemical Redox Platform for an Efficient Immunosensor Applications

Mansi Gandhi,a,b Desikan Rajagopal,*b and Annamalai Senthil Kumar*a,b,c

Abstract: Most of the common redox mediators such as organic dyes and cyanide ligand associated metal complex, used for various electrochemical applications are hazardous and environmental polluting. Sesamol, a vital nutrient that exists in natural products like sesame seeds and oil, shows several therapeutic benefits including anticancer, anti-diabetic and cardiovascular protective properties etc. Herein, we introduce a new electrochemical redox platform based on a sesamol derivative, sesamol-quinone (Ses-Qn; oxidized sesamol) prepared by in-situ electrochemical oxidation method on carbon nanoblack chemically modified glassy carbon electrode surface (GCE/CB@Ses-Qn) in pH 7 phosphate buffer solution, for non-toxic and sustainable electrochemical, electroanalytical and bioelectroanalytical applications. The new Ses-Qnmodified electrode showed a well-defined redox peak at Eo = 0.1 V vs Ag/AgCl without any surface-fouling behavior. Following three representative applications were demonstrated with this new redox system: (i) simple and quick estimation of sesamol content in the natural herbal products by electrochemical oxidation on GCE/CB followed by analysing the oxidation current signal; (ii) Utilizing the GCE/CB@Ses-Qn as a transducer, bio-electrocatalytic reduction and sensing of H2O2 after absorbing the Horseradish peroxidase (HRP) based enzymatic system on the underlying surface. The biosensor showed highly selective H2O2signal with current sensitivity and detection limit values, 0.1303 ?A ?M-1 and 990 nM respectively with tolerable interference from the common biochemicals like dissolved oxygen, cysteine, ascorbic acid, glucose, xanthine, hypoxanthine, uric acid and hydrazine. (iii) Electrochemical immunosensing of white spot syndrome virus by sequentially modifying primary antibody, antigen, secondary antibody (HRP linked) and bovine serum albumin on the redox electrode followed by selective bio-electrochemical detection of H2O2. References: 1. Khairunnisa, A.; Kumar, A.S.; ACS Appl. Nano Mater.2018. 2. Kumar, A.S.; Tanase, T.; Iida,; M. Langmuir 2007, 23, 391–394.

Dr Priyankar PairaImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Vellore Insitute of Technology


Development of novel methodologies for the synthesis of Ruthenium, Iridium and Rhenium based monometallic and heterodimetallic scaffolds as cancer theranostic agents PRIYANKAR PAIRA*, NILMADHAB ROY Department of Chemistry, School of Advanced Sciences, VIT, Vellore-632014, Tamilnadu, India [email protected] Chemotherapy is the most prevalent traditional cancer therapy but it lacks tumor specificity and thus it renders normal cells at risk. So, there is considerable attention focused on the design of new metal-based drugs by following approaches including (i) selectivity in cancer cell by non-covalent modes of DNA interaction that mimic the mode of interaction of proteins with DNA; (ii) development of various photo-toxic agents as these produced reactive oxygen species (ROS) at the photo-exposed cancer cells leaving the unexposed healthy cells minimally affected. Among various photo-active molecules, wide range of derivatives of ruthenium(II)-polypyridyl complexes has already been developed; (iii) “Theranostic”, which includes simultaneous diagnostic and therapeutic functions in a single system. Theranostics improves the outcome of a disease state. With respect to therapeutic regimes, improved treatment effect is achieved by effective localization at the tumor specific sites of the therapeutic agents, whereas from diagnosis aspect imaging agents along with therapeutic agents combined with biomarkers (tumor specific markers) are carried from one system to another enabling them to differentiate the tumor cells from normal cells. In continuation of our present work on anticancer organorutheniums [1-2], herein, we have introduced the convenient and effective methodologies for the synthesis of Ru(II)-arene complexes which can addressed all three approaches. The operational simplicity, good yield, ease of isolation of the products and high chemoselectivity are the main advantages of these methods.

[1] Subran S. K., Banerjee S., Mondal A., Paira P., New J. Chem., 40, (2016), 10333-10343 [2] Sarkar B, Mondal A, Madaan Y, Roy N, Moorthy A, Kuo YC, Paira P, Dalton Transactions 48 (32), 12257-12271

Dr SHIBASHIS HALDERImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : T. N. B.

College, BhagalpurDesignation : Assistant

Professor

A cadmium(II) based two dimensional metal organic framework (MOF), [Cd(4-bpd)(SCN)2]n (1), where 4-bpd represents 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene, was synthesized by slow diffusion process and it was characterized by standard analytical methods including single crystal X-ray diffraction analysis.1 When this metal organic framework is sandwiched between indium titanium oxide (ITO) coated glass and metallic aluminium, it has been observed to exhibit remarkable conduction properties. The current-voltage (I-V) character of ITO/1/Al configuration evaluated under dark condition and in the presence of light shows a highly non-linear rectifying behavior, which establishes its character as a Schottky diode. It has been observed that the conductivity of this device configuration is 2.90 ×10-4 S m-1 and 7.16 ×10-4 S m-1 under dark and on photo irradiated conditions, respectively. It indicates enhancement of conductivity on exposure of the device to incident radiation. Various parameters of this sandwiched device have been measured and analyzed. These analyses and results indicate that 1 can be considered as a promising candidate in the field of light sensing electronic devices. The device exhibits good sensitivity towards switching “on/off” of the light source. Some theoretical calculations have been carried out to realize the reason behind the enhancement of conductivity in the presence of incident radiation. It has been observed that on irradiation, slight changes in bond distances occur in the 4-bpd moiety within the crystal of 1. These changes causes significant decline in the energy required for the permissible electronic transition. This may influence the enhancement in conductivity of the device along with some other factors.

Mr NILMADHAB ROYImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Vellore Institute of Technology

Designation : Ph.D Scholar

Development of novel Ruthenium(II) and Iridium(III) based monometallic, bimetallic and heterobimetallic scaffolds as luminescent theranostic agents in treatment of cancer NILMADHAB ROY*, PRIYANKAR PAIRA Department of Chemistry, School of Advanced Sciences, VIT, Vellore-632014, Tamilnadu, India [email protected] We are in a great menace due to unrestricted increase of second most fatal disease, cancer as we are still unable to discover appropriate medicine to defeat cancer permanently. Although there are some market available drugs, they are associated with lots of demerits in treatment of cancer and thereby losing their importance. From that point of view, our main objective is to develop i) target specific, ii) cytoselective rendering the normal cell unaffected, iii) water soluble, iv) cancer cell permeable, v) luminescent drug to get rid from the grip of cancer by using the drug theranostically, i.e. detection and destruction of cancer cell simultaneously. To achieve our goal, therefore, we have tried to prepare Ru(II) and Ir(III) based metallo drugs in treatment of cancer theranostically. The interesting feature of our scaffolds is the presence of two different metals in a same moiety which fulfill both the requirements of cancer cell imaging and killing by using only one drug at a time as the attachment of iridium metal makes the scaffold more fluorescent by shifting the emission wavelength in NIR region and compels the scaffolds to act as a good anticancer agent along with the presence of ruthenium metal. It is noteworthy that we already succeeded upto in vitro study with that scaffolds and hope it may help in cancer treatment in near future.

[1] Subran S. K., Banerjee S., Mondal A., Paira P., New J. Chem., 40, (2016), 10333-10343 [2] Sarkar B, Mondal A, Madaan Y, Roy N, Moorthy A, Kuo YC, Paira P, Dalton Transactions 48 (32), 12257-12271

Mr AJAY KUMARImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : G.B PANT

UNIVERSITY OF AGRICULTURE AND

TECHNOLOGYDesignation : RESEARCH

SCHOLAR

Hydrogel based magnetic materials display applications in cell separation, magnetic resonanceimaging and target-specific delivery of biomolecules. Drug loaded Magnetic nanoparticle's vehicle issurface-functionalized to deliver the drug at the final target destination without any hazardouseffect. Hydrogel coated ferrites impart magnetic field regulated thermo-sensitive characteristicsthat make them suitable for target delivery of biomolecules. In the present investigation, synthesisof green nanocapsules of ferrites hydrogels (FHGs) is derived from the polymer of (N-isopropylacrylamide) (NIPAM) that was conducted in a glass reactor with requisite quantity (mol/dL) ofmonomer. The process involves 2,2’-azobisisobutyronitrile (AIBN) originated in situ polymerizationof NIPAM monomers in presence of ferrites nanoparticle’s (FNPs) and bis-acrylamide (BAM)cross-linker at 90±1oC with 1200psi over 6 hr. Magnetic behavior of FNPs and respective FHGs werefound super-paramagnetic and the average crystalline size of FNPs about 19.5 nm. Poly-(N-isopropylacrylamide) (PNIPAM) characterized and investigated for the release of an anticancerous drugDoxorubicin (DOX). AIBN initiated polymerization of NIPAM in presence of BAM has afforded PNIPAMwith a pair of absorptions at 227 (weak) 245 (strong) nm. Such a blue shift in the absorption ofPNIPAM over monomer may be assigned to the loss of the unsaturation of the vinyl functionality as aresult of the polymerization reaction. Polymerization of NIPAM in presence of BAM and FNPs underidentical reaction conditions afforded FHGs with absorption at 227 nm. Such blue shift assignedbonding of amine functionality of the PNIPAM with FNPs. Ultra-violet spectrum reveals that FHGsdisplay in- vitro biocompatibility and sustained delivery of DOX up to 72 hrs at pH 7.2±0.2 and25±1oC. DOX was covalently attached to FHGs through an amide linkage. The present investigationprovides an inexpensive and green friendly method of FHGs suitable for target-specific delivery ofanticancer drugs.

Ms Naveda QuraishiImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Pt.

Ravishankar shukla university Raipur


During the last century, the consumption of energy has increased a lot due to the change in life style and the significant growth of population. This increase of energy demand has been supplied by the use of fossil resources, which caused the crises of the fossil fuel depletion, the increase in its price and the serious environmental impacts as global warming, acidification, deforestation, ozone depletion, Eutrophication and photochemical smog. As fossil fuels are limited sources of energy, this increasing demand for energy has led to a search for alternative sources of energy that would be economically efficient, socially equitable, and environmentally sound. Two of the main contributors of this increase of energy demand have been the transportation and the basic industry sectors, being the largest energy consumers. The transport sector is a major consumer of petroleum fuels such as diesel, gasoline, liquefied petroleum gas(LPG) and compressed natural gas (CNG)’ (Demirbas, 2006). Demand for transport fuels has risen significantly during the past few decades. (IEA, 2008). as first, second or third generation biofuels (OECD/ IEA 2008). Second and third generation biofuels are also called “advanced” biofuels. First-generation biofuels are commercially produced using conventional technology. The basic feedstocks are seeds, grains, or whole plants from crops such as corn, sugar cane, rapeseed, wheat, sunflower seeds or oil palm. These plants were originally selected as food or fodder and most are still mainly used to feed people. The most common first-generation biofuels are bioethanol (currently over 80% of liquid biofuels production by energy content), followed by biodiesel, vegetable oil, and biogas. Second-generation biofuels can be produced from a variety of non-food sources. These include waste biomass, the stalks of wheat, corn stover, wood, and special energy or biomass crops (e.g. Miscanthus). Second-generation biofuels use biomass to liquid (BtL) technology, by thermo chemical conversion (mainly to produce biodiesel) or fermentation (e.g. to produce cellulosic ethanol).Many second-generation biofuels are under development such as biohydrogen, biomethanol, DMF, Bio-DME, Fischer-Tropsch diesel,

Dr ARCHANA CHAKRAVARTYImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Jamia Millia

Islamia UniversityDesignation : Post Doctoral

Fellow

Archana Chakravarty*, Preeti Singh and Saiqa Ikram* Bio/Polymers Research Laboratory, Department of Chemistry, Jamia Millia Islamia University, New Delhi-110025, India. E-mail: [email protected] [email protected]

The ?eld of nanotechnology is one of the most active areas of interdisciplinary research in modern science1.Nanoparticles have multifunctional characteristic and found to have tremendous applications in the ?eld of health and medicine, electronics, transportation, energy and environment, space exploration etc. Nanomedicine makes a huge impact in health care sector in treating various chronic diseases in more safer, more effective and personalized way2. In this paper we used green synthesis rout for synthesis of bioactive nanoparticle using plants extracts because the physical, chemical methods use for the synthesis of nanoparticles generally result in low production, high expenditure as well as use of hazardous compounds such as hydrazine, sodium borohydride, and dimethyl formamide (DMF) as reducing agents which results in a more complicated and time-consuming process for removing the toxic compounds for biomedical applications. Whereas metal nanoparticles synthesized using plant extracts can minimize their toxicity due to presence of various plant metabolites like sugars, terpenoids, polyphenols, alkaloids, phenolic acids etc. they plays a major role in the bioreduction of metal ions in nanoparticles and supporting their subsequent stability. Furthermore, green synthesis of metal nanoparticles using plant extracts is a an environmentally clean, very cost effective, economical and valuable alternative to the large-scale production of bioactive metal nanoparticles within less time with low maintenance, there is no need to use high temperature, pressure, toxic chemical3-5. The aim of the present work is to synthesize silver nanoparticles by green synthesis route using plant (waste) extracts and to evaluate their bioactivity such as antioxidant, anti-inflammatory, antibacterial, anti-cancerous, anti-tumor, anti diabetics etc. biologically prepared silver nanoparticles have the potential to be utilized in therapeutic science.

Ms keerti raniImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : kurukshetra

university, kurukshetraDesignation : research

scholar

Surface Functionalized Superparamagnetic Nanoparticles Keerti Rani* and Ramesh Kumar* Department of Chemistry, Kurukshetra University Kurukshetra [email protected] Abstract: In recent years, the research and development for nanotechnology has attracted significant interest and it is still the subject for investigation. During this period, a number of research papers on superparamagnetic nanoparticles have been published. Organic and inorganic pollutants generated from different types of discarded products cause environmental problems and hence draw the attention to the scientists in recent times. The pollutants contain different types of toxic materials such as lead, cadmium and chromium [1]. Superparamagnetic iron oxide nanoparticles have attracted very much attention due to their chemical and physical properties [2]. Magnetite nanoparticles were synthesized via the chemical co-precipitation method using ammonium hydroxide as the precipitating agent. The size of the magnetite nanoparticles was carefully controlled by varying the reaction temperature and through the surface modification [3]. These nanoparticles having their surface modified with appropriate coating materials have been reported showing important applications including environmental applications, magnetic resonance imaging (MRI) contrast enhancement, hyperthermia and drug delivery. Further, their role in many other applications like tissue repair and cell separation has also been reported. Key words: Nanotechnology, Superparamagnetic Nanoparticles and Surface Modification. References: 1. R. Widmer, H. O. Krapf, D. S. Khetriwal, M. Schnellmann, H. Boni, Environ. Impact Assess. Rev. 25 (2005) 436. 2. M.V. Cagnoli, G. Pecchi, S. J. Stewart et al., Nanotech. 24 (2013) 175601. 3. K. Petcharoena, A. Sirivat, Mater. Sci. Engg. B 177 (2012) 427.

Dr Lisa RoyImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Institute of

Chemical Technology Mumbai - IOC Odisha Campus Bhubaneswar


The conversion of CO2 into liquid fuels and value-added fine chemicals is of significant interest for both environment and global energy demand. In this presentation, we highlight the viable methods for transformation of CO2 into valuable C1 feedstocks and summarize the key mechanistic aspects of the two important pathways of two-electron CO2 reduction: (i) CO2 dissociation to CO and (ii) CO2 hydrogenation to formate. Bifunctional activation processes, such as concerted PCET or MCET, are operative for CO2 dissociation to CO catalysed by base metal complexes. CO2 hydrogenation occurs through direct hydride transfer to CO2, because typically the nucleophilicity of low-valent metal centres are much lower than that of metal-hydride species. For CO2 to formate conversion, hydricity or hydride affinity of the metal di-hydride intermediate is the key player in determining the nature of the RDS. Thus, we show how theoretically obtained mechanistic insights could be translated into developing strategies for designing efficient non-noble metal catalysts for CO2 reduction.

References, 1) L. Roy, M. H. Al-Afyouni, D. E. DeRosha, B. Mondal, I. M. DiMucci, K. M. Lancaster, J. Shearer, E. Bill, W. W. Brennessel, F. Neese, S. Ye and P. L. Holland, Chem. Sci. 2019, 10, 918. 2) B. Mondal, F. Neese and S. Ye, Computational Insights into Chemical Reactivity and Road to Catalyst Design: The Paradigm of CO2 Hydrogenation. Non-Noble Metal Catalysis: Molecular Approaches and Reactions. Wiley-VcH, 2019, pp 33 - 48.

Dr Sapana JadounImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Lingayas


Professor

Modification of conducting polymers via functionalization has attracted considerable attention as itcan enhance the solubility as well as processability of conducting polymers which is a major problemdue to bulky and heavier groups attached in the material. The work highlights the synthesis of[Poly(o-phenylenediamine), Poly(luminol), Poly(naphthylamine), Poly(o-anisidine), Poly(carbazole)and their copolymers via ultrasonication, microwave-assisted, mechanochemical synthesis, green/solvent free synthesis for sustainable development along with their doping via some luminescentcompounds or via some dyes to tailor the functionality of these materials via functionalization ofmonomers before copolymerization to enhance their biocompatibility (non-toxic too) for using indifferent biological activities like binding of proteins and adsorption of Bovine Serum Albumin inbiosensing, Bioimaging of Leishmania donovani for the early detection of Leishmaniasis that is aworld-threatening disease. Some synthesized copolymers could be safely used for in vivo imaging ofcancer cells. While other copolymers from different donor-acceptor monomers are highly useful inOLEDs devices due to their electron and hole transporting nature and enhancement of their oscillatorstrength as well as their quantum yield achieved for use in near-infrared fluorescence imaging. Somedoped polymers could be used for the detection of BSA as well as Live cell imaging revealed thatthese functionalized nanopolymers showed penetration into the cytoplasm and excellent labeling of E.coli. Hence, could be used to design tunable biomarkers by tailoring the conjugated polymer whilesome are smart polymers such as stimuli-responsive, etc. for applications such as sensing. Above allwere analyzed via NMR, FTIR, UV-Vis, Fluorescence, TEM, Time-resolved spectra, CV, DTA, TGA, XRD,and molar mass determination. These types of smart conjugated polymers are highly demanding foroptoelectronic and energy applications as well as in biomedical due to their chemical structure,extended conjugation, tuned bandgap, controlled morphology, enhanced solubility, and processability.

Dr Shikha BaskarImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Forest

Research Institute, DehradunDesignation : Project

Scientist & PI-DST (SYST)

Petrochemical-based plastics have been increasingly used as packaging materials because their largeavailability at relatively low cost and because their good mechanical performance such as tensileand tear strength, good barrier to oxygen, carbon dioxide, anhydride and aroma compound, heatsealability, and so on. But nowadays their use has to be restricted because they are not non-totallyrecyclable and/or biodegradable so they pose serious ecological problems. Plastic packagingmaterials are also often contaminated by foodstuff and biological substance, so recycling thesematerial is impracticable and most of the times economically not convenient. Biomass is one of theimportant renewable sources for securing future energy supply, production of fine chemicals, andhigh value biodegradable polymers, and sustainable development. Our research is mainly devoted todesign and synthesis of green materials and biodegradable polymers from biomass for the productionof bioplastic films, bioplastic bags, and biodegradable fibers. In our research laboratory,different types of biomass (litter) have been collected from FRI Dehradun. Collected leaves werecleaned. The leaves were first air dried and then dried under oven at 40 C for 12 h. Dried leaveswere crushed to fine particles and undergone the acid hydrolysis. Mixture of sugars and lignin wereseparated. Mixture of sugars was converted into biodegradable materials under mild conditions. Thenewly developed water based bioplastic films were obtained by simple casting on a substrate (afterwashing with water) on a petri dish and drying under oven at 40 C for 24 h. The preliminary work forthe production of bioplastic films from biomass (litters) has been achieved with effectivemethodology. Preparation of biodegradable plastic bags, biodegradable fibers, and their applicationsare in progress in our laboratory.

Dr Abhishek DubeyImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Ram Jaipal

College (A Post Graduate Unit of Jai Prakash University)Designation : Assistant

Professor

Transition metal-catalyzed transfer hydrogenation (TH) of polar bonds has a great number of important applications in organic synthesis and it is a practical and convenient method for production of value-added products, such as alcohols, amines, and saturated N-heterocycles.[1] Compared to other methods such as direct hydrogenation and the use of metal hydrides, transfer hydrogenation offers a number of important advantages. It avoids the use of handling moisture-sensitive and reactive reagents, pressurized flammable gas and specialized equipment. In addition, common hydrogen donors such as alcohols or formic acid are readily available; it is inexpensive and can be safely handled. The catalysts employed in reactions of hydrogen activation and hydrogen transfer reactivity mainly rely on precious metals supported by phosphine ligands.[2] In order to develop cost effective process, replacement of precious metal catalysts with earth-abundant metal based efficient catalyst (Fe and Mn) supported by simple, robust ligands is paramount important. Inspired by nature that utilizes secondary coordination sphere interactions for H2 splitting in Fe-containing hydrogenases,[3] simple bipyridine-based Mn catalysts were developed that act as active catalysts for transfer hydrogenation of ketones, aldehydes and imines. For the first time, Mn-catalyzed transfer hydrogenation of N-heterocycles was reported. The highest catalytic activity among complexes with variously substituted ligands was observed for the complex bearing two OH groups in bipyridine. (ChemCatChem 2019, 11, 3844–3852).

Deuterium labeling studies revealed a “monohydride” pathway for TH of acetophenone and showed selective D-incorporation during the TH of N-heterocycles. Based on DFT studies, we propose the possible pathway for the complex with 6,6’- dihydroxy-2,2’-bipyridine, in which the presence of the OH group in bipyridine ligand plays a role in the hydrogen transfer steps.

Dr BABHU VIGNESH RImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Sethu Institute

of Technology, Pullaor. Kariapatti - 626 115.

Virudhunagar Dt, Tamil NaduDesignation : Assistant Professor (SG) & HOD(ic)

Aluminium based materials undergo natural process of deterioration on exposure to corrosiveenvironment. Among the strategies of corrosion control, sol-gel coatings have become popular as theyhave successfully replaced toxic hexavalent chromate coatings used hitherto. The adherent ability ofsol-gel coatings combined with their ability to prevent the access of electrolyte thereby has madesol-gel coatings a promising and valuable method of corrosion control. In the present work,3-glycidoxypropyltrimethoxysilane (GPTMS) was used as a precursor for silane based sol-gel coatings.In order to improve the active protection of metal, Allylthiourea (ATU) was introduced into thesol-gel system. The nature of the coatings was studied using FT-IR, SEM and EDX. Thermogravimetricanalysis (TGA) showed the thermal stability of the sol-gel coating. The hydrophobic nature ofsol-gel coating was confirmed using contact angle measurement by sessile drop method. The corrosioninhibition of the coated substrates was evaluated by electrochemical impedance spectroscopy (EIS)and potentiodynamic polarization (PP) techniques. From the results, ATU doped GPTMS sol-gel coatingforms an adherent layer over metallic surface which acts as significant physical barrier against theattack of corrosive ions in neutral medium.

Mr Vaibhav SawaleImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Department of pharmaceutical sciences R. T.

M. N. U. NagpurDesignation : Student

Despite the recent advances in medicine, antimicrobial chemotherapy still remains a majorproblematic in most under-developed and developed countries. An Anti-microbial agent is a substancewhich kills or inhibits the growth of microorganisms such as bacteria, fungi or protozoans. N-Mannich Bases of 3, 4-dihydropyrimidine -2(1H)-one (DHPMs) derivatives belong to an interestingclass of heterocyclic compounds which has attracted considerable attention of medicinal chemists. N-Mannich Bases of DHPMs have been considered for a variety of biological activities such asantitumor, antiviral and antioxidant activities. The main objective of molecular docking is topredict the biological activity of given ligand. The Molecular Docking study was done by usingMaestro 11.5 Schrodinger software to find the interaction between active Dihydropyrimidinone Mannichbases with DNA Gyrase (PDB ID: 1KZN) and Sterol 14?-demethylase (PDB ID: 1EA1)enzymes. Moleculardocking studies showed that Novel Dihydropyrimidinone N-Mannich bases has shown formation ofhydrogen bond and good binding affinity with some amino acid residues. Hence DihydropyrimidinoneN-Mannich Bases may inhibit the activity of enzyme Topoisomerase II DNA Gyrase and Sterol14?-Demethylaseby binding at its active site. The compounds ((DHPM-01, DHPM-03, DHPM-13)) wereshowed potent against the DNA Gyraseas compared with standard Chloramphenicol. The compounds(DHPM-03, DHPM-05, DHPM-08, and DHPM-16) were showed more potent against the Sterol 14?-demethylaseas compared with standard Fluconazole. On the basis of docking result N-Mannich bases of DHPMs maybe good Antimicrobial agents.

Dr Ramesh Babu VallabhaneniImage Delegate ID Theme Details


Research

Category : OthersOrganisation : NRIInstitute of

technologyDesignation : Professor

Image processing plays a very important role in analyzing the images of different standards. Image enhancement, image restoration and image compression are the types of image processing techniques of which image segmentation process under Image enhancement technique is utilized extensively to analyze the medical images. An image is composed of several groups of pixels. Segmentation is an image processing technique, in which different regions of an image are segregated based upon the pixel intensities available within the image. Boundary and edge based segmentations are the two types of segmentation procedures, of which, boundary based segmentation is used widely. The effects created by tumor are extremely pervasive, leading to the formation of lesions and tumors within the human body. Tissues in brain are the most complicated part of our body; a clear examination and study are therefore required by a radiologist to identify the pathologies embed within the tissue of brain. A distinguished view upon the images is manually impossible and can be subjected to operator - errors. Further, individual segmentation and identification of tumor affected region in brain are quite unavailable in a clinical MRI scanner. Due to the presence of afore mentioned hindrances, automated algorithms capable of both tumor identification and tissue segmentation processes are proposed through this research work. With the support of clustering Techniques, Support Vector Machine (SVM), automated and unique segmentation upon the brain tissues, the identification of tumors can be effectively done. These functionalities assist the radiologist in diagnosing process, extensively. Large volumes of patient images can be easily diagnosed with minimal manual intervention and non - invasiveness. The algorithms also favour for radio therapeutic planning procedures in treating the tumor region. This research work also focuses on the separation of tumor and edema regions.

Ms Magdalene WanyagaImage Delegate ID Theme Details

Image not found or type unknown


Research


NairobiDesignation : Geologist

The aim of this research is to study the relationship between seismicity and fluid circulation in a geothermal system in the exploration stage. Studies carried out on this relationship mainly are done when the injection of fluids back to the system has begun mainly in Kenya. This study will be carried out at the Paka Geothermal prospect which is located in the Rift Valley North of Lake Baringo. It is one of the shield volcanoes found in the Rift; it has a height of 1697 meters above sea level and covers an area of approximately 280 Km2. The data obtained will be analyzed for a period of four to five years. The methods used will entail the following; the determination of hypocentral locations and fault plane solutions and estimation of the seismic hydraulic diffusivity. Software’s used will include SEISCOMP 3 for data acquisition through ArcLink and SEISAN for the determination of hypocentral locations and focal mechanisms, the seismic hydraulic diffusivity will be estimated using the equation of linear growth of seismicity for a particular period of time

Mr SAGARGOUDA PATILImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Jain college of

engineering and research udyambag belagavi 590008


This paper review the existing techniques and best practices for digital investigation stages likegathering, assessing and preserving advanced digital forensic fact and chain of authority of cybercrimes. Cyber criminals are embracing new methodologies to dispatch cyber attacks inside adjustedand regularly changing digital biological systems, this article proposes To detect and analyze thesources of attacks and vulnerabilities (reasons) that permit for cyber attacks by using advancedforensic tools and technologies. and to report vulnerability and weakness that exists for attacks atend user application . The author presents a Cyber Forensics Model in Digital Ecosystems. Moving theinformation, universal cooperation, best practices and embracing new digital scientific devices,strategies and methods will be hereinafter foremost to get advanced proof, authorize authoritativecyber security arrangements, relieve security dangers, battle hostile to crime scene investigationrehearses and prosecute cyber criminals. The worldwide Digital Forensics people group shouldcontinually refresh current practices to manage cyber criminality and anticipating how to get readyto new innovative conditions where change is constantly consistent.

Mr Avesh GargImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR- Central

Scientific Instruments Organisation


Abstract: Microwave absorbing materials is currently an emerging area of research interest due to the rapid growth in electronics and microwave communication sector. In this research work, synthesis and characterization of neodymium (Nd) doped strontium hexaferrite (Sr1-xNdxFe12O19) has been reported for microwave absorption application in X-band. The Sr1-xNdxFe12O19 has been synthesized by sol gel auto combustion reaction. The structural and morphological properties have been analyzed using XRD and SEM respectively. The particle size of Sr1-xNdxFe12O19 was found to be in the nano size range. The effect of Nd doping on the magnetic properties of strontium hexaferrite has been analyzed with the help of hysteresis loop. The saturation magnetization has been decreased with the addition of Nd in strontium hexaferrite. The optimum vale of doping is found to be x=0.3 for the microwave absorption application in X-band. Keyword: Sol-Gel, magnetization, hysteresis, Microwave Absorption.

Dr ranjita ekkaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : central

Ayurveda Research Institute for Drug Development, Klokata

Designation : research officer

Concept of Virudhha Ahara(Incompatible diet) and its application in present scenario Author: Dr Ranjita Ekka MD (Ayu), PhD, Research Officer Ayurveda, Central ayurveda Research Institute for Drug Development, Kolkata, CCRAS New Delhi, Ministry of AYUSH, GOI. Introduction: Ayurveda, the Science of life. It deals with both prevention and treatment aspect of a disease. . Virudhha Ahar is a concept of incompatible diet. The concept of virudhha ahara is one of the important factors in pathogenesis of disease. Due to consumption of virudha ahara or incompatible diet a toxic substance produced called Ama. Ama is considered as one of the major pathogenetic factor for all type of disease in Ayurveda. Though Ama is structurally not a visible substance it is considered as a kind of fine micro particles produced as a result of indigested food particle due to incompetible diet. These micro particles ciculates in all channels of the body and wherever it gets obstruct it produces diseaes. The concept Ama and its interpretation can be done with autoimmune arthritis, Rheumatoid arthritis, skin menifestation, atherosclerosis etc. In old classics the virudhha ahara is mentioned in relation to availablity of diet and lifestyle of that period. But with changing of time it is required to corelate the concept with present context of diet and lifestyle. Aims and objectives: To find out the virudhha ahara concept with diet and lifestyle of present context. Material methods: Concept of Ama, mechanism of Ama production, its pathogenesis in disease, corelation of the present day diet and life style in production of Ama. Observation and result: Incidence of Ama related disease with present time diet and lifestyle. Discussion: Analytical aspect of production of Ama and formation of disease. Key Words: Ama, srotas, virudhha ahara, diet, lifestyle

Mr Amit KumarImage Delegate ID Theme Details


Research

Category : OthersOrganisation : India

Meteorological DepartmentDesignation : Scientist-C

INSAT-3DR is a dedicated meteorological satellite in the Indian National Satellite (INSAT) series, was launched on 08th September 2016. It is placed at 74°E over equator in the geostationary orbit. INSAT-3DR has two dedicated meteorological payloads namely; Imager and Sounder. Imager is a Six Channel meteorological payload operating in Six spectral bands: Visible (VIS) in spectral band 0.55-0.75µm with a spatial resolution of 1KM; Short-Wave Infra-Red (SWIR) in spectral band 1.55-1.70µm with a spatial resolution of 1KM; Mid Infra-Red (MIR) in spectral band 3.7-3.9µm with a spatial resolution of 4KM; Water Vapor (WV) in spectral band 6.5-7.1µm with a spatial resolution of 8KM; Thermal Infra-Red 1 (TIR-1) in spectral band 10.3-11.3µm with a spatial resolution of 4KM and Thermal Infra-Red 2 (TIR-2) in spectral band 10.5-12.5µm with a spatial resolution of 4KM and temporal resolution of 30 minutes. At present the receiving, processing and dissemination of imageries and derived products from INSAT-3DR is taken care by Multi-Mission Meteorological Data Receiving & Processing System (MMDRPS), which is operational at National Meteorological Satellite Centre, India Meteorological Department, New Delhi. Based on the requirement, INSAT-3DR, IMAGER payload can be operated in three modes: Full Frame Mode, Programmed Normal Scan Mode, Programmed Sector Scan Mode (Rapid Scan Mode). During Very Severe Cyclonic Strom HIKAA, INSAT-3DR was operated in Rapid Scan mode, in order to understand the physical processes involved in the formation of this tropical cyclone. As the temporal resolution of Rapid Scan is 4minutes and 30seconds the data is acquired and processed at very high resolution. This high-resolution data will also be assimilated in NWP models for Rapid Refresh run. Also, this data will be used for the reanalysis purposes.

Mr mayank mishraImage Delegate ID Theme Details


Research

Category : OthersOrganisation : visva bharati

university Designation : phd research

scholar

A study on Backward forward linkage integration in agro-processing sector in UP Mayank Mishra1, P. Kandasami2 1Phd research scholar, Department of Agriculture Engineering, Palli Siksha Bavana, Visva-Bharati, Sriniketan- 731236. 2Assistant Professor, Department of Agriculture Engineering, Palli Siksha Bavana, Visva-Bharati, Sriniketan- 731236. Abstract Agro-process Industry is the key to development for a state like Uttar Pradesh having a huge amount of household, which relies on agriculture and allied sector. Fragmented crop production pattern limits the processing infrastructure which leads to a lower level of value addition in the state. Backward, forward linkage integration is the way by which processing units can get raw material and farm producer can get the proper channel of delivery. In this study, a model of linkage integration and the gap in the channel have been identified for the development of an ideal model which can work in the field. Linkage integration in the supply chain can fulfil the need of both processor and producer with lower price fluctuations and constant supply. The result of the study shows that linkage integration can be an alternate channel in the supply chain for agro-processing units rather than a cluster-based model.

Dr Deepika SinghImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SHUATSDesignation : Assistant

Profesoor

Background: Hepatic cancer is one of deadly disease in which multiplication of cell take place in liver and major cause of cancer related mortality. The important function of NF-?B is to regulate inflammatory responses by regulating activation, survival and proliferation of cell. Subsequently, natural based products plays an important role in suppressing the proinflammatory mediators by nuclear factor-kappa B (NF-kB) pathway. Phyllanthus emblica used in the therapy of hepatocellular carcinoma. So, the current study was designed to scrutinized the protective effects of biofabricated silver nanoparticles (PEAgNPs) using Phyllanthus emblica aqueous leaves extract as NF-kB inhibitors for hepatic cancer.

Material and Methods: Fabricated silver nanoparticles using Phyllanthus Emblica aqueous extract (PEAgNPs) acts as reducing and capping agent. Biofabricated silver nanoparticles (AgNPs) were characterized by UV spectroscopy, X-ray diffraction, and Field Emission Scanning Electron Microscope with Energy Dispersive X-ray Analysis. Hepatic cancer was induced by diethylnitrosamine (a carcinogen) and further treated with PEAgNPs for 16 weeks. The anticancer effects was assessed via in vitro cytotoxic activity on HUH (hepatic cancer) cell line and by measuring biochemical parameter in the wistar rats.

Results: In this study, PEAgNPs showed peak at 418 nm in UV spectrophotometer with spherical structure and gives crystalline peak of silver in XRD pattern. Biosynthesized AgNPs significantly down-regulated the serum marker enzymes, elevated the levels of enzymatic and non-enzymatic antioxidant profile, and diminish the levels of inflammatory markers (IL-6, TNF-alpha and IL-1beta) via NF-kB pathway.

Conclusion: Biofabricated silver nanoparticles exhibited remarkable productive impacts against hepatic cancer in rats and serves as a novel targeted therapy for hepatic cancer by regulating cytokines and NF-kB.

References Singh, D.; Singh, M.; Kumar, V,; Verma A.;. RSC Advances, 2018,8, 6940-6953

Ms Hurmat KhanImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Punjabi

University,PatialaDesignation : Junior Research

Fellow

Research is an organized and systematic study of material and sources in order to discover newthings, establish facts and to reach new conclusions. The process of research came into being due toman’s seek to be at tune with his environment and also understand nature. Research is required fordifferent reasons i.e. to acquire a degree, for new body of Knowledge, to Serve Society byincreasing standard of living for Science and technology and by showing right path to society incase of social and behavioral Sciences. For a good research, your topic must have novelty and aorganized research methodology. Research methodology (RM) is a set of systematic technique used inresearch. This simply means a guide to research and how it is conducted. RM develops a critical andscientific attitude and disciplined thinking to observations. Research is of various types and totake participation in any scientific inquiry researchers need to make a effective research proposalwhich is comprises to different steps i.e. Introduction, Research Paradigm, Research Method,Preliminary Biases or Hypothesis, References. While writing the introduction part of researchproposal begin with something interesting, e.g., a quote or story, to capture the reader's interest.Introduce you question or curiosity. If your question has evolved since you have begun, describe theprocess, need and usefulness of your research and conclude the introduction part properly. Alwaysprovide a specific, clear and easy to understand research paradigm. Describe all the researchmethods and techniques and hypothesis of your study. Provide the references used for your researchproposal at the end in sequence manner. So, for a good quality of research, research methodology isan important tool. If one knows about the basics and importance of research methodology thenresearchers can write a good quality of research proposal.

Dr Nidhi NidhiImage Delegate ID Theme Details


Research


Delhi, Mata Sundri College for Women.


Will submit shortly .

Ms Kislay AwasthiImage Delegate ID Theme Details


Research

Category : OthersOrganisation : King George's

medical UniversityDesignation : pH.D student

Dyslipidemia is a major risk factor for coronary artery disease (CAD).1,2 Search for effective anti-dyslipidemic agents is on as correction of dyslipidemia can help prevent CAD. To evaluate the effectiveness of Valeriana wallichii extract and atorvastatin in modifying the dyslipidemia resulting from feeding high cholesterol diet to the rats. Three groups of male Wistar rats were fed fructose-rich high fat diet (F-HFD) for six weeks. Two groups were then given Valeriana wallichii extract and atorvastatin respectively for 30 days. Serum lipids and lipoproteins were measured. Serum cholesterol level was found to be significantly (p References: 1. Chaturvedi V, Bhargava B. Health Care Delivery for Coronary Heart Disease in India-WhereAre We Headed? Am Heart Hosp J. 2007;5(1):32-7. 2. Zhang P, Zhang X, Brown J, Vistisen D, Sicree R, Shaw J, et al. Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes ResClinPract. 2010; 87(3):293-301.

Mr TAMOGHNA MUKHERJEEImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Amity

University KolkataDesignation : Assistant

Professor

Internet in today's world has influenced the current generation to express their views on any topic in front of the world audience. By analyzing the data we try to understand difference in human and machine analysis in various situation and conditions of life. Social media being the most used platform nowadays Social platforms such as Facebook, Twitter, YouTube, LinkedIn, Google Plus etc. have provided the space for open discussion on any event which includes launching of new products, customer review on different products, product comparison based on customer feedback etc. The data that are processed through these platforms are termed as “Emotional Data”. Analysis of this kind of data plays a significant role in refining a product's quality as per global standards. Social Networking standards have seen greater application in recent times, analysis of that becomes critical as human behavior changes its course according to nature the person lives in. The current research work focuses on processing and analysis of customer feedback on a product with a view to have information regarding the quality of the product. The working algorithm is based on opinion mining through analysis of texts for classifying information in the form of six different types of word category such as Neglected word, Catalyst word, Positive word, Negative word, Inverse word and Product name. Results from the current method exhibit its potency and efficiency still there are some exceptional situation under which needs further up-gradation. Grammatical changes in the communication way vary with the variation in geometrical zones which increase the space sample which need some nuances.

Ms roohi kesharwaniImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SHUATS,

NAINI PRAYAGRAJDesignation : research

scholar

As we know at present older as well as younger generation suffered from Rheumatoid arthritis (RA) an autoimmune disorder. There are various formulation are available in market but their utilization is somehow affected due to its poor absorption and less bioavailability. The present study had been designed to develop Solid Lipid Nanoparticle based topical gel of NSAID( Etoricoxib) to overcome the above limitation. The formulations were prepared by using method Melt Emulsification and solidification at low temperature. The gel was prepared by using Carbopol & Hydroxypropyl methylcellulose (HPMC) and a comparative study were done. The formulation was characterized for its surface morphology, particle size and size distribution, zeta potential, drug entrapment efficiency and in vitro drug release. The release study were done by using modified Franz diffusion assembly It was observed that the formulation containing higher concentration of lipid (Stearic acid) led to higher entrapment efficiency as compare to other. The carbopol containing gel shows better permeability and it is more preferable to formulate the SLN based Etoricoxib gel by using carbopol with improved bioavailability.

Mr MILAN KUMAR RAULImage Delegate ID Theme Details


Research

Category : OthersOrganisation : VIPNET,

VIGYAN PRASARDesignation : SCIENCE

COMMUNICATOR

Scientific literacy has become a necessity for everyone in a world filled with the products of scientific inquiry. Scientific information is needed by everyone in order to make choices that arise every day. Everyone wishes to be able to engage intelligently in public discourse and debate about important issues that involve science and technology. In the work place too, scientific literacy is of increasing importance. More and more jobs demand advanced skills, requiring that people be able to learn, reason, think creatively, make decisions and solve problems. An understanding of science contributes in an essential way to these skills. Imparting of science education in India should have grown with the phenomenal growth in the number of universities and colleges. However, this has not happened and there has been a consistent decline in the percentage of school students opting for science after passing their high school / higher secondary examinations. There has also been a marked change in the profile of students taking up science stream. Today, high school / higher secondary students opting for science are often those with relatively low scores unlike in the past. Even the majority of the meritorious students selected for the mathematics, physics, chemistry and biology olympiads do not opt for careers in the sciences. The concept of science motivation has been recognised by the scientific community as a means to address the imbalance that exits between developed and developing countries. Although India has made remarkable progress in the scientific field since independence, it has been observed scientists, researchers and academicians as a highlighted in the several forums, that the interests of students towards basic sciences has declined considerably in India due to various reasons. Science is an endless frontier, a unique human activity without limits. The declining popularity of science and the unwillingness among the youth to take up science as a career will jeopardise India’s future. Human resource development in science and technology has become an area of concern for the Government of India today The Government of India has, therefore, decided that massive support would be provided to basic research, especially in universities so that India can contribute significantly towards advancing that frontier. In this direction, efforts will be to undertake imaginative and innovative programmes to attract the students to science and technology and enhance the number of young scientists.

Mr Noorul HasanImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Jamia

HamdardDesignation : Ph.D.

Research Scholar

Background: Cyclic nucleotides such as cAMP and cGMP is an important intracellular secondarymessenger for synaptic plasticity and memory function in animals. Therefore inhibition of cAMP andcGMP-degrading phosphodiesterases has gained interest as a potential therapeutic target for thetreatment of cognitive deficit in Alzheimer’s disease (AD). However, the role of RFM and TDF inintracerebroventricular streptozocin (ICV-STZ) induced cognitive impairment and its effect on theneuroinflammation have not been yet reported. Therefore, the objective of the present study wasdesigned to investigate the ameliorative effect of RFM and TDF against ICV-STZ induced cognitiveimpairment in rats. Material and Methods: STZ (3 mg/kg) was administered bilaterally via ICV routeon day 1st and day 3rd in rats. DPZ was used as a reference standard and RFM, TDF was infused afterICV-STZ infusion for 15 days. Furthermore, the novel object recognition task (NORT) for nonspatialand Morris water maze (MWM) for spatial memory was performed to evaluate behavioral changes in rats.On the day 22, rats were sacrificed and brain tissue (hippocampus) were isolated for estimation ofacetylcholinesterase, pro-inflammatory cytokines mediators and oxidative stress biomarkers. Results:ICV-STZ significantly impaired memory as observed in NORT and MWM, increased pro-inflammatorycytokine level and increased oxidative stress. Moreover, RFM and TDF significantly restore ICV-STZinduced alteration in neurobehavioral and biochemical in rat brain. Conclusion: The findings of thecurrent study indicate that RFM and TDF protect rat brain via multiple mechanisms and would be usedto curb cognitive deficit associated with neurodegenerative disorders such as AD.

Ms PRIYANKA KUMARIImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Bihar Agricultural UniversityDesignation : PhD

A field experiment was conducted during kharif season (2018-19) to find out the effect of nutritional modules (vermicompost and inorganic fertilizers) on growth, yield, and nutrient uptake by onion as well as fertility status. There were fifteen treatments comprised of varied levels of vermicompost and chemical fertilizers. The experiment was laid out under split plot design and the treatments were triplicated during the experiment.Yields (31.84 t ha-1) of the kharif onion crop significantly higher was observed in treatment received with 50% K through vermicompost + 50 % K through fertilizers as compared to other treatments. Similar significant effect was observed on nutrient content (N, P and K) and nutrient uptake (N, P and K).After harvest the crop, available nutrients were found that highest soil organic carbon, available nitrogen and phosphorus was observed in the soil treated with 100 % potassium through vermicompost whereas, the highest available potassium was recorded in soil receiving 50 % recommended potassium through vermicompost and 50 % recommended K through inorganic fertilizer.On the basis of results obtained it can be concluded that the nutritional modules (vermicompost and inorganic fertilizers) can substitute the potassium requirement of plant to the extent of 20-23 % and increased the yield, content and uptake of N, P and K by onion significantly over the sole use of chemical fertilizers.Integrated nutrient management system increases availability of nutrient for existing crop and improves fertility of soil to achieve higher productivity of succeeding crops. Key Words: Kharif onion, Nutritional modules, Vermicompost, Potassium, Fertility status

Dr TOGAPUR PAVAN KUMARImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-IMMT

Designation : Senior Scientist

The institute has expertise in conducting basic research and technology oriented programs in a widerange of subjects to address the R&D problems of mining, mineral and metals industries and ensuretheir sustainable development. For the last one decade, the main thrust of R&D at CSIR-IMMT has beento empower Indian industries to meet the challenges of globalization by providing advanced and zerowaste process know-how and consultancy services for commercial exploitation of natural resourcesthrough the public-private-partnership (PPP) approach. Today, CSIR-IMMT is the first choice for manymineral based industries. It is also carving out a niche in processing of advanced materials forgreater value addition and working on resource use efficiency of critical raw materials.

Dr RITESH KUMARImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-Central

Institute of Mining & Fuel Research (CIMFR)

Designation : Sr. Scientist

Education in India has deteriorated considerably during the last three decades. This has created a threat for the social structure of the country. The deteriorating education quality has also raised an alarm for the sustainable future of the country. The future young force of the country is marching ahead with lost morale. A situation of anarchy can be clearly seen in the society from the way and the amount of discontent that the youth of today is carrying due to insecure environment. Now we all talk of improving the education system that can help to create high self-esteem in young people. The education of today is not good enough to create a human being. It has the capacity and strength of building an unemployed youth force. Having observed the education system for long it can be said the present education system is a big stumbling block in the way of inclusive growth of a human being. The very purpose of education at all levels of education like elementary, primary, secondary, graduation, post-graduation and research has been losing its meaning since the commercialization and politicization of the education system started. This needs to be changed at the earliest.

Education is the key to the development process of any country. Education provides means for an integrated development of personality through training of head, hand and heart i.e. 3H’s. In India, the system of education has always been the subject of discussion. India even after 70 years of independence is struggling for providing education for all. The elementary school of education that lay the solid and firm foundation is very much neglected even today and this has been the cause of worry for India. The aim of education as envisaged in the Indian Constitution is still not realized. Though the expansion of educational units has taken place, internal transformation and qualitative improvement in education is still a distant dream. Secondary and higher education is also facing problems but of different nature which put a big question mark for India’s future. The crisis in ethical values in an individual raises doubt in the quality of education being imparted in the country.

In this paper, authors’ suggest humanistic education as a tool for reconstruction in the education system for grooming individual personality be it teachers, student-teachers or students in the interest of the nation.

Key Words: education, school/colleges, socio-academic environment, Humanistic Education Model

Ms Arpita PaulImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Manipal

College of Pharmaceutical Sciences


According to WHO, “Cancer`` is a generic term for a large group of diseases characterized by thegrowth of abnormal cells beyond their usual boundaries that can then invade adjoining parts of thebody and/or spread to other organs.” Among the varieties of cancer, breast cancer is a frequentlydiagnosed disease affecting approximately 1 million women annually worldwide. Breast cancer can bedivided into various subtypes, among which triple-negative breast cancer (TNBC) is one of the majorphenotypes. In this type, cells are devoid of both progesterone and estrogen receptors along withHER-2/Neu gene receptors. Due to which women diagnosed with TNBC exhibit exclusive disease profilehaving several other risk factors, early onset of aggressive metastasis, limited treatment, and badprognosis. Several studies have revealed that around 50% of cancers have a marked increase in theexpression of the c-MYC proto-oncogene. These oncoproteins are overexpressed in different types ofcancers, and TNBC is also one of them. c-MYC is known to be a pleiotropic transcription factor thatcan directly or indirectly help in the progression of cancer cells. Therefore, the downregulation ofthis gene expression can be an effective approach for cancer treatment. The discovery of newstrategies to attenuate cancer is a continuous effort in the life sciences field. Among theadvancements in biology, the discovery of siRNA (small interfering RNA) to downregulate theoverexpression of gene by binding to the messenger RNA (mRNA) is known to be as RNA interference.So, this ability of siRNA to inhibit specific and targeted genes can be used as a potentialtherapeutic strategy to treat several genetic diseases as well as ‘undruggable’ targets ofcancer treatment. Thus, designing an effective siRNA sequence against the mRNA of c-MYC for itssilencing can be a promising treatment for TNBC. Although siRNA is a highly potential therapeuticstrategy, its application is still deprived due to its insufficient delivery system. Both viral andnon-viral delivery systems can be used for its conveyance, but non-viral delivery systems likepolymers are widely used as ‘carriers’ for the delivery of siRNA to its site of action.Therefore, designing an effective siRNA to reduce the overexpression of c-MYC and conveying it viapolymeric nanoparticulate delivery systems to its specified site of action can be an effective wayto treat triple-negative breast cancer.

Mr Robert Lalchhanhima SailoImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Mizoram

Remote Sensing Application Centre (MIRSAC)


Planning and decision making in any context requires a deep foresight and understanding of present problems, clear-cut objectives and appropriate policies to support it. A remote region like Mizoram, infused with multi-cultural farming practices and socio-economic stature poses several challenges to meet a holistic and sustainable form of resource utilization while recognizing the need for food production in an increasing population. With majority of the state’s rural population still dependent on agriculture and its allied sector for livelihood, there still exists a wide gap between adopting sustained form of farming/crop production and the age old practice of shifting cultivation. Though there has been several policies introduced to uproot this problem and facilitate better means of livelihood, a far-fetched prospective planning to boost the economy is still the need of the hour. An amalgamative approach that harnesses the best of both technology and cultural practices has to be realized and put into action in areas like Mizoram where social-cultural sentiments are inherently embedded in natural resource utilization. Space technology and its allied spectrum of technologies like Remote sensing and Geographic Information System (GIS), often known as Geospatial technology is increasingly becoming the driving force for planning and decision making across the local to global continuum. Considering the cultural and social structure as well as available resources, the region still has potential to grow in various aspects of agriculture and horticulture despite its unique terrain and physiographic setup. One such possibility is through intervention of Geospatial technology and its use as a planning and decision support tool. The paper highlights the possibilities and prospects of using this technology in the context of improving agriculture and horticulture sector in the state, with a few case studies and projects executed for this purpose. These studies and projects mainly concentrate on productive use of wastelands and identifying suitable land uses in lieu of shifting cultivation depending on a series of criteria and carrying capacity of the available resources. The use of flexible and customizable geospatial tools and applications for iterative analysis are also explored which have proved beneficial to the users for making informed scientific decisions while planning for agriculture & horticulture development activities. The challenges in terms of implementation of the technological findings and its interventions are also discussed.

Mr Avirup BiswasImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Manipal

College of Pharmaceutical Sciences


Biofilm is a sessile community of bacterial cells encompassed by the self-secreted hydrated matrixof polysaccharide and protein, forming a slimy layer. Biofilm is formed by bacteria that are adheredto biotic and abiotic surfaces like cochlear implants, catheters, dental implants, and pacemakerstents. Multidrug resistance develops in biofilm cells because of the multicellular nature ofbiofilm, which facilitates horizontal gene transfer. The presence of water channels in the biofilmhelps to carry bulk fluid in convective flow and deliver nutrients to most of the biofilm. Whenbacterial cells are dispersed from this niche, they become vulnerable to antibiotics that show thatthe antibiotic resistance is a functional characteristic of biofilm formation and not due to anymutation. Biofilm makes the bacteria ten to thousand-fold less susceptible to anti-microbial agents.Delivery of antimicrobials using liposomes or nanoparticles helps in drug penetration into thebiofilm and controlled release of the drug. Liposome bilayer structure resembles that of thebacterial cell wall; therefore, its easy for the drug entrapped liposome to fuse with it and releasethe drug. The main objective here is to formulate nanoliposomes and PLGA nanoparticles withfluoroquinolone antibiotics, namely Moxifloxacin and Gemifloxacin and evaluation of the formulationusing various assay Like Minimum Inhibitory Concentration, Minimum Biofilm Inhibitory Concentration,Minimum Biofilm Eradication Concentration with further in vitro and in vivo assay for the assessmentof the formulation. Crystal violet staining was performed on S.aureus (MTCC96) and P.aeruginosa(NCIM 5029) to determine their biofilm-producing capability, by cut off optical density (O.D.c) andit showed that both the strains showed biofilm-producing capability. Liposomes were also prepared byfilm hydration method, and their physical characteristics such as particle size and zeta potentialwere evaluated.

Dr Shvetank BhattImage Delegate ID Theme Details


Research


UniversityDesignation : Professor

Neuropharmacological Profiling of Sesbania grandiflora (L.) Pers. Leaves in Rodent Models of Depression and Comorbid Disorders Such as anxiety Shvetank Bhatt*1, Rajitha Kolli2, Srilakshmi Bada2 1Amity Institute of Pharmacy, Amity University Madhya Pradesh, Gwalior M.P., India- 474005 2Faculty of Pharmacy, MS Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India- 560054 Email of presenting author: [email protected] A B S T R A C T Background: Sesbania grandiflora (L.) pers. is an important drug in traditional system of medicine and is also known as agati. Sesbania grandiflora (L.) Pers. used in traditional medicine for the treatment of cold, feaver, stomach disorder, diarrhea and jaundice and as a skin cleanser. The present study was designed to evaluate the effect of ethanol extract of Sesbania grandiflora (L.) Pers. leaves in rodent models of depression and anxiety. Methodology: The protective effect of ethanol leaves extract of Sesbania grandiflora (L.) Pers.(500 mg and 1000 mg/kg, p.o.) and fluoxetine (20 mg/kg, i.p.)Using behavioural models for depression and anxiety like Chronic Unpredictable Mild Stress (CUMS) in Wistar albino rats and Swiss albino mice of either sex weighing between 200-250 gm. (rats) and 25-30 gm. (mice) were randomly selected for the study. The parameters evaluated were levels of catalase, reduced glutathione (GSH), with other oxidative stress parameters and total proteins. Results: Test drug (500 and 1000 mg/kg) exhibited antidepressant like effects in CUMS after treatment without any significant effect on spontaneous locomotor activity. After induction of stress and treatment various behavioral models like FST, TST and EPM, MBB model are performed. Significant increase in the levels of GSH, catalase and total protein and significant effect in behavioral models has been observed. Conclusion: The study revealed that ethanol leaves extract of Sesbania grandiflora (L.) Pers. showed significant anti-depressant and anti-anxiolytic. Further studies will be required to find out the exact mechanism or the active constituents involved. In addition to develop brain immunohistochemistry and gene involved in depression. References • Radhika, J., Christia, R. and Jothi, G., (2014) Effect of the Aqueous Extract of Sesbania Grandiflora Linn in Alloxan Induced Diabetes in Albino Rats, World J Pharm Res., 3, pp. 677¬685.

Mr Shivanshu GoelImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-Central

Scientific Instruments Organization


Composites based on barium hexaferrite and activated carbon are developed for RADAR absorptionapplication in X-band (8-12 GHz) frequency region. Barium hexaferrite nanoparticles are synthesizedvia sol-gel auto-combustion reaction using citrate precursors. Activated carbon is synthesized viagreen route from banana peel. Developed materials are characterized for structural analysis andsurface morphologies using SEM and XRD techniques. The hysteresis loop of barium hexaferrite showshigh value of saturation magnetization. Composites based on barium hexaferrite and activated carbonare developed using ball milling method. The composites are casted into pellet of X-band size andtested for magnetic and dielectric properties. As a result of addition of activated carbon in thecomposite the magnetic losses and dielectric losses are improved, which signifies that the compositematerial behaves as an X-band microwave absorber

Ms lata poteyImage Delegate ID Theme Details


Research

Category : OthersOrganisation : department of

pharmacutical sciences, nagpur 440033

Designation : assistant professor

Quinazolinone scaffold and its derivatives have been reported to possess diverse pharmacologicalactivities like with antibacterial, antifungal, anti-HIV, CNS depressant antitubercular, anticancer,antioxidant, bronchodilatory activity, analgesic, anti-inflammatory, anticonvulsant and antiviralactivities. Taking lead from a naturally occurring quinazoline alkaloid vasicine and Vasicinoneshowed potent bronchodilatory activity comparable to theophylline both in-vitro and in-vivo. Keepingin view the importance of this vasicinone moiety it is a versatile lead molecule for the design ofpotential bioactive bronchodilatory derivatives, an attempt has been made to synthesize noveltricyclic quinazolinone derivatives and evaluated for bronchodilator activity in -vitro by usingisolated guinea pig tracheal chain. The series of12-oxo-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline-2,4-bis-amino-2’-substituted methylcarboxylic acid derivatives 103 a-e have been prepared from 3,5-dibromo anthranilic acid and ?-caprolactam .The chemical structures of all12-oxo-6,7,8,9,10,12-hexahydroazepino[2,1-b]quinazoline-2,4-bis-amino-2’-substituted methylcarboxylic acid derivatives 103 a-e have been elucidated by spectral studies (IR, 1H NMR and Mass).All synthesized compounds have been evaluated for bronchodilator activity in -vitro by usingisolated guinea pig tracheal chain, precontracted with acetylcholine compared to standard drugtheophylline. The compound 12-oxo 6,7,8,9,10,12- hexahydroazepino[2,1-b] quinazoline-2,4-bis(2’-amino-4’-methyl pentanoic acid) 103-c and 12-oxo 6,7,8,9,10,12- hexahydroazepino[2,1-b]quinazoline-2,4-bis (2’-amino- 3’-{4-hydroxyphenyl}-propanoic acid) 103-d was found to exhibitoptimum bronchodilatory activity among all synthesized compounds.

Ms Meenakshi NegiImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Department of

Pharmaceutical Sciences, Hemvati Nandan Bahuguna

Garhwal UniversityDesignation : Ph. D. Scholar

COMPUTER-AIDED DRUG DESIGN: ROLE IN MODERN DRUG DISCOVERY Meenakshi Negi1*, Abdul Faruk1, Pooja Chawla2 1Department of Pharmaceutical Sciences, Hemvati Nandan Bahuguna Garhwal University, (A Central University), Srinagar (Garhwal), Uttarakhand-246174 2Department of Pharmaceutical Chemistry, Indo Soviet Friendship College of Pharmacy, Moga, Punjab-142001 Corresponding author’s e-mail: [email protected] Abstract: Computer science has made a massive impact in innumerable fields from product manufacturing to sales and marketing. The discovery of Cambridge Structural Database and Protein Data Bank in 1970s, lead to an escalation in computer-based pharmaceutical research and development. The combined application of molecular graphics, computational chemistry, as well as chemical and biological information is commonly called computer assisted drug design. These computer based approaches promise to fulfil a long-coveted goal of medicinal chemists: the prediction of biological activity prior to extensive laboratory synthesis and biological testing. Computational techniques include two approaches: structure based- and ligand based- drug design (SBDD and LBDD). SBDD includes methodologies like structure-based virtual screening, pharmacophore modeling and de novo design. Molecular docking and molecular dynamic simulation tools used in SBDD provide an insight into the ligand-receptor-interactions and their thermodynamics. The docking softwares like AutoDock, GOLD, Schrodinger Glide, GemDock has made it possible for the researchers to develop novel targeted therapies. One of the promising applications of innovative CADD approaches is in the identification and designing of novel validated immune small molecule modulators which may act as a boon to next generation cancer immunotherapy drug discovery. Thus, in the current era of surge of diseases, CADD is a worthwhile tool expediting the discovery of novel promising drug candidates with a substantial impact on pharmaceutical design, discovery, and development, improving the efficiency and minimizing the costly late-stage clinical trial failures. References: 1. Singh, B.; Mal, G.; Gautam, S. K.; Mukesh, M. Computer-Aided Drug Discovery. Advances in Animal Biotechnology. 2019, 471-48. 2. Acurcio, A. C.; Scomparin, A.; Satchi-Fainaro, R.; Florindo, H. F.; Guedes, R. C. Computer-aided drug design in new druggable targets for the next generation of immune-oncology therapies. WIREs Comput Mol Sci. 2019, 9, 1-27.

Dr Jai TawaleImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-National

Physical LaboratoryDesignation : Technical

Officer

ZnO and SnO2 nanostructures with different morphology have been widely used with graphene sheets to prepare the composite materials. Nanoscale synthesis of nanocomposites that possess superior properties of both semiconducting oxide nanomaterials and graphene sheets, holds potential to increase the efficiency of functional devices such as Li-ion battery devices, solar cells, photovoltaic devices and humidity sensors [1,2]. With varied fascinating nanostructural morphology of ZnO, SnO2 like nanosheets, nanorods, spherical, nanobelt, tetrapod and nanowires makes it important material to be used for nanocomposites. The present work reveals synthesis, characterization and application of oxide based graphene nanomaterials. ZnO Tetrapods and SnO2 nanostructures were prepared by thermal evaporation. The oxide nanostructure (ZnO, SnO2) based composites with graphene (SnO2/Graphene, ZnO-T/Graphene and SnO2/ZnO-T/Graphene) were synthesized using simple chemical route from a mixture of few layer graphene (FLG) and SnO2 and ZnO-T nanostructures via sonication and centrifugation. The as synthesized composites structures were characterized by X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscopes (SEM), High resolution transmission electron microscope (HRTEM) and photoluminescence spectroscopy. A structure-property correlation of these composite nanostructures has been studied with possible mechanism. Further these oxide nanostructure based graphene composite are investigated for humidity measurements.

References: 1) T. Fu, J. Zhu, M. Zhuo, B. Guan, J. Li, Z. Xu, B. Lu, Q. Li, J. Mater. Chem. C, 2014, 2, 4861-4866. 2) L. Li, K. Yu, J. Wu, Y. Wang, and Z. Zhu, Crystal Research and Technology, 2010, 45, 539-544.

Dr SREENIVASA RAO JARAPALAImage Delegate ID Theme Details


Research

Category : OthersOrganisation : ICMR-NIN

Designation : Scientist/Deputy Director

Abstract: Micronutrient Malnutrition (MNM) is one of the major public health and socioeconomicproblem at global level. India, the second largest in food production, is ranked 103rd out of 119countries according to global hunger index (GHI) 2018. Majority of Indians suffer from various dietrelated diseases includes diabetes, cardio vascular diseases, obesity and many more. The foodproduction and consumption is another biological threat and depletion of water resources among thebiodiversity is the biggest challenge to the future generation. Micro greens (MGs): The newminiature vegetables packed with more nutrients is an alternative for this problem for nutritionalsecurity, if include in diet they help to overcome malnutrition problems. MGs can be easily grown insmall areas and benefit to urban livelihood and consumers itself can grow them without any specialeffort they also contribute a greener shade to the environment. MGs are young vegetables which fallin an intermediate between sprouts and baby green. Mgs harvested generally 7-21 days after sproutingas shoots. Three basic parts- a central stem with two fully developed cotyledons and two youngleaves. They are used by chefs across global nations as garnishing agents. MGs have an aromaticflavor and are available in vivid colors. They are highly concentrated with nutrients likeantioxidants, rich in minerals, vitamins and protein. Studies show MGs possess five times moreessential nutrients compared to matured plant. MGs have low nitrate content which is advisable toinclude them in human diet especially for kids. MGs lowers liver cholesterol there by reducescardiovascular disease and NCDs. Our study proven that MGs are highly nutrients than their counterparts. The retention of nutrients from recipes developed at our laboratory is more favor thanmatured greens. Policy makers need to focus on this unmapped area of research and promote at groundlevel to eradicate malnutrition problem. The elevated level of nutrients in MGs can be used ashealth promoting approach to meet the provisions for elementary dietary intake. Comprehensiveresearch is needed to characterize improved micronutrient status in MGs. There is an emerging needto focus on this area and require furnishing emphasis towards food security, food safety, foodsustainability and nutrition security in India.

Mr Pallab GhoshImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Jadavpur

University Designation : Ph.D Scholar

Effect of Arm Swing on Vertical Jump Performance

Mr. Pallab Ghosh Research Scholar, Dept. of Phy.Edu. Jadavpur University Kolkata. [email protected]

Dr. Papan Mondal Asst. Prof. Dept.of Phy.Edu. Jadavpur University. [email protected]

ABSTRACT

INTRODUCTION: A vertical jump is a movement that is used in a plethora of sports. The primary goal of a vertical jump is normally to reach the greatest possible height.The purpose of this study was to analyze the effect of arm swing on vertical jump performance. .OBJECTIVE: 1. To compare effect of arm swing and without arm swing on vertical jump performance of university level players. 2. To know the effect of power on arm swing and without arm swing vertical jump of the university level players. 3. To find out the relationship between power and arm swing vertical jump of the university level players. METHODOLOGY: 4 Volleyball (20.29 ± 1.38 years, 179 ± 4.54 cm and 67 ± 4.34 kg) , 4 Basketball (23.43 ± 2.57years, 170.57 ±3.15cm and 62.13 ± 7.58kg) & 4 High Jump (21.75 ± .95 years, 170.37 ±3.15cm and 64.75 ± 2.21kg) university(Jadavpur university) level players were selected randomly as the subjects. Canon DSLR 1200d operating at 50Hz was used to record the movement. The identified clips were analyzed with the help of KINOVEA 0.8.24 motion analysis software. Student-t test & Pearson Product Moment Correlation Test (p RESULTS: The result of study revealed that there were significant differences (t-4.17*) between arm swing (56.67±4.86 cm) and without arm swing (43.21 ±4.23) vertical jump performance of high jump players and vertical jump performance of the volleyball & basketball players were found no significant difference but positive effect showed. Also the results showed that in power (ground reaction force) there were no significant differences found between arm swing and without arm swing of the university level players. There were also positive relationship found in Volleyball (r-0.61), Basketball (r- 0.89) & High jump (r- 0.84) University level players between power and arm swing vertical jump performance. CONCLUSION: Arm swing positively effect on the vertical jump performance for Volleyball, Basketball and High Jump players. Arm swing also positively effect on increased the power which in turn help to increased the jumping height of Volleyball, Basketball and High Jump players. It also concluded that there is positive relationship between power and with arm swing in vertical jump performance. ------------------------------- Keywords: Video Camera, Vertical Jump, Arm Swing, Players.

Prof Kailas AhireImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Chhatrapati Shahu Institute of Business Education and Research,

KolhapurDesignation : Assistant

Professor

Social networking sites have rapidly become very popular and it has one of the most usedcommunication methods in today’s world. The present study aims to examine and highlights the useand overall impact of social networking sites on student’s life. In order to collect the primarydata from students and their parents, the convenience sampling method was used for the selection ofrespondents from different parts of Kolhapur City. After the analysis of data, it can be concludedthat the visit on social networking sites has a daily routine of many students. While moreengagement on social networking may make an adverse impact on student’s behavior and health aswell, however, some students utilized it for their study purpose. It was also observed that most ofthe parents are not aware of the activities of their children on social networking sites. It isimportant to provide proper guidance and awareness about the appropriate use of social networkingsites and its overall impact on them

Ms Manna LeghuImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Kerala

University Designation : Research

Student

During my internship, I worked with ICCONS (Institute for Communicative and Cognitive Neuro Sciences, Kerala) where I gained experience and insights on the field of neurodevelopmental disorders. It has always been in my interest to share my encounters with real cases and conditions with my local community, wherever it makes a difference. The aim is to foster advocacy and increase public awareness about disabilities, decreasing the barriers for people with disabilities within my community. I plan on creating materials with the objective of educating families, medical and professional and child care providers about childhood developmental milestones and early signs of neurodevelopmental disorders including autism spectrum disorders, learning disability, intellectual disability, attention deficit hyperactivity disorder and cerebral palsy. This relates to the mission of the government by addressing the desire to diagnose delays and identify needs of children in early development and implementing programmes at the grass root level within local communities.

Ms Ankita SharmaImage Delegate ID Theme Details


Research


Geology, HNBGUDesignation : Research

Scholar

The quantitative analysis of the watershed has been carried out through the study of geomorphicindices. This type of study is relevant to the interpretation of the tectonic nature of thewatershed. The present study highlights the significance of Digital Elevation Model (DEM) for theextraction of drainage and assessment of morphotectonic indices of Asan watershed located in DoonValley, Uttarakhand, India. Also, the geomorphic indices used in this study include severalmorphotectonic parameters like basin asymmetry index, basin shape index, channel sinuosity index,hypsometric index, stream length to height ratio. Watershed dynamics is controlled by geomorphicindices which include both surficial and sub-surficial characteristics of it. Evaluation andapplication of various geomorphic indices helped us in deciphering the tectonic setting of the Asanwatershed. The overall conclusion states that the geological structures such as faults and thrustspresent in the watershed are affecting the shape of the longitudinal profile and the stream lengthto height ratio. Lithological discontinuities and tectonic uplift have resulted in the developmentof knick-points and an anomalously high SL-index value. Basin asymmetry index provides valuableinformation about the presence of tectonic tilt in the area. The shape of the watershed is elongatedand tectonically active revealed by basin shape index. The Hypsometric integral infers that thewatershed is prone to fluvial erosion dominantly. This also indicates that the watershed is highlysusceptible to tectonic events and dissected stream network. The mainstream follows the braidedcourse and is reflected through the Channel Sinuosity index. The overall tectonic analysis providesvaluable information about the geological status and evolutionary history of the watershed.

Dr Rajasekaran RajamoorthyImage Delegate ID Theme Details


Research

Category : OthersOrganisation : SNS College

of TechnologyDesignation : Associate

Professor

Cancer is becoming an incurable disease and this disease causing panic to people who live in thetiny planet. Not only the unhealthy even every age group has been victim to any type of cancer whichis ever recorded. There are many ways to cure the cancer which are Chemotherapy, Immunotherapy,Radiotherapy, Targeted Therapy or Hormone therapy. The proposed system is introducing a new way tocure the cancer by using linguascopy technique where the Cancer is removed in a mechanical waywithout open surgery. The cancer cells are targeted at particular part of the body and a catheter isused in this process to remove the cancer cell. At the posterior end a stepper motor is used tocreate a vacuum to suck out the cancer engulfed by the mouth of the catheter. The mouth of thecatheter is modified into anaconda’s mouth where the detecting sensors is used to detect cancercell colony and a tongue like structure which engulfs the cells which is made up of shape memoryalloy which contracts and expands near the cancer cell . The cell engulfed into the catheter brokendown into small pieces when it comes to its original size and it is sucked out by the vacuum createdby the stepper motor .Thus the scope is taken out of the body without damaging the organs or anybones of the body which is cost effective than other therapy to treat cancer. The proposed systemanalyze the performance stepper motor by various parameters included stepping angle, speed, torque,current and real power. The MATLAB / Simulink environment is preferred to analyze the parameters ofstepper motor.

Dr Ramu GandikotaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Institute of Aeronautical EngineeringDesignation : Associate

Professor

In the traditional method, we follow a one-size-fits-all strategy, in this, the treatment andprevention are based on the average person. Personalized Medicine potentially enables patient carewith the most suitable medicine and utmost safety measures which will replace traditional trial anderror treatment. This strategy allows physicians to prognosticate the disease with high precisionand suggest therapy and prevention approaches based on the patient’s health, personal informationand related groups (nearly matched DNA and already treated for particular disease). With the growthof artificial intelligence, several humanistic smart methods are intended to give services withbetter quality, like intelligent healthcare, emotional communication, and so many smart systems. Thecognitive computing is the essential technology to drive above smart systems. In this paper, weintroduced a PM2C framework to analyze the patient’s body nature using his DNA and ElectronicHealth Records(EHRs) and suggests the right drug at the right time with the right dosage. Here,Cognitive computing plays a vital role to analyze the DNA sequence and EHRs with a hugeheterogeneous database. It enables the patient to receive early diagnoses, risk assessments, andoptimal treatments and also improves health care at low cost

Dr Malaya Kumar NathImage Delegate ID Theme Details


Research

Category : OthersOrganisation : NIT

PuducherryDesignation : Assistant

Professor

Early detection and treatment are important to prevent the vision loss due to glaucoma. This retinal disease is mainly characterized by optic nerve fibre loss, due to increased intraocular pressure (IOP). Glaucoma can be evaluated by monitoring the IOP, visual field and optic nerve head. IOP measurement is found to be neither specific nor sensitive enough to be an effective glaucoma indicator since visual damage can be present without increased IOP. A requirement of special equipment, which is usually present only in hospitals is needed for the visual field testing method. Moreover, the test is time consuming and information obtained may not be reliable. Optic nerve head examination involves measurement of the cup to disc ratio and is considered one of the most valuable methods of structural diagnosis of the disease. However, most current algorithms for automatic glaucoma assessment using fundus images rely on handcrafted features based on segmentation, which are affected by the performance of the chosen segmentation method and the extracted features. Such methods do not perform equally well on a wide variety of datasets. Considering the limitations of various approaches, glaucoma detection using convolutional neural network (CNN) is proposed. CNNs has the unique capability of implicitly extracting discriminative features in an image and optimally combining these features for classification purposes. The proposed system employs five different ImageNet-trained models such as VGG16, VGG19, InceptionV3, ResNet50, and Xception for automatic detection of glaucoma from fundus images. The architectures are fine-tuned and the last fully connected layer of each CNN is replaced with a global average pooling layer, followed by a fully connected layer of two nodes representing two classes and a softmax classifier. The proposed approach has been examined on publicly available databases such as DRISHTI, and HRF. Using Xception architecture, the highest classification accuracy of 87.12%, and 63.33% is obtained for DRISHTI, and HRF database, respectively. The results obtained from the proposed approach are supported by an extensive cross-testing validation. Currently working on techniques to improve the classification accuracy by varying the hyperparameters. The experiments demonstrated the feasibility of deep learning technology in grading glaucoma severity. These results suggest that using ImageNet-trained models is a robust alternative for the automatic glaucoma detection system.

Ms Sanghamitra SarkarImage Delegate ID Theme Details


Research



Professor

Commercial Centres are focal points of economic, social, cultural and administrative services of the city. Urban development is the process of growth of an area situated in a city symbolized by physical, social and economic development. Evolution of Commercial Centres leads to transformation of economic and social activities leading to changes in Urban Development trajectory of a city. The study of evolution of Commercial Centres goes back to the start of human settlements and has undergone parallel development both in West and East. The West has witnessed development of Greek Agora to Medieval streets to contemporary shopping malls. Similarly, marketplaces in the East, especially in India, with history dating back to the Indus Valley civilization, were not only venues for trade but also centre for political, cultural and social interactions. In present day context, with advent of globalisation and rapid urban development, Commercial Centres have undergone transformation in scale, function, usage pattern, architecture etc. and developed prototype shopping malls which are vastly different from traditional Eastern market typologies. This enormous development drive has brought forward various urban problems especially in the Indian context. These problems range from increase in urban poverty, polarisation of money and power, transformation of urban landscape with mega projects dictating development, influenced consumption patterns of people to loss of identity of Indian cities. This paper aims at understanding the intrinsic nature of Indian Commercial Centres and identifying parameters that influence spatial transformation of the same. The objectives are firstly, to study evolution of Commercial Centres both in Western and Eastern contexts. Secondly, to understand urban form of Commercial Centres suitable for Indian cities. Thirdly, to derive corresponding parameters influencing evolution of Commercial Centres in Indian cities with critical evaluation from an urban design viewpoint in order to pave the path for holistic development and transform the image of Indian Commercial Centres.

Mr SAURAV KUMARImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-CSIODesignation : SCIENTIST

Water hyacinth (Eichhornia cassipes) is one of the worst aquatic plant in the world. It imposes both physical and ecological problems and has ecological problems and has an economic impact also. The uneven mats clog waterways making activities like: boating, fishing and almost all other things impossible. We can only minimize its spread by utilizing different available methods as well as its application for our benefit. The ever burgeoning population of water hyacinth as well as its impact on the society has made it indubitably one of the most annoying weeds of the tropics. In the present study, most notorious aquatic weed (water hyacinth) has been chosen and the area of study is focused for an Indian lakes situated at 26°16?N-27°1?N latitude & 84°30’E-85°16’E longitude. The arc-GIS image were processed by the novel method and the apparent area covered by the water hyacinth can determined. Experimentally, area of biomass available in each unit area is available which may provide a quantitative data of biomass. The various application of the water hyacinth showed in this study shows its economic potential as well.

Mr Suman MandalImage Delegate ID Theme Details


Research


university KolkataDesignation : Assitant

Professor, School of Architecture and Planning

Abstract: Effective transportation systems are of utmost importance, for the spatial/physical, environmental, economical and social progress of a metropolis. In contrast, lack of proper traffic and transportation facilities, go a long way in retarding the overall development process of a city. The impact of transport system on urban development has been proved to be the most crucial one due to the impingement of various related factors, acting as catalytic components, over a considerable period of time.

In this paper an attempt has been made to understand the relationship between transport systems and urban developments, considering Kolkata as case study. The same has been done studying through Pre-independence, Post-independence and Post-reformed economy phases. The Pre-Independence phase of urban development of Kolkata started in a most haphazard and irregular manner but later evolved in a planned way directly influenced by British transport oriented planning system. The Post-Independence phase of urban development of Kolkata, started with an impending crisis of partition, migration and deterioration of the city environment. The initial level of all the public interventions, to arrest this deteriorating situation were not entirely successful. A large amount of public investment was made only to assess and to check the existing deteriorating conditions by providing basic civic facilities. The Post-Reformed Economy phase has been fueled by the imperatives of economic liberalization, globalization and political ambition, thereby lifting the overall image and making Kolkata a global city.

In this paper a further attempt has been made to establish how lack of an efficient mass transportation system, over a long period of time, has resulted in serious deficits, in terms of comprehensive urban developments and how eventually through the introduction of mass rapid transit system, the overall quality of the transportation network boosted, thereby improving quality of overall urban development of Kolkata.

Mr Abhiroop DasImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Om Dayal

College of ArchitectureDesignation : Assistant

Professor

Effective transportation systems are of utmost importance, for the spatial/physical, environmental, economical and social progress of a metropolis. In contrast, lack of proper traffic and transportation facilities, go a long way in retarding the overall development process of a city. The impact of transport system on urban development has been proved to be the most crucial one due to the impingement of various related factors, acting as catalytic components, over a considerable period of time.

In this paper an attempt has been made to understand the relationship between transport systems and urban developments, considering Kolkata as case study. The same has been done studying through Pre-independence, Post-independence and Post-reformed economy phases. The Pre-Independence phase of urban development of Kolkata started in a most haphazard and irregular manner but later evolved in a planned way directly influenced by British transport oriented planning system. The Post-Independence phase of urban development of Kolkata, started with an impending crisis of partition, migration and deterioration of the city environment. The initial level of all the public interventions, to arrest this deteriorating situation were not entirely successful. A large amount of public investment was made only to assess and to check the existing deteriorating conditions by providing basic civic facilities. The Post-Reformed Economy phase has been fueled by the imperatives of economic liberalization, globalization and political ambition, thereby lifting the overall image and making Kolkata a global city.

In this paper a further attempt has been made to establish how lack of an efficient mass transportation system, over a long period of time, has resulted in serious deficits, in terms of comprehensive urban developments and how eventually through the introduction of mass rapid transit system, the overall quality of the transportation network boosted, thereby improving quality of overall urban development of Kolkata.

Ms Ruchira DasImage Delegate ID Theme Details


Research


UniversityDesignation : PhD Scholar

Vitality in a neighbourhood is conceptualised as a resultant of active street life (Jacobs, 1961), through provision of mixed use development, fine grain, higher density and permeability (Rowley, 1996; Strenberg, 2000), presence of diversity, density, accessibility and liveliness (Zeng et al., 2018) and human activities, in addition to function, are suggested as contributors to enhanced vitality in urban spaces (Rossi et al., 2015). The concepts of “city vitality” and “livable communities” form the cornerstones of the current discourse on “new urbanism” (Deitrick and Ellis, 2004; Nelson et al., 2004). Colonial towns of Little Europe is, approximately a 30 km stretch along the west bank of River Hooghly, and the site of former colonial settlements of the Bandel (Portuguese), Chinsurah (Dutch), Chandernagore (French) and Serampore (Danish). This area is a silent spectator and witness of many ups and downs, upheavals through the river bank and settlements for trade and power (Das, Chattopadhyay, 2014). It is selected as a case study because of its prevailing unique colonial neighbourhood character. In the recent past, an uncontrolled, sporadic and piece meal development is creating non – contextual urban devlopment, leading to a general placelessness, and degrading the vitality of these neighbourhoods. An attempt has been made to understand the phenomena of current development situation from an urban design viewpoint. Primary data collected from the neighbourhoods of Little Europe has indicated the critical issues of the places that can be considered further in design process for suitable interventions. Thereafter, identification of parameters that contributes towards of neighbourhood vitality has been done. A relationship between the selected parameters has been established using quantitative and qualitative techniques. Finally it has been envisaged that these rapid assessment tool would contribute towards attaining the inclusive developmental goals in these urban settlements by a bottom-up approach.

Dr Weeqar Younis RajaImage Delegate ID Theme Details


Research


Pharmaceutical sciencesDesignation : Assistant

Professor

Background:Hyperlipidemia is a metabolic condition that determines the onset of chronic degenerative diseases such as atherosclerosis. Problem:Currently available hypolipidemic drugs have been associated with a number of side effects and there is always a need for developing novel drugs with higher efficacy and fewer side effects. Herbal drugs are well for their cost effectiveness and minimal side effects. Viburnum Cotinofolium. D.don is one such plant with known traditional claim in the treatment of hyperlipidemia. The focus of the current study was to evaluate the antihyperlipidemic effect of methanol extract of Viburnum Cotinofolium. D.don. Methods: Hyperlipidemia was induced in male albino rats. Aqueous leaf extract of A.altissima (200 and 400 mg/kg/Day) was administered as test drug. Atorvastatin (10 mg/kg/Day) as the standard. Serum lipid profile, Liver and Cardiac risk factors were estimated. Results: The results revealed methanol extract showed significant decrease in total cholesterol (61.5 mg/dl), triglycerides(92.33 mg/dl), LDL(16 mg/dl), VLDL(18.5 mg/dl), SGOT(163.833), SGPT(59.5) and total bilirubin (0.366 mg/dl) and significant increase in HDL(26.33 mg/dl) as compared to standard Atorvastatin. The isolation of methanol extract of Viburnum Cotinofolium. D.don leads to new compound olean-11-en-3?-ol-3-O-hexadec-5?-en-1?-oate which was reported first time from Viburnum Cotinofolium. D.don which was characterised by using different spectroscopic techniques. Conclusion: Further hypolipdemic effect need to be confirmed on -11-en-3?-ol-3-O-hexadec-5?-en-1?-oate by using in- vivo/ in-vitro models for its effective utilization as therapeutic agent for the management of hypolipidemia. Keywords: Viburnum Cotinofolium Hyperlipidemia; Atorvastatin; Atherosclerosis

Mr AJAY KUMARImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : G.B PANT

UNIVERSITY OF AGRICULTURE AND

TECHNOLOGYDesignation : Ph.D Scholar

Mechanochemical synthesis (MCS) is advance frontier methodological techniques that promote thesynthetic efficiency of multi-compounds with economically effective yield. Ionic liquids alsosupport many reactions, but with difficulty to extract the catalyst from solution, that overcomewith magnetic nanocatalyst (MNC). In the present investigation, the synthesis of the Fe@Si-ILcatalyst supports the manufacture of sulphonyl organic compound (SOC) that has a property to act asan antidiabetic drug. Incorporation of MNC with ionic liquid (IL) increased the activity of IL andgives improved results. The magnetic ferrite nanoparticles (FNPs) were synthesized by treatingseveral concentrations of FeCl2.4H2O with ammonia solution at 80±1oC. FNPs were coated with SiO2followed by reaction with IL to develop Fe@Si-IL at 16 hr, 80±1oC. Synthesized Fe@Si-IL acts as acatalyst and works to enhance the rate of MCS. Organic IL presented in Fe@Si-IL with intramolecularionic charge, play a vital role in the synthesis of heterocyclic organic compound (HOC). The samereaction was monitored by different solvent conditions, moreover, effective output was obtained insolvent-free conditions, due to efficient catalysis at 72±1oC to obtain HOC. MNC-Fe@Si-IL could beextracted easily by using a magnetic separation method and can be used rapidly without loss catalystproperty. In the present work, SOC drugs were also developed the first time by the reaction of theHOC primary amine group with Tosyl-Cl. Synthesized catalyst Fe@Si-IL, FNPs, HOC and SOC were fullycharacterized via various analytical techniques. The present investigation provides an inexpensive,reduced organic solvent, high yield and green-friendly novel approach for the synthesis ofantidiabetic drug.

Dr MANJUNATHA CImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : R.V. College

of EngineeringDesignation : ASSISTANT

PROFESSOR

Developing a clean, renewable and green energy resource, alternative to very rapidly depletingtraditional fossil fuels is a matter of utmost urgency, for addressing challenges of the energycrisis, climate change and environment pollution. Recently, hydrogen (H2) has attracted extensiveattention as a clean and environmentally friendly energy source. Among metal chalcogenides, nickelsulfides such as NiS, NiS2, Ni3S4 etc have been attractive for both OER and HER owing to relativelyhigh conductivity. In this work we have demonstrated the elelctro-catalytic efficiency of nickelsulphide polymorphs for water splitting. Nickel sulfide polymorphs (NiS, Ni3S4, NiS2) were preparedby a one-pot hydrothermal process with different combinations of various experimental parameters.XRD patterns confirms three different polymorphs of nickel sulfides NiS, Ni3S4 and NiS2 wereobtained at 120°C, 150°C and 180°C respectively. The SEM images indicates the apple typemorphology for NiS, sugar cubes type microstrcure for Ni3S4 and tubular fibers type structure forNiS2, which are unique and has significant influence on elelctrochemical water splitting. The OERelectrocatalytic performance of NiS, NiS2 and Ni3S4 were measured in 0.1 M KOH with three-electrodesystem. It is observed from the linear Sweep Voltammetry (LSV) curves that the NiS exhibits anonset potential of 1.58 V, which is lowest onset potential compared to the bare electrode,commercial RuO2, NiS2 and Ni3S4. Further, the chronoamperimetricit profile exhibits the long termstability of the prepared nanostructured NiS. The OER electrocatalytic performance of nickelsulphide recorded in linear Sweep Voltammetry (LSV) curves confirms that the NiS exhibits an onsetpotential of 1.58 V, which is lowest onset potential as compared to other nickel sulfides.

Ms Archana VermaImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Bihar

Agricultural University, SabaurDesignation : Research

Scholar

Abstract: The use efficiency of nitrogen is generally low and it varies with cropping system and ecosystem. So, in intensive agriculture, nitrogenous fertilizers are added in large amount. Some part of this nitrogen remains unused and leached down beneath the soil layer which is called leaching. This nitrogen become a contaminant in streams and groundwater. Nitrate drained into the rivers, lakes and estuaries and contaminate the groundwater, which causes algal bloom, eutrophication and fish poisoning. Leaching of nitrate (NO3-) is great concern because it has a potential effect on water resources. Over-fertilization causes both leaching and decreased NUE. Even slight increase in dose of fertilizer can lead to this. As per World Health Organization (WHO) standards, more than 10 mg/L nitrate in groundwater is not good for drinking purpose but in some areas of many countries the level is increased beyond its critical limit. Due to intensive cropping, nitrogen level is get increased now-a-days than past few years, which lead to more contamination of groundwater in developed and developing countries. High nitrate in groundwater making it unfit for drinking and contamination due to this is taking place predominantly in agricultural areas. The quantity of residual nitrate content at harvest time should be reduced, even preservation and input of nitrate should also be redused during peak leaching period. So, the study of nitrate leaching has a great impact on managing and controlling pollution which has been derived due to intensive agriculture across the world. Key worlds: NUE, intensive agriculture, leaching, WHO.

Mr ANIMESH KUNDUImage Delegate ID Theme Details


Research



Abstract: The global energy demand is increasing gradually. In our society, the main source of energy is the burning of fossil fuels which are responsible for environmental pollution and also their stocks on earth are limited. So, the replacement of conventional energy sources by an energy system that uses sustainable fuel and reduces CO2 emissions is among the most critical issues of today’s society.[1] In this context, the development of artificial photosystem which splits water into hydrogen and oxygen using sunlight would be one of the potential solutions of world's energy problem.[2] The key step in artificial photosynthesis is the water oxidation but it is complicated as it involves multiple protons and electrons transfer and formation of an oxygen–oxygen (O-O) bond. The high energy thermodynamics also make the oxidation step even more challenging.[1] So, the development of potential water oxidation catalyst (WOC) attracts researchers to pursue. In this work, we have designed and synthesized few ruthenium complexes and characterized them using various spectroscopic techniques. Catalytic water oxidation activities of these ruthenium complexes, using Ce(IV) as a sacrificial electron acceptor at pH 1.0, have been examined. We have performed electrochemical studies to identify species involving in the water oxidation reaction. Kinetic studies and detail mechanistic investigations have been carried out to understand the O-O bond formation pathway. We have investigated possible deactivation pathway of the catalyst to develop efficient artificial photosystem device.[3] References: 1. Kaerkaes, M. D.; Verho, O.; Johnston, E. V.; Aakermark, B. Chem. Rev. 2014, 114, 11863-12001. 2. Sala, X.; Maji, S.; Bofill, R.; Garcia-Anton, J.; Escriche, L.; Llobet, A. Acc. Chem. Res. 2014, 47, 504-516. 3. Kundu, A.; Khan, S.; Dey, S.; Dutta, C.; Anoop, A.; Mandal, S. Eur. J. Inorg. Chem. 2019, 2019 (2), 164-177

Dr KINKAR BISWASImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Raiganj


Professor

Abstract: Schiff base and its complexes have immense attention for the development of bio-inorganic chemistry, since it has been recognized that many of these complexes may serve as models for biologically important species. Herein we discussed about the synthesis, characterization and applications of various rhodamine B hydrazide based schiff bases. The hassle-free synthesis and the sensor properties of the schiff bases are noteworthy. The pyridine-carbaldehyde-rhodamine B hydrazide schiff base sensed Cu2+ ion preferentially whereas salicylaldehyde-rhodamine B hydrazide schiff base sensed Fe3+ ion and were observed by UV-Visible spectroscopy. The schiff base-metal ion has ability to sense the sulfide ion in solution. Hydrogen sulfide is present in air primarily as a result of natural emissions and most of the hydrogen sulfide present in raw waters is derived from natural sources and industrial processes. A number of foodstuffs and drinks may contain sulfides. However, estimation of exposure from food is complicated by the formation of sulfides in cooked foods. Reproductive toxicity, embryotoxicity, teratogenicity, mutagenicity and carcinogenicity have been found after ingestion of sulfide ions. Therefore the detection of trace level of sulfide ions is hard task indeed. Herein we report Rhodamine B hydrazide based schiff base, which is capable of sensing the metal ions first (Cu, Fe ions) by colourimetry. After the formation of metal complex with RhB hydrazide schiff base, the sulfide ions can be also detected by colourimetry. References: 1. Karakus, E.; Sayar, M.; Dartar, S.; Kaya, B. U.; Emrullaho?lu, Chem Commun. 2019, 55, 4937-4940.

Mr Rajesh KumarImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Kumaun

UniversityDesignation : PhD scholar

Adsorptive-removal of Zn2+ using iron-zirconium mixed oxides nanoparticles : A green approach Rajesh Kumar,*, Shah Raj Ali, Zenab Khan, Sadaf Ansari and Naved Haider.

Department of Chemistry, Kumaun University, Nainital 263002, Uttarakhand, India. *Corresponding author (Email: [email protected], Tel-+91-9458115534)

Abstract: Iron-zirconium mixed oxides nanoparticles (IZO-NPs) with 1:1 and 1:2 of Fe:Zr molar ratio have been synthesized using the co-precipitation method. The removal of zinc like other heavy metals is a critical challenge for environmental researchers due to their toxicity and carcinogenicity [1-5]. The synthesized nanoparticles were successfully applied for the adsorption of Zn2+ from their aqueous solution [6]. X-ray diffraction technique, TEM, SEM-EDX, BET surface area analysis, TGA, FT-IR spectroscopy and Zeta potential analysis have been employed for the characterization of IZO-NPs with 1:1 and 1:2 of Fe:Zr molar ratio. The batch adsorption experiments were used for the adsorption of Zn2+ on synthesized nanoparticles. Isothermal studies show that the adsorption data were found to follow the Langmuir model better than the Freundlich and Temkin model. The results of reaction parameters showed that the adsorption was increased on increasing the pH and decreased on increasing temperature from 303 to 363K. The maximum adsorption capacity of IZO-NPs with 1:1 and 1:2 of Fe:Zr molar ratio was found to be 163.34 and 135.13 mg/g, respectively, under optimized conditions. The result of present study shows that IZO-NPs with 1:1of Fe:Zr molar ratio exhibit maximum adsorption potential than IZO-NPs with 1:2 of Fe:Zr molar ratio. The thermodynamic studies confirmed the involvement of weak Van der Waals forces between adsorbate and adsorbent and it proceeds spontaneously and exothermically. The result of kinetic study shows that, the adsorption of Zn2+ on IZO-NPs with 1:1 and 1:2 of Fe:Zr molar ratio followed a pseudo-second-order model satisfactorily. References: 1. Shi, Q.; Terracciano, A.; Zhao, Y.; Wei, C.; Christodoulatos, C.; Meng, X. Sci. Total Environ. 2019, 648,176-183. 2. Qu, J.; Song, T.; Liang, J.; Bai, X.; Li, Y.; Wei, Y.; Huang, S.; Dong, L.; Jin, Y.U. Ecotoxicol. Environ. Saf. 2019, 169, 722-729. 3. Barsbay, M.; Kavakli, P.A.; Tilki, S.; Kavakli, C.; Guven, O. Radiat. Phys. Chem. 2018, 142, 70-76. 4. Reddad, Z.; Gerente, C.; Andres, Y.; Le Cloirec, P. Environ. Sci Technol. 2002, 36, 2067–2073. 5. Fan, H. J.; Shu, H. Y.; Yang, H. S.; Chen, W. C. Sci. Total Environ. 2006, 361, 1–3. 6. Shahid, S.A.; Nafady, A.; Ullah, I.; Yun, H.; Yap, T.; Shakir, I.; Anwar, F.; Rashid, U. J. Nanomater. 2013, 2013, 1-6.

Ms Gita SinghImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Sunandan Divatia School of ScienceDesignation : Research

Scholar

Modelling and fabrication of high power and energy-dense electrochemical energy storage system are of great significance. Supercapacitor is one among them which is regarded as a promising avenue to bridge the gap between the conventional capacitors and rechargeable batteries. Herein, we have synthesized a new low-cost copper-doped manganese ferrite nanoparticle featuring high surface area and good conductivity for use as functional materials for storing and producing energy. Additionally, we developed a symmetrical supercapacitor system which is the fusion of conducting polymer and mixed metal ferrite to achieve high capacitance to 478 mAh/g at 1 A/g current density with excellent cycling stability of 5000 cycles. Morphology and structural analysis were carried out using Transmission electron microscope, Field-emission scanning electron microscope, Fourier transform infrared spectroscopy, X-ray diffraction, RAMAN and X-ray photoelectron microscopy (XPS) in detail. RAMAN and XPS were studied to investigate the detailed interactive mechanism between the CuxMn(1-x)Fe2O4 and PANI in the CuxMn(1-x)Fe2O4@PANI hybrid electrode material. The proposed energy storage system has been constructed without using any binder which simplified the electrode fabrication process by preventing the contact resistance between the electrode and current collector. We have developed a novel CuxMn(1-x)Fe2O4@PANI through a well-designed greener process via. in-situ chemical oxidative polymerization method. Additionally, a likely interaction mechanism of CuxMn(1-x)Fe2O4@PANI electrode material was examined using Raman and X-ray photoelectron spectroscopy. The CuxMn(1-x)Fe2O4 nano-ferrite showed high stability as an electrode material. Furthermore, a two-electrode system symmetrical supercapacitor swagelok cell was fabricated based on CuxMn(1-x)Fe2O4@PANI electrode without using any binder which gave superior electrochemical performances with a high specific capacitance value of 478 mAh/g and a high power density of 386 Wkg-1. Moreover, the fabricated symmetrical device based on the nanohybrid serves as a stable electrode material for high-rate energy storage devices like batteries and supercapacitors.

Mr KARNAN MANICKAVASAKAMImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : CENTRAL

ELECTRO CHEMICAL RESEARCH INSTITUTEDesignation : CSIR-SRF

Supercapacitors (SCs) are a promising energy storage device in the zone of energy stockpilinggadgets. In the last few decades, various kinds of carbon-based materials with reasonable surfacealterations, metal oxides, metal hydroxides, conducting polymers, and their different compositeshave been utilized as electrodes to improve the energy density of SCs. Nevertheless, evolving astorage device with optimal energy and power density is highly essential for practical use. Inrecent years, increasing attention move towards supercapacitors due to high power density, fastcharge/discharge rate, and extended cycling stability. Among the various carbon materials, theactivated carbon based electrode materials synthesized from bio waste are quite smart due to itslong cycle life, high specific surface area, low cost, availability, good electrical conductivityand chemical stability in electrochemical environments. However, preparing a high surface areacarbon with desired pore size and conductivity is still a challenging issue. On the other hand, thesupercapacitors cell voltage could be enhanced using redox additive electrolytes. Also, devicefabrication with various electrode configurations like asymmetric and hybrid systems are introduced.Strikingly, another elective methodology has been proposed of late by a few research groups, whereinthe electrolytes can improve the execution of the SCs through redox processes at theelectrode-electrolyte interface. Herein, a high energy supercapacitor is demonstrated usingactivated high surface area carbon derived from bio-source and redox additive electrolytes. Based onour observation and results, the Hydroquinone based redox additive showed a very high specificcapacitance of 895 F/g at 3 A/g and 525 F/g at 1 A/g in three and two electrode system,respectively. The detailed preparation of bio-mass derived carbon, materials characterization,electrochemical characteristics and supercapcitor performance of the bio-derived carbon will bediscussed in detail.

Ms Akansha DixitImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Defence

Materials and Stores Research and Development

EstablishmentDesignation : Ex-SRF

(DRDO)

Hydrogels are well-known soft materials that are used to develop soft and wet technology. The phenomenon of sudden and reversible volume changes in hydrogel materials under the influence of external stimuli such as temperature, pressure, electric and magnetic field, light intensity, pH and ionic strength of the medium, and chemical triggers are well-known. Such materials are called smart hydrogels (also intelligent hydrogels). On the other hand, self-healing hydrogels can autonomically repair any damage generated on them. A variety of judicially synthesized hydrogels may do this, and others may need an external stimulus to exhibit healing such as light, temperature, pH etc. The reversible bond breaking and bond making phenomenon prevents fracture of the molecular backbones in such materials. Self-healing materials are recent focus of materials research. On the other hand, synthesis of strong and stretchable hydrogels having self-healing and other functional properties is very much challenging to develop soft hydrogel materials for various applications. In a strategy of double network structures, we have established the synthesis of obtaining strong and stretchable hydrogels [3].

In this investigation, self-healable smart hydrogels were developed using judicial selection of various functional monomers and their combination forming double network (DN) hydrogels following their polymerization in presence of poly(vinyl alcohol) (PVA)-borax reversible complex network. Such DN hydrogel materials are new and unique hydrogel materials having self-healing properties. Such synthesized ionic DN hydrogels of PVA-borax and crosslinked P(AM-co-Na-AA) are highly swellable, highly stretchable and self-healable. The equilibrium degree of swelling was achieved as high as 6494 % (at pH=8.5) for an ionic DN hydrogel having acrylamide/sodium acrylate as 25/75. Such a DN hydrogel exhibited highest tensile strength of 1670 kPa and self-healing efficiency 69%. They may find potential applications as smart sensors, actuators and in biomedical field.

Mr ABHISHEK SAHAImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : IIT

GUWAHATIDesignation : STUDENT

Abstract: The protein nanoparticles (NPs) have good biocompatibility, biodegradability, and easy access for additional surface modifications. These NPs have been successfully used as drug delivery systems with increased bioavailability and reduced toxic side effects of the drug molecules. However, most of the effort shows poor hydrophobic drug encapsulation and delivery efficiency. Herein, we report a simple approach to formulating fatty-amine-conjugated cationic BSA (FCBSA) NPs by conjugating laurylamines to the BSA protein. Partial neutralization of the negatively charged glutamic acid or aspartic acid residues by the formation of an amide bond with laurylamines leads to the formation of cationic NPs under physiological conditions (isoelectric point = 7.7). The NPs exhibit high stability against thermal, pH, and proteolytic enzyme stresses. The protein NPs efficiently encapsulate hydrophobic anticancer drug doxorubicin (Dox) and have a controlled release property (?40% release after 3 days), human blood serum stability, antifouling properties, and a higher binding affinity for the anionic membranes. The biotin tagged cationic FCBSA (btFCBSA) also showed very similar biophysical properties to those of FCBSA. Furthermore, the cellular studies also showed that the NPs has excellent biocompatibility against both normal and cancer cell lines and bt-FCBSA can efficiently deliver Dox to the biotin receptor-positive HeLa cells, leading to significant cell death. An in vivo assessment of the Dox-encapsulated bt-FCBSA on Ehrlich ascites carcinoma cells on female Swiss albino mice revealed significant inhibition of tumor growth. Overall, easy access to the fatty-amine-modified cationic protein NPs with their surface modification capabilities could qualify them as candidates for both passive and active targeted delivery of anticancer agents.

References: 1. Saha, A.+; Pradhan, N.+; Chatterjee, S.; Singh, K. R.; Trivedi, V.; Bhattacharyya, A.; Manna. D.* ACS Appl. Nano Mater., 2019, 26, 3671-3683.

Mr vijay kumar juyalImage Delegate ID Theme Details

YSC 11402 Frontier areas of Research

Category : ChemistryOrganisation : G.B Pant

University of Agriculture and Technology


Hydrogel based magnetic materials display applications in cell separation, magnetic resonanceimaging and target-specific delivery of biomolecules. Drug loaded Magnetic nanoparticle's vehicle issurface-functionalized to deliver the drug at the final target destination without any hazardouseffect. Hydrogel coated ferrites impart magnetic field regulated thermo-sensitive characteristicsthat make them suitable for target delivery of biomolecules. In the present investigation, synthesisof green nanocapsules of ferrites hydrogels (FHGs) is derived from the polymer of (N-isopropylacrylamide) (NIPAM) that was conducted in a glass reactor with requisite quantity (mol/dL) ofmonomer. The process involves 2,2’-azobisisobutyronitrile (AIBN) originated in situ polymerizationof NIPAM monomers in presence of ferrites nanoparticle’s (FNPs) and bis-acrylamide (BAM)cross-linker at 90±1oC with 1200psi over 6 hr. Magnetic behavior of FNPs and respective FHGs werefound super-paramagnetic and the average crystalline size of FNPs about 19.5 nm. Poly-(N-isopropylacrylamide) (PNIPAM) characterized and investigated for the release of an anticancerous drugDoxorubicin (DOX). AIBN initiated polymerization of NIPAM in presence of BAM has afforded PNIPAMwith a pair of absorptions at 227 (weak) 245 (strong) nm. Such a blue shift in the absorption ofPNIPAM over monomer may be assigned to the loss of the unsaturation of the vinyl functionality as aresult of the polymerization reaction. Polymerization of NIPAM in presence of BAM and FNPs underidentical reaction conditions afforded FHGs with absorption at 227 nm. Such blue shift assignedbonding of amine functionality of the PNIPAM with FNPs. Ultra-violet spectrum reveals that FHGsdisplay in- vitro biocompatibility and sustained delivery of DOX up to 72 hrs at pH 7.2±0.2 and25±1oC. DOX was covalently attached to FHGs through an amide linkage. The present investigationprovides an inexpensive and green friendly method of FHGs suitable for target-specific delivery ofanticancer drugs.

Mr JAYANTA MONDALImage Delegate ID Theme Details


Research



Multicolor fluorescent carbon dots (MFCDs) have been attracted towards researchers due to theirexcellent properties, such as highly fluorescent in nature, low toxicity, chemical inertness, watersolubility, easy functionalization, and excellent biocompatibility. As a result, MFCDs findpromising applications in the fields of optoelectronic devices, optical sensing, catalysts, energy,in vivo, and biological analysis. Moreover, highly fluorescent CDs have been synthesis usingnontoxic, ecofriendly, biocompatible, and green source juice (such as banana, orange, apple, etc) toavoid chemical hazards and their higher carbohydrate contents. In addition, hydrogels have also beenreceiving great attention due to variety of applications, such as drug delivery, biomedical, tissueengineering, in vitro, and related to in vivo. Recently, fluorescent CD hybrid hydrogel have beenfabricated by using as external gelling agents, such as methyltriethoxysilane, agarose,triethylammonium salt, alginate, ionic liquids in CDs matrix and applied in detection of bacteriaand in the sensing of different metal ions. In view of these, fabrication of multicolor carbon dothydrogel (CD hydrogel) from juice (green source) has been a challenging task in the absence of anygelling agent. Motivated these, we fabricated a lowcost and ecofriendly multicolor CD hydrogel inthe absence of any gelling agent from a pear juice as a green precursor. Fabricated gel exhibitedmulticolor emission excitation dependent red shifted due to the presence of characteristichydrophilic surface in CDs. Further, CD hydrogel formation mechanism has been discussed.Interestingly, our study showed the detection of carbon materials using fabricated CDs hydrogel.Further, we also investigated the optical interaction between them as a feature of the application.It may be concluded that the interaction is mainly guided by the electron rich CDs and electronacceptance ability of carbon materials. Further, such interaction could be beneficial for thefabrication of optoelectronics, photovoltaic devices, and sensing of biomolecules.

Dr Pradip Kr SukulImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Amity


Professor

Water contamination is currently one of the world’s leading causes of death with an estimated 1billion people without access to clean drinking water and 2 million casualties per year.1 The watercrisis is only expected to worsen as the World Health Organization (WHO) estimates that climatechange will limit access to clean water for as much as half of the world’s population,2 and arecent United Nations report projects that the world could face a 40% water shortage in as few as 15years.3 An exponential increase in heavy metal use in industrial processes for energy productionhave caused a surge in human exposure to toxic heavy metals in recent decades.4 The heavy metalsplay no role in human homeostasis, induce multiple organ damage, cause birth defects, and areclassified carcinogens.4 With the rapid growth of industrialization and urbanization, Pb2+ dischargehas become a serious environmental concern.5 Several countries concentrated to remove Pb2+ frompotable water in order to reduce levels of elevated blood Pb2+ in children. Owing to the fact, theremoval of Pb2+ from water is critical in terms of protection of public health and environment. Manyefforts have been dedicated to purify wastewater to get more available clean water. Here, we reportinexpensive superparamagnetic nano particles made from L-DOPA functionalized perylene diimide thatcan be used to remove lead (II) ions from water. The characterization of the nano particle wassubstantiated by X-Ray diffraction study, scanning electron microscopy, high-resolution transmissionelectron microscopy. All the materials (PDI, Fe3O4) are cost-friendly, nontoxic, easily synthesizedwith an outstanding adsorbing capacity of 1407.5 mg g-1 & Kd value of 1.14 x 106 mL g-1. The amazingdoughnut-shaped duo of PDI & Fe3O4 nanoparticle will make a significant contribution to heavy metallead purification methods from water.

Dr Shah Raj AliImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Kumaun

University, NainitalDesignation : Associate

Professor

Synthesis of copper hexacyanoferrate nanostructures and subsequent application in voltammetric sensing of paracetamol

Shah Raj Ali* Department of Chemistry, D.S.B. Campus, Kumaun University, Nainital 263 002, Uttarakhand, India. Email: [email protected], +91-9286900994

Abstract: High ionic conductivity and excellent redox mediator characteristics of metal hexacyanoferrates open new frontier for development of voltammetric sensors for a variety of molecules of environmental, biomedical and pharmaceutical interest. The present work deals with the synthesis of copper hexacyanoferrate nanostructures and subsequent application in voltammetric sensing of paracetamol. Copper hexacyanoferrate nanostructures have been synthesized through an extremely simple rout and characterized in terms of elemental analysis, thermal studies, infrared spectroscopic and X-ray diffraction techniques. Field emission scanning electron microscopic image indicated that it consisted of irregular spherical particles with size ranging from 40 to 90 nm. Copper hexacyanoferrate nanoparticle-carbon nanotube composite material was prepared following the reported method and employed to modify the glassy carbon electrode. The modified electrode was found to reduce the peak potential of paracetamol nearly 65 mV. It showed a linear response over a wide concentration of paracetamol. The values of correlation coefficient, sensitivity and detection limit were determined. The results of present study reveal that the modified electrode can be used as a biosensor for paracetamol drug.

References:

1. Balmaseda, J.; Reguera, E.; Gómez, A.; Díaz, B.; Autie, M. Microporous Mesoporous Mater. 2002, 54, 285-292.

2. Avila, M.; Reguera, L.; Rodríguez-Hernández, J.; Balmaseda, J.; Reguera, E. J. Solid State Chem. 2008, 181, 2899-2907.

3. Rodríguez-Hernández, J.; Reguera, E.; Lima, E.; Balmaseda, J.; Martínez-García, R.; Yee-Madeira, H. J. Phys. Chem. Solids 2007, 68, 1630-1642.

Dr MANIKANDAN DImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : DR.

Mahalingam College of Engineering and Technology,

Pollachi Designation : Assistant

professor

Abstract: Aegle marmelos commonly known as bael belongs to the Rutaceae family. It has been broadly used in indigenous systems of medicine due to its tremendous therapeutic properties. Besides its wide medicinal therapeutic values, bael gum (BG) extracted from this fruit shows anti-cancerous and photo thermal activity .Extensive research has shown that bael extracts are effective in inhibiting the growth of leukemic K562, B-lymphoid erythroleukemic HEL, melanoma Colo38, breast cancer cell lines MCF-7 and lung cancer A-549 cell lines. Drug delivery systems based on nanoparticles have proved to be a great route for targeting brain tumors where the conventional therapy is not effective. Enhanced permeability and retention (EPR) is the unique property of nanoparticles to accumulate and interact with the tumor cells. Gold nanoparticles (Au NPs) are suitable for thermal destruction of cancer cells due to the ease with which they can be surface functionalized enabling penetration into cells and the ease of excitation with NIR that is required in Photothermal therapy. Au NPs are attracting enormous attention in applications for immunoassay, drug delivery, contrast enhancement and thermal therapy for tumor treatment due to their nanoscale size, oxide free components, bioconjugation property, biocompatibility, and unique optical properties. Triangle shaped gold nanoparticles absorb NIR radiation, which is a prerequisite for Photothermal activity and thus can also serve as a suitable drug carrier. To be specific, triangular Nanoplates (NPs) of gold with anisotropic electrical conductivity are promising in diverse applications of therapeutics. Imperatorin, a furanocoumarin derivative is distributed mainly among plants from the Apiaceae and Rutaceae families Its pharmacological properties are well documented, which make it a candidate for possible drug development. It also has shown an antiproliferative effect on several cancer cell lines. This study aims to isolate Imperatorin from bael gum through column chromatography using ethyl acetate in hexane as eluent for the purpose of preparing triangular gold Nanoplates with surface-functionalized C. These particles in turn shall be used to investigate biological activity on various cancerous cell lines, invitro. More specifically, Photothermal and anticancer activity in A549 lung cancer cell lines shall be examined under optimized conditions. Keywords: Imperatorin, Triangular Gold Nanoplates, Photothermal therapy

Mr Basudeb DuttaImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Aliah

UniversityDesignation : Senior

Research Fellow

Abstract: In the present scenario solid-state reactions involving structural revolutions receive considerable attention among the scientists working in the field of coordination compounds because of the green synthetic route and single crystal to single crystal (SC to SC) transformation. This is actually the involvement of a solvent-free simple synthetic technique and the development of product that may otherwise be difficult to obtain by a predictable route. Among solid-state reactions, photochemical [2+2] photodimerization, by which a stereoseletive cyclobutane ring is formed in photoactive organic as well as coordination compounds, is mostly fascinating. Keeping in mind the above concept a metal–organic compound [Cd(quin)2(4-nvp)2] [1; Hquin = quinoline-2-carboxylic acid and 4-nvp = 4-(1-naphthylvinyl)pyridine] was synthesized and structurally characterized via Single X-ray crystallography. Maintaining topochemical principal the compound undergoes [2 + 2] cycloaddition by sunlight irradiation to generate a one-dimensional coordination polymer. Interestingly this reaction is thermally reversible, and switching between two crystalline forms can be monitored by conductivity measurements.1 As the compounds are electrically conductive, thus they can be employed for the fabrication of electronic device; which is very much important in this energy crisis civilization.

Reference: 1. B. Dutta, A. Dey, C. Sinha, P. P. Ray and M. H. Mir, Inorg. Chem. 2019, 58, 5419 – 5422.

Dr BIMAN KUMAR PATELImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : JADAVPUR

UNIVERSITYDesignation : RESEARCHER

Curious Results in the Prospective Binding Interactions of the Food Additive Tartrazine with ?-Lactoglobulin Biman Kumar Patel* and Ambikesh Mahapatra Department of Chemistry, Jadavpur University, Kolkata 700 032, India *E-mail: [email protected] Abstract ?-Lactoglobulin (?-LG) is a very well familiar food supplement found in bovine milk. Tartrazine (TZ) is a very common food additive dye. A large number of milk products (cookies, ice creams, pastries, cake, sweets and snacks) with TZ are widely prepared in food industries. ?-LG (?-sheeted protein) has a natural tendency to form amyloid fibril by self-aggregation like A? protein. Nowadays millions of people in the worldwide suffer from amyloid diseases. Fibrillations are associated with various types of chronic diseases such as Huntington’s, Alzheimer’s, Parkinson’s, prion disease, type-2 diabetes, etc. A detailed characterization of the binding interactions between food additive TZ and ?-LG have been investigated through spectroscopic techniques along with theoretical studies. Spectroscopic measurements reveal that quenching mechanism of ?-LG is mainly static in nature. The molecule specifically bound to a single binding site of the protein with a stoichiometric ratio of 1:1 and the observed binding constants (104, K) are 7.64, 9.13, 9.72 and 10.79 at 293, 298, 303 and 308 K respectively. However, in the case of static quenching, the curious results of binding constants (K) with temperature have been well explained on the basis of Le-Chatelier’s principle. Thermodynamic data, pH dependent studies along with surface hydrophobicity binding displacement assay reveals that the binding phenomenon is mainly entropy driven process suggesting noteworthy interactions of such ionic molecules with the hydrophobic part of the protein. The modulation of protein conformation has been investigated by spectroscopic and dynamic light scattering (DLS) studies. TZ had a significant inhibitory effect on protein fibrillogenesis. Furthermore, theoretical study gives accurate insights about the binding of TZ with ?-LG in compliance with the experimental findings. This study would be helpful towards pharmaceutical, food and industrial engineering chemistry research. References: 1. Patel, B. K.; Sepay, N.; Mahapatra, A. Langmuir 2019, 35, 11579?11589.

Dr Pawan Kumar MauryaImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : ICMR-

Regional Occupational Health Centre (Eastern)

Designation : Scientist-B

A simple, paper-based analytical method was developed for the quantitative, visual, and sensitiveanalysis of lead ions in a drinking water with a sensitive detection limit of 15ppb, which is inaccordance with the EPA limit of lead in drinking water. The method is based on classic ring oventechnique developed by H. Weisz. The proposed preconcentration technique is based on the dropwisedelivery of a small volume of sample to a filter paper, assisted by a flow-injection-like system.The filter paper is maintained in a small circular heated oven (the ring oven). Drops of the samplesolution diffuse by capillarity from the center to a circular area of the paper substrate. After thetotal sample volume has been delivered, a ring with a sharp circular contour formed on the paper tocontain most of the analytes originally present in the sample volume. The amount of lead present inthe ring is further allowed to react with potassium chromate to develop yellow color. Furthermore, asmartphone was used in the visual detection of lead ions by identifying the RGB value of the ring.The application of smartphones and ring oven technique has greatly shortened the detection time andreduced the cost. The technique is very useful to measure quality of water as well as a trainingtool for students in chemistry laboratory since it don’t implies sophisticated techniques likeAAS, ICPMS. Laser Induced Breakdown Spectroscopy etc.

Dr Ashoka SImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : ayananda

Sagar UniversityDesignation : Assistant

Professor

The search of new multifunctional cathode materials, with new crystal structures and compositions, for lithium ion battery is extremely important to mitigate the drawbacks associated with the current electrode materials used in the rechargeable lithium ion batteries. In this work, othovanadate family CrVO 4 has been identified and investigated as a new cathode material for high rate and high capacity lithium ion battery for the first time. A solution based effective and versatile synthetic protocol has been proposed to synthesize CrVO4 nanoparticles. Physical characterizations reveal that the prepared CrVO 4 consists of uniform and discreet nanoparticles of crystallite size ?19 nm with widespread pore diameter, enhanced conductivity and surface area. The prepared CrVO 4 nanoparticles have been evaluated as a potential cathode material for lithium ion batteries, wherein the experimental results demonstrate enhanced lithium storage with high rate capability and cyclability.

Mr Mehebub Ali KhanImage Delegate ID Theme Details


Research



Scholar

Abstract: An asymmetric hydrazide (7-(diethylamino)-3-((E)-((E)-((2-hydroxynaphthalen-1-yl)methylene hydrazono) methyl)-2H-chromen-2-one) (1) has been synthesized and characterised by NMR, IRand X-ray crystallographic analysis. The compound 1 has been found to show solvent dependentabsorption as well as emission properties. The photophysical properties of the compound 1 have beeninvestigated using UV-Vis spectral study, steady state emission study as well as time dependentemission experiment. The photophysical properties of compound 1 have been justified by theoreticalcalculations. Local environment sensitive emission property of the molecule has been exploited forthe detection of aromatic nitro-compounds. Compound 1 can detect aromatic nitro-compounds in theiraqueous solution with very high sensitivity. The sensing mechanism has been explained on the basisof fluorescence quenching which has been established by means of spectroscopic investigations.

Mr ISMAIL SKImage Delegate ID Theme Details


Research



Scholar

Abstract: The synthesis of silver nanoparticles from aqueous extract of Ipomoea batatas. Thesynthesized nanoparticles particles have been characterized using UV-visible spectroscopy, X-raydiffraction analysis, Fourier transform infrared spectroscopy and Transmission Electron Microscopy.It could be utilized for selective colorimetric detection of potentially health and environmentallyhazardous Hg2+ metal ions in aqueous solution. It has been also found that the silver nanoparticlesshow reversible response towards Hg2+ ion and catalysts activity towards aromatic nitro groups.

Ms Latika NegiImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : DSB Campus,

Nainital Designation : Research

Scholar

The study consisted of the determination of some physiochemical properties in drinking water samplesfrom the Kosi River Ramnagar. Kosi River is the major river system of Uttarakhand and UttarPradesh. The Kosi River performs a basic part in local society for drinking and irrigation purpose. A water quality indicator (WQI) calculated from nine physiochemical parameters, periodicallyevaluated at separate sampling locations (july2017 to aug2018) to characterize the spatial andtemporal variation of surface water performance in the watershed. The results showed moderate waterquality in the upper and middle areas. Downstream of Ramnagar City, water quality circumstances werecritical because of the impacts of the release of residential wastewater.

Dr Santanab GiriImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Haldia Institute of Technology


The chemistry of boron compounds usually exhibits Lewis acidity at the boron centers, due to thepresence of its vacant p-orbitals. We show that this chemistry can be altered by appropriate choiceof ligands, decorating the boron center. To elucidate this effect, we studied the interaction ofboron with two classes of ligands, one based on penta-substituted phenyl species (C6X5, X = F, BO,CN) and the other on Zintl-ion based groups (Ge9Y3., Y = H, CH3, BO, CN). An in-depth analysis ofcharge and Fukui function values at the local atomic sites of substituted boron derivatives,[B(C6X5)3] and B[Ge9Y3]3, shows that the B-center in the former is electrophilic, while it isnucleophilic in the latter. The chemical stability of the B[Ge9Y3]3 species is shown to be due tothe presence of strong 2c – 2e bonds between the B and Ge centers. Thus, the usual notion of theLewis acid nature of a boron center depends upon the choice of the ligands.

Dr Abhijeet KumarImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Mahatma Gandhi Central UniversityDesignation : Assistant

Professor

In developing counties like India and others, health is a subject of foremost concern. Despite ofseveral excellent initiatives such as Ayushman Bharat Yojna taken by the present government, thehigh cost of medicine is the major challenges to be addressed in case of fatal disease like cancer.Heterocyclic rings are prevalent as core scaffolds in several bio-active compounds and drugs. It isestimated that more than 85% of commercially available drugs which are being prescribed to treat avast range of diseases and physiological disorders are known to contain heterocyclic motifs in theircore scaffolds. Flavonoids including neoflavones, flavones, isoflavones are naturally occurringphytochemicals with a vast range of pharmacological activities such as anti-inflammatory,anti-cancerous, anti-viral etc. Similarly, N-heterocycles such as pyrazoles and pyrimidines areheterocycles of immense biological importance.1 In particular, diarylpyrazoles and pyrimidines areknown to display a vast range of pharmacological activities such as anti-tumor, anti-inflammatory,anti-depressant etc. for the synthesis of 3,4-diarylpyrazoles and 4,5-diaryl-2-aminopyrimidinesthrough isoflavones. Although various synthetic methods have been reported previously, the presentmethod involves the use of triarylbismuths as threefold coupling reagent. The advantage of usingthis reagent lies in the fact that it leads to the formation of 3 equivalent of arylated compoundusing one equivalent of the bismuth. The work presented here would be describing about thedevelopment of efficient Pd-catalyzed protocol for the synthesis of flavonoids via cross-couplingsof 4- Chlorocoumarin, 3-trifloxychromones with triarylbismuths as threefold coupling reagent insub-stoichiometric amount. Similarly diarylpyrazoles and pyrimidines were also prepared inpot-economic fashion. The methods allowed the rapid access of a library of synthetic analogues ofphytochemicals under palladium-catalyzed conditions. The arylpyrazoles have also exhibitedanti-cancerous properties which indicate that these bio-actives molecules could further be developedas anti-cancerous drugs.

Mr Azhar IqbalImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : JAMIA

HAMDARDDesignation : scholar

Abstract: A series of imidazopyridine-thiazolidinone hybrid4-(3H-imidazo[4,5-b]pyridin-2-yl)-4-oxo-N-(4-oxo-2-substituted phenylthiazolidin-3-yl)butanamidederivatives and another series of imidazopyridine-methyl thiazolidinone hybrid were synthesized and investigated of their anticancer activity.(E)-N'-benzylidene-4-(3H-imidazo[4,5-b]pyridin-2-yl)-4-oxobutanehydrazide were reacted withthioglycolic acid to give 4-(3H-imidazo[4,5-b]pyridin-2-yl)-4-oxo-N-(4-oxo-2-substitutedphenylthiazolidin-3-yl)butanamide derivatives whereas(E)-N'-benzylidene-4-(3H-imidazo[4,5-b]pyridin-2-yl)-4-oxobutanehydrazide were reacted withthiolactic acid to give4-(3H-imidazo[4,5-b]pyridin-2-yl)-4-oxo-N-(4-oxo-2-phenylthiazolidin-3-yl)butanamide derivatives.The structure elucidation of the newly synthesised compounds was performed by IR, 1H-NMR, massspectroscopic data and elemental analyses. All the compounds were evaluated for anticancer activityagainst a panel of four human cancer cell lines. The hybrid AI5a and AIe6 showed best anticancerresult against HepG2 human liver cancer cell line with IC50 value 20 nM and 160 nM compare tostandard drug Doxorubicin with IC50 value 620 nM. The docking study of these two series have beenperformed and found that the Hybrid AI5a and AIe6 have highest docking score among all which is alsosupport the anticancer results of both hybrids AI5a and AIe6. Further, the tested compounds showedanti-inflammatory activity ranging from 26.54 to 82.23% and the standard drug Celecoxib showed78.34% inhibition after 3 hours. The compounds AI5a and AIe6 showed the maximum inhibition (82.23%and 81.77%).

Dr SUMIT KUMARImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Central University of Haryana,

MahendergarhDesignation : Assistant

Professor

A diverse range of novel and highly functionalized flavonoids based tanaproget hybrids weresynthesized and evaluated in vitro for their antimicrobial and anti-proliferative activities. Novelproducts were synthesized in good yields (81-95%) under Pd-catalysed reaction from bromo flavonesand tanaproget boronic acids within 18-20 min at 60 0C. Bioassay results exhibited excellentactivities against both hormone-dependent and hormone-independent human breast cancer cells (MCF-7,MDA-MB-231, DU-145, PC-3 and HeLa). Among them, compounds 4e, 9a, 9c, 9e, 9g, 9h, 9m and 9ndisplayed excellent activity. Compounds 4d, 4o and 9o were found equally potent against C. albicanscompared to fluconazole. Compound 5c showed better antibacterial activity against S. aureus.Compounds 5a, 9i, 9o and 10c have shown admirable antibacterial activity against E.coli.

Mr GOURHARI JANAImage Delegate ID Theme Details


Research


KharagpurDesignation : Research Scholar(5th year ph.d.)

Compounds having M-Ng-C and C-Ng-N bonding units are reported and the stability and nature of bonding in MNgCN (Ng = Xe, Rn)1 and NCNgNSi (Ng = Kr-Rn)2 family are analyzed by employing both density functional theory (DFT) and ab initio computations. The thermochemical stability of the Ng insertion compounds is evaluated by considering various possible dissociation channels. The metastable behavior of MNgCN and NCNgNSi compounds is reflected in the endergonic nature of all the dissociation channels but for one with respect to which they are kinetically protected. While the former compounds undergo the internal isomerization processes, MNgCN NgMCN and MNgCN NgMNC, which are then followed by a further dissociation to produce, free Ng and MCN or MNC. NgMNC can also convert to NgMCN but through a double step process in Cu cases and one step process for Ag and Au cases. A thorough inspection of the bonding situation of the studied molecules, employing natural bond order, electron density, adaptive natural density partitioning, and energy decomposition analyses indicates that the M–Ng bonds in MNgCN and Ng–C bonds in AuNgCN can be represented as an electron-shared covalent bond. For the other Ng–C bonds, although an ionic description is better suited, the degree of covalent character is also substantial therein. On the other hand, in case of NCNgNSi compounds both Ng-N and C-Ng bonds (except for the latter bond in compound containing Rn) are covalent in nature.

Mr Prasenjit DasImage Delegate ID Theme Details


Research

Category : ChemistryOrganisation : Indian Institute Of Technology

KharagpurDesignation : PhD Scholar

A Complex Containing Four Magnesium Atoms and Two Mg-Mg Bonds Behaving as an Electride Prasenjit Das,a Ranajit Saha,a Pratim Kumar Chattaraja,b,*

a Department of Chemistry and Center for Theoretical Studies, Indian Institute of Technology Kharagpur, Kharagpur 721302, India b Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, 400076, India E-mail: [email protected] (PKC)

Abstract: A new class of modified beta-diketeminate based Nacnac ligand1,2 ( L) was designed which holds two Mg(I)-Mg(I) bonds simultaneously. Density functional theory (DFT) based methods have been used for this study. The natural bond orbital (NBO) analysis indicates that the Mg atoms are in +1 oxidation state and two Mg(I)-Mg(I) covalent bonds in the designed complex [Mg4(L)2]2-. The atoms in molecule (AIM) analysis shows the presence of non-nuclear attractor (NNA)3 at the middle of each Mg(I)-Mg(I) bond. The Laplacian of electron density is negative at the NNAs and electron localization function (ELF) basins are present around the NNAs.3 The complex shows high non-linear optical (NLO)4 properties (average linear polarizability, second hyperpolarizability). So the designed complex satisfied all of the criteria and can be identified as an electride.3,4,5

References: 1. Green, S. P.; Jones, C.; Stasch, A. Science 2007, 318, 1754-1757. 2. Stasch, A.; Jones, C. Dalton Trans.2011, 40, 5659-5672. 3. Postils, V.; Garcia-Borràs, M.; Solà, M.; Luis, J. M.; Matito, E. Chem.Commun.2015, 51, 4865-4868. 4. Garcia-Borra?s, M.; Sola?, M.; Luis, J. M.; Kirtman, B. J. Chem. Theory Comput. 2012, 8, 2688-2697. 5. Dale, S. G.; Johnson, E. R. J. Phys. Chem. A 2018, 122, 9371-9391.

Mr Rituparno ChowdhuryImage Delegate ID Theme Details


Research


Institute of Science Education and Research KolkataDesignation : Student

Molecular Crystals come in all shapes and sizes, yet they are intriguing to us not only because of their striking organizational symmetry, but rather because of the emergent properties these symmetries give rise to. These properties manifest themselves in a big way, be it in the form of the counter-intuitive mechanical and photo-mechanical bending of molecular crystals despite being perfectly periodic and ordered, or the emergence of piezoelectric, triboelectric, ferroelectic and niche optical activity due to simplistic changes such as those in the space group of the lattice. The aim of my talk/poster is to present the recent advances we have made at the Flextal Lab@IISER Kolkata and CCB Lab@IISER Pune whose collaboration has led a conjoint effort in using cutting edge Quantum Mechanical, Hybrid Biased Molecular Dynamics and Scale-able simulations of hundreds of molecules at the 0.1-0.5 microsecond regime along with rigorous synthetic, analytical and physical experiments to rationalize, predict and design these amazing solids and understand at a depth never before seen in literature. In this talk/poster, we will be describing the Theoretical and Experimental investigations conducted and the philosophy behind them as such. We will also extend these to draw correlations between observed yet unexplained phenomena and finally we will extrapolate this to predict properties of known materials along experimentally inaccessible faces as well as eventually design materials using a hybrid statistical-mechanical and machine learning framework. This will in total, bring together people who are interested in a variety of fields to come and merge together in a single topical melting pot which is at the absolute frontiers of modern science.

Ms Harsha SonayeImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Taywade

College of pharmacy KO rad I nagpur


A knowledge of the CMC is very important when using surfactant. As the surface tension does notreduce further above the CMC in many processes the CMC specifies the limiting concentration formeaningful use. When the formation of micelles is desirable, e.g. when cleaning, the CMC is ameasure of the efficiency of a surfactant. The main objectives of this work the is to determine theCMC of an anionic and non ionic surfactant, with two different method Surface tension andConductivity method. CMC of anionic and non ionic surfactant with the organic electrolyte in theaqueous medium at room temperature from the conductometry and surface tension was determined. Thevalue so obtained show the decrease in CMC with the increase in electrolyte concentration andapproaches to a constant value. In the presence of the anionic surfactant & electrolyte lowering theCMC but decrease the surface tension of the surfactant.

Dr alka guptaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Sam

Higginbottom University of Agriculture Technology and

SciencesDesignation : Assistant

Professor

Better nutrition means stronger immune system, less illness, better health and productive community.In developing countries like India various forms of malnutrition affect a large segment ofpopulation and both macro and micronutrient deficiencies are of major concerns. In view of this thepresent study was conducted in Eastern districts of Uttar Pradesh, to assess the nutritional statusof 400 rural school going children (age 6-13 years). Nutritional status of children was assessed interms of dietary assessment, anthropometric measurement and clinical assessment of signs andsymptoms of various micronutrient deficiency diseases. Dietary assessment was done by 24 hourdietary recall method for three consecutive days. The results of the study revealed that food andnutrient intake was inadequate and anthropometric measurements (mean height and weight) were lowerthan reference value of ICMR. Hemoglobin test revealed that 67.25% had hemoglobin level below thenormal (12 g dl) values, indicating anemia, out of which approximately half (35.33%) weremild anemic and 32% were moderate anemic. On the basis of nutrition status data, among all surveyedschool going children 67.25% were suffering from anemia and 28% were suffering from Vitamin Adeficiency.The health and nutritional status of school children of Eastern district of Uttar Pradeshwas, on the whole very poor. The fact that several children still suffer from the worst form ofmalnutrition calls for immediate attention to be given to this group of children. Correction of thesituation of inadequate and poor quality diets is thus, imperative for the overall development ofchildren. There is an urgent need to promote the importance of balanced diet and preparation ofnutrient-rich recipes based on locally available food stuffs to improve their nutritional status.

Ms ANURADHA SINHAImage Delegate ID Theme Details


Research

Category : OthersOrganisation : BIHAR

AGRICULTURAL UNIVERSITYDesignation : student (Ph. D)

Tomato is most liked and versatile vegetable that is grown throughout the world. Tomato has a hugedemand in the local and national markets throughout the year but round the year production of tomatois not possible in open field conditions because it is highly sensitive to biotic and abioticstresses and as a result high quality, diseases and pests free production of tomato is not possibleas compared to tomato produced under protected condition. So the study was carried out with fourteengenotypes of tomato which were collected from different sources and planted at Polyhouse Complex,Department of Horticulture (Veg. & Flori.), BAU, Sabour during September 2018 to May 2019 to assessthe genetic variability and character association for yield and its attributing traits in tomatogenotypes for protected conditions. The experiment was laid out in randomized block design withthree replications. Data were recorded for sixteen morphological traits and five biochemical traits.The experimental results revealed that there were considerable differences among the genotypes forall the traits except titratable acidity and ?- carotene. Thus, there was abundant scope forselection of promising genotypes. Higher magnitude of phenotypic and genotypic coefficients ofvariation were observed for no. of flowers/truss, no. of locules/fruit, no. of fruits/truss, fruityield/plant, no. of fruits/plant, average weight of fruit, final plant height, titratable acidity,lycopene, ascorbic acid and ?-carotene. High heritability together with high genetic advance as % ofmean was observed for all traits except days to fruit picking which indicated strong influence ofadditive gene action. Based upon correlation and path coefficient analysis characters like no. offlowers /truss, equatorial diameter, pericarp thickness and no. of fruits /plant could be reliableselection parameters for evolving high yielding genotypes.

Ms Suchitra MishraImage Delegate ID Theme Details


Research

Category : OthersOrganisation : UDPS,

RTMNUDesignation : Ph. D.

Research Scholar

Abstract: Rizatriptan Benzoate is a selective agonist of serotonin (5- hydroxytryptamine; 5-HT) type 1B and 1D receptors. It is structurally and pharmacologically related to other selective 5-HT1B/1D receptor agonists and has only a weak affinity for 5-HT1A, 5-HT5A, and 5-HT7 receptors. It has poor bioavailability due to hepatic first-pass metabolism (Oral Bioavailability 45%). The present investigation aimed to prepare a nanoparticulate drug delivery system of Rizatriptan Benzoate using poly(lactic-co-glycolic acid) (PLGA) for direct nose-to-brain delivery to provide brain targeting and sustained release. PLGA nanoparticles (NP) were prepared by the nanoprecipitation technique and characterized by entrapment efficiency, particle size, zeta potential, differential scanning calorimetry (DSC) and X-ray diffraction (XRD) studies. The NP were evaluated for in-vitro release, ex-vivo diffusion, toxicity and pharmacokinetic studies. The optimized NP formulation is 161.1 ± 5 nm in diameter and had entrapment efficiency 79.53 ± 2 %. DSC studies indicated no broadening of the drug peak and no shift in the polymer peak, hence no physical interaction has been seen. DSC studies indicated absence of the drug peak which confirmed molecularly dispersed drug in PLGA matrix. XRD studies indicated a decrease in the crystallinity of Rizatriptan Benzoate or amorphization. In vitro drug release showed a sustained release, following the Fickian diffusion-based release mechanism. Ex vivo diffusion through goat nasal mucosa showed 67.51±2.60% of drug diffusion in 210 min from NP. Histopathological study of goat nasal mucosa showed no significant adverse effect of Rizatriptan Benzoateloaded PLGA NP. These results proved that Rizatriptan Benzoate could be transported directly to the brain after intranasal delivery of PLGA NP, enhanced drug concentration in the brain and would therefore be effective in improving the treatment of migraine. Keywords: Brain targeting, Rizatriptan, PLGA, in-vitro, ex-vivo. References: 1. Parvathi M. et al, Intranasal drug delivery to brain: An overview. Int. J. research in pharm. & chem. IJRPC, 2012, 2231-2781.

Mr Prakhar SahuImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Amity University, Lucknow


The industrial revolution, also called Industry 4.0 (I4.0), needs technicians, academicians,scientists, researchers and workers with abilities and competences in the Key Enabling Technologies(KET): Big Data, Cloud Computing, Internet of Things, Augmented Reality, Simulation and modelling,etc. Industry 4.0 is the fourth phase of the industrial revolution and aims to connect industriesand enterprise to the internet using KET to get better outcomes for future trends. The previousthree phases were introduced in the year 1765, 1870 and 1969 respectively to introduce initialtechnical advancements in various fields. Since Industry 4.0 is a data-driven revolution, it'stotally dependent upon sensors and cloud services to evaluate requirements and to gather informationfrom end-users. This phase of the industrial revolution is now being adopted by many companies andit's now one of the trending and emerging topics of today. Every change has its goods and bad but ifit's about survival, it becomes a threat. With rapid adoption of this revolution, intellectuals inevery domain have seen drastic surge in the employment rate, however we are not here to talk aboutemployment but something more dangerous than that, the privacy and its security. In the world wherewe all are connected through the internet exchanging data from one point to another, privacy andsecurity of user data become one of the major concern because it’s like a “fuel” to theinternet. These practices will become more common in 2020s and later as more devices will beconnected by then and predictions states internet of things will have more than half of the sharesin that. The data gathered by these connected devices is quite useful for companies to evaluatetheir needs without letting users know. If someone gets access to this data, it might cause aserious damage to the users or the company itself. This paper not only evaluates the spaces whereIndustry 4.0 may be less effective but also lightens the possible loopholes and suggests efficientsolutions to be implemented for Industry 4.0. Some bridges are also proposed in this work to bringacademia closer the industry, exploring some new academic strategies and proposing new roles to beclose to I4.0.

Mr Dinesh SinghImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-NPL

Designation : Sr. Technical Officer

HRTEM has become an indispensable tool for material science research and development due to its capability to resolve atomic positions within materials. It has helped in resolving and understanding many material science issues e.g. the phenomenon occurring at the interfaces, within the grains, at the grain boundary, presence of defects etc, which would not have been possible otherwise. In order to have good quality and interpretable image in transmission electron microscope (TEM), sample preparation play crucial role. TEM specimen must be electron transparent [1] and representative of the material one wants to study. It should be uniformly thinned and should be stable under electron beam. It should be conducting and non magnetic. In general, we can divide the specimen into two groups: self supported specimens and specimen resting on a support grid of Cu, Ni etc. Specimen resting on a support grid doesn’t need much explanation but uniformly dispersion is required in this case. Self supported grid is prepared for samples like bulk material, thin film samples etc.

Prof sanchita ghoshImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Innovative

college of pharmacy, greater noida, U.P


Butea monosperma (Lam.) Taub.; O. Kuntze family-Papilionaceae is commonly known as “palash”, in Hindi, and distributed throughout the greater part of India. Its bark is prescribed to cure night blindness and elephantiasis, and its seeds are used as an anthelmintic. The phytochemical investigation of the seeds resulted in isolation of three fatty acid, namely n-docosanoic acid, n- octacosanoic acid, dotriacontanoic acid and two glycosides which were identified as ?-sitosterol xyloside (stigmast-5-en-3-ol-3-O-?-D-xylopyranoside), a rare steroidal xyloside isolated from B. monosperma, and buteagibrenol glycoside (3,4-dihydrozingiberen-14-ol-?-D-glucopyranosyl-(1?4)- ?-D-glucopyranoside), this is a new sesquiterpene glycoside isolated from a plant source for the first time. Ficus bengalensis family- Moraceae is a large tree with aerial roots. Leaves are good for ulcers; aerial roots are useful in gonorrhoea and seeds and fruits are reputed as a refrigerant and tonic. The exudates and some phytoconstituents isolated from the bark are being used to treat diabetes.

Ms ASHNA PARVEENImage Delegate ID Theme Details


Research

Category : OthersOrganisation : AMITY

INSTITUTE OF BIOTECHNOLOGY, AMITY UNIVERSITY LUCKNOW

CAMPUS, UTTAR PRADESHDesignation : RESEARCH

SCHOLAR

Abstract: The Nanoparticles (NPs) are metal atom clusters of range 1-100 nm, highly promising due to their wide range of applications in commercial products. Several methods are used for synthesis of nanoparticles (NPs) such as physical, chemical, enzymatic and biological. The biological synthesis of nanoparticles involves microbes and plants. Biogenic approach gives an environment and eco friendly possibility that employs the biogenic substance as reducing and capping agents. The current study involved biosynthesis of Nickel nanoparticles (NiNPs) using biogenic approach via biochemical reduction by leaf extract of Musa balbisiana (Banana, capping and stabilizing agent) with aqueous solution of Nickel Sulfate (NiSO4. 6H2O, precursor). The plant extract was prepared by boiling leaves at 100°C temperature for 30 minutes followed by filtration using Whatman qualitative filter paper No. 1. The resulting filtrate was treated with the aqueous solution of salt (1mM). The resulting mixture was incubated at 80°C for half hour, checked by spectrophotometer. There was a powerful evidence for the surface plasmon resonance (SPR) of NiNPs described by UV-vis. spectroscopy in range of 200-800 nm along with a characteristic peak appeared at 263.5 nm and green color turns to dark green color. The synthesized NiNPs showed good catalytic activity towards anthropogenic pollutant Methylene Blue with sodium borohydride. Where, there was significance reduction of absorbance of Methylene Blue from 0.0650 to 0.0245 at 663 nm, under incubation period of 30 minute. The decreasing absorbance also resulted in reduction in bluish color of Methylene Blue and therefore, assisting in environmental protection. Keywords: Nanotechnology, Green synthesis, SPR, Nickel Sulfate, NiNPs

Mr Zeeshan RafiImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Integral


Scholar

The non-enzymatic glycosylation is a very common phenomenon in the physiological conditions which ismediated by distinct chemical entities containing reactive carbonyl species (RCS) and participate inthe modification of various macromolecules particularly proteins. Till date, various carbonylspecies i.e. glucose, fructose, D-ribose and methylglyoxal have been used frequently to assess thein-vitro non- enzymatic glycosylation. Similarly, 2'-Deoxyribose is one of the most abundantreducing sugar of the living organisms which forms the part of deoxyribonucleic acid and may reactwith proteins leading to the production of glycation intermediates, advanced glycation end products(AGEs) and highly reactive RCS. Thymidine phosphorylase derived degradation of thymidine contributesto the formation of 2'-Deoxyribose, therefore, acting as a major source of cellular 2'-Deoxyribose.Since albumin is a major serum protein which plays various roles including binding and transportingendogenous and exogenous ligands, it is more prone to be modified through different physiologicalmodifiers, therefore it may serve as a model protein for in-vitro experiments to study the effect of2’Deoxyribose mediated modifications in the protein. In this study, Bovine Serum Albumin (BSA) wasglycated with 50 and 100 mM 2'-Deoxyribose followed by examining secondary and tertiary structuralmodifications in BSA as compared to its native (unmodified) form by using various physicochemicaltechniques. We evident a significant modification in 2'-Deoxyribose-glycated BSA which was confirmedthrough increased hyperchromicity, keto amine moieties, carbonyl and hydroxymethylfurfural content,fluorescent AGEs, altered secondary structure conformers (? helix and ? sheets), band shift in theamide-I region and diminished free lysine and free arginine content. These modifications werereported to be higher in 100 mM 2'-Deoxyribose-glycated BSA than 50 mM 2'-Deoxyribose-glycated BSA.Our findings also demonstrated that the rate of glycation is positively affected by the increasedconcentration of 2'-Deoxyribose. The results of the performed study can be implied to uncover thephenomenon of serum protein damage caused by 2'-Deoxyribose leading towards diabetic complicationsand number of AGE-related diseases.

Mr VAIBHAV PANDEYImage Delegate ID Theme Details


Research

Category : OthersOrganisation : IIT BHU


In view of the demand of porous materials for wide range of applications and considering the globaldrive towards product development through new/modified compositions and processes, alternatematerials and methods, the present work is focused on the development of plaster foam shapes withwide range of porosity and desired dimensions suitable for variety of applications. The mainobjective was to formulate wide range of compositions using a foaming agent and suitable additive indifferent proportions with Plaster of Paris powder. Also, the work was focused to optimize theamount of foaming agent and the additive in the mix composition. Optimization of various keyprocessing parameters was also carried out in order to obtain plaster foam shapes with wide range ofspecific gravity, pore microstructure having variable shapes and dimensions. The specific gravitycomes out in the range of 0.5 to 1.5 with the porosity ranging from 10-50%.

Mr RITESH KUMAR GUPTAImage Delegate ID Theme Details


Research

Category : OthersOrganisation : AcSIR-AMPRI

BhopalDesignation : PhD Scholar

Design & Development of Advanced Microwave Induced Novel Nano Carbon Black Reinforced Shape Memory Polymer Ritesh Kumar Gupta1, S. A. R. Hashmi1, 2, Sarika Verma1, 2 , Medha Mili 2, Nikhil Gorhe2 1 Academy of Scientific and Innovative Research (AcSIR), AMPRI Bhopal, India 2- CSIR-Advanced Materials and Processes Research Institute, (AMPRI) Bhopal, Madhya Pradesh, India Contact Author’s e-mail address: [email protected] Abstract: Smart and Intelligent materials with the superior qualities as well as cost effectiveness are the requirement of future technologies in various strategic sectors useful for broad application spectrum. For the first time, we report a unique method wherein the novel carbon nano black derived from rice husk as resource material was successfully utilized for designing & development of advanced microwave induced novel nano carbon black reinforced shape memory polymer. The developed shape-memory thermoplastic polyurethane/nano carbon black composite microwave (mw)-induced and was prepared through melt compounding technique. These, spherical nano carbon black acts as a strong microwave absorbing material which are strongly physically linked into polymer matrix. The detailed characterization was done using various sophisticated complimentary techniques using FESEM, EDX, AFM, IR, and XRD. Further the effect of NCB on thermal, mechanical, viscoelastic and shape memory properties of thermoplastic polyurethane was also investigated. The results showed that NCB in SMPU matrix provides developed product played a dual role; one by being a good reinforcement and another being an excellent MW-induced shape memory effect (SME) along with a higher equilibrium temperature under MW irradiation. Also, the Addition of NCB in SMPU further improves the mechanical strength and young’s modulus of developed composite. Maximum recovery stress was obtained for 1 phr NCB addition with negligible effect on shape recovery. Similar trend was obtained for storage modulus.MW-induced SMPs offered great advantages such as instant recovery, high recovery rate, and can be operated remotely. The developed novel product finds its potential applications in various areas like the fast and bio inspired SMPs used as MW-responsive sensors, implantable devices, remote sensing application etc.

Keywords: Shape Memory Polyurethane, Nano Carbon Black, Microwave Induced Shape Recovery, Dynamic Mechanical Analysis

Mr Mirwaiz RahamanImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Jalpaiguri Govt. Engineering CollegeDesignation : Assistant

Professor

In this work, we have developed a technique to recognize certain types of human activities usingsensor data from Smartphone. For validation, we have used publicly available activity recognition(AR) database which includes labeled data collected from 30 subjects in age group of 19-48 years.Each person performed six different activities, walking on flat ground and up and down stairs,sitting, standing, and lying down, wearing a Smartphone around the waist, used for data collection.The Smartphone which contains an accelerometer and a gyroscope for measuring 3-axial linearacceleration and angular velocity respectively at a constant rate of 50Hz, sufficient for capturinghuman body motion. The accelerometer in the mobile device provides the XYZ coordinate values, whichis used to measure the position and the acceleration of the device. The rotation direction andposition is measured using gyroscope. Accelerometer along with the linear acceleration and gyroscopewill provide results close to accuracy. The gyroscope helps us to get the angular velocity in3-axial angular velocity retrieval. The raw data was then pre-processed by applying noise filtersand then sampled with fixed-width sliding windows of 2.56 sec and 50% overlap. From each window, avector of 17 different features of body acceleration is obtained by calculating variables from theaccelerometer signals both in the time and frequency domain (e.g. mean value, standard deviation,signal magnitude area, entropy, signal-pair correlation, etc.). The testing dataset consists ofvectors each containing 561 features and represents 2.56 seconds of time. Each vector encodescharacteristics such as the tri axial average, maximum, and minimum acceleration and angularvelocity over the given interval, as well as Fourier transform and autoregressive coefficients. Weused this dataset for experimental validation of our activity recognition approach. With a basicuntuned model the activity of the Smartphone user can be predicted with an accuracy of 95% using thelightGBM classifier.

Ms Hafsa BashirImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Barkatullah

University Bhopal Designation : Research

Scholar

Impact of Population Explosion on Ecological Resources and Quality of Life: A Case Study of Bhopal (Madhya Pradesh). Hafsa Bashir1*, Dr. R. D. Singh2 1Research Scholar at Barkatullah University Bhopal (M.P) 2 H.O.D(Rtd), Department of Regional Planning and Economic Growth Barkatullah University, Bhopal (M.P) [Corresponding author email: [email protected]]

Abstract

The ecological resources are exploiting rapidly for the economic growth and fulfilling of human needs (energy, food, space and resources to survive) in an irrational way, a negative implication of accompanying environmental degradation. Due to the rapid increase in the human population on earth, the degradation of the environment is continuously going on. In this paper, an attempt has been made to examine the nexus between population explosion and consumption of the ecological resources. Both primary and secondary sources of data have been approached to full fill the objectives of the study. The study is limited to the Bhopal city of Madhya Pradesh. It was found that there is a negative correlation between population density and quality of life. The area where the population density is high, quality of life like health, education, economic conditions, etc is very poor. Access to ecological resources is very high in highly populated areas of old Bhopal. The agricultural lands surrounding Bhopal city is converting very rapidly into residential without sustainable infrastructure services and urban planning guidelines, directly contributed to the degradation of the environment. With the help of satellite images and maps, it was found that the vegetation and water bodies’ area has been shirked in the city; the forest area and wetlands have been encouraged due to the anthropogenic facts resulting in degradation and depletion of ecological resources. The awareness towards sustainable use of ecological resources was found very high among the people living in the newly developed areas of Bhopal as compare to the old Bhopal. So it can be concluded that increasing population has resulted in serious ecological and environmental conflicts in the natural setting of the Bhopal city of Madhya Pradesh.

Keywords: Population Explosion, Health, Land and soil degradation, Deforestation, Climate change, Air and water pollution.

Mr ISHWAR CHANDRA RAHIImage Delegate ID Theme Details


Research

Category : OthersOrganisation : BSIP LucknowDesignation : TECHNICAL

OFFICER

The sedimentary succession of Sonari Lignite field, Barmer Basin (Akli Formation, Western Rajasthan, India) which is exposed in an open-cast lignite mine, interbed several lignite seams that alternate with fossiliferous carbonaceous shale, grey shale and widespread siderite bands. Geochemistry including analysis of the Carbon isotope (?13C) and rare earth elements (REE) have been carried out in the sediments of Sonari Lignite field to examine the palaeoenvironmental conditions .?13C values show variation of?4.0‰ with maximum excursion (?29.00 ‰) in Grey Shales at the middle part and minimum (?25.00‰) in lateritic clay towards the terminal end. Total REE concentration varies (due to lithology) from 77.12 ppm to 782.16 ppm with an average of 240.80 ppm. The chondrite and PAAS normalized patterns exhibit low Ce anomaly, enriched LREE, and depleted HREE,medium Y/Ho ratio(~15~30) along with positive correlation between Y/Dy and Y/Ho ratio.The overall REE abundance and distribution suggests highly reducing environment under the shallow marine transgressive phase of deposition. The depositional setting, biostratigraphical constrained age along with?13C values and lower TOC suggested an intense warm period, that might be coeval with the Paleocene-Eocene Thermal Maxima event (PETM).

Mr Prabhanjan GiramImage Delegate ID Theme Details


Research

Category : OthersOrganisation : ACSIRDesignation : Senior

Research Fellow

Skin acts as first line defense against foreign pathogenic invaders, chemicals and different typesof microorganism. The internal delicate organ is protected by virtue of the homeostasis. If skin isaffected by any defect, it leads to serious health problem and progresses into chronic and acuteinfection. In case of hospitals acquired infection, patients subjected to surgical intensive careunit, are always prone to develop high risk of mortality and morbidity caused by bacterial infectionand associated contagious, non-contagious diseasesin the last decades of 21st century,fluoroquinolone were prescribed in community, hospital acquired infection management in healthcarescenario. Moxifloxacin is a fourth-generation fluoroquinolone (Topoisomerase-II and IV inhibitor),similar to that of prototype fluoroquinolone against gram-negative bacteria (E. coli) and profoundactivity against gram-positive bacteria including S. aureus widely used in the clinics.Antimicrobial electrospun nonwoven Eudragit L-100 nanofibrous mats containing Moxifloxacinhydrochloride were fabricated for fast dissolving drug delivery systems associated with woundinfection. The morphological characterization of nanofibers using ESEM revealed that the averagediameter of non-woven nanofibrous mats ranges 200?600 nm. The nanofiber showed cylindrical shapewith crack on the surface. Differential scanning calorimetric and Wide Angle X-ray diffractiondemonstrate that the drug exists in an amorphous state in the nanofibers. Nanofibrous mats were alsotested for mechanical strength, contact angle, swelling assay, haemolysis and disintegration test.In vitro disintegration tests demonstrated that the dissolution of Eudragit L-100 fiber mats waswithin 25 s which was higher compared to the pure drug. The Eudragit nanofibers showed pH-dependentdrug release profiles, with slow release at pH 1.2 and burst release (around 30 s) at pH 6.8. Thein-vitro quantitative and qualitative antimicrobial assay showed that the developed Eudragit L-100nanofibrous mats with MOX-HCL concentration of 1%, 5% and 15 wt% exhibited antibacterial activitiesagainst both gram positive (Staphylococcus aureus) and gram negative (Escherichia coli) bacteria.The in vitro cytotoxicity assay using mouse fibroblast NIH/3T3 cells demonstrated significantbiocompatibility of nanofiber. As per the results of biological evaluation, Eudragit L-100nanofibrous mats with 1wt% MOX-HCL could be a suitable substrate for biomedical applications.Eudragit L-100 nanofibrous mats containing Moxifloxacin hydrochloride (MOX-HCL) showed immediateDDSs for localized drug release in the wound infection at slightly acidic or alkaline conditionswhere faster drug release rate is required for wound healing. Reduction in the level and number ofwound infections is a necessity for desired outcomes and cost-effective management of wounds.

Mr RIMPY CHETIAImage Delegate ID Theme Details


Research

Category : OthersOrganisation : BIRBAL SAHNI

INSTITUTE OF PALAEOSCIENCES


During early Palaeogene time, the equitorial positioning of the Indian landmass and the favorable climatic conditons led to the developement of thick lignite sequences along the shoreline of palaeotethys. The present study focuses on the lignite bearing sequence exposed in the Barsingsar lignite mine of Bikaner-Nagaur Basin. The lignite belongs to the Palana Formation of early Palaeogene age. The organic geochemical studies show that the distributions of n-alkane ranges from n-C13 to n-C33 with a bimodal distribution. The Cmax varies from sample to sample indicating variation in the input of organic matter. In most of the samples, the Pr/Ph ratio is greater than 1 suggesting oxic conditions. However, most remarkable is the presence of diterpenoid hydrocarbons in all the studied samples (throughout the studied section) suggesting gymnosperm (conifer) input whereas angiospem marker is identified only in one sample. The lignites of Barsingsar are predominantly composed of huminite macerals (av. 75%), followed by inertinite macerals (10%), liptinite content (9%). and mineral matter (6%). The dominance of detrohuminite (attrinite + densinite) with respect to telohuminite (textinite + ulminite) suggests that the organic matter has undergone higher degree of degradation; as is also indicated by the frequent occurrence of funginite. The lignites are formed in limnic and rheotrophic conditions based on the petrographic indices. The deposition took place possibly in a marshy depositional setting. The occurence of macrosporinites produced by gymnosperms supports the diterpane composition of the lignites. Rare angiosperm markers and a high relative abundance of gymnosperm markers suggest the possibility of conifer dominant forest flourish in the area during sedimentation, and probably with a relatively cooler climatic condition. .

Ms VIDYADEVI BHOYARImage Delegate ID Theme Details


Research

Category : OthersOrganisation : University

Department of Pharmaceutical Sciences, Rashtrasant

Tukadoji Maharaj Nagpur University, Na

Designation : Ph.D Research Scholar

Orodispersible films (ODF) are ideal for many groups of patients including geriatrics, paediatrics,and psychiatrics as well as for those people who have difficulty in swallowing. Asthma is a commonchronic disorder of the airways that involves a complex interaction of airflow obstruction,bronchial hyperresponsiveness and an underlying inflammation. Leukotrienes are inflammatorymediators. Montelukast sodium (MTS) is a selective and orally active leukotriene-receptorantagonist, a powerful antiasthma drug which has oral bioavailability of 60-65%, short half life of3-6 h and it undergoes little hepatic metabolism. Bioavailability of drug in film dosage form isgreater than the convectional dosage form. The objective of the present study deals with design,optimization and evaluation of ODF of MST for oral administration with view of fast onset of actionin asthmatic condition. Hence in the present work, an attempt has been made to provide fastdissolving drug delivery using water soluble polymers with MST as the model drug. The films wereprepared by solvent casting method using Lycoat RS 720, polyvinyl alcohol (PVA) as polymer,polyethylene glycol 600 as plasticizer and Hydroxypropyl ?-Cyclodextrin as solubiliser in differentratios. Optimization achieved using 32 full factorial design where Lycoat RS 720 (X1), propyleneglycol (X2) were independent variable and dependent variable were selected as disintegration time,folding endurance and in vitro drug release profile. Depending on the desirability the solutiongenerated by expert design, the ODF3 batch was selected and film were characterized and evaluated.Formulation ODF3 was transparent in appearance, weight uniformity 22.13±0.18 (mg±SD), thickness(0.020 mm), moisture content (1.97±0.10), folding endurance 168 (no.), % drug content(95.28±0.28), surface pH (6.80±0.14) that is in salivary pH range. Formulation ODF3 disintegratedin 27.46±0.5 seconds, maximum %drug release of 94.68±1.02% in 10 min. The final optimizedformulation (ODF3) was compared with marketed product of Montair–Montelukast sodium film coatedtablets which showed 96.5±1.4% drug release in 30 min. Ex-vivo permeation study were carried out onbuccal mucosa of goat, and stability studies conducted at 40ºC/75%RH, showed no significant changein drug content, surface pH, and in vitro drug release. Thus from present work, it can be concludedthat Lycoat RS 720 can be the good candidate for the ODF, and ODF can be an innovative and promisingnovel approach for the delivery of MST which increases efficacy and patient compliance for thetreatment of asthma.

Dr Anandaraman PVImage Delegate ID Theme Details


Research

Category : OthersOrganisation : School of Ayurveda, Amrita Vishwa

VidyapeethamDesignation : Professor

Inter-Disciplinary research in Ayurveda is the area where the integration of Data, tools, concepts, theories, methods from various disciplines other than Ayurveda occurs. This is done to understand the basic principles of Ayurveda, Mechanistic actions of Ayurveda medications and therapies, thereby developing a strong scientific/ Evidence base for Traditional Indian Medicine. Also, such researches can complement each other. Faculty of Ayurveda is very orthodox in terms of further scientific explorations, which hinders the widespread of this ancient wisdom. Even in the Postgraduate and doctoral researches, such approaches are rare. We have initiated few interdisciplinary researches by integrating Mechanical Engineering, Metabolomics, Psychometric, biomedical Engineering, Bio-Informatics, Modern medical sciences, Dental Sciences etc., few of these studies are completed successfully and few are on the way of its progress. We will elaborate on the challenges faced during these studies in this paper in detail. Bringing all the experts of various disciplines around the table is a herculean task especially when it comes to Faculty of Ayurveda. Apart from that lack of awareness of the Ayurveda Scholars regarding the recent advancements in the field of science and technology is a real hurdle for an interdisciplinary approach. We could manage these situations by initiating reorientation programs to Ayurveda Postgraduate and Doctoral Scholars. Identifying the likeminded people who work for the benefit of humanity is a little difficult but not an impossible thing. Since the University was multidisciplinary we were able to collate all the required factors at a single point even with little struggle. Scientists from engineering background and Basic Life sciences were more open to such discussions. But it was hard to crack the nut when it comes to scholars of Western BioMedicine. This interdisciplinary approach paved a path to a newer direction to Ayurveda research. For example, in various clinical trials we were assessing the outcome measures by using modern assessment tools, which always found less effective, but as we started to use our own tool developed with psychometric principles gave more accuracy and clarity. Another instance was an interdisciplinary collaboration with mechanical engineering could develop a novel Instrument (“Automated Portable Shirodhara Machine”) used for Ayurveda Therapy. This could improve not only the efficacy but also could cut down the cost of the procedure in terms of the quantity of medicine used and the human workforce adopted. Finally benefitting the end-user, the Patient. Keywords: Ayurveda, Inter-Disciplinary, Traditional Indian Medicine, Evidence Base

Mr MOORTHY NAIRImage Delegate ID Theme Details


Research

Category : OthersOrganisation : CSIR-National

Environmental Engineering Research Institute

Designation : Project assistant

Economic valuation of environmental parameters is becoming more and more important, as the world is understanding the use of it as a powerful tool for safeguarding the environment and penalising the polluters. Valuation of environmental damages serves two purposes. One is understanding the total value of environmental damages occurred during an incident for determining the maximum amount of financial liability of the responsible party. The other is of determining the value of restoration for different options for environment. Ecosystem services valuation discuss the value that otherwise would have not been considered or valued in the usual system of measuring the gross domestic product of any country. The ecosystem valuation, thus helps in realising the actual benefits of the ecosystem and can be compared with the business as usual case presented. In India, the case of ecosystem services valuation and environmental damage cost assessment has gained importance since the Hon’ble National Green Tribunal (NGT) has taken a note of polluter pays principle and is suggesting to evaluate the damages and restoration costs in its cases. Hence, it is important to develop India based valuation, in order to crosscheck and sometimes counter the valuations given by international groups. A detailed methodology is developed for valuation of air pollution parameters based on cost of illness and value of statistical in Indian context. The valuation suggests the actual damages to be about 60% of what has been reported by WHO, since the values used are India specific values. To present, case study of Nagpur city is discussed in detail. Further, the damages with respect to wastewater generation and discharge without treatment into river ecosystem is also discussed. Data on water quality of Nag River was used to estimate ecosystem damage of river using avoided cost method and was found to be high as around 500 million INR, reported in 2019 year values. Damages were of that high order due to high values of biological oxygen demand (BOD), Chemical oxygen demand (COD) and suspended solids. Mortality/Morbidity damage cost as an impact of air pollution (PM10, SO2 & NO2) for the city was studied using above approaches and was found to be around15 billion INR, reported in 2019 values. A very high damage cost due to total mortality because of particulate released in ambient air was observed. SO2 concentration was higher during the days of November which added up to the total health damage cost.

Mr Ashish KumarImage Delegate ID Theme Details


Research

Category : OthersOrganisation : GGI


Robot and automation are very popular in these days, and technology is growing very fast. There is need to automation in various fields. So our project is multipurpose humanoid robot which concept can be used in various fields such as education, industries etc. if we are talking about machinery then the machinery needs the automation and monitoring. All these can be implemented with our project. Which is humanoid robot which is not only capable of automation but is also capable of monitoring and data access and transfer. We can apply our project in any prospective field just taking the example of Traffic .our Robot which is capable to monitoring and problem solving in the case of huge traffic. Developing humanoids poses fascinating problems in the realization of manipulation capability, which is still one of most complex problem in robotics. For its scientific content and for its utility in the most robotics applications, the problem of manipulation has been deeply investigated and many results are already available, both as hands and sensors and as control schemes

Ms SINI S RAJImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Indian Institute of

Information Technology and Management-Kerala (IIITM-K)Designation : RESEARCH

SCHOLAR(M.Phil)

Neurodegenerative diseases are common in the elderly and result from progressive and irreversibleneuronal damage (ultimately resulting in the death of nerve cells or neurons). A typicalneurodegenerative disease (collectively called degenerative Parkinsonian disorders) mainly a?ectneurons in the brain regions controlling movements and posture. Parkinsons disease (PD) is thecommonest among this group, others being Multiple System Atrophy (MSA), Progressive SupranuclearPalsy (PSP), etc. All these diseases cause abnormalities in body movements and posture. ThePathological deposition of iron is seen in the degenerating brain areas in these diseases. Thepattern of iron deposition in subcortical brain regions (also called deep gray matter [DGM]structures) like caudate nucleus, putamen, globus pallidus, red nucleus, and substantia nigra couldbe used in di?erentiating various neurodegenerative parkinsonian disorders like PD, MSA, and PSP.QSM (Quantitative Susceptibility Mapping) is a Magnetic Resonance Imaging (MRI) based techniquewhich helps to non-invasively quantify the iron deposition in di?erent brain areas. The techniquecan be used to quantify the iron deposition in the DGM structures enumerated above. For this, theregions of interest (ROIs) have to be drawn manually by experienced radiologists, which is atime-consuming task and potentially associated with inter-rater variations. The automatedsegmentation of ROIs (The deep gray matter structures) for QSM analysis has a pivotal role to playin the area of medical imaging pertaining to degenerative Parkinsonian disorders. The proposed modelcan automatically segment the regions of interest from the brain MR image, based on pixel-labelbased semantic segmentation. Segnet is a pretrained deep learning model used to perform thepixel-label based semantic segmentation, which can automatically segment the deep gray matter (DGM)structures of the brain. Thus the amount of iron deposition can be easily calculated from thesesegmented image using QSM (Quantitative Susceptibility Mapping) techniques.

Mr OBADIYA RAIImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Sikkim


Identification of molecular marker for tolerance against Phytophthora species in Sikkim mandarin (Citrus reticulata Blanco) *Obadiya Rai1 and Sujata Upadhyay2 Sikkim University, Gangtok [email protected]

Abstract: Phytophthora sp. being hemi-biotrophic in nature has evolved as most destructive pathogen in citrus orchards of Sikkim causing gummosis and root rot. Due to their wide host specificity and radical invasion mechanisms, the morphological and molecular characterization of the pathogen isolates become imperative to develop the management module. Simultaneously, the screening of Sikkim mandarin lines which shows the resistance based on sick plot test may be further utilized for transcriptomics studies. However, many conventional methods were used to study the Phytophthora but proved to be inefficient, thus molecular based techniques may be efficient in mapping the variation in gene expression in the chromosomal region. There may be differential gene expression by plants post inoculation which represents the genetic polymorphisms that are located in the other regions of genome which helps in identifying the promising candidate gene/s for the tolerance against Phytophthora sp. Keywords: Gene expression, Phytophthora, Sikkim mandarin, Tolerance, Transcriptomics References Ajengui, A., Bertolini, E., Ligorio, A., Chebil, S., Ippolito, A., Sanzani, S. M., 2018, Comparative transcriptome analysis of two citrus germplasms with contrasting susceptibility to Phytophthora nicotianae provides new insights into tolerance mechanisms. Plant Cell Reports, 37:483–499. Boava, L. P., Cristofani-Yaly, M., Mafra, V. S. Kubo, K., Kishi, L. T., Takita, M. A., Ribeiro-Alves, M., Machado, M. A., 2011. Global gene expression of Poncirus trifoliata, Citrus sunki and their hybrids under infection of Phytophthora parasitica, BMC Genomics, 12: 39. Das, A. K., Bawage, S.S., Nerkar, S.G. and Kumar, A., 2013. Detection of Phytophthora nicotianae in water used for irrigating citrus trees by Ypt1 gene based nested PCR, Indian Phytopath. 66 (2): 132-134. Lima, R. P. M., Curtolo, M., Merfa, M. V., Cristofani-Yaly, M., Machado, M. A., 2018. QTLs and eQTLs mapping related to citrandarins resistance to citrus gummosis disease. BMC Genomics, 19: 516.

Ms PRANITA KANOJIYAImage Delegate ID Theme Details


Research


pharmaceutical sciencesDesignation : PhD research

scholar

Malaria is the most prevalent parasitic disease caused by Apicomplex protozoan of the Plasmodium (P.) genus. It is one of the most serious vector-borne diseases affecting millions of people which reside exclusively in the hotter and moist areas of the tropics. Therefore, WHO recommends the use of artemisinin-based combination therapy (e.g., artemether/lumefantrine) in order to delay the development of resistant strain. Lumefantrine (LUM) is an antimalarial drug having poor aqueous solubility. Solvent evaporation technique was used to prepare solid dispersions (SD) with Soluplus® (SOL) and Lutrol F68 (LF 68). Based on the preliminary solubility studies, the medium selected for the dissolution studies was Hydrochloric acid (HCl) 0.1 N pH 1.2 with 1% Myrj 52 (surfactant) and drug solubility was analyzed by high performance liquid chromatography method. The prepared SD was characterized by differential scanning calorimetry, fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy and results showed that LUM, SOL and LF 68 had groups that form interaction between them and this led to conversion from crystalline to amorphous form. Based on solubility studies and in vitro dissolution, the ratio of LUM: SOL: LF 68 was optimized to 1:2:1. In vitro dissolution study of optimized formulation of LUM containing (1:2:1) showed increased drug release and was found to be 98.22% within 20 mins in 900 ml of 0.1 N HCl with 1% Myrj 52 at 37±0.5 °C by HPLC method as compared to marketed formulation. The SDs (capsule form) and marketed tablet Lumerax-20 DT were studied for drug release. In vitro antimalarial screening was performed for the optimized formulation using Plasmodium falciparum 3D7 (Chloroquine sensitive) strain. In vitro cytotoxicity was performed using Vero cell line by MTT assay. The selectivity index value of LUM SD depicts its non-toxicity. Stability studies were carried out for three months and the SDs were evaluated for the drug content and change in weight. No significant changes were observed after three months in the content and weight of SDs and were found to be stable.

1. Fule, R.; Meer, T.; Sav, A.; Amin, P. J. Pharm. Investig.2013, 43,305–321. 2. Umapathi, P.; Ayyappan, J.; Quine, S.D. Trop. J. Pharm. Res.2011; 10, 643-653.

Ms NUSRAT SAYYADImage Delegate ID Theme Details


Research

Category : OthersOrganisation : RASHTRASANT TUKADOJI MAHARAJ NAGPUR UNUIVERSITY , DEPARTMENT

OF PHARMACEUTICAL SCIENCES NAGPUR


A QSAR study was performed on thirty-five compounds of known series having pyrazole nucleus using Accelrys Discovery Studio Vs 2.1.0.8130. On basis of QSAR study predicted molecule synthesized; 1-(5-(substitutedyphenyl)-3-(substitutedphenyl)-4, 5-dihydropyrazol-1yl) ethanone have been synthesized as per scheme. In the presence of base, substituted acetophenone and substituted benzaldehyde undergo Claiesen-Smith condensation reaction and form chalcone derivatives. In next step sub. Chalcone undergo cyclisation with hydrazine hydrate and form final pyrazole moiety to achieve target compounds which are predicted from QSAR studies. The compounds synthesized were purified and characterized by their physical and spectral data. Anti-cancer activity of all synthesized compound will be evaluated for in-vitro measurement by MCF-7 cell line through SRB assay. Results of anticancer activity shows that 1-(5-(4-Chlorophenyl)-3-(4-ethoxyphenyl)-4, 5-dihydropyrazol-1-yl) ethanone gives significant IC50 0.010 µM value. With the help of the QSAR analysis and the GFA model chloro substituted compound showed higher activity and hence synthesis carried out. All the synthesized compounds were characterized by physico-chemical parameters and spectral interpretations such as IR, NMR and mass spectroscopy. SRB assay were performed and compound (PCP-101) 1-(5-(3, 4-dimethoxyphenyl)-3-(3-hydroxyphenyl)-4, 5-dihydropyrazol-1yl) ethanone possess less activity whereas compound 1-(5-(4-Chlorophenyl)-3-(4-ethoxyphenyl)-4, 5-dihydropyrazol-1-yl) ethanone (PCP-102) shows good activity. So, finally we concluded that pyrazole has vital need for treatment of Cancer. QSAR analysis and the GFA model help in the prediction of the biological more than the marketed product. Therefore 1-(5-(substitutediphenyl)-3-(substitutedphenyl)-4, 5-dihydropyrazol-1yl) ethanone synthesized and screened for anti-cancer activity. Synthesized compound 1-(5-(4-Chlorophenyl)-3-(4-ethoxyphenyl)-4, 5-dihydropyrazol-1-yl) ethanone (PCP-102) (IC50 = 0.010 µM) give potent activity than the marketed product and this way it is better candidates for further study. REFERENCE 1. Osama, I.; Mohamed, M.; Samy, M.; Christophe, P.Eur. J. Med. Chem., 2009, 44(9), 3746–3753. 2. Hassan, Y.Molecules 2013, 18(3), 2683-2711. 3. Samir, B.; Wesam, K.; Ahmed, A.F. Eur. J. Med. Chem., 2011, 46(6), 2555-2561. 4. Leonetti, F.; Favia, A.; Rao, A.;Aliano, R.;Paluszcak, A.; Hartmann, RW.; Angelo, C. J. Med. Chem., 2004, 47(27), 6792-6803.

Dr Manas SahaImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Siliguri Institute of Technology


Over the last few years, Machine Learning (ML), a branch of Artificial Intelligence is widely used in our day to day life. Some applications are biometrics, flood prediction, text mining for vernacular language interpretation, traffic signal control, plant disease detection, spam detection, app based skin cancer detection. This work presents a common skin disease called vitiligo detection using supervised ML. Vitiligo is characterized by the damage of skin color pigment forming cells called melanocytes leading to white patch. It can spread over any part of the body. The proposed work is divided into two phases. In the first phase, data mining from the skin disease images is done by a mathematical transform called wavelet [1]. Here, skin disease images are of two types -vitiligo and non-vitiligo images. Non-vitiligo means it can be of any skin disease like rosacea other than vitiligo. The second phase includes supervised ML technique used to analyze the pattern of input data mapped with corresponding target data to detect vitiligo images from the skin disease images [2]. Wavelet is applied to skin image to decompose it into 1 approximate sub-band and 3 detail sub-bands and collect 4 subband associated energy signatures (features) [1]. The approximation subband is again decomposed into 1 approximate and 3 detail sub-bands. In this way one skin disease image is decomposed thrice generating 12 energy signatures. Based on the literature survey, Daubechies, Discrete Meyer, Symlet and Reverse Biorthogonal wavelets are applied to the skin images to discriminately mine the energy signatures [3]. Using the energy signatures of skin disease images input and target databases are created. A suitable feedforward neural network (FNN) is designed. Using supervised ML algorithm, the FFN network is trained with 80% of the input samples and the remaining 20% of the samples are utilized for validation and training purposes. The result is obtained from the confusion matrix and performance plot of FNN. The different metrices evaluated for vitiligo detection are 1) Accuracy: 82.9%, 2) Sensitivity: 85.7 % , 3) Specificity: 80 % , 4) Positive Predictive Value: 81.1 % , 5) Negative Predictive Value: 84.8% and 6) the best validation is observed at mean square error (MSE) =.13 and iteration =49. Therefore, ML algorithm is successfully applied for vitiligo detection. In future the same approach can be applied for other skin diseases where texture content is very much affected by the disease of interest.

Ms Shivani DixitImage Delegate ID Theme Details


Research

Category : OthersOrganisation : 1 School of

Life Sciences, Jaipur National University, Jaipur-302017,

Rajasthan, INDIADesignation : PHD scholar

Genetic portrait of population of two most diversely populated states of India (Uttar Pradesh and Madhya Pradesh) is explored by analyzing 23 Y- STRs and 12 rapidly mutating Y-STRs in 100 unrelated male individuals to establish parameters of forensic interest. The haplotype diversity, discrimination capacity and matching probability for Y-STRs and RM Y-STRs loci are reported. Power and potential of rapidly mutating Y-STRs over Y STR markers is also presented among pairs of male blood relatives. Keyword: Y-STRs, RM Y-STRs, Forensic genetics, Diversity.

Dr Vikas PaliImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Anand

Agricutlural University, AnandDesignation : Scientist

Varietal identification has attained critical importance worldwide especially in the context ofplant variety protection. The present investigation was undertaken with an objective to developfingerprints of linseed (Linum usitatissimum L.) cultivars, assessing variation within the varietiesand testing the genetic purity of four varieties namely Kartika, Deepika, Indira Alsi- 32 and RLC-92for identification of informative SSR markers capable of distinguishing all four popular varietiesof linseed and seed purity assessment based on SSR markers and morphological traits in linseed wasachieved. About, 90 SSR markers were employed for fingerprinting. Out of these, 28 microsatellitemarkers were found to be polymorphic giving a total of 61 alleles with an average of 2.17 allelesper marker ranging from 2 to 4. The polymorphic information content (PIC) value of each SSR primerpair ranged from 0.37 to 0.75 with an average of 0.41. Nevertheless, two microsatellite markers LU 1and LU 7 differentiated all the four popular varieties of linseed. A multiplex-marker combinationhad unambiguously differentiated varieties from each other through multiplex- PCR which is rapid andcost effective method. Cluster analysis based on Jaccard’s similarity coefficient using UPGMAgrouped the four linseed varieties into two clusters. Cluster I showing 15% similarity while clusterII showing 56% and 32% similarity. The Jaccard’s similarity ranged from 0.10 to 0.60 with anaverage similarity index of 0.34. Based on the molecular marker analysis, the genetic purity rangedfrom 83.3 to 100% while, in case of morphological markers it’s ranged from 85.4 to 100%. Thisdemonstrated the better discriminatory power and efficiency of molecular markers in genetic purityassessments and these markers could even accurately detect residual heterozygosity in the seed.

Dr JANET JImage Delegate ID Theme Details


Research

Category : OthersOrganisation : Sri Krishna

College of Engg. and Technology

Designation : Professor

Abstract Now a days there is immense development in technology. The human population increases day by day, due to increase in population the main defect is road traffic. Due to increase of road traffic there takes place a frequent occurrence of accidents. The accident occurs due to poor quality of roads. To prevent the accidents automatically there are some censoring and chasing methods. With the existing technology the Programming language named as Embedded C and ARM7TDMI-S unit encompasses to provide the proposed system. It use database to store the data. The SIM800 has unique phone number which act as mobile phone and also includes GPS and GSM for vehicle censoring and chasing. Here the GPS is used to find the current location of vehicle and the GPRS send the current information of chasing data to server and the data is send through SMS to the driver. The SIM800 is used to transmit SMS, voice and information which uses very low amount of power consumption. If sensors fixed in the vehicle can protect them from accident. The proposed system protects the car driver from accident and saves human life.

Dr Deepash Shekhar SainiImage Delegate ID Theme Details


Research

Category : OthersOrganisation : D. D. U.

Gorakhpur UniversityDesignation : Assistant

Professor

The effect of spark plasma sintering (SPS) and conventional sintering (CS) on Holmium-substitutedBaZrO3 (BZH) electrolyte ceramics was studied to improve the electrical conductivity forintermediate temperature solid oxide fuel cells (IT-SOFCs). The cubic crystal system with spacegroup symmetry, unit cell parameters and bond length were revealed out through Rietveld refinedX-ray diffraction (XRD) pattern of spark plasma and conventional sintered Ho-substituted BaZrO3ceramic. The microstructure of Ho-substituted BaZrO3 SPS ceramic was found highly dense compare toCS ceramic through FESEM analysis. The average grain size of Ho-substituted BaZrO3 SPS ceramic wasfound to smaller than that of CS ceramic. The Electrical Impedance Spectroscopic (EIS) analysis wasperformed under air and 3% humidified O2 atmosphere as a function of probing temperature from 250 to800 ?C. Thus, the total electrical conductivity of SPS BaZr0.8Ho0.2O3-? ceramic was estimated to be4.91 ? 10-2 S-cm-1 at 700 °C under 3% humidified O2 atmosphere, which is the highest-classconductivity among all reported trivalent cation substituted BaZrO3 ceramics follow by spark plasmasintering.

Ms Swagata BiswasImage Delegate ID Theme Details


Research


INSTITUTE OF TECHNOLOGY DURGAPUR


The search for new physics beyond the Standard Model (SM) is one of the main objectives of the current and future experimental as well as theoretical studies. The decays of B mesons provide information about flavour structure of the SM, the origin of CP violation, the dynamics of hadronic decays and to search for any signal of NP beyond the SM. According to recent picture of analysis of rare B-meson decays, the most famous intriguing patterns of deviations are [8-11]: Angular Observable P_5^' of B?K^* ?^+ ?^- mode. Observation of 2.6? deviation in R_K=(Br(B^+?K^+ ?^+ ?^-))/(Br(B^+?K^+ e^+ e^-)) in the q^2??GeV?^2 bin. Observation of more than 3? deviation in the decay rate of B_s???^+ ?^-. Measurement of R_(K^* )=(Br(B?K^* ?^+ ?^-))/(Br(B?K^* e^+ e^-)). We have planned to study these anomalies in the SM as well as in NP where NP is introduced with the contribution of Z' gauge boson or leptoquark. NP models introduce additional couplings to new heavy mediators at both tree and loop level and these couplings could modify the values of various observables with respect to their SM values. We have studied the B_(s,d)?l^+ l^- decays using? ??^2 fitting method in Z^' model considering the NP effects in the framework of flavour non-universal Wilson coefficients. We have planned to investigate the non-universal leptonic couplings in Z^' model for various channels in accordance with the data of LHCb experiments. These couplings may help the high energy physicists to explore various anomalies in B meson sector as anew benchmark of NP contribution through the exchange of Z^' boson. It would be very interesting to see new results in particular pure leptonic channels which may ultimately introduce a contemporary way towards NP.

Ms Sumitra ShitImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : NIT

JamshedpurDesignation : Student(

passed)

Parameterization of nuclear Hulthén potential for the F and G partial waves Sumitra Shit

Abstract: Hulthén potential is generally used in atomic and molecular physics as a screened coulomb potential but Hulthén potential has the ability to describe the nuclear phenomena. Here simple potential models of nuclear Hulthén type are proposed and parameterized them to reproduce the nucleon-nucleon scattering phase shifts for the F and G partial waves. The phase shifts are computed by applying the phase function method and compared them with the standard data to judge the merit of our models.

Mr SOUMYA CHATTERJEEImage Delegate ID Theme Details


Research


OF KALYANIDesignation : RESEARCH

SCHOLAR

Setting up a portable EDXRF system using bremsstrahlung coming from transmission type x-ray tube for elemental analysis

Soumya Chatterjee* and Debasis Mitra

Department of Physics, University of Kalyani, Kalyani, Nadia, Pin 741235

[email protected]

Abstract: Elemental analysis plays an important role in study of various interdisciplinary scientific fields. In comparison to other elemental analysis techniques like PIXE, NAA, Energy-Dispersive X-ray Fluorescence (EDXRF) is better due to its easy handling and less expensive also. It consists of an x-ray source, x-ray detector and a data acquisition system. Available techniques for elemental analysis are the alpha coefficient method and Fundamental Parameter method (FPM). By using FPM, either one can use monochromatic primary radiation coming directly from radioactive source or fluorescence radiation from secondary target due to incidence of broad primary radiation from x-ray tube to by-pass the separate standard making procedure for each elements in alpha coefficient method which is time taking and costlier also. Sample x-rays are then detected by an x-ray detector. In that case weighted average energy of emitted K???? and K???? of secondary source can be treated as mono-energetic radiation. And by using a suitable peak fitting program, one can calculate elemental concentration with the help of some atomic parameters. Now a day’s very small sized x-ray generator operated by a stable power source like a car battery is commercially available. Since in this case the outward flux is very small, we use the whole bremsstrahlung spectrum as well as characteristic lines depending on anode voltages as an exciter of the sample. We have used a small transmission type portable x-ray generator of Amptek (Mini-X), having 4W power with maximum operating voltage of 50kV. X-rays are detected by using a Silicon Pin detector. Bremsstrahlung spectrum are obtained for various operating voltages of 20kV, 25kV and 30kV and compared with the simulated one which is matched very well for all the cases. We used it to irradiate our sample. In order to use the procedure similar to mono-energetic incident X-ray we have to divide our whole continuous spectrum into large number of energy slices so that each energy slice can be treated as mono-energetic incident X-ray beam and we can perform similar type of analysis. A computer program is developed for this purpose. By using our technique it is seen that the results are in very good agreement with previously published results using monochromatic incident X-ray.

References: 1. A.C.Mandal,S.Santra,D.Mitra,M.Sarkar,D.Bhattacharya,Nucl.Instr.andMeth.B217(2004)(104-112).

Mr Smruti SahooImage Delegate ID Theme Details


Research


Institute of Technology (Indian School of Mines) DhanbadDesignation : Research

Scholar

Organic semiconductors (OSCs) as cost-effective, environment-friendly and biodegradable materials,hold the tremendous promises for organic electronics industries. In this 21st century, organicsemiconducting materials have emerged as potential candidates for flexible electronic andoptoelectronic device applications such as organic light-emitting diodes (OLEDs), organicfield-effect transistors (OFETs), solar cells, organic laser, etc. These materials have manysignificant advantages like low-production costs, mechanical flexibility, the versatility ofsynthesis processes, lightweight, and compatibility with various substrates. Low-temperatureprocessing of OSCs provides additional opportunities for designing flexible integrated circuits,electronic paper, and foldable organic electronics. However, besides the above advantages, enhancingthe charge transport performance and air-stability in these materials has been the major challenge.In this regard, we present the theoretical study of charge transport and optoelectronic propertiesof different OSCs within the framework of density functional theory (DFT). We designed acene andphthalocyanine based organic compounds with substitution of various electron-withdrawing groups(EWGs) such as -F, -Cl, -Br, -I, -CN, -CF3; and reported their charge mobility, air-stability, andoptoelectronic properties. The maximum hole/electron mobility for CF3-substituted tetracene andpentacene was calculated to be 2.17/1.08 cm2/Vsec. Similarly, the maximum electron mobility wasfound to be 2.5 cm2/Vsec and 0.41 cm2/Vsec for F16ZnPc and (CN)8ZnPc semiconductors, respectively.The computed values of electron affinity > 3 eV indicated effective electron-injection inferringenhanced n-type characteristics and air-stability in functionalized phthalocyanine based OSCs.Moreover, the studied optical absorption spectra of the materials appeared in the ultraviolet (UV)and visible regions which is necessary for OLED applications. In addition, the anisotropichole/electron mobility of indolocarbazole derivatives was calculated to be 1.58/0.77 cm2/Vsec andalso reported as better stability than acene compounds. We believe that the studied OSCs can beenvisaged as promising materials for possible applications in organic electronics such as OLEDs andOFETs.

Ms Vineeta ShuklaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : IIT

KHARAGPURDesignation : Research

scholar

Graphene is an ideal system for the study of electrons confined in a two dimensional plane. Graphene shows many exotic phenomena such as fractional quantum Hall effect, Kondo behaviour, metal to insulator transition, superconductivity, etc. The lack of d or f electrons makes it diamagnetic [1]. However, magnetism has been reported in graphene because of the presence of adatoms, vacancies, defects or its edge structure. MnO2 nanoparticle (NP) sprinkled graphene composites are shown to possess a ferromagnetic semiconducting behaviour, wherein an enhanced scattering of electrons is observed at the Curie temperature [2]. An interesting system that can be used to decorate graphene sheets, or derived structures like reduced graphene oxide (RGO), is the Cu1-xNix alloy system, which undergoes a ferromagnetic to paramagnetic quantum phase transition (QPT) in bulk at a critical concentration xc ~ 0.43 [3]. The present work aims at exploring the electrical transport and magnetic behaviours of a set of such nanocomposites formed by decorating RGO sheets with Cu1-xNix (0 ? x ? 1) NP’s. RGO is prepared by reducing graphene oxide, synthesized by Hummer’s method, using hydrazine hydrate. A chemical reflux method is used to prepare the alloy NP’s and disperse them onto the RGO sheets. Scanning and transmission electron microscopy, X-ray and electron diffraction, and X-ray photoelectron and Raman spectroscopy have been used to pre-characterize the samples. Temperature (T)-dependent magnetization (M) and electrical resistivity (?) have been measured using a superconducting quantum interference device and a physical property measurement system, respectively. Simultaneous presence of ferromagnetic, superparamagnetic and ferromagnetic phases is evidenced from the M-T and hysteresis curves for all the x ? 0 nanocomposites. The ?(T) curves indicate semiconducting behaviour for all the nanocomposites, with thermally activated conduction having two distinct activation energies below and above ~ 65 K. Both the activation energies seem to peak at x ? 0.63, which is close to but a little different from xc. This is indicative of a high electron scattering near the bulk critical concentration, most likely as a result of the QPT.

Acknowledgements: The work at Department of Physics, IIT Kharagpur was supported by MHRD, India. References: [1] Chen H. Jian et al., Nature Phys., 2011, 7(7), 535-538. [2] Park C. S., et al. AIP Advances, 2014, 4, 087120. [3] Acker F., Huguenin R., Phys. Lett. 1972, 5, 38, 343-344.

Ms Purabi GhoshImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Fakir Mohan


When two heavy nuclei are collided at ultra relativistic energies, a hot and dense state of matter is formed, popularly known as Quark Gluon Plasma (QGP). The study of QGP matter sheds light on the universe formed microseconds after the Big Bang, which bring about its importance. Also its study will help understand the strong interactions at high temperature and densities. However, the lifetime of the QGP formed in relativistic collisions is very short so it cannot be directly observed. Hence, we require indirect signals to predict its formation and to study the medium properties of bulk. Strangeness enhancement was proposed to be one such signal of QGP formation. To predict the strangeness enhancement from relativistic collisions, we first need to understand the production mechanism of strange hadrons in hadronic medium. In this work, we study the production of multi strange hadrons from Pb-Pb collisions at 2.76TeV energy, LHC(Large Hadron Collider) energy using momentum integrated Boltzmann Transport equation and compared with the experimental measurements.

Dr Praveen KUMARImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : IACS Kolkata


The unique properties of III-nitrides alloys such as direct bandgap tuning from 6.2 eV (UV) to 0.64 eV (IR), high absorption coefficient, high carrier mobility, presence of highly dense (>1013cm-2) positively charged surface donor states, etc., make them one of the ideal materials for future optoelectronic devices. Their outstanding optical properties are capable of revolutionizing LED emitters and solar cell designs. Even greater impact is anticipated for power electronics, photoelectrodes for hydrogen fuel, whereas the presence of electron accumulation at the surface in-particular for high In compositional InxGa1-xN, which makes them very interesting for sensing applications as well. However, the technical challenges related to the growth of high-quality III-nitrides layers on Si substrate, p-doing, etc., reduces their device performance far from the fundamental materials capabilities and limit their full potential to achieve higher efficiency. Therefore, the growth of these nanostructures (self-assembled & selective) directly on Si substrate has been recognized as a very promising approach not only for advanced efficient devices but also for integration of III-nitrides technology with well establish silicon. In my presentation, I will discuss our recent results towards resolving existing issues for the direct growth of nearly defect-free ordered III-nitrides nanostructures with micro/nano dimensions directly on Si substrate for different colored LED emitters. Further, I will summarize our results for solar cells, where we are optimizing the growth of III-nitrides structures for tandem and intermediate bandgap solar cells, with a targeted efficiency > 20%. I will also demonstrate the merits of directly grown InGaN nanostructures on Si(111) without using any buffer layer or external catalyst as a plausible alternative for stable photoelectrochemical water splitting for efficient hydrogen generation. I will also present our recent progress on the development of self-powered, broadband photodetector (365 nm – 980 nm) with high responsivity using Ag-rGO/GaN nanostructured heterojunction comprising transparent metal nanowire network as an electrode. References: 1. K. Sarkar, P. Devi, A. Lata, R. Ghosh, and P. Kumar, J Mat. Chem. C (InPress 2019). 2. K. Sarkar, M. Hussain, P. Devi, KDM Rao and P. Kumar, Adv. Mat. Int. (2019) 1900923 3. P. Kumar, P. Devi, P.E.D.S. Rodrigueze, M. Kumar, V.D. Shivling, R. Noetzel, C. Sharma, R.K. Sinha, M. Kumar, Optical Mat. 79 (2018) 475.

Mr Arul Anne Elden AImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Central University of TamilNaduDesignation : Research

scholar

Ising model is the simplest mathematical lattice model which describes the interaction between thespins, which helps to understand the phase transition in magnetic systems. We investigate the Isingmodel on the honeycomb lattice with additive Gaussian white noise [1]. The Honeycomb lattice havesix nearest neighbours interaction. Each lattice site has a magnetic moment {S_i} as a spinvariable. The spin variable {S_i} can take values +1 or -1. The simulation carried out using theMetropolis Algorithm [2]. This Monte Carlo technique helps to generate the canonical ensemble, andthe evolution of the system depends on their transition probability at any desired temperature. Theacceptance and rejection of the transition probability obey the detailed balance condition forequilibrium system. The sequence of microstates is called Markov chain, which is generated byflipping the randomly selected spin {S_i }=-{S_i}. We have calculated the thermodynamic observableslike average energy (internal energy), magnetization, specific heat capacity, susceptibility. Weobserved that, the Transition temperature T_C varies with increasing randomness of the additivegaussian white noise.

Mr Pradhyut RajkumarImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Gauhati


Scholar

Biomimetics, an interdisciplinary field of research in material science is concerned with theimitation of naturally occurring substances. The challenges faced regarding this mimicking areincreasing the biocompatibility and bioactivity. Hydroxyapatite (HAp) with unit cell formulaCa10(PO4)6(OH)2 is a bioactive mineral that is highly demanding in terms of its biocompatibility.The synthesis of HAp with and without incorporations of Mg and Zn is presented here. The aqueoussolutions of Ca2+ (Ca-solution) and PO43- with CO32- (P-solution) are prepared under biomimeticconditions, keeping the Ca2+ to PO43- molar concentration ratio at 1.67. For Mg and Znincorporations, the Ca-solution is modified by addition of Mg2+ or Zn2+ precursors with totalmolarity same as that of the Ca-solution without Mg or Zn. The X-ray diffraction (XRD) patterns ofthe as prepared samples in powder form reveal nanocrystalline nature of HAp crystals. The fieldemission scanning electron microscopic (FESEM) images show formation of agglomerated globularparticles and the corresponding energy dispersive X-ray spectra (EDS) unveil the formation ofcalcium deficient apatite. Field emission transmission electron microscopy (FETEM) discloses needlelike particles with diameter ~4 nm. This matches well with crystallite size calculated from the XRDpatterns using the Scherrer equation. The selected area electron diffraction (SAED) pattern revealsthe polycrystalline nature showing formation of concentric rings, corresponding to diffraction fromthe lattice planes which also match well with XRD. In conclusion, the nanocrystalline HAp with andwithout incorporation of trace minerals (Mg and Zn) resembling structural similarities with bone orenamel apatite. It has been observed that the incorporations of Zn and Mg induce significantmicrostructural variations in biomimetic apatite.

Mr JNANRAJ BORAHImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Gauhati


(JRF)

High transparency and good conductivity are the two prerequisite conditions for a material to betransparent conducting oxide (TCO). Tin doped indium oxide (Sn:In2O3) or ITO is the most widely usedTCO material due to its excellent electro-optical properties. However, scarcity and toxicity ofindium are the two big issues related to ITO, which compel researchers to find a better substituteof ITO. Al-doped ZnO (Al:ZnO) or commonly known as AZO may be a good alternative to ITO consideringhigh abundance of raw materials, non-toxicity and relatively low fabrication cost associated withAZO. But ageing stability under ambient oxidizing environment is one of the major issues found inAZO. In this work, an attempt has been made to develop stable AZO films with promisingelectro-optical properties. AZO films are deposited by pulsed DC magnetron sputtering underdifferent conditions of gas pressure, sputtering power, deposition time, and different dopinglevels. The deposited films are characterized by using X-ray diffraction (XRD), Field emissionscanning electron microscopy (FESEM), UV-Vis-NIR absorption spectroscopy and four probe resistivitymeasurements. Ageing study is performed under ambient oxidizing environment by recording the sheetresistance for a period of over six months. Optimized films are transparent in the wavelength range400–1100 nm as well as highly conducting with figure of merit of the order of 10-2 ?-1 and ageingstable under natural atmospheric conditions. The findings of the study suggest that AZO can be apotential replacement of ITO as a transparent conductor for variety of applications includingelectronic and photonic devices.

Mr Srikrishna SagarImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : IISER TVM


Solution processed ultra-low voltage operated thin-film transistors needs to be developed urgentlyto minimize power consumption as a requirement considering cost-effective and environmentallysustainable ways. Unconventional and new classes of solution processed high capacitive dielectricfilms with minimal leakage current are emerging as a promising field of research in this direction.Low voltage operated organic thin-film transistors (OTFTs) with relatively high carrier mobilityhave been fabricated by using the redox-electrolyte or anodized aluminum or Tantalum as gatedielectrics in our group. We demonstrated OTFTs with very high performance parameters likeexceptionally large saturation hole mobility (?_Sat) up to 8.0 cm2V?1s?1, operating voltage below1.5V, ION/IOFF ratio as high as 107, and sub-threshold swing down to 177 mV/dec. The specificcapacitance of the gate dielectric is achieved up to ~ 7.0 µF/cm2 using solid redox active polymerelectrolyte and 400 - 600 nF/cm2 using anodized aluminum (Al) or tantalum (Ta) layer of thicknessbelow 10 nm. These large capacitive value of gate dielectrics facilitates to produce charge carrierdensity as high as 1015/cm2 in the channel which is a tremendous achievement in terms of future lowpower applications. Overall, developed OTFTs with the help of high quality alternate gate dielectricmaterials are promising in terms of cost reduction as well as further miniaturization and showspotential with reasonably high performances for further development in the direction of environmentfriendly technology for printed electronics with more complex applications.

Ms LABANYA BHATTACHARYAImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : INDIAN

INSTITUTE OF TECHNOLOGY (INDIAN SCHOOL OF MINES),

DHANBADDesignation : RESEARCH

SCHOLAR

In recent years, the technology used for manufacturing low cost solar cells is predominantly basedon organic semiconducting materials. Besides the high cost-effectiveness, organic solar cell (OSC)materials have significant advantages over inorganic solar cell materials such as lightweight,mechanical flexibility, roll to roll production and eco-friendly nature. Third generation organicsolar cells have still some pivotal challenges for commercial applications such as lowair-stability, high band gap (>2 eV) with smaller optical absorption spectral range. Molecularbackbone engineering with alternating organic donor-acceptor units is one of the effectivestrategies to meet the above-mentioned challenges. In our density functional theory (DFT) study, anew donor-acceptor copolymer comprising (E)-1,2-bis(5-alkyl-[2,3'-bithiophene]-2'-yl)ethene (TVT-T)as donor and 5,6-difluorobenzo[c][1,2,5]selenadiazole as acceptor unit is designed. We modify themolecular backbone by incorporating more stronger electron withdrawing groups (-CN, -NO2) on to thebenzo[c][1,2,5]selenadiazole acceptor unit. The –CN and –NO2 substituted copolymers arecomparatively more air-stable and have broader optical absorption spectral range than the –Fsubstituted ones. The designed compounds yield appreciable hole mobilities (1.21-6.61 cm2V-1s-1)assuring the fact that the modeled copolymers can act as potential donor materials with respect tofullerene analogous acceptor materials. The predicted power conversion efficiencies (PCE) using theScharber diagram are calculated to be as high as ~6%. This study is expected to provide an insightinto the propitious approach of fine tuning of air-stability, optoelectronic, and photovoltaicproperties of organic materials used in OSC technology.

Mr Rudranarayan KhatuaImage Delegate ID Theme Details


Research


physics, iit(ism) dhanbadDesignation : Research

scholar

Since last few years, organic semiconductors (OSCs) have attracted a considerable amount ofattention due to their wide potential applications in various electronic devices such as organicfield-effect transistors (OFETs), organic photovoltaic devices (OPVs), organic light-emitting diodes(OLEDs) and organic solar cells (OSCs). Unlike their inorganic counterparts, organic semiconductingmaterials are cost-effective, lightweight and fairly flexible and also provide the versatility ofchemical synthesis. However, one of the major challenges for the development and fabrications oforganic semiconductors for industrial applications are their air-instabilities. From the theoreticalpoint of view, the air-stability of the organic semiconducting material depends upon its low lyingfrontier molecular orbitals and the energy gap in between them. A new n-type organicsemiconductor-based on haxachloro-hexaazatrinaphthylene compound is reported. The electronicstructure and charge transport properties of the compound is calculated in the framework of densityfunctional theory (DFT). The electron-withdrawing group (-Cl) on the end position of the compoundcould help to lower the LUMO energy level and improve the air-stability and charge carrier mobility.The large electron affinity (2.60 eV) and low LUMO energy (-3.63 eV) suggests that the compoundswere to be air-stable and N-type organic semiconductor. Moreover, lower values of electron-injectionbarrier as compared to those of hole-injection barrier implied that the investigated compounds werebasically N-type semiconductors. The computed electronic coupling of LUMO of the compound was foundto be comparatively larger in the transverse-channel (86.6 meV) than other channels. The computedlarge electron and hole mobility was found to be 3.54 cm2V-1s-1 and 0.14 cm2V-1s-1. Further,hirshfeld analysis depicting the distribution of surface charge in between the molecular layers ofthe crystals revealed that the principal interactions were mostly due to the Cl…H/H…Cl andCl…Cl contacts of the compounds.

Mr SUBRAJEET ROUTImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Orissa

University of Agriculture and Technology, Bhubaneswar

Designation : Ph.D Research Scgolars

The Ichnocarpus Frutescens (IF) is a fiber yielding plant and having the longest natural fiber found ever, considering its length and strength the IF is very suitable for composite fabrication. However its body parts are usually used for the treatment of various diseases. Because of its medical and technological importance, the IF creates interest among the physicist, chemists, biologist, material scientist and technologist. So far our knowledge is concerned, there is no report on the X-ray structure of IF fiber. In this study X-ray structural investigation of cold plasma treated-modified fiber and untreated fiber are presented. The IF fiber was extracted from stem by treating with 4% dil. NaOH solution for a week. After alkali treatment the fiber was exposed to nitrogen (N2) cold plasma irradiation. It is an innovative approach for modifying the surface of IF fiber. The diffraction pattern of IF fiber are found to be cellulose-Iß with monoclinic structure in nature having lattice parameter a=7.784Å, b=8.201Å, c=10.380Å and full width half maxima (FWHM) = 96.55Å respectively. The (2 0 0) plane with an angle at 22.72° shows the highest intensity(Imax) peak of cellulose-Iß , normal diffraction pattern (fiber axis parallel to beam direction ). However, most of the peak intensity vary and number of peaks found to be missing when diffraction was carried out in a perpendicular mode (fiber axis perpendicular to beam direction) [6]; as shown in Fig. 1(a). The Imax peak, i.e. (2 0 0) plane become less intense as compared to (1 1 0) in the mounting. Again most of the missing peak become prominent and sharp after plasma treatment indicates the cold plasma induced crystallization. Also crystal size increases from 4.2644nm to 25.5123 nm and percentage of crystallinity (% C) also increase from 31.7% to 51.2% respectively. The decrease in its FWHM, azimuthal angle (?), helix angle (?) indicates the fiber orientation is enhanced. The details structural modified due to plasma treated has been discussed in the full paper.

Ms SURYAKANTI DEBATAImage Delegate ID Theme Details


Research


Institute of Technology (ISM) Dhanbad


Molecular electronics, of which the organic field effect transistors (OFETs), organic photovoltaics(OPVs) and organic light emitting diodes (OLEDs) linger as the three important divisions,essentially give credit to the ?-conjugated organic semiconductors (OSCs) for their notablecontribution in enhancing the device performance and economic convenience. OSCs are anticipated tobe the key ingredients for smart and flexible electronics in the future generation to come.Therefore, it is crucial to develop efficient materials to meet the current challenges in devicefabrication. Till date, an enormous attention has been put in the development of high-performingstable p-type materials and the hole transport mobility of p-type OSCs has reached up to anappreciably high value (~10 cm2V-1s-1). However, the development of ambipolar semiconductors isindeed necessary to improve the device performance through a balanced transportation of bothelectrons and holes. It requires the suitable positioning of both highest occupied molecular orbital(HOMO) and lowest unoccupied molecular orbital (LUMO) energy levels, along with the particularemphasis on the electron affinity (EA) and ionization potential (IP) values. The ambipolar behaviourin the small OSCs like oligoacenes, 6,13-bis(triisopropylsilylethynyl)pentacene andperylene-diimides can be introduced either by substituting halogens (i.e., -Cl and -F) and nitrogenin the pristine aromatic core or through molecular fusion by suitable linkers. In the same pursuit,we have designed a fused structure of two perylene-diimides through proper linking along the bayposition. The electronic property of the material has been studied through density functionaltheory, which revealed the suitable positioning of HOMO and LUMO of the material for realizingsmooth charge injection through Au-electrodes (work-function~ 5.1 eV). The low HOMO-LUMO gap and theadiabatic EA and IP values approaching 4 eV and 6 eV respectively suggest that the material displaysambipolar character.

Mr Vaanchhit VarshneyImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : DELHI

UNIVERSITYDesignation : STUDENT

Lithium ion (Li+) batteries have become striking for portable devices due to their high energydensity compared to other systems. With an increasing interest to develop rechargeable batteries forelectric vehicles, the lithium iron phosphate (LiFePO4) is considered to replace the currently usedLiCoO2 cathodes in lithium ion electrochemical cells [1,2]. LiFePO4 is a technically importantcathode material for new-generation power lithium ion battery applications because of its abundancein raw materials, environmental friendliness, perfect cycling performance, and safetycharacteristics. However, the commercial use of LiFePO4 cathode material has been partially hinderedby their low electronic conductivity. In order to improve the conductivity of LiFePO4, much efforthas been done [3,4]. However, coating by carbon is an efficient way to increase the electrochemicalperformance of these materials. Although, the carbon coating method obviously helps nothing in thelattice electronic conductivity or chemical diffusion coefficient of lithium within the crystal.Therefore, the substitutions at Li and Fe sites has been attempted by many researchers in order toimprove the conductivity [3]. It has been reported that Fe site doping weakens the Li–Ointeraction, resulting in high ionic mobility and diffusion ecoefficiency. Therefore, in this work,we have attempted to substitute cobalt at Fe site of LiFePO4 and checked the feasibility of doingfor Li ion Battery.

Mr Santanu MondalImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Aliah


Scholar

The stability of a three-body system is very popular topic of research for many branches of physicsin which mass and charge of the particles play the fundamental role. The very interesting situationarises when there exist bound three-body systems in absence of two-body subsystem under screenedCoulomb interaction between the particles. These states are known as Borromean states [1].Prediction of Borromean states of different three-body system have extensively done in differentliterature [2], whereas the availability of literature on the structural properties of those systemsin their borromean binding regime are scanty.We are mainly interested to explore the structuralproperties e.g. expectation value of kinetic and potential energy terms,radial and angularmoments,one-particle, two-particle, intracule densities, Coulomb holes, Pearson and statisticalangular correlation co-efficients,Fermi-contact term etc. of adiabatic H2+ molecular ion inborromean binding regime. These systems have applications in different aspects like astrophysical,nuclear physics, chemical science as well as frequently observed in laboratory plasma [3]. In theconference, rigorous calculations on different structural properties of H2+ will be presented. Theinterparticle interaction is considered as screened-Coulomb type. The calculations are done in theRitz variational framework using explicitly correlated Hylleraas type basis set and in the quadrupleprecision to ensure better numerical stability.

Dr Anirban BaguiImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : IIEST ShibpurDesignation : DST-INSPIRE

Faculty

The charge carrier mobility of polymer semiconductors is a crucial factor in determining the performance of organic electronic devices. In polymers, hopping is the principle method of charge transport. Here we have accurately determined hole mobility (µ) of PTB7, which is a widely investigated polymer having application in organic solar cells and transistors[1-2], by simple and powerful method of impedance spectroscopy.[3] To estimate the hole mobility of PTB7, ‘hole-only’ devices were constructed with structure - ITO/PEDOT:PSS/PTB7/Au. The impedance measurement was conducted using Agilent 4294A impedance analyzer.

Fig. 1.(a) Frequency dependence of Im Z at different voltages, and (b) Poole-Frenkel plot of mobility in PTB7 based ‘hole-only’ device (inset) as obtained from impedance measurements.

Fig. 1a shows normalized Im Z vs. frequency (f) curve at different bias voltages ranging from 3.6 to 6.8 V. The peak frequency (fp) shifts towards right with increase in applied bias. The transit time (?DC=0.42?p) of charges in the device is obtained from the resonance frequency (?p=1/fp). The hole mobility in the device is calculated by equation µ = d2/E?DC. Fig.1b describes the Poole-Frenkel plot of µ vs. E1/2 as obtained from impedance spectroscopy measurements of Fig. 1a. The zero-field mobility (µo) calculated from intercept is found to be 2.5×10-6 cm2V-1s-1. The charge carrier mobility in these devices are also estimated from dark I-V measurements using field dependent space charge limited current (SCLC) model - J/E2 = (9/8)(?o?r/d)?o exp (0.89?E1/2).[4] The value of µo thus obtained from SCLC method is found to closely match with that from the impedance measurement method.

References

1. Liang, Y.; Xu, Z.; Xia, J.; Tsai, S.; Wu, Y.; Li, G.; Ray, C.; Yu, L. Adv. Mater. 2010, 22, E135–E138 2. He, Z.; Zhong, C.; Su, S.; Xu, M.; Wu, H.; Cao, Y. Nat. Photonics 2012, 6, 591–595 3. Nguyen, N. D.; Schmeits, M.; Loebl, H. P. Phys. Rev. B 2007, 75, 075307 4. Goh, C.; Kline, R.J.; McGehee, M.D.; Kadnikova, E.N. and Fréchet, J.M.J. Appl. Phys. Lett. 2005, 86, 122110

Ms Annusha T LImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Nesamony memorial christian college,

marthandamDesignation : Msc, (PhD)

The synthesis of Au substituted ZnO nanocomposites material was achieved by using simple chemicalco-precipitation method. The gained Au –ZnO nano composite were subjected to variouscharacterization techniques like UV-Vis, FTIR, SEM, XRD and EDAX to discuss their optical,vibrational, morphological, structural properties.

Mr Ravi Kant VermaImage Delegate ID Theme Details


Research


LucknowDesignation : Ph.D. Student

Molybdenum disulfide is a member of transition metal dichalcogenides group. The two-dimensional molybdenum disulfide shows unique electrical and optical properties which are useful in opto-electronic applications. Here we study about recent progress in synthesis, properties, application and hetrostructures of two-dimensional molybdenum disulfide. Heterostructured materials show more functionality or flexibility in comparison to single component materials. Various synthesis techniques can be used to produce two-dimensional layers molybdenum disulfide with required properties according to application. Here we discuss different techniques of synthesis. We also highlight some challenges and opportunities in synthesis and application of two-dimensional molybdenum disulfide.

Mr GOURAB GIRIImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : INDIAN

INSTITUTE OF TECHNOLOGY INDORE

Designation : PhD(ongoing)

Elliptical galaxies are currently dragging huge attention of astronomers due to their peculiarbehavior hosted by them. They generally emit black-body radiation which is a very well-knownphenomenon, but a particular subclass of them show a huge outburst of energy in radio wavelength,called radio galaxies. After a lot of theoretical and observational studies, especially the recentdiscovery by Event Horizon Telescope, it is now confirmed that these galaxies are the constituent ofSuper Massive Black-holes (SMBH) influencing some strange AGN activities creating Kpc to Mpc scaledradio jets of hot magnetized plasma. More peculiarity adds when we see significant distortionoccurred in these large-scaled radio jets creating X-shaped radio galaxies. These galaxies are veryrare in the universe and prefer to stay in the low-density regions. They can be identified from thepresence of two double-lobed jet structure aligned at an angle to each other (wing and active lobe).Till date, there exists no single model which can explain all the properties of X-shaped radiogalaxies. Though, the Back-flow model and Merger model have gathered huge attention in describingthese galaxies. Back-flow model is based on the back-flowing of plasma and its evolution in atri-axial ambient medium whereas the merger model based on the accretion and/or merging of galaxiesleading to spin-flip of SMBH. Through our work, we have verified three major predictions of theBack-flow model with the power of state-of-the-art numerical simulation. Through high-resolution 2DRMHD runs using PLUTO code, we were able to check the wing formation mechanism, effect of magneticfield in its formation and the long-term particle/plasma evolution. The results are satisfactory andas predicted by the model. However, there exists some parametric restrictions under which this modelworks well. On a parallel note, we have tried to verify the fact, whether elliptical galaxies arethe left-overs of galaxy merging events or not. We have analyzed publicly available deep SDSS dataof nearby elliptical galaxies to find out the faint merger signatures resides with them usingunsharp masking and model subtraction. The result of our analysis strongly indicates that ellipticalgalaxies are indeed the remnants of past galaxy collisions and are still actively evolving throughgalaxy merging events. But if this result supports merger model theory of X-shaped radio galaxyformation, then also the low availability of these galaxies is imposing questions on this model’svalidation itself.

Ms MONALISA HALDERImage Delegate ID Theme Details


Research


INSTITUTE OF TECHNOLOGY DURGAPUR


Abstract: Background: Fossil fuels are a leading source of global warming pollution. Even the waste products are hazardous to public health and the environment. Considering the business cost and environmental concerns, the technology of ‘Bio-waste-to-Energy’ is recognized as an increasingly important renewable source of energy. Recent researches show that up to 68% of household waste is biodegradable and can be used as energy material [1]. In India, a large amount of tea-wastage is produced in daily basis. According to the Assocham report released in December, 2011, as the world's largest consumer of tea, India uses nearly 30 percent of the global output. Tea-wastages are usually disposed by burning or by deposition in landfills that cause environmental harms. In this situation, conversion of tea-wastage to an environment-friendly higher value product such as porous activated carbon (AC) would be more preferable. The as-obtained porous AC is served as electrode material, super-capacitors,solar energy adsorbent [1]. The magnificent properties of AC makes it suitable candidate for high-performance polymer composites. The fabrication of flexible polymer based dielectrics with AC as filler element is very much desirable in the applications related to microwave absorbing property, charge/energy storage devices.

Experimental Method: Here we have produced KOH activated micro porous carbon from tea wastage. We have fabricated flexible Polyvinyl alcohol (PVA: easily processable, cheap and eco-friendly polymer) based films using Activated Carbon (AC) as nanofiller with different weight percentage. Electrical (AC, DC) characterizations of the films are done to study their prospect as the dielectric materials in energy storage, microwave absorption applications.

Results: Frequency dependent total measured conductivity of the sample has been studied in between 20 Hz – 2 MHz frequency range at different temperatures. It shows relevant charge storing capacity which is very beneficial as energy material. Measured conductivity increases with temperature as well as with frequency.

Conclusion: Depending upon the results, we can apply the Activated Carbon (AC) based polyvinyl alcohol (PVA) dielectric film to make flexible, environmental friendly energy/storage devices, microwave absorbents. References: Peng, C; Yan, X. B.; Wang, R. T; Lang, J. W; Ou, Y. J.; Xue, Q. J., Electrochimica Acta 2013, 87, 401-408.

Mr RAKUMAR DEYImage Delegate ID Theme Details


Research



Research Fellow

DLC is amorphous carbon structure with different amounts of the sp3 and sp2 hybridized carbon bounds [1,2]. Boron-doped diamond-carbon (B-DLC) thin film shows much attention in photovoltaic and solar cells applications in the last few decades. Doping of diamond films have been a challenging affair to the scientists for their fruitful exploitation in high temperature electronic device and solar cell applications. In this study, DLC films were doped with boron by using Pulsed Laser Deposition (PLD) technique. A Nd:YAG laser (wavelength (?)= 355 nm, duration of pulse t=10 ns, frequency f=10 Hz) was utilized to ablate the targets. Vitreous carbon disc was ablated to deposit diamond-like carbon (DLC) films. The films are identified by using FESEM, XPS and Raman measurements. Hot-probe study indicates the films to be p-type. Core level XPS spectra of B1s are located at~189.5 eV and indicated that boron atoms are in the B-C network. Raman studies indicated that incorporation of boron in DLC matrix rendered the host lattice to dilate favouring graphitization. Increase in FWHM of the G-peak is observed for films deposited with higher amount of boron. Undoped DLC films shows band gaps ~2.1 eV. Band gap value decreases from 2.1 eV to 1.85 eV with the incorporation of boron. A cell structure: glass/ITO/B:DLC/ZnO/Ag was conceived. This I-V characteristic is recorded under ~100 mW/cm2 illumination. Non-rationalized layer thicknesses constituted the above cell structure. An open circuit voltage (VOC) ~110 mV, short circuit current density (JSC) ~7.5 mA/cm2 and fill factor (FF)~0.3 are recorded for the cell. However, the recorded conversion (?) efficiency ~0.23% is quite low. Ideality factor and built in voltage of the above structure showing PV characteristic are 2.23 and 0.19 eV, respectively. Activated carrier density (NA) is found to be ~2x1018 cm-3. Successful incorporation of boron in DLC films was accomplished by sequentially ablating boron during the synthesis of DLC for obtaining B:DLC films. A cell structure: glass/ITO/B:DLC/ZnO/Ag was conceived successfully. References: 1. Robertson, J. Mater. Sci. Eng. R Rep. 2007, 37(4–6), 129-281. 2. Písa?ík, P.; Mikšovský, J.; Remsa, J.; Zemek, J.; Tolde, Z.; Jelínek, M. Applied Physics A 2018, 124(1), 85(2-9).

Dr Chandrabhan DohareImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : School of Physical Sciences, JNU


Abstract: Two dimensional transition metal dichalcogeniges (TMDs) are of a great interest to thescientific community due to its potential for applications in electronics, optoelectronics andsensing. In particular, sulfides and selenides of molybdenum (Mo) have attracted interest as theypossess a band gap, which is important for integration into electronics device structures. Thus, ascalable method is required to fully explore their exceptional optical and electronic properties.Here we report (1) the synthesis of thin films of MoS2 and MoSe2 using chemical vapor deposition and(2) study of exciton in bilayer and trilayer MoS2, MoSe2 samples using absorption and ellipsometricspectroscopies. Highly homogeneous TMD films are produced over desired areas, by modifying thethickness of pre-deposited metal layer. The formation of MoS2 and MoSe2 thin films were confirmed byX-ray diffraction, UV-visible absorption spectroscopy, Raman spectroscopy, atomic force microscopyand spectroscopic ellipsometry. Systematic trends are observed for band gaps, transition energiesand for exciton binding energies of MoS2 and MoSe2. The thickness dependent band gap for MoS2 /MoSe2changes from 1.55eV/1.02eV to 1.64eV/1.2eVas one move from trilayer to bilayer, respectively. Theseoptical transitions herein reported enhance our understanding of TMDs and thus provides informativeguidelines for MoS2 and MoSe2 based optical device designs.

Mr Bhaskar BiswasImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : university of

kalyaniDesignation : research

Scholar

Abstract: The magnetocaloric effect (MCE) is characterized by a magnetic-entropy/adiabatic-temperature change and the occurrence of the MCE happens under the influence of a changing applied magnetic field on a ferromagnetic material. This means that the effect reaches its maximum in the vicinity of magnetic phase transition points. Few recent studies on manganites viz., La0.7Ca0.3MnO3, La0.62Gd0.05Ca0.33MnO3, La0.87Sr0.13MnO3 etc.[1], reported to show large MCE at intermediate or high magnetic field only. Therefore, the challenge remains to find out new materials that exhibit a large MCE at low magnetic field. The guideline for the choice of an appropriate material having large MCE is that it should have sharp ferromagnetic (FM) to paramagnetic (PM) phase transition. In manganites, recently ultra-shrap magnetization (M) steps have been reported at low temperature below 50K in Pr, Y, Ce based system substituted with other cations at rare earth and Mn-site [2]. In view of the fact, in the present study, a detailed investigation of the structural and magnetic properties of phase-separated Li-doped Pr1-xLixMnO3 manganites system is done. Rietveld analysis of the XRD data of the samples has been done using Maud software. Temperature and magnetic filed dependent magnetization has been measured using ‘Vibrating sample magnetometer’ and the data is used to analyze MCE of the present sample.

References: 1.M.H.Phan et al.,J.Magn.Magn.Mater.308.325 (2007) and references therein 2.K.R.Mavani et al.,Physical.Rev.B72,104421(2005)

Mr JAYJIT KUMAR DEYImage Delegate ID Theme Details


Research


Association for the Cultivation of Science


The concept of using synchrotron radiation source to characterize the atoms or molecules is actually a revolutionary attempt in the field of crystallography. The most important advantage of synchrotron radiation over a laboratory X-ray source is its brilliance (both the brightness and the angular spread of the beam). Additionally, Its high energy, small wavelength, coherent and/or polarized beams makes it superior over the lab based X-ray source. So analysis of the synchrotron diffraction studies will provide the important information about the microscopic atomic order or disorder in the spinel structure. This study will help us to determine the driving factor of exotic low temperature properties such as Verway transition, magnetic ground state correlated to the short-range order in the octahedral sites of the spinel structure, and occurrence of ferroelectric order. Over the last few decades significant amount of works have been performed on the cubic spinel compounds focusing on different fundamental issues. In order to probe the origin of the physical properties, the detailed structural properties of any compounds need to be explored. Here, we have analyzed the unexplored low-temperature structural instability of NiFe2O4 and ZnFe2O4. We report a ferroelectric order at ~ 110 K for ZnFe2O4 and ~ 98 K for NiFe2O4, which carries a normal spinel structure and an inverse spinel structure respectively with a centrosymmetric Fd-3m structure at room temperature. The value of spontaneous electric polarization is considerably high as ~ 160 ?C/m2 and ~ 0.29 ?C/cm2 at 5 kV/cm poling field for ZnFe2O4 and NiFe2O4 respectively. For NiFe2O4 ,the synchrotron diffraction studies confirm a structural transition at ~ 98 K to a polar non-centrosymmetric structure of P4122 space group while for ZnFe2O4, it goes to the polar non-centro symmetric trigonal space group R3m at ~ 110 K. The occurrence of polar order is associated with an ordered occupancy of Ni/Zn and Fe atoms at the octahedral sites of the P4122 and R3m structure, instead of random occupancies at the octahedral site. The results propose that ZnFe2O4 and NiFe2O4 both are the member in the type-II multiferroics.

Mr REJJAK LASKARImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : ALIAH

UNIVERSITYDesignation :

JRF(DHESTBT,GOV OF WB)

: We present a semi-classical theory of interaction of a three-level V-type atomic system (87Rbatoms) with two linearly polarized lights in which the atom is treated as a quantum three-levelsystem and the light fields are considered classically. Using density matrix perturbation theory,analytical expressions of linear and nonlinear susceptibilities are derived for stationary as wellas for moving atoms. Variation of first order (linear), third and fifth-order (nonlinear)susceptibilities w.r.t. frequency and intensity of coupling field is analyzed. It is found thatenhanced self-Kerr nonlinearity can be achieved under two photon resonance conditions where the Kerrnonlinearity of the medium is modified and greatly enhanced in the spectral region ofelectromagnetically induced transparency (EIT) window under strong coupling field. Influences ofcoupling field intensity and Doppler broadening of the medium on self-Kerr coefficient (second orderintensity dependent refractive index) and fourth order intensity dependent refractive index areinvestigated. The strong coupling laser creates dressed states between optically forbidden (underdipole approximation) hyperfine levels in 87Rb atom. We study the position of dressed eigenstates ofthe total Hamiltonian of the atom-light system which can explain the formation of EIT and relatedenhanced self-Kerr nonlinearity.

Dr KULATHURAAN KImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Arulmigu

Palaniandavar College of Arts and Culture


In this paper, we report the effect of electrochemical etching time on the morphological,structural, optical and electrical properties of porous silicon (PS) synthesized by electrochemicalanodization of p-type silicon at current density of 100 mA/cm2. Atomic force microscopy (AFM)measurements showed that the square root of roughness is increased with etching time. Scanningelectron microscope (SEM) investigations revealed that the microstructure of porous silicon isvarying with etching time. The cross sectional view of images also indicated that average porediameter and thickness increasing with increase etching times. Similar trend is noticed on theintensity of the PL emission band in the red light region. The X-ray diffraction pattern of the PSconfirm the porous silicon at 2? = 69.14°. The FTIR shows the Si-H2 and Si-O-Si vibrations in thefabricated samples. Current-Voltage (I-V) characteristics of fabricated Al/PS/c-Si/Al junctionsprepared at different etching times are investigated and analyzed. The ideality factor, saturationcurrent density and barrier height of porous silicon junctions were strongly found to be dependenton the etching time.

Mr KALYAN BANERJEEImage Delegate ID Theme Details


Research



Scholar

Effect of Cholesterol on the interaction of sodium chloride with phospholipid membrane

Kalyan Kumar Banerjee, Pabitra Maity and Sanat Karmakar* Soft matter and Biophysics Lab, Department of Physics Jadavpur University,KOL-700032 Email: [email protected]

Cholesterol is an essential and important component in all eukaryotic cell membrane. The structure and functions of membranes are greatly influenced by cholesterol. Therefore, effect of cholesterol on the ion-membrane interaction have drawn significant attention in biophysical study. We have systematically investigated the interaction of sodium salt with phospholipid membranes in both fluid and gel phases using dynamic light scattering (DLS), zeta potential and isothermal titration calorimetry (ITC). We have prepared vesicles with DMPC and DPPC in order to access both gel and fluid phases. We have obtained large binding constant(Na+ ) in gel phase of DMPC compared to fluid phase. Interestingly, the binding constant in fluid phase of DMPC (9.64 M-1) was found to be greater than fluid phase of DOPC (0.44 M-1), which suggests that chain saturation affects the Na + binding to the membrane. Ternary mixtures composed of DMPC, DOPC and various concentrations of cholesterol and binary DMPC-cholesterol mixture were studied in order to gain insights into the effect of ions on the formation and structure of cholesterol-rich domains, called rafts. None of these systems show any significant change in the heat flow when vesicles are titrated with sodium salt. From DLS and zeta potential analysis we get that for mixture of DMPC, DOPC+cholesterol, DOPC+DOPG+cholesterol with ion(NaCl) zeta potential increases with the increase of ion concentration and it is also true for different concentration of cholesterol and this is possibly supporting increase in Na+ binding with the lipid-cholesterol structure.

Ms KAVYASHREE .Image Delegate ID Theme Details


Research

Category : PhysicsOrganisation : MNNIT

ALLAHABAD, PRAYAGRAJDesignation : Research

scholar

Today’s world is a fast-growing platform for technologies, which increases the need for energy consumptions. There are conventional and non- conventional ways for producing the energies, but the storage of energies is again the primary issue. The electrochemical energy storage, which is usually known as the supercapacitor, gains a potential interest due to its both energy and power densities, and its cycling retention. Here, we synthesized, tuberose structured Sr(OH)2 and flakes covered tuberose structured Cu doped Sr(OH)2 thin films using the cost-effective successive ion layer adsorption and reaction (SILAR) technique. X-ray diffraction analysis reveals the polycrystalline nature of the film with an orthorhombic crystal structure. The supercapacitive properties were studied using cyclic voltammetry, galvanostatic charge-discharge, and electrochemical impedance spectroscopy. It has been perceived that doping clearly increases the supercapacitive behavior. The surface morphology plays a significant role in the performance of supercapacitive properties. Fractal analysis is an analytical tool that can extract more information about the surface differently from the traditional analysis. The surface morphology has been studied using the field emission scanning electron microscopy (FESEM). The surface roughness analysis has been done qualitatively using FESEM micrographs, and further, the morphology has been examined by fractal analysis. The effect of doping on the surface evolution of thin film was investigated by fractal analysis. Thus we have developed a linkage between fractal analysis and supercapacitive properties.

Ms Pooja KarmaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : School of

Instrumentation Devi Ahilya Vishwavidhyalaya Indore

Designation : PhD student

Bandgap engineering and surface nano structuring of TiO2 thin films play a crucial role in increasing its efficiency to get utilized in fabrication of sensors, optoelectronic devices and in various spintronic applications.[1-2] Precise control over the defects is needed to modify the binding energy of O-2p and Ti-3d states which can bring the change in bandgap and enhance the photocatalytic activity of these thin films.[3] Ion irradiation modify the structural and electronic properties of Cr-doped TiO2 prepeared by RF sputtering.[2] In the present work, we are going to tailor the material properties by Cr-doped TiO2 prepared by pulsed laser deposition and modify its properties using swift heavy ion irradiation with different ions. The films were irradiated with 100 MeV Au and Si ion beams at different fluences ranging from 5X1012 ions/cm2 to 1X1013 ions/cm2. Structural characterization shows that as-deposited films were amorphous in nature and no phase change has been observed with increasing ion fluence rather successive amorphization of the films as confirmed by angle dispersive X-Ray diffraction technique. Field emission scanning electron microscopy (FESEM) images shows the agglomeration and reveals the localized defects caused by two swift heavy ions of different masses which appear as segregated clusters over the surface of thin film. Atomic Force Microscopy (AFM) also depicts the segregation over the surface and increment in the roughness after ion irradiation. UV visible studies shows the variation in band gap energy as the consequence of formation of various sub band-gap energy states due to accumulation of oxygen vacancies near the Fermi edge. Core level photoelectron spectroscopic studies also reveals broadening and shifting of Cr peaks towards higher energy as compared to Au ion irradiated thin films. In Both the Cases, spectra exhibit typical O 2s and Ti 3d structure between 4 and 10 eV. The additional states appear near fermi edge is originated from Ti 3d states related to oxygen vacancies and the peak at about 3 eV is attributed Cr 3d states due to doping.Detailed electronic structure will be correlated with its optical properties will be discussed.

References 1. S.K.Zheng,T.M.Wang,G.Xiang,C.Wang,Vacuum 62 (2001)361. 2. Sagar Sen, Ajay Gupta, D.M.Phase, Ratnesh Gupta, Applied Surface Science 440 (2018) 403. 3. C. P. Cheney, P. Vilmercati, E.W. Martin, M. Chiodi, L. Gavioli, M. Regmi, G. Eres, T. A. Callcott, H. H. Weitering, and N. Mannella, Phys. Rev. Lett. 112 (2014) 036404.

Dr Homnath LuitelImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : HRDD

Designation : Assistant Proffessor

Ab initio calculations under the frame work of density functional theory has been applied tocalculate magnetic properties in different p-block elements doped semiconducting oxides (viz., ZnO,TiO2, SnO2). Most of the p-block elements when doped at anion site produces a significant magneticmoment in the non-magnetic semiconducting oxides. The p-orbital electrons of the dopant is theprimary source magnetism. The anomaly of ferromagnetic and anti-ferromagnetic spin ordering inmagnetic system has been understood by detailed spin-spin interaction study. Two dopants were dopedat different oxygen sites at two different doping distances. For each case, ground state energy foreach spin-ordered system has been calculated. The spin ordered system with less ground state energyis taken as a stable spin ordering.

Dr Narayan BeheraImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Institute for

Plasma Research, Gandhinagar

Designation : Postdoctoral Fellow

The interaction of laser-produced plasma with the external magnetic field has been widely studiedusing permanent bar magnets. But it is not possible to capture the plume images along the magneticfield lines using this configuration, which is necessary to understand the three-dimensionalstructure of the expanding plume across the magnetic field. We have resolved this problem byreplacing the permanent bar magnets with a specially developed Helmholtz coil which allows plumeimaging both along and across the magnetic field lines. Two internally synchronized ICCD cameras,mounted in a direction orthogonal to the plume propagation has been used to capture images of theexpanding plasma plume along and across magnetic field lines. An Nd:YAG laser (wavelength = 1064 nm,pulse width = 8 ns) has been used to produce plasma plume in the presence of transverse uniformmagnetic field, varying from 0 to 0.57 T. This imaging technique helps to understand and discovervarious time and field-dependent features like, diamagnetic cavity, magnetic striations, plumespiting, plume bifurcation etc. 3D structures of the diamagnetic cavity and expanding plasma plumehave also been obtained using this imaging method. Subsequently, various newly developed imageprocessing techniques and models have been used to explain observed complex features of expandingplasma plume in the magnetic field. Details of developed techniques and physics involved in theobserved features will be discussed.

Dr Vivek TalwarImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : I K Gujral

Punjab Technical University, Kapurthala

Designation : Assistant Registrar

Graphene has been a promising material for scientific community in recent years for next generationdevices and materials. Polyaniline (PANI) based nanostructures like nanofibers, nanowires andnanotubes also found their employment in electro-chromic devices, solar cells, sensors, separators,photovoltaic cells and anti-corrosion coatings. The synthesis of Graphene/PANI composites has beendone through oxidation of aniline with rapid mixing method in the presence of Reduced graphene oxide(rGO), which was prepared using modified hummers method from fine commercial graphite powder..Further these composites were characterized by X-ray diffraction (XRD) and IR spectroscopy whereastheir morphological studies were done with Scanning Electron microscopy (SEM) and TransmissionElectron Microscopy (TEM). The results revealed the synthesis of G-PANI nanocomposites and graphenenanostructures in between PANI sheets.

Dr MD MABUD HossainImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Aliah


Professor

Abstract: Saturated absorption spectroscopy (SAS) is widely used in laser spectroscopy of atomic andmolecular transitions. In SAS, counter-propagating weak probe and strong pump laser beams whichoriginated from a source laser beam pass through a vapour cell and overlap inside the cell. OppositeDoppler shifts and saturation by the pump beam allow the observation of Doppler-free and narrowpeaks in the probe absorption which finds applications in realization of frequency references. Inthis work, we study the effect of external homogenous magnetic field on the SAS spectra formed bythe polarization pump-probe laser spectroscopy in Rb vapour cell. The Rb cell is placed in aHelmholtz coil setup with longitudinal direction and the pump-probe laser lights are to be set assome definite circular/pi polarization. In this case, the external magnetic field produces Zeemansublevels of the hyperfine transitions of Rb D2 line, and experimentally the pump-probe laserfrequency is tuned around the D2 line of the Rb atoms. Depending upon the various polarizations ofthe pump-probe laser fields, we observe various type of SAS spectrum which shows transition inZeeman sublevels. The strength of the various peaks in the SAS spectra is used for the explanationof the optical pumping effect in the Zeeman sublevels. In addition, the variation of externalmagnetic field is also studied to measure the splitting of Zeeman sublevels of the Rb hyperfinetransitions. This experimental study will help us to know the atomic transition rates in the Zeemansublevels, and at the same time, the SAS spectrum of the Zeeman sublevels is to be used for precisefrequency locking of external cavity diode laser for various experiments in nonlinear laserspectroscopy.

Mr Neeraj SharmaImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Jamia Millia

IslamiaDesignation : Ph.D. Scholar

The green approach to develop a functionalized graphene derivative as an effective flame retardant.The functionalized graphene oxide was synthesized by introducing nitrogen-supported phosphorusfunctional groups on the surface of graphene derivative via solvent, which is prepared by thetreatment of sodium dihydrogen orthophosphate and choline chloride. Subsequently, the resultantmaterial is characterized by, X-ray diffraction, Raman spectroscopy, Thermogravimetric analysis, andscanning electron microscopy. The as-prepared functionalized graphene oxide solution coated clothpiece was sustaining its initial shape and size by releasing a little amount of smoke at the earlystage without catching fire for more than 100s, whereas the pristine cloth is totally burned outwithin 10 s, leaving small amounts of black mass. This simple method of directly functionalizedgraphene oxide surface can be a common process for the cost-effective bulk production of ananocarbon template for extremely high effectiveness, nontoxic flame-retardant applications.

Mr Shashank SinghImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Panjab

UniversityDesignation : PhD Student

Particle Induced X-ray Emission technique (PIXE) is a well-established accelerator-based technique.PIXE is used for the elemental concentration determination of the elements ranges from 13 ? Z ? 92.In the present study, the elemental concentrations of the Hay powder (IAEA-V-10) and Milk Powder(IAEA-153) were determined with the help of the PIXE technique. This study will be focused on tofind the detection limit and sensitivity of the PIXE for the biological and botanical samples. Table1. shows the concentration of the elements (part per million (ppm) range) for the IAEA-V-10 andIAEA-153 reference samples. Fig. 1: shows typical PIXE spectra of IAEA-V-10 reference samples.Totally 17 elements namely P, K, Ca, Sc, Cr, Mn, Fe, Co, Ni, Cu, Zn, Se, Br, Rb, Y, Ga and Se wereidentified with the help of PIXE technique in IAEA reference samples.

Dr Arun SinghImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Jamia Millia

IslamiaDesignation : Assistant

Professor

The Present work reports a chemiresistive sensor for chlorine (Cl2) gas in the range of 2–200 ppmbased on nickel oxide (NiO) nanoparticles obtained by wet chemical synthesis. The nanoparticles werecharacterized by x-ray diffraction (XRD) analysis, ?eld-emission scanning electron microscopy(FE-SEM), thermogravimetric analysis (TGA), transmission electron microscopy (TEM),Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, ultraviolet-visible (UV–Vis)spectroscopy, and photoluminescence (PL) spectroscopy. XRD spectra of the sensing layer revealed thecubic phase of NiO nanoparticles. The NiO nanoparticle size was calculated to be ~21 nm using aWilliamson-Hall plot. The bandgap of the NiO nanoparticles was found to be 3.13 eV using Tauc plotsof the absorbance curve. Fast response time (12 s) and optimum recovery time (~27 s) were observedfor 10 ppm Cl2 gas at a moderate temperature of 200oC. These results demonstrate the potentialapplication of NiO nanoparticles for the fabrication of highly sensitive and selective sensors forCl2 gas.

Mr SHAKTI RAYImage Delegate ID Theme Details


Research


Institute of Technology - Indian School of Mines,

DhanbadDesignation : Research

scholar

To withstand the future energy crises, researchers around the globe are looking for an alternativerenewable clean source of energy because the natural energy resources are depleting day by day dueto rapid growth of industrialization. In this context, hydrogen can be considered as the future fuelsource because of its high energy density, light weight and non-polluting behaviour. However,storing the hydrogen gas in ambient environment has been a major challenge. Tremendous effort hasbeen devoted to research and development of the material that can hold sufficient hydrogen in termsof gravimetric and volumetric densities and achieve the target set by US Department of Energy (5.0wt % and > 40 kg/m3 by 2020). Of many proposed materials for hydrogen storage, boron basednanoclusters are considered as a class of promising materials for efficient hydrogen storage. Thehydrogen adsorption in Sc doped small boron cages (BnSc2, n=6-10) were investigated within theframework of density functional theory. The complexes B6Sc2, B7Sc2, and B8Sc2 are found to adsorbingup to 8H2 molecules giving rise to comparatively high gravimetric densities of 9.43 wt %, 8.87 wt%,and 8.37 wt% respectively which is quite remarkable in accordance with the target set by US DOE. Theaverage adsorption energies were found in the range of 0.08-0.19 eV/H2 inferring physisorptionprocess, and the fact is also supported by the average distance from Sc to H2 molecules which was inthe range of 2.13Å-2.60 Å. In addition, the range of adsorption energies and elongation in H-Hbond length bespoke the fact that the hydrogen molecules were adsorbed via Kubas interactions. ADMPmolecular dynamics simulations study at different temperatures such as 0K, 30K, 70K, 200K, and 300Krevealed that for B6Sc2 to B9Sc2 up to 3H2 were attached to the metal centres at all the consideredtemperatures.

Mr NITU SINGHImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Maulana Azad

National Institute of Technology, Bhopal

Designation : Pd.D. Scholar

In this study, the effect of Sn doped on the structural, optical, morphology and gas sensingproperties of WO3 nanostructures has been discussed. Pure and Sn (0.5 to 2.0wt%) doped WO3 materialwere synthesized by chemical co-precipitation route. X-ray diffraction (XRD) analyses confirm thatthe prepared material is polycrystalline WO3, orthorhombic structure with crystallite size in therange 30.50 - 22.71nm. The UV-visible absorption demonstrates a decrease in the energy band gap(2.57eV – 2.42eV) with an increase in the Sn doping concentration and optical property of Sn dopedWO3 have been find out by photoluminescence (PL) spectroscopy. The gas sensing measurements wereperformed on pure and Sn doped WO3 nanostructures to select dopant concentration at roomtemperature. The sensor optimized with Sn 1.0 wt% doping has been found to be high (96.98%) sensorresponse at NH3 200ppm gas concentration. The WO3 nanostructure-based gas sensor exhibits highsensitivity for ammonia as well as quick response at low temperature.

Mr Nandan GhoraiImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Institute of

Nano Science and TechnologyDesignation : PhD Student

Heavily-doped semiconductor nanocrystals (NCs) exhibit localized surface plasmon resonance (LSPR) ininfrared region (IR). Recently, tunable nature of LSPR in IR region has been gaining increasingattention due to their unique opto-electronic properties. Here. Two different type ofnon-stoichiometric Cu2-xS Nanocrystals (NCs) have been synthesized by hot injection method bychanging the composition of the copper and sulphur. Optical studies confirmed that there is welldefined localized surface plasmon resonance (LSPR) absorption from visible to mid-infrared region ofthe spectrum. We have employed transient ultrafast pump-probe spectroscopy to understand carrierthermalisation dynamics and heat dissipation in Cu2-xS NCs. At low pump power fluency, hole-phononrelaxation time constant has been found to be in the range of 240-440 fs for Cu2-xS NCs dependingupon pump wavelengths (400 nm, 800 nm). Hole-phonon coupling constant (G) have been estimated fromtransient absorption data and it is in the range (1.6-2.7) x1010 JK-1s-1cm-3 for Cu2-xS NCs atdifferent excitation wavelengths which is one order less than metallic system. Also, we havesuggested a new mechanistic scheme for carrier thermalisation dynamics, in accordance withtwo-temperature model (TTL) as reported in literature for metallic plasmon dynamics.

Mr Bakul DasImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Cooch Behar

Panchan Barma UniversityDesignation : Ph.D research

scholar

We monitor Very Low Frequency (VLF) radio signal using a well-designed receiving system in EasternIndia at Cooch Behar [26.3340N; 89.3260E]. We use a call sign CHB for our receiving station. The VLFsignals transmitted from different navy transmitters e.g. VTX [8.4330N; 77.7330E], NWC [21.8160S;114.1650E], JJI [32.0820N; 130.8270E] around the world are received by an E-field whip antenna.Signals are amplified twice by a preamplifier consists of two LF356 JFET input low noise operationalamplifier and inbuilt sound card of a computer which records the amplitude of the pre-amplifiedsignals at the rate of 4 data points per second. Spectrum Lab data logging software is used for thispurpose. Several Earthquake events have taken place during our observation period. Differentanalysis methods like SRT-SST, DLPT-DLDT, Standard Deviation Test, Night Time Fluctuation etc. havebeen used earlier by different group of scientists around the world to study Ionospheric anomaliesduring earthquake. We used here wavelet analysis for better clarity of the study to find VLF signaldisturbances due to seismic activity. Wavelet power spectrum and scale averaged power have beenchecked for several earthquake events and found very promising results. Presence of other naturallyoccurring events like lightning, Magnetic storms etc. also are checked to ensure that changes in VLFsignal amplitude or Ionosphere are only due to seismic activity.

Dr Raghvendra PandeyImage Delegate ID Theme Details


Research


DelhiDesignation : Assistant

Professor

Oxide ion conductors have gained much attention in recent years due to their technologicalapplication as electrolytes for solid oxide fuel cells (SOFCs), oxygen sensors, oxygen separationmembranes and as a catalyst material. To date, several systems of fast oxide ion conductors havebeen reported including fluorite-like systems, perovskite-based Sr and Mg incorporated LaGaO3system, silicon and germanium apatites, La2Mo2O9 (LAMOX) materials, BIMIVOX family derivatives, andsome complex oxides. SOFCs are highly efficient devices that convert chemical energy into electricalenergy and require electrolyte material with specific properties. A good SOFC electrolyte mustexhibit negligible electron conductivity, high oxide ion transport, and stability in both oxidizingand reducing atmospheres, as it is sandwiched within the anode and cathode sides of the fuel cell.The study on SOFCs with lower operating temperatures and higher energy efficiency has inspired thediscovery of new oxide-ion conductors and improved the understanding of oxide-ion diffusionmechanisms. Although there exists a variety of structure types in hexagonal perovskite-relatedmaterials, oxide-ion conductors are quite less. In the present work, we have synthesized thehexagonal perovskite-based Ba3MoNbO8.5 system via solid-state reaction route1 and investigated thestructural, microstructural and most importantly electrochemical properties for suitability of it asa solid electrolyte for IT-SOFC.

Mr Karunesh Kumar MishraImage Delegate ID Theme Details


Research

Category : PhysicsOrganisation : Banaras

Hindu UniversityDesignation : Research

Scholar

Cramer – Rao bound and the quantum Fisher information are figure of merit for quantuminterferometric phase sensitivity. We study the phase sensitivity by a Mach-Zehnder interferometer(MZI) by injecting different type of superpose coherent states and in both input port. We calculatethe phase sensitivity with the intensity difference as well as single- mode intensity measurementscheme. We perform these methods in three layouts. In first, we inject light beam in coherent states on both input port of MZI. In the second, we inject light beam in coherent state on one inputport and Schrodinger cat state on second state. In last scenario, we inject light beam in coherentstates on one input port and superposition of coherent state with pi/2 out of phase on other inputport of MZI. We compare the phase sensitivity of MZI under these different scenarios.

Dr Dinesh TripathiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : King George's

Medical UniversityDesignation : Research

Associate

Dinesh Tripathi1*, Sunita Tiwari1, Sandeep Bhattacharya1, Chetna Mishra2 1Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh, India 2Department of Biochemistry, King George’s Medical University, Lucknow, Uttar Pradesh, India [email protected]

Background: Cell death following ischemia brain injury leads to life threatening problem to patients. Recent studies have shown that autophagy plays a key role in ischemic neuronal death, and treatments that target autophagy may represent a novel strategy in neuroprotection. Objectives: The present study investigated the protective effects of Amla fruit extract on autophagy and mitochondrial dysfunction following in vivo ischemic stroke, and discuss the underlying mechanisms. Methods: A rat model of middle cerebral artery occlusion (MCAO) was constructed to induce ischemic stroke. Rats were orally administered Amla fruit extract post induction of ischemia. Brain damage due to cerebral ischemia was assessed by oxidative stress marker malondialdehyde (MDA), GSH and apoptotic population by flow cytometry under in vivo ischemic conditions. Mitochondrial complexes and mitochondrial bioenergetics are also measured to evaluate the mitochondrial dysfunction. These changes were further assessed by analysing the expressions of autophagy-related proteins (beclin-1, LC3), and mitophagy-related proteins (BNIP3 and cytochrome C) were evaluated by western blotting. Results: The results showed that Amla fruit extract significantly decreased the apoptotic cells following an in vivo ischemic stroke. Meanwhile, treatment with amla fruit extract retained serum GSH levels and led to a lower MDA level. Amla fruit extract modulates mitochondrial complexes after MCAO and also significantly restored the mitochondrial bioenergetics. However, amla fruit extract significantly ameliorated the protein expression of beclin-1 and BNIP3, the LC3-II to LC3-I ratio, and the release of cytochrome C from mitochondria to cytoplasm. Conclusion: These findings provide new insights that amla extract has a therapeutic effect in ischemia-induced autophagy and mitochondrial damage and thus can help in defining better therapy against ischemic stroke.

Dr Santhosh Kumar J UImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Chulalongkorn

UniversityDesignation : Postdoctoral

Fellow

Medicinal plants and their products, since time immemorial, have been used in virtually all culturesas a source of medicine. In India, a number of plant species are used as a medicine, and in recentyears, the trade in medicinal plants has increased several folds. However, with increasing demandfor, and a burgeoning trade in, raw herbal products, there has been concern over the safety and theefficacy of the herbal products. Recently studies shown DNA barcoding provides a definitive means ofauthentication and found adulterant or substitute. We have developed comprehensive HerbalAuthentication System (HAS). The HAS database focuses on developing a digital key that would enableeasy identification of the medicinal plants and its products. It integrates the floristic details,trade, a drug database, and DNA barcoding information. End user search can be by plant name or drugname in order to get the complete details. It provides information about Genes, Sequences, GenBankaccession numbers, Herbarium details and images, raw drug repository details. Presently thisdatabase contains details for nearly 250 highly traded medicinal plant species. This work provides acentralized medicinal materials DNA barcode database for sequence data, details of species,analysis, and exchange for promoting the identification of medicinal materials. This, when completewill be the first of its kind in the country and this HAS, can be used as an aid in regulating rawherbal trade in the country.

Dr GURPREET SINGHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : LYALLPUR

KHALSA COLLEGE,Designation : ASSISTANT

PROFESSO

Besides increasing the crop productivity, various fungicides are known to cause variation inphysiological and metabolic profiling. The present study analyzes the effect of different fungicides(Carbendazim) on glucose-6-phosphate dehydrogenase (G6PDH) enzyme in the developing seedlings ofchickpea. Sequences from the chickpea genome were retrieved from genome database using G6PDH genefrom Arabidopsis as standard, these sequences were aligned and phylogenetic analysis was carriedout. We observed that chickpea have four genes varying in amino-acid length and sub-characterizedinto plastidic and cytosolic subgroups, based on the motif structure, domain characterization andphylogenetic analysis. Protein-ligand interaction studies using molecular docking approach indicatesthat the benzimidazole fungicide (Carbendazim; CID: 25429) interact with G6PDH (PDB Id – 6e07) atvarious positions amino acids thereby suggesting that G6PDH structure get modified by the action ofthe fungicide, thereby affecting the enzyme activity. Chickpea seeds were stressed with differentconc. of fungicides and samples were analysed for total protein content and G6PDH activity byspectrophotometric as well as in-situ enzyme activity. It was observed that the with the increase infungicide stress the total protein content showed a transient behavior and decreased significantly. The activity of G6PDH also get transiently affected under fungicides stress. It was observed thatwith the increase in the conc. of Carbendazim (CARB), the activity of G6PDH enzyme also increased.Two-fold increase in the activity of G6PDH was observed at 0.1% conc. of CARB as compared to controlwhereas higher and lower conc. of fungicide showed a differential behavior. SinceGlucose-6-phosphate dehydrogenase (G6PD) is the key enzyme of the pentose phosphate pathway thatcatalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolactone and is a potentialregulator for various biosynthetic pathways thereby indicating that fungicides interfere the OPPPpathway through differential regulation of G6PDH thereby affecting carbon metabolism in chickpea.

Dr Vikram Jeet SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICAR-Indian

Agricultural Research InstituteDesignation : Research

Fellow

Main impediment of almost of all male sterile lines is panicle enclosure within the sheath whichgreatly reducing seed production of hybrid rice. To resolve this problem, GA3 application has beenroutinely used to improve panicle exsertion, which increases the cost of seed production. Riceinternode is an important trait that affects plant height, lodging resistance and panicle exsertion.The recessive genotype (eui) with the elongated uppermost internode is very useful trait in hybridrice seed production. So far, two eui genes for elongated uppermost internode have been reported.One was identified as a mutant in japonica variety named as eui1 in chromosome 5 through the use ofprimary trisomics. Another gene eui2, was a mutant from indica parents using microsatellite markerslocated on chromosome 10. Therefore, incorporation of these genes into several male sterile linesand restorer lines will help in complete exsertion of the panicle promoting good out crossing thusincreasing yield of hybrid rice. In the present context for genetic analysis and molecular mappingof elongated uppermost internode, we generated mapping population of cross between two contrastingparents with respect to elongated uppermost internode, RTN10B, a maintainer line having shorterupper internode and IRG21 (International Rice Germplasm) line collected form IRRI, Philippines,having average length of uppermost internode of 43.8 cm. Best selected F1 plant was selfed togenerate mapping population consisting of 400 plants. Polymorphism survey between the parents willbe done using SSR markers distributed equally throughout the 12 chromosomes. To understand thegenetics of elongated uppermost internode the individual plants in F2 population will be phenotypedfor elongated uppermost internode and genotying will followed by using putatively linked markersindentified by using Bulked Segregant Analysis (BSA). The identified gene may further beincorporated to male sterile lines to overcome the problem of panicle exsertions.

Mr SWAPNIL PANDEYImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-NBRI


Betula utilis (BU) (family Betulaceae) is an important medicinal plant that grows in high altitudesof the Himalayan region in India. The plant parts are utilized as antibacterial, hepatoprotective,anti-tumor, etc. Here, we demonstrated the lifespan promoting and amyloid-?-induced toxicityattenuating activity of BU in a multicellular model organism, Caenorhabditis elegans. Our resultsshowed that the ethanolic extract of BU (50?g/ml) extended the mean lifespan of Caenorhabditiselegans by 35.99% and increased its survival under both oxidative and thermal stress conditions. TheBU (50?g/ml) also suppressed the levels of intracellular reactive oxygen species significantly by22.47%. The BU treatment significantly improved the survival of CL4176 worms in response toproteotoxic stress-induced by A? protein aggregation. Interestingly, the BU (50 ?g/ml)supplementation was also able to reduce the aggregation of Parkinson’s related protein,?-synuclein in the transgenic strain NL5901 and improved chemotactic behavior in wild-type C.elegans. Moreover, the BU-mediated lifespan extension was found to be dependent on mev-1, daf-16,hsf-1, and skn-1 but not a sir-2.1 gene. Transgenic reporter gene expression assay showed that BU(50?g/ml) treatment enhanced the expression of stress-protective genes such as sod-3 and gst-4.Therefore, the present findings suggested that reactive oxygen species scavenging andinsulin/insulin-like growth factor signaling pathways partly involved in BU-mediated lifespanextension. Thus, BU may target multiple longevity mechanisms to extend lifespan and have a potencyto prevent neuro-related disease progression.

Dr BILQEESA BHATImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : VIGYAN PRASAR, NEW DELHI

Designation : PROJECT SCIENTIST

The current study was carried out to functionally characterize, and explore the hypocholesterolemic potential of probiotic strains isolated from infant feces for management of cardiovascular diseases (CVD). The six probiotic strains showed strong auto-aggregation, hydrophobicity and co-aggregation, activities and all of them fermented vast range of carbohydrates. Furthermore, all probiotic strains exhibited antimicrobial activity against a broad range of bacterial pathogens, and displayed antibiotic susceptibility towards eleven conventional antibiotics. Tested strains produced extracellular proteases, lipases, amylase and bile salt hydrolase (BSH) activity. Both qualitative and quantitative BSH activity of all six probiotic strains was studied in depth. The probiotic strains F9 possessed the highest BSH activity (57.62±0.74nmol/mL per min nmol glycine), while as F3 and F9 displayed strong deconjugation ability by releasing 24.91±0.144 and 22.25±1.86 µmol/mL of cholic acid in the growth medium. Isolate F2 and F5 exhibited highest cholesterol lowering potential of 74.43±0.905%, and 70.63±0.650%, respectively. Strain F5 and F4 showed highest cholesterol coprecipitation as compared to other tested strains. At cell wall concentration corresponding to 1.0 mg/mL, strain F4 showed 27.73±0.362% cholesterol lowering activity. All the six strains showed appreciable cholesterol sequestration activity from mixed micelles. Probiotic strain F4 showed short chain fatty acid (SCFA) producing potential after 12h of incubation. Strains F2, F3 and F9 exhibited remarkable cholesterol lowering potential. The probiotic strain F6 with efficient probiotic characteristics and hypocholesterolemic potential were identified as Enterococcus faecium F6 (MG754450). The probiotic candidates with characteristic probiotic properties and significant cholesterol lowering potential may be used for managing the hypercholesterolemia. Keywords: Probiotics, Enterococcus faecium F6, Hypocholesterolemia, SCFA, BSH, CVD

Dr Mohan TCImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : JSSAHER,

MysoreDesignation : Assitant

Professor

Email: [email protected] Arsenic (As) is a highly toxic metalloid to all living organisms. It has been classified as a class I carcinogen by the International Agency of Research on Cancer (IARC). The natural occurrence of arsenic in groundwater is a worldwide problem. The World Health Organization (WHO) estimates that more than 100 million people worldwide are affected by arsenic poisoning primarily through arsenic-contaminated drinking water. Arsenic enters the food chain because arsenic-contaminated water is used for agriculture. Rice is the major crop grown in arsenic affected regions, rice accumulates more arsenic in the grains compared to other crops. Therefore, people who use rice as their staple food are under the threat of As poisoning. To overcome the detrimental effect of As and to address arsenic contamination in food, our current project seeks to contribute to developing safe crops which can be grown in As contaminated soil but minimize/reduce the uptake and/or translocation of As to edible part. Plants have an inherent capacity to cope arsenic stress by producing cysteine-rich metal-chelating peptides called phytochelatins (PCs). PCs play an important role in arsenic detoxification in plants by sequestering As to the vacuole and reducing the bioavailability of arsenic. Our recent study in transgenic Arabidopsis and Tobacco developed an As tolerant phenotype caused by the reduction of a plant hormone called cytokinin that led to the activation of As tolerance mechanisms and increased accumulation of phytochelatins, which are essential for arsenic detoxification (Mohan et al., 2016). Based on this result, in our current project using genetic engineering tool we are aiming to manipulate endogenous cytokinin hormone to develop arsenic tolerant rice with reduced/no arsenic accumulation rice grains. References: Mohan, T. C., Castrillo, G., Navarro, C., Zarco-Fernández, S., Ramireddy, E., Mateo, C., Leyva, A. (2016). Plant Physiology, 171(2), 1418–1426.

Dr MUKUL JAINImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : JAWAHARLAL

NEHRU UNIVERSITYDesignation : RESEARCH

SCHOLAR

Polyglutamine (polyQ) repeat disorder lead to neurodegenerative diseases that form aggregates in thenucleus and cytoplasm of affected neurons. The autophagy-lysosome pathway maintains cellularhomeostasis and protects against neurodegenerative disorders. Recent findings show that autophagycan be impaired in these diseases and maybe it’s the key factor which aggravated this disorder.Here, we experimented that D. discoideum, which is a simple eukaryotic cellular system to studyabout aggregates and its relation with autophagy. We engineered D. discoideum cells with variedpolyQ repeat lengths (25Q-216Q) and show that a range of mediocre polyQ (43Q-80Q) exhibitedinsoluble protein aggregates consisted of ? sheets, displayed cytoplasmic localization, stuntedgrowth, cytotoxicity and multi-tipped phenotype during development, which was a deleteriousphenotype observed in autophagy mutants. No aggregates was observed in higher polyQ (120Q, 216Q),demonstrated a diffused pattern of fluorescence. Treatment of modulators of autophagy imposesvariation in the number, size and cellular toxicity of protein aggregates, the outcome could bederived from the combination of multiple defective pathways However, we have observed increasedaccumulation of aggregates of 43Q and 71Q in atg1- and atg8- mutant, this increased accumulationcaused cytotoxicity, which was due to impaired autophagic clearance. Finally, we demonstrated thatthe increased accumulation of aggregates under autophagic deficiency dramatically reduced theviability of cells. Therefore, our results suggest that the maintenance of proper levels of cellularautophagy is important to protect cells against the toxicity induced by the accumulation of proteinaggregates These observations established D. discoideum as a new model system for studying CAGrepeat causing neurodegenerative diseases.

Ms HUMIARA RANIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : amity

universityDesignation : RESEARCH

SCHOLAR

Highly stable humidity sensing activities of biosynthesized copper nanoparticles[AIB/RA/2019/236/] Humaira Rani1, Samiksha Sikarwar2, Akhilesh Kumar Singh* Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow-226028, India.1 Department of Applied Physics, School for Physical Sciences, Babasaheb Bhimrao Ambedkar University, Lucknow, U.P., India.2 *Corresponding author e. mail: [email protected] Abstract The present paper reports the biosynthesis of copper nanoparticles by Mangifera indica using copper sulphate pentahydrate (CuSO4.5H2O) as precursor. The copper nanoparticles were investigated using UV–Vis absorption spectrophotometer and Transmission Electron Microscope (TEM). The TEM analysis depicted the minimum grain diameter as 4-7 nm. The energy band-gap of the nanoparticles as estimated from the Tauc plot obtained from UV-Vis spectrum was 2.84 eV. Thin film was then fabricated from the solution of copper nanoparticles using spin coating technique then for the application of impedance based electrical humidity sensor. The average sensitivity was found to 1.92 M?/ % RH for the entire range of % RH with ~97% repeatable results. The response and recovery times of the reported sensor were found as 42.5 and 111 s respectively. Experiments were repeated time to time to check the ageing effect. copper nanoparticles depicted highly stable humidity sensor. References: 1. S. Sikarwar, B. C. Yadav, “Opto-electronic humidity sensor: A review,” Sens. Actuators A: Phys., 2015. vol. 233, pp. 54–70,

Dr Ujjwal DahiyaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-IGIBDesignation : Post Doc

Cell penetrating peptides (CPPs) are a diverse set of small peptides, with distinct set of properties and prospective applications because of their inherent ability to enter insider cell without damaging the membrane. CPPs are widely explored for carrying small molecular drug and other bio therapeutics inside cell in efficient manner because of their higher uptake, biocompatibility and availability of multiple cargo linking strategies. However once inside the cells, retention of these biomolecules or rate of recycling is largely unexplored in the literature. Cellular retention of cargo carrying CPPs can significantly influence availability of biotherapeutic cargo inside the cell and thus its efficacy. In this work, we have studied cellular uptake and retention of multiple CPPs differing in physiological properties, amphipathicity and terminal cysteine modification. For studying retention, cellular fluorescence was tracked after incubating the cells with FITC labelled CPPs using flow cytometry and the corresponding retention profile was obtained by normalizing with initial uptake. We also conjugated selected CPPs with small apoptotic peptide sequences for understating the role of retention in governing the anticancer activity of these conjugated bio-functional peptides. Our study shows prominent role of terminal cysteine modifications of peptides in improving their cellular retention. This works also highlight the importance of intracellular cargo release from the peptide in determining the delivery efficacy of the bio-therapeutic cargo.

Mr Arnab BanerjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Serampore

CollegeDesignation : Research

scholar

Background: In the present era with busy working life and lack of physical work or exercise most ofthe peoples are dependent on fast food yet in addition from nearby cafe or road sides which areexceptionally alluring and extremely fiery too for the younger generation. This type of food isprepared with most widely used food additives monosodium glutamate (MSG) with hydrogenated fats orsaturated fats which is/are inducer of oxidative stress and the ultimate major outcome isnonalcoholic fatty liver disease (NAFLD) worldwide. Problem: Failure of powerful treatmentendeavors are being made to discover reasonable naturally occurring home grown medications. Giventhe unfriendly impacts of medications utilized for nonalcoholic fatty liver disease (NAFLD)treatment, distinguishing novel and successful characteristic compound(s) to avoid NAFLD mediatedsystemic damage is earnestly required. In the present experiment, the impacts of ethanol extract ofCoccinia grandis leaves (EECGL) on NAFLD model were investigated. Methods used: HPTLC and GC/MS foractive components in EECGL. The NAFLD model was constructed with HLD and MSG co administration inrat and a possible protective through EECGL and after the experiment period we have measured somecommon biochemical markers by standard kit using spectrophotometer, inflammatory cytokines bystandard ELISA kit, oxidative stress related parameters by using flowcytometry and biochemically,histopathology, immunohistochemistry for pro-inflammatory factor and apoptosis, some apoptoticmarker proteins by western blot and mRNA expression by RT-PCR, cell cycle analysis and cellularapoptosis via Annexin V/PI. Major results and conclusion: The present examination gives essentialunderstanding into HLD+MSG (HM) interceded consequences for systemic damage and stress. This hastested the metabolic condition prompting an ascent in the inflammatory status, oxidative stress,mitochondrial membrane damage and apoptosis. The discoveries were substantiated with metabolic,clinical and biochemical parameters. This is perhaps the first ever top to bottom report and stays aprecious archive on the deadly impacts of HM with legitimate enhancement. It was seen thatsupplementation essentially improved the HM induced NAFLD mediated oxidative stress and therebyapoptosis. We have found that HM additionally caused loss of mitochondrial membrane potential withexpanded number of necrotic and apoptotic hepatocytes which were blunted by the supplementation withtheir active compound(s). It is perhaps the first comprehensive study with a mechanistic approachthat EECGL can protect HM induced NAFLD mediated systemic damage by scavenging reactive oxygenspecies, inhibiting inflammatory factors, down regulating pro-apoptotic protein and up regulatinganti-apoptotic protein.

Dr SURAIYA SALEEMImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sathyabama

Institute of Science and Technology

Designation : DBT RA

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. It is the most prevalent form of dementia in the world affecting almost 47 million people worldwide (Alzheimer’s Association). The main clinical feature of AD is progressive memory loss, also characterized by the impairment of speech and motor disability, depression, delusions, hallucinations and aggressive behavior [1]. A detailed analysis of the genome of the zebrafish alongwith a comparative study with the humans indicate that the zebrafish possess 70% similarity with the human genome. Zebrafish have been used extensively in developmental biology and molecular genetics. Zebra fish are now being widely used as a predominant model for studying neurodegeneration [2]. In this current study, we have established and validated the amyloid-beta (A?) induced model of AD in Zebrafish. Chitosan nanoparticles loaded with the naturally occurring flavonoid, chrysin, were synthesized. The nanoparticles were validated on the basis of their physical and chemical properties. Namely, SEM, TEM, FTIR, AFM and particle size analysis were performed to validate the nanoparticles thus formed. Amyloid beta was injected intracranially into the zebrafish, which were also given Chrysin orally. It was observed that Chrysin loaded chitosan nanoparticles provided restoration of memory as observed in the behavioural assays. The various assays performed to test memory were spatial memory testing, preference for light and dark environments and their ability to recognize novel objects from the previous objects. Further, it was also observed that the chrysin loaded chitosan nanoparticles led to protection and restoration of synapses of the A? treated zebrafish. Thus, this study provides insight into usage of a naturally occurring flavonoid and polymer for therapeutic purpose in AD. 1. Neugroschl J, Wang S. Mt Sinai J Med. 2011;78, 596–612. 2. Saleem S, Kannan R. Cell death and Discovery. 2018: 4, 45-58.

Dr Shalini AgarwalImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : JNU

Designation : DST Inspire Faculty

Shalini Agarwal1,*, Gaurav Anand2, Shalini Sharma1, Pragyan Parimita Rath1, Samudrala Gourinath1, Alok Bhattacharya1 1 School of Life Sciences, Jawaharlal Nehru University, New Delhi, India 2 International Centre for Genetic Engineering and Biotechnology, New Delhi, India * Corresponding author E-mail: [email protected]

The highly conserved proteins of the 14-3-3 family are universal adapters known to regulate an enormous range of cellular processes in eukaryotes. However, their biological functions remain largely uncharacterized in pathogenic protists comprising of several 14-3-3 protein isoforms. In this study, we report the role of 14-3-3 in coordinating cytoskeletal dynamics during phagocytosis in a professional phagocytic protist Entamoeba histolytica, the etiological agent of human amebiasis. There are three isoforms of 14-3-3 protein in amoeba and we have investigated Eh14-3-3 Protein 3 (EhP3). Live and fixed cell imaging studies revealed the presence of this protein throughout the parasite phagocytosis process, with high rate of accumulation at the phagocytic cups and closed phagosomes. Conditional suppression of EhP3 expression caused significant defects in phagocytosis accompanied by extensive diminution of F-actin at the site of cup formation. Downregulated cells also exhibited defective recruitment of an F-actin stabilizing protein, EhCoactosin at the phagocytic cups. In addition, mass spectrometry based analysis further revealed a large group of EhP3-associated proteins, many of these proteins are known to regulate cytoskeletal architecture in E histolytica. The dynamics of these proteins may also be controlled by EhP3. Taken together, our findings strongly suggest that EhP3 is a novel and a key regulatory element of actin dynamics and phagocytosis in E. histolytica.

Mr niwas kumarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : IITDesignation : SRF

Modified starch based flocculants are highly desirable in the flocculation of green microalgae asthey are cost-effective, biodegradable, and relatively lesser toxic than the other commonly usedinorganic and harmful synthetic flocculants. The present study aimed towards the synthesis ofdifferent grades of cationic starches through the etherification method by incorporation ofquaternary ammonium group from Glycidyltrimethylammonium chloride (GTAC) onto the starch backbone.Various grades of cationic starches with different degree of substitutions (DS) were prepared. Themodified starch pertaining the highest DS was further characterized by scanning electron microscope(SEM), 13 C solid-state nuclear magnetic resonance (NMR), Fourier Transform Infrared(FTIR),Thermogravimetric analysis (TGA), X-ray diffraction (XRD) and Zeta potential measurement.Flocculation behavior of cationic starch was studied towards three indigenous isolated microalgalstrain Chlorella sp. NCQ, Micractinium sp. NCS2 and Scenedesmus sp. CBIIT(ISM) and the optimumdosages obtained for the harvesting of the aforementioned microalgal strains are 65, 61 and 50 mgL-1 respectively.

Dr Suman SahaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Priyamvada Birla Aravind Eye HospitalDesignation : Consultant

Microbiologist

Role of antifungal resistance genes in treatment outcome of fungal keratitis Suman Saha*, Jayangshu Sengupta, Archana Khetan, Debdulal Banerjee *Ocular Microbiology Laboratory, Priyamvada Birla Aravind Eye Hospital, 10 Loudon Street, Kolkata 700017 Cornea and Refractive Surgery Dept., Priyamvada Birla Aravind Eye Hospital Dept. of Botany & Forestry, Vidyasagar University, Midnapore 721102 [email protected]

Background: Resistance to antifungals continues to be a significant problem in the common fungal pathogen. Mechanisms that have been identified include alterations in the gene or overexpression of efflux pump including MDR1, MDR2, and MDR4 and ROD.

Methods:

In the present study, a collection of corneal scraping material and fungal clinical isolates were analyzed for the known molecular mechanisms of resistance by standard methods in a tertiary care eye hospital of eastern India. We have included 25 culture positive fungal ulcer patients for 2017-18. Corneal scraping material was collected for Pan fungal PCR (Polymerase Chain Reaction) and selective genes study. Same procedure was followed for the culture positive cases. Broad spectrum antifungal was given to all and treatment outcome noted.

Results: Among 25 fungal ulcer patients 17 cases were all selective genes positive in both scraping and culture. In 5 cases genes were positive only in culture grown and scraping materials were positive in 2 cases. After having same antifungal therapy the 15 cases where selective genes were actively present in scraping and culture material needed surgical intervention. Medically improvement found in two cases inspite of gene positivity. Among 8 cases of single sample gene positivity 5 cases resolve successfully by medical therapy.

Conclusions: Pan fungal PCR is important for early detection of fungal ulcer which can increases the successful medical treatment in fungal keratitis. Detection of drug resistance genes are playing important role to identify the virulence factor and drug resistant factor of the causative organism.

Mr DEEPAK GUPTAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Institute of Environment & Sustainable

Development, Banaras Hindu University


Appraisal of River Water Quality based on field observations: A case study on Narmada River Deepak Gupta*, Virendra Kumar Mishra Institute of Environment and Sustainable Development, Banaras Hindu University, Varanasi-221005, India

*Corresponding Author Deepak Gupta Research Scholar Lab No-12, Institute of Environment and Sustainable Development, Banaras Hindu University, Varanasi-221005, India [email protected]

Abstract The present research is concerned with the evaluation of the water quality of the Narmada River. Water samples throughout its stretch right from origin point at Amarkantak to Badwani covering 10 sampling stations with 34 sub-sites of Narmada was sampled for water quality. The physicochemical parameters such as pH (8.38±0.4), EC (356±169.8 ?S/cm), TDS (252.8±120.5 mg/L), Alkalinity (157.8±64.7 mg/L as CaCO3), Chloride (58.7±15 mg/L), Total Hardness (161.9±65.8 as CaCO3 mg/L), D.O (4.7±1.6mg/L), B.O.D (2.4±1.6 mg/L for 5 days at 20 ºC), and nitrate (1.8±1.1 mg-NO3/L) was estimated. All parameters were analyzed using APHA, 2012 protocol. Considering these values related to physicochemical parameters of Narmada, comprehensive pollution index (CPI) was implemented to calculate the water pollution level. The results generated through CPI was found 0.05-0.11; indicating that the river is clean. These study may offer useful and relevant findings for river monitoring and its management. Keywords: Narmada, Comprehensive Pollution Index (CPI), Principal Cluster Analysis (PCA), Hierarchical cluster analysis (HCA).

Mr KAPIL DANGIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Department of

ZoologyDesignation : Ph.D Scholar

Microorganisms like bacteria are present all around us and within us, most of them are good for ourhealth and some of them are responsible for a number of diseases for example E.coli( gram –ve) andS.aureus( gram +ve) both are found in intestine of healthy people and animals. However both arealso responsible for causing a number of illnesses from minor pimples to life threatening diseasessuch as pneumonia, meningitis, toxic shock syndrome and sepsis. These can be eliminated by the useof antibiotics but excessive or frequent use of antibiotics leads to antibiotic resistance inbacteria. However other chemical compounds like hydrogen peroxide, ethanol etc can also kill oreliminate bacteria and some other compounds like ascorbic acid and pyridoxine and their synergistic(mixture) can also kill or eliminate bacteria in vitro conditions. Vitamin C, also termed ascorbicacid, is an extensively studied highly potent water-soluble vitamin found throughout the body thatcannot be produced internally in humans. It is a critical mediator of tissue biology, growth,development, and cofactor for several key enzymatic cartilage and bone reactions. Vitamin C alsoexhibits well-established powerful anti-oxidative and anti-inflammatory properties. Vitamin B6,(VB6) pyridoxial hydrochoride functions as a cofactor of many diverse enzymes in amino acidmetabolism. Most unicellular organisms and plants biosynthesize Vitamin B6. However, animals suchas insects and mammals do not possess any of the pathways to biosynthesize Vitamin B6 and, thus,need to intake Vitamin B6 in their diet to survive. Vitamin B6 is not much efficient to kill gramnegative bacteria i.e E.coli but it was noted to kill gram positive bacteria i.e S.aureus.

Dr Showkat Ahmad BhatImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Govt. Medical

College DodaDesignation : Assistant

Professor

Abstract Showkat Ahmad Bhat*, Sabhiya Majid#, Manzoor R Mir~ *Department of Biochemistry, Govt. Medical College Doda, Jammu & Kashmir, India #Department of Biochemistry, Govt. Medical College Srinagar, Jammu & Kashmir, India ~FVSC & AH, SKUAST Kashmir

Background: The post-translational modification of proteins, including glycosylation, is known to differ between normal and tumour cells. In this case control study the genetic polymorphism of five glycosyltranferase genes (ppGalNAc-T6, GlcNAcT-V, ST3Gal I, ST3 Gal IV and ST6GalNAc-I) was assessed in gastric cancer patients and normal controls. Material methods: The study was including 400 individuals among them 200 confirmed GC patients were used as positive controls and 200 normal individuals were used as controls. DNA was extracted from all the blood samples with phenol-chloroform method after isolation qualitative and quantitative analysis of genomic DNA was done by gel electrophoresis and spectroscopy method. The polymorphism was genotyped using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. The gel pictures were analyzed for genotypes for each glycosyltransferace. Results: A significant association was observed between gastric cancer group and control group polymorphism at SetI site of ppGalNAc-T6 gene only. Other three GlcNAcT-V, ST3Gal I and ST6GalNAc-I gene did not revealed any significant association in gastric cancer and control group polymorphism at SetI site. However, SetI enzyme did not digested any amplicons of ST3 Gal IV gene. Conclusion: our results demonstrated that gene polymorphisms of ppGalNAc-T6 gene may act synergistically to increase the risk of gastric cancer. Key words: Gastric cancer, glycosyltransferases, Genotyping, Restriction enzymes

Dr Samita KunduImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Vivekananda

College, ThakurpukurDesignation : Assistant

Professor

The pharmaceutical revolution has ushered in a new era of newer lifesaving drugs to enhance the life span. However, an inevitable consequence of the increased usage has resulted in their higher discharge into the aquatic environment. Pharmaceutical contamination is an emerging kind of aquatic pollution, by which chemicals get into surface and ground waters. These may come from patients, either as the parent compound or metabolites; or through direct release from manufacturing units, hospitals and domestic discharges. Such contamination might have adverse effects on aquatic life. Fish being the major aquatic fauna, are constantly exposed to all sorts of contaminants and hence are used as excellent biological markers for toxicity studies. Harmful effects of antibiotics, steroids, non-steroidal anti-inflammatory drugs have already been documented. But there were no studies on the effects of the analgesic-antipyretic drug, acetaminophen (Paracetamol). Due to less side effects compared to similar other drugs, it is very widely consumed. Consequently, there is more excretion of its metabolite and accumulation in the water bodies. Although potentially less toxic in pharmacologic dose, it is highly toxic to humans in overdose. This happens in the aquatic system when the accumulated concentration becomes toxic to the inhabitants. In a brief study on the effect of acetaminophen of fish, some alarming effects on certain biochemical parameters were observed. There were increased activities of the marker enzymes, alkaline phosphatase and glutamate pyruvate transaminase in liver conforming to hepatocellular damage. Moreover, catalase levels decreased denoting impaired antioxidant defence mechanism. Similar enzyme activities were also observed in brain tissues relating to altered behaviour. Thus, this short term pilot study may be regarded as an emerging indicator of some adverse effects of acetaminophen in fish. This could potentially imply more harmful effects in the future if its consumption and discharge is not regulated.

Ms Raagavi BImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : SSN College

of EngineeringDesignation : M.E - Applied

Electronics

Wireless Underground Sensor Networks (WUSNs) system lays out a suitable technology for transmittingthe agricultural data in the underground (UG) medium for achieving automation. The challenging UGenvironment is no longer air but soil, minerals, sediments and water. The UG applications includeanimal tracking, intruder detection, agriculture soil monitoring, and underground resourcesidentification. The traditional electromagnetic (EM) waves do not work well in this environment dueto high attenuation rate, dynamic channel condition and large antenna size. Unlike EM waves, anemerging technique involving magnetic induction (MI) coils creates constant channel condition andcan accomplish the communication with small size coils. But there exists some challenges in MIcommunication techniques which includes low power reception, limited transmission distance and highpath loss. Therefore ‘Metamaterial enhanced Magnetic Induction’ (M2I) based UG communication isproposed where the metamaterial (MM) will be placed between the transmitter MI coil and receiver MIcoil. MM is an artificially engineered material with unusual EM property like negative index ofrefraction. Due to this property, the MM converges the magnetic field by refracting the signal fromthe transmitter MI coil into the receiver MI coil where the mutual inductance gets increased. Anegative permeability MM (MuMM design has transmission coefficient of -2.95dB, reflection coefficient of -6.44dB, permeabilityof -880.38. Optimization techniques will be performed after which the MM will be fabricated andimplemented along with the MI coil system to enhance the received signal strength. Experimentalanalysis will be carried out at both in-lab test bed (225cm x 30cm x 30cm tank) and outdoor UGfields. This M2I based UG wireless communication system can be used to transmit the sensor data likemoisture, humidity and temperature levels to the farmer’s mobile app using cloud.

Prof MAITRI CHAKRABORTYImage Delegate ID Theme Details


Research


K.S.RANGASAMY COLLEGE OF ARTS AND SCIENCE

(AUTONOMOUS)Designation : ASSISTANT

PROFESSOR

Myocardial infarction (MI) is an acute necrotic disorder of the heart which is by the year of 2020 expected to be the chief reason for mortality worldwide. MI is the necrosis of heart muscle which might occurs because of the imbalance between oxygen supply and myocardial oxygen demand. MI is said to be the principal reason of death for both men and women across the world. MI is characterized by structural and functional modifications in the myocardium resulting in contractile dysfunction, ventricular dilation and subsequent heart failure. Hypercholesterolemia, Hyperlipoproteinemia, larger amounts of LDL cholesterol and lower level of HDL cholesterol are the main hazard factors for MI. Activity of BCA in ISO-induced Myocardial Infarcted Rats was evaluated and the effect of BCA on lipid profiles and cardiac markers in ISO-induced MI in Rats were tested clinically and the result was compared with normal control rats. ISO (isoproterenol), a manufactured ?-adrenoceptor agonist, has been found to initiate MI in rodent because of unsettling influence in physiological harmony between generation of free radicals and antioxidative protection framework. Catecholamine produces free radicals that initiate cardiotoxicity. Biochanin-A (BCA), is a compound found in red clover, cabbage, and alfalfa; shows wide spectrum of pharmacological activities such as antidiabetic, anticancer, antiallergic, anti- inflammatory, Hepatoprotective, Cardioprotective and neuroprotective. In addition, in vitro studies suggest that BCA is a powerful radical scavenger in the presence of transition metal ions . So far, the effects of BCA against metal toxicity in rats have not been investigated. BCA, an isoflavone compound suggested to play a significant role in protecting heart disease. Our finding suggests that pre-treatment of animals with the sample for 28 days significantly protected rats from myocardial damage.Thereby, the present study provided experimental evidence that BCA maintained the antioxidant enzyme levels and improved cardiac performance following high-dose ISO administration.

Dr Parul TripathiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Amity

universityDesignation : research

scholar

Background: There is a very close relation between polymorphism and cancer, from carcinogenesis to tumor-bearing state and from treatment to its prevention. Protein p16, a key regulator in cell cycle, is commonly associated with cancer as a marker for malignant transformation. Single-nucleotide polymorphism (SNP) of p16 exon3 (C540G) has been found to be linked with tumor aggressiveness. Problem: To assess the association of SNP of p16 C540G (rs11515) in oral squamous cell carcinoma (OSCC); patients with oral lesions and healthy individuals. Methods: p16 gene SNP was studied by polymerase chain reaction (PCR) followed by restriction fragment length polymorphism (RFLP) in patients of oral lesions or OSCC and compared with age matched healthy controls. The test group consisted of 226 samples (170 oral lesions – oral sub mucous fibrosis, leukoplakia or erythroplakia, and 56 OSCC); whereas the control group consisted of 103 individuals without a history of oral lesions. Genotype and allele frequencies were analyzed by chi-square test and strength of associations by odds ratio with 95% confidence intervals. Results: The result demonstrates that people having p16C540G carrier genotypes 540 (CG/GG) have protective association for development of leukoplakia (P = 0.004, Conclusions: The results suggest significant association of p16 C540G (rs11515) polymorphism of cell cycle control gene with deceased risk of one of the oral lesions that is leukoplakia. Thus, genetic variants in cell cycle regulatory gene p16 may have potential to emerge as a biomarker for oral leukoplakia. The study may contribute to planning future studies for better understanding of pre-cancerous lesions, their progression, behavior and prognostic markers. Keywords: SNP, leukoplakia, oral squamous cell carcinoma, p16, polymorphism

Dr Shashikant RayImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Mahatma Gandhi Central University

Motihari, BiharDesignation : Assistant

Professor

Shashikant Ray1,2*, Hemendra Pal Singh Dhakad2 and Dulal Panda21Department of Biotechnology,Mahatma Gandhi Central University Motihari, Bihar-8454012 Department of Biosciences andBioengineering, Indian Institute of Technology Bombay,Powai, Mumbai-400076Contact Author’se-mail address: [email protected]: Cathelin related antimicrobial peptide(CRAMP), a 37 amino acid residue cationicpeptide, is thought to regulate innate immunity andprovide host defense mechanism inmammals. CRAMP (16-33) (GEKLKKIGQKIKNFFQKL), a part of the CRAMPpeptide, hasbeen reported to display antimicrobial activity. In this study, we found that CRAMP16-33inhibited the growth of B. subtilis and E. coli cells. CRAMP (16-33) (10 µM)treatmentincreased the length of bacterial cells by 4.7 folds. CRAMP (16-33) treatment perturbedthelocalization of FtsZ-ring at the midcell of bacteria. However, it did not damage themembranestructures of B. subtilis cells. Light scattering and electron microscopic analysis oftheassembly of FtsZ indicated that CRAMP (16-33) inhibited the assembly of purified FtsZ.Invitro, the peptide suppressed the GTPase activity of FtsZ but did not inhibit the bindingofGTP to FtsZ. In vitro, CRAMP (16-33) directly interacted with B. subtilis FtsZ andinducedconformational changes in FtsZ. A computational analysis indicated that CRAMP(16-33)binds in the cavity of T7 loop of FtsZ and both hydrophobic and ionic interactionsareinvolved in the binding of CRAMP (16-33) to FtsZ. Further, salt decreased the polymerizationinhibitory effect of CRAMP (16-33) suggesting that the interaction is mostly ionic in nature. Inaddition, CRAMP (16-33) did not appear to inhibit tubulin polymerization and did not lyze humanRBC. The results together suggested that CRAMP (16-33) inhibitsbacterial proliferation byinhibiting FtsZ assembly and it has potential to act as a novel broadspectrum peptide basedantibacterial agent with high efficacy and new mode of action.

Dr saurabh pandeyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICGEB

Designation : RA

Rice and maize go to family Poaceae contains many crops of agronomic trait and also represent C3 and C4 carbon systems. Analysis of the maize sequence provides new insights into the employment of C3 genes to the C4 mechanism which allowed us to identify more orthologs in other crops such as pennisetum glaucum a C4 crop. This investigation reports comparative account of genome wide in silico identification of C4 pathway related gene namely CA, PEPC, NADP-ME, MDH, PPDK, PEPCK and PPDK gene family of maize and rice. The annotation of gene, signature motif, protein phophorylation, cis-acting elements, phylogenetic tree construction, chromosomal locations, syntenic mapping and microarray expression analysis of C4 pathway related gene family from both the genomes have been attempted. A total of 30 and 37 C4 pathway related genes have been predicted from rice & maize genome respectively. Multiple sequence alignment and signature motif analysis of these proteins of rice and maize revealed high conserveness. Phophorylation analysis revealed that maize have high number than rice. The phylogenetic analysis of C4 related genes across both plant species clearly resulted in four sub-groups in both plants. In Rice, the 30 genes of C4 pathway related genes family are distributed on eleven out of twelve chromosomes, while in maize, they are randomly distributed on all the chromosomes. Most of the genes of Zm’s chromosome 1 show syntenic relationship with chromosome 1. The cis-regulatory-elements of Zm and Os genes suggested its diverse functions associated with plant growth development, stress and hormone responsiveness as well as endosperm and meristem speci?c gene expression. This investigation of Zm and Os can now offer new insights into the role of different C4 pathway related genes and examine the comparative syntenic mapping between model species and allows for the better understanding about how genes evolve within monocots.

Dr WALIZA ANSARImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : behala college


Blood pressure changes in pregnant mothers undergoing spinal anaesthesia at L2-L3 or L3-L4 levels followed by planned Lower Uterine Caesarian Section (LUCS) Sheikh Hasan Habib1, Waliza Ansar2* Julie Bhattacharyya1?, Sourabh Roy3? 1DEMONSTRATOR, PHYSIOLOGY DEPARTMENT , K.P.C. MEDICAL COLLEGE AND HOSPITAL, JADAVPUR, KOLKATA-700032. 2ASSISTANT PROFESSOR, ZOOLOGY DEPARTMENT, BEHALA COLLEGE, PARNASREE, KOLKTA-700060. 3PROFESSOR AND HEAD, ANAESTHESIOLOGY DEPARTMENT , K.P.C. M..C.H ? PROFESSOR, PHYSIOLOGY DEPARTMENT *Corresponding Author

ABSTRACT INTRODUCTION: Spinal Anaesthesia (SA) in Lower Uterine Caesarian Section (LUCS) is a routine surgery . During caesarean section of pregnant women, the utmost responsibility of anaesthesiologist and obstetrician is the safety of both mother and baby. SA may lead to hypotension causing impaired maternal and fetal gas exchange. The number of mothers experiencing hypotension and the number of hypotensive episodes experienced per mother was noted. These values can vary according to level of injection . METHODOLOGY: It is a observational study (N=Number of mother ; N1=30, SA at L2-L3 level; N2=30, SA at L3-L4 level) with full-term pregnant mother (age= 22-30 years) without any systemic illness or without any emergency indication of LUCS were included in this study. All the mothers were infused by 500ml Ringer’s solution before SA. SA was given with Bupivacaine heavy 2.5 ml, but the level of injection was different. During LUCS, blood pressure was measured at 1 min interval till the delivery of baby and at 3 min interval till completion of surgery. Hypotension was managed by intravenous fluid and 3mg Mephentermine . All SpO2 and pulse rate was recorded by Pulse oximeter. All mothers got moist oxygen inhalation at 2L per min during LUCS. RESULTS: N1:19 mothers experienced hypotension. N2: 7 mothers experienced hypotension. Other clinical parameters were also noted during LUCS. CONCLUSION: The number of mothers experiencing hypotension was significantly higher in mothers receiving spinal anaesthesia at L2-L3 level than that of L3-L4 level.

Ms Rashmi BhattacherjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Zoological

Survey of India, KolkataDesignation : CSIR JUNIOR

RESEARCH FELLOW

The blowfly Chrysomya megacephala is a globally distributed saprophagous fly. They are usually first line colonizers of dead and decomposed carcasses. They show utmost importance in estimating post mortem interval and in analyzing toxic chemicals which could have triggered death. Along with forensic entomological studies they also have implications in public health. Remarkably, the larvae can cause accidental myasis and adults are mechanical carrier of a range of pathogenic bacteria (Salmonella typhi), fungi (Aspergillus spp., ), some protozoa and viruses. This work is specifically based on identification of sensilla on the mouth parts of adult Chrysomya megacephala by scanning electron microscopic (SEM) study.All body parts of the selected fly species bears several types of sensilla and covered by microtrichia (except ovipositor) and mechanoreceptors. The sensilla are used for locating oviposition sites, conspecific mates, food and shelter etc. The proboscis is divided into three parts – basally situated rostrum, median haustellum and terminal labellar lobes. Sensilla and mechanoreceptors are distributed in every segment of the mouthparts including labrum, labium, haustellum and maxillary palp. The superficial fine structure analysis revealed two types of sensilla known as basiconic and trichoid sensilla along with mechanoreceptors on these segments of mouthparts. Trichoid sensilla are dispersed all over the haustellum whereas much denser population of basiconic sensilla can be found on the maxillary palp. Microtrichia are distributed all over labium, labrum and maxillary palp but haustellum is completely devoid of microtrichia. These sensilla contains huge number of osmoreceptors which helps to detect ammonia and sulphur-rich volatile chemicals even from considerable distances.

Keywords: Chrysomya megacephala, Forensic fly, SEM, Mouth parts, Sensilla .

Reference: 1) Li S.; Zhang W.;Wang X.; Lei C.; Zhu F.; Am. Entomol. Soc. 2016, 126, 52-63. 2) Sukontason et al.; Micron. 2004 , 35 , 671-679. 3) Sontigun et al.; PARASITE VECTOR. 2018, 11, 415.

Mr Sumit kumar SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-

CENTRAL DRUG RESEARCH INSTITUTE

Designation : SRF

In this era of rapidly advancing science and technology, the role of traditional knowledge regarding medicinal plants which was repeatedly ignored has now become extremely important. According to Pan et al. (2013) the traditional knowledge base boosts the success rate of drug discovery up to 2500 folds. Such a change has happened for several different reasons which includes the availability of in-vitro bioassays and the relative ease of the identification of bioactive compounds. The present study is on Lantana camara L. which is a well-known notorious weed and also a popular ornamental plant. Traditionally it has been in use for the treatment of ulcers, allergies, wounds and some other diseases in many Asian and middle eastern countries (SR King 1999). A variety of pharmacologically active triterpenes and iridoid glycosides have been previously reported from its parts (Ghisalberti 2000). We have investigated the in vitro anti-proliferative activity of Lantana camara leaf ethanolic extract and its fractions and further developed the UPLC-ESI-TQD-MS/MS method for rapid de-replication of the phytoconstituents present in the bioactive fraction. The antiproliferative activity was evaluated against five human cancer cell lines, such as A549 (non-small cell lung cancer cells), C-33A (Cervical squamous cell carcinoma), DU145 (human prostate carcinoma), KB (Human papillomavirus-related endocervical adenocarcinoma) and MCF-7 (human breast adenocarcinoma) using the sulphorhodamine B (SRB)assay. Seven compounds viz. 22?-acetoxylantic acid, lantanolic acid, lantic acid, icterogenin, Camaric acid and 3-Oxo-olean-12-en-28-oic acid in ESI+ and Lantadene D, in ESI- were found to be present in significant amounts in HX fraction. These compounds were identified and characterized using UPLC-ESI-TQD-MS/MS analysis along with UPLC-DAD technique. The present investigation indicated that L. camara leaves possess potent anti-proliferative activity. Further investigations indicated that the three major compounds viz. Lantalonic, Lantic Acid, Icterogenin and their isomers might be responsible for the anti-proliferative activity.

Ms K PavithraImage Delegate ID Theme Details


Research


K.S.Rangasamy College of Arts and Science


Polyherbal Tooth Powder - A Possible remedy for Dental Caries caused by Staphylococcus aureus

Balakrishnan Arumugam*, K.Pavithra and G.Saravanan

Department of Biochemistry, Centre for Biological Sciences, K.S.Ramgasamy College of Arts and Science (Autonomous), Tiruchengode, Namakkal-637215, Tamilnadu, India, E-mail: [email protected]

ABSTRACT : Plants are habitually used in the prevention and treatment of several diseases in most part of the world and it is still widely practiced today. Oral and dental hygiene is the primary and vital component to lead a healthy life. Poor and improper hygienic practices may lead to teeth and gum diseases, dental cavities, and plaque etc., There has been constant effort to focus on interception and correction of disease entity but today our horizon has broadened the approach and goal remains to prevent the disease process rather than to correct it. The objective of the present study was to formulate polyherbal toothpowder using commonly available medicinal plants which includes neem leaves, acacia bark and Kedrostis foetidissima (appakovai) and to evaluate its medicinal properties. Polyherbal toothpowder is subjected to phytochemical analysis and tested for its antimicrobial activity at different concentrations (50 - 500mg/ml) by agar well diffusion method. Polyherbal tooth powder exhibited significant antimicrobial activity against Staphylococcus aureus strains with a maximam zone of inhibition at 500mg/ml concentration which may be due to the presence of different phytoconstituents in polyherbal tooth powder. Totally 11 active phytoconstituents have been identified in methanolic extract of polyherbal tooth powder by GCMS analysis. Physiochemical properties evaluated using standard parameters ensured the quality of the formulated polyherbal tooth powder. The results of the study demonstrated that the formulated polyherbal tooth powder have promising antimicrobial activity that supports the traditional usage of plants as therapeutics and may be safer and effective approach towards preventive oral care.

Keywords: Oral and Dental Diseases, Staphylococcus aureus, Polyherbal Tooth Powder, Oral Hygiene

Ms ANUBHUTI SINGHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Institute of

Environment and Sustainable Development, BHU,VaranasiDesignation : RESEARCH

SCHOLAR

Characterization of Bioactive compounds isolated from endophytes of Withania somnifera and their antagonism against fungal pathogens 1Anubhuti Singh*, 2Rachna Singh, 2Naveen Kumar Arora, 1V.K Mishra 1Institute of environment and sustainable development, Banaras Hindu University, Varanasi-220015 2Babasaheb Bhimrao Ambedkar University, Lucknow-226025 [email protected] Agriculture in tropical and subtropical countries suffers severe losses due to pests and phytopathogens. To protect their crops, farmers apply an excessive number of synthetic agrochemicals and pesticides. Currently, plant endophytes are viewed as an outstanding source of bioactive compounds that can be used as biopesticides against many phytopathogens. Endophytes exhibit complex interactions with their hosts which involves mutualism and antagonism. Plants limit the growth of endophytes and these endophytes use many mechanisms to gradually adapt to their living environment. In order to maintain stable symbiosis, endophytes produce many compounds that promote the growth of plants and help them to adapt to harsh environmental conditions. Due to the above mentioned metabolic and physiological properties of endophytes which affect greatly the growth and fitness of their hosts, these organisms are viewed as a valuable tool for sustainable agricultural practices. IR spectrum was used to recognize the functional groups of active compounds based on the peak value of the Infrared region. Based on the activity of the compounds these endophytes can be selected as a novel source of antipathogens and hence boost up agricultural needs. On one hand, where most of the biocontrol agents have not fulfilled their initial promise; their failure usually being attributed to poor rhizosphere competence and the difficulties associated with the instability of biocontrol agents in long-term culture the intimate relationship between endophytes and their hosts make them natural candidates for selection as biocontrol agents and would obviate it for rhizospheric competence. Key Words: Agriculture, Phytopathogens, Endophytes, Bioactive compounds

Dr Hans Raj BhatImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dibrugarh

University, Dibrugarh AssamDesignation : Assistant

Professor

Design, Synthesis and In-Vitro Antimalarial Evaluation of 1,3,5-triazine derivatives

Hans Raj Bhat*1, Anshul Shakya1, Surajit Kumar Ghosh1,Udaya Pratap Singh2, and Dibya Ranjan Bhattacharya3

1Department of Pharmaceutical Sciences, Dibrugarh University,Dibrugarh, Assam-786004

2Drug Design & Discovery Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture Technology & Sciences, Allahabad-211007

3Regional Medical Research Center, ICMR, Dibrugarh, Assam.

Email: [email protected]

Abstract Purpose: The emergence of drug-resistant strains of Plasmodium falciparum to the artemisinin-based combination therapy (ACT)1, has dramatically reduced the chemotherapeutic options. The present study deals with the synthesis of novel 1,3,5-triazine derivatives as antimalarial agents. Methods: The designed compounds were synthesized via sequential nucleophilic substitution reaction to afford title compounds and in-vitro antimalarial evaluation against chloroquine-sensitive (3D-7) strains of P. falciparum by Giemsa stain method. Results: The synthesized compounds were characterized by different spectroscopic methods such as FT-IR, 13C-NMR, 1H-NMR, Mass and elemental analysis. Among the synthesized compounds only disubstituted para chloroaniline 1,3,5-triazine derivative showed better antimalarial activity (% dead rings + schizonts) using chloroquine as reference drug. Conclusion: Novel 1,3,5-triazine derivatives can be used as prototype for development of new antimalarial agents. References: 1. World Malaria Report, WHO, Geneva, Switzerland, 2018.

Mr ANISH KUMAR TIWARIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : UNIVERSITY


SCHOLAR

Ion beam induced RNA sequence (mi RNA) revealed the promoted expression of functional protein in Rice plant

Anish Kumar Tiwari1*, Vikas Baranwal2 , Avinash C. Pandey1 1*,2 Nanotechnology Application Centre, University of Allahabad, Prayagraj-211002, India, 1Inter University Accelerator Centre, New Delhi-110067, India

Abstract In nature genetic modification mainly occurs due to mutation. Without mutation, the breeding programme of plants is not possible. There is a number of chemical, biological, physical processes are available to induce mutation but recently ion beam technology emerged as a new form of physical mutagen for the induction of mutation in plants, to produce new verities of various plants, in place of X-rays, Y-rays, and neutrons. Micro RNA are the family of small non coding which play significant role in regulating development and stress responses in plant. To identify the specific miRNA that underlie biological effect of ion beam radiation. The main aim of ion beam induced mutation in plant breeding is to modify and develop Novel mutants (such as drought resistance, high productivity, high nutrient use efficiency etc.) and their related genes. This process is made possible due to high RBE (Relative Biological Effectiveness) of ion beams of growth inhibition, fatality etc. Most effective LET value for inducing mutant sectors without causing severe damage of genetic material is lies between (30-110 KeV/µm). Results awaited but previous studies suggested that ion beam generate high mutation frequency (mutation causes deletion of several base pair long genetic material which results in irreparable DNA damage) as well as wide mutation spectrum. Key words : ion beam , mutation , RBE, LET, mi RNA.

Mr Mark CharlesImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Eras Lucknow

Medical College & HospitalDesignation : PhD Scholar

Background Cervical cancer is one of the most frequent cancers among women in developing countries. According to statistics globally number of new cases of cervical cancer stand out to be 7.4 per 100,000 annually. In India, 122,844 women are diagnosed with cervical cancer and 67,477 die from the disease [1]. The human X-ray repair cross-complementing protein 1 (XRCC1) gene is responsible for DNA repair and may be related to the risk of cancer. We studied the association of Single Nucleotide polymorphisms (SNP) in the DNA repair of XRCC1& XRCC3 genes [2] Problem: Cervical Cancer Methods: All blood samples were collected from histopathological confirmed cases (n=69) and controls of similar ethnicity (n=71) and evaluated for single nucleotide polymorphism analysis of XRCC3 by polymerase chain reaction with confronting two-pair primers (PCR-CTPP). Result: There were no significant difference in age between the case and control XRCC3 genotypes were not associated with an increased risk of cervical cancer (adjusted odds ratio=0.85; 95% confidence interval=0.45-1.6)p value of 0.62. A positive association was observed between the polymorphisms of XRCC1 genes, that is, in codons 194 [P=0.03, odds ratio (OR) =2.39, 95% confidence interval (CI)=5.2–1.1], These findings suggest that polymorphisms of XRCC 1 play a role in the etiology of cervical cancer Conclusion: The present study suggested that polymorphisms of XRCC 1 -194 could offer evidence of the association between polymorphism in XRCC1gene and increases risk for cervical cancer. Further studies with a larger number of participants and simultaneous measurement of different polymorphisms in DNA repair genes in the same pathway are needed

References: 1. Lindsey A. Torre, Farhad Islami, Rebecca L, et al, Cancer Epidemiol Biomarkers Prev.2017, 26(4), 444–57 2. Norppa H. Cytogenetic biomarkers, IARC Sci Publ. 2004, 157,179-205

Dr SEEMA SINGHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : KING GEORGES MEDICAL

UNIVERSITYDesignation : RESEARCH

ASSOCIATE

Background: Chronic obstructive pulmonary disease (COPD) is a non-specific inflammation, which involves the airways, lung parenchyma and pulmonary vessels. The inflammation causes the activation of inflammatory cells and the release of various inflammatory mediators such as interleukin-1 beta, interleukin-4 and tumour necrosis factor alpha (TNF-a).1 The present study was designed to assess the serum cytokines [Interleukin-1? (IL-1?), Interleukin-4 (IL-4), Tumor necrosis factor-? (TNF-?)] levels in chronic obstructive pulmonary disease (COPD) patients and they were correlated with severity of disease by spirometric measurements. Materials and methods: A total of 384 COPD patients and 50 healthy controls were enrolled in this study. 5?ml of venous blood samples were taken from all participants and it was collected in a test tube containing anticoagulant and then centrifuged at 3000?rpm for 10?min. Serum was separated and used to measure the amount of TNF-alpha, IL-1beta, and IL-4. Results: Tnf-? (pg/ml), IL-4 (pg/ml), IL-1? (pg/ml) serum levels in COPD patients and healthy controls subjects were measured. Tnf-? and IL-4 serum levels were significantly ( Conclusion: The present study signifies that the levels of TNF-?, IL-1?, and IL-4 are directly proportional to the post-bronchodilator FEV1 percentage. Overall, these results identify a novel systemic inflammatory COPD phenotype that may be the target of specific research and treatment.

1. Bibliography: Malerba M, Montuschi P. Non-Invasive Biomarkers of Lung Inflammation in Smoking Subjects Current Medicinal Chemistry. Curr Med Chem 2012; 19: 187-196.

Dr Prashant SinghImage Delegate ID Theme Details


Research


Botany, University of Rajasthan

Designation : UGC-Assistant Professor

Title: Green Vaccination: Smart Plant Health Care for Human Welfare

Prashant Singh* *Department of Botany, University of Rajasthan, Jaipur, 302004, Rajasthan, India. [email protected]

One of the biggest challenges for food security in the 21st century is to improve crop yield stability through the development of disease-resistant crops. Plants are constantly exposed to potentially pathogenic microbes present in their surrounding environment.

Despite their effectiveness, chemicals-based plant defense has detrimental environmental consequences and creating risks to the wider environment. Modern synthetic chemicals usually have reduced environmental toxicity; however, they are expensive and only available to advanced agricultural production systems. Moreover, as with antibiotics, discovery of new chemical to control plant disease is difficult and extensive use of current agents may result in selection of pathogen strains tolerant to pesticides. Plants have evolved a sophisticated immune system to resist pests and diseases. Apart from their innate immune system controlling pre programmed defence reactions, plants can also increase the responsiveness of their immune system in response to selected environmental signals. This phenomenon is known as “defense priming”. Although defense priming rarely provides full protection, its broad spectrum effectiveness, long?lasting durability and inherited to future generations make it attractive for integrated disease management. I will discuss the role of plant natural defense and priming in crop improvement and sustainability.

References:

1. Srivastava, Anjil.; Orosa, Beatriz.; Singh, Prashant.; Walsh, Charlotte.; Zhang, Cunjin.; Grant Murray, Grant.; Roberts, Michael.; Srinivasan, Ganesh.; Sadanandom Ari. Plant Cell, 2018, 30, 2099-2115. This is listed in top five paper by The Plant Cell and also included in Nature Index. 2. Singh. P.; Dave, A.; Vaistij, F.; Worrall, D.; Holroyd, G.; Wells, J.; Graham, IA.; Roberts, MR (2017). New Phytologist. 2017, 214, 1702-1711.

Mr ANSHUL SHAKYAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dibrugarh


Professor

Background: Benincasa hispida (Thunb.) Cogn., a member of ‘Cucurbitaceae’ family, is an Ayurvedic ‘Rasayana’, generally known as ‘Kushmanda’. It has been documented for tonic, restorative, rejuvenator and vitalizer properties in Ayurveda. Hence, the current study was designed to elucidate the adaptogenic potential of characterized extract of Benincasa hispida (Thunb.) Cogn. fruit pulp in validated rodent models. Materials and Methods: Chemically characterized the hydroalcoholic extract of Benincasa hispida (Thunb.) Cogn. fruit pulp (HABH) for rutin and quercetin content (i.e. 1.78% and 1.94% w/w, respectively) was used for the study. Effects of repeated daily for 21 days treatment of three different dose levels of the HABH (i.e. 30, 100 and 300 mg/kg/p.o.) as suspension (0.3% carboxymethylcellulose) were evaluated for sensory, motor and behavioural function(s) in chronic unpredictable foot shock (CUF) induced stressed rats using array of validated paradigm viz. response time on hot plate (sensory), muscles co-ordination on rotarod apparatus (motor), forced swim test (depression), light and dark box test (anxiety) and modified elevated plus-maze test (learning and memory). Results: Statistically analyzed data showed that HABH was found significant (p Conclusion: Overall, we conclude that the HABH exhibited adaptogenic potential by preventing the chronic stress-induced disruption in the homeostasis of biochemical markers, sensory, motor and behavioural functions in preclinical setup.

Ms Priyanka RoyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NIFTEM


Food industrial waste valorisation is an innovative idea for production of high value product form low-cost raw material. Juice industry in India produces tones of waste as by-product, that contains high nutrients for microbial growth. But does not have any potential use. That can be used by fermentation industry of production of bioflavour and bioaroma compounds. Bioproduction of aroma and flavour compounds by fermentation is generally regarded as safe for human consumption. Pomegranate peel is one of the waste product of fruit juice industry, that can be used as substrate of solid state fermentation as it's support the growth of many microorganism specially fungi. Ceratocystis fimbriata is one of the studied fungi that produces fruity aroma in different substrate after solid state fermentation. Most of the volatile compounds present in pomegranate peel are Terpenes but after fermentation with C. fimbriata the flavour profile changes. It was observed that some new aromatic compounds such as 1-Dodecanol and furfural produces, that having similarity with apple and pear aroma . Ethyl ester and octadecnoic acid present in 21.30% before fermentation that bit reduces to 20.57%. D-Limoene was present in raw peel in 0.54%, but it was absent after fermentation. Compounds like 1-Tridecene that initially present in peel give some what mild coconut to buttery aroma, does remains after fermentation. After fermentation some fruity aroma was generated.

Dr Sanhita MaityImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : University of

Arkansas, USADesignation : Reserach

associate

Protein aggregation can be merely a troubling factor in many in vivo and in vitro studies of proteins or it can cause major economic and technical problems in the biotechnology and pharmaceutical industries. Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and Prion diseases have common molecular and cellular mechanisms including protein aggregation and inclusion body formation [1,2]. It has been reported from ‘Alzheimer’s Association’ and Dementia statistics that ‘there were an estimated 50 million people worldwide living with dementia in 2017 and this number will almost double every 20 years, reaching 75 million in 2030 and 131.5 million in 2050. Fibroblast growth factors (FGFs) , a superfamily of cell signalling polypeptides, are associated in regulation of wide array of biological processes such as endothelial cell proliferation, cell differentiation, angiogenesis and tissue homeostasis and to name a few. Interestingly, FGFs play a key role in neuroprotection against neurotoxicity in AD[3]. Although the proper mechanism of neuroprotective effect of FGFs are still precisely understood. This work elucidate the understanding of lipid-mediated interaction of FGFs which may constitute a new route to pave the way for modulatory role of FGFs in neurodegenerative diseases. References: [1] Gonzalez,I. M. and Soto, C., (2011), Misfolded protein aggregates: mechanisms, structures and potential for disease transmission, Semin Cell Dev Biol., 22, 482-487. [2] Chiti, F. and Dobson, C. M., (2017), Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade, Annu Rev Biochem., 86, 27-68. [3] Davis, J. E., Gundampati, R. K., Jayanthi, S., Anderson, J., Pickhardt, A., Koppolu, B. Zaharoff, D. A . and Kumar, T. K. S., (2018), Effect of extension of the heparin binding pocket on the structure, stability, and cell proliferation activity of the human acidic fibroblast growth factor, Biochem Biophys Reports., 13, 45-57.

Ms PALAK BAKSHIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Guru Nanak

Dev University AmritsarDesignation : Research

Scholar

Palak Bakshi*, Pooja Sharma**, Mohmad Ibrahim*, Bilal Ahmad Mir***, Renu Bhardwaj* *Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar-143005 **Department of Microbiology, DAV University, Jalandhar. ***Department of Botany, School of Life Sciences, Satellite campus Kargil, University of Kashmir, J&K. [email protected], [email protected]

Extensive pesticides application has become an inevitable part of our environment. It has been estimated that more than 500 formulations are available in the world’s market and worldwide consumption of pesticides reached around 2.6 to 4.6 Tg per year (Alberto et al., 2016). Nowadays, organophosphate pesticides are the commercially favored type of pesticides and extensively used worldwide. The impact of mishandling and extensive application of these pesticides raise the question on environmental quality, ecosystem functioning and sustainability, wellbeing of human as well as other organisms. Their application causes plant growth inhibition, altered chloroplast ultrastructure, photosynthetic rate, and antioxidative defense system thereby generating oxidative stress in plants leading to a decrease in quality and yield of plants. Hyperaccumulators like Brassica juncea removes chlorpyrifos (CP) an organophosphorus pesticide from contaminated soils and break it into non-toxic metabolites under a process named phytoremediation which is assisted with several factors. Microorganisms are an important and essential factor in plant growth and development. Microbial degradation (Burkholderia gladioli and Pseudomonas aeruginosa) is considered as one of the effective options for the removal of these pesticides from the environment. Various biochemical traits studied in the present work included growth, photosynthetic attributes, antioxidative levels, the content of osmoprotectants, organic acids and phenolic compounds in 10 days old seedlings. The observations signify that PGPRs have the potential to confer tolerance against the toxic level of CP by improving growth, photosynthetic activity and altering the activities of different antioxidants and various metabolites by simultaneously improving phytoremediation efficiency. Alberto, D.; Sci. Total Environ. 2016, 569–570, 1618–1628.

Dr Shubhita MathurImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jaipur

National UniversityDesignation : Assistant

Professor

INTRODUCTION: Mycobacterium tuberculosis, the causative agent of human tuberculosis, is a major cause of mortality. BCG, the only licensed vaccine available for protection against tuberculosis confers highly variable protection ranging from 0%-80%. Thus, novel vaccine strains need to be evaluated for their potential as vaccine against tuberculosis. We had previously constructed a triple gene mutant of M. tuberculosis (Mtb?mms), having deletions in genes encoding for phosphatases mptpA, mptpB and sapM that are involved in host-pathogen interaction. Though vaccination with Mtb?mms strain induced protection in the lungs of guinea pigs, the mutant strain was not able to control the hematogenous spread of the challenge strain to the spleens. Additionally, inoculation with Mtb?mms resulted in some pathological damage to the spleens in the early phase of infection. METHOD: To overcome the pathology caused by Mtb?mms in the spleens of guinea pigs and also to control the dissemination of the challenge strain, Mtb?mms was genetically modified by disrupting bioA gene to generate Mtb?mmsb strain. Further, in vivo attenuation of Mtb?mmsb was evaluated and its protective efficacy was assessed against virulent M. tuberculosis challenge in guinea pigs. RESULTS: Our study demonstrates that Mtb?mmsb mutant was highly attenuated for growth and virulence in guinea pigs. Vaccination with Mtb?mmsb mutant generated significant protection in comparison to sham-immunized animals at 4 and 12 weeks post-infection in lungs and spleens of the infected animals. CONCLUSION: Our findings provide evidence that deletion of genes involved in signal transduction and biotin biosynthesis severely attenuates the pathogen and the single immunization with the auxotroph was able to provide significant protection as compared to sham-immunized animals. The protection imparted by Mtb?mmsb fell short in comparison to the protection observed in BCG-immunized animals. This study nevertheless indicates the importance of attenuated multiple gene deletion mutants of M. tuberculosis in generating protection against tuberculosis.

Dr shikha JoonImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : SGRH

Designation : postdoctoral fellow

Introduction & Objectives: Bacillus anthracis, a prioritized bioterrorism bacterium causes the fatal zoonotic disease, anthrax, with humans as contingent victims. It harbors a global transcriptional regulator, CodY which controls diverse cellular activities such as metabolism, sporulation, pellicle, and biofilm formation, and most importantly virulence. GTP and Branched Chain Amino Acids are the metabolic effectors of CodY, which affects its DNA-binding ability. To gain an insight into the interaction mechanism of CodY and GTP and the biochemical reactions that ensue, of which scarce is known presently, we carried out GTP interaction assays in vitro. Methods: We assessed the interaction mechanism of GTP and CodY protein in vitro. In this direction, the cody gene was over-expressed in E. coli expression system and the purified recombinant His6-CodY protein was subjected to GTP interaction assays. Consequently, His6-CodY protein could be crosslinked to the radiolabeled GTP in a UV-crosslinking assay with competitive inhibition by the non-radiolabeled pyrimidine nucleotides. The observed autophosphorylation activity of the recombinant protein was based labile and acid-stable owing to the presence of the conserved serine residue (S215) critical for the activity as the mutant version of the protein (His6-CodYS215A) failed to autophosphorylate under similar assay conditions. An absence of any secondary structural changes in His6-CodYS215A protein was confirmed by CD spectroscopy. A weak GTP hydrolyzing activity was observed in the Thin-layer chromatography assay with the Km and the Vmax of the reaction measured as 0.16 mM and 0.0154 mM min-1 respectively in the coupled enzyme assay.

Dr VIJI VIJAYANImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : National Institute of ImmunologyDesignation : Scientist

WOSA DST

Role of Bone Derived Protein in Preventing Alzheimer Disease Viji Vijayan* and Sarika Gupta Molecular Science Lab, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067 [email protected] Alzheimer's disease (AD), a progressive neurodegenerative disorder is at an alarming rise in India. This disease is typically characterised by amyloid plaque deposition in brain, gradual memory loss and difficulty with language and emotions. As of now there is no cure for AD. We identified that transgenic mice that suffered from excessive amyloid deposits show downregulation in expression of certain genes involved in bone metabolism importantly osteocalcin, an osteoblast specific protein with role in bone mineralization. Here in this study carboxylated form osteocalcin (Gla-OC) was administered to 5xFAD transgenic mice and its therapeutic effect if any was assessed. When Gla-OC was subcutaneously administered to 5xFAD transgenic mice for 2 months after the onset of amyloid deposition, there was improvement in behavioural deficits, substantial reduction in amyloid deposition in cerebral cortex and decrease in oxidative stress and inflammation in brain. Importantly, the population of astrocytes, an important set of immune-competent cells of brain was increased in cerebral cortex of transgenic mice with treatment. To determine the role of Gla-OC in amyloid clearance, astrocytes (EAAT+CD11b-) from transgenic mice were isolated and exposed to Gla-OC and Abeta42. We noted that Gla-OC stimulation led to extracellular uptake of amyloid beta42 and lysosomal activation evidenced by nuclear translocation of transcription factor EB, cathepsin D cleavage and activity and reduction in intracellular level of amyloid beta42. These findings demonstrate novel immunomodulatory role of bone protein and the importance of healthy bone for preventing neurodegenerative disorders. Osteocalcin therefore holds promise as a therapeutic agent for AD. Reference: Braak H et al. Evolution of Alzheimer’s disease and related cortical lesions. J Neural Transm Suppl, 1998, 54: 97.

Mr Shivmurat YadavImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sanjay Gandhi Post Graduate

Institute of Medical SciencesDesignation : Ph.D.

Calcium is one of the important factors determining the bone mineral density (BMD) and hence low calcium intake deteriorates bone micro-architecture and decreases the bone mass and longitudinal growth of the individual. While the other hand high calcium intake increases the BMD in growing children. Bone modeling is an important period of bone growth in growing animal and dietary calcium inadequacy in this period may lead to severe bone damage. Reversibility associated with bone micro-architecture damage due to calcium deficiency in the modeling period is still not clear. In this study, we induced dietary calcium deficiency in growing female Sprague-Dawley rats and checked its reversibility after high calcium replenishment employing the techniques- micro-computed tomography (micro-CT) and dynamic histomorphometry. Our result showed that calcium deficiency in growing animals significantly decreases the trabecular and cortical bone micro-architecture and BMD due to secondary hyperparathyroidism. Reversibility by feeding calcium replenishment diet to calcium-deficient rats revealed that there was an improvement in bone micro-architecture and BMD. However, improvement in trabecular bone was partial while the improvement in cortical bone was complete. Dynamic histomorphometric analysis showed that partial recovery in the trabecular region of bone was due to lower the rate of bone formation (BFR) and bone mineralization (BMR). Recovery result showed that despite the recovery in biochemical markers associated with the calcium homeostasis, cortical micro-architecture and bone BMD, the trabecular bone micro-architecture was still compromised due to under mineralization of bone. Our result clearly demonstrated that dietary calcium sufficiency is crucial for proper bone mineralization, modeling, healthy bone micro-architecture and optimum bone growth in the growing animals. Keywords: Calcium deficiency, BMD, bone micro-architecture, dynamic histomorphometry

Ms Debanjana ChakravartyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : INDIAN

INSTITUTE OF SCIENCE EDUCATION AND

REASEARCHDesignation : Senior

Research Fellow

Neurotropic Mouse hepatitis virus (MHV-A59) induced demyelination serves as a model to understandthe mechanisms of demyelination and concomitant axonal loss in human neurological disease MultipleSclerosis (MS). The acute phase of MHV inflammation is controlled by recruitment ofmicroglia/macrophage to the site of infection, however, the role of T and B cells in viral-inducedaxonal degeneration and demyelination is somewhat controversial. Our current in vivo study showedvery little involvement of CD4+ T cells from day 0-5 post-infection, however, there is significantinfiltration during day 7-10 p.i. There is a gradual increase in its mRNA expression from day 10-15p.i. In order to explore the role of CD4+ T cells during transition from an early protective innateresponse to a highly regulated adaptive response, MHV-infected CD4-/- mice were compared withMHV-infected CD4+/+ mice at days 5/6, 10, 15 and 30 p.i. Viral titer estimation and nucleocapsidgene amplification confirm enhanced replication of the virions in the absence of functional CD4 + Tcells in brain tissue. Viral anti-nucleocapsid antigen staining further shows the persistence ofvirus at day 30 p.i. in CD4-/- mice, unlike CD4+/+ mice. Histopathological analysis of liver, brain,and spinal cord showed an elevated susceptibility of CD4-/- mice to encephalitis and axonaldegeneration with the augmented progression of acute poliomyelitis, bulbar vacuolation, and dorsalroot ganglionic inflammation rarely observed in CD4+/+ infected mice. In summary, the current studysuggests that CD4 T cell is critical for viral clearance, host immune responses and controllingchronic progressive axonal degeneration.

Ms Fareeha SaadiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Indian

Institute of Science Education and Research Kolkata

Designation : SRF

Chronic progressive multiple sclerosis (MS) is characterised by loss of neuronal functions resultingfrom axonal degeneration and demyelination. Infiltration of T lymphocytes and activation ofmicroglia are and their interplay considered to be the major pathophysiological events leading toneurodegeneration in MS. However, the interaction between the two cell types is poorly understood.One of our studies in Mouse Hepatitis Virus (MHV) induced neuroinflammatory model demonstrated thatthe absence of CD4+ T cells makes the mice more susceptible to acute encephalitis and chronicdemyelination with bulbar vacuolization in the axon. In order to understand the impact of CD4+ Tcells on microglial activation, we have investigated the role of microglia in neuroinflammation uponCD4 depletion. Results from our studies showed that a higher number of Iba1+ microglia/macrophagesand viral antigen+ cells persist in the brain parenchyma of CD4-/- mice at the chronic infectionstage in comparison to the WT mice. Also, real-time qPCR screening of inflammatory markers presenteda consistent and unregulated proinflammatory microenvironment in the CNS and comparative higherexpression of antiviral effectors in the brains of CD4-/-. We have also found that the expression ofCD40 receptor (expressed on the microglia/macrophage) and its cognate ligand CD40L (expressedmajorly on CD4+ T cells) increase upon MHV infection and the CD4-/- mice brains show no expressionof CD40L but an increasing expression of CD40. Our findings therefore propose that microglia and Tcell interaction via CD40-CD40L ensures a protective immune response in order to maintain neuralhomeostasis in the Central Nervous System (CNS).

Mr DIPAYAN DASImage Delegate ID Theme Details


Research


OF NORTH BENGALDesignation : RESEARCH

SCHOLAR

The principal and sole food for silkworm larvae is Morus alba. The protein content of mulberry leaves is of key importance as it helps in the development of silk gland, which ultimately leads to the development of high quality silk. The agro based silk industry faces one major problem during rainy season with larval feeding because feeding wet mulberry leaves leads to the development of larval disease, increasing their mortality rate. Leaf preservation by retaining leaf quality may serve as a vital tool for overcoming the above problems. Current study deals with application of phytosynthesized silver nanoparticles for extending shelf life of mulberry leaves at post harvest stage of preservation. Our result indicated significant decrease in chlorophyll content in control set with increase in days of preservation. We observed significant negative correlation (p?0.01) between chlorophyll degradation and generation of ROS. With increase in days of preservation, excessive accumulation of O2•- and H2O2 leads to the generation of oxidative stress. Leaves preserved in nanosilver displays suitable stress tolerance strategy by enhancing antioxidant enzymological activity. SOD converts O2•- into H2O2, present study demonstrated gradual increase in SOD in nanosilver treated leaves, while reversed trend was observed in control set. An increasing trend of CAT, APX and GPOX activity was noted indicating there potential role in scavenging excess H2O2 produced during stress by the activity of SOD. On the contrary GSR is a flavo-protein oxidoreductase which plays crucial role in reducing biotic stress by maintaining ascorbate and glutathione pool in reduced state inside the chloroplast. SDS banding pattern of preserved leaves in nano silver solution appears almost similar to that of fresh leaves, indicating preservative potential of nano silver solution. Upregulation of isozyme activity was observed in nano silver treated set indicating enhancement of antioxidant defensive activity helping in extending postharvest shelf life.

Ms Mithila KambleImage Delegate ID Theme Details


Research


Institute of Science Research and Education Kolkata

Designation : PhD Candidate (UGC JRF)

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disorder driven by humoraland cell mediated responses against self-antigens. It may affect one or more organs and organsystems including the central and peripheral nervous system. Various reports in SLE suggest thatabnormal production of cytokines, complements and autoantibodies, improper clearance of the immunecomplexes and the disruption of the blood brain barrier lead to either direct or indirect neuronaldysfunction. However, studies elucidating the physiological changes in the neuronal cells during thedisease progression are lacking. To decipher the underlying mechanisms of neuronal dysfunction inNPLSE in vitro, we employed the human neuroblastoma cell line SHSY5Y. Human sera were procured fromthree different patient groups; healthy, SLE and NPSLE. SHSY5Y cells were treated with varyingdilutions of sera at increasing time points. Significant reduction in cell viability as analyzed byMTT assay was observed in cells treated with SLE and NPSLE sera. IC50 value was not obtained in anyof these experiments, showing that the sera are not lethal for the cells. Further, assessment ofmorphological changes on serum treatment was performed using immunofluorescence assay and RT-qPCR ofcytoskeletal markers. Morphometric analysis of the cell images showed no significant change in thestructural integrity of the cytoskeletal protein, F-actin. However, it was interesting to note that?-actin and ?III-tubulin showed reduced mRNA expression in SLE as compared to the control group.?-actin being a housekeeping gene and ?III-tubulin found almost exclusively in the neuronalcytoskeleton, are fundamental to normal neuronal function and crucial for axonal growth, guidanceand maintenance. Reduction in expression of these may lead to severe ramifications. This is a newfinding and could be explored as a plausible mechanism for neuronal dysfunction in NPSLE.

Ms Nishi MishraImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : college of agriculture Gwalior IndiaDesignation : Master

Research Scholar

Nishi Mishra*,Vinod K. Sahu, Punamchand Bhawar Department of Plant Molecular Biology and Biotechnology, College of Agriculture, RVSKVV, Gwalior (M.P.) *Corresponding authors mail ID: [email protected] A modern technology is necessary to enhance agricultural production as well as increase nutritious foods in worldwide. In recent years, developed a new genome editing tools CRISPR/Cas for improving traits by efficient targeted modification in crops, thus promising to accelerate crop improvement. CRISPR-Cas-mediated genome editing technologies break the major barrier, providing a tool to induce genetic variation through genomic double-stranded breaks (DSBs) at a desired genomic location, paving the way for trait improvement such as biotic and abiotic stress resistant crop via precise genomic modifications, CRISPR-Cas allows for transcriptional regulation and epigenetic editing with high efficiency and precision. CRISPR-Cas application in plant genome editing is poised to harness the progress made in the understanding of complex biological systems and their design via genome and pathway engineering. It is to be leading tools to the next wave of revolution in agriculture, when coupled with unprecedented computational capabilities that enable one to connect genotypes to phenotypes, and emerging tools for precise reprogramming of plant genomes and epigenomes, plant genome editing is an unparalleled evolution in plant biotechnology. In addition, CRISPR-Cas brings new challenges that many plant species and genotypes are recalcitrant to regeneration and/or transformation, CRISPR-Cas reagents delivery systems need to be improved, need to be addressed before genome editing technology is fully realized as a precision plant breeding tool. It has bright future for genome editing in plant synthetic biology and domestication, advances in delivery systems, editing specificity, homology-directed repair, and gene drives. This technology can be expected to have an ever increasing impact on crop improvement as we approach the new millennium.

Ms Suveditha SImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICAR- IIHR


Surveys of virus and virus like diseases were conducted in cucurbit growing regions of Karnataka,Andhra Pradesh, Tamil Nadu and Rajasthan. The symptoms in ridge gourd included interveinalchlorosis, green vein banding and thickening of younger leaves while older leaves showed chloroticpatches or complete yellowing and downward rolling of leaves, varied between 5 to 25% and resembledsymptoms caused by Polerovirus. The symptomatic samples collected from field were washed withRNase-free sterile distilled water and leaf dip preparations were examined under an electronmicroscope which showed presence of isometric particles. Total RNA extract obtained from symptomaticand healthy leaf samples of ridge gourd were used for RT-PCR and PCR amplification using polerovirusgeneric primers. The results have shown amplification of 350bp DNA fragment from infected samplesbut not from healthy control plant samples. Cloning, sequencing and nucleotide blast search showed95-97% % similarity with poleroviruses and more than 93% with Cucurbit- aphid borne yellows virus(CABYV) (Genus: Poleroviruses; Family: Luteoviridae). This is the first report of the occurrence ofCABYV in ridge gourd in India. The high frequency with which CABYV was detected in the samplesindicates that the virus is an important and emerging virus infecting cucurbits in India suggestingthat it should be taken into account in disease control of cucurbit crops in India.

Ms Ruchi SharmaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Shoolini

University, SolanDesignation : Ph.D Food

Technology student

In the present study, low-calorie kinnow based herbal beverage was formulated using different concentrations of mint, ginger and giloy. Kinnow a citrus fruit is a hybrid of Citrus nobilis and Citrus deliciosa. The polyphenols like hesperidin, vitamin C, carotenoid, naringin, and cyanidin glucoside are effective in boosting the immune system against various heart diseases. The mint leaf is useful in the treatment of gastrointestinal disorders. Ginger possesses anti-inflammatory activities due to its bioactive compounds and reduces cholesterol levels. Giloy carries anti-inflammatory activities which are helpful in building up the immune system. Different blends of kinnow juice and herbs were taken for the development of beverage. On the basis of sensory characteristics, the treatment prepared with kinnow: mint: ginger: giloy in the ratio of (10:1:3:1) was selected for further development of low-calorie beverage by replacing sucrose with stevia at different levels of 0, 70 and 100%. Addition of 70% stevia and 70% sugar as low-calorie sweeteners increase the acceptability of kinnow based herbal beverage on the basis of sensory attributes. It also showed lower content of total and reducing sugars. The beverage stored at refrigerated (4-7ºC) conditions was found highly acceptable as compared to beverage stored at ambient (27?C) conditions. However, with an increase in storage period up to 60 days a decrease in pH and ascorbic acid and an increase in TSS, titratable acidity, total sugar and reducing sugar content was observed. The energy value of low-calorie kinnow based herbal beverage was 27.48 Kcal/100 ml as compared to the beverage prepared by using sugar 51.6 Kcal /100ml. Therefore, the present investigation emphasized that low-calorie herbal kinnow based beverage can be prepared using stevia which enhances the immune system and can be consumed by diabetic patients due to the presence of low-calorie sweetener stevia. Keywords: - Kinnow, mint, giloy, herbal, beverage, stevia.

Ms Khyati OberioImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Shoolini University Solan, (H.P)


Banana (Musa acuminate) is one of the most important commercial fruits. It contains various vitamin and has therapeutic uses. Banana is very popular to the human diet due to its high nutritional value. Post-harvest losses during harvesting and storage are quite high because of its perishable nature. Therefore, to avoid losses, one of the methods to increase shelf life is drying. Among the various preservation methods, drying is the most convenient and simple method which causes a reduction in water activity of food products. Osmotic dehydration provides high-quality products by removal of water without the phase change.. The present study is carried out to develop novel product osmo-dried banana slices and choco shots. Banana slices were osmosed with sugar solution and honey of 72 ºBrix for 3 hours and then cabinet dried. The osmo-dried products were packed in PET jars stored at room temperature. The quality in terms of nutritional and sensory was evaluated at fresh stage and during storage at an interval of 0-60 days. Changes were observed during storage at room temperature. Honey osmodried banana slices were found better in terms of sensory and quality characteristics and have less water activity. Novel product i.e. banana choco shots were also prepared from osmo-dried banana slices. The protein content of banana choco shots from sugar and honey osmo-dried banana slices were 5.74 and 5.78. From the storage study, it was found that the banana choco shots packed in PET jars can be stored up to 30 days without minimum changes in the quality. Thus, the developed technology can be commercially explored at the industry level for the production of value-added products like banana choco shots for efficient and profitable utilization of this fruit for ensuring better returns to the grower. Key words: banana, choco shots, nutritional, osmotic dehydration, storage, slices.

Mr MD SALMAN HAYDARImage Delegate ID Theme Details


Research


North BengalDesignation : Research

Scholar

Investigating the nano-bio interaction pattern for safe use of nanoparticles to any biologicalsystem is a challenging job. However recently use of nanoparticles is increasing in various field ofapplication, out of which agriculture holds an important position. Mulberry is an importantagricultural crop, serving as a sole food for monophagous insect silkworm larvae, the product ofwhich (raw silk) puts impact on economy of our country. Mulberry plant undergoes vegetativepropagation and under normal condition it requires longer time for the appearance of first leaves.Our study mainly emphasizes on enhancing the sprouting percentage, decreasing the duration of leafappearance and improving the overall vigour of mulberry cultivar (S1) by application ofphytosynthesized iron nanoparticles (FeNPs) and its EDTA functionalized form. FeNPs was synthesizedfrom FeCl3 by using Camellia sinensis leaves extract. Formed nanoparticles were characterizedthrough UV-visible spectra, SEM, TEM, EDX, XRD, FTIR and DLS. Application of nano iron was doneinitially by direct application in sterilized soil in the ratio of 1:100 and 5:100 and later byfoliar spray. Our result suggests that tea leaves act as an effective reducing and capping agent asrevealed by different spectrometric and image profiling. In mulberry propagation, an alternativenutrient source has been found which significantly improve vigor index as well as differentbiochemical and enzymological parameters of the treated plants at their optimized concentrationsthan normal iron salt.

Mr RAM PRASAD SAHUImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NATIONAL INSTITUTE OF SCIENCE

EDUCATION AND RESEARCH


ROLE OF TRPV3 IN NUCLEOLAR FUNCTIONS Ram Prasad Sahu* Chandan Goswami PhD Scholar, [email protected], Associate Professor, [email protected] [email protected] TRP (Transient Receptor Potential) channels are non-selective cationic channel and are important for several physiological functions. In human, there are 28 members of TRP ion channels. These are classified into two broad groups based on the sequence and topological differences: group 1 includes TRPC (“C” for canonical), TRPV (“V” for vanniloid), TRPM ( “M” for melastatin), TRPN and TRPA. In group 2 there are TRPP (“P” for polycystic) and TRPML (“ML” for mucolipin). These channels are known to be activated by various endogenous compounds, pharmacological compounds and as well as by different physical stimuli such as temperature, osmolarity etc. TRPV3 is a thermosensitive channel, is involved in Ca2+-signaling and different cellular functions. Previously it was believed that these channels are expressed in peripheral neurons primarily and are restricted to the plasma membrane only. Recently reports suggest that this channel is also involved in the regulation of keratinocytes, immune cell functions and it localizes to sub-cellular organelle like ER, lysosomes as well. Here we show that apart from different subcellular localization of TRPV3, it also localizes to the nucleus. In macrophage cells, TRPV3-specific immunoreactivity is observed in the nucleus, especially after macrophage activation by LPS. Accordingly, we have identified a NLS motif present in human TRPV3. In accordance, only NLS-fused with GFP localizes to the nucleus and become enriched at the nucleolar region. We demonstrate that this NLS motif is not conserved in all vertebrates, rather more specific for mammals only and not present in other vertebrates (with some rare exceptions). This may also suggest that TRPV3-mediated regulation of nucleus can be an event recent in the phylogenetic tree. However, detailed functional significance of such nuclear localization need to be explored in future.

Dr Ruchi YadavImage Delegate ID Theme Details


Research


University Uttar Pradesh, Lucknow Campus, Lucknow


Abstract: NPAS3 (Neuronal PAS Domain Protein 3) is a member of PAS domain containing helix-loop-helix motif and belong to PAS superfamily. NPAS3 gene is mainly expressed in human brain but its function is still unclear. NPAS3 gene is associated with neuronal development disorder. It encodes transcription factor that have wide function in neurogenesis, synapse activity, hypoxia, metabolism of toxic compounds etc. Although the importance of NPAS3 protein has been widely studied in neuronal disorders like schizophrenia and cognitive disability, the structural and functional characterization id not well understood. In current study I have performed the structure prediction, binding site prediction, disorder region, phylogenetic analysis, protein interaction, functional and pathway analysis by using different in-silico tools and databases. Structure prediction and binding site prediction was done by Schrodinger software and verification was done by Ramachandran plot and Q-mean analysis, protein characterization was done by MobiDB, phylogenetic analysis was done using MUSCLE software, protein interaction was done using STRING and GENEMANIA, Functional and pathway analysis was done using Gene Ontology Database and KEGG database. The result shows that NPAS3 protein have function in forebrain development (GO: 0030900 ) and forebrain ventricular zone progenitor cell division (GO: 0021869) by similarity with POU3F protein. Pathway study shows that NPAS3 protein belongs to renal cell carcinoma (hsa05211), HIF-1 signaling pathway (hsa04066) by similarity. Phylogenetic analysis predicts that NPAS3 protein has evolution from Chrysochloris asiatica. Protein interaction study identifies that NPAS3 protein have interaction with ARNT2, POU3F3,TCEB1, CREBBP, CASK, EP300 and POU3F1 this confirms that this protein have function in embryonic development and involved in neurodevelopment. This study provides the complete annotation of NPAS3 protein which can be further used to study its mechanism in neurodevelopmental disorders. Keywords: NPAS3, PAS Domain, STRING, embryonic development, neurodevelopmental disorders

Dr Mamatha Bhanu LSImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Yuvaraja's

college, University of MysoreDesignation : Assistant

Professor

The unique components of colostrum like free oligosaccharides and glycoconjugates are known to offerresistance to enzymatic digestion in the gastrointestinal tract and have the ability to inhibit thelocalized adherence of enteropathogens to the digestive tract of the neonates. In this context, wehave evaluated the in vitro effect of buffalo colostrum immunoglobulin G on human pathogenKlebsiella pneumoniae, a predominant multidrug resistant pathogen associated with nasocomialinfections. The investigation revealed growth inhibitory potential of immunoglobulin G in a dosedependent manner supported by scanning electron microscopic studies. The N-glycan enriched fractionof immunoglobulin G after PNGase treatment was found more effective, comparable to ampicillin thannative immunoglobulin G supporting the fact that colostrum derived oligosaccharides is crucial andact as ideal substrates for undesirable and pathogenic bacteria. The MALDI TOF/TOF analysisconfirmed the glycostructures of abundant N-glycans of immunoglobulin G exerting antibacterialactivity. The proteomic analysis revealed variations between control and treated cells andexpression of chemotaxsis - CheY protein (14kDa) was evidenced in response to immunoglobulin Gtreatment. Hence, it would be interesting to investigate the mode of inhibition ofmultidrug-resistant Klebsiella pneumoniae by buffalo colostrum immunoglobulin G with theidentification of a newly expressed signalling protein.

Mr Neeraj Kumar RaiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Central University of South BiharDesignation : Research

Scholar

In the last few decades several reports have suggested that mitochondrial functional changes are critical factors in cancer initiation, progression and metastasis. Some of these changes include mtDNA mutations, mtDNA copy number changes, oxidative stress and metabolic reprogramming which are now frequently observed in various cancer. However their specific mechanism in cancer progression is still unclear. In this preliminary study, we utilized cellular models of colon cancer and investigated the effect of mitochondrial RC inhibition on cancer cell survival. Among different RC inhibitors, we found that compared with normal cells, low and high metastatic colon cancer cells were resistant to complex I inhibitors. Further we found that CI assembly as well as C-I activity are significantly reduced in cancer cells as determined by Blue Native Gel Electrophoresis (BN-PAGE) and in gel activity respectively. As a result, mitochondrial functions such as ATP levels and membrane potential were decreased and Reactive Oxygen Species (ROS) were significantly enhanced compared to normal cells. Results on mt-DNA copy number variation show lower mtDNA copy number in metastatic cells suggesting a decrease in mitochondrial numbers possibly due to C-I impairments. These initial results suggest that mitochondrial complex I is significantly compromised in metastatic colon cancer cells and resistant to mitochondrial oxidative stress possibly originated through C-I inhibition. We also found that complex I alterations cause activation of specific oncogenic signaling pathway. Further studies are aimed to identify the role of C-I alterations in metastatic progression through Cybrid system. Results from these studies will provide novel mechanistic links related to mitochondrial dysfunction and its contribution in cancer progression that would be useful to develop mitochondrial targeted therapeutic approaches for cancer treatment.

Ms Archana BhatImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : School of

Biotechnology, University of Jammu.

Designation : Senior Research Scholar

Crocus sativus is a triploid (2n=3x=24), sterile (seedless) geophyte propagated by corms and thuslacks genetic variability. It has a large (~ 30000 Mb) genome, making it less amenable to geneticmanipulation. Dried stigmas of this plant constitute the Saffron of commerce. Iran is the largestproducer of Saffron (80%) in the world. In India, saffron is grown only in the state of Jammu andKashmir and is known for its good quality. Saffron is the highest priced spice in the world. It is arich source of apocarotenoids, namely crocetin, crocin, picrocrocin and safranal which havingtherapeutic applications. Understanding the regulation of various genes involved in theapocarotenoid biosynthetic pathway can result in an approach to engineer this pathway to increasethe accumulation of these bioactive compounds. The bottlenecks in this direction are the sterilityand genome complexity of Saffron. To achieve the desired objectives, I have isolated the promotersof two genes of the apocarotenoid biosynthetic pathway namely CsPSY and CsUGT by using GenomeWalking technique. Functional validation of these promoters was performed in homologous (Crocuscalli) and heterologous (Tobacco) systems using GUS reporter vector system and Agrobacteriummediated transformation. Response of various phytohormones (Gibberellic acid and Abscisic acid) onthe activity of these promoters was studied based on the presence of their response elements in thepromoters. Real Time expression analysis of some apocarotenoid specific genes (CsPSY and CsUGT) andvarious stigma specific transcription factors (23 TFs) upon treatment with these phytohormones wasalso studied. It was concluded that the GA enhances the activity of CsUGT promoter while as ABAenhances the activity of CsPSY promoter. Among 23 transcription factors, CsAUX, CsbHLH, CsARF,CsMYB, CsWRKY, and CsSNF showed significant modulation in expression in both GA and ABA treatedflowers but was comparatively higher in GA treated flowers.

Dr Rupesh K. SrivastavaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : All India

Institute of Medical SciencesDesignation : Assistant

Professor

Dietary Salt intake and Bone Health: Role of Immune System

Rupesh K. Srivastava1* 1Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi-110029, India

*[email protected]

Introduction: Osteoporosis depicts bones with reduced bone density and quality, leading to high risk fractures with higher incidences of mortality and morbidity. Lately, preferences for western foods with higher salt content has increased the occurrences of various inflammatory diseases to many folds. One of the main reasons for these higher incidences is promotion of pathogenic Th17 cells and impairment of Treg cells. Increased Th17 cells have been already associated with various bone pathologies including osteoporosis.

Material & Methods: 30 male mice of 8-10 weeks’ age were divided equally into three groups as Normal (0.8% NaCl), Low salt diet (0.4% NaCl) and High salt diet (HSD) (4% NaCl). At the end of 45th day, mice were sacrificed for harvesting different tissues and organs to elucidate the role of HSD intake on bone health by using various cutting technologies such as, AFM, SEM, ?CT, FACS, FTIR, ELISA and in vitro osteoclast culture assays.

Results: Our results for the first time reported that HSD leads to enhanced bone loss in male mice. This was validated by various bone histomorphometric parameters and reduced bone mineral density (tibia & femur) along with reduced heterogeneity of bones. Our results also showed that HSD intake modulates host immunity leading to higher proportion of osteoclastogenic Th17 cells along with reduction of anti-osteoclastogenic Treg cells. Interestingly, HSD depresses various anti-inflammatory cytokine levels (IL-10, IFN-G) and enhances proinflammatory cytokine levels (IL-6, IL-17 and TNF-a) in male mice.

Conclusion: Altogether, our study was first to elucidate the role of HSD in augmenting Treg-Th17 cell balance by enhancing Th17 cell production with simultaneous decrease of Treg cells thereby leading to enhanced inflammatory bone loss.

Dr Subhabrata PaulImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Presidency

University, KolkataDesignation : Assistant

Professor

With gradual loss of agricultural land in one hand and increasing global population on the other,the main challenge of today is to ensure food for everyone. Half of the world’s population dependson rice as a source of major staple food,so improving the yield and quality of rice is necessary forfood security. In the present study, a novel technique termed as pulsing, which is a modification ofpriming, has been used to treat rice seeds for 72 hours. Iron is considered as an importantmicronutrient and one of the key elements in regulating plant growth and development. Iron pulsingfor 72 hours during initial phase of germination proved to be effective in increasing thegermination percentage and the hydrolytic enzyme activities.A critical biochemical and molecularinvestigation revealed that, 14 day old seedlings showed enhanced vigor, better photosynthetic rateand improved nitrogen assimilation. All these translated to improved yield when treated plants weretransplanted in the field, showing more grain per plant.

Mr Yashwant Kumar RatreImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Guru Ghasidas

VishwavidhyalayaDesignation : Research Scholar

Abstract Diabetes and cancer are severe chronic diseases massively affecting the world’s population. The considerable number of studies suggested the predictive role of diabetes and other clinical profile in the prognosis of many types of cancer, but its role in prognosticating cervical cancer is still controversial. We aimed to evaluate the association of diabetes and clinically related parameters with cervical cancer patients. In this hospital based case-control study, whole blood sample was collected from cervical cancer patients (n=100) and age matched healthy volunteer (n=100) to estimate the frequency of diabetes and related clinical parameters by using respective analytical techniques followed by statistical analysis. In this study, we noted that the frequency of diabetes in cervical cancer patients (45%) was significantly (p

Dr Zahra IqbalImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-National

Botanical Research InstituteDesignation : Senior

Research Fellow

Differential expression of pH dependent polyphenol oxidase in Capsicum annuum L. Zahra Iqbal Department of Botany, University of Lucknow, Lucknow-226007, India

The activity of enzyme can be influenced by the nature of the buffer used. The effect of pH is usually experimented at higher substrate concentration. In the present study effect of pH change was observed on the enzymatic activity of Capsicum annuum L extract. Polyphenol oxidase was observed by oxidizing catechol (as substrate) and forming benzoquinone. It was noted that maximum activity was observed with enzyme isolated at pH 8.8 and activity taken at pH 7.0 with (3.7404± 0.3399 nanokatal). While minimum was observed with enzyme isolated at pH 6.8 and activity taken at pH 4.5 with (0.4803±0.04846 nanokatal). When activity staining of 10% native PAGE gel was done using catechol as substrate it was observed that different isoforms was found at different pH of buffers used. Maximum 6 isoforms was observed at pH 7.0 and pH 8.8 while only 2 isoforms were observed at acidic pH 4.5 and pH 6.0. It can be concluded that pH optima for polyphenol oxidase in Capsicum annuum L. have been accounted between pH 4.5 and 8.8. It must also be taken into account that the optimum pH can also be affected by the purity of enzyme and the type of buffer used. It is imperative to mention here that role of isoforms detected at different extraction and activity pH would be of immense academic and mechanistic significance. Keywords: Capsicum annuum, enzyme, polyphenol oxidase, PAGE.

Dr Sudhir VermaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Deen Dayal

Upadhyaya CollegeDesignation : Assistant

Professor

The ever-increasing demand of unconventional or alternative feed supplements for aquaculture has enhanced the interest in investigating microorganisms as a potential source, In recent past. The microbes of interest include zooplanktons, algae, fungi and the bacteria. Bacteria being cosmopolitan in distribution can be found in freshwater, marine water and waste-water systems. In the present study, bacteria collected from different marine ecosystems were characterized in terms of their biochemical composition in order to obtain alternative feed supplements for aquaculture. The marine ecosystems include Sand dunes, Mangroves, Rocky shores and saltpans which were located respectively at Miramar (15°.487ºN, 73.8074ºE), Salim Ali Bird Sanctuary (15°.5152ºN, 73.8565ºE), Cacra Beach (15º26’59.66N, 73°50’19.76 E) and Ribander (15.5005 ºN, 73.8691 ºE), Goa, India. The collected soil samples were grown on different culture media under various physical conditions. The obtained pure bacterial strains were further analyzed using hydrogen peroxide plate assay to isolate PUFA positive strains. The proximate composition of PUFA positive bacterial strains was obtained in terms of Crude protein, Total Carbohydrate, Total Lipid, Moisture and Ash content using standard methods. Further, antioxidant properties of these bacterial strains were analyzed using catalase enzyme assay, levels of reduced glutathione and Vitamins (Vitamin C, E, B2 and B7). Also, lipid profiling was done by estimating glycolipids, phospholipids, cholesterol and triglycerides. Based on the biochemical composition, the feed can be prepared for aquaculture using the selected PUFA-positive bacterial strains which can serve as an alternative/ unconventional feed supplement with batter nutrients and antioxidant properties. The present work was jointly supported by Science Academies' Summer Research Fellowship.

Ms Amrita MukherjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bose Institute

Designation : SRF

Lack of crops to feed the growing human population and crop loss due to different kinds of bioticand abiotic stresses is constantly posing a threat to food security globally. In this connection,enhancement of edible oil production through increasing production of oilseed mustard is of greatimportance in crop improvement. Throughout the world, oilseed mustard, which includes Brassicajuncea, Brassica rapa, Brassica napus is considered as one of the major sources of edible oil.Brassica juncea is a potential target of the devastating necrotrophic fungus Alternariabrassicicola. Every year this crop suffers a 10-70% yield reduction due to this pathogen.Non-availability of resistance germplasm in B.juncea against A.brassicicola and non-availability ofB.juncea mutant lines make the study on the resistance-susceptibility mechanism of this plant verydifficult. Two non-host plants, Sinapis alba, and Arabidopsis thaliana, belonging to the sameBrassicaceae family as B.juncea show resistance against this plant. Hormonal pathways studies andmutant analysis of Arabidopsis have proved the role of various phytohormones in resistant againstthis pathogen. Auxin, abscisic acid, and jasmonic acid are the major players against necrotrophicpathogens in Arabidopsis and S.alba. Auxin response factors (ARF) which connects ABA and auxinresponse are an important area of research. Three ARFs, ARF10, ARF16 and ARF17 have been found to beupregulated in S.alba whereas it remained downregulated in B.juncea upon challenge with thepathogen. As ARF10 was upregulated in all the time points, it was conditionally expressed under theGH3.3 promoter taken from B.juncea. GH3.3 promoter was found to be induced by salicylic acid,A.brassicicola, and auxin whereas it was not induced by ABA. Transgenic B.juncea plantsconditionally expressing ARF10 exhibited elevated expression ABA-responsive genes like ABI3, ABI4,and ABI5 while the expression of auxin biosynthetic genes were not changed upon pathogen challenge.Induced ABA sensitivity caused by conditional expression of ARF10 in transgenic B. juncea resultedin tolerance against A. brassicicola along with phenotypic changes like stunted growth, reduced seedsize, altered root length, and late seed germination. Through in vitro DNA-protein experiments andchromosome immunoprecipitation using the ARF10 antibody, we demonstrated that ARF10 interacts withupstream auxin-responsive elements of ABI5 promoter. This suggests that ARF10 may function as amodulator of ABI5 to induce ABA sensitivity and mediate the resistance response against A.brassicicola.

Dr Anil KumarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : National Institute of Immunology

Designation : Staff Scientist

The fourth most common cancer in the world is Colorectal Cancer and each year 1.3 million new casescan be seen throughout the world. It is estimated that there were around 7.0 lakhs death due tocolorectal cancer (CRC) in 2012 globally. Considering USA and India, incidence is higher in males inboth countries but mortality, and prevalence rates are all consistently higher in the USA. In India,it is the fifth most common cancer following breast, cervical, oral, and lung cancer. The gutmicrobiota is considered as a forgotten organ in human health and disease. It maintains guthomeostasis by various complex mechanisms. The dysbiosis or disruption of gut flora has beenconfirmed to be related to gastrointestinal diseases such as CRC and other diseases in differentorgans. Colorectal cancer is a multi-factorial and multi-stage involved disorder. The role formicroorganisms that initiate and facilitate the process of colorectal cancer has become clear. Ourgroup is studying the link of gut microbes in colorectal cancer causation. Clearly, more informationis needed about mechanisms through which the microbial community promotes carcinogenesis.Understanding the events leading to development of intestinal carcinogenesis through gut microbeswill provide novel insight into this pathology, and potentially lead to new therapeutic modalitiestargeting the microbiota.

Dr Biplab BagchiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bangabasi

CollegeDesignation : Asst.Professor

Abstract: Fungal endophytes from Bauhinia vahlii were studied collecting from Belpahari of Jhargramdistrict of West Bengal during three seasons-winter, summer and monsoon. leaf, stem and petiolesamples each of 1 cm was put in agar media for isolation of fungal mycelia, and the mycelia were putin PDA media for huge growth of mycelia and reproductive parts. In the study 159 tissue segments outof 225 were infested by fungal endophytes and 201 fungal members were isolated. The fungal isolatesbelong to the genera as many as 25, along with 5 unidentified fungi and few sterile mycelia.Beltrania sp., Lasiodiplodia sp., Fusarium sp., Penicillium sp., Pestalotiopsis sp. were mostcommonly and dominantly found. Majority of the endophytic isolates was in monsoon and least insummer. Colonization frequencies in leaf, stem and petiole in three seasons are72%, 70.66% and69.33% respectively. It is clear that fungal assemblage is the lowest in petiolar parts. Colonization frequency in three seasons are as follows-monsoon78.66%> winter73.33%> summer60%.Maximum were under the class Sordariomycetes and Deuteromycetes, imperfecti fungi were screened.This difference in CF % might be due to variation of moisture content in various seasons inside itand variation of absorvable nutrient contents in forest floor. The infection and colonization ofleaves and stems by endophytic fungi are affected by biotic and abiotic factors. Heterogeneity inthe factors of physical microenvironments like intensity of sunlight, temperature and moisture,which can lead to morphological variations in physical and chemical characteristics of foliarleaves, is expected to in?uence the colonization frequency of endophytic fungi. Frequency ofoccurrence of endophytes was highest in monsoon, which slightly decreased in winter, decreasedfurther in summer. It might be presumed that the transient reduction of endophytic fungi in drysummer might be due to lower rate of reproduction and death hot and drought conditions and bydefence responses of the plant host. So, It can be concluded that microenvironment and microclimatewere determining factors for assuring endophytic biodiversity.

Ms Ankita DasImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : IIEST


Stem cells are endorsed with indefinite cell division potential which can transdifferentiate intoother types of cells, and therefore, have emerged as frontline regenerative medicine source inrecent time. A fine balance between these cell division processes are achieved through controlledsymmetric and asymmetric divisions, necessary to generate cellular diversity during development andto maintain adult tissue homeostasis. Disruption of this balance may result in premature depletionof the stem/progenitor cell pool. From a tissue-engineering perspective, the proper choice ofsymmetric or asymmetric division for stem cells is crucial. Symmetric and asymmetric cell divisionis not mutually exclusive and a range of factors both intrinsic and extrinsic are involved in suchcell-fate decisions, the measurement of which can provide efficient and reliable information on theregenerative potential of a cell. The balance between self-renewal and differentiation in stem cellsis controlled by various biophysical and biochemical cues. The effect of biophysical cues instem-cell self-renewal and asymmetric stem cell division is not comprehensively understood.Biophysical cues can be surface topological differences, electrical stimulation, magnetic field,micropatterning, matrix stiffness etc. Extracellular matrix (ECM) provides a dynamicmicroenvironment to the cell and by modulating the ECM in vitro, a varied stem cell niche can becreated. In this study, by using stiffness variation in solvent-casted PCL membrane as a biophysicalcue in the regulation of stem cell division pattern, the importance of umbilical cord derivedmesenchymal stem cell symmetric: asymmetric pool maintenance along with its relation with cellularpolarity and mechanotransduction pathway has been reported. It has been found that with increasingmembrane stiffness, the fate of the cell tends more towards asymmetric cell division implyingbiological relevance of increased transdifferentiation rate which is an important aspect forsuccessful stem cell therapy in regenerative medicine.

Dr Somsubhra NathImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Saroj Gupta

Cancer Centre and Research Institute


Chronic myeloid leukemia (CML) is a genetic disorder of hematopoietic stem cells, where atranslocation between BCR gene in chromosome 22 and ABL gene in chromosome 9 acts as the hallmark ofthis disease. The resultant BCR-ABL fusion transcript, termed as Philadelphia chromosome, confersconstitutive tyrosine kinase activity facilitating uncontrolled cellular growth. Interestingly, withthe advent of tyrosine kinase inhibitor (TKI) therapy, the management of this disease experienced aparadigm shift. Nonetheless, the development of resistance against the drug posed a serious threat.Simultaneously, several point mutations in the kinase domain of BCR-ABL transcript were detected toconfer this resistance. However, this mutational landscape in conferring TKI drug resistance and theresultant molecular phenotypes remain elusive in Eastern-Indian cohort of CML affected individuals.In this study, we recruited 25 clinically confirmed TKI drug resistant CML subjects, upon theirsigned consent. Phenotypic analysis revealed that majority of this study cohort developed acquiredresistance against the drug in chronic phase of disease. Further, to investigate the molecularnature of this translocation, we found that, in majority cases, the fusion lies between exon 14 ofBCR and exon 2 of ABL. Moreover, in all the study subjects, the BCR-ABL% ratio, as determined byquantitative real-time polymerase chain reaction, showed a value above 0.1%, confirming themolecular parameter of drug resistance. Finally, we employed targeted deep sequencing technology toexamine the mutational landscape of the kinase domain of BCR-ABL, along with conventional Sangersequencing based application. Interestingly, deep sequencing could detect a few additionalclinically significant mutations, occurring at low frequencies, which otherwise not detected by theSanger technology. This, particularly, helped in obtaining the mutational profile in a few affectedindividuals, where Sanger method failed to provide any relevant information, making the clinicaldecision a difficult one towards the disease management upon TKI-resistance.

Dr PARIMALAN RANGANImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICAR-NBPGR


Wheat is one of the three important cereal crops that feeds the global population and istaxonomically classified under sub-family Pooideae, commonly known as ‘cool-season grasses’. Being a cool-season crop, it is very sensitive to high temperature stress. In addition, climatechange factors with the harsher environmental conditions directs a significant impact on the yieldsustainably. This highlights the importance of identifying the genotypes that are tolerant to hightemperature and the requirement to understand the molecular networks occurring in plants impartingtolerance. To address this, tolerant (Fang-60) and susceptible (Banks and EGA Gregory) wheatgenotypes were subjected to heat stress in triplicates at 38oC/20oC (12/12-hour) for three daysduring early (11-14dpa) and late (27-30dpa) grain filling. Developing spikes from control and heatstressed plants were harvested, snap frozen using LN2, isolated developing grains and pulverized forRNA extraction. These RNA samples were sequenced using Illumina’s Hi-Seq 4000 for differentialexpression studies with cDNA dataset of IWGSC-2018 as reference using CLC genomics workbenchv11.0.1. The list of genes that are statistically significantly differentially expressed at FDRcut-off value of 0.01 were identified and subjected to functional annotation studies using OmicsBoxv1.1.78. Differential gene expression studies followed by functional annotation approach helpedunderscore the network of genes that are statistically significantly differentially expressedspecifically in tolerant genotype than susceptible genotypes, that helped successfully accomplishsustained grain-filling in tolerant one. Conversely, few genes that are differentially expressedduring heat stress specifically in susceptible genotypes, adds to the problem of failure inexpression of required genes (identified in tolerant genotypes) resulting in poor grain filling. Inaddition, the list of genes that are heat stress responsive – significantly differentiallyexpressed across all the three genotypes studied were identified, and its link further downstream onmolecular regulation in tolerant genotype needs to be established.

Ms Arundhati MehtaImage Delegate ID Theme Details


Research


Vishwavidyalaya (A Central University)


Arundhati Mehta, Vivek Kumar Soni, Naveen Kumar Vishvakarma*, Dhananjay Shukla Department of Biotechnology Guru Ghasidas Vishwavidyalaya (A Central University) Koni, Bilaspur, Chhattisgarh, 495009 *E-mail: [email protected]

Due to the unpleasant effect of standard drugs, the neoteric strategies encompass phyto-molecules for therapy. Eugenol (EUG), an allylbenzene compound extracted from Syzygium aromaticum (Clove) has been reported for anticancer activity against cells of various etiologies. However, the underlying mechanism will help in designing strategies with translational potential. The current investigation assessed the anti-neoplastic activity of EUG against lymphoma cells and altered cell growth-kinetics as mechanism along with in-silico prediction of ability to modulate regulators of angiogenesis and altered redox status. Viability and growth kinetics were enumerated for EUG-treated Murine-lymphoma (Daltons Lymphoma) cells. Molecular Docking of EUG with ligand-binding [4KZN] & Kinase [1VR2] domain of VEGF-R, VEGF-A/VEGF-R2 Complex [3V2A] and Akt [1O6L] were performed using Moe2008.10 software. Biochemical Pathway Simulation of Mitochondrial Oxidative Stress ODE Model was run to check Time-Course of FoxO3a expression using COPASI-software. A concentration dependent decline in cell survival, augmented cell population undergoing death and inhibition of growth-kinetics was observed in EUG-treated cells along with Pyknosis and reduced cellular size. Predictive high binding-affinity [E-score -10.3975] with VEGFA/VEGF-R2 complex was observed. Nevertheless, low E-scores [-13.254 & -14.5676] were predicted for interaction of EUG with ligand-binding and kinase domain of VEGF-R2, respectively. Simulation analysis divulged the inhibition of AKT along with FoxO3a activation in a time-course manner. EUG restricts the growth of cells by modulating growth-kinetics. Predictive in-silico analysis suggests, the inhibition of angiogenesis through competition with VEGF for binding with VEGF-R as well as their inhibition of signal transduction and modulation of redox-status. All these effects may culminate in limiting growth and division of neoplastic cells. These finding with further analysis pave the path for potential designing of anticancer strategies using EUG alone or in combination.

Reference:

1. Bezerra, D.P.; Militão, G.C.G.; De Morais, M.C. and De Sousa, D.P., Nutrients. 2017, 9(12), p.1367. 2. Mallick, S.K.; Gupta, V.; Singh, M.P.; Vishvakarma, N.K.; Singh, N. and Singh, S.M., Orient Pharm Exp Med. 2008. 7(5), pp.459-465.

Mr Shivmurat YadavImage Delegate ID Theme Details


Research


Institute of Medical SciencesDesignation : Ph.D.

Abstract Calcium is one of the important factors determining the bone mineral density (BMD) and hence low calcium intake deteriorates bone micro-architecture 1 and decreases the bone mass and longitudinal growth 2of animal. While the other hand high calcium intake increases the BMD in both growing animal and children. Bone modeling is an important period of bone growth in growing animal and dietary calcium inadequacy in this period may lead to severe bone damage. Reversibility associated with bone micro-architecture damage due to calcium deficiency in the modeling period is still not clear. In this study, we induced dietary calcium deficiency in growing female Sprague-Dawley rat and checked its reversibility after high calcium replenishment employing the techniques- micro-computed tomography (micro-CT) and dynamic histomorphometry. Our result showed that calcium deficiency in growing animal significantly decreases the trabecular and cortical bone micro-architecture and BMD due to secondary hyperparathyroidism. Reversibility by feeding calcium replenishment diet to calcium deficient rat revealed that there was an improvement in bone micro-architecture and BMD. However, improvement in trabecular bone was partial while the improvement in cortical bone was complete. Dynamic histomorphometric analysis showed that partial recovery in the trabecular region of bone was due to lower the rate of bone formation (BFR) and bone mineralization (BMR). Recovery result showed that despite the recovery in biochemical markers associated with the calcium homeostasis, cortical micro-architecture and bone BMD, the trabecular bone micro-architecture was still compromised due to under mineralization of bone. Our result clearly demonstrated that dietary calcium sufficiency is crucial for proper bone mineralization, modeling, healthy bone micro-architecture and optimum bone growth in the growing animals. Keywords: Calcium deficiency, BMD, bone micro-architecture, dynamic histomorphometry

Dr Dhiraj VyasImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dr.CSIR-IIIM

Designation : Principal Scientist

In brassicales, the glucosinolate-myrosinase system plays an important role during insectinteractions. Given the multifunctionality of glutathione and its involvement during glucosinolatebiosynthesis, it is hypothesized that the two might exist as part of the adaptive regulatorymechanism during biotic interactions. For understanding their dynamic equilibrium, a high altitudeplant Lepidium latifolium L. growing in Ladakh was selected that was earlier shown to have robustglutathione homeostasis. It was observed that the differential accumulation of glucosinolatescorroborated with the GSH/GSSG ratios more than the metabolic content of glutathione alone. Lepidiumlatifolium was grown in Jammu and different insect interaction stages based on oviposition data ofPieris brassicae were characterized. Results suggest that the reducing conditions, where theGSH/GSSG ratio was higher, results in the higher accumulation of the indolic/aromatic glucosinolates(IGLS). The expression analysis suggests that these effects are mainly under the transcriptionalregulation of MYB51 and MYB122. Further, the GSH/GSSG ratios were modulated using differentconcentrations of GSH, BSO, DTT, H2O2, MJ, and SA during in vitro and in vivo experiments. GSH andMJ increased the GSH/GSSG ratio and the IGLS, which in turn increased the herbivory by Pierisbrassicae larvae in both choice and non-choice bioassays. The larvae did not prefer treatments wherethe GSH/GSSH ratio decreased. The hypothesis was validated on another plant and insect species. Aredox-regulated glucosinolate hydrolyzing enzyme, myrosinase, was also characterized. In conclusion,a putative role of redox in the glucosinolate-myrosinase system was observed that results indifferential biotic interactions in the subtropical region.

Dr TANUSHREE AGARWALImage Delegate ID Theme Details


Research


CalcuttaDesignation : Post Doctorate

Scholar

Agriculture in India is mostly unorganized and dependent on natural weather cycles rather than usage of modern technologies. Farmers depend heavily on the rain gods and unpredictable weather cycles often cause largescale crop failures due to drought leading to bouts of famine. Add to this, other stress factors such as pests and crop diseases puts tremendous pressure on farmers and their families. In the recent past, this has also led to extreme measures among farmers including suicides and the situation does not seem to be improving. There are approximately 126 research institutes involved in the field of Biological and Agricultural Sciences (DST, Govt. of India) in India with numerous laboratories continuously identifying genes which confer tolerance traits. Our laboratory at the University of Calcutta has been involved with the identification and analysis of dehydrins (drought responsive proteins) for its potential in drought tolerance. We chose Physcomitrella patens, a moss, for our molecular analysis as it would mark the evolutionary pattern from lower to higher group of organisms for the protein group under study. Physcomitrella is a well-known dehydration tolerant plant. In this study, a comparative analysis has been drawn for the three dehydrins PpDHNA, PpDHNB and PpDHNC from P. patens. Our data shows that PpDHNA and PpDHNB play a major role in cellular protection during osmotic stress. PpDHNC possesses antibacterial activity evident from NPN and SEM analysis and thus may have a role in biotic stress response. Overexpression of PpDHNA, PpDHNB and PpDHNC in transgenic tobacco depict the protective property of dehydrins. These results suggest dehydrins from moss can contribute to tolerance of drought stress and be effective against a variety of pathogens thus, finding its use in biotechnological manipulation of crop plants and development of high yielding and stress resistant crops.

Ms DEENA PRAKASHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Indira Gandhi

National Open University (IGNOU), New Delhi


Background: Medicinal plant has always been part of Indian medicinal approach. The present study is aimed to determine the phytochemical constituents, antioxidant potential and protective effect of Selaginella bryopteris (SB) extract in Acetaminophen and Carbon tetrachloride-induced hepatotoxicity in HepG2 cell line. Materials and Methods: The aqueous and ethanolic extract of S. bryopteris (whole plant)were prepared and determined the qualitative phytochemicals, total phenolic content and free radical scavenging activity using DPPH, ABTS and hydrogen peroxide (H2O2) followed by HPLC analysis of plant extracts. Hepatoprotective activity of both the SB extracts at three concentrations i.e., 25, 50, 100 ?g/mL was assessed by in vitro cytotoxicity (MTT) assay against acetaminophen and carbon tetrachloride-induced toxicity in HepG2 cell line. In vitro antioxidant potential was evaluated on the basis of DPPH, ABTS, and hydrogen peroxide scavenging abilities. Results: Qualitative and quantitative phytochemical analysis of SB extracts confirmed the presence of various phytochemicals like flavonoids, reducing sugar, anthocyanins, coumarin, steroid, alkaloid, and glycosides. HPLC analysis of plant extracts also revealed the presence of bioflavonoid like Amentoflavone. Antioxidant assays like DPPH, ABTS, and H2O2 revealed that SB extracts possessed dose (100-500?g/mL) dependent free radical scavenging activity. The maximum percent inhibition (72-88%) was found in ethanolic extract compared to the Ascorbic acid. The phenolic content was also higher (591 µg/mg) in ethanolic extract than aqueous extract (70µg/mg). In vitro studies showed the protective effect of SB in a dose-dependent manner against CCl4 and APAP induced cytotoxicity in HepG2 cell line. Conclusion: The results indicated that S. bryopteris has significant antioxidant activity and ameliorative effect against acetaminophen, and carbon tetrachloride toxicity in HepG2 cell line.

Mr SATDEV SATDEVImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bihar Agricultural university,

Sabour, Bhagalpur, Bihar 813210


Abstract: After the green revolution due to use of higher dose of inorganic fertilizer as well as intensive cultivation, imbalance nutrient status problems are creating in the soil. The imbalance of macro & micro nutrient in soil resulted in decrease of nutritional quality in the edible portion of crop due to wild spread nutritional deficiency disorders. The nanotechnology is innovative ideas in 21st century. Nano-forming fertilizers are carrier of nutrient having less than 100 nm particles size and there nutrient-ion holding capacity is higher due to its higher surface area as well as slow/controlled release of nutrient as compared with conventional fertilizers. Nano-forming fertilizers improves the nutrient use efficiency and preventing the ion either getting fixed or losses due to leaching. In agriculture involves the use of nano-fertilizers with unique properties (increased uptake by plants as they are smaller in the size and having high rate of penetration through plant cell membrane) to enhance crop productivity as well as significantly increased microbial activity. Applications of nanotechnology in agricultural science such as nano fertilizer, nano formulation pesticides and nano remediation have been used for crop production and the reduced air, water and environmental pollution and encourage the development of ecofriendly and sustainable agriculture. Keywords:- Nanofertilizer, crop productivity

Ms RIMPA SIKDERImage Delegate ID Theme Details


Research


OF CALCUTTADesignation : RESEARCH

SCHOLAR

Mother Nature is the ware house of most effective drugs and therapeutics for treating a wide range of deadly diseases. Among all cancer is the second leading cause of death around the world and hepatocellular carcinoma (HCC), the sixth most common cancer globally with highest mortality rate. Extensive research to find a palliative cure, led to develop therapeutics from natural resources, as most of the offered treatments possess acute side effects. From all the natural resources that have been explored, mushroom have come up with immense potentiality. Mushrooms and their active compounds have therapeutic properties that possess a key role in cancer treatment. A pure single compound named ‘Peroxolenteneol’ from L. squarrosulus has been isolated and chemically characterized for the first time in our laboratory. The molecular mechanism behind the apoptogenic activity of ‘Peroxolenteneol’ was evaluated on Hep3B cells by showing definitive shrinkage and deformities in nuclei, increased ROS production, positive change in mitochondrial membrane potential and release of cytochrome c with modulation of some chief apoptotic proteins like downregulated Bcl-2, upregulated Bax, p-Akt, p-pTEN, Fas-R, induced cleavage of pro-caspase 9, 3 and 8 along with PARP depicts the existence of both extrinsic and intrinsic pathway. Evidences referred that ‘Peroxolenteneol’ exhibit remarkable anticancer effect and can raise a new hope for its use in anticancer therapy in coming time.

Dr SUTAPA SANYALImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Krishnagar

Govt CollegeDesignation : Assistant

Professor

Abstract: Researches in food sciences are now concentrated on protective bacterial cultureseffective against food borne pathogens and food spoilage organisms. The aim of the present researchproposal is to lay base line information on the biopreservative potentiality of the indigenousmicroflora of fish. Bacterial strains were isolated from Oreochromis sp. and tested for potentialantagonistic activity. Samples were enriched for Lactic acid bacteria (LAB) in MRS broth and platedonto MRS agar plates. Inhibitory activity was detected by the agar spot method using Aeromonashydrophila (ATCC 646), Pseudomonas aeruginosa (ATCC 1688) and Listeria monocytogenes (ATCC 657) asthe primary indicator organisms. Twenty three LAB isolates were examined for inhibitorypotentiality. In agar spot assays of 86.95% tested isolates, inhibitory zones were found, and nogrowth circles were observed. Thus antagonistic activities may be due to synthesis of antimicrobialsbut not for the competitive exclusion. LAB strains exerted strong resistance with zones ofinhibition extending from minimum value of 10 mm to maximum of 17 mm. All the inhibitory LABstrains, except one, were antagonistic either toward one or two of the studied pathogenic strains.Inhibition was maximum for Aeromonas hydrophila (ATCC 646) and minimum for Listeria monocytogenes(ATCC 657). LAB isolates were effective in suppression of pathogenic strains either with live cellsand CFS (cell-free supernatant, neutralised and heated) or purely in the form of live cells.Synergetic effect against Aeromonas hydrophila was found when all Aeromonas inhibitors were mixedand used to test in vitro experiment. This actually opens the application of more than oneantimicrobial as a cocktail drug. Susceptibility of pathogenic and spoilage flora to LABantimicrobials seemed to be caused by thermostable compounds or other substances connected with livecells and could be applied in fisheries industry as food safety adjuncts for use asbiopreservatives.

Prof Asit RayImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Mahatma

Gandhi CollegeDesignation : Assistant

Professor

Diversity of mycorrhizal population in the popular clones and seed jats of Camellia sinensis in the selected organic and inorganic tea gardens of Darjeeling hills Asit Ray* and Aniruddha Saha Department of Botany, Mahatma Gandhi College (Sidho Kanho Birsha University), Lalpur, Daldali, Purulia, India – 723130 Molecular Plant Pathology and Fungal Biotechnology Laboratory, Department of Botany, University of North Bengal, Raja Rammohanpur, Darjeeling, India - 734013 Corresponding Author email- [email protected] Abstract: Mycorrhiza are the oldest know symbiont. Mycorrhiza are associated with improvement of nutrient deficiencies and biological protectant in agriculture. Mycorrhiza plays an important role in tea plantation as bio-fertilizer. Darjeeling tea is famous worldwide for its flavor and aroma. Popular clones of Darjeeling tea AV-2, P-312, China jats and Assam jats were taken from the selected seven organic and seven inorganic gardens of Darjeeling tea to study the mycorrhizal population. Diversity and distribution of mycorrhiza in tea rhizosphere shows important role in enhancement of uptake of nutrients from soil by roots of tea plants. Hence, present study was undertaken to estimate the population of different mycorrhiza in the organic and inorganic tea gardens of Darjeeling hills by the method of Gerdemann and Nicolson, 1963. Characterization and identification of the AMF spores where done by the INVAM catalogue. This study reveals the population of mycorrhiza in conventional (inorganic) and non-conventional (organic) Darjeeling tea plantation. In conventional (inorganic) and non-conventional (organic) tea plantations different species of Glomus sp., Gigaspora sp., Acaulospora sp., Sclerocystis sp., Scutellospora sp. etc where found. The populations of mycorrhiza were more in the non-conventional (organic) tea plantation. In respect to the Darjeeling tea clones the population of mycorrhiza show higher to lower value in China jats, P-312, AV-2 and Assam jats respectively. Both endo and ectomycorrhizal population were present in both organic and inorganic tea estate. Reference: 1. Gerdemann J.W. and Nicolson T.H. (1963) Spores of mycorrhizal endogone species extracted from soil by wet-sieving and decanting. Trans.Br. Mycol. Soc. 46: 235-244. 2. Hijri I., Sykorova Z., Oehl F., Ineichen K., Maeder P., Wiemken A. and Redecker D. (2006) Communities of arbuscular mycorrhizal fungi in arable soils are not necessarily low in diversity. Molecular Ecology. 15: 2277-2289. 3. Oehl F., Sieverding E., Mader P., Dubois D., Ineichen K., Boller T. and Wiemken A. (2004) Impact of long-term conventional and organic farming on the diversity of arbuscular mycorrhizal fungi. Oecologia. 138: 574-583.

Dr Neeraj KumarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICAR-National

Institute of Abiotic Stress Management


The climate change is worsening the problems of arsenic poisoning in aquatic water ecosystem inIndia and outside the country. Its poisoning mainly spread through groundwater and other means. Thecultivated fish are prime level of arsenic poisoning and subsequently affected on consumer andoccurrence of several diseases in animals and human. However, we designed an experiment withconsideration of above points. The experiment was carried out to delineate the effects of seleniumnanoparticles (Se-NPs) and riboflavin (RF) on alleviation of arsenic and temperature in term ofgrowth performance, anti-oxidative status and immunomodulation and thermal tolerance of in thePangasianodon hypophthalmus. Se-NPs was synthesis through fish gills using green synthesisapproaches. The four isocaloric and isonitrogenous experimental diets were prepared. The fishes werereared under arsenic (As, 1/10th of LC50 (2.6 mg/L) and high temperature (34 °C) and fed with orwithout Se-NPs and RF diet for 90 days. The eight treatments were designed in triplicate form witheighteen (18) fish were randomly distributed in each tank. The supplementation of Se-NPs and RF weresignificantly (panti-oxidative status, lipid peroxidation, stress biomarkers (acetylcholine esterase, vitamin C,blood glucose, heat shock protein 70, cortisol), immunological parameters (total protein, albumin,globulin, A:G ratio, NBT, total immunoglobulin, myeloperoxidase) and thermal efficiency in fish. Thefishes were infected with pathogenic bacteria Aeromonas hydrophila and observed cumulative mortalityand relative percentage survival for 7 days after post infection. The bioaccumulation of the arsenicwas determined in the experimental water and different fish tissues. The supplementation of Se-NPsand RF was significantly reduced the level of arsenic in fish tissues including muscle tissue.However, overall results indicated that synergistic effect of dietary Se-NPs and RF has beenperformed and alleviated multiple stresses in P. hypophthalmus.

Ms ALPANA KUSUMImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : BIHAR

AGRICULTURAL UNIVERSITY, SABOUR

Designation : Ph. D Scholar

A pot experiment was conducted during Kharif 2018 at RPCAU, Pusa with an objective to find out the effect of vermicompost prepared from household waste and cow dung (1:1, w/w) on soil properties, rice yield, nutrient uptake and nutrient use efficiency. Four levels of vermicompost 0, 1.25, 2.5 and 3.75 t ha-1 along with three levels of chemical fertilizers viz. 0, RDF (120:60:40 kg ha-1. N: P2O5: K2O) and 50% RDF in a completely randomized design. Results indicated a significant build-up of available major nutrients in post-harvest soil of rice on application of graded dose of vermicompost alone or in combination with different dose of fertilizer. Integrated application of vermicompost @ 3.75 t ha-1 and RDF recorded 25.55%, 14.79% and 41.27% increase over control in available N, P2O5 and K2O respectively in post-harvest soil. Increasing dose of vermicompost and chemical fertilizer separately and in combination significantly increased grain and straw yield as well as major nutrient uptake. Whereas, nutrient use efficiency was observed greater on combined application of vermicompost and chemical fertilizer than their alone application and treatment receiving vermicompost and 50% RDF recorded greater nutrient use efficiency in comparison to same dose of vermicompost and full dose of fertilizer (RDF). Treatment involving application of vermicompost (2.5t ha-1) along with full dose of fertilizer (RDF) gave superior results and emerged out as best treatment combination with respect to nutrient availability, growth and yield of rice crop. However, application of vermicompost (1.25 t ha-1) with 50% RDF yielded equally as full dose of chemical fertilizer (RDF) alone which indicates that 50% of chemical fertilizer could be saved on application of vermicompost even at lower dose combined with 50% RDF without reduction in grain yield. Keywords- vermicompost, rice, yield Reference: 1. Kusum, A. M.Sc. (Agri.) thesis, RPCAU, Pusa (Bihar) 2019.

Dr Jhansi R NathanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Anna University, Chennai

Designation : DST- INSPIRE Faculty

Angiogenesis, the formation of new blood vessels by sprouting from pre-existing endothelium, is asignificant component in tumor progression. Marine natural products have proved to be a rich sourceof novel compounds in drug discovery especially in the area of molecular-targeted anticancerchemotherapeutics. Marine tunicate symbiotic actinomycetes due to its unique environmental nichearise as a new and valuable source of inhibitors of angiogenesis. In the present study,actinomycetes strains were isolated from the areas of Muttom, Kanyakumari, Tamilnadu, India and itwas screened for their ability in production of bioactive compounds. The bioactive compoundsobtained were treated on zebrafish embryos at 50% epiboly stage and maintained for 72 hours postfertilization (hpf). RBC staining was done at 72hpf to study blood vessel formation in embryostreated with biomolecules and RT-PCR was carried out to study mRNA expression of vegfaa at 72hpf. Biomolecules (T1 and T2) extracted from marine actinomyetes showed anti-angiogenic property byreducing the ISVs (main angiogenic blood vessel) at 5µM concentration. RT-PCR study reveals thereduction in mRNA expression of vegfaa. Our study emphasizes the importance of potential ofanti-angiogenic compounds from marine tunicate symbiotic actinomycetes using zebrafish as in vivomodel system.

Ms YAZHINI PRABHA MImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Alagappa

UbiversityDesignation : Ph.D Scholar

Presently the progress of green chemistry in the synthesis of nanoparticles with the use of plantshas engrossed a great attention. In this study, selenium nanoparticles were biologically synthesizedusing the extract of Morinda tinctoria (Mt) fruit. The synthesized Mt-Se NPs were characterized byUV–Vis spectrophotometer, XRD, FTIR and SEM analysis. TEM analysis of Mt-ZnO NPs showed thesurface morphology. Mt-Se NPs control the growth of clinical (E. coli and P. aeruginosa) pathogens.Inverted light microscopic images revealed that Mt-Se NPs strongly inhibited the biofilm formingability of clinical bacteria. In addition, Mt-Se NPs exhibited potential antioxidant property (Freeradical scavenging activity) and low hemolytic activity. The stereomicroscopic studies of Mt-Se NPstreated Cx. quinquefasciatus larvae revealed effective larvicidal activity with determined LC50 –3.84 µg mL-1 and LC90 – 9.12 µg mL-1 values and the presence of damaged cells and tissues in themid-gut. The damaged were observed after 24 hrs of incubation. Thus the study concludes that Mt-SeNPs showed effective control of clinical bacterial biofilm which can be effective naturalnanomedicine against microbial infection and also exhibits immense larvicidal property.

Ms Ritwika ChatterjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Maulana Azad College, University of Calcutta


Tea is one of the most widely consumed beverages in the world, with a global market comprising offour major zones: Asia-Pacific, Europe, North America and Africa. The most popular means ofconsumption are in the form of black tea and green tea, whereas oolong, red or white tea are otherless popular forms. All four types are made from the same plant Camellia sinensis. This study wasconducted using pregnant rat models, to potentiate plausible effects of black tea consumption ifany, on thyroid hormone and reproductive health during pregnancy as well as the lactation period.Pregnant female (120 ± 10 g) Wister albino rats were chosen for this study. Group 1 was controlgroup where pregnant female rats were treated with saline. Group 2 and Group 3 were pregnant femalerats treated with 50 mg and 100 mg BTE/kg/day, respectively, throughout prenatal and postnatalperiods (21 days + 21 days). All three groups of rats were provided food and drinking water adlibitum. Serum T3, T4, TSH, E2 and P4 were estimated from pregnant rats of different experimentalgroups on day 0, 20 and 42. Histological studies of thyroid, ovary and uterus was done on day 42.The data generated on various parameters were subjected to statistical analysis for reporting groupmeans and standard deviation (mean±SD) with significance between the controls and the treatedgroups (n=6 in all experiments, except the biomorphometric analysis of pup where n=18). Collecteddata were subjected to one-way analysis of variance (ANOVA). BTE significantly increased serum T3,T4 level and decreased TSH level. Histology of thyroid showed BTE increased the size of thyroidfollicle and decreased colloid content. This study confirmed that BTE alter thyroid physiology inpregnant rats. Further studies are warranted to establish BTE induced changes at the molecularlevel.

Ms Shailja kumariImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Shoolini

University, SolanDesignation : Ph.D

Biotechnology student

The genus Cladosporium is one of the largest genera of dematiaceous hyphomycetes, and is characterized by a coronate scar structure, conidia in acropetal chains and Davidiella teleomorphs. More than five hundred taxa have been attributed to Cladosporium. Some species of genus Cladosporium are pertinent as possible bio-control agents for plant diseases and also in the food industry to prevent spoilage in fruits, cereals such as barley, oat, rye and wheat. Cladosporium species shows the antifungal activity against Candida albicans, P. viticola and P. obscurans. The strain of Cladosporium species was isolated from medicinal plant Ampelopteris prolifera. Cladosporium xanthochromaticum is an endophytic fungus. Endophytes are organisms, often fungi and bacteria, that live between plant cells. On the basis of morphological and molecular characterization it is proved that the isolated endophyte was C. xanthochromaticum. The present study was done to check the antagonistic property of fungi C. xanthochromaticum. The antifungal potential of C. xanthochromaticum was determined by comparison of the dry weight of the fungus against Chaetomium globosum, Aspergillus niger, Fusarium species, Rosellinia necatrix and Sclerotinia sclerotiorum. The comparative results of dry weight of the fungus from the test tubes with Cladosporium xanthochromaticum bit was greater than that of dry weight of the other fungi with Cladosporium xanthochromaticum bit and the supernatant of Chaetomium globosum, Aspergillus niger, Fusarium species, Rosellinia necatrix and Sclerotinia sclerotiorum. The above experiment concluded that the fungi Cladosporium xanthochromaticum have an antifungal potential for all targeted five fungal species. The maximum inhibition was shown against the Rosellinia necatrix and minimum inhibition against the Sclerotinia sclerotiorum. Therefore, from the present investigation it can be concluded that the isolated species C. xanthochromaticum is a good inhibitor of the plant pathogens and can act as a potential biocontrol agent.

Keywords: Anti-fungal dual culture bioassay, Cladosporium xanthochromaticum, antifungal test, MIC, biocontrol agent.

Ms swati guptaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-NBRIDesignation : PhD Scholar

Global warming has been reaching to an alarming situation and leading to change in climaticcondition up to a dangerous level. The irregular rainfalls, drought, flood and land degradation andother such factors are the major consequences of these climatic changes and causing a decrease inthe productivity of many economically important food crops. To study the effect of drought and themechanism of drought stress tolerance, a comparative proteomic analysis of roots of thehydroponically grown three week old chickpea seedling was performed at different time points afterdrought induction using 2-Dimensional gel electrophoresis (2-DE). After PD-Quest analysis 110differentially expressed spots were subjected to MALDI-TOF/TOF and among them75 spots wereidentified with a significant score. These identified proteins were classified into eight categoriesbased on their functional annotation. Proteins involved in carbon and energy metabolism comprised23% of the total identified proteins whereas proteins related to stress response represented 16% ofthe total protein spots followed by those involved in protein metabolism (13%), ROS metabolism(13%), signal transduction (9%), Secondary metabolism (5%) and N and amino acid metabolism (7%). Theabundance of some proteins was validated using western blotting and Real Time PCR. The informationfor root proteins responsible for better drought tolerance, inferred by comparative proteomicsanalysis, may further be used in genetic engineering as well as breeding programs for the benefit offarmers practicing chickpea.

Ms Neha YadavImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-NEERI,

Delhi Designation : Project

Assistant

ABSTRACT

Among all pesticides, organophosphate (OPPs) is the second largest widely used pesticide to control the pernicious organism spoiling the crop. Time and again use of these pesticides not only affected the targeted organisms but its unremitting use has started shown deleterious effect on other soil microbiota. Perseverance nature and prolonged exposure to OPPs under sub-humid tropical rice cropping system has forbid their use in many countries. OPPs rapidly degrade by hydrolysis on exposure to sunlight, air and soil into several toxic intermediates that percolates into the underground water system and elevate serious health risks associated with this class of compounds. The more pesticides used; more vulnerable the environment has become. Nature has its own remedy process and search for such biological weapons have started which could effectively remove theses persistent pesticides from soil. In this study, we searched for such bio-bugs that could degrade/eat away these OPPs and its intermediate products. The bioavailability of one such compound i.e. chloropyrifos was achieved by a native bacterium (S3-B) ‘Bacillus cereus’ isolated and identified from the soil samples of the agricultural field situated in nearby Delhi region. GC-ECD analyzer showed the presence of chloropyrifos in the soil sample. This isolate was identified as Bacillus cereus by 16S rRNA sequencing. The ability of Bacillus cereus to degrade chlorpyrifos was investigate under different concentrations of chlorpyrifos ranging from 0.5 to 100 mg/L at 30oC for 72 hrs. Focus was made to establish the pathway by identifying the intermediary products produced during the degradation process using GC-ECD analyzer. It was observe that even at this concentration (100mg/L), Bacillus cereus was able to sustain the dose efficiently.

KEYWORDS: OPPs-Chlorpyrifos, Soil, Bacteria, 16S rRNA sequencing, Degradation, GC-ECD analyzer. 1*Corresponding Author: [email protected]

Ms Anushka KhasnobishImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Okayama

UniversityDesignation : Doctoral

Student

Abstract: Berger's disease or immunoglobulin A nephropathy (IgAN) was reported to have worldwideprevalence rate range from 2% to 52% with 7-16% prevalence in Indian subcontinent. In Asia, Japanhas the second highest incidence of IgAN in the world and 20% to 50% of Japanese with IgAN developfatal end-stage kidney disease. The pathogenesis of IgAN is poorly understood, and development ofdiagnostic methods that do not rely on renal biopsy has been slow. Studies in recent years havereported relationships of diseases like ulcerative colitis, chronic kidney disease, and dysbiosiswith salivary microbiome. In this study, saliva was collected preoperatively from 43 Japanese IgANpatients and 38 age-matched healthy volunteers (HC). Total microbial DNA extracted from thesesamples was then analyzed by using 454-pyrosequencing technology. Alpha-diversity parameters(Operational Taxonomic Units, Chao1) differed significantly between IgAN and HC samples (ppaired t-test). At the phylum level, the Firmicutes/Proteobacteria ratio was lower, but theFirmicutes/Bacteroides ratio was higher, in IgAN samples than in HC samples. Within the phylumFirmicutes, Streptococcus species were more abundant in IgAN samples. These findings suggest thatsalivary microbiome composition differs in persons with IgAN. This is the first reported study ofthe mouth–kidney–microbiome axis in IgAN in the Japanese population and the findings werecomparable with prior published studies on Italian and Chinese population indicating the potentialof using salivary microbiome as biomarker for IgAN diagnosis across populations. These preliminaryresults will be used in combination with metadata to design an IgAN diagnostic model that usessalivary samples and will be useful for advancement towards early diagnosis of the Berger's diseasein the world population including Indian population.

Ms Reeta BhatiImage Delegate ID Theme Details


Research


universityDesignation : Research

Scholar

Arsenic is a toxic metalloid and considered harmful due to its toxic and carcinogenic effects. It is widely distributed in the environment due to natural geochemical processes and anthropogenic activities. At present, arsenic is estimated to affect more than 150 million people worldwide with its increasingly elevated concentration in drinking water. Thus, removal of arsenic is of great importance for human welfare. The most common oxidation states of arsenic in the environment are the pentavalent arsenate As(V) and the trivalent arsenite As(III). In this present study, a novel rod shaped gram positive bacteria was isolated from Delhi NCR. This isolate could survive in a medium containing sodium arsenate concentration up to 5000 ppm and 1500 ppm of sodium arsenite concentration. Morphological, biochemical and molecular identification was done. The optimum temperature and pH were found to be at 37? and 7, respectively. The growth pattern of the isolate in the absence and presence of arsenic was also observed. The AgNO3 test based microplate method revealed that isolate bacillus sp. have potential in transformation of sodium arsenate to sodium arsenite. The bacterial strain was resistant to recommended doses (30 mcg) of some antibiotics like Neomycin, Tetracycline, Vancomycin, Nalidixic acid, Chloramphenicol, Kanamycin, Doxycycline and was sensitive for and Amoxyclav. The arsenic extrusion from the cells results in reduced accumulation of arsenic inside the cells as confirmed by SEM-EDX analysis. Hence, this strain is useful for the development of effective bioremediation strategies in the detoxification of arsenic from polluted environments.

Dr Santosh Kumar SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Banaras

Hindu UniversityDesignation : DST-INSPIRE

Faculty

Human immunodeficiency virus type-1 (HIV-1) belongs to family Retroviridae, the etiological agent ofacquired immuno-deficiency syndrome (AIDS), is known to infect human cells bearing CD4 antigens. Theviral genome encodes three structural proteins (Gal, Pol and Env), two regulatory proteins (Tat andRev) and four accessory proteins (Nef, Vif, Vpu and Vpr) (Frankel and Young, 1998). Nef and Vpushares multiple overlapping functions like downregulation of CD4, MHC-I, protecting infected cellsfrom ADCC (antibody dependent cell mediated cytotoxicity) response in addition to their specializedfunctions. Nef promotes the localization of Gag to cell membrane for cell to cell viral transfer,enhances the incorporation of Env products to virions, enhances Tat-mediated viral transcriptionwhereas Vpu antagonizes BST-2 and helps in Env maturation. Similarly Vif and Vpr antagonizesAPOBEC3G in addition to their specialized functions like Vif enhances the infectivity and mediatesthe degradation of Vpr while Vpr targets pre-integration complex to nucleus, mediates G2 cell cyclearrest and trans-activation of cellular genes (Pham et al., 2014; Poon et al., 2007; Qi and Aiken,2008; Schiavoni et al., 2004; Vassena et al., 2015).

Dr KAMLESH KUMARIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DDU COLLEGE, DELHI

UNIVERSITYDesignation : ASSISTANT

PROFESSOR

Chikungunya virus (CHIKV) causes Chikungunya fever (CHIKF) and till date no effective medicine for its cure is available in market. Different research groups find various possible interactions between small molecules and non-structural proteins, viz. nsP3, one of the most important viral elements in CHIKV. In this work, authors have studied the interactions of nsP3 protease of CHIKV with pyranooxazoles. Initially, a one-pot three component reaction was designed using oxazolidine-2,4-dione, benzaldehyde and cyanoethylacetate to get a proposed biological active molecule i.e. based on pyranooxazoles. The mechanism for the synthesis of the product based on pyranooxazole was studied through DFT using Gaussian. Then, a library of the obtained pyranooxazole was created through computational tools by varying the substituents. Further, virtual screening of the designed library of pyranooxazoles (200 compounds) against nsP3 protease of CHIKV was performed. Herein, CMPD 104 showed strongest binding affinity towards the targeted nsP3 protease of CHIKV, based on the least binding energy obtained from docking. Based on docking results, the pharmacological, toxicity, biological score and Lipinski’s filters were studied. Further, DFT studies of top five compounds was done using Gaussian. Molecular dynamics (MD) simulation of nsP3 protease of CHIKV with and without 104 was performed using AMBER18 utilizing ff14SB force field in three steps (minimization, equilibration and production). This work is emphasized to designing of one-pot three component synthesis and to develop a theoretical model to inhibit the nsP3 protease of CHIKV. Keywords Chikungunya virus, nsP3 protease, one-pot reaction, docking, MD simulation, MM-GBSA and DFT

Ms Pubali MitraImage Delegate ID Theme Details


Research


CalcuttaDesignation : DST-INSPIRE

Senior Research Fellow

Urolithiasis or Kidney Stone Disease (KSD) is one of the most common clinical problems worldwidethat involves stone formation in human urinary system. It is a multi-factorial disease, resultingfrom combined influence of both environmental and genetic risk factors. Based on the result ofchemical and infrared spectrometric analysis, it has been found that the main constituent of kidneystone is calcium in West Bengal population. So our study was aimed to find out if there is anyassociation between genes which regulate calcium homeostasis in our body and urolithiasis.Accordingly we focused mainly on the genes which regulate calcium balance and calcium handling inhuman body. A case-control study was performed with KSD patients recruited from Department ofUrology, IPGME&R, Kolkata and age-sex-ethnicity matched healthy individuals enrolled as controls.Comparison of the clinical data revealed urolithiasis patients as hypercalciuric. For the geneticanalysis, peripheral blood sample was collected from each of the study participants followed bygenomic DNA isolation, amplification of the desired region of gene by PCR, then genotypedetermination by forward and reverse strand DNA sequencing, sequence alignment between case-controland finally statistical analysis. Detailed analysis of results revealed association of singlenucleotide polymorphisms of genes encoding calcium homeostasis mediating hormones (calcitonin andPTH), calcium sensing receptor (CaSR) and calcium channel protein (TRPV5) with urolithiasis. SNPsrs1801197 of CALCR, rs307247 and rs307248 of PTH, rs1801725 and rs1042636 of CaSR and rs4236480 ofTRPV5 were found to be significantly associated (p-value West Bengal, but no association was found for VDR (Vitamin D receptor) gene. Based on the finding,it can be suggested that the above mentioned six SNPs can be used as potential genetic markers forearly detection of urolithiasis and also for preventing its occurrence in the Indian population.

Mr ALFRED BESRAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : VISVA-

BHARATIDesignation : Research

scholar

Differential effect of plant growth regulators on callus induction in common bean (Phaseolus vulgaris L) under optimum growth conditions Alfred Besra and Jolly Basak* Department of Biotechnology, Visva-Bharati, Santiniketan 731235, WB, India [email protected], [email protected]

Abstract Callus plays a vital role in plant tissue culture experiments, it can be used for micro-propagation or to create transgenic lines. Common bean (Phaseolus vulgaris L) is one of the important legume crop having a high nutritional content. India ranked 4th largest in green bean production. However very less work is done to increase the tolerances in P. vulgaris from different type of stress. Action can be taken by using callus developed from explants taken from P.vulgaris to create new tolerance line. The present study will help us to understand the optimal growth condition and plant growth regulator concentrations needed to developed a callus from P. vulgaris. Six explants were taken plumule, radicle, root tip, embryo, cotyledon and leaf. The minimum days for callus induction was found 10 days, and maximum of 15 days in Murashige and Skoog (MS medium). PGRs with BAP (1.50mg/L), 2, 4-D (0.50mg/L) and NAA (0.10mg/L) showed the best result for callus induction. Higher concentration of BAP (2.00mg/L), along with 2, 4-D (0.25mg/L) was ideal for shoot and root induction. This study reveals that out of six explants radicle and plumule was found to best explant for callus induction followed by shoot and root induction.

Dr Biplab BhowmickImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Scottish

Church CollegeDesignation : Assistant

Professor of Botany

Genome visualization by chromosome analysis set the foundation to enter genome sequencing era.Up-gradation in chromosome preparation technique is vital to establish a database for geneticresources of major crop species. India and specially Himalayan India is a repository of well knownand also many less cultivated capsicums. Discovery of highest pungent capsicum and the cultivatedpolyploid capsicum enriches the repository of our country. In the field of capsicum science we havegathered knowledge in morphology, metabolites, molecular biology and even genome sequencing.Cytotaxonomic analysis of Indian capsicum cultivars and species requires a chromosomal databasewhich has not received enough attention. Chromosomes database is the quickest, cheapest and easiestway to get substantial information about the genome. Accepting the limitations of conventionalsquash preparations we have standardized a new age method to characterize the cytogenetic attributesin many valuable diploid and polyploid germplasms under three Indian capsicum species for the firsttime. The advanced method is known as enzymatic maceration and air drying (EMA) followed by Giemsastaining to ensure cytoplasm free preparations, well scattered metaphase chromosomes with clearmorphology. The method allows reusing slides to perform fluorescence banding with stains for AT andGC rich repeats on metaphase chromosomes. Our results on three cultivated species viz. C. annuum, C.frutescens and C. chinense revealed distinct differences in karyotypes in spite of similar ploidyand overlapping morphological traits. Polyploid status of taxonomically unresolved ‘DaleKhursani’ cultivar and unique karyotype of the hottest chilli ‘Bhoot jolokia’ were the bestfit to represent genetic diversity of capsicums. We have used karyotype asymmetry indices tostatistically evaluate karyotype relations among these species. We have proved the efficacy ofadvanced chromosome preparation method to complement structural genomics. Our results will elaborateall parameters and justify the necessity of preparing chromosomal database in important crops.

Mr prabhakar babeleImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DRDO


Clostridium perfringens is an important clostridial pathogen and causative agent of several diseasesin humans and animals including gas gangrene, food poisoning and necrotizing enterocolitis. Itcauses diseases owing to its ability to produce a myriad of extracellular toxins. Epsilon toxin(ETX) is the major virulence determinant of Clostridium perfringens and is one of the most potenttoxin known. It is considered to be a potential biothreat agent and grouped in the category B ofbiological agents by Centre for Disease Control and Prevention. For the aforementioned reasons andin the prevailing scenario of bioterrorism; the rapid toxicity of ETX warrants early diagnosis forimplementation of therapeutic medical countermeasures. Classical sero-diagnostic tools likeimmunoassay are not effective for early diagnosis due to low lethal dose and rapid binding of ETX toits target receptors. Host protein marker signatures in serum can be the plausible answer for earlydiagnosis of ETX exposure. The present study describes gel-based and gel-free mass spectrometrybased approach to elucidate the common post-translational modifications (PTMs) and differentialproteins in host as marker signatures following intravenous injection of toxin in mouse model. Intotal, 24 proteins were found to be post-translationally modified on 122 peptides and 353 siteswhereas 119 proteins were significantly up-regulated and 47 proteins down-regulated. Alpha-2 HSglycoprotein, alpha anti-trypsin, serotransferrin and alpha globin are important proteins thatshowed differential phosphorylation and glycosylation events. Differential quantification datahighlighted apolipoprotein AII, glutathione peroxidase, serum amyloid A and vitamin-D bindingprotein as putative marker for ETX exposure. Pathway analysis indicated perturbations in bloodcoagulation, lipid transport and oxidative stress. To the best of our knowledge this study providesthe first differential PTMs profile of host response in serum against intravenous ETX exposure, thusproviding clues to mechanism of toxicity and potential diagnostic tools.

Dr Avinaba MukherjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Charuchandra


Professor

Induction of Apoptosis in Lung Cancer Cells by Quercetin through Stress Modulation via DNA interaction Avinaba Mukherjee* [email protected] Assistant Professor Department of Zoology, Charuchandra College

Abstract: Quercetin, an well known flavonoid is being found in many vegetables in plenty of amount (1). Its role as an anticancer agent has long been investigated1. However, lung cancer in kras mutated state shows very high percentage of survivility against any chemopreventive drugs (2). Therefore, the present study has been made to investigate whether quercetin has any apoptotic activity against kras mutated lung cancer cells or not. A549 and H460 lung cancer cell lines having kras mutation has been taken and quercetin was induced into them. Experimental observation reveals that quercetin at a very minimum dose exerted apoptotic activity particularly on A549 cells. Significant amount of subG1 stage arrest and annexinV positive cell populations was found after quercetin induction. After quercetin induction reactive oxygen species (ROS) level was not found to be modulated and the antioxidant level was not found to be depleted. Therefore, the apoptotic activity was found to be occur in a ROS independent manner and also not even through antioxidant depletion. Thereafter drug-DNA interaction was investigated through circular dichroism assay. Spectral analysis have showed that quercetin at very early hour significantly interact with DNA and this might increases the stress which in the later part was supposed to be responsible for apoptosis in lung cancer cells.

References: 1. Anand David A.; Arulmoli R.; Parasuraman S. Pharmacogn Rev. 2016, 10, 84-89. Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid.Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. 2. Del Re, M.; Rofi, E.; Restante, G.; Crucitta, S.; Arrigoni, E.; Fogli, S.; Di Maio, M.; Petrini, I.; Danesi, R. Oncotarget. 2017, 9, 6630-6643. KRAS mutations in acquired resistance to treatment in NSCLC.

Mr Gourab SahaImage Delegate ID Theme Details


Research


Statistical InstituteDesignation : Ph.D Scholar

Pancreatic Ductal Adenocarcinoma (PDAC) is cancer of exocrine pancreas having 5-year survival rates remaining constant at 7% and going to become the second most common cause of cancer-related deaths by year 2030. Along with PDAC, Periampullary Adenocarcinoma (PAC) have three other anatomical and two histological subtype accounts 0.5-2% of all gastrointestinal malignancies. Till now there are no reports of genomic architecture for these cancer from Indian patients. In this study in the discovery set we performed targeted Next Generation Sequencing in 8 (5 PDAC and 3 PAC) tumour normal pairs, using a panel of 412 cancer related genes. Subsequently the in the validation cohort “selected regions” were sequenced by Sanger sequencing in another 85 tumour samples (31 PDAC and 54 PAC). Among the total 114 detected somatic mutations TP53 gene was the most frequently mutated (41%) gene, followed by KRAS, SMAD4, CTNNB1, and ERBB3. We identified a novel hotspot TP53 mutation locus with likely driver role (p.A138V, 17% of all patients are mutants, n=16). Molecular Dynamic (MD) simulation and DNA-protein docking analysis predicted p.A138V is a novel cancer hotspot mutant to have similar oncogenic characteristics also confirmed by TMA spot (IHC) analysis, as other known TP53 cancer hotspot gain of function (GOF) mutants. Interestingly, this mutation was mostly enriched in PDAC and pancreatobiliary subtype of PAC tumours. Patients with p.A138V mutation showed poorer overall survival (p=0.01). Our finding highlights a substantially elevated prevalence of the TP53 p.A138V somatic mutation in PDAC and pancreatobiliary PAC patients. Detection of these variant might serve as a poor prognosis marker to identify patients for rapid and more aggressive forms of treatment. In future understanding on this variant associated finer clinical phenotype and it’s functional significance would have significant potential to impact in PDAC and PAC patients’ treatment and outcome.

Dr Avinash SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : IIT Mandi

Designation : National Post Doc Fellow

Sepsis is a primary cause of morbidity and mortality in critical illness throughout the world. Diagnosis of bacterial sepsis is made by culture-based pathogen detection, physiological criteria, including changes in the body temperature and heart/respiration rates. C-reactive protein (CRP) and pro-calcitonin (PCT) are currently the most commonly used biomarkers for sepsis in clinical practice. Novel sepsis biomarkers for early diagnosis is urgently required. Recently, free circulating nucleic acids in plasma /serum have been studied as biomarkers. Free circulating DNA (cf-DNA) is released from a number of cells (including neutrophils, eosinophils and macrophages) as a result of either necrosis or other forms of cellular damage cf-DNA has shown to have prognostic relevance in many conditions(trauma , stroke , cancer, diabetes mellitus, sickle cell disease, organ transplantation, and critical illness. Therefore, we aimed to explore the role of cfDNA as a potential biomarker for the early diagnosis of sepsis. Total 60 samples were taken. Of 60, 35 were from sepsis patients, 8 were other than sepsis and 17 were control samples. Patient’s laboratory and demographic data recorded from the hospital information system for further analysis. Patient demographic data showed; 25, 6 and 10 patients were male among sepsis other than sepsis and control group respectively. Mean age was 43.7 in sepsis, 45 in other than sepsis and 27.25 in control group. Procalcitonin (PCT) marker was higher in sepsis patients compare to other than sepsis and control group. Similarly, higher level of IL 6 was observed among sepsis patents compare to others. Quantification of cell free DNA showed higher level of cell free DNA among sepsis patients compares to control group. In conclusion, cell free DNA might be used as a potential biomarker for the early detection of sepsis.

Mr Asim Azhar SiddiquiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR - Indian Institute of Chemical Biology

Designation : Project Assistant Level III

Malaria is still one of the leading causes of death due to infectious diseases at the global level.The food vacuole of Plasmodium is an endo-lysosomal like structure, unique to the parasite andconsidered as its metabolic headquarters during its blood stages which are responsible for itsclinical manifestations. We detected the assembly of retromer complex of P. falciparum bycoimmunoprecipitation coupled to surface plasmon resonance and found it to be in the vicinity of thefood vacuole along with its regulator Rab7. The assembly of retromer was further used as anindicator of the functioning of food vacuole where two important pathways of hemoglobin degradationand heme detoxification by hemozoin formation take place. Inhibition of any of these pathways maycompromise the food vacuole and inhibit parasite growth. We chose the immutable target heme todevelop novel antimalarials. Heme is an iron-containing molecule; thus, we designed and synthesizedsome iron-chelating benzothiazole hydrazones that were able to interact with heme. We identified anovel compound that showed antimalarial activity. Because of its heme-binding property, weinvestigated its effects on food vacuole function because an enormous amount of heme is presentthere. We checked the retromer complex assembly and found that the lead compound caused itsdisruption similar to a known food vacuole targeting molecule, chloroquine. To further validate itsmechanism of action, we performed hemozoin formation assay in the presence of the lead compound andfound that it was able to inhibit hemozoin formation both in parasite culture and cell-free system.This compound also exhibited efficacy against the chloroquine-resistant parasite and in vivo rodentmodel of malaria with minimal toxicity. Therefore, we described the retromer assembly in P.falciparum and identified a novel chemotype that showed antimalarial activity by inhibiting hemozoinformation in the food vacuole of the parasite.

Dr Jeya Venkatesh JaigopalImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Kokila Siddha Hospital and Research Centre

Designation : Siddha Physician

XRF study on selective plant powders and their ash extracts used in Siddha Medicine Jeya Venkatesh J*, Savariraj Sahayam C** , Maniraj Kumar P*** , Saravana pandian P**** *Dr J Jeya Venkatesh BSMS, MD, PhD**** Dr P Saravanapandian BSMSKokila Siddha Hospital and Research Centre,Kunnanampattti Village, Thirumangalam Taluk,Madurai 625706**Dr.C.Savariraj Sahayam. BSMS, M.D, PhDAssistant Professor (Siddha Medicine)Centre for Advanced Research in Indian Systems of Medicine (CARISM)Thanjavur 613 401***Dr.P. Maniraj Kumar ME, PhDProfessor/ECE,PSNA College of Engineering and Technology,Dindigul 624622Corresponding Author: [email protected]:Ash extraction is a custom-made process in Siddha medicine used to collect the corrosive water soluble salts present in the burnt plant ash. It is called as satthu (extract), uppu (salt) kaaram (alkaline matter) in Siddha literatures. Generally it contains lot of elements and highly alkaline. Objectives: The main objective of the study was to compare the elements present in the two different samples of powder and ash extract prepared from aerial parts of selective plants.Materials and Methods:The two different types of dry powders obtained from crude aerial parts are subjected for the study. The powders were prepared as per classical Siddha text references. X-ray Fluorescence study for the presence of elements in solid samples using a XRF (Bruker S8 Tiger) spectrometer reveals the presence of active principles according to Siddha drug preparation techniques.Results:The results were analyzed and interpreted to explore the significance of ancient Siddha drug preparation techniques using modern parameters. Conclusion:It showed different elemental values in qualitative and quantitative drug preparatory methods based on taste and used parts. The study along with FTIR and UV Spectroscopy would explore more information regarding the ancient drug preparatory methods and the pharmacology.References:1.Shanmugavelu M Noi Naadal Noi Mudal Naadal Thirattu Part1 2003, 23.

Dr BUSHRA IQBALImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : KING GEORGES MEDICAL

UNIVERSITYDesignation : Research

Associate

INTRODUCTION:Curcumin (diferuloylmethane), the main active polyphenol derived from the rhizomes of turmeric (Curcuma longa) inhibits cell proliferation, inflammation and induces cell cycle arrest and apoptosis in variety of cancers. Importantly, Curcumin exerts its cytotoxic effect in a number of ways, including cell cycle arrest, Caspase activation and transcriptional factors activation. Curcumin reduces cell proliferation and increases the cell death in various hematological malignancies. Tumor necrosis factor (TNF)-?-related apoptosis-inducing ligand (TRAIL), is a cytokine of the TNF family which is capable of inducing apoptotic cell death in a variety of cancer cell types without harming normal cells

OBJECTIVE: To present an appraisal on potential usage of Curcumin and TRAIL in the prevention of cancer. Furthermore, it contributes an information for the use of curcumin as a chemopreventive agent against various cancers. Curcumin has a potent cytotoxic effects in vitro, especially in combination with TRAIL can be used for treatment and /or prevention of hematological diseases including CML.

DISCUSSION: The fusion of curcumin and TRAIL showed significant level cytotoxicity in cancer cells, which presents general resistance to numerous chemotherapeutic medicines.Thus, present study may provide a glimpse in darker sky of hematological malignancies and may open new ideas for therapeutic use of naturally occurring dietary products in treatment and prevention of cancer patients.

Key Words: Cancer, TRAIL, Therapeutic agent

Ms MANASWINI DASHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NRRI,Cuttack


TITLE- Generation of mutant rice plants through CRISPR/Cas9 to decipher the role of PEPC and PPDK genes Manaswini Dash, Alaka Swain, Deeptirekha Behera, Kutubuddin Ali Molla and M.J.Baig Email- [email protected] National rice Research institute, Cuttack, Odisha ABSTRACT The CRISPR (Clustered Regularly Interspaced Palindromic Repeats) associated Cas (CRISPR associated nuclease) system have been successfully used as efficient tool for genome editing in a variety of species. Cas 9 is a nuclease that uses small RNA (guide RNA) as a guide to recognize and cleave specific DNA that are complementary to the RNA. The widely cultivated C3 plant rice is not only an important food crop but also a model crop plant because of its relatively small genome and relative ease of transformation. C4 plants are more efficient in terms of photosynthesis as compared to C3 rice by reducing photorespiration. PEPC and PPDK are the major photosynthetic genes involved in the C4 pathway. Although these genes are present in C3 rice crops, their functions and regulations are not understood properly. Thus, in our experiment we have targeted editing of PPDK and PEPC genes by using CRISPR/ Cas9 system. We have designed two guide RNAs for disrupting the PEPC and PPDK genes. For enhancing editing efficiency, we fused a tRNA upstream of each guide RNA. We assembled the tRNA-guideRNAs for the two targets through golden gate assembly reaction. Assembled product was amplified by PCR and ligated to pGEMT-easy vector. Clone was confirmed through digestion by restriction enzyme. The cloned product will be further sub cloned in pRGEB binary vector and will be transformed to rice to observe the genotypic and phenotypic variation. This approach would help us better understand the roles of those genes in rice.

Mr JON JYOTI SAHARIAHImage Delegate ID Theme Details


Research


Pharmaceutical Sciences, Dibrugarh University

Designation : M.Pharm Student

Diabetes Mellitus is a disorder related with complex metabolism of Carbohydrate, Fat and proteinwhich develops the Insulin resistance into our body, ?-cell dysfunction, increased in oxidativestress and impaired insulin signalling. Consistently high levels of glucose in the blood streamdamage the nerves and blood vessels, and can lead to heart disease, stroke, high blood pressure,blindness, kidney disease, amputations, and dental disease. There are several drugs which are beingdeveloped and are being used for the control of diabetes including oral hypoglycaemic agents butthey inadequately prevents atherothrombosis and microvascular complications affecting retina,kidney, lens etc. On the other hand appropriate diets, regular exercise, and weight control canpotentially prevent the diabetes mellitus. Several types of medicinal plants are being used ashypoglycaemic in the traditional Indian medicinal system which includes Ayurveda. The nutraceuticalsare the food supplements having nutritional as well as have significant clinical and pharmacologicalactivity. Several studies show that the using nutraceuticals can control Diabetes. The mainadvantage of using these nutraceuticals is that they are having very negligible side effects relatedto the other synthetic antidiabetic drugs. Several nutraceutical agents using in clinical practicehave been shown that targets the cause of diabetes mellitus, metabolic syndroms and theircomplications and interestingly they modulates a number of chemical and biochemical endpoints. Whichincludes, antioxidants, vitamin C, E, D, Dietary fibres, phytoestrogens etc. There are severalplants which are being used and give potential antidiabetic activity. These nutrients exhibitsignificant pharmacological & clinical activity. The demand is increasing day by day by the patientsfor use of such natural products with pharmacological activity. The nutraceuticals in clinicalpractice is emerging, but the important pharmaceutical and clinical issues need to be verified byfurther researches and should be concerned about safety and toxicity issues.

Ms Priyanka GangwarImage Delegate ID Theme Details


Research


University Uttar Pradesh, Lucknow


Chickpea is the third most important legume crop grown worldwide. Specialized germplasm subgroups ofchickpea germplasm have been developed in recent years. It is speculated that germplasm diversity ofcrops contributes to improved cultivation, facilitates identification of specific traits ofgermplasm, mapping of traits and allele mining for resistance to biotic and abiotic stress toenhance crop productivity. In the present investigation, a comprehensive collection comprising 62germplasm accessions including traditional cultivars, breeding material, local varieties, andadvanced varieties was analyzed using EST-SSR markers. The SSR analysis revealed the presence of atotal of 42 distinct alleles with an average polymorphic information content value of 0.47. Amoderate level of gene diversity was ranged from 0.09 to 0.77 with an average of 0.53. Remarkably,two distinct subpopulations were recovered using the cluster as well as population structureanalysis. In addition, the presence of admixtures in the population reflects the strong likelihoodof gene flow between accessions across the worldwide geographical boundary. In the present study, weprovide additional insights on the information of EST-SSR markers available along with a distinctunderstanding of the relationship, genetic structure, and gene flow in legume crops. The molecularcharacterization of germplasm accessions in this study will positively helpful and enhance their usein various crop improvement breeding programs. Exploring new germplasm accessions for geneticvariability analysis will further helpful for agriculture to finding tolerant genes against variousbiotic and abiotic factors.

Mr Kunal DuttaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Vidyasagar

UniversityDesignation : CSIR-SRF

Since, last two decades, waste effluents and recalcitrant compounds have become an importantenvironmental concern. Among the diverse types of contaminants, polycyclic aromatic hydrocarbons(PAHs) have been given top priority by the US-EPA. Naphthalene, the simplest form of PAH isconsidered as a model compound for biodegradation studies. In last few years, different approacheshave been undertaken to improve bioutilization of polycyclic aromatic hydrocarbon by soil bacteriaviz., supplementation of secondary carbon sources (SCS), bacteria-bacteria consortium development,and cell immobilization, etc. Sucrose (0.5 wt%) has been found as a superior SCS for naphthalenebiodegradation. Moreover, the microscopic studies and flow cytometric analyses suggest that duringnaphthalene biodegradation bacterial cells change their size and shape from rod to small sphere. Thedynamic light scattering and cell surface potential are also in agreement with the microscopicstudies. The observed cell sizes were 1005, 1052, 898 and 989 nm with different species of SCS,i.e., L-arginine, sucrose, glucose, and starch, respectively. Furthermore, naphthalenebiodegradation performance by immobilized Pseudomonas sp. consortium was found superior to thesessile form of individual strain. The morphological changes in bacterial cells provide a clue forthe future direction of research on bacterial adaptation strategies in a nutrient-limitingcondition.

Dr Satyendra Pratap SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : National

Botanical Research InstituteDesignation : Research

Scholar

Chemotaxonomic profiling of Centella asiatica (L.) Urb. Collected from four phytogeographical regions of India Authors: Satyendra Pratap Singh, Sharad Srivastava Pharmacognosy & Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow-226001, India Email: [email protected]

Centella asiatica is a tropical herb, distributed in Southeast Asia, very important due to the synthesis of several therapeutically essential bioactive metabolites. The present investigation attempts to identify the elite chemotypes of Centella asiatica collected from four eco-geographical regions of India on the basis of their botanical and chemical profiling so that the same can be further cultivated to ensure quality supply of raw materials for the herbal drug industry. Total 159 accessions of C. asiatica were sampled from four eco-geographical regions of India namely Western and Eastern Himalayan Regions, Gangatic Plain, and Deccan Region for the HPTLC based quantification of four different bioactive metabolites viz., Asiaticosides, Madeccasocides, Madecassic acid and Asiatic acid. Out of four eco-geographical regions the water extractive value was found maximum in Western Himalayan and Deccan Region and 1.26 fold higher than Gangatic Plain region (Lowest). The alcohol extractive value was higher (1.1 fold) in Western Himalayan region as compare to Eastern Himalayan Region (Lowest). Moreover, phytochemical constituents i.e., Total Phenolic, Sugar, Starch, and Total Tanin Content was observed 1.95, 1.52, 1.26 and 1.72 fold higher in Deccan Region respectively as compare to Eastern Himalayan Region (Lowest). Whereas, Flavonoid content was found maximum (3.16 fold) in Western Himalayan region and lowest was revealed in Eastern Himalayan Region. Similarly, four major phyto-constituents Asiaticosides, Madeccasocides, Madecassic acid and Asiatic acid was 6.6, 3.4, 4.2, 4.1 fold higher in Western Himalayan region in contrast to Gangatic Plain (Lowest). The results of present study are of industrial importance in selection of phyto-geographical regions of India for collection and to get maximum contents of active targeted phytochemicals.

Dr Smriti RastogiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : King George's

Medical UniversityDesignation : Ph.D student

*1Dr. Smriti Rastogi, 2 Dr. Narsingh Verma 1 Ph.D Scholar, 2 Professor, Dept. of Physiology, King George’s Medical University, Lucknow *Contact address: Department of Physiology, KGMU, Shahmina Road, Chowk, Lucknow-226003 [email protected] Method 100 hypertensive diabetics enrolled from OPD, Endocrinology, KGMU, were randomly divided based on whether they have consented to the intake of Curcuma longa (Self Nano Emulsifying Curcumin SNEC 30) capsules (SNEC 30 Group) or not (Control Group). SNEC 30 contains highly bio-available 30 mg curcumin which uses SNEDDS (Self Nano Emulsifying Drug Delivery System). Patients were administered SNEC 30 thrice daily for a year. Baseline parameters of height, weight, BMI, Fasting & Post- prandial blood sugar, HbA1c, Systolic and diastolic blood pressure and lipid profile were noted. Follow up was done after an year. Standard treatment of diabetes was provided to the 50 patients of each group. Result Significant reduction was observed in fasting, post prandial blood sugar, HbA1c, systolic, diastolic blood pressure and the overall lipid profile of the hypertensive diabetic also improved significantly. For fasting and post prandial blood sugar the p values were 0.05 and 0.023 respectively. The HbA1c decreased from 8.7 to 7.1 which was significant (p value = 0.03). The systolic blood pressure showed a significant decrease (-11.9mm Hg) p value Conclusion Curcuma longa showed significant changes in parameters and can be successfully used as an adjunct in hypertensive diabetics. References: 1.Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials Subash, Patchva,1 Bharat B. Aggarwal1,2 The AAPS Journal (# 2012) DOI: 10.1208/s12248-012-9432-8 2. Curcumin Extract for Prevention of Type 2 Diabetes SOMLAK CHUENGSAMARN et al . Diabetes Care 35:2121–2127, 2012

Dr Satyendra Pratap SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Mewar University, Chittorgarh,

Gangarar, 312901 Rajasthan Designation : Ph.D. Scholar

Bacterial Endophytes mediated Elicitation of withanolide biosynthetic pathway in W. somnifera during pathogenicity of A. alternata Satyendra Pratap Singh#1, Neha Wal#, Rajeev Gaur# #Mewar University, Chittorgarh, Gangarar, 312901 Rajasthan 1CSIR-National Botanical Research Institute, Lucknow, 226001 U.P. Email: [email protected]

Endophytes are obtaining a great attention all over the globe because their potentiality in plant growth development, and defence. However, very few studies are focussed on their role in biosynthesis of secondary metabolites in host plant. The current investigation, aimed to assess the impact of bacterial endophytes on Withania somnifera plant during Alternaria alternata infection. Out of 131 bacteria, the two most potent bacterial endophytes namely Bacillus amyloliquefaciens (MPE20) and Pseudomonas fluorescens (MPE115) were selected on the basis of plant growth promoting and mycolytic activity. The individual as well as combinational mode applications of two most potent bacterial endophytes were efficiently able to ameliorate the withanolide biosynthetic pathway and suppress the pathogenicity of A. alternata in W. somnifera. The expression levels of withanolide biosynthetic pathway intermediate genes were significantly elevated in microbial consortium treated plants under A. alternata stress. Furthermore, the consortium mode application of bacterial endophytes not only enhance the biosynthesis of withanolide A, withaferin A and withanolide B (3.32-5.96 , 1.52-1.96 and 12.49-21.47 fold respectively) but also provide the resistance to host via progression of their photochemical efficiency, standardizing the non-oxized and oxidized fractions, elevation of electron transport rate and photochemical and non-photochemical quantum yield under A. alternata infection. Moreover, diminution in passively dissipated energy of PSI and PSII in combinational mode treated plants were further validates the above findings. Altogether, the study provides novel insights into the application of endophytes and their ability to accelerate withanolide biosynthesis in W. somnifera under biotic stress caused by A. alternata.

Keywords: Endophytes; Bacillus amyloliquefaciens; Pseudomonas fluorescens; Withania somnifera; Withanolides

Ms PAYEL PAULImage Delegate ID Theme Details


Research


OF NORTH BENGALDesignation : RESEARCH

SCHOLAR

Polygonaceae is a dicot family including 48 accepted genera and 1,200 known species with variegatedarchitectures. Members of Indian Polygonaceae are mainly distributed in various altitidunial rangesof Himalayan and sub-Himalayan terai, duars and plains. The family has been dichotomized into twosubfamilies viz., Polygonoideae and Eriogonoideae based on existence of ochrea. Presence of ochrea,monopodial branching and lack of involucres determines the main characteristic features ofPolygonoideae. Rationale, this study deals with the diversified floral morphology withinPolygonaceae, due to which the classification of Polygonum sensu lato has remained in the mist. Thepresent study extended the knowledge of some previous researchers by sequencing chloroplast regionof several members of Indian Polygonoideae (viz., 6 sequence of rbcL, 17 sequences of trnL-F and 10sequences of matK from 19 species of Polygonoideae) that were not sequenced earlier. Based on thesesequences of three chloroplast DNA region, phylogeny of the eight genera of Himalayan Polygonumsensu lato were re-evaluated. The results of our study came up with the following inferences like-(a) Persicaria and Polygonum sensu stricto should not be unified. Their apparent resemblance canonly be linked by their more distant affinities within the subfamily Polygonoideae and (b) Themembers of subfamily Polygonoideae have polyphyletic origin. Conclusively, based on the presentanalyses some taxonomic repositioning has also been suggested that might be helpful in unravelingscepticism in nomenclature of Persicaria and Polygonum sensu stricto.

Mr SUBHADEEP DASImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jadavpur


Research Fellow

Opportunistic human fungal pathogen C. albicans displays a morphological transition from yeast to hyphal state, which has been postulated to mimic its transition from avirulent to pathogenic form upon infection to the host tissue. Strikingly, the budding yeast Saccharomyces cerevisiae also exhibits similar transition from yeast to filamentous hyphal state upon growth under nutrient limiting conditions, thus serving as an excellent model system to study the genetics and molecular biology of pathogenic transition. However, the mechanism of formation of these pseudohyphal filaments and the regulatory signal transduction pathways by which these signaling systems are integrated is poorly understood. The protein kinase Sks1p was implicated in the integration of signals for nitrogen and/or glucose limitation, resulting in pseudohyphal growth in both S. cerevisiae Candida albicans. Thus, Sks1p constitutes a mechanism that integrates glucose-responsive cell signaling and pseudohyphal growth, whose function is required for the virulence in C. albicans. However, the regulation of the expression of the SKS1 gene is completely unknown. Recent findings in our laboratory through confocal microscopy and mRNA decay analysis indicated that SKS1 is regulated at the post-transcriptional level via a combination of mRNA export and degradation. Data of the experiments substantiating our hypothesis will be presented.

Ms JHILAM MAJUMDERImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : JADAVPUR

UNIVERSITYDesignation : JUNIOR RESEARCH FELLOW

The rewards of using microbes over other biological methods for nanoparticle synthesis have fascinated researchers to investigate mechanisms of metal ions uptake and bio-reduction by microorganisms. Here, green chemistry were employed for the synthesis of silver nanoparticles (AgNPs) using bacterial extracts of Glucanoacetobacter kombuchae (RG3) and yeast extracts of Cryptococcus laurentii(Y24). The size, shape, morphology, and stability of resultant AgNPs were investigated by optical spectroscopy, Fourier transform infrared analysis, X-ray diffraction (XRD) analysis and transmission electron microscopy (TEM). The enhanced antibacterial activity of AgNPs against a variety of Gram positive and Gram negative bacterial strains was analyzed based on the zone of inhibition and minimal inhibitory concentration (MIC) indices. Cytotoxic evaluations were made against particular cell lines by MTT assay. The characteristics of the synthesized silver nanoparticles suggest their application as a potential antimicrobial, anti-oxidant and anticancer agent. Further,AgNPs potentially attracts for the up-scaling of metallic nano materials to explore various catalytic as well as biomedical applications.

Dr Abhinav VermaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : HIMSDesignation : MBBS

out in the gymnasium Abhinav Verma1*, Narsingh Verma2, Vandana Awasthi 3 [email protected] Aim: To assess the effect of frequent consumption of energy drinks on blood pressure, heart rate and blood glucose in healthy adults working out in the gymnasium.

Methods: 200 healthy young adults, were divided into two groups: the first consumed at least three energy drinks at one-hour intervals, and the second drank the same amount of water. Systolic blood pressure (SBP), diastolic blood pressure(DBP) ,heart rate (HR) and blood glucose (BG) were measured before consumption of energy drink (250 ml per can)/ water (250 ml ) and before working out. After working out for 45 minutes (treadmill, cycling and elliptical cross trainer) 1 hr of rest was given to both groups. SBP, DBP, HR and blood glucose were then measured. All participants could report any health problems before and after consuming each portion of energy drink. All parameters were measured thrice weekly for 3 months. Results: Having consumed three portions of ED ( 150 to 180 mg of caffeine), the participants presented a significant increase in DBP (p = 0.033), by over 10.32%, no significant change in SBP (p = 0.715). HR increased in adults drinking 3 energy drinks (p = 0.040). Consumption of EDs caused a significant increase (p Conclusion: Increased diastolic blood pressure, blood glucose, no significant change in systolic blood pressure occurred in healthy young people as compared to their controls drinking water.

1.Alsunni AA. Energy Drink Consumption: Beneficial and Adverse Health Effects. Int J Health Sci (Qassim). 2015;9(4):468–474.

Mr NEERAJ KUMARImage Delegate ID Theme Details


Research


DelhiDesignation : Research

Associate

Chamki fever (also known as Acute Encephalitis) has emerged as a major health concern in India onlarge scale. Acute Encephalitis syndrome is characterized by acute onset fever leading to the braininflammations, disorientation, mental disease, coma, and other neurological disorders. Even globallycases are growing which has emerged the concern to develop the potential vaccine against this viralinfection1. In the present work, we have designed and optimized the potential multi-epitope subunitvaccine against envelope protein of Acute Encephalitis. We have employed the advancedimmunoinformatics techniques to design the Cytotoxic T lymphocyte (CTL) epitopes and validated withvarious parameters including the high antigenicity and high immunogenicity. Molecular docking andmolecular dynamics simulation have been performed to assess the molecular interaction of designedvaccine2. In results, we obtained the putative CTL epitopes (MHC restricted class-1) with highantigenicity and high immunogenicity. Multi-epitope subunit vaccine was formed by adjoining theknown linkers AAY, GPGPG and Toxin B subunit of Vibrio cholerae (CTB) adjuvant. The designed vaccinewas found to bind strongly with MHC-1 receptor, and host cell target toll-like receptor-2 (TLR2)with high docking scores; and also found to possess the optimal homing properties with hightransported associated protein (TAP) affinity score. In addition, vaccine was studied for peptidedynamics using the CABS molecular dynamics simulation module; which confirmed the stable andspecific binding of vaccine to the target receptors with lower RMSD value. This study gives thepotential multi-epitope subunit vaccine for Indian Chamki fever; which can be further evaluatedthrough in vitro and in vivo cell studies.

Mr Bibhas BhuniaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Indian Institute of Technology

GuwahatiDesignation : PhD Scholar

Disc degeneration is the major cause of low back pain (LBP) damaging the intervertebral disc (IVD),a soft cartilaginous tissue that holds the vertebrae together [1]. Recapitulation of annulusfibrosus (AF) tissue (the outer multilamellar ring-like structure of IVDs) intricacy is one of thechallenging tasks to the tissue engineers using conventional fabrication techniques. 3D printingtechnology provides a new direction to recreate such complex tissue architecture [2]. Here, wedesigned and replicated the complex AF intricacy using an extrusion-based 3D printing technology.For this purpose, we developed silk-carrageenan based bioink which was further thoroughlyinvestigated for rheological properties and printability. A disc-like angular-grid construct wasfabricated wherein the bioink filaments were deposited in a layer-by-layer fashion on top of othersmaking an angle-ply construct but in the horizontal plane. Thereafter, the construct was flipped by90° across the periphery resulting in printed filaments to be aligned vertically to the axismimicking the alignment of collagen fibers as seen in the native disc. Constructs were then putthrough a series of physiochemical testing including FESEM analysis for surface morphology andporosity analysis, FTIR for crystallinity, swelling and degradation studies. The 3D printedconstructs exhibited higher mechanical strength (~78 kPa) than the native porcine AF tissue (~37kPa). Thereafter, constructs were investigated for the biological assessment. Both the porcineprimary AF cells and adipose-derived stem cells (ADSCs) were seeded on the constructs. Cellsproliferated with time and deposited a sufficient amount of AF specific extracellular matrix asdepicted by histological, biochemical and gene expression studies. Finally, the fabricatedconstructs were checked for immunological response and were shown to be minimal-immunogenic whenimplanted in vivo subcutaneously in the rat model. Overall, the strategy adopted here may provide anew direction in fabricating of AF anatomical structure using the extrusion-based 3D printingtechnology.

Mr Vikas VermaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : JNKVV

JabalpurDesignation : PhD scholar

Chickpea (Cicer arietinum L.) is cultivated in 59 countries worldwide. With 23% protein in the dryseeds, this pulse crop provides for nutritional security in India, Pakistan, and Bangladesh amongmany other Asian countries and income security in some African countries. Asian demand for chickpeais expected to be 14 Mt by 2020, whereas African demand is projected to be ~1 Mt. However, globalyields of chickpea are low (factors limit the realization of potential yield due to the narrow genetic base of cultivatedchickpea (Cicer arietinum L.) in breeding programs. Hence, to assess the genetic variability andidentify promising introgression lines derived from wild Cicer species ICC 17264 (Cicer reticulatumL. ), IG 69978 (Cicer echinospermum L.) and desi landrace (ICC 4958), a set of 300 introgressionlines (ILs) of BC2F4 generation were evaluated in augmented design with four checks ICC 4958, JG 14,JG 130 and ICCV 10 during post-rainy season of 2018-19 at ICRISAT, Patancheru, India. Based on themean performance of ILs over control, promising lines were identified for earliness, seed size andyield traits. Based upon the per se performance 40 ILs produced significantly higher seed yield perplant compared with the best check, ICCV 10(22.85g) ICCP 173278,ICCP 172331,ICCP 172429,ICCP173334,ICCP 172147,ICCP 171053,ICCP 172350,ICCP 173170,ICCP 172079,ICCP 173210,ICCP 173668,ICCP173284,ICCP 171182,ICCP 173004,ICCP 171340,ICCP 173651,ICCP 173211,ICCP 172325,ICCP 171119,ICCP172738,ICCP 171500,ICCP 173159,ICCP 171081,ICCP 173181,ICCP 173287,ICCP 171038,ICCP 171750,ICCP171128,ICCP 173426,ICCP 173797,ICCP 173604,ICCP 173014,ICCP 173599,ICCP 171136,ICCP 171883,ICCP173230,ICCP 171547,ICCP 172281,ICCP 173019,ICCP 173677. These ILs might be tested in multilocationaltrials, to release as high yielding varieties of chickpea. Besides this, these ILs may be used asparents in hybridization programme to improve the yield and also to fight with malnutrition byproducing nutrient-rich varieties.

Dr Neera SharmaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Hindu

College, University of DelhiDesignation : Assistant

Professor

Abstract Chamki fever (also known as Acute Encephalitis) has emerged as a major health concern in India on large scale. Acute Encephalitis syndrome is characterized by acute onset fever leading to the brain inflammations, disorientation, mental disease, coma, and other neurological disorders. Even globally cases are growing which has emerged the concern to develop the potential vaccine against this viral infection1. In the present work, we have designed and optimized the potential multi-epitope subunit vaccine against envelope protein of Acute Encephalitis. We have employed the advanced immunoinformatics techniques to design the Cytotoxic T lymphocyte (CTL) epitopes and validated with various parameters including the high antigenicity and high immunogenicity. Molecular docking and molecular dynamics simulation have been performed to assess the molecular interaction of designed vaccine2. In results, we obtained the putative CTL epitopes (MHC restricted class-1) with high antigenicity and high immunogenicity. Multi-epitope subunit vaccine was formed by adjoining the known linkers AAY, GPGPG and Toxin B subunit of Vibrio cholerae (CTB) adjuvant. The designed vaccine was found to bind strongly with MHC-1 receptor, and host cell target toll-like receptor-2 (TLR2) with high docking scores; and also found to possess the optimal homing properties with high transported associated protein (TAP) affinity score. In addition, vaccine was studied for peptide dynamics using the CABS molecular dynamics simulation module; which confirmed the stable and specific binding of vaccine to the target receptors with lower RMSD value. This study gives the potential multi-epitope subunit vaccine for Indian Chamki fever; which can be further evaluated through in vitro and in vivo cell studies. Keywords: Acute Encephalitis; Multi-Epitope, Molecular Dynamics Simulation; Immunoinformatics. References 1. Wiwanitkit V. Development of a vaccine to prevent Japanese encephalitis: a brief review. Int J Gen Med. 2009; 2: 195–200.

Mr VIJAYA KARTHIK S VImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Kings college

of EngineeringDesignation : Ph.D - Full

Time Research Scholar

Abstract have been attached with this registration link as per the format given.

Prof SUSANTA MALLICKImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Mahatma

Gandhi collegeDesignation : Assistant

professor in Zoology

1Department of Zoology, Mahatma Gandhi College, Purulia, Pin-723130,West Bengal, India 2Department of Zoology, Sidho -Kanho -Birsha University, Purulia,. West Bengal, India 3Ecology and Ethology Laboratory, Department of Zoology ,University of Calcutta,35 Ballygunge Circular Road, Kolkata –700019, West Bengal ,India *E-mail: [email protected] Abstract The bats Pteropus giganteus (Brunnich, 1782) are confined to south - east Asia. Therefore, they are, now-a-days under serious threat of extreme heat during summer. In recent years, in course of studies on ecology of these bats occurring at Simla (23022? 44.20? N, 86038? 47.02??? E), Purulia, West Bengal, India we noted them to (i) change their hanging posture by keeping the back portion towards the sun, (ii) use their right wing as a fan to provide wind to the body, (iii) change the hanging spot little bit to enable the adjacent member to perform wing flapping ,(iv) select the roosting tree very close to a water body, (v) dip belly at the surface water of the water body and to lick the water from the body surface between 11:30 a.m. to 4:00 p.m. on the days when atmospheric temperature exceeded 420 C .On several occasions temperature raised up to 480C and the area was succumbed with loo, many pregnant and aged individuals failed to survive. It appears that the bats are at the verge of extinction because of extreme heat-induced hazard, at least in the arid zone of Purulia.

References: 1. Bergman.W.1978.Mus.Nat.Hist.6:20-25. 2. Iudica.C.A., F.J.Bonaccorso; G. Richard,1994, Bat Research News. 35(4):102(Abstr:). 3. Iudica.C.A; F.J.Bonaccorso.2003. Mammalia. 67(3):455-458. 4. Ratcliffe, F.N.1961. J.Mammal. 42:252-252

Ms Saheli BanerjeeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jadavapur

UniversityDesignation : Ph. D Scholar

Background: Macrovascular and microvascular complications and associated oxidative stress are the well known risk factors for diabetic mortality. The apoptotic markers and resulting DNA damage are taken as biomarkers of diabetes induced oxidative stress. Ayurveda classifies human population as combination of three Doshas- Vata, Pitta, and Kapha according to their basic constitution known as “Prakriti”. As per Ayurvedic classification Prakriti is a combination of three Doshas- Vata, Pitta, and Kapha. Individual’s basic constitution describes its predisposition and prognosis to disease status and also the treatment for disease. The Tridhoshas work in harmony to maintain good health in an individual. Elevation of the doshas beyond an individual’s threshold causes specific doshic disorder.

Aim: The aim of the study was to investigate the clinical, and biochemical variation which leads to apoptosis among the Prakriti groups having type 2 diabetes mellitus.

Methods: This study was performed with total seventy two participants (age 30-70 years), twenty four in each Prakriti groups having twelve of type-2 diabetes patients and twelve of healthy (without diabetes) participants. The differences in clinical, anthropometrical and apoptosis were observed in each participant.

Results: The study indicates that diabetic individuals mostly belong to the Vata groups was more prone to diabetic complications. A significant decrease in DNA content (p Conclusions: The people of Vata Prakriti are the most susceptible group. Prolonged hyperglycemia induces apoptosis which affects Vata prakrti most than the other two groups. These may help in creating personalized treatment of diabetes among individual Prakriti.

Mr Ziaul HasanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jamia Millia

Islamia Central UniversityDesignation : Research

Scholar

Abstract: Fungal lipase dependent processes are important virulence attributes. We explore Aspergillus niger lipase as a direct target of eugenol through spectroscopic techniques and compare results to Bovine Serum Albumin and lysozyme to comment on the selectivity of eugenol towards lipase. In activity assays, 50% inhibition of lipase was obtained at 0.913 mmoles/litre eugenol. UV-vis spectroscopy shows the formation of lipase-eugenol, Bovine Serum Albumin-eugenol and lysozyme-eugenol complex well below this concentration of eugenol. Eugenol binding caused a blue shift with Bovine Serum Albumin and lysozyme suggestive of compaction, and redshift with lipase. Negative ellipticity decreased with lipase but increased with Bovine Serum Albumin-eugenol and lysozyme-eugenol complexes suggesting the loss of helical structure for lipase and compaction for Bovine Serum Albumin and lysozyme. Binding of eugenol to lipase was strong (Ka= 4.7 x 106 M-1) as compared to Bovine Serum Albumin and lysozyme. A number of stoichiometric eugenol binding sites on lipase is found to be 2 as compared to 1.37 (Bovine Serum Albumin) and 0.32 (lysozyme). Docking results also suggest strong binding of eugenol with lipase followed by Bovine Serum Albumin and lysozyme. To conclude, eugenol is found to be good inhibitor and disruptor of the secondary and tertiary structure of lipase, whereas it's binding to Bovine Serum Albumin and lysozyme is found to be weak and less disruptive of structures suggesting selectivity of eugenol towards lipase.

Keywords: Eugenol; Aspergillus niger Lipase; Bovine Serum Albumin; Lysozyme, Molecular docking

Ms RAHNA PARAKKALImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : INSTITUTE FOR

COMMUNICATIVE AND COGNITIVE NEUROSCIENCES

Designation : JUNIOR RESEARCH FELLOW

Developmental language disorder (DLD), previously called specific language impairment, is aneurodevelopmental disorder defined as the failure to develop normal speech and language skills inthe absence of any environmental, medical or genetic impairments. It is the most common form oflanguage disorder prevalent in about 7% of school-age children. Learning disorders are subject tosubstantial genetic influences, but few causal mutations have been identified till date. Alterationsin epigenetic processes such as DNA methylation and histone modification could be important in thepathogenesis of these disorders based on their functions in gene regulation. DNA methylation plays acrucial role during neurodevelopment, regulating the transcriptional plasticity in developing brain.It directs the differentiation of cells in early development when neurological pathways are beinglaid down. Thus, alterations in DNA methylation could provide cues to the pathogenesis ofneurodevelopmental disorders. In this study, we examined any differential methylation of genes inindividuals with DLD compared to healthy controls. 12 individuals with DLD and 12 age- andgender-matched healthy controls were recruited for the study. The participants were between 5-10years of age and were drug-naive and seizure-free. Genome-wide methylation analysis was done usingInfinium Methylation EPIC BeadChip which covers over 850,000 genome-wide methylation sites.Differentially methylated loci and their corresponding genes were identified. Among the various locithat showed differential methylation, the genes that serve as modulators of the WNT signalingpathway deserve special mention. We observed hypomethylation of the genes (APCDD1, AMOTL1, LRP5,TMEM64, BANK1, VEPH1, WNT2B, TRABD2B) that act as negative regulators of WNT signaling andhypermethylation of a gene (MARK2) that is known to positively regulate WNT signaling. WNT signalingis fundamental for several neurodevelopmental and post-neurodevelopmental processes, such as thecentral nervous system (CNS) regionalization, neural progenitor differentiation, neuronal migration,axon guidance, dendrite development, synaptogenesis, neural plasticity and adult neurogenesis.Precise spatiotemporal regulation of WNT signaling is extremely important throughout the lifespan ofan individual. Any perturbation in WNT signaling pathway may trigger the advent of disorders relatedto the structure and function of the CNS. Alterations in WNT signaling have been reported in severalCNS disorders such as autism that are considered to be developmental in origin. This is the firststudy that indicates the impairment of WNT signaling in DLD which is a developmental languagedisorder. The findings need to be validated in a larger set of independent samples.

Ms SUMITHA PSImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : INSTITUTE FOR

COMMUNICATIVE AND COGNITIVE NEUROSCIENCES

Designation : PROJECT FELLOW

Autism spectrum disorders (ASD) are a group of complex neurodevelopmental disorders characterized by impaired social interaction, communication deficits, and restricted and repetitive behaviors. This childhood-onset disorder has a prevalence rate of 1 in 59. In spite of being a highly heritable disorder, the genetic architecture of ASD is highly complicated owing to its clinical heterogeneity. Most of the genetic studies of ASD till date have centered on Caucasian population, with very limited participation from Asian countries including India. In a family-based twin study, we attempted to identify the genetic variants of ASD by whole exome sequencing (WES). Five twin families, which includes three monozygotic and two dizygotic twins were recruited for this study. Among the monozygotic twins, two were concordant and one was discordant for ASD, while both the dizygotic twins were discordant for ASD. WES was done using SureSelectXT Human All Exon v5+UTRs kit on Illumina HiSeq 2500 to generate 2x100 bp sequence reads at 100x sequencing depth (~9Gb). After quality control and preprocessing, the reads were mapped onto a reference genome, followed by variant calling (SNPs, indels) and annotation. One of the most important findings in this study is the de novo mutations in olfactory receptor genes observed in four out of five twins. The following mutations were identified in the OR1D5, OR2T7, OR2T27, OR2T29 and OR51A2 genes, OR1D5: c.377C>T (p.T126I); heterozygous tolerated mutation OR2T7: c.35C>T (p.T12M); homozygous deleterious mutation c.332G>A (p.C111Y); heterozygous tolerated mutation OR2T27: c.359A>G (p.Tyr120Cys); homozygous deleterious mutation OR2T29: c.286G>A (p.V96I); heterozygous tolerated mutation OR51A2: c.867A>C (p.K289N); heterozygous tolerated mutation Interestingly, while mutations were present in both members of concordant twins, it was present only in the affected member of discordant twins. Individuals with ASD are known to exhibit atypical responses to olfactory stimuli. They exhibit decreased function for odor thresholds and odor identification. fMRI studies indicate that alterations in olfaction in ASD are rooted in the primary olfactory cortex. Previously, a genome-wide association study for ASD in Taiwanese Han population had revealed gene-based associations for OR2M3-OR2T5. The olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response for smell. Studies have demonstrated that olfactory communication plays an important role in establishing normal social behaviors and functions. Detailed studies to assess the role of the olfactory system in social disorders such as ASD are warranted.

Dr Rajnish KumarImage Delegate ID Theme Details


Research


University Uttar PradeshDesignation : Assistant

Professor

Abstract: Blood Brain Barrier (BBB) is collection of blood vessels with some unmatched set of properties of permeability that allow only a few types of drugs and compounds to have a passage through it. The BBB has an important role in maintaining equilibrium between intracellular and extracellular environment of brain. These vessels also help in tightly maintaining homeostasis (the movement of ions, molecules, and cells) between the blood and the brain. To develop the BBB permeability prediction model using random forest (RF) and to validate the developed model for BBB prediction on the independent dataset. The prediction of the BBB permeability was carried out using RF. The RF prediction algorithm is increasingly used in prediction and classification of non-linear datasets. A total dataset of 1011 compounds was divided into training and test set with 60:40 ratio. The prediction model was developed using RF algorithm with training set of 605 compounds. The descriptors used to develop the model were Molecular Weight, Rotatable Bond Number, Number of Hydrogen atom acceptor and donor, Vander Walls Surface Area and percentage of hydrogen, carbon, nitrogen and oxygen (H%, C% , N% & O%). The developed model was validated using test set of 406 compounds. The developed model was found to yield an accuracy of 80.66%. This preliminary study suggests that RF algorithm can be useful at the initial stages of drug design and development in prediction of BBB permeability of compounds.

References:

1. Saxena, D.; Sharma, A.; Siddiqui, M; Kumar, R. Blood brain barrier permeability prediction using machine learning techniques: An update. Curr Pharm Biotechnol. 2019 [Epub ahead of print] [DOI : 10.2174/1389201020666190821145346]

2. Castillo-Garit, J.; Casanola-Martin, G.; Le-Thi-Thu, H.; Pham-The, H.; Barigye, S. A Simple Method to Predict Blood-Brain Barrier Permeability of Drug- Like Compounds Using Classification Trees. Med Chem. 2017, 13 (7), 664 - 669

3. Couronné, R.; Probst, P.; Boulesteix, A. Random forest versus logistic regression: a large-scale benchmark experiment. BMC Bioinformatics. 2018, 19(1), 1-14

Ms Sonali DasImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR- Indian institute of chemical biologyDesignation : CSIR-Senior

Research Fellow

During transmission from poikilothermic sand fly gut to homoeothermic mammalian macrophage,Leishmania donovani recruits a plethora of cyto-protective heat shock proteins for persistenceinside mammalian macrophage. Therefore parasite proteins, essential for macrophage induced stresstolerance, are potential leads for anti-leishmanial therapeutics. We identified a putative ATPdependent protein of caseinolytic protease family, as an important interacting protein (IIP) forhost pathogen interaction network via Human- Leishmania donovani system level interactome analysis.LdHSP enriches in infected hamsters/ patient blood and amastigote like condition (37?C and 4.5-5.5pH). We generated transgenic parasites using both CRISPR-Cas9 and untranslated region (UTR) basedconventional knock out technology to identify its essential role in disease manifestation.Haplo-insufficient parasites (LdHSP+/-) were unable to alter induced nitric oxide synthase (iNOS)and arginase1 balance and escape the p38MAPK mediated nitric oxide (NO) toxicity in macrophages.Organ and blood parasite burden were reduced dramatically in LdHSP+/- parasites infected hamsters,along with enrichment of interferon-?, interleukin-12 and nitric oxide. Virulence phenotype of theheterozygous knock out parasites was restored by episomal add back of LdHSP allele as GFP fusedprotein. Interestingly we found LdHSP as a novel kinetoplastidial HSP having mitochondriallocalization peptide. We identified Ap5A, a synthetic nucleotide analogue as pharmaco-inhibitor ofLdHSP, by high throughput virtual screening method (HTVS). Ap5A exhausted parasite load frominfected macrophages and rescued parasites with overexpression of LdHSP regained its resistanceagainst Ap5A treatment. Thus, using both genetic as well as chemical impairments we confirmed LdHSPas a promising therapeutic target in visceral leishmaniasis (VL).

Ms Nidhi GoswamiImage Delegate ID Theme Details


Research


Nuclear Medicine and Allied Sciences (INMAS), DRDO


Nidhi Goswami*, Mohd Aleem, Kailash Manda Institute of Nuclear Medicine and Allied Sciences (INMAS), DRDO, Delhi-110054, India E-mail Id: [email protected] Abstract: Chronic pain associated comorbidities increase the complexity and basic understanding of pain. Preclinical pain models provide an understanding of the underlying molecular mechanisms and relevant therapeutic strategies. Assessment of chronic pain requires a comprehensive approach for the reproducibility of the result. The existing pre-clinical models of pain have two major limitations. First, the classical animal models of pain are chiefly dependent on the measurement of reflexive withdrawal from mechanical or thermal stimuli which are said to be suboptimal in terms of its poor match with human symptoms. Second, the lack of a severity scale based on the multiparametric test batteries. Chronic pain patients experience anxiety, depression, disability, cognitive dysfunction, sleep loss, social withdrawal, loss of libido and several other symptoms that could be modeled in the mice experiencing chronic inflammatory or neuropathic states. Therefore, considering the clinical pain-phenotypes, the pain severity needs to be quantified using a comprehensive behavioral test battery. The present study, while employing the sciatic nerve chronic constriction injury (SNCCI) model in C57BL/6J mice, conceptualized a behavioral test battery comprising three functional domains, the neuromuscular coordination, affective state, and cognitive function. Our data revealed that SNCCI model represents the disability-induced aberrant neuromuscular coordination and affective dysfunction but poorly defines the classical phenotypes of pain. Conclusively, all functional domains may get affected by chronic pain but to a varying extent. Therefore, quantification of pain severity requires a comprehensive behavioral test battery as conventional test protocols alone are not sufficient.

Mr Mohd AleemImage Delegate ID Theme Details


Research


Nuclear Medicine and Allied Sciences (INMAS), DRDO


Mohd Aleem*, Nidhi Goswami, Kailash Manda Institute of Nuclear Medicine and Allied Sciences (INMAS), DRDO, Delhi-110054, India Email Id:[email protected] Abstract: Traumatic Brain Injury (TBI) is one of the high priority areas of causality care practice within the military as well as the civilian population. Animal models of neurotrauma are valuable tools to understand the structural and functional outcomes of the brain following the TBI. The present study aimed to investigate the TBI-induced early changes in neuronal architecture, neurogenesis, neuroinflammation, and associated behavioral functions. For this purpose, C57BL/6J mice were subjected to Fluid Percussion Injury (FPI) and neurobehavioral changes were reported on day 7 post-FPI. Histopathological analysis showed that FPI significantly increases the number of dead neurons and leads to the thickening and fragmentation of axons in the ipsilateral cerebral cortex. A significant increase in the doublecortin immunoreactivity confirmed that FPI significantly augmented hippocampal neurogenesis. Similarly, the GFAP and TMEM immunoreactivity in the cortex and hippocampal regions showed a significant rise in reactive astrocytes and microglia following TBI. FPI exposed mice showed restlessness behavior in the open field test arena and a significant decrease in the grip strength. However, no significant changes in short-term memory, anxiety, and neuromuscular coordination were reported. Results from this study showed that mild TBI at 1.20 atm elicits a distinct pattern of structural and functional changes in the brain which nearly represent the clinical phenotypes.

Ms Deepti SharmaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : INMASDesignation : Senior

Research Fellow

Deepti Sharma1*, Lajpreet Kaur1, Himanshu Ojha1, Bal G. Roy2, Vinod Kaushik1 1Protectionand Decontamination Research Group, Division of CBRN Defence, INMAS, Timarpur, Delhi-110054 2Experimental Animal Facility, INMAS, Timarpur, Delhi-110054 [email protected] Abstract: An injury to skin can cause trauma to the patients. The three classes of traumatic wounds are: acute, cut and penetrating wounds. Some examples of traumatic wounds are knife stab, road accidents, animal bites, gunshots, burns, etc. In the presence of some complicated factors, the healing of these wounds can be delayed, but it is not well documented in literature. Some of the complications of delayed wound are infection, inflammation, tissue necrosis, etc. In the present work, liposomal hydrogel containing an anti-inflammatory agent ethyl pyruvate (EP) was prepared to check the healing efficacy in full- thickness excision wound model in Sprague Dawley (SD) rats. The topical hydrogel containing different concentrations of EP was prepared and characterized. The full thickness excision wound was created on the dorsal region of SD rats. The formulation was applied daily on wounds till healing. The wound contraction area and tensile strength of healed tissue was measured. The skin tissues were biopsied after healing of wounds for histopathological analysis. The prepared EP hydrogel formulations were homogenous in nature and stable. The wound treated with EP hydrogel formulations showed 17% faster healing compared to standard. The rate of period of re-epithelialization and wound contraction was greater in comparison to standard. The tensile strength of EP hydrogel treated skin was also higher than the standard implying the perfect arrangement of collagen fibres during scar remodelling. The histopathological analysis of hydrogel healed skin showed perfect alignment of epithelial cells, collagen fibres' arrangement and formation of new blood vessels and hair follicles. The prepared liposomal hydrogel of EP can be proposed as better healing agent for healing of traumatic wounds.

Dr CHANDRANI CHOUDHURIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : North Bengal

St. Xavier's CollegeDesignation : Assistant

Professor

Synthesis and accumulation of Pathogenesis-related (PR) proteins might play an important role inplant defence. Our study is based on elicitor mediated defence in Niger [Guizotia abyssinica (L.f.)Cass.] plant. Niger seeds produce excellent quality of vegetable oil, commonly known as ‘Ramtil’and are widely cultivated in Dooars region and other parts of India. Leaf blight disease of Nigercaused by Alternaria alternata can drastically reduce the yield. In this study, Niger plants wereinduced by four chemical inducers [2-aminobutyric acid (2-ABA); 2,1,3-Benzothiadiazole (BTH);2,3-Dihydroxybenzoic acid (DHB) and salicylic acid (SA)] and two botanicals (leaf extract ofAcalypha indica and Catharanthus roseus). After induction, Niger plants were challenged with A.alternata, the enzyme activities of Peroxidase (PO), Polyphenol Oxidase (PPO), ?-1,3 Glucanase(GLU), and Chitinase (CHI) were studied. Among all inducers studied, 2-ABA and Acalypha indica wasfound to be the best inducer for PO activity, whereas DHB showed maximum increase in PPO activity.But leaf extract of Catharanthus roseus was found to be most active biotic inducer for all defenceenzymes except PO. Inducible Isozymes pattern of enzymes when studied through native PAGE,differential expression of bands were observed for PO and PPO isolated from disease inoculated Nigerafter 2-ABA and C. roseus treatment respectively. Isozymes pattern of ?-1,3 Glucanase (GLU), andChitinase (CHI) were also studied. Results suggest that better plant defence enzymes could beinduced in Niger plant with the application of C. roseus leaf extract. Disease incidence was alsofound to be significantly reduced by application of 2-ABA and C. roseus extract. Our study confirmsthat inducible mechanism of disease resistance could be achieved through elicitation by syntheticphenylpropanoids as well as botanicals in Niger plant.

Ms PUJA SASHANKARImage Delegate ID Theme Details


Research


Botany, Sikkim UniversityDesignation : PhD Scholar

Puja Sashankar* & N. Sathyanarayana Department of Botany,Sikkim University 6th Mile,Tadong,East Sikkim *email:[email protected] Abstract:Rice is a widely grown staple food crop for half of the world’s population. Assam being one of the centres of origin has wide range of variation of rice cultivars. Among all the common cultivars, Joha rice of this region enjoys a top position in terms of popularity. It is well known for its unique aroma, superfine kernel, good cooking qualities and excellent palatability. However there has not been any genomic or transcriptomic studies in this cultivar except some preliminary breeding and tissue culture works. To improve the understanding of overall transcriptomic study and to find the major candidate genes in Joha rice, we sequenced the transcriptome of rice seeds (grain filling stage) and performed de novo sequence assembly in Aromatic cultivar Kon Joha (KJ1 & KJ2) from the North Eastern state of Assam and Ranjit (RA1 & RA2) variety as a Non-aromatic control.The data were stitched together to produce 53608, 57803, 75328 & 70110 transcripts with an N50 1287, 1239, 1673 & 1585 of 815, 791, 1033, 990 bp in KJ1, KJ2, RA1 & RA2 respectively. The data were then annotated with various databases [RefSeq non-redundant proteins (Nr),Swiss-Prot,Kyoto Encyclopaedia of Genes and Genomes (KEGG), A database of Orthologous Groups and functional annotation (eggNOG) and Gene Ontology (GO)]. There were total of 1059 genes differentially expressed in Aromatic rice where 928 were up-regulated and 131 were down-regulated. The differentially expressed genes were functionally annotated using Blast2Go and Mercator annotation tools. The genes annotated reveals the existence of potential candidate genes for resistance to pest & disease, abiotic stresses like Cold, Salt and Drought, Aroma and Grain quality. The transcriptome data and analysis presented here lay the foundation for further research into this important crop of Northeast India.

Mr NITESH KUMARImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Department of Genetics and Plant Breeding,

BCKV, West bengalDesignation : Research

Scholar

Rice (Oryza sativa L.) belongs to the family Poaceae and is widely grown in Asia under the rainfedconditions. The shift in temperature coupled with limited water availability to the crops hasaffected drastically the crop physiology as well as the production technology. Keeping in view ofthese challenges, the 9 genotypes (3 highly tolerant, 3 moderately tolerant and 3 susceptible fordrought tolerance) were crossed in 9X9 diallel cross to produce 36 F1’s (excluding reciprocals)during Kharif-2014 at Agricultural Research Farm, Institute of Agricultural Sciences, Banaras HinduUniversity, Varanasi, U.P. Half of the F1’s seeds along with the parents were grown at theResearch Farm of CRRI, Cuttack, during off-season 2014-15 for generation advance to F2. All the 36F1’s, F2’s, their Parents along with two standard check varieties namely Sahbhagi and ShushkSamrat, were grown at RGSC, Barkachha, Mirzapur in Kharif 2015 under water stress conditionfollowing Compact Family Randomized Block Design with three replications. Analysis of variance intreatment was significant for the 19 characters in the study, indicating that there was sufficientvariation in the treatments. The ratio of dominance to recessive genes (KD/KR) was more than one forall the traits except plant height, stay green and relative water content, indicating an excess ofdominant genes in the parents. Over-dominance was observed for traits viz. no. of effectivetillers/plant, test weight, spikelet fertility %, and panicle length. Inbreeding depression variedwith the crosses and traits and found to be relatively more under water stress conditions. The yieldtraits like panicle length, number of grains per panicle, 1000 grain weight, and grain yield perplant showed an optimum range of inbreeding depression. The promising crosses under drought stressconditions were Nagina-22 × SARJOO-52, Nagina-22 × Vandana, and BPT-5204 × MTU-7029.

Dr sonia chadhaImage Delegate ID Theme Details


Research



Professor

Partial Purification of Acid Phosphatase from germinating chickpea (Cicer arientum) seeds Mohu Sah and Sonia Chadha* Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus Malhour (Near Railway Station) Gomti Nagar Extension, Lucknow-227105 (INDIA) *Corresponding [email protected] Abstract- Phosphatases (EC 3.1.3.2) are an important class of enzymes that catalyse the hydrolysis of several phospho-monoesters and phosphoproteins. Phospho-monoester hydrolysis is an important process in biological systems linking energy metabolism and metabolic regulation. Depending on the optimum pH required for their activity, phosphatases may be classified as acid phosphatases or alkaline phosphatases. They are widely distributed in plants and animals. They provide inorganic phosphate to the growing plants during seed germination. In the present study an acid phosphatase was isolated and partially purified from an extract of germinating chickpea (Cicer arientum) seeds. Chickpea seeds used in the present study were purchased from the local market, Lucknow, Uttar Pradesh. The seeds were soaked in sterile distilled water and then incubated at 28°C for 48 h to induce germination. A 10% extract was prepared in ice cold extraction buffer (0.05M sodium acetate, pH 5.0). The enzyme was precipitated by 80% ammonium sulphate and dialyzed against the extraction buffer with constant stirring under ice cold conditions for 24 hrs. The enzyme assay was performed spectrophotometrically at 405nm using p-nitrophenyl phosphate (p-NPP) as substrate. Acid phosphatase was purified by 3.9 fold with a specific activity of 1.3 U/mg of protein. The molecular weight of the enzyme as determined by SDS-PAGE was found to be 39 kDa.

Dr Somali SanyalImage Delegate ID Theme Details


Research



Professor

Interaction of smoking and XPC polymorphism in risk modulation of oral cancer in North Indian population Kumud Nigam, Somali Sanyal* Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow-226028, India (AIB Communication No. AIB/RA/2019/297) *[email protected]

Abstract: Oral cancer is the most common cancer among the Indian men and the second most common cancer among the Indian women. Such high incidence of oral cancer in India is due to consumption of tobacco in different form including smoking of cigarette. Smoke of tobacco contains different carcinogens which causes DNA damage. Such DNA damage if remain unrepaired due to faulty DNA repair system can cause mutation and development of cancer. Different studies have reported the effect of smoking and DNA repair gene on development oral cancer. In the present study we aimed to check the interaction of XPC polymorphism with smoking in risk modulation of oral cancer. Total of 372 subjects from North India including 300 healthy controls and 72 patients of oral cancers been genotyped for the XPC A/C polymorphism with PCR based or PCR –RFLP based method. Risk of oral cancer has been estimated among smokers and non smokers who were stratified within different genotypes of XPC polymorphisms. Estimated risk was expressed with Odds Ratio and a P value less than 0.05 considered significant. We observed that individual who were smokers and carrier of variant allele genotypes (AC and CC) for XPC A/C polymorphism were at 3 fold higher risk (p value= 0.01, OR=2.97 , 95% CI 1.29-6.86) to develop oral cancer compared to individual who were smokers but do carry the C allele (AA genotype). This observation indicates that C allele of XPC A/C polymorphism interacts with smoking and significantly increases the risk of oral cancer in North Indian population. Key Words: Oral cancer, Smoking, XPC, Polymorphism

Ms Minakshi DebImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : University Of


Scholar

Isolation and optimisation of diesel degradation by bacterium isolated from Siliguri and its probable application as a plant growth promoter

*Minakshi Deb, Dr. Arindam Bhattacharjee

Department of Microbiology, University of North Bengal, Raja Rammohanpur, Darjeeling, West Bengal, India, Pin:- 734013

[email protected]

Abstract:

Petroleum consists of hydrocarbons like alkanes, napthenes, asphaltics and other liquid organic compounds. Wide scale production and its global application has made it a leading contaminant of the environment. Recent reports of oil contamination in marine environment and agricultural lands to large extent have drastic effects on the environment thereby distorting their biodiversity, and this has culminated largely towards the productivity of soil. Hence the problem should be addressed immediately. The present study focuses on reclamation of oil contaminated soil using bioremediation approach so that the contaminated soil can be reclaimed effectively and also the agricultural scenario can be improved in an eco-friendly organic way. It involves application of the isolated strain as a plant growth promoter for improving agricultural activities at the reclaimed sites at the same time. The bacterial strain AB1 was isolated from the diesel contaminated sites of Siliguri, West Bengal. The strain showed maximum homology with Serratia odorifera (accession number KR019684) according to phylogenetic analysis. Optimisation of growth conditions by Response Surface Methodology indicated that the strain could effectively degrade diesel by 10th day of incubation under the optimised growth conditions. Study for auxotrophic growth concluded that the isolate was an auxotroph as it failed to grow in absence of external carbon source. Studies for various plant growth promoting properties showed the bacterial strain to be positive for indole acetic acid production, phosphate solubilisation, nitrogen fixation and siderophore production. Thus, this strain can be used not only for the bioremediation of oil contaminated soils but also to promote the growth of economically important crops.

Dr Sayali MukherjeeImage Delegate ID Theme Details


Research


University Uttar Pradesh Lucknow Campus


Yadvendra Shahi, Sayali Mukherjee* Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus Lucknow-226028, India (AIB Communication No.- AIB/RA/2019/291 ) *Corresponding author: [email protected]

Abstract- Squamous cell carcinoma of the oral cavity is one of the most common cancers in the world and accounts for 47% of all cancers in the Indian subcontinent.Types of cancer with high rates of mortality and morbidity all over the world oral cancer is believed to be preceded by oral potentially malignant disorders (OPMD), a well-established precancer stage, that can be visually detected in the oral cavity .Oral potentially malignant disorders are early clinical features that are thought to undergo histopathological and molecular changes enroute to invasive oral cancer OPMD (leukoplakia, erthyroplakia and oral sub-mucous fibrosis) are primarily caused by lifestyle risk exposures (tobacco smoking, smokeless tobacco use, betel quid chewing and alcohol. These factors cause gene alteration in oncogenes and tumor suppressor gene which encodes for an increase risk of oral precancerous lesions. One such gene related to these malignancies and inflammation is Interleukin-6 (IL6) which encodes a cytokine protein involved in inflammation, immune homeostasis and oral pathogenesis. The aim of this study was to evaluate the association between IL6 -596G/A promoter gene polymorphisms and risk of oral pre cancer among Indians. Single nucleotide polymorphism IL-6 gene was genotyped in oral pre cancer patients (n=50) and healthy controls (n=70) by PCR-RFLP method. Genotype and allele frequencies were analyzed by chi-square test and strength of associations by odds ratio with 95% confidence intervals. Frequency distribution of IL6 (-596) G/A gene polymorphism was significantly associated with oral precancer patients in comparison to healthy controls (OR: 3.14, CI: 1.47-6.86; chi square=9.14, p=0.001). This study shows the genotype GA of IL6 (-596) G/A gene polymorphism was significantly associated in the development for the oral precancer lesions.

Dr Hamendra Singh ParmarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Devi Ahilya

UniveristyDesignation : Assistant

Professor

In search of cost efficient drugs for better treatment of the diseases prevailing our country and the Globe, we have conducted various experimental works in last few years including on diabetes mellitus, obesity, Alzheimer’s disease and cancer. In our published research work we have performed experimentation on both in vivo and in vitro biology. We have observed that most of the diseases are cross linked with the inflammatory pathways of various kinds and in fact, whereas, disease like cancer also shown to have defects in metabolism. We have observed that diabetes and obesity phenotypes, as well as amyloid beta induced neurodegeneration can be treated well with anti-inflammatory drugs such as aspirin. We have also observed that the Th2 cytokines which are known to be associated with allergic conditions and thought to be antagonistic with Th1 cytokines that participate in progression of diabetes may leads to the induction of pre-diabetic condition in animals. This further consolidated the role of inflammation in the progression of various diseases. Similarly, we also observed that specific and non-specific cyclooxygenase-2 inhibitors (COX-2) also having efficiency on acetylcholinesterase inhibition and inhibition of amyloid beta oligomers and fibril formation. Based on structural similarity, we demonstrated that naringin (flavonoid present in orange peels) and glimepiride sulfonamide (a drug intermediate) may exert DPP-IV inhibition and anti-diabetic benefits to the animals. We are also working on metabolic modulation of cancer cell lines through which we can address chemo-resistance, viability, apoptosis, migration and stemness of the cancer cells. Based on our own and other reports, we recommend that on one hand innovative drugs are required to treat the deadly diseases more efficiently, on the other hand, we can reduce the cost of therapy with better clinical outcomes by inclusion of pre-existing cost efficient drugs having proven track record of safety and efficacy on some other disease phenotypes.

Mr DEEPAK KUMARImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : MDU

ROHTAKDesignation : RESEARCH

SCHOLAR

The medicinal properties of plant species have made an outstanding contribution in the origin andevolution of many traditional herbal therapies. More than 80% of the world's population relies ontraditional medicine for their primary healthcare needs. These traditional knowledge systems havestarted to disappear with the passage of time due to scarcity of written documents and relativelylow income. Plants used for traditional medicine contain a wide range of substances that can be usedto treat chronic as well as infectious diseases. The medicinal plants have regained a widerecognition due to escalating faith in herbal medicine in view of its lesser side effects comparedto allopathic medicine. But today more than 800 million hectare of land are salt affected. Salinityand soil nutrient deficiencies are the main abiotic stress factors which reduce plant production inthe semi-arid and arid areas around the world. By keeping all these in view the present the presentresearch has been planted with the objectives to In vitro establishment of seedling, to culture andmaintain of explants on MS medium with different growth regulators, to study the effect of NaCl oncallogenesis, differentiation and antioxidant potential of in vitro differentiated material.

Ms Shadma AfzalImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Motilal Nehru

National Institute of Technology Allahabad


Background: Plants being sessile entities are subjected to a variety of abiotic and biotic stress conditions. Oryza sativa L. commonly known as Rice is one of the most consumed cereal in the world and is deemed a model crop for tolerance studies. Mutants are an imperative genetic reserve, which can help as an informative basis of natural disparity. Multiple environment testing facilitates the recognition of constant genotypes of rice mutants for adverse abiotic stress conditions. Aim: To study the effect of different abiotic stresses viz. drought, salinity, nanoparticles and heavy metal conditions in early (BM6), mid-early (BM9) and late (BM30) flowering Pusa basmati mutants. Methods: EMS induced BM6, BM9, and BM30 mutants were assessed for potential study of stress tolerance under limited water, salinity and high zinc conditions by testing for plant growth (biophysical and biochemical) traits, as well as cytotoxicity and genotoxicity determination assay via MTT (Majumdar et al., 2017) and fluorescence microscopy (Liljegren 2010) methods in root tissues of the mutants. Result: The stress treatments suppressed the plant growth, being maximum for 150 mM ZnSO4 followed by 150 mgL-1 NPs > 150 mM NaCl > 150mM mannitol. There was a slight variation among the genotypes, significant susceptibility and better performance for stress tolerance was observed in BM9 mutant. BM9 showed minimum suppression in biophysical and biochemical parameters, highest antioxidant enzyme activity and a higher percentage of cell viability was reported. The fluorescence intensity levels of stress in different zones of roots exposed to stress types were: elongation zone > meristem zone > mature zone, weak fluorescence in mature zone when compared with the other zones, and the concentration in meristem zone was more or less the same as the one in elongation zone. Lignin accumulation was detected in roots of treated plants showing that stress exposure has resulted in deposition Conclusion: Based on the deluge of research findings, it is clearly indicated that stress has a devastating effect on the growth, development, and physiology of the plant. These mutants are a valuable resource for varietal advancements and to determine genes for tolerance to multiple abiotic stresses. This study can additionally assist in the fastidious detection of stress-tolerance genes in this vital crop. References: 1. Majumdar, S.; Guha, T.; Kundu, R. Bio Protoc. 2017, 7, 22. 2. Liljegren, S. Cold Spring Harb. Protoc. 2010, 1.

Ms PRATIBHA .Image Delegate ID Theme Details


Research

Category : BiologyOrganisation : IIT DelhiDesignation : Research

Fellow

Peat moss is most commonly used substrate for growing horticultural crops under nursery condition due to its high nutrition exchange capacity, water holding capacity, salt buffering capacity and aeration qualities. Peatlands, natural habitats of huge biodiversity of organisms, are major CO2 sink and maintains quality of ground water. Apart from environmental concern, peat availability is not cosmopolitan. Due to high freight cost, peat usage is less competitive in countries where its availability is scarce or zero. To address this problem, in recent years scientists had experimented with various organic waste for replacing/reducing the use of peat moss. Coir pith is one such alternative widely used in India. It is derived from the mesocarp tissue or and husk of coconut (Cocos nucifera L.) fruit. It is light in weight, has good aeration, good water holding capacity. But its nutritional qualities are poor than Peatmoss. Hence, to fulfill the nutrient scarcity various organic amendments were analyzed previously. Aim of the present study is to investigate the effect of amending the potting mix with 3 deoiled cakes (ground nut, sesame and neem cake) on the morphological growth parameters (root length, shoot length, fresh weight, dry weight, number of leaves, leaf area, chlorophyll content) of tomato seedlings under nursery condition. A replicated pot experiment was conducted at Gramodaya Parisar, Indian Institute of Technology, Delhi during summer season of 2017-2019. Neem cake was found to have significant positive effect on the all the growth parameters up to 2.5 % amendment. While sesame and ground nut cake were found to be inhibitory to the growth of tomato seedlings at lower concentrations (2.5 %). As neem deoiled cake is abundantly available in India, its possible utilization to improve the potting mixture quality should be explored.

Ms PREETI SIROHIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Motilal Nehru

National Institute of Technology Allahabad


Phytic acid is phosphorylated carbohydrate which have potential anticancer activity. The objective of this study was to elucidate the inhibitory mechanism of the phytic acid on Human colon cancer cell line. To evaluate the anticancer property of phytic acid we treated the cancer cells with the various concentrations (100µg/mL, 200µg/mL, 300µg/mL, 400µg/mL and 500µg/mL) of phytic acid and perform MTT assay, LDH assay, and Flow cytometry analysis using SW480 colon cancer cell line. The findings were further validated by Real time PCR. MTT analysis revealed that the cytotoxicity of phytic acid on cancer cell line increases as the dose and time dependent manner with the increasing concentrations of phytic acid at different time intervals (24h, 48h, 72h). Maximum 50% cytotoxicity was observed at a concentration of 500µg/mL (IC50) at 72 h in comparison to control (5-FU) treatment. The results of MTT assay were further validated by the help of flow cytometric analysis. The flow cytometric analysis of treated samples showed that the rate of cell death of cancer cell line increases with the increase in the concentration of phytic acid. The rate of cell death was recorded upto 80% in the case of higher concentration of phytic acid after 72hrs of treatment. The findings of Real time PCR revealed that the target gene CDK1 (cell cycle regulators) was downregulated which support the flow cytometry results of cell cycle arrest, further target genes ATXN1 and c-Myc were upregulated and CTNNB1 was down-regulated. The study demonstrated that the phytic acid can reduce cell proliferation and induce apoptosis through inhibition of Wnt/beta-catenin signaling pathway and it can be recommended that phytic acid rich crops in routine diet have the ability to reduce or prevention of colorectal cancer. Keywords: Phytic acid, cytotoxicity, apoptosis, anticancer property, Real time PCR, Human Colon cancer cell line SW480

Mr vandit shahImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : L. M. College

of PharmacyDesignation : B. Pharm

Triple-negative breast cancers (TNBC) are defined by a lack of expression of estrogen, progesterone, and ERBB2 receptors. This subgroup accounts for 25% of all types of breast cancer and for a higher percentage of breast cancer arising in African and African-American women who are premenopausal. Because of the absence of specific treatment guidelines for this subgroup, triple-negative breast cancers are managed with standard treatment; however, such treatment leaves them associated with a high rate of local and systemic relapse. Hence, in-order to tackle this situation and decrease the amount of deaths, due to TNBC world-wide, we hypothesized a novel combinatory therapy that involves DNA-methylating agents in combination with PARP1 inhibitors. Which, per-forms a dual role of causing a severe DNA damage via. Alkylating the DNA and cross-linking the same. The homologous recombination and DNA repair machinery of cells employs the PARP1 protein to tackle the SSB and prevents its extension into DSB, ultimately leading to Cell death. Hence, by using PARP1 inhibitors in addition to DNA-methylating agents is most certainly the treatment regimen that would enable us to treat the patients with TNBC and also increase the time and reduce the frequency of tumor’s local and systemic relapse.

Mr PRASHANT R. KHANDAGALEImage Delegate ID Theme Details


Research


Life SciencesDesignation : Ph. D. Scholar

Human DNA polymerase delta (Pol?), a holoenzyme consisting of p125, p50,p68 and p12 subunits, playsan essential role in all the three DNA transaction processes. Herein, using multiple physicochemicaland cellular approaches we found that the p12 protein forms a dimer in the solution. In vitroreconstitution and pull-down of cellular Pol? by tagged p12 authenticates pentameric nature of thiscritical holoenzyme. Further, a consensus PCNA interacting peptide (PIP) motif at the extremecarboxyl terminal tail and a homodimerization domain at the amino-terminus of the p12 subunit wereidentified. Our mutational analyses of p12 subunit suggest that 3 RKR 5 motif is critical fordimerization that facilitates p12 binding to IDCL of PCNA via its PIP motif 98 QCSLWHLY 105.Additionally, we observed that oligomerization of the smallest subunit of Pol? is evolutionarilyconserved as Cdm1 of S. pombe also dimerzes. Thus, we suggest that human Pol? is a pentamericcomplex with a dimeric p12 subunit; and discuss implications of p12 dimerization in regulatingenzyme architecture and PCNA interaction during DNA replication.

Dr Lovely MahawarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jai Narain Vyas University, JodhpurDesignation : Assistant

Professor

Abstract

Cadmium is the major redox inactive metals which released into an environment through agricultural land from farming, industries and finally reduces the development process of plants by forming reactive oxygen species (ROS). The current study explores the protective role of Heme oxygenase 1 (HO 1) in scavenging ROS against Cd stress in seedlings of Eruca sativa and its co-relation with Ascorbate Peroxidase (APX) enzyme. Hydroponically acclimatized seedlings of Eruca sativa var. DPY BKP 98 were subjected to CdCl2 stress at varying concentrations ranging from 10 µM to 150 µM. After 96 hours of treatment the stressed plant were harvested to study the cellular homeostasis and Cd tolerance mechanism by analyzing the growth, stress parameters and enzymatic as well as non enzymatic antioxidants. At 125 µM concentration a significant increase in APX activity was recorded which were 2.98 and 2.05 folds higher than control in leaves and roots respectively. The overall activity of HO 1 was also found to be highest at these concentrations which were 2.13 folds higher than 100 µM concentration in roots. The highest APX activity with HO 1 imitated the decline in LPX and ROS at 125 µM concentration. From the present investigation it is concluded that both the enzymes are working concurrently to remove H2O2. A collateral benefit of understanding the APX and HO 1 antioxidant mechanism would be of significance in crop plant improvement as well as in developing new scientific strategies to genetically enhance the stress tolerating ability of the crop.

Key words: Heme oxygenase 1, Ascorbate Peroxidase, Cadmium. Reactive Oxygen Species, Eruca sativa

Mr SAYAK BHATTACHARYAImage Delegate ID Theme Details


Research



Research Fellow

Marine sponges play some vital roles in the coral reef. However, very few studies have been conducted on sponge diseases due to adverse conditions under the deep sea. Webster et al. (2002) [1] first reported the infection of Great Barrier Reef sponge Rhopaloeides odorabile by pathogenic strain NW4327 which was identified as Pseudoalteromonas agarivorans [2]. The presence of collagenase enzymes were also investigated but not in detail [3]. Later, these collagenase enzymes were purified, identified and characterized in detail by both lab-based experiments and in silico methods [4, 5]. Ultrafiltration, size exclusion chromatography and anion exchange chromatography were carried out to purify the collagenase enzymes. SDS-PAGE was performed to examine the approximate molecular weight of the purified protein bands and then MALDI-TOF MS/MS was carried out to determine the molecular weight of the purified single protein bands. The activity of these protein bands was carried out by gelatin and collagen zymography methods and azocoll assay. Characterization was carried out with inhibitors and metal ions studies. Detection of physicochemical parameters, secondary and tertiary structure prediction, molecular docking study, molecular simulation study, and BLAST search were carried out by in silico methods to characterize the collagenase enzymes in detail. Our study identified two novel collagenase enzymes. One of them was identified as TonB dependent receptor (TBDR) which was showing collagenase activity in the presence of both Ca2+ and Zn2+ ions whereas another was identified as U32 peptidase which was showing collagenase activity in presence of only Ca2+ ion. Amino acid comparison of other U32 peptidases from other terrestrial pathogenic microorganisms with U32 peptidase from sponge pathogen clearly revealed that unique amino acids were present in the catalytic site of U32 peptidase of P.agarivorans NW4327. Molecular simulation study indicated that the stability of U32 peptidase increased while it was bound with both collagen and Ca2+ ion. Molecular docking study and total Gibbes free energy calculation indicated that TBDR bound with type IV collagen more strongly than type I collagen. Type IV collagen is present in the marine sponges. The presence of signal peptide, absence of transmembrane helices and presence of TBDR in the cell-free supernatant clearly indicated that TBDR was secreted out of the cell where U32 peptidase was also secreted but U32 peptidase was devoid of the signal peptide. In future, we will focus disease progression mechanism in detail and examine functions of other virulence factors of NW4327.

Dr Satabdi GangulyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICAR-Central

Inland Fisheries Research Institute

Designation : Junior Research Fellow

The Indian shad hilsa (Tenualosa ilisha), a commercially important food ?sh rich in oils, enjoys high consumer demand in the South Asian countries due to its unique ?avour and culinary properties. The rivers Hooghly in India and Padma in Bangladesh are two important sources of hilsa fisheries. Although both the rivers share the Bay of Bengal stock, hilsa from river Padma enjoys higher consumer preference. In this context, a comparative analysis of the flesh quality attributes in hilsa in terms of nutritive value (proximate, amino acid, fatty acid and mineral composition) from the rivers Hooghly and Padma was carried out. The amino acid composition was analyzed by HPLC, fatty acid by GC/MS and mineral by ICP-MS. The results showed that Hooghly hilsa is nutritionally superior to Padma hilsa considering the medium size category fish (500-800g); in terms of oil content, essential amino acids (lysine, valine, leucine) and ?-3 PUFAs (C18:3, C20:4, C20:5, C22:6). However, expression of some genes related to fatty acid metabolism was found to be up-regulated in Padma hilsa. Therefore, to get a holistic picture of the lipid metabolic pathways as well as effect of different riverine habitats; if any, on the nutritional composition of hilsa from both the rivers, a comparative liver transcriptome analysis was carried out using next generation sequencing under Illumina platform (HiSeq 2500). After de novo assembly and annotation, a total of 1, 00,489 unigenes were identified in the liver trascriptome of hisa. Comparative liver transcriptome analysis also showed that the key genes for LC-PUFA biosynthesis (ELOVL5, FADS2, CPT1) were up-regulated in Hooghly hilsa; indicating its higher LC-PUFA biosynthesis potential compared to Padma hilsa. Thus, the present study generated new knowledge on unknown nutritional facets of hilsa and strengthened the knowledgebase for future research on this important food fish that is targeted for domestication.

Ms TANIMA CHATTERJEEImage Delegate ID Theme Details


Research


CalcuttaDesignation : Research

fellow

Type 2 Diabetes mellitus has emerged as major health issue in this millennium and researchers areattempting to explore new targets to develop novel therapeutic strategy. Most often Type 2 diabetesmellitus (T2D) is accompanied by dyslipidemia increasing the risk factor for cardiovascular (CVD)complications. Enhanced oxidative and nitrosative stress appear to be the major risk factorsunderlying insulin resistance, dyslipidemia, ?-cell dysfunction and T2D pathogenesis. Recentlyautophagy has been identified to be a promising defense mechanism against stress mediated celldamage regulating tissue homeostasis, cellular quality control, energy production promoting cellsurvival. In this study, we have attempted to explore the role of autophagy in T2DM subjects with orwithout dyslipidemia in Peripheral blood mononuclear cells and insulin resistant HepG2 cellsutilizing flow cytometric platform, confocal microscopy and molecular biology techniques likewestern blotting, immunofluorescence and real time PCR. In case of T2DM with dyslipidemia higherpopulation of autophagy positive cells was detected compared to patients with only T2DM, which mighthave resulted due to higher stress. Autophagy was observed to be triggered both by oxidative andnitrosative stress, revealing a novel finding of this research. LC3 puncta was observed in PBMC andperiphery of HepG2 cells in case of diabetic and dyslipidemic condition. Increased expression ofATG5, LC3B and Beclin supports the autophagic pathway in both PBMC and insulin resistant Hep G2cells. Upon blocking autophagy by 3-methyl adenine (3MA), the apoptotic cell population increasedsignificantly. Autophagy was also been evidenced to control oxidative stress mediated up-regulationof inflammatory markers like IL-6, TNF-?.To conclude, this study elucidates autophagy to present aprotective role in case of diabetes mellitus with dyslipidemia. In the present global scenario, ourwork demands great impact on the studies of insulin resistance and dyslipidemia. This studysignificantly provides new strategy for developing novel drugs for diabetic dyslipidemic subjects byenhancing the autophagic activity.

Dr Shalini DattaImage Delegate ID Theme Details


Research


Statistical InstituteDesignation : Ramanujan

Fellow

Abstract: Introduction: Gastric cancer (GC) is the second most common cancer among men and third-most among females in Asia and is the second most common cause of cancer-related deaths in India 1. The MSLN gene encodes a 71-KD precursor, which is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein that is cleaved into a 40-KD membrane-bound fragment called MSLN (mesothelin) 2 3 4. Several studies increasingly show that aberrant MSLN expression plays an active role in both malignant transformations of tumors and tumor aggressiveness by promoting cancer cell proliferation, contributing to local invasion and metastasis, and conferring resistance to apoptosis induced by cytotoxic agents. Moreover, the elevated expression of MSLN was correlated with poorer prognoses in patients with gastric adenocarcinoma in TCGA cohort. Here we sought to delineate the role of mesothelin in gastric adenocarcinoma. Materials and methods: Tumor samples were obtained with informed consent from GC patients at IPGMER with informed consent. Tissues were fixed with 10% neutral formalin, embedded in paraffin and HE stain and IHC were done. RNA were isolated and gene expression was done using sybreen taking ?actin as endogenous control. Stable AGS cell lines that are overexpressing MSLN are made by transfecting the cell lines with MSLN expression plasmid. Cell proliferation and invasion ability were determined by MTT, colony formation, and cell migration. Results: We performed immunohistochemical analysis and gene expression of 50 gastric cancer tissues. The expression of MSLN was significantly increased in most of the tumor tissues. In contrast, most normal tissues express low MSLN. We observed that MSLN overexpressing stable AGS cell line promotes cell proliferation compared to wild type AGS cell line. Discussion: Our results indicate that mesothelin gene as well as protein expression is very high in gastric adenocarcinoma which is helping in invasion metastasis and hence, enhancing the aggression of the disease. Mesothelin is a promising target for immune-based therapy, specifically for mesothelioma and pancreatic and ovarian cancers that have high levels of mesothelin expression. In future, the gastric adenocarcinoma patients with high mesothelin expression can be considered for such therapy.

Mr Ninad NagarkarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : PGTD Biochemistry, Nagpur

UniversityDesignation : research

scholar

Drug Repurposing of selected Non Steroidal Anti Inflammatory Drugs against Oral Cancer with Phytochemical Supplementation Ninad Nagarkar1*, Archana Moon1 PGTD Biochemistry, RTM Nagpur University, LIT Campus, Nagpur * contact author: [email protected] Abstract: Drug repurposing is the futuristic way of harnessing the unused potential of drug molecules. Since enormous amounts of time (around 10 – 15 years) and investment (nearly $ 2 billion) goes into creating a market-ready drug, drug repurposing holds the promise to curtail the cost of clinical trials to some extent (nearly $ 30 – 40 million) and getting the drug ready in less time (3 – 4 years) as compared to de novo manufacture. It is estimated that repurposed drugs are approved in much shorter timelines (3-12 years) and at about 60% of the cost of typical development. While approximately 10% of new drug applications gain market approval, repurposed drugs approach approval rates near 30%. Non Steroidal Anti Inflammatory Drugs (NSAIDs) such as aspirin, mebendazole, diclofenac, ibuprofen, acetaminophen, cetrimide, etc. modulate COX 1 and COX 2 pathways and further downregulate its cancer related pathways. The authors intend to demonstrate a potent repurposing therapy composed of NSAIDs supplemented with therapeutic phytochemicals against oral cancer. The incidence of oral cancer in Indian population is most prominent in the lower socio-economic strata. Hence, oral cancers remain neglected, the late detection and late initiation of treatment cause most fatalities. To test the efficiency of repurposing an In silico and in vitro investigation of a suitable and effective drug repurposing formulation will be done on oral squamous cell carcinoma (OSCC). To test the efficacy of the formulations in a dose dependent manner as a repurposed therapy routine anticancer study such as MTT assay will be performed.

References: 1. Ashburn, Ted T., and Karl B. Thor. Nature reviews Drug discovery 3.8 (2004): 673. 2. Moore, Malcolm A., Asian Pac J Cancer Prev 11.Suppl 2 (2010): 49-66. 3. Piazza, Gary A." Pharmaceuticals 3.5 (2010): 1652-1667. 4. Alvarez, Juan C. Current opinion in chemical biology 8.4 (2004): 365-370.

Ms Deeksha SaxenaImage Delegate ID Theme Details


Research


University Uttar Pradesh Lucknow Campus


Abstract

Background: Blood Brain Barrier (BBB) is a collection of blood vessels with some unmatched set of properties of permeability that allow only a few type of drugs and compounds to have a passage through it. The BBB has an important role in maintaining equilibrium between intracellular and extracellular environment of brain. These vessels also help in tightly maintaining homeostasis (the movement of ions, molecules, and cells) between the blood and the brain. Aim: To develop the BBB permeability prediction model using random forest (RF) and to validate the developed model for BBB prediction on independent dataset. Methods: The prediction of the BBB permeability was carried out using RF. The RF prediction algorithm is increasingly used in prediction and classification of non-linear datasets. A total dataset of 1011 compounds was divided into training and test set with 60:40 ratio. The prediction model was developed using RF algorithm with training set of 605 compounds. The descriptors used to develop the model are Molecular Weight, Rotatable Bond Number, Number of Hydrogen atom acceptor and donor , Vander Walls Surface Area and percentage of hydrogen, carbon, nitrogen and oxygen (H%, C% , N% & O%). The developed model was validated using test set of 406 compounds. Conclusion: The developed model was found to yield accuracy of 80.66%. This preliminary study suggests that RF algorithm can be useful at the initial stages of drug design and development in prediction of BBB permeability of compounds.

Keywords: Blood brain barrier, machine learning, random forest, permeability prediction, rotatable bond number

References: Saxena D, Sharma A, Siddiqui MH, Kumar R. Blood brain barrier permeability prediction using machine learning techniques: An update. Curr Pharm Biotechnol. 2019 [Epub ahead of print] [PMID: 31433750]

Castillo-Garit, Juan & Casanola, Gerardo & Le Thi Thu, Huong & Pham The, Hai & Barigye, Stephen. A Simple Method to Predict Blood-Brain Barrier Permeability of Drug- Like Compounds Using Classification Trees. Medicinal Chemistry. 2017; 13 (7): 664-669 [PMID: 28185535]

Couronné R, Probst P, Boulesteix AL. Random forest versus logistic regression: a large-scale benchmark experiment. BMC Bioinformatics. 2018; 19(1): 270. [PMID: 30016950]

Ms Chhavi SharmaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Amity Institute

of Microbial Biotechnology, Amity University, Noida


Microbial fibrinolytic proteases serve as novel and potent thrombolytic agents for the treatment ofthrombosis. The objective of this study was the evaluation of in vitro thrombolytic potential of athiol-dependent purified fibrinolytic protease by Bacillus cereus RSA1 (NCBI Accession number:MK288105). The bacterial strain was screened for fibrinolytic activity on sterile skimmed milk agarplates and fibrin plates. The growth parameters were statistically optimized using Plackett BurmanDesign and Response Surface Methodology with 30.75 U/ml protease production. The crude fibrinolyticprotease was further purified using precipitation and chromatographic techniques which resulted in2.32 fold purification and 33.11% recovery. SDS-PAGE revealed 70 KDa molecular weight offibrinolytic protease. The protease was thermostable (30-60°C) and exhibited broad pH stabilityrange (5-10) with maximum activity at 50°C and pH 8, respectively. Fibrinolytic activity of theprotease was completely inhibited by TCEP-HCL (non-thiol reductant), while 2-fold increase inactivity was observed with DTT and ?-mercaptoethanol indicating its thiol-dependent nature. Theeffect of protease inhibitors and activators was investigated wherein protease activity was slightlyinhibited by Fe3+, Fe2+, Ca2+, Co2+, Hg2+, Mg2+, Cu2+, K+, Na+ while it was enhanced by Zn2+ andMn2+.The enzyme kinetics revealed Michaelis constant (Km) of 4 mg/ml and Vmax 115 U/mg. Thetherapeutic applicability of the protease when tested for blood clot dissolution by its comparativeanalysis with a marketed drug (Myokinase), was found highly significant with complete blood clotdissolution within 4h of incubation. In conclusion, the medicinal application of fibrinolyticprotease can be acclimatized to public health amenities which can serve as an efficient alternativefor blood clot dissolution.

Ms Vaishnavi RathiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sir Ganga

Ram HospitalDesignation : Research

fellow

DETECTION OF PLASMA-DERIVED EXOSOMAL PROTEIN BIOMARKERS IN GLIOMA PATIENTS Vaishnavi Rathi, Kirti Chauhan, Satnam Singh Chhabra1, Rajesh Acharya1, Ansul Gupta, Samir. K. Kalra, Sunila Jain2, Rashmi Rana

Department of Research, Sir Ganga Ram Hospital (SGRH), New Delhi-110060 1Department of Neurosurgery, Sir Ganga Ram Hospital (SGRH), New Delhi-110060 2Department of Histopathology (SGRH), New Delhi-110060 Email id: [email protected] Background: Exosomes (EXOs) in glioma are distinctly strong intermediator with ability for flipping the action of neighbouring cells. Their release into the circulation can potentially inform about status of the tumor. In-depth characterization of plasma-derived exosomes has been limited by challenges in isolating EXOs from protein-abundant biological fluids. We implemented a novel single-step density gradient flotation workflow for efficient and rapid isolation of highly enriched circulating EXOs from plasma samples. Effective methods for glioma are still in the waiting and there is strong need for standardization and characterization of highly accurate blood-based method. Methods: We assess the importance of the exosome proteins as biomarkers for glioma patients. Proteins extracted from plasma-derived EXOs of 40 glioma (grade I, II, III, IV) and 20 healthy subjects were analysed. NTA and TEM confirmed the presence of plasma-derived EXOs isolated by differential centrifugation. FACS analysis characterized exosomal proteins tetraspanins CD63, CD9 and CD81. Results: The result shows that the level of CD63, CD9 and CD81 were highly expressed in glioma (grade I, II, III, IV) patients in comparison to controls. Conclusion: Our study performed the first characterization of tumor-derived EXOs from human glioma (I, II, III and IV) to expand latest information on the molecular mechanisms of cancer progression and to propose potential tumor biomarkers. Keywords: Glioma, CD9, CD63, CD81 tetraspanins, NTA, FACS, Western Blot. References: 1. Swartz MA et al. 2012. Cancer Res 72: 2473–2480. 2. Pavlou MP et al. 2010. J Proteomics 73: 1896–1906.

Ms Kirti ChauhanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sir Ganga

Ram HospitalDesignation : PhD Student

IDENTIFICATION OF EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III (EGFR VIII) EXPRESSION IN MENINGIOMA PATIENTS Kirti Chauhan, Satnam Singh Chhabra1, Rajesh Acharya1, Ansul Gupta, Samir. K. Kalra, Sunila Jain2, Rashmi Rana, Department of Research, Sir Ganga Ram Hospital (SGRH), New Delhi-110060 1Department of Neurosurgery, Sir Ganga Ram Hospital (SGRH), New Delhi-110060 2Department of Histopathology (SGRH), New Delhi-110060 Email id: [email protected] Background: Meningiomas are the most common type of intracranial tumors of central nervous system and account for approximately 36% of all primary tumors of CNS. According to the WHO grading system and histological studies it is classified into different grades: grade (I) benign, grade (II) atypical, grade (III) anaplastic or malignant. There are certain mutations and alterations of tumor suppressor genes and chromosomal aberrations leads to the tumor formation and its progression in meningiomas. Epidermal growth factor receptor (EGFR) play an important role in the regulation of cell division and tumor growth and its over expression responsible for the stimulation of angiogenesis, cell survival and metastatic proliferation. EGFR variant III is the most common mutation has been already reported in glioblastoma but not yet reported in meningiomas and other type of tumors. Methods: The main aim of this study is to determine expression of EGFR variant III in different grades of meningioma using primarily Immunohistochemistry and also via other techniques such as FACS (fluorescence activated cell sorting) and western blotting. Results: Results shows the expression of EGFR variant III is highly expressed in benign meningioma (grade I) as compare to atypical (grade II) meningioma. These results could be considered in large number on cohort as possible diagnostic /prognostic biomarker and somehow influence the treatment. Conclusion: EGFR expression is greatest in benign meningiomas and may serve a potential target for therapeutic intervention with selective EGFR inhibitors. Keywords: EGFR VIII, Meninigima, IHC, Western Blot. References: 1. Smith JS, Lal A, Harmon-Smith M, Bollen AW, McDermott MW: J Neurosurg 2007, 106:1034-1040. 2. Bianco R, Damiano V, Gelardi T, Ciardiello F, Tortora G: Curr Pharm 2007, 13(33):3358-3367. 3. Andersson U, Guo D, Malmer B, Bergenheim AT, Brännström T, Hedman H, Henriksson R: Acta Neuropathol 2004, 108(2):135-142.

Ms Manisha PritamImage Delegate ID Theme Details


Research


University LucknowDesignation : Ph.D scholar

Designing of self-assembled peptide nanoparticles as vaccine candidates against Plasmodium falciparum

Manisha Pritam1, Garima Singh1, Suchit Swaroop2, Satarudra Prakash Singh3 and Akhilesh Kumar Singh1* 1Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow, India-226028 2Department of Zoology, Lucknow University, Lucknow, India- 226007 3Department of Biotech and Genome, Mahatma Gandhi Central University, Bihar-845401 *Contact author’s mailing address: Email: Akhilesh Kumar Singh: [email protected]

Abstract: Malaria is a parasitic disease mainly caused by Plasmodium falciparum. According to latest report of WHO, in 2017, 219 million cases and 4,35000 deaths were reported from all over the world. Despite decades of research there is no licensed vaccine available in the market for malaria. So, there is great need to develop a vaccine with high efficacy. In the present study, we focused on designing of self-assembled peptide nanoparticles (SAPN) as potential vaccine candidates against malaria. The experimentally reported T-cell epitopes were retrieved from IEDB database against P. falciparum and immunoinformatics approach was used to design an epitope ensemble that cover 97.72% and 93.01% of population coverage for World-wide and India, respectively. For development of SAPN monomer, we used His-tag, MHC Class I epitopes (NQMIFVSSI, YLINKHWQR, TPYAGEPAPF, KVSDEIWNY, RPRGDNFAV), MHC II epitopes (DAEVAGTQYRLPSGKCPVFG, LKELIKVGLPSFENL and ALLIIPPKIHISIEL), linkers, pentameric domain and trimeric domain. The secondary and tertiary structure analysis was done by using PSIPRED 4.0 and RaptorX, respectively. The physicochemical property of designed SAPN was predicted by using Expasy ProtParam tool. So, the designed SAPN may further use as effective vaccine candidates against Plasmodium falciparum which can save time, labour and cost in development of vaccine.

References: 1. Negahdaripour, M.; Golkar, N.; Hajighahramani, N., Kianpour, S.; Nezafat, N.; Ghasemi, Y. Biotechnol Adv. 2017, 35, 575-596. 2. Zeigler, D.F.; Gage, E.; Roque, R.; Clegg, C.H. NPJ Vaccines. 2019, 4, 1-8.

Ms Garima singhImage Delegate ID Theme Details


Research


university, lucknowDesignation : PhD scholar

Analysis of experimentally reported epitopes of leishmania donovani for worldwide prevention of Visceral Leishmaniasis Garima Singh1, Manisha Pritam1, Monisha Banerjee2, Satarudra Prakash Singh3 and Rajnish Kumar*1 1Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus-226028 2Department of Zoology, Lucknow University, Lucknow Uttar Pradesh 226007 3Depratment of Biotech and Genome, Mahatma Gandhi Central University, Bihar-845401 *Corresponding author email: [email protected]

Visceral leishmaniasis commonly known as kala-azar is a parasitic disease endemic in parts of tropics, subtropics, and southern Europe. It is categorized as neglected tropical disease spread by bite of Phlebotomine sand flies. Globally, around 0.2–0.4 million cases of VL arise each year, out of which 90% occurs in following six countries including India, Bangladesh, Brazil, Ethiopia, Sudan and South Sudan. IEDB (immune epitope database) contains experimentally reported epitopes of Leishmania donovani having 19 MHC class I and 13 MHC class II epitopes. In this study we developed an epitope ensemble set comprising 5 epitopes which consists 3 MHC class I (AMAGNPVVI, DAMENPLSL and SMDSEYAHL) and 2 MHC class II epitopes (ILLVGDRAKDQVVNLHLMI and IGGIGTVPVGRVE). Population coverage analysis resource tool of IEDB predicted that the developed epitopes ensemble set showed 63.19% combined world-wide coverage. Hence, there is an urgent need to screen the whole genome of Leishmania donovani in order to identify effective vaccine candidates, which can be further implemented in designing targeted vaccine against visceral leishmaniasis. References: 1. Kone, A.K.; Niaré D.S.; Piarroux, M.; Izri, A.; Marty, P.; Laurens, M.B.; Piarroux, R.; Thera, M.A.; Doumbo, O.K. J Parasitol Res. 2019, 9282690. 2. Alvar, J.; Vélez, I.D.; Bern, C.; Herrero, M.; Desjeux, P.; Cano, J.; Jannin, J.; den Boer, M. PLoS One. 2012,7, e35671.

Mr YADVENDRA SHAHIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : AMITY

UNIVERSITYDesignation : research

scholar

Abstract- Oral squamous cell carcinoma is the most common malignancy of the oral cavity. ?any environmental factors (smoking and alcohol consumption) and genetic factors(oncogenes and suppressor genes) are implicated in the development of oral cancer. Several factors related to angiogenesis, inflammation and thrombosis have also been associated with oral oncogenesis. Tumor necrosis factor alpha (TNF-?) which was previously implicated in cancer, inflammation and thrombotic events are encoded by TNF-? genes. TNF-? is a proinflammatory multifunctional cytokine produced by macrophages. It plays an important role in the regulation of immune response since its increase after traumatic injury generates a cytokine cascade resulting in activation, proliferation and hypertrophy of mononuclear and phagocytic cells. TNF-? has been implicated in the pathogenesis and progression of various malignancies The pro-inflammatory cytokine tumor necrosis factor- ? (TNF- ?) is a central mediator of the immune response involved in a wide range of immuno-inflammatory and infectious diseases. The aim of this study was to evaluate the association between TNF- ? ?308G/A(rs1800629) promoter gene polymorphisms and risk of oral cancer among Indians. Single nucleotide polymorphism TNF- ? gene was genotyped in oral cancer patients (n=40) and healthy controls (n=35) by PCR-RFLP method. Genotype and allele frequencies were analyzed by chi-square test and strength of associations by odds ratio with 95% confidence intervals. Frequency distribution of TNF- ? ?308 G/A gene polymorphism was significantly associated with oral cancer in comparison to healthy controls (OR: 6.67, CI: 2.34-18.99; chi square=13.78, p=0.0002). Therefore, the study shows the genotype GA of TNF- ? ?308G/A gene polymorphism was significantly associated with the risk of developing oral cancer.

Keywords: TNF- ?, PCR-RFLP, oral cancer

Ms Riddhi PrabhaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Institute


Biodegradation of Acrylamide by Acrylamidase Synthesized from Nitrile Amide Degrading Bacteria BITNR017 and Analysis of Biodegraded Product through FTIR and HPLC Riddhi Prabha and Vinod Kumar Nigam* Department of Bio-Engineering Birla Institute of Technology, Mesra, Ranchi – 835215 (Jharkhand), India * Corresponding author: [email protected] Abstract: Background: Acrylamide, a toxic compound present in the ecosystem is a carcinogenic, neurotoxic, genotoxic, and teratogenic in nature (World Health Organization, 1985). Its extensive practice in numerous industrial processes leads to environmental pollution. So, it is essential to detoxify the acrylamide to non-toxic acrylic acid from the surroundings by the microbial means –acrylamidase (Jebasingh et al., 2013; Lakshmikandan et al., 2014; Bedade and Singhal, 2017). Aim: The aim of the present study was to investigate biological degradation of toxic contaminant acrylamide using nitrile amide degrading bacteria. The acrylamide degrading bacterium was isolated from the soil of the hot spring, Surajkund, Jharkhand in the mineral base medium supplemented with acrylamide (5 mM) followed by its screening to recognize the ability of degrading acrylamide. The optimization of few different factors was evaluated by using one- factor at a time method along with the analysis of biodegraded product through FTIR and HPLC. Result: Bacteria BITNR017 were selected as the suitable bacteria with acrylamidase capability which degrades the toxic acrylamide at temperature of 45? C with neutral pH and thermal stability (upto 60 °C). The acrylamidase ability and degradation of acrylamide was further determined by FTIR and High Performance Liquid Chromatography (HPLC) which showed similarity of biodegraded product to the reference. Based on biochemical tests, the selected isolate was identified as Gram negative bacteria and may belong to Pseudomonas. Thus, the acrylamidase can be used in the bioremediation of acrylamide from the food systems and environment in a green manner. Keywords: Acrylamide; Acrylic acid; Biodegradation; Acrylamidase; FTIR; HPLC. References: 1) Lakshmikandan, M., Sivaraman, K., Elaiya, Raja S., Vasanthakumar, P., Rajesh, R.P., Sowparthani, K., Jebasingh, E.- S.J. Int. Biodeterior. Biodegrad. 2014, 94, 214–221 2) Jebasingh, E.-S.J., Lakshmikandan, M., Rajesh, R.P., Raja, P. Int. Biodeterior. Biodegrad. 2013, 85, 120–125 3) Bedade, D.K., Singhal, R.S. Appl. Biochem. Biotechnol. 2017, 182 (2), 570–585 4) World Health Organization. 1985, 49, 1

Mr ANIRUDDHA DASImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : INSTITUTE

OF LIFE SCIENCESDesignation : JUNIOR RESEARCH FELLOW

Abstract: High-throughput RNA sequencing and novel bioinformatic pipelines have uncovered thousandsof circular (circ)RNAs, although the functions of only a few of them are known. CircRNAs areconventionally identified and quantified by the presence of the backsplice junction sequence thatcan be amplified using divergent PCR primers flanking the junction. However, circRNAs forming frommultiexonic precursor RNAs may contain different combinations of exons and/or introns arising fromalternative splicing, while the backsplice junction sequence is the same. To be able to identifycircRNA isoforms bearing the same backsplice junction but containing different internal sequences,we developed a method termed circRNA-Rolling Circle Amplification(circRNA-RCA). This method detectsfull-length circRNA sequences by performing reverse transcription (RT) in the absence of RNase Hactivity and by allowing the RT reaction to progress until the full circle has beenreverse-transcribed at least once. Amplification of the tandem repeats of full-length cDNAs derivedfrom the circRNA followed by full-length circRNA PCR using a forward primer spanning the backsplicejunction sequence and reverse primer exactly upstream of the forward primer, and sequencing can theninform about the size and internal sequence of the various circRNA splice variants. Using thismethod, we identified novel circRNA splice variants that were otherwise predicted computationally. The novel splice variants were further predicted to associate with different subsets of targetRNA-binding proteins and microRNAs, supporting the notion that different circRNA splice variants canhave different functional outcomes. In sum, the method circRNA-RCA allows accurate identificationof full-length circRNA sequence, offering unique insight into their individual function.

Mr ANISH KUMAR TIWARIImage Delegate ID Theme Details


Research



SCHOLAR

Abstract In nature genetic modification mainly occurs due to mutation. Without mutation, the breeding programme of plants is not possible. There is a number of chemicals, biological, physical processes that are available to induce mutation but recently ion beam technology emerged as a new form of physical mutagen for the induction of mutation in plants, to produce new verities of various plants, in place of X-rays, Y-rays, and neutrons. Micro RNA is the family of small noncoding which plays a significant role in regulating development and stress responses in the plant. To identify the specific miRNA that underlies the biological effect of ion beam radiation. The main aim of ion beam induced mutation in plant breeding is to modify and develop Novel mutants (such as drought resistance, high productivity, high nutrient use efficiency, etc.) and their related genes. This process is made possible due to high RBE (Relative Biological Effectiveness) of ion beams of growth inhibition, fatality, etc. The most effective LET value for inducing mutant sectors without causing severe damage of genetic material is lies between (30-110 KeV/µm). Results awaited but previous studies suggested that the ion beam generates high mutation frequency (mutation causes deletion of several base pair long genetic material which results in irreparable DNA damage) as well as wide mutation spectrum. Keywords: ion beam, mutation, RBE, LET, mi RNA. References 1. Shikazono, N., Suzuki, C., Kitamura, S., Watanabe, H., Tano, S., and Tanaka, A. (2005) Analysis of mutations induced by carbon ions in Arabidopsis thaliana. J. Exp. Bot., 56, 587–596.

Ms Ankita ChakravartyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Delhi

Technological UniversityDesignation : Student

Jaiphal (Myristica fragrans Houtt. or nutmeg) is classified botanically as a member of the family‘Myristicaceae’ and is cultivated for two spices : nutmeg from its seed and mace that forms theseed covering. It belongs natively to Banda Islands in the Moluccas of Indonesia and is cultivatedin Southern India especially in Kerala. Since ages, traditional knowledge of using jaiphal iscommonly used for treating of various diseases such as cold and coughs, anti inflammatory antidiabetic and strong antioxidant activity. In today’s world, like pharmaceutical industry, foodindustries are also focused on development of substances that naturally contain some healthbenefits. The present study was done to investigate the bioactive metabolites from the fruit ofMyristica fragrans. Elemental analysis was done by ICPMS, functional group analysis was assessed byFTIR, surface morphology was examined by SEM, moisture content was evaluated by oven dry method, andnutritional estimation by RP-HPLC was done. 30 elements showed significant amount in the powderedsample such as Au, Ag, Mg, Cr, Fe, Mn etc. Functional groups such as alkyl halides, alkenes,aldehyde, saturated aliphatic, aliphatic amines, primary and secondary amines etc. Presence ofvarious functional groups such as amines, nitrites, and aldehydes leads to phytochemical screeningof the sample which are responsible for various therapeutic effects such as anti inflammatory, anticancerous, anti diabetic etc Surface morphology was analyzed at different resolutions such as 500x,2kx, 5kx which showed rough and bounded morphology of the sample. The curative effects for curingvarious human diseases could be the result of presence of various bioactive constituents in them.The results from the above study showed the presence of various important elements in the samplewherein, Au and Ag are of utmost important as antioxidants, other minerals such as Fe plays a keyrole in hemoglobin.

Ms SAPNITA SHINDEImage Delegate ID Theme Details


Research


VishwavidyalayaDesignation : PhD Scholar

Abstract: Pleurotus ostreatus is one of the most nutritive edible mushroom and is being cultivatedglobally infering a profitable agrobusiness. Substrate optimisation is the most critical step in theproduction of good yield. Agrowaste being economical has been a noble option for substrateutilisation. Present research aims to find out the most suitable substratum for the cultivation ofPleurotus ostreatus along with deciphering the altered nutritional pattern. The agricultural wastesubstrates used for optimistion were Suggarcane Baggase (SB), Wheat Straw (WS), Rice Straw (RS) indifferent ratio (75:25 and 60:40). We observed the highest biological yield in RS with the maximumnumber of cap formation, 2.6cm stipe length, 6.92cm cap diameter, 143.5g economic yield and 26.49gdry weight followed by yield of SB and WS (144.97, 78.66 and 100.97g respectively). The highestprotein content was found in SB (27.52%), while highest lipid content 7.69% SB in combination with75% SB and 25% WS, ash content 14.97% highest in WS in combination with 75% WS and 25% RS and 50.27%highest carbohydrate content was observed in SB. Although, mushroom has grown faster in SB and inits combinational substrate, yet the biological efficiency is found highest in RS. Hence, it can beconcluded that, rice straw can be the most suitable substrate for cultivation of oyster mushroom.

Dr RAJNIKANT DIXITImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CMR-National Institute of malaria Research

Designation : Scientist-D

The blood feeding mosquitoes are regarded as deadliest animal since they transmit many infectiousdiseases such as Dengue, Chikungunya, Malaria etc. Though the evolution and adaptation tohost-seeking and blood feeding behaviour in adult female mosquito is crucial for the diseasetransmission, but the molecular mechanism is not well known. A well-coordinated neuro-olfactoryregulation is essential for a successful host seeking and blood feeding event in adult femalemosquitoes. Earlier we demonstrated a synergistic action of olfactory OBP/Ors derive host seekingbehavior properties. Here we report a dynamic relationship of mosquito brain engagement to regulateblood feeding and gut metabolic activities for blood digestion. A RNAseq based global profilingresulting gradual modulation in response to blood meal, suggested an active brain engagement tomaintain physiological homeostasis. An exclusive induction of oxidoreductase associated proteins, wecorrelate with a multi organ metabolic switch response following rapid blood meal uptake. Atranscriptional profiling of brain transcripts in response to blood meal suggested a guidedneuro-action is enough to manage the brain-distant organ communication. A parallel modulation of gutneuro-peptide receptors indicated an independent auto regulatory action of gut metabolic switch.Furthermore, an altered neuro transmitters level in response to gut bacterial removal evidenced ofgut-brain axis relationship. Conclusively, for the first time we demonstrate that in parallel toblood meal induced gut-metabolic switch responses, not only activate gut’s own secondary brain,but also engages principle brain centre via gut microbes calling in the mosquito Anophelesculicifacies.

Ms MASHU TRIVEDIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR- CIMAP

Designation : PROJECT ASSISTANT-II

Oxidative stress is an unbalanced redox state of an organism. This ambiguous state is a result of either production of high amount of reactive oxygen species (ROS) or defective detoxification system of the body. Aging is process of progressive decline in functional and structural well being of the body. Aging is usually accompanied by neurodegenerative diseases in which the neurons get damage. Occurrence of neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease is due to aggregation of toxic proteins like amyloid beta and alpha-synuclein respectively. Elevated levels of ROS hasten the process of toxic protein accumulation and elevate the damage .Caenorhabditis elegans represents a powerful system for the identification of components involved in aging and neurodegeneration. Phytomolecules that counteract cellular stresses have shown to alleviate aging and neurological diseases pathologies. In the present study we evaluate the effect of ethanolic extract of Baccopa monneri (BME) on various bio-markers of aging and for its anti oxidant, neuroprotective effects using C. elegans wild type and transgenic model system. Imaging, behavioural, lifespan and various biochemical assays showed that BME extended lifespan, decreased mitochondrial ROS levels, lipid accumulation as well as lipofuscin levels. Alleviation of protein toxicity by mitigating ?-synuclein and amyloid beta accumulation in disease model was observed. We observed a significant change in mRNA expression of sod-3 and gst-4. BME also caused upregulation of cha-1 and unc-29 genes regulating acetylcholine synthesis and receptors respectively. Therefore, the above results prove BME as a potential curative regime for neuroprotection and graceful aging.

Mr Mohit KumarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Deptt. of

Pharmaceutical Sciences, HNB Garhwal (A Central) University


Enhancement of dissolution and diffusion properties of BCS class IV drug Amphotericin B by developing Supersaturable Self Emulsifying Drug Delivery System Mohit Kumar*, Lalatendu Mohanty, Abdul Faruk Department of Pharmaceutical Sciences, Hemvati Nandan Bahuguna Garhwal University, (A Central University), Srinagar (Garhwal), Uttarakhand-246174 Corresponding author’s e-mail: [email protected]

The present study was focused on the development of the Supersaturable self emulsifying delivery system (S-SEDDS) of the drug Amphotericin B for oral delivery using HPMC E5LV and PVP K3 as a polymeric precipitation inhibitor (PPI) in two different ratios. The objective of the work was to study the drug content, in-vitro release profiles, in-vitro diffusion study and to develop a formulation with increased drug loading, better solubility, permeability and oral bioavailability. The excipients used were oleic acid as oil phase, tween 80 as surfactant and a 1:1 blend of propylene glycol, PEG 400 as co-surfactant. All the excipients were selected on solubility basis and data was plotted on Ternary phase diagram, an optimum ratio of the excipients was selected. Analysis of various physical and pharmacokinetic parameters for all the formulations were performed and it was found that the used PPI in S-SEDDS formulations showed better drug content, solubility and drug diffusion release profile than that of the SEDDS formulations. Droplet size analysis performed showed size of nanometric range (37- 728 nm). Zeta potential analysis showed stable (+15 to +17mV) property of the systems. It was observed that S-SEDDS formulation F2 prepared with Amphotericin B and HPMC E5LV in 7% amount exhibited good in-vitro dissolution and diffusion properties and may lead to better oral bioavailability of the Amphotericin B.

References: 1. Bandyopadhyay, S.; Katare, O.P.; Singh, B. Development of optimized supersaturable self-nanoemulsifying system of ezetimibe: effect of poly and efflux transporters. Expert Opin. Drug Deliv. 2014, 11(4), 479-92. 2. Bhattacharyya, A; Bajpai, M. Development and evaluation of a self-emulsifying drug delivery system of amphotericin B. Asian Jour. of Pharma. 2012, 6 (9), 124-9.

Mr YESU RAJAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Central University of Tamil NaduDesignation : Research

scholar

Fourier-transform infrared spectroscopy (FTIR) spectroscopy has been proven and accepted powerfultool to study the functional group analysis of biological components [1]. It enables thenon-perturbative, label-free extraction of biochemical information, assessment of cellfunctionality, which requires low cost and nano-litre sample for analysis [2]. Most haematologyresearch virtually ignores the important role of the real time analysis of healthy human bloodclotting (no additive anticoagulant) with respect to time and storage temperature. In the presentwork, we have studied the functional group changes of the normal healthy subject during the naturalcoagulation process in an ambient temperature using FTIR spectroscopy. Blood was drawn from ahealthy adult volunteer from clinical heath centre, and FTIR spectrum was recorded in the rangebetween 4000-400 cm^-1 for every 1min until the blood coagulate. Blood functional groups of water,amide I & II, amino acids, lipids and glucose, etc.. are identified. In general, whole bloodcontains functional groups whose bond lengths are mostly in the range between 0.96 Å to 1.54 Å[3].These inter-atomic interactions are weak, the bond lengths decreased during the coagulation process,and we observed that the blood cells became closer forming a semisolid that confirms coagulation.

Dr Rajan Kumar PandeyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Central University of Rajasthan

Designation : INSPIRE SRF

Visceral leishmaniasis (VL) is caused by the parasites of the Leishmania donovani complex, leads tothe death of 20,000-40,000 people from 56 affected countries, worldwide. To date, there is not asingle available vaccine candidate to prevent the visceral leishmaniasis infection, and treatmentonly relies upon expensive and toxic chemotherapeutic options. Consequently, the immunoinformaticsapproach was applied to design a multi-epitope based subunit vaccine to enhance the humoral as wellas cell-mediated immunity. The constructed vaccine candidate was further subjected to evaluation onallergenicity and antigenicity and physicochemical parameters. Later on, di-sulfide engineering wasperformed to increase the stability of the vaccine construct. Also, molecular docking and moleculardynamics simulation studies were performed to check the binding affinity and stability of TLR-4 tovaccine construct complex. Finally, codon optimization and in silico cloning were performed toensure the expression of the proposed vaccine construct in a microbial expression system.

Ms VINOTHA VISWANATHANImage Delegate ID Theme Details


Research


UniversityDesignation : Ph.D Scholar

Mosquitoes are crucial thread for millions of people and animals worldwide; they act as vector forvarious deleterious diseases .The use of synthetic insecticides to control mosquitoes can causeharmful effects on non-target organism, human health and environment. In the present study, greensynthesis of zinc oxide nanoparticles using aqueous rhizome extract of Acorus calamus by reductionof Zn+ ions from zinc acetate solution has been studied. The synthesized zinc nanoparticles werecharacterized by UV, XRD, FTIR, SEM and TEM. Rhizome extract and synthesized Ah-ZnO NPs wereevaluated against the larvae of Aedes aegypti and Culex tritaeniorhynchus. Compared to aqueousextract, synthesized Ah-ZnO NPs showed higher toxicity against Ae. aegypti, and Cx.tritaeniorhynchus with LC50 and LC90 values of 33.26 and 90.90 ?g/mL, and 16.36 and 89.70 ?g/mL,respectively. Moreover, the investigations towards the systemic effect of tested substances ontreated larvae were evaluated. In addition, the level of total protein and acetylcholine esterasewere found to be significantly decreased as compared with the control. Overall, this study provesthat A. hexapetalus is a potential bio-resource for stable, reproducible nanoparticles synthesis andAh-ZnO NPs are used as an efficient tool against the control of larval populations.

Ms Monali MISHRAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NCAAE

Designation : Phd Scholar

Neisseria gonorrhoeae is causative of the sexually transmitted disease gonorrhoeae. As of now thereis not yet a clinical approach that can prevent its infection. Hypothetically, the most promisingapproach would be to find one or more gonococcal vaccines, but none has been successfully developedto the stage of validation. Therefore, as of now, management through antibiotic only is in practice.But, then, due to excess use of antibiotics, several resistant strains have arisen. Reversevaccinology has been successfully applied to many infectious diseases. We applied a computationalapproach to identify and develop a new vaccine for reducing the burden of human suffering fromgonorrhoeae. In the present study, reverse vaccinology approach has been adopted for the successfulprediction of candidate vaccine targets in N. gonorrhoeae virulent strain NCCP11945. Proteome setwas retrieved for this strain of N. gonorrhoeae, which contains 2163 proteins. Out of them, 37trans-membrane proteins were screened using CELLO and PSORTb. Among these 37 proteins, 11 wereidentified by VaxiJen v 2.0 as the potential antigenic proteins. In the further screening nineproteins were identified as potential vaccine candidates. Among them one surface-exposed novelantigenic epitope “VQYAPKDNS” of membrane protein WP_012504064.1 was predicted to induce bothB-cell and T-cell immune responses. This peptide can be used for the development of exclusivepeptide vaccines. This being a humble beginning, the approach requires further designing of thevaccine and subsequent validation of the peptide target.

Ms Arokiadhas IswaryaImage Delegate ID Theme Details


Research


UniversityDesignation : Ph.D Scholar

: Immunostimulant is an alternative to the antibiotics to overcome the infectious disease witheffective growth and immune performance. The present attempt was made onto investigate the potentialof crustacean shell waste protein based zinc oxide nanoparticles (P-ZnO NPs) supplemented diet ongrowth, immune response and disease resistance of Oreochromis mossambicus. Shell protein wasextracted from the exoskeleton of Scylla serrate and P-ZnO NPs was synthesized and characterized. P-ZnO NPs was supplemented at concentration of 0.001%, 0.002% and 0.004% to a commercial diet, whichwas fed to triplicate groups of O. mosambicus for 30 days. Fishes received P-ZnO NPs expresssignificant increase in weight, growth and feed conversion ratio. During feeding trial, cellularimmune responses (myeloperoxidase activity, lysozyme activity and reactive oxygen activity) andhumoral immune responses (complement activity, antiprotease activity and alkaline phosphataseactivity) were checked at the interval of 15 days. After 30 days of post feeding, fishes werechallenged with aquatic fish pathogen A. hydrophila (1 × 107 cells ml-1) and the result ofchallenge study were observed with reduced mortality rate of fishes fed with P-ZnO NPs. Moreover,antibiofilm potential of P-ZnO NPs against Aeromonas hydrophila was visualized via confocal laserscanning microscopy (CLSM) reveals preformed biofilm thickness was significantly reduced to 11 µmat the concentration of 50 µg/ml than control. Thus from our observation, P-ZnO NPs supplementeddiet have a potential to strengthens the immune system of O. mossambicus.

Dr Dinesh KumarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : green life

siddhaDesignation : B.S.M.S

Corresponding Author: [email protected] Background: Drugs such as Siru peelai (Aerana Lanata)samoolam, Neermulli (Astera Canthalongi folia)samoolam, Nerunjil (Tribulus terrestris)samoolam, Mavilanga pattai (Crataeva religiosa) bark, and Vellari (Cucumis sativas) seeds used for the treatment and managing kidney stones. Objectives: the main objective of the study was drugs which are used to treat kidney stones are togethered and know the activity of the medicine Materials and methods: all parts of siru peelai, neermulli, nerunjil and bark of mavilangam and seeds of vellari all are dried without direct sun exposure then add equal weight of all ingredient mix and make it like kasayam. Then it is given to the patients by giving them 25 gm kasayam two times per day for 30 days and the result is compared. Kasayam (Decoction ) preparation: 400 ml water added with 25 gm kasayam and heated and reduced it to 100 ml then filtered and drinked morning and night with empty stomach.Results: the results were compared and analysed the siddha systems recommended drugs used for kidney stones. Conclusion: the drugs activity in the kidney stone is proved with patient report. References: 1.kunapadam mooligai 2. Pothu maruthuvam 3. Siddhar aruvai maruthuvam 4. Pathartha guna vilakkam

Dr VIKAS GUPTAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DAV College,

AmritsarDesignation : Assistant

Professor

Bronchial Asthma (Asthma) is a complex genetic disease characterized by coughing, breathlessness andcongestion in chest. IL-4 and TNF-? being pro-inflammatory cytokines have been strongly implicatedas the candidate genes in its pathophysiology. Studies have documented increased expression of IL-4and TNF-? protein in asthmatics as compare to normal controls. Of the various SNP’s, polymorphismat C-590T site in IL-4 and at G-308A site in TNF-? promoter gene has been associated with itsdifferential production, T allele being the high producer of IL-4 and A allele being the highproducer of TNF-? cytokine. Present study attempts to investigate promoter polymorphisms at C-590Tin IL-4 and G-308A in TNF-? gene for their association with Asthma. A total of 155 asthmaticpatients visiting TB and Chest Hospital, Amritsar and SGRD Institute of Medical Sciences andResearch, Amritsar and 211 normal healthy controls residing in Amritsar and adjoining areas weregenotyped for C-590T site in IL-4 using SSOP method and G-308A site in TNF-? using ARMS-PCRdeveloped in our laboratory. Statistically significant association was observed between asthmaticand IL-4 (-590 site) [Chi2=4.11 p value=0.04] and TNF-? (-308 site) [Chi2=5.79 p value= 0.016)]. Onfurther dividing asthmatics on the basis of pattern of disease, statistically significantassociation was observed between seasonal asthmatics vs control both in case of IL-4 [Chi2=9.55 pvalue=0.002] and TNF- ? [Chi2=5.34 p value= 0.020]. However, no association could be observedbetween perennial asthmatic vs controls in case of IL-4 (p value=0.654) and TNF- ? (p value=0.127).The present study strongly suggest an association between C-590T site in IL-4 and G-308A site inTNF-? promoter gene with susceptibility to asthma in Punjabi population.

Ms Sunanda BurmanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : The University

of BurdwanDesignation : Research

Scholar

Investigation of in-vitro antioxidant and antibacterial activity of methanolic extract of fruits of Combretum album Pers. Sunanda Burman1 and Goutam Chandra1* 1Mosquito, Microbiology and Nanotechnology Research Units, Parasitology Laboratory, Department of Zoology, The University of Burdwan, Burdwan-713104, West Bengal, India *E-mail: [email protected] . Abstract: Plants are reservoir for potentially useful phytochemicals and owing to the increasing occurrences of drug resistance to pathogenic bacteria there is a need to search and develop new phytochemicals in plant that can be used as economical source of antioxidant and antibacterial agents. This study has been designed to appraise the antioxidant and antibacterial activities of methanolic extract of fruits of Combretum album Pers. of medicinally important family Combretaceae. The antioxidant activity was determined by 2, 2-diphenyl-1-picrylhydrazyl radical scavenging assay and the antibacterial activity was evaluated by well diffusion method and determination of minimum inhibitory concentration. The maximum scavenging activity of methanolic extract of C. album fruits was observed at 87.4% with the IC50 value of 25??g/mL. and had antibacterial activity against both Gram positive and Gram negative bacteria. Higher inhibition zone was detected against E. coli (19.88?mm) with lowest MIC value (125µg/ml). Phytochemical screening showed presence of flavonoids, tannins, saponins and terpenoids in the methanolic extract and it can be concluded that these compounds may be responsible for antibacterial and antioxidant activity. FT-IR analysis detected various functional groups such as alcohols, amides, carboxylic acids, imides, hydrazines, ketones, amine, anhydride and azo groups. In conclusion, the results indicated that the methanolic extract of C. album fruits possessed strong antibacterial and antioxidant properties and could be an important source of natural compounds for development of new drugs. In order to fully explore the potential of this plant, in-vivo biological assessments of the extract and associated bioactive compounds are required to establish their pharmaceutical and pharmacognostic relevance.

Keywords: Combretum album fruit, methanolic extract, antioxidant, antibacterial, DPPH, FT-IR

References: 1. Perez, C.; Paul, M.; Bazerque, P. Antibiotic assay by agar-well diffusion method. Acta Biol. Med. Exp.erimenta.1990, 15, 113-115. 2. Kulisic, T.; Radonic, A.; Katalinic, V.; Milos, M. Use of different methods for testing antioxidative activity of oregano essential oil. Food Chem. 2004, 85,633–640.

Dr MUTHUSELVAM DImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bishop heber


Professor

In Drug development performed on computer in reference to biological experiments play a key role toexplore molecular aspect of targeting specific proteins through various software. It also synthesisthe bioactivities and inhibitory effects across mechanisms underlying for treatment of severalbacterial, fungal and viral diseases. Medicinal plants have been the single most constructive sourceof leads for the drug development thus played essential role in healing and preventing severaldisease. In the present studies, P.amboinicus was examined for their antibacterial activityparticularly against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa andEscherichia coli. In this analysis the phytocompounds were identified from GC- MS the compounds aredocked against OpenBable, Gold and PyMoL through molecular docking. The identified compoundsHexadecanoic acid, Palmytaldehyde, Dichloacetic acid, Safrole, 2-Cyclohexane-1-one and eugenol isbest bioactive compounds against colorectal cancer based on energy value.

Ms Manali DuttaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : The university

of BurdwanDesignation : J. R. F

Abstract: The indiscriminate use of chemical larvicidal and mosquitocidal agents in past decadeshave caused several hazardous effects to various lifeforms and led to development of increasedresistance among these vectors. Thus, arises the need for larvicides of botanical origin which aremore target specific and biodegradable. The present study showed the efficacy of the leaf extractsof Grangea maderaspatana against Aedes albopictus. According to standard protocol of WHO, larvalmortality was observed against all four larval instars of Ae. albopictus using five gradedconcentrations of crude (0.5% - 2.5%) and three different solvent [n-hexane, Chloroform : methanol(1:1 v/v), acetone] extracts (50 ppm – 250 ppm). Regression analysis showed Regression coefficient(R²) close to 1 in each case. Log-probit analyses were performed to determine the LC50 and LC90values. Diplonychus sp. was selected as the non-target organism which were exposed to LC50 values of3rd instar larvae and the results were examined after 72 h of exposure. 100% mortality was observedat 2% concentration of crude leaf extract and at 250ppm concentration of chloroform:methanol extractafter 72hr of exposure against 1st and 2nd instar larvae. LC50 and LC90 values forchloroform:methanol extract were 22.67 ppm and 39.46 ppm respectively for 1st instar larvae after 72h of post exposure. No adverse effect was observed in the non-target organism. Further biochemicalassays using the solvent extract claimed the presence of tannins, terpenoids, alkaloids, flavonoidsand glycosides in it. Hence, the bioactive fraction from G. maderaspatana can be used as a potentlarvicide against dengue vector Ae. albopictus.

Mr Santosh KumarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bihar Agricultural university,

Sabour, BiharDesignation : PhD scholar

Abstract: Remote Sensing is important tool for generating soil maps and helps to identify the area of specific textured soil in particular district. Present study conduct to signature capture of clay soils in Khagaria district of bihar. The Khagaria district is situated north of river Ganga. The whole tract of Khagaria district was flat alluvial plains abounds in marshy and swampy land. Clear patches found in visual interpretation of satellite image from surrounding were observed in blue tone of the converted RGB image. The most of clay soil area found in maximum coverage of clay soils was observed in Khgaria (12.79%) followed by Maheshkhunt (11.12%), Mansi (10.48%), Gogri (10.46%) and Pasraha (9.90%) blocks. However, in context of physicochemical status of soils, the clay content varied from 57 to 66%, soil pH (6.56-7.64), EC low to medium, available nitrogen low, available phosphate medium and available potash high were calculated. Research findings may be helpful for the confirmation of heavy texture soils under low land topography of Bihar. key words: Remote sensing, Clay, Topography

Ms SUBIAH HELAL ARZOOImage Delegate ID Theme Details


Research


UniversityDesignation : Ph. D. Scholar

Background: Diabetes mellitus the fastest growing metabolic disorder, with nearly 98 million Indians affected, is mainly caused by insufficient or insensitivity of insulin which alters metabolism and function of organs. Synthetic drugs and insulin therapy against diabetes possess numerous drawbacks. Diabetic people are advised to choose low-glycaemic food and herbal products to manage diabetes. The low glycaemic pumpkin seed is easily available in the Indian subcontinent and Gymnadenia Orchidis Lindl plant is found in the Himalayan terrain at 2400-4000 m. This study has proved the synergistically improved efficacy of Gymnadenia orchidis root Salep and pumpkin seed against Type 2 diabetes associated complications on adult female mice.

Aim: This study was designed to determine the combined efficacy of Gymnadenia Orchidis Lindl, a Himalayan origin herbal root Salep and the low glycemic indexed pumpkin seed in the management of diabetes and its related complication in diabetic induced adult female mice.

Method: Animals were divided into 6 groups of which 2 groups were taken as Normal Control and Food Control. Rest 4 groups were made diabetic by Streptozotocin, of which one group was kept as Diabetic Control, and the other three groups were supplemented with effective dose of root Salep (200 mg/kg of body weight), pumpkin seed (5%) mixed food and root Salep and pumpkin seed both respectively. Changes in the hematological, biochemical and antioxidant parameters were observed after 21 days of treatment. Data were analyzed by ANOVA for statistical significance.

Results: The diabetic mice showed a significant (p Conclusion: It can be said that the combined usage of the root Salep and the pumpkin seed helped to ameliorate the problems significantly in comparison to the natural products being used individually. The known antioxidants (tocopherols and phytosterols) present in the pumpkin seed along with the Terpenoids present in the root Salep could have been the major reason behind the ameliorating effects against diabetic induced complications. Efficacy of this product and combination needs to be checked on a large diabetic population for stronger evidence.

Dr Jitendra AcharyaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Government

medical collegeDesignation : Senior

demonstrator

BACKGROUND PERSONS OF THE END OF LIFE REQUIRE SPECIAL ATTENTION TO THEIR RAPIDLY FAILING ORAL HEALTH. 89 PERCENT OF THOSE TERMINALLY ILL WITH CANCER WILL COMPLAIN OF AT LEAST ONE ORAL SYMPTOM. ORAL CARE IS A VERY IMPORTANT PART AS A TREATMENT ASPECT OF PALLIATIVE CARE DEPARTMENT. AS WE ALL KNOW DURING END STAGE OF LIFE WHILE PATIENT GO THROUGH ALL KIND OF RADIOTHERAPY CHEMOTHERAPY TREATMENT GRADUALLY PATIENTS IMMUNITY WILL BE COMPROMISE. MOST COMMON ORAL PROBLEM IS CANDIDIASIS THRUSH DIFFERENT TREATMENTS HAVE BEEN USED IN APPLICATION TO SYMPTOMATIC ORAL CANDIDIASIS WITH VARIABLE RESULTS PERHAPS CAUSED BY THE REFRACTORY NATURE OF THE DISEASE. THE OBJECTIVE OF THIS STUDY WAS TO EVALUATE THE EFFICACY OF THE TOPICAL APPLICATION OF ALOE VERA IN ORAL CANDIDIASIS COMPARED WITH PLACEBO.? METHODS A TOTAL OF 40 PATIENTS OF PALLIATIVE DEPARTMENT WITH ORAL CANDIDIASIS WERE RANDOMIZED IN A DOUBLE BLIND STUDY TO EITHER AV 20 PATIENTS OR PLACEBO 20 PATIENTS, AT A DOSE OF 400 MICRO LITER 70 PERCENT CONCENTRATION THREE TIMES A DAY AT PALLIATIVE CARE DEPARTMENT OF SARDAR PATEL MEDICAL COLLEGE BIKANER RAJASTHAN. A VISUAL ANALOG SCALE WAS USED FOR RATING MUCOSAL LESIONS AND PAIN WITH THE APPLICATION OF A CLINICAL SCALE FOR SCORING THE LESIONS THE ORAL HEALTH IMPACT PROFILE 49.THE PATIENTS WERE EVALUATED AFTER 2 AND 4 WEEKS. RESULTS DATA ANALYSIS STUDY GROUPS THAT HAD BEEN GIVEN ALOE VERA BY STATICALLY ANALYSIS THERE WAS A STATISTICALLY SIGNIFICANT DIFFERENCE MUCOSAL LESION AND ORAL DISCOMFORT AS GRADED BY VISUAL ANALOGUE SCALE. CONCLUSION WITHIN THE LIMITATIONS OF THIS STUDY ALOE VERA IS EFFECTIVE AS A TOPICAL ANTIFUNGAL AGENT. THE TOPICAL APPLICATION OF ALOE VERA IMPROVES THE TOTAL QUALITY OF LIFE SCORE IN PATIENTS WITH ORAL CANDIDIASIS.

Dr FARHEEN WAZIRIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : G B M

COLLEGEDesignation : Assistant

professor

Abstract: Aging population, stressfully transforming lifestyle and perturbed urological physiology has contributed to the recent anxious rise of incidence of prostate cancer (PCa) across the globe, including India. Despite of advancing knowledge in both medical diagnostic technology and curative interventions; and decades of applied urological research, the existing insights are insufficient to curb the menace. This very situation intrigued us to investigate and identify the differential and clinically relevant prognostic serum based biomarkers in induced animal model of PCa with an intention to contribute an insight in early and accurate detection and additive avenues for effective clinical case management. Recently, proteomic approaches have been employed to identify markers for the diagnosis of cancer at an early stage with noteworthy results. To extend these studies, we utilized the serum proteomics for identification of differentially expressed proteins in its early stage using two – dimensional polyacrylamide gel electrophoresis (2-DE) followed by peptide mass fingerprinting based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) in prostate cancer Wistar rat model developed as a result of N-nitroso, N-methyl Urea (MNU) administration. The significance of our study lies in reporting two novel serum proteins –ZFP663 and RASA3 – found to be differentially expressed during the early stages of tumorigenesis in treated animals compared to control subjects with their subsequent validation by qRT-PCR. Combining well-defined animal model with proteome analysis to identify potential serum protein markers would improve our understanding of the fundamental changes that contribute to the process of development and progression of this malignancy as well as in providing a potential candidature in improving PCa diagnosis during its early stage. In conclusion, these proteins may therefore possess a potential candidature in improving PCa diagnosis during its early stage.

Mr SASWAT KUMAR MOHANTYImage Delegate ID Theme Details


Research


PONDICHERRY UNIVERSITYDesignation : Ph.D. sCHOLAR

Insulin like growth factor -1 (IGF-1) is a key factor for growth and fuel metabolism and areassociated paradoxically with cancer risk and in giving protection from numerous age-relateddiseases like cardiovascular disease, type 2 diabetes and osteoporosis. Thus, the relevance of IGF-1in regulating energy status in different age and gender groups remain unclear. To this end, weperformed a study by targeting this signaling pathway through specific inhibition of its receptor(IGF-1R) in both young (1-month) and old (21-month) male and female Wistar rats by cyclolignanpicropodophyllin (PPP). Our findings showed that on inhibition, serum glucose level increasedsignificantly irrespective of age and gender, and this increase is maximally observed in old femalerats. Western blot analysis confirmed the inhibition of downstream signaling of IGF-1 withsubsequent down-regulation of PI3K/Akt pathway that is also maximally observed in old femaleanimals. Furthermore, our study on the mRNA expression profiles of important glycolytic andgluconeogenesis enzymes revealed that on blocking of IGF-1 signaling, expressions of Glucokinase(GK) and Hexokinase (HK) declined significantly by 0.4-0.7-fold in both the sexes. On the contrary,there were increased expressions of Phosphoenolpyruvate carboxykinase (PEPCK), Glucose 6-phosphatase(G6PASE), and Pyruvate dehydrogenase lipoamide kinase isozyme 4 (PDK4). More interestingly, in acomparison between the genders, we found that there were lesser expressions of cytoplasmicgluconeogenic enzymes (PEPCK and G6PASE) and higher expression of the mitochondrial gluconeogenicenzyme (PDK4) in males in comparison to females. Lastly, this shift from glycolysis togluconeogenesis is ultimately sensed with enhanced phosphorylation of AMPK? observed. Overall, thisstudy highlighted the significance of IGF-1 signaling in regulations of the different liver energyand important signaling pathways and these regulations are dictated in an age- and gender-specificmanner.

Dr Mamoni DashImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Institute of Life

Sciences, ILSDesignation : Ramalingaswami

Fellow

The healing of large bone defects caused by major trauma, infection, prosthetic revision, bonetumors resection or non-healing fractures still remains a therapeutic challenge. Currently, the mostprevalent treatment includes autologous bone grafting which presents certain shortcomings. In orderto overcome the shortcomings of certain existing methods tissue engineering has been helpful inoffering solutions. However, still a lot of issues related to immune-rejection and concomitant bonegrowth in such scaffolds needs to be addressed. We work towards designing tissue engineered bonegrafts and understanding in-vitro mineralization on them. Our focus lies on protein based substratesand their development as in-vitro models to study and understand mineralization. In view of this,protein-based scaffolds are developed using a combination of crosslinking approaches. Fundamentalaspects, such as the porosity, pore size and pore shape, as these will affect the scaffoldspermeability/diffusivity, degradation rate and elastic modulus are taken into consideration andoptimized while designing the protein based in-vitro model. The cell-material interaction and thebiological processes necessary for regeneration are monitored with positive results on cellviability, proliferation and mineralization on the prepared protein scaffolds.

Ms Shubhaisi DasImage Delegate ID Theme Details


Research



Scholar

Study of antibacterial activity of Cardamine hirsuta extracts against human and fish pathogenic bacteria Shubhaisi Das 1*and Goutam Chandra1 1Mosquito, Microbiology and Nanotechnology Research Units, Parasitology Laboratory, Department of Zoology, The University of Burdwan, Burdwan-713104, West Bengal, India E-mail:[email protected]

In recent time ‘Herbal’ is treated as natural health solution and regained its popularity because chemically synthesized antibiotics become resistance against infectious disease caused by bacteria. Present investigation was conducted to evaluation of antibacterial activity as well as to study the possible bioactive compound present in Cardamine hirsuta extracts. Plants were collected outskirts of Burdwan and shed dried for 15 days. After 15 days extracts were prepared using soxhlet apparatus. Antibacterial activity of various solvent extracts of C. hirsuta was tested in laboratory condition against four human pathogenic bacteria namely Escherichia coli (MTCC 739), Pseudomonas aeruginosa (MTCC 2453), Bacillus subtilis (MTCC 441), Staphylococcus aureus (MTCC 2940) and four fish pathogenic bacteria namely B. licheniformis (MTCC 530), B. mycoides (MTCC 7343), P. fluorescens (MTCC 103) and P. putida (MTCC 1654) by agar well diffusion method. Methanol extracts were showed most excellent inhibitory activity against all the tested isolate with compared to other solvent extracts. Chloramphenicol (30 µg/disc) Amoxicilin(30µg/disc) and Kanamycin (30µg/disc ) were used as positive control. Minimum inhibitory concentration (MIC) for all the tested bacteria was done using standard procedure. Phytochemical analysis of methanol extracts confirmed the presence of saponins, cardiac glycoside, alkaloids and flavonoids. Fourier Transform Infra Red analysis revealed presence of various functional groups. From the above experiment it can be concluded that methanol extracts of C. hirsuta contains various phytochemical groups which may acts as antibacterial compound in future.

Dr Nabanita GhoshImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Maulana Azad


Professor

Transient Short-term memory loss in mouse model of acute Parkinsonism Nabanita Ghosh1 and Arindam Bhattacharyya2* 1Department of Zoology, Maulana Azad College, 8, Rafi Ahmed Kidwai Road, Kolkata-700013 2Department of Zoology, University of Calcutta, 35, Ballygunge Circ. Road, Kolkata- 700019 e-mail: [email protected]

Abstract: Parkinson’s Disease (PD), one of the most commonly occurring age-related progressive neurodegenerative disorder, is characterized by dopaminergic (DA) neurodegeneration in substantia nigra (SN) pars compacta and dopamine depletion in striatum, cytoplasmic inclusions of aggregated proteins [Lewy bodies (LBs)], and chronic neuroinflammation (McGeer & McGeer, 2008). The motor symptoms observed in PD include rigidity, bradykinesia, tremor and postural instability (Postuma et al., 2015). Cognitive impairments associated with PD are mainly related to the executive functions, deficits in attention, planning, concept formation, and working memory. Memory deterioration affects working memory domains and object recognition which is also frequently reported as one of the earliest symptoms in PD patients (Solari et al., 2013). In the present study, we investigated the status of short term memory (STM) upon establishment of acute Parkinsonism in mouse and also the status of glutamate neurotransmitter system in the hippocampus (brain region responsible for memory formation). Methods include Novel object recognition test, ELISA, Western blotting, real-time PCR. It was found that within a span of seven days of our study regime, the STM drastically reduced initially on day 1 up to day 3. However, it automatically recovered on day 7. This study also revealed that the glutamate homeostasis in the hippocampus got altered during the memory impairment phase. So, based on these findings, it can be concluded that the transient memory loss in acute Parkinsonism is an outcome of impaired glutamate signaling in the hippocampal region of the mouse brain.

References: 1. McGeer, P. L.; & McGeer, E. G. Movement disorders: official journal of the Movement Disorder Society. 2014, 23(4), 474–483. 2. Postuma, R. B.; Berg, D.; et al. Movement disorders: official journal of the Movement Disorder Society. 2015, 30(12), 1591–1601. 3. Solari, N.; Bonito-Oliva, A.; Fisone, G.; & Brambilla, R. Understanding cognitive deficits in Parkinson’s disease: lessons from preclinical animal models. Learning & memory (Cold Spring Harbor, N.Y.) 2013, 20(10), 592–600.

Mr Kunal PalImage Delegate ID Theme Details


Research



Research Fellow

Implications of different approaches to deliver curcumin for triple negative breast cancer therapy in invitro and invivo model Kunal Pal1,2*, Ishita Saha, Dipranjan Laha, Parimal Karmakar Contact author affiliation and email 1 Department of Life Science and Biotechnology, Jadavpur University, Kolkata-700032, India. 2Division of Molecular Medicine, Bose Institute, Kolkata 700054, India. [email protected] Other authors’ [email protected],[email protected],[email protected]

Contact author [email protected]

Among the different sub-type of breast cancer, triple negative breast cancer (TNBC) refers to the most aggressive breast cancer phenotype where ER (Estrogen receptor), PR (Progesterone receptor) and HER2 (human epidermalgrowth factor receptor 2) are not expressed. No such effective treatment has been implemented successfully for metastatic TNBC following surgery, radiation and chemotherapy.Curcumin has shown promising therapeutic activity against triple negative breast cancer cell (TNBC), but it shows low efficacy and low bioavailability when administered as a free drug hindering its therapeutic applications. We have developed athree pronged approach involving the development of three different drug delivery systems which includes the isoreticular nanoscale metal organic frameworks (IRMOF) nanoparticles[1], biopolymeric microspheres synthesized from natural excipients Gum acacia (GA) [2] and polymeric microvehicles synthesized from PLGA which is a biodegradable copolymer[3]. The salient features of our drug carriers include prolonged circulation time, increased tumor localization,controlled deliveryof the therapeutics.We have used biocompatible drug delivery systems where curcumin can be loaded comfortably by co-precipitation method and thereby increases its bioavailability. The curcumin encapsulated drug carriers were found to induce apoptosis in TNBC cells by perturbing the mitochondrial membrane potential. Folic acid was conjugated to curcumin encapsulated biocompatible drug delivery systems, for delivering it specifically to the cancer cells since the folate receptors are overexpressed in the TNBC cells. The in-vivo study in BALB/C mice model exhibited encouraging tumor regression. Our results vividly implicates that these drug carrier systems can be deployed as effective vehicle for the delivery of different anticancer drugs particularly which are hydrophobic in nature to the various folate receptor overexpressing cancer cells circumventing any adverse effects on the normal cells. References [1] Laha,D.; Pal,K.; Ray Chowdhuri,A.; Parida, P.K.; Sahu,S.K.; Jana,K.; Karmakar,P. New J. Chem. 2019,43, 217-229. [2] Pal,K.; Roy S.; Parida P.K., Dutta, A.; Souravi Bardhan,S.; Das,S.; Jana,K.; Karmakar,P.; Mater. Sci. Eng. C. 2019, 95, 204–216. [3]Pal K.;Laha D.; Parida P.K.; Roy,S.; Bardhan,S.; Dutta,A.;Jana,K.;Karmakar,P.; J. Nanosci. Nanotechnol. 2019, 19(7),3720-3733.

Mr Rohan GuptaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-NEERI

Designation : JRF

Anaerobic treatment is considered to be one of the most economical methods of wastewater treatment amongst the biological solutions. However, in case of low strength wastewaters like domestic sewage (DS), anaerobic treatment does not often generate useful quantities of biogas. The reason being temperature. Low temperatures, in association with low strength of wastewater makes adaptation of biomass for methanation of domestic sewage a problem. These problems are of serious concern at regions atmospheric temperature is The present study focuses on faster adaptation of moderate-temperature methanogenic (MTM) biomass at psychrophilic conditions (10-20OC). Often acclimatization of methanogenic biomass at temperatures In the start-up phase of CSTR, the operating temperature of the reactor was progressively reduced from 25°C to 15OC in a step-wise manner. Within 2 months, the reactor operated at 1.5d HRT adapted to low temperature methanogenesis with >80% removal of COD. Methane concentration in biogas ranged from 50-70% (v/v) due to increase in number of hydrogenotrophic methanogens. The present study thus demonstrates an effective method for quick adaptation of PAM biomass from MTM biomass for efficient treatment of DS at lower mesophilic to psychrophilic temperatures. The method has potential applications in sewage treatment plants operating in colder climates in Northern belts of India as well as in western countries.

Dr Ashok SharmaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : All India

Institute of Medical Sciences, New Delhi


CANCER EPIGENETICS: NEW MECHANISM AND NEW THERAPY for CANCER

AIIMS, New Delhi

Abstract: With the control of communicable diseases, we in India are facing gradual increase in the incidence of non communicable diseases including cancer. The incidence of cancer in India is 1.5 million and 4.5 million are living with it. This is expected to rise to 1.73 million cases and 0.88 million deaths in 2020. Cancer related morbidity and mortality is very high in view of presentation at advanced stages. However, about 60% of India centric cancers are preventable. Hence, in a lower middle income country like ours, prevention & early detection are important ways to control cancer. Assertive discoveries have been carried out during the past decade to explore the role of epigenetic mechanisms for the regulation of cellular phenotype. This regulation provides the software that packages DNA, modifications in gene expression without changing the DNA sequence of a gene. These are called epigenetic alterations. These alterations include methylation, acetylation, phosphorylation and ubiquitylation of DNA and histone proteins (nucleosomes) as well as chromatin remodelling. “Epigenetics” refers to heritable changes in gene expression patterns without changing the primary DNA sequence. Our lab basically focuses on cancer epigenetics and we are trying to decipher the epigenome regulation that may lead to development of new epigenetic therapeutic drugs. The recent discovery of Cancer Testis/Germline (CT/CG) antigen expression in cancer suggests a strong link between gametogenesis and carcinogenesis.CG antigens have the potential to serve as biomarkers for cancer stem cells and potential targets in cancer metastatic processes as well as in the recurrence of cancer after chemotherapy. We are indulging to open the new avenues for novel Cancer Testis/Germline (CT/CG) POTE antigens to be used for cancer immunotherapy for treating gynaecological cancer patients for better reproductive health. POTE (Prostate, Placenta, Ovary, and Testis-expressed) is a recently discovered gene family consisting of 14 autosomal and pericentromeric localized cancer-testis/germline antigen genes. The POTE paralogs gene family encodes proteins with cysteine-rich (CRR) domains, ankyrin repeat motifs and ?-helical regions. It is established that epigenetic mechanisms control expression of CT/CG antigens. Epigenetic modulatory agents robustly promote expression of CG antigens, as well as the class-1 histocompatibility complex (MHCI). Thus, we emphasize the possible clinical use of epigenetic modulators to augment the immunotherapeutic potential of POTE family antigens, and how this will ultimately improve strategies for cancer detection and treatment.

Mr Ajit Kumar SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : institute of life

sciencesDesignation : Senior

Research Fellow

The FK506-binding protein (FKBP) family of peptidyl-prolyl isomerases (PPIases) are ubiquitouslypresent in all life forms and is characterized by a common catalytic domain that binds to theinhibitors FK506 and rapamycin. One of the seven multi-domain FKBPs within the Arabidopsis thaliana,the nuclear-localized AtFKBP53 has a conserved FK506-binding domain and a highly charged domain inthe N-terminus. AtFKBP53 has been reported to be a histone chaperone and that the N-terminal acidicdomain is sufficient for the chaperone activity. To better understand the molecular details, wedetermined the crystal structure of AtFKBP53 domains, revealing the protein to have an N-terminalnucleoplasmin domain and a C-terminal FK506-binding domain. This study reports the first in-depthcharacterization of a plant nucleoplasmin. Overall, AtFKBP53 turns out to be a chimeric chaperonewith functional nucleoplasmin and PPIase domains. Here we present the results from structural,biophysical and functional characterization of AtFKBP53.

Ms Debbethi BeraImage Delegate ID Theme Details


Research



Fellow

Functionalised biomimetic Hydroxyapatite NPs as a smart material against pathogenic multidrug-resistant bacteria Debbethi Bera1,2*, Kunal Pal, Parimal Karmakar, Papiya Nandy, Sukhen Das

Contact author affiliation and email 1Department of Physics, Jadavpur University, Kolkata-700032, India. 2 Centre for Interdisciplinary Research and Education, 404B, Jodhpur Park, Kolkata-700068, India. [email protected]

Other authors’ email- [email protected],[email protected],[email protected],[email protected] Contact author email- [email protected]

The persistent dissemination of resistant bacterial strains is a grave contemporary global impediment in hospital-acquired infections which needs to be mitigated with immediate effect[1]. In particular, infections from pathogenic multidrug-resistant (MDR) Gram positive bacteria (like Enterococcus faecalis) which are resistant to conventional antibiotic therapy are attracting immediate global attention. Here we report the synthesis of nanoscale hydroxyapatites (HAPs), which is a well known biomimetic ceramic material having needled shaped morphologies. We have encapsulated Vancomycin (VAN) within these nanoparticles and have conjugated the targeting ligand (folic acid) by a facile synthesis process in order to enhance the therapeutic efficacy against MDR E. faecalis. These functionalized HAPs are thoroughly characterized by employing field emission scanning electron microscopy (FESEM), Powder X-ray diffraction (PXRD), ulltraviolet–visible spectroscopy (UV-Vis) and dynamic light-scattering (DLS) techniques. Our results suggest that these functionalized HAPs transport could successfully transport Vancomycin across the cell wall of MDR E. faecalis through endocytosis. The determination of selective antibacterial activity has been envisaged with the help of extensive e in-vitro assays like the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and generation of reactive oxygen species (ROS).This study vividly establishes that these folic acid conjugated HAPs are promising antibacterial agents against MDR E. faecalis and related pathogenic resistant bacterial strains. Reference- [1]Li X.; Robinson S.M.; Gupta A.; Saha K.; Jiang Z.; Moyano D.F.; Sahar A.; Riley M.A.; Rotello V.M . ACS Nano.2014 , 8, 10682–10686.

Ms Lajpreet KaurImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : INMAS,DRDO

Designation : JRF

Abstract: Hydrogel formulation containing EP was developed as a wound healant because of itsanti-inflammatory properties. In order to establish its role as a wound healant repeated dose dermaldrug toxicity study was performed according to the OECD guideline 410. Adult Sprague Dawley ratswere used for dermal toxicity study wherein the topical hydrogel containing 2 % of EP was applied todorsal surface for 21 days. The body weight and food consumption were continuously observed. Thebiochemical, hematological and histopathological analysis was performed after 21 days. There was nochange in food consumption and body weight during the period of application of the hydrogel. All theparameter including biochemical and hematological were within their physiological reference range.Histology and SEM analysis of formulation treated skin revealed normal skin physiology. According toOECD guideline 410 hydrogel with 2% EP was found to be safe and can be used as a wound healant.

Ms asma thaseenImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : university of

lucknowDesignation : research

scholar

Liposome Nanoparticle Carrier for the Treatment of Cancer Asma Thaseen and M. Serajuddin Fish Biology Lab Department of Zoology, lucknow University, Lucknow-226007, U.P., India Email: [email protected] [email protected]

Background Liposome was first described in mid 60s as a tool for physical and life sciences, and now modified form or ‘second -generation liposomes’ is being used in the area of health science for delivering the various types of drugs (Sadabady et al., 2013). Problem: The chemically synthesized drugs of chemo and radiation therapy in the treatment of cancer posses various side effects on patient health, and amount of the drug reached to the targeted site is significantly low as compared to the original dose. Efforts are being made to find out the alternatives to overcome the drawbacks. Method used: Reverse phase evaporation (Dua et al., 2012) method is widely used for the preparation of liposome because it provides high aqueous space-lipid ratio and capacity to trap large number of drug molecules in the liposome vesicle. Significance: The anti-neoplastic and anti-cancerous activity had been studied on colo-rectal cancer by loading omega 3-PUFA in resveratrol drug encapsulated in solid-lipid nanoparticle(Serini et al., 2018). The foremost importance of liposome is to reduce the toxicities and enhance the efficiency by delivering the pure form of drug in target organ. The paper deals with the status, merits and demerits of the use of the fish polyunsaturated fatty acids (eicosapentaenoic acid and docosahexanoic acid) liposome in in-vitro treatment of lung and oral cancers in human beings because the fish PUFA has been reported as a potent agent who induces apoptosis and anti-proliferation in various cancers. Conclusion: The mortality rate due to cancer is very high in comparison to other disease due to side-effects of chemo and radiation therapy. Liposome targeted nano-form drug of fish PUFA can provide better treatment by targeting the cancer tissues and not affecting the other healthy normal tissue. References: 1. Sadabady, RR.; Zarghami, N.; Hanifehpour, y.; Samiei, M. Liposome: classification, prepration, and applications. Nanoscale research letter.2013, 8:102, 1556-2768. 2. Serini, S.; Calviello, G.; Cassano, R,: et al. Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro. Intl journal of molecular science.2018, 19, 586. 3. Dua, JS.; Rana, AC.; Bhandari, AK. Liposome: methods of preparation and applications. Intl journal of pharmaceutical studies and research.2012, 3:2, 14-21.

Mr SUDHAKAR PADMESHImage Delegate ID Theme Details


Research


University Uttar PradeshDesignation : PhD Scholar

Identification and characterization of bacteriophage against five different multi drug resistant strains of Staphylococcus aurious Sudhakar Padmesh1, Manodeep Sen2 & Aditi Singh1* 1Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Gomti Nagar Extension, Lucknow. AIB Communication No. AIB/RA/2019/299 2Dept. of Microbiology, Ram Manohar Lohia Institute of Medical Sciences, Gomti Nagar, Lucknow.

*Corresponding Author: [email protected] Staphylococcus aureus is an opportunistic pathogen with a capacity to develop antibiotic resistance easily. This underlies a larger proportion of hospital-acquired infection and higher morbidity and mortality, compared to other bacterial infections. Effective novel approaches for treatment of infections induced by this pathogen are therefore necessary. Phage therapy represents a promising alternative solution to eradicate antibiotic- resistant pathogens. Here we investigated phage efficacy against five (4 clinical and one ATCC) multi drug resistant(MDR) Staphylococcus aureus. High biodiversity of the collection is indicated by its characteristics, i.e: biological characteristics i.e: host range, plaque size and morphology, growth at various temperature, thermal inactivation, sensitivity to low and high pH, sensitivity to osmotic stress, survivability upon treatment with organic solvents and detergents. By the end of the research no longer collection of phage from a single environmental source investigated by these means had been found. Moreover, particular bacteriophage revealed unusual biological features, like ability to form plaques at low temperature (4 ?), resist high temperature(62? or 95? ) or survive in the presence of an organic solvents (ethanol, acetone, DMSO, chloroform) or detergent (SDS, CTAB) making them potentially interesting in the context of biotechnological applications like phage therapy. These strains later will be sent for the sequencing and TEM analysis. Keywords: Bacteriophage, MDR, TEM, SDS, Staphylococcus aureus

Reference: • Goode D, Allen VM, Barrow PA. Reduction of experimental Salmonella and Campylobacter contamination of chicken skin by application of lytic bacteriophages. Appl Environ Microbiol.2003;69:5032–5036. • Wagenaar JA, Van Bergen MA, Mueller MA, Wassenaar TM, Carlton RM. Phage therapy reduces Campylobacter jejuni colonization in broilers. Vet Microbiol. 2005;109:275–283. • Amit Singh et al. Recent Advances in Bacteriophage Based Biosensors for Food-Borne Pathogen Detection. Sensors 2013, 13(2), 1763 1786; doi:10.3390/s130201763 • https://www.cdc.gov/drugresistance/index.html • D.E.Bfudley et al.(1965) The Isolation and morphology of Some New Bacteriophages Specific for Bacillus and Acetobacter species. J. gen. Mi~robiol. (1965), 41, 233-24. • Hirsh DC, Martin LD (1983) Appl Environ Microbiol 45(1):260–264 • Hirsh DC, Martin LD (1983) Appl Environ Microbiol 46(5):124Microbial.

Ms Diksha AroraImage Delegate ID Theme Details


Research


science college,MLSUDesignation : student

Electronic nose (e-nose) technology was developed in order to mimic human olfaction which can detect the odour of various compound and gases as it combines the pattern recognition or non – specific gas sensors to analyze and characterize the odour without separating the mixture into individual components. The increasing environmental pollution due to release of toxic effluents from industries is polluting water bodies at an alarming high rate. Hitherto other techniques such as GC/MS, PCR, spectrophotometer were used to divulge these pollutants or chemicals, which are time consuming. Whereas e-nose is highly sensitive, rapid responsive with a wide sensing range. The e-nose technology have a plethora of importance in fields such as agriculture, forestry, disease diagnostic, environmental monitoring, waste management etc. The e-nose finds it’s application in the early diagnosis of a disease by detecting volatile organic compound released by plants in surrounding and thereby take preventive measures to decrease the morbidity rate in plants. For pollutant peak levels like sulphur dioxide and nitrogen dioxide, Environmental Protection Agency (EPA) is working to determine where and how often unhealthy peaks occur. To detect these peaks, e-nose may prove very beneficial and effective in preventing their emission. Our focus is to develop a nanoparticle (NP) containing biosensor array for sensing SO2, NO2 and new pollutants and contaminants in plants and environment as well as the detection of several volatile organic compounds released by plants. Gold (Au) NPs can be useful for identification and generation of volatile fingerprints. Using this a sensor array can be programmed to identify the potent pollutants in environment and VOCs in plants disease.

Mr tushar ivnatiImage Delegate ID Theme Details


Research


science collage,MLSUDesignation : student

Electronic nose (e-nose) technology was developed in order to mimic human olfaction which can detect the odour of various compound and gases as it combines the pattern recognition or non – specific gas sensors to analyze and characterize the odour without separating the mixture into individual components. The increasing environmental pollution due to release of toxic effluents from industries is polluting water bodies at an alarming high rate. Hitherto other techniques such as GC/MS, PCR, spectrophotometer were used to divulge these pollutants or chemicals, which are time consuming. Whereas e-nose is highly sensitive, rapid responsive with a wide sensing range. The e-nose technology have a plethora of importance in fields such as agriculture, forestry, disease diagnostic, environmental monitoring, waste management etc. The e-nose finds it’s application in the early diagnosis of a disease by detecting volatile organic compound released by plants in surrounding and thereby take preventive measures to decrease the morbidity rate in plants. For pollutant peak levels like sulphur dioxide and nitrogen dioxide, Environmental Protection Agency (EPA) is working to determine where and how often unhealthy peaks occur. To detect these peaks, e-nose may prove very beneficial and effective in preventing their emission. Our focus is to develop a nanoparticle (NP) containing biosensor array for sensing SO2, NO2 and new pollutants and contaminants in plants and environment as well as the detection of several volatile organic compounds released by plants. Gold (Au) NPs can be useful for identification and generation of volatile fingerprints. Using this a sensor array can be programmed to identify the potent pollutants in environment and VOCs in plants disease.

Mr Mohammad VikasImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : BGSB

University, RajouriDesignation : Research

Scholar

Saffron is a perennial, triploid and sterile plant, propagated vegetatively & majorly grown in blacksoils. As in India, Saffron cultivation is mainly confined to Kashmir region with an estimatedproduction of tonnes adding to the state's economy in crores. But from past few years the productionis dwindling because of the disease occurrence at corm stages (vegetative part of saffron) like CormRot Disease, decreasing the overall production and the quality. Therefore a minor study wasconducted to produce Disease free Corms under invitro conditions through Plant Tissue CultureTechniques and the objective was met out successfully. The challenges faced by the farmers is thedeteriorating pH of soil, lack of irrigation and lack of awareness to new technologies and services.

Mr K VIGNESHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Anna

University ChennaiDesignation : Doctoral

Research Scholar

Association of sequence variants in the regulatory region of HLA-G (3’UTR region) with vertical HIV Transmission

Vignesh Karthikeyan1#, Sivaramakrishnan2, Swati Ahir Bist3, Jayanthi Mania Pramanik3

1Centre for Biotechnology, Anna University, Chennai-600025 2Departmennt of Biotechnology & Genetic Engineering, Bharathidasan University, Tiruchirappalli-600024 3Department of Infectious Diseases Biology, National Institute for Research in Reproductive Health (NIRRH), Indian Council for Medical Research (ICMR), Mumbai-400012. E.mail: [email protected]

HLA-G gene is a non-classical MHC class 1 molecule that is highly expressed in the trophoblast at the maternal-fetal interface and is thought to play a crucial role in ensuring a successful pregnancy. HLA plays a significant role in the immune response particularly in antiviral immunity. This study investigated the association of sequence variants in the regulatory region of HLA-G (3’UTR region) with vertical HIV transmission in our respective study groups. Thirty mother-child pairs (60 samples) were taken for our study, which included 20 pairs of HIV exposed uninfected children and their seropositive mothers and 10 pairs of HIV infected children and their seropositive mothers. The genomic DNA obtained from the blood samples after DNA extraction were quantified by UV-nano spectrophotometer followed by ?-globin gene PCR and HLA-G PCR for 8-3'UTR region. After performing the DNA Sequencing, the results were analyzed using nucleotide-nucleotide BLAST searches. To assess the differences in gene frequencies in each of the HLA-G variant of studied exon among HIV-1 non-transmitting and transmitting mother-child pairs, Fisher' exact test was applied with corresponding two-sided p-values, odds ratio (OR) and 95% confidence intervals (CIs). HLA-G DNA sequence variants between HIV non-transmitting and transmitting mother-child pairs for the 3’UTR region was compared using the Clustal omega software available at EMBL-EBI website. There was no difference in the frequencies of the HLA-G 14bp indel polymorphism in both the groups. No sequence variation was observed between children and their respective mothers. The HLA-G 14bp indel polymorphism in 3’UTR region shows very less polymorphism and it is not found to be associated with vertical HIV transmission.

Dr PRIYANAKA BABELImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Mohanlal

Sukhadia University Designation : Teaching

Consultant

Application of Nano-Biotechnology in Medicinal and Aromatic Plants (MAPs) Tissue Culture Technology for Sustainability in Southern Rajasthan

Rajesh Kumar Dubey, Director, NRC Biotechnology, MLS University, Udaipur, Rajasthan Priyanka Babel, Faculty, Department of Biotechnology, MLS University, Udaipur, Rajasthan E-mail: [email protected], [email protected]

Forests are the lungs of nature and one of the most valuable ecosystems, in the world. As the population increases, the exploitation of natural resources is exponentially increasing. This is alarming and may lead to severe consequences, detrimental to nature of .In order to regenerate lungs of nature the science of Nano-biotechnology and modern tools may prove to be the most important asset in the 21st century. Totipotential application of plant cell, tissue and organ culture has proven its potentials for the emergent application in the improvement of important and threatened medicinal plants and their sustainability. Biodiversity of Rajasthan is much challenged and related with Aravalli hills which encompass medicinal plants growing in this region. The tribals of the region are living in very close vicinity of natural diversity and over the ages they have developed indigenous ways to prevent and cure diseases by using medicinal plants. The region exhibits great variety of geology, physiography, climate, edaphic and biotic conditions that represent and support diversity of plants species which occur in the wide range of habitat niche. Plant tissue cultures are the core of plant reproduction regeneration biology, which is important for conservation and mass propagation. Modern plant tissue culture technology, promises numerous positive inputs from nano-biotechnology. The application of nanoparticles (NPs) has successfully led to the elimination of microbial contaminants from explants and demonstrated the positive role of NPs in callus induction, organogenesis, somatic embryogenesis, somaclonal variation, genetic transformation and secondary metabolite production processes. Nanoparticles (NPs) have been widely used to improve seed germination, enhance plant growth and yield, enable plant genetic modification, improve bioactive compound production, and achieve plant protection and agronomic practices. The cultivation of MAPs can provide valuable cash for livelihood security of Southern Rajasthan rural people. The government should focus to this sector for research, skill development and conservation to bring out it in to modern age. It can be concluded that NPs may help to optimize growth and developmental changes and this makes the practical application of nanotechnology in the field of plant sciences with respect to the design of controlled environment for in-vitro and in-vivo production of secondary metabolite.

Dr Hema ChandranImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dept. of Biotechnology, Mohanlal

Sukhadia University, Udaipur, Rajasthan

Designation : Guest Faculty

Plant Growth-Promoting Rhizobacteria as Biostimulant for Sustainable Agriculture Hema Chandran*, Prof. Kanika Sharma, Rachna Verma Dr. Hema Chandran, Dept. of Botany, Microbial Research Laboratory, University College of Science, Mohanlal Sukhadia University, Udaipur Prof. Kanika Sharma, Head Dept. of Botany, Microbial Research Laboratory, University College of Science, Mohanlal Sukhadia University, Udaipur Rachna Verma, Research Trainee, Dept. of Botany, Microbial Research Laboratory, University College of Science, Mohanlal Sukhadia University, Udaipur E- mail:[email protected] Sustainable agriculture entails successful management of resources in agriculture to satisfy human needs by enhancing the quality of environment and conservation of natural resources. The objective of sustainable agriculture can be achieved by making use of Plant Growth Promoting Rhizobacteria (PGPR). These are beneficial bacteria that colonize plant roots and enhance plant growth by a wide variety of mechanisms. In the present study, the effect of two plant growth-promoting rhizobacteria Psuedomonas aeuroginosa and Bacillus subtilis was evaluated on tomato growth parameters as well as biological control of early blight of tomato caused by Alternaria solani. The PGPR strains were selected on the basis of their in- vitro plant growth promoting traits like phosphate solubilization, siderophore production and production of indole acetic acid (IAA) etc. The isolates were tested for their efficacy in seed germination and seedling vigor by using tomato seeds in roll towel method. Both isolates showed an increase in both shoot and root length of tomato seedlings compared to control. Antagonistic activity of PGPR isolates against phytopathogens Alternaria solani and Fusarium solani were tested and both isolates exhibited activity against the pathogens. The results obtained in this study are quite encouraging that the rhizobacterial isolates exhibited strong in-vitro plant growth promoting traits. Thus, these isolates can further be evaluated for more plant favorable characteristics as well as their response under field conditions so that these may be developed as successful soil-inoculants for improvement of plant growth and productivity of tomato.

Key words: Sustainable agriculture, PGPR, in vitro assay, Pot assay, Phosphate Solubilization

Dr ABHAI KUMARImage Delegate ID Theme Details


Research


Hindu UniversityDesignation : Scientist

Role of Vitamin D in neurodegeneration and cognitive decline in elderly population

Abhai Kumar*

DBT-BHU Interdisciplinary School of Life Sciences, Institute of Science, Banaras Hindu University, Varanasi, India, PIN-221005

*Corresponding Author Name & Email ID- Dr. Abhai Kumar; [email protected]

Abstract Background:Vitamin D deficiency is very much prevalent in older population due to the decreased cutaneous synthesis and dietary intake of vitamin D. Recent studies have confirmed an association between cognitive impairment, dementia, and vitamin D deficiency. Mild cognitive impairment (MCI) is an early stage of dementia in elderly population. The effect of Vitamin D and release of pro-inflammatory cytokines from polymorphonuclear leukocytes (PMNs) during oxidative stress in MCI is still unknown in Alzheimer’s disease pathology. Aim: Therefore, the present study was conducted to investigate the changes in cognitive performance, white matter integrity, and their association with Vitamin D level, pro-inflammatory cytokines level in PMNs oxidative stress in neurodegeneration. Methodology: Fifty cases of MCI and controls (55-75 years) were subjected to Mini Mental State Examination (MMSE), diffusion tensor imaging (DTI) followed by estimation of vitamin D in serum, of MCI and control population. The subjects having deficient level of Vitamin D, the cytokines mainly interlukin-1beta (IL-1beta), Tumor necrosis factor alpha (TNF-1apha) and iNOS level and expression were estimated in PMNs.Results: The MMSE scores of MCI subjects were (28±2 - 22.6±1) compared with controls (28±1- 29±1). DTI metrics fractional anisotropy (FA) values in right and left frontal lobe, fornix, corpus callosum, while apparent diffusion coefficient (ADC) values in right temporal lobe, hippocampus head, corpus callosum right, and forcep major were significantly altered in MCI as compared with controls. Vitamin D level mainly 25 (OH)D level was Reference: Kumar A*, Smita Singh, Anup Singh, Ashish Verma and Vijay Nath Mishra. Diffusion tensor imaging based white matter changes and level of antioxidant enzymes for early diagnosis for mild cognitive impairment . Intenrational Journal of Neuroscience. 2018;ISSN-0020-7454; * Corresponding Author

Dr Puneet ChauhanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-NBRI


A plant growth-promoting Paenibacillus lentimorbus NRRL B30488 (B30488) was isolated from cows'milk. The strain was characterized for its plant growth promoting attributes and stress toleranceunder in vitro and in vivo conditions. One of the most important traits for any plant growthpromoting rhizobacteria is rhizosphere colonization or competence for its successful functioning inlive soil. B30488 has been reported for it efficient and vigorous colonization in the rhizosphereand phytosphere of many agricultural, horticulture, medicinal, floriculture crop plants ingnotobiotic and live soil conditions. B30488 have been utilized not only for plant growth promotingattributes but also for ameliorating the biotic and abiotic stresses in different hosts. Earlier, wehave reported B30488 for inducing the nodulation in chickpea and enhances the tobacco growth viaextenuating the virulence of cucumber mosaic virus. Recently, B30488 was also reported for inducingthe autophagy response towards biological control against Sclerotium rolfsii infection andalleviating the nutrient deficiency-induced stress in Cicer arietinum L. Apart from PGP attributesand ameliorating the abiotic and biotic stress B30488 was also evaluated for eliminating thepathogenic microbial load in municipal solid waste, toward converting it to a beneficial PGPRenriched organic manure. Many more hidden beneficial attributes are still yet to come from this PGPRB30488 to serve human welfare.

Ms Vinita ThorechaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Mohanlal

sukhadia university, UdaipurDesignation : M.Sc.

Biotechnology

Immunomodulators are medications used to help regulate or normalize the immune system. Tinosporacordifolia works as immunomodulator and its aqueous extracts is useful for immuno-modulatoryactivity.It has many medicinal properties like anti-diabetic, anti-inflammatory, anti-arthritic,anti-allergic, anti-stress, anti-malarial, hepatoprotective, immunomodulatory and anti-neoplasticactivities.It is used in ayurvedic medicine in the treatment of jaundice, chronic diarrhea, cancer,dysentery, bone fracture, asthuma, skin disease, snake bite, eye disorders, improve the immunesystem and body resistance against infections. T. cordifolia extract in liver act as immunodulator,minimizes damage to the liver tissue and decrease the fibrosis in animal models of reversible andirreversible liver injuries induced by carbon tetrachloride, also increase the phagocytic andkilling activity of macrophages and reduce oxidative stress/injury indicating its protective role inliver tissue. Tinospora cordifolia control the drug-resistance Mycobacteriumtuberculosis infection by inducing Th1 immune responses. T. cordifolia extract has antitumorpotential against the skin carcinogenesis. The root of this plant is for antistress, anti-leproticand anti-malarial activities and leaves are rich in protein, calcium and phosphorus.It is used fortreating diabetes mellitus, reduction in blood glucose and brain lipids. Pre-treatment with T.cordifolia was useful in protection against mortality induced by intra-abdominal sepsis followingcoecal ligation in rats and protection in cholestatic patients against E. coli infection. Theanti-stress and tonic property of the plant shows good response in children with moderate degree ofbehaviour disorders and mental deficit. It also improved the I.Q. levels.Tinospora cordifolia isbeneficial in arrhythmias and microbial infections, inflammatory and allied diseases of musculoskeletal system.Tinospora cordifolia with Zingiber officinale has used in rheumatoidarthritis. Ecdysteroids isolated from the plant shows protein anabolic and anti-osteoporoticeffects in mammals.It reduces the pain in patients suffering from rheumatoid arthritis. Tinosporacordifolia is an effective antihyperglycemic drug used in the treatment of Diabetes mellitus.Anti-HIV effects of Tinospora cordifolia was revealed by reduction in eosinophil count, stimulationof B lymphocytes, macrophages and polymorphonuclear leucocytes and hemoglobin percentage. Aditerpenoid from Tinospora cordifolia is useful in anti-tumor effects chemopreventive potential indiethylnitrosamine (DEN) induced hepatocellular carcinoma (HCC) in rats.It killed the HeLa cells invitro and thus act as an anti-neoplastic agent. The effect of Tinospora cordifolia extracts wasbetter than doxorubicin treatment. It has no side effect and toxicity.

Ms Pallujam AshaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Manipur University, Manipur, India

Designation : Junior Research Fellow

Banana streak disease is a major threat to banana production and improvement worldwide. Out of the120 banana mats/genotypes collected from the entire North East (NE) India, 41 germplasms werecharacterized for endogenous BSV (banana streak virus) sequences (eBSVs) using allele specificprimers targeting the RT/RNase region of badnaviruses. Out of 10 Musa acuminata genotypes (AAA andAA), none was tested positive for activable eBSV alleles. Out of 23 Musa balbisiana genotypes (BBand ABB), all were harbouring activable eBSV alleles. All the 41 isolates shared an identity of99-100% which shows only a variation up to 1%. The present finding indicates the presence of eBSV inbanana isolates of North East India. Due to the ability of eBSV to become activated and causeepisomal infection under certain conditions, the eBSV based vertical spread of BSV has been nowrecognized a serious threat to the banana production and genetic improvement worldwide. The eBSVhave a considerable impact on the outbreaks of banana streak disease recorded in countries whichwere previously free of BSV.

Prof Anita JoshiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Poddar

International College JaipurDesignation : Associate prof.

Boerhaavia diffusa L. (Nyctaginaceae), commonly known as 'Punarnava' in the Indian system of medicine, is a perennial creeping herb found throughout the waste land of India. It is use since beginning of Ayurvd era for various therapeutic benefits. The Plant in whole or its peculiar parts (Aerial parts and Roots) have a numerous medicinal properties and are used by endemic and tribal people in India and Unani medicine in Arab countries to show Anti-bacterial, hepato-protective, hypo-glycemic, anti-proliferative, anti-estrogenic, anti-inflammatory, anti-convulsant, anti-stress and anti-metastatic activities and also in treatment of stress, dyspepsia, abdominal pain, inflammation, jaundice. Various phytochemical, pharmacological, experimental and clinical investigations are done on Boerhaavia diffusa by many scientist, researchers etc., to clearly understand the ancient Ayurvedic, Endemic and tribal usage of Punarnava. The name Punarnava itself means ‘Rejuvenation’. It contains various categories of secondary metabolites, for example, flavonoid glycosides, isoflavonoids (rotenoids), steroids, alkaloids, and glycosides. Boerhaavia diffusa serves as a rich source of primary metabolites which can be used as raw material in industries. The present study was designed to evaluate the phytochemical activity of leaf, stem and callus. Maximum Carbohydrates and lipid content was recorded in Leaves. Also Maximum Protein content was found in Callus.

Ms sarika yadavImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-Indian

Institute of Toxicology Research, Lucknow, India

Designation : PhD

Assessment of Cross-reactivity of Wheat proteins (crude extract) and Ovalbumin: In silico prediction and its validation in Balb/c mice model Sarika Yadav1,2, Somya Asthana1 and Anurag Tripathi1,2, * 1Food, Drug and Chemical Toxicology Group, CSIR-Indian Institute of Toxicology Research Vishvigyan Bhavan, 31, Mahatma Gandhi Marg, Lucknow-226001 Uttar Pradesh, India 2Academy of Scientific and Innovative Research (AcSIR), CSIR-IITR, Lucknow. [email protected] Cross-reactivity (CR) occurs when an adaptive immune response to an allergen causes reactivity to another allergen that are structurally related to the inducer. CR have been more often described between phylogenetically close species, however, CR among phylogenetically distant species is also known. The present study was carried out to assess the cross reactivity between two taxonomically distant food proteins. Cross-reactivity of Ovalbumin to Wheat proteins was examined by in silico allergen informatics and was further validated through in vivo studies in female Balb/c mice. For testing the cross-reactivity & allergic potential, the animals were either sensitized with Ova followed by wheat challenge or vice versa. Thereafter, the parameters related to systemic allergic reactions were measured in blood & lavage. Different allergic parameters, like specific IgG1, IgG2a, IgE, and histamine release were estimated through ELISA. In silico analysis revealed that among the Wheat proteins, Serpin was phylogenetically nearest food protein to Ovalbumin with more than 35% sequence similarity in a fragment of 80 amino acids which comply with the allergenicity criteria of WHO/FAO guidelines. Cross reactivity of Ovalbumin with Wheat proteins was clearly seen in both the test groups as evident by hypersensitivity symptoms and a positive reaction to type-1 skin test in each group. In both the groups, total IgE & IgG1 were found significantly higher as compared to control, but severity of the systemic and asthmatic allergic responses was less in the mice sensitized with Wheat extract and then challenged with Ova, as compared to the reciprocal test group. The outcomes of the present study suggest that, individuals allergic to Ovalbumin may develop allergic reactions against wheat proteins, however, the study needs further clinical validation.

Ms Sandeep kumarImage Delegate ID Theme Details


Research


lucknowDesignation : research

scholar

Background: The fish stock can be defined as equivalent to a population which is at least partially, reproductively and geographically isolated from other populations belonging to the same species. The stock of high growth rate and low mortality should be identify and adopt for pisciculture in order to get the higher yield. The different stocks of the fish can be identified using parasite as a biological tag. The parameters such as prevalence, intensity and abundance of fish parasites have been taken into consideration for the identification of different fish stocks. Problem: The ideal tag parasite is that which has different levels of infection among localities and persist in the fish for a long period of time and can be easily detected and identified and it should not cause a serious damage to the host. The present paper deals with the use of fish parasite as a biological tag for stock delineation and identification. Methodology: The parameters such as prevalence, intensity and abundance of the fish parasite are widely used for the segregation and identification of different stocks of fish in all over the world. The various methodologies which are used for the identification of fish and parasite for stock delineation have been discussed in the present paper. Results: A survey of literature was carried out in order to find out the information on the use of fish parasite as biological tag for the identification of fish stock. Various data base was used to collect the information which showed that very little work has been carried out on the fish of Indian water. The different methodologies for identification of parasite and fish along their utility have been discussed in the present paper. Conclusions: The identification and segregation of different fish stocks is considered to be essential for determining the status of the fish in natural environment and for conserving them via fisheries management.

Mr Rameshwar JanguImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bihar Agricultural University,

Sabour, bhagalpur, Bihar, 813210


Abstract: Among all the horticultural crops, vegetables play a key role in food as well as nutritional security and economic growth of the country. India is the world’s second largest producer of vegetables next to China. Lettuce response is greatly influence by many elements viz N, P, K and micronutrients as well as optimum spacing in respect of its growth and yield. Nitrogen generally used in leafy vegetable production. Much nitrogenous fertilizer such as urea, ammonium nitrate, ammonium sulphate or calcium nitrate significantly affects fresh and dry plant weight, plant diameter and total marketable leaves. Crop absorb nitrogen from the soil in the form of ammonium (NH4+) and nitrate (NO3-), which is converted into NH4+ to forms of proteins and other N containing substance in plants. This leafy vegetable requires a high rate of nitrogen for its life cycle. Indiscriminate use nitrogen fertilizer to increase crop yield disturbed the equilibrium balance of macro and micro nutrient in the soil, caused pollution, decreased crop quality and thus a great part of the nation’s resources became useless. Plant spacing for lettuce cultivation is an important criterion for attaining maximum vegetative growth and an important aspect of agriculture production for maximizing the yield. Optimum plant spacing ensures judicious use of natural resources and makes the intercultural operations easier. It helps to increase the number of leaves, branches and healthy foliage. Densely planted crop obstruct the proper growth and development. On the other hand, wider spacing ensures the basic nutritional requirements but decrease the total number of plants as well as total yield. Keywords: Lettuce, spacing, nitrogen levels.

Mr dheerendra pratap mallImage Delegate ID Theme Details


Research


Institute of Chemical Biology, kolkata

Designation : Senior research fellow

ABSTRECT Background : The eukaryotic transcription is a multistep process. Regulation of pausing event is the most important step for developmental genes (1). Many of the key questions that still remained unanswered. FKBP5 is one of the major co-chaperone of HSP90 and it helps in the proper folding of several other proteins. FKBP5 is implicated in many diseases by regulating some of the signaling pathways like MAP- kinase pathway, AR (Androgen Receptor) pathway etc. Recent studies have shown a role of humanHsp90 protein in regulating pausing events in Drosophilla S2 cells through regulation of NELF(Negative ELongation Factor) activity (2). P-TEFb In this project we found out a role of FKBP51 in P-TEFb mediated regulation of transcription. Problem : To elucidate the role of FKBP5 in P-TEFb mediated transcriptional regulation. METHOD : Mass Spectrometric analysis for identifying the novel associations between P-TEFb and other novel factors followed by Immuno-precipitation analysis. subsequently interaction analysis followed by functional importance of interaction. Target genes would be identified by high-throughput RNA-Seq analysis. Expression of individual target genes would further be tested through quantitative Real-Time PCR analyses. RESULTS: We identified association of FKBP5 with CDK9. We observed a negative effect of FKBP5 on P-TEFb activity. We have observed a global increase in phosphorylation level of Ser2 CTD as well as Ser5 CTD. We have tested the domain specificity of the FKBP5 interaction with CDK9. We have seen that N-terminas domain of CDK9 in responsible for interaction with FKBP5 Consistent to the available studies we also got to the same result that the N-terminus of CDK9 is responsible for interaction with CyclinT1.We performed In-vitro sequestration assay and we saw that FKBP5 have potential to extract out CDK9 from P-TEFb complex which is the probable mechanism for the present story. Conclusion : In our present study, we explored the role of FKBP5 in transcriptional regulation mediated by P-TEFb. We found out thet FKBP5 have potential to extract-out CDK9 from P-TEFb complex to inactivate it. Through In-vitro and cell based assays we have shown functional and physiological significance of it. References : 1. Adelman, K., and Lis, J. T. (2012) Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans, Nat Rev Genet13, 720-731. 2. Sawarkar, R., Sievers, C., and Paro, R. (2012) Hsp90 globally targets paused RNA polymerase to regulate gene expression in response to environmental stimuli, Cell149, 807-818.

Mr UTTAM MAJIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : UCM,

IPGME&R, KOL-20Designation : Research

Scholar

Background: Hypertension is known to be a major risk factor for acute ischemic heart disease . However the normalization of the elevated blood pressure using currently available antihypertensive therapy therapeutic regimen resulted in only 8% decrease in the risk of acute ischemic heart disease . We have recently reported that synthesis of cortexin , an antihypertensive protein hormone in the kidney cortex cell. None of antihypertensive drug is capable of stimulating cortexin synthesis . Systemic increase of NO stimulated cortexin synthesis and acetyl salicylic acid (aspirin) stimulates systemic NO synthesis. Objective: We determined the effect of oral aspirin (150mg/70kg) ingestion on the elevated systolic and diastolic blood pressure. Cortexin was also found to be a potent inhibitor of platelet aggregation. Methods: Newly diagnosed patients with hypertension ,(n=50) who never received any antihypertensive medication at presentation were asked to participate in the study by ingesting enteric coated aspirin (150mg/70kg) only after the participants took a full meal. The blood pressures were measured after 3h of ingesting the drug. Cortexin was determined by enzyme linked immunosorbent assay (ELISA). Results: The both systolic and diastolic pressure which were 160.63±13.85 mmHg, 96.63 ±8.03 mmHg at presentation were found to become normalized(123.33±10.30mmHg systolic , 82.5±5.5 mmHg diastolic respectively) after 3h of ingestion of aspirin with concomitant increase of cortexin level from 0nM (before aspirin ingestion) to 9.23±0.042nM (after the ingestion) of the compound (p?0.0001) in these patients. Conclusion: Since cortexin is reported to be a potent inhibitor of platelet aggregation, and was found to be a powerful normalizer of hypertension, aspirin might be useful for the reduction of risk factor for CAD both through the normalization of the hypertension and inhibition of platelet aggregation.

Dr ANUPRITA RAYImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : N.R.R.I

Designation : S.R.F

Rice is the major food crop for more than two billion people in Asia and hundreds of millions of people in Africa and Latin America. It happens to be the staple food of the people in the eastern, southern, south western parts of India. Now a days, rice growers are facing various pest and diseases problem one such reported disease creating havoc is false smut. The causal agent is Ustilaginoidea virens (Cooke) and its perfect stage is Villosiclava virens. This new emerging disease of rice contributes around 20-25% of yield loss of rice annually. SSR markers are extensively used in genetic diversity, population genetic structure studies. SSR has been used for deciphering diversity in many fungal plant pathogens. In the study, 35 SSR markers were tested, 17 SSR primers produced reproducible polymorphic bands and were used for the genetic survey of isolates. Principal component analysis (PCA) of pairwise genetic distance between individuals was performed using GenALEx to resolve the distribution of variation at different hierarchical levels. Our results demonstrate that there was a low level of genetic variation in all U. virens populations with a similarity of over 60%. The result of the PCoA was consistent with the UPGMA clustering analysis. The findings suggested that the molecular variation and differentiation was associated somewhat with geographical origin but not for all of the isolates. Keywords: SSR-Simple sequence repeats, UPGMA-Unweighted pair group method with arithmetic mean, PCoA-Principal coordinates analysis

Mr SUSHIL DUBEYImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CENTER OF

BIOTECHNOLOGY, UNIVERSITY OF ALLAHABAD

Designation : P.hD. SCHOLAR

The purpose of this study is to determine the anti-hyperglycemic activity of P. opuntiae, P.fossulatus, P. flabelletus which was cultivated on paddy straw substrate. The fruiting body was airdried and then formed the fine powder by using mixer and grinder. The powder was then subjected forthe extraction in ethanol solvent by using soxhelet for the 48 hours. The extract was separated fromsolvent by using rotatory evaporator. The extract then dissolved in distilled water and separated inchloroform fraction. These fractions were tested for ?-amylase and ?-glucosidase inhibitoryactivity in vitro by using reducing sugar method. According to our results P. fossulatus at 500?g/ml concentration of chloroform fraction showed maximum i.e. 96.56 % and 78.91 % inhibition of?-amylase and ?-glucosidase enzymes respectively. Hence, P. fossulatus showed a goodanti-hyperglycemia property and can be given as an alternative diet therapeutic with othertreatments of type-2 diabetes.

Mr MOHD KAMRANImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-INDIAN INSTITUTE OF CHEMICAL

BIOLOGYDesignation : Research

fellow

Background: Visceral leishmaniasis (VL) is an immunosuppressive disease caused by protozoan parasite Leishmania donovani. So far no effective vaccine or drug is available for this disease. Also there is no effective clinical diagnostic tool based on recombinant antigens for all endemic regions. Problem: For clinical diagnosis invasive methods were being used. Nowadays for kit-based diagnosis of VL, recombinant kinesin-related antigen like rK39, rK28 and rKE16 are widely used commercially. However, these antigens often show cross-reactivity with endemic healthy controls. Thus, a good diagnostic target antigen is still lacking, so we are trying to identify novel antigents and development of a better diagnostic tool for non-invasive diagnosis of VL. Methods used: We used our earlier published RNA-seq data for antigen selection based on human stage (amastigote) expression (1). We used CRISPR for knockout of this gene (2). Further we accessed the immunoreactivity of this antigen in patients of visceral leishmaniasis through western blotting and ELISA. Finally we developed immunochromatographic strip test for rapid diagnosis of visceral leishmaniasis patients. Major Results and conclusions: We found DUB is not essential for parasite viability in promastigote stage. We detected antibodies in the Indian and Brazilian patient’s sera against this antigen (DUB). The reactivity and sensitivity were found to be more than 95% in the patients tested by ELISA. The immunochromatographic test was developed for the diagnosis of visceral leishmaniasis patients using DUB. Together this study will help us to diagnosis of patients in different endemic regions with high specificity and sensitivity. Also structural and functional characterization of deubiquitinases (DUB) will pave the way to further validate its therapeutic potential in future. References: (1) Mohammad Shadab et al, Front. Cell. Infect. Microbiol, 05 February 2019: doi.org/10.3389/fcimb.2019.00017. (2) Beneke T et al R Soc Open Sci. 2017 May 3; 4(5): 170095. doi.org/10.1098/rsos.170095.

Ms Subhalakshmi ShijagurumayumImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Manipur


scholar

: Manipur has rich variety of indigenous rice (Oryza sativa L.) germplasms. The scented ricevarieties of Manipur are commonly known as Chakhao which means delicious rice. The chakhao varietiesare diverse locally adapted aromatic varieties with colour ranging from white, red to purple orblack. There is a need to collect and properly characterise these aromatic varieties before they arereplaced by high yielding types .Five aromatic black rice varieties and one non-aromatic ricevariety IR64 were analysed for their nutritional quality attributes including Iron, Zinc, Copper,Manganese, Magnesium, Calcium content and proximate composition. Mineral analysis was done usingdiacid digestion method by Bhargava and Raghupathi,1993 and for proximate analysis AOAC method,2000was followed. GC-MS analysis was done to study the different volatile compounds in dichloromethaneextract of rice and metabolite profiling of compounds was done using method by Weckwerth et al,2004.Iron content was found to be ranging from 15.33 to 57.66 µg/g. Zinc content ranges from 4.92 to8.71 µg/g. Copper content ranges from 0.78 to 5.74 µg/g. Manganese content ranges from 9.84 to53.94 µg/g. Calcium content ranges from 110.86 to 217.06 µg/g. Athebu ium variety had the highestmoisture content (13.1%), Manui Kazik had the highest ash content (1.74%), Athebu ium and ManuiKazik had the highest fat content (4%),Manui Kazik had the highest fibre content(2.15%),Athebu iumhad the highest protein content (14%) and IR64 had the highest carbohydrate content. The differentclass of volatile compounds identified in the study are alkanes, steroid and sterols, alcohols,aldehydes, fatty acids, terpenes, esters, alkenes, amide, ethers, ketones, vitamin, alkyne, phenoliccompound and aromatic hydrocarbons. PCA analysis was carried out to study the variation among therice varieties based on the major volatile compounds. This study provides a comprehensive andunbiased picture of metabolites belonging to predefined group such as organic acids, sugars, fattyacids and amino acids. PCA analysis was carried out to study the variation among the varieties basedon metabolite composition. The black varieties have higher mineral content and nutritional valuethan the non-aromatic type and they show variation in their volatile and metabolite composition.

Dr DINESH KUMAR PaulrajImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : green life

siddha Designation : B.S.M.S

Corresponding Author: [email protected] Background: Pain its occur in our body due to many reason. Major and the non identified reason which is we identified in our clinical practice and research and that is the normal length of the muscles extension is reduced due to strains or lesser usage of the particular muscles. It will be cured simultaneously in the small level problem. Example playing some game after long gap some pain occurs in particular area and it will be reduced and cured shortly. The reason for that pain is the particular muscle doesn’t extend its maximum length and it losses the flexibility. Similarly some sudden extension of some muscles will produce strain and for that strain the muscle cannot extend . we give the treatment and relieve only by loosening the muscles with oils and massage and the pain can reduced or relieved within particular time to the patient. It only applicable in the patient who got strain, low level of physical movements or any disease related to the muscular. We can find out immediately by apply the muscle relaxant oil and know the status of the problem . Conclusion: Applying oil and relaxation of the muscles will helps to reduce or cure the problem of pain in selective patients without any internal treatment. References: 1.Kunapadam mooligai 2. Pothu maruthuvam 3. Nam nattu maruthuvam 4. Pathartha guna vilakkam

Ms Naorem Premita DeviImage Delegate ID Theme Details


Research



Scholar

Liverworts (Marchantiophyta/ Hepaticae) consists of the most primitive bryophyte members which arepoikilohydric, non-vascular and non-seeded plants having gametophyte dominant life cycle. In thefield of plant sciences, bryophytes are one of the poorly described group because of their miniaturebody, difficult taxonomy and less income generation value in day to day life although havingremarkable ecological and phylogenetic significance. Two plant forms are recognized in liverworts,namely, leafy and thalloid. Out of the total 81 families of liverworts, thalloid forms arerepresented by 30 families and 58 genera. In the latest global checklists of liverworts, they arerepresented by about 750 species constituting approximately 10% of the total liverwort diversity. InIndia, about 31 genera and 139 species are known to occur. Systematists all over the world now relyon molecular phylogeny for classifying organisms. However, morphological and anatomical charactersare the first and basic step that yield the most effective data for preliminary identification intaxonomic studies. Manipur, one of the North-East states of India, comes under the Indo-BurmaBiodiversity Hotspot and is highly rich in flora and fauna composition. A few earlier collections ofliverworts from the state revealed the presence of 15 thalloid genera but no detailed descriptionwas given by any workers. In the present investigation, the authors were able to collect 12 generaof thalloid liverworts and micromorphological diversity was studied by using phase-contrastmicroscope MOTIC BA210. Specimens were deposited in Manipur University Museum of Plants (MUMP)following the preservation method of Vanderpoorten et al. (2010). Description of each genus based ontheir morphology and anatomy is provided for the first time from this region. Two genera viz.,Cyathodium Kunze and Pallavicinia Gray nom. cons. were added to the state. A generic key to thethalloid liverworts of Manipur is also incorporated. There is a great potential for more discoveryof liverworts in Manipur as major part of the state is not yet explored.

Mr Rudranil DeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-Indian Institute of Chemical Biology

Designation : Project Assistant level III

Regulation of mitochondrial dynamics and viability of human cancer cells by Macrophage migration inhibitory factor through CD74-NF?B signalling Rudranil De*, Uday Bandyopadhyay *Project assistant level III, Infectious Diseases and Immunology Division; CSIR?Indian Institute of Chemical Biology. 4, Raja S. C. Mullick Road, Kolkata?700032, West Bengal; India. E-mail: [email protected]

Abstract: The instrumental role of macrophage migration inhibitory factor (MIF) in many cancer cell proliferation is explicit; although which specific roles the cytokine plays to block apoptosis preserving cell growth is still ambiguous. The present study explores different cancer cell lineages (AGS, HepG2, HCT 116 and HeLa) and the results indicated that silencing of MIF severely deregulates mitochondrial structural dynamics and triggers apoptosis. Apoptosis was evident by flow-cytometric analysis. Immuno-confocal and western blot analysis revealed enhanced mitochondrial Bax translocation along with cytochrome c release, down-regulation of Bcl-xL and Bcl-2 as well as up-regulation of Bad, Bax and p53 suggesting programmed cell death. Immunoblot data also indicate a concerted down-regulation of Opa1 and Mfn 1 along with a significant mitochondrial translocation and fissogenic phosphorylation of Drp1, cumulatively causing mitochondrial fragmentation upon MIF silencing as visualised in live-cell confocal microscopy. Interestingly, MIF silencing has also been found to be associated with decreased NF-?B activation, silencing which in turn increases mitochondrial fission and cell death. In addition, silencing of CD74, the cognate receptor of MIF, remarkably increases mitochondrial fragmentation besides preventing cell proliferation, inducing mitochondrial depolarization and increasing apoptotic cell death. In conclusion, the study proposed that MIF, through CD74, constitutively activates NF-?B to control mitochondrial dynamics and stability for promoting carcinogenesis averting apoptosis.

References: 1. Baumann, R., Casaulta, C., Simon, D., Conus, S., Yousefi, S., and Simon, H. U. FASEB J 2003. 17, 2221–2230. 2. Wilson, J. M., Coletta, P. L., Cuthbert, R. J., Scott, N., MacLennan, K., J. B., Jin, K. K., Bucala, R., and Hull, M. A. Gastroenterology 2005, 129, 1485–1503. 3. Martin, P., Furman, R. R., Rutherford, S., Ruan, J., Ely, S., Greenberg, J., Coleman, M., Goldsmith, S. J., and Leonard, J. P. Leuk. Lymphoma 2015, 56, 3065–3070. 4. Westermann, B. Nat. Rev. Mol. Cell Biol 2010. 11, 872–884. 5. Alirol, E., and Martinou, J. C. Oncogene 2006, 25, 4706–4716. 6. De, R., Mazumder, S., Sarkar, S., Debsharma, S., Siddiqui, A. A., Saha, S. J., Banerjee, C., Nag, S., Saha, D., and Bandyopadhyay, U. Free Radic. Biol. Med 2017. 113, 424–438.

Ms Lourembam Chanu BonitaImage Delegate ID Theme Details


Research



Potential of some underutilized legumes as functional food Lourembam Chanu Bonita1, and G. A. Shantibala Devi1*, Subhalakshmi Shijagurumayum1, Ch. Brajakishor Singh2 1 Department of Life Sciences, Manipur University, Imphal – 795003 2 Institute of Bioresources and Sustainable Development, Imphal - 795004 * E-mail id: [email protected]

Abstract: India is the largest producer, consumer and importer of pulses. But many legumes like lima beans are still neglected in India. Some lima bean varieties were collected from Manipur and their chemical composition and functional properties were studied. The proximate composition of the seeds showed significant differences among the varieties. Protein content of the seeds were quite high. Among the minerals studied phosphorus was present in the highest amount. Calcium and iron were also present in appreciable amounts. Phenolic compounds have been associated with many health benefits. The beans analyzed in this study showed the presence of high amounts of total phenolic and flavonoid contents. Antioxidant properties of the beans were also studied using three in vitro assays - DPPH radical scavenging activity, ABTS assay and reducing power assay. Phytochemicals with health benefits have been detected by gas chromatography – mass spectrometry. Some of the compounds detected which reduce risks of diseases like cardiovascular diseases, cancer and diabetes include various fatty acids, tocopherols and phytosterols. Functional properties of flour of the beans were also studied to assess their applicability as ingredient of food products. Bulk density, least gelation concentrations, syneresis, foaming capacity, foam stability, emulsifying activity, emulsion stability, water absorption capacities, oil absorption capacities, water absorption indices and water solubility indices of the beans were also investigated and showed significant differences among the varieties. Lima beans are nutritionally rich and good sources of bioactive compounds with health benefits which can be used as functional food.

Mr Abhishek KumarImage Delegate ID Theme Details


Research


AllahabadDesignation : PhD student

Diabetes, an unresolved metabolic disorder and lead contamination are prevalent problems in thecontemporary society. Previously, reported suggest that either diabetes or lead exposure resulted inhepatotoxicity in male Wistar rats. The aim of this study was to evaluate whether diabetic ratsexposed to lead demonstrate a higher degree of hepatotoxicity when compared with lead-exposedcontrol rats. Diabetes was induced by injecting single dose of streptozotocin (40 mg/kg bodyweight). Control and diabetic rats were exposed to lead through oral gavage for a period of 21 daysand assessed for hepatic and oxidative end points. The relative weights of liver and spleen weresignificantly decreased in diabetic rats. Significant reduction in hepatic antioxidant enzymeactivity levels and glutathione levels were observed in diabetic rats with an elevation in levels ofsuperoxide anions, hydrogen peroxides, lipid peroxidation. Mild histopathological malformations wereobserved in the liver of the diabetic rats. Similar hepatic and oxidative toxicity was observed inlead-exposed control rats. Further, lead exposed diabetic rats showed additional deterioration inhepatic end points and noteworthy elevation in oxidative toxicity suggesting that treatment withlead exacerbates hepatic toxicity in streptozotocin-induced diabetic rats. The ameliorative efficacyof aquous extract of C. Carandas was analysed in diabetic rat exposed to lead. Study shows thesignificant hepatoprotective activity of extract.

Ms Pooja ShindeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jijamata

College of Science and ArtsDesignation : assitant

professor

In the present investigation an attempt was made to study the effect of different concentration of sodium azide (0.01 M to 0.06 M) at room temperature on peroxidase isozyme patterns in Mung bean (Vigna radiata L.) with an objective of finding it mode of action i.e. whether it has promoting or inhibitory effect on the enzyme synthesis and whether the action is specific or random. SA at all concentration reduced the rate of seed germination, root, and shoot and seedling growth as compared to control. The concentration of 0.03M was adjusted as LD50.PAGE analysis of peroxidase isozyme of 8 day old control seedlings showed only three bands of peroxidase isozymes. The concentration of 0.004M and 0.005M showed presence of seven distinct peroxidase bands. It is an established fact that when plants are exposed to stressful condition harmful substances like H2O2 increases and cause significant damage to plant cells. A major hydrogen detoxifying system in plant cell is the peroxidase isozymes which catalyzes the conversion of H2O2 into H2O and nascent oxygen. The observed increase in number of peroxidase isozymes in the present investigation might be due to the genetic stress caused by deleterious effects of sodium azide as it is a potent mutant. The result suggest that SA induces synthesis of peroxidase isozyme and the action seems to be specific.

Mr Amit Kumar SinghImage Delegate ID Theme Details


Research


Biochemistry, University of Allahabad

Designation : Phd Student

Background: Diabetes mellitus is a metabolic disorder which affects individuals all around the world. Imbalanced blood glucose levels typically lead to various problems in organs that are rich in microvasculature, including nephropathy. Diabetic nephropathy (DN) is a high risk factor for vascular disease, and is common among patients with type 2 diabetes (T2D). Hyperglycemia resulted from diabetes causes oxidative stress and which in turn induces the production of reactive oxygen species (ROS). ROS shows detrimental effect to cell membranes, inactivates antioxidant enzymes and changes the expression of antioxidant gene and ultimately contributes to the pathogenesis of DN. Chlorogenic acid (CGA) is a phenolic compound from the hydroxycinnamic acid family. The compound’s chemical structure consists of a caffeic acid moiety and a quinic acid moiety. Chlorogenic acid has been extensively studied since it is widely distributed in plants, is one of the main polyphenols in the human diet, and it possesses many health-promoting properties. Method: In the present study an effort have been made to explore the renoprotective effect of CGA on diabetic nephropathy in streptozotocin induced type 2 diabetic rats. CGA was administered orally with gavage for 4 weeks. Body weight, blood glucose, total cholesterol (TC), HDL-cholesterol (HDL-c), triglycerides (TG), urea (BUN) and creatinine levels were subsequently examined at the end of administration. Catalase, Superoxide dismutase activity, malondialdehyde content and glutathione peroxidase levels were also assessed in kidney tissues Results: It has been found that the CGA feeding significantly decreased the levels of serum blood urea nitrogen, serum creatinine, and fasting blood glucose in rats. Also, TG, and TC levels were significantly decreased following CGA administration, whereas HDL-c was increased. CGA treatment significantly increased the activity of catalase and SOD and significantly decreased malondialdehyde level in renal tissue, as compared with the control groups. Conclusion: These data clearly demonstrated the renoprotective effects of CGA against the development and progression of T2D nephropathy in rats. The underlying mechanism of this protective effect may be associated with glycemic control, lipid metabolism, and anti-oxidative functions. References: 1. Zhang, S.; Xu, T.; Yu, X.; Wu,Y.; Sui, D. Exp. Ther. Med. 2017, 14, 383-390. 2. Sharma, U.K.; Kumar, R.; Gupta, A.; Ganguly, R.; Pandey, A.K. 3 Biotech, 2018, 8:212.

Dr Sourabh TiwariImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Govt. Arts,

commerce and science college, Sukhtawa, M. PDesignation : Faculty, Department of Zoology

Abstract Major challenges in conventional chemotherapy are related to toxicity on healthy proliferating cells and multi-drug resistance (MDR) against anticancer agents. Gemcitabine is one of the widely used chemotherapeutic drug in the drug delivery system. Recent advances in nanoparticluate drug delivery offer better treatment of multidrug-resistant cancers and lower immunotoxicity. Nanoparticles offer increased precision in chemotherapeutic targeting of pancreatic cancer. SLNs are produced from biocompatible and biodegradable lipid materials, making them a promising therapeutic strategy for drug targeting and delivery, and surmounting the inherent limitations of regulation acceptance. The aim of the present study was to encapsulate Gemcitabine in solid lipid nanoparticles (SLNs), thereby prolonging its anti tumour activity and cellular uptake and enhancing its bioavailability. In this study, we proposed Gemcitabine loaded solid lipid nanoparticles (SLNs) as a drug delivery system for pancreatic cancer chemotherapy. The anti-cancer activity of the drug was evaluated using cultured carcinoma cells in MiaPaCa-2 cells. Evaluation of anti-carcinogenic potential by Annexin-V-FITC/PI apoptosis assay following 48 h treatment with SLN and native drugs delineated significant differences, establishing better potential efficacy of nano-engineered drugs. Fluorescence spectrophotometry was used to quantify cellular uptake of the drug. Higher internalizing ability, better antitumor efficacy and lesser cytotoxicity of SLNs was attributed to increased accumulation of drugs in cancerous cells. Thus our results implied that the use of Gemcitabine loaded Solid lipid nanoparticles as promising drug delivery systems for pancreatic cancer therapy. Their use offers improved pharmacokinetic properties controlled and sustained release of drugs and, more importantly, lower systemic toxicity. These preliminary in vitro results suggest that SLN could be anticipated as alternative drug delivery system. Keywords Pancreatic cancer, Chemotherapy, Gemcitabine, Nanotechnology, Solid lipid nanoparticles.

Dr Shashank TiwariImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Babasaheb Bhimrao Ambedkar Central

University LucknowDesignation : Faculty

The upland soil plays a crucial role in the CH4 oxidation on higher rate. The CH4 oxidation in soilsis exclusively mediated by aerobic methanotrophs. Due to anthropogenic interventions the naturalforests are gradually being converted into agricultural lands. These activities strongly affect themethanotrophs activity in such disturbed soils. However, information regarding the impact of landuse changes on soil methanotrophs community structure in upland soils is in initial state.Therefore, differences in methanotrophs abundance and diversity across different land-uses i.e.natural forest, mixed forest, savanna, and agriculture ecosystems in dry tropical soils situated atVindhyan region were investigated. The abundance of the soil methanotrophs at agriculture sitereduced considerably with increasing soil NH4+ concentrations and decreasing soil water contents.The results suggested that land use changes are responsible for alterations in soil properties, andtherefore, led to reduction in soil methanotrophs abundance at disturbed sites (savanna andagriculture land) compared to natural and mixed forest sites. The decreasing order of methanotrophsdensity across study ecosystems was natural forest > mixed forest > savanna > agricultural land. Theinvestigation suggested that land use changes significantly affect the soil methanotrophs abundanceand community structure in upland soils.

Ms Sweta GhoshImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bose Institute,

KolkataDesignation : Ph.D. scholar

Treatment of melanoma cancer is one of the important challenges worldwide. Although new chemotherapeutic agents and radiotherapy have improved survival and quality of patient’s life, the overall effect in the last decade has been mainly on palliation rather than reduction in mortality. Recent therapies of cancer involve the use of cytotoxic drugs, but these drugs are not very specific hence cause harm to normal cells and immunocytes resulting in severe immunosuppression. So, after apparent successful initial therapy and recovery, development of secondary tumors often leads to a relapse of the disease. This relapse not only indulges more severe neoplastic and metastatic changes, but also includes a major immune-compromised situation along with un-repairable damages of the normal cells, which ultimately lead to other cellular malfunctioning. Current therapeutic strategies include targeting the cell’s own cellular components as well as its microenvironmental niche to overcome the relapse of cancer and to induce apoptosis to cancer cell. During the past two decades, studies of sphingolipids reveal the important role of bioactive sphingolipids, such as ceramide, in regulation of multiple biological functions especially in apoptosis. Inhibiting cell death by interference on ceramide signaling is a key strategy for tumorigenesis escape from apoptotic stimuli. Therefore, for the development of cancer therapy, ceramide metabolic pathways have become a potential candidate. The anti-proliferative activities of ceramide for cancer therapy depend on the induction of various apoptotic pathways. Most of these studies are based on the exogenous administration of ceramide analogue, particularly C2- and C6-ceramides. In our study we have evaluated the exogenous short-chain C2-ceramide mediated regulation in B16F10 melanoma cells leading to tumor regression using the western blot, PCR analysis, apoptosis assays and over expression plasmid. For the first time we have showed that C2-ceramide, at a very low concentration of 20µm, induced apoptosis of the cancer cells. After screening of different families of protein kinase C on melanoma cells upon ceramide treatment, it was found that C2-ceramide up-regulated PKC? along with down-regulation of Akt. PKC? is established as one of the upstream regulators of Akt in melanoma cells. Both in vitro and in vivo study showed that PKC? has a tumor-suppressive role in melanoma cancer cell line. From the results we found, that the mentioned cellular functioning may sensitize melanoma cells towards proliferation inhibition and apoptosis. Accordingly, we can conclude that C2-ceramide may be a promising therapeutic agent for cancer treatment in future.

Dr Kalpana SengarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Kalphelix

BiotechnologiesDesignation : Director

Bleeding is the leading cause of death in almost all types of traumatic injuries in battlefield casualty and accidents. Also it has been noted that stopping hemorrhage early can prevent death in almost 90% of cases. However many trauma patients arriving late to the hospitals develops coagulopathy.Haemorrhage Control gel matrix designed to halt severe bleeding from open wounds, during injury especially in situations where tourniquets and haemostatic agents such as bandages and wound dressings are not effective. The gel is effective in sealing the edges of a wound to create a temporary hematoma that lessens blood loss before surgery. It is a polyelectrolytic gel matrix made up of tragacanth gum and alkylated mycelium chitosan and aliginate. Chitosan reacts with red blood cells which are negative charged and chitosan is positive charge so their interaction initiate hemostasis and sodium alginate bonds with wounded tissue like natural skin complex which helps in healing of wound and tragacanth cum helps in initiation of genesis of epithelium tissues for scar less fast healing Experiment was conducted to develop and evaluate combat casualty care medical product a blood loss controlling gel matrix from natural plant based polymer which help in faster healing of wound and stop bleeding in seconds saving life of trauma injury of soldiers in battlefield and accident victims. When chitosan comes into contact with red blood cells (RBCs), it can cause agglomeration. This property leads Chitosan, sodium alginate and tragacanth matrix gel to be a potential agent to form a rapid haemostatic plug to stop bleeding at wound sites.

Ms Barnini BhattacharyaImage Delegate ID Theme Details


Research


Statistical InstituteDesignation : Research

Student

In order to understand the underlying basis of a wide range of neurocognitive behavioural responsesanimals like birds, rodents and other non-human primates bearing resemblance to human mentalprocesses in terms of complexity were considered desirable model organisms. However, it was laterfound that their complex phenotypes may produce rather confusing results, leading to the difficultyin functional discrimination and prediction of cognitive processes [1]. Therefore, it was thoughtthat simpler organisms with robust, clearly distinguishable forms of behaviour may represent animproved complementary strategy to study the underlying basis of cognitive behaviour. This led tothe emergence of new animal models for neurocognitive studies, possessing behavioral simplicity andat the same time having resemblance to mammalian nervous system. Extensive research over the lastfew decades reported the utility of fish as the model animal in the field of cognitive neuroscienceand developmental biology. Until recently, fish were considered as automatons. However, now it is anestablished fact that like the rest of the vertebrate kingdom, fishes too exhibit a rich array oforganized and sophisticated behavior [2, 3]. In this backdrop, a brief review has been performed tohighlight the present rise in the use of fish as the new model animal for neurobehavioral studies.In the study, emphasis has been given on using teleost group of fish, especially zebrafish, incognitive studies. Documentation of such information may be beneficial for exploring newer animalmodels in neurocognitive research and for validation of the same through detailed experimentalfindings.

Ms Rinkal ChaudharyImage Delegate ID Theme Details


Research


University HaryanaDesignation : Research

Scholar

Forensic DNA typing and subsequent molecular methods of sex determination in humans have been provento be an imperious tool to criminal justice system. Most of the STR based commercial kits containamelogenin as the exclusive sexing marker. However, huge discrepancies have been observed withamelogenin based sex determination mostly due to X and Y deletion in the population and mutation inprimer binding sites. Though new generation STR kits have included some additional markers e.g.DYS391, DYS570, DYS576 and/or InDel to overcome this problem, each marker has their own flaws. Lackof positive control, generation of null result in case of AMELY deletion and presence ofmicrodeletions has complicated the use of aforementioned markers for sex determination. Hence,alternative sex determining markers such as STS, SRY, SNPs, DYZ1, TSPY, DXYS156 were evaluated fortheir usefulness in forensic DNA typing. Out of which Steroid Sulfatase (STS) andDXYS156 were foundto be most suitable alternative markers for sex determination.

Dr Lekha BandopadhyayImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Bose Institute

Designation : Research Scientist (DST Women

Scientist Scheme-A)

Abstract: Tiny but mighty mustard aphid Lipaphis erysimi (L.) Kaltenbach threatens the cultivationof Indian mustard Brassica juncea (L.) Czern every year. In the absence of resistant cultivars,farmers manage aphid infestation with toxic insecticides. Wild relatives of cultivated crops aspromising genetic repositories demand screening and systematic analysis. Rorippa indica (L.) Hiernis one of the recently reported potential wild crucifers showing resistance to L. erysimi. Somatichybrid raised between R. indica and B. juncea has manifested the aphid resistance trait of R.indica. When challenged with mustard aphids, cDNA–AFLP (complimentary deoxyribonucleicacid-amplified fragment length polymorphism) analysis has identified active defence response in R.indica [1]. cDNA-AFLP identified defensin and a nematode resistance protein homolog from R. indicaon over expression have shown to induce aphid tolerance in B. juncea [2, 3]. In the present study, aglobal analysis of differential gene expression was carried out within 24 hours of aphid infestationin R. indica. Paired end mRNA-sequencing (RNA-Seq) was done on aerial R. indica tissue infested anduninfested by L. erysimi. Functional annotation was done with Arabidopsis thaliana genome sequenceas reference. De novo transcriptome assembly generated 176990 unigenes. Among the identified 2723differentially expressed genes between infested and uninfested samples, majority (2083) were upregulated. While the assembled transcripts will be important to provide sequence information infurther studies, analysis of the RNA-Seq dataset was helpful to understand the defence responsecomprehensively identifying defence associated regulatory pathways. The study also gave importantinsight about biological processes involved in incompatible plant aphid interaction in a non-host.The work has implication in developing sustainable pest management measures in mustard cultivation.

Mr MONOJ SUTRADHARImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dept. of Agri.

Biotech., BCKV, MohanpurDesignation : Research

Scholar

Callus induction from mature indica rice embryo Monoj Sutradhar*, Brijesh Kumar Singh and Nirmal Mandal Department of Agricultural Biotechnology, Faculty of Agriculture, Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, Nadia-741252 Contact Author’s e-mail address: [email protected]

Abstract: The development of climate resilient high yielding rice genotypes is crucial to increase rice production. Genetic manipulation provides the most efficient way to achieve this goal in shorter period. Genetic transformation of rice is mostly done in mature seed derived callus, which is nothing but the unorganised mass of cells produced from mature embryo. The present study is focusing on standardization of popular local indica rice cultivars for callus induction. We selected few popular rice cultivars of West Bengal, namely Dudheswar, Kshitish, Pratiksha and Shatabdi for in vitro culture. The seeds were dehusked and sterilized with 70% ethanol solution for 2 min in shaker. These seeds were washed three times with sterile double distilled water and again sterilized with 5% w/v sodium hypochloride solution for 30 minutes in shaker. The seeds were again washed 5 times with sterile double distilled water. The seeds were then kept in petriplates with Whatman filter paper and dried inside laminar air flow for 15 minutes. These sterilized seeds were cultured on modified MS (MMS) medium containing (2.0, 2.5, 3.0, 3.5 and 4.0 mg/l) 2,4-dichlorophenoxyacetic acid (2,4-D), (0.25, 0.50, 1 mg/l) benzyl amino purine (BAP), 300 mg/1 casein hydrolysate, 500 mg/l Proline, 30 g/1 sucrose and 0.8% agar, pH 5.7. The freshly inoculated cultures were kept in dark condition at 25±1°C for 2 weeks and observed for callus induction. All tissue culture experiments were set up in completely randomized block design (CRD) with five replications. Data were subjected to one-way analysis of variance (ANOVA). Means were compared based on the Duncan’s multiple range test (DMRT) at p = 0.05 using the SPSS software package (Version 11, SPSS Inc. Chicago, IL). The different growth regulator combinations were found to be critical for callus induction and proliferation. The highest callus induction frequency was observed in Dudheswar (94.8 %), followed by Shatabdi (94.0 %), Kshitish (93.4 %) and Pratiksha (93.0%). The callus induction media containing 2, 4-D @ 3.0 mg/l and BAP @ 1.0 mg/l was found to be best suitable in Dudheswar and Pratiksha. The present investigation reveals that both genotypes and concentration of growth regulators significantly effect callus induction response in rice seeds.

Dr Krishan Kumar MouryaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Animal Husbandry Department

Designation : Assistant Director (SVO)

This study was carried out in non-descriptive or indigenous cattle of Go-punarwas Kendra, Hingonia, District-Jaipur, Rajasthan for determination of actual cause of death by Post-mortem examination. Approximately (1700) Post-mortem examination of cattle were performed and found that presence of Polythene bags and Foreign bodies: out of 1694 carcasses, in 1537 (90.73%) carcasses rumen was found to be packed with polybags, foreign bodies, wires, nails, pins, screws, bottle caps, leather material, rope pieces, glass pieces etc. The main cause of death in these animals is asphyxia caused by malnutrition, dehydration, heat stroke, debility, anemia, weakness and multi organ failure (liver, heart, kidney, spleen etc.). These animals show the absence of regurgitation or decreasing the food intake and their ruminal space were packed with polythene begs. Biochemical analysis of some apparently weak and debilated street cattle blood (523) were performed by using automatic biochemical analyzer (BS-200 Mindray). Serum glutamate pyruvate transaminase (SGPT) ALT, Serum Glutamic Oxaloacetic Transaminase (SGOT) AST, Glucose (GLU), Calcium (Ca), Magnesium (Mg), Phosphorus (P), Urea, Total protein (TP), Albumin and Total cholesterol were estimated. The results showed that, the variations of parameters were highly significant (p>0.05). Different level of selected macromolecules and trace elements were found in debilitated/ weak and recumbent cattle. Most of the animals were show mineral deficiency, Calcium (Ca) deficiency (96.56%); phosphorus (P) deficiency (79.73%); magnesium (Mg) deficiency (41.30%). All the cattle (94.74%) were show low glucose level; (66.73%) show low total protein level; (24.86%) show low albumin level and (21.41%) show low total cholesterol level. Higher SGPT (56.60%), SGOT (73.61%) and urea (65.97%) concentration in serum. These biochemical parameters are responsible for various body functions and deficiency of these results in impairment of functions induces structural and physiological abnormalities or mall functioning (Mcdowell, 1992). Key words: Post-mortem examination, Biochemical parameters, foreign bodies, indigenous cattle, SGPT and SGOT. Reference: 1. McDowell, LR. London, Academic. 1992, 265-293. 2. Hassan, MM.; Hoque, MA.; Islam S.; Khan, SA.; Hossain, MB.;Banu, Q. Turkish J. of Vety. Ani. Sci. 2012, 30(4): 400-408. 3. Ahmed, I.; Gohar, A.; Ahmed, N.; Ahmed, M. I. J. Agri. & Bio. 2009, 27: 83-91. 4. Osman, TEA.; AL-Busadah, KA. Pak. J. Biol. Sci. 2003, 6(14): 1253-1256. 5. Jezek, J.; Klopcic, M.; Klinkon, M. Bull. Vety. Res. Inst. in Pulawy. 2006, 50: 211-214.

Dr Srabani KarmakarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Techno India

University, West BengalDesignation : Assistant

Professor

Proteases are group of enzymes which can cleave proteins into smaller fragments and maintain homeostasis. Proteases have wide applications in biotechnology and pharmaceutical industry. Plant proteases are gaining interest due to their easy availability. Fruits and vegetables are the abundant source of commercially important proteases. The plant-derived proteolytic enzymes are finding increasing clinical and industrial applications. We could extract, purify and characterize the enzymatic activity of proteases from the leaves of Moringa oleifera. We found after structural superposition that ginger protease and papain share almost similar structure. In this study we wanted to screen the vegetables for their potential protease activity. We isolated proteases from two very common vegetable source namely ginger and onion. Protein isolation was achieved by ammonium sulfate precipitation from the aqueous extract. Proteolytic activity was studied by skim milk agar assay for qualitative detection and azocasein assay for quantitative detection. We compared the enzyme activity in different temperature, pH and different substrate concentrations. Optimum temperature for both the enzymes is 55 0C but the optimum pH for protease from ginger is 5 and the optimum pH for protease from onion is 7.5. Specific activity of the protease from onion scale leaves is lesser than ginger but the affinity is higher in case of onion protease. Another study was carried out using eleven spice seeds, namely Trachyspermum roxburghianum (Radhuni), Syzygium aromaticum (Clove), Cinnamomum verum (Cinnamon), Foeniculum vulgare (Fennel Seeds), Trachyspermum ammi (Carmom seeds), Amomum subulatum (Black Cardamom), Cuminum cyminum (Cumin seeds), Nigella sativa (Black Cumin seeds), Elettaria Cardamomum Maton (Green Cardamom), Curcuma longa (Turmeric), Coriandrum sativum (Corriander seeds). In conclusion 40% and 80% precipitated sample extract of Carmom seeds, Coriander seeds and Cumin seeds showed promising caseinolytic activity. Identification and characterization of these proteases by mass spectrometry will be interesting and valuable. New enzymes can be created with genetic manipulations after ensuring their sequences.

Mr Arpan MukherjeeImage Delegate ID Theme Details


Research


Hindu UniversityDesignation : Research

Student

Chickpea have a great economic importance as well as nutritional value among all the pulses aroundthe world. It has a high amount of proteins, vitamins, minerals etc. Different biotic and abioticfactors are responsible to decrease the production of chickpea, among them pathogens greatly affectsthe chickpea production. Chickpea seed inoculated with beneficial chickpea seed endophytic microbeshas well defined role in plant growth promotion and biotic stress management. Here we analyzed thebiocontrol activity and plant growth-promoting effects of chickpea seed endophytic bacterialstrains. The bacterial strains of Enterobacter, Bacillus, Pseudomonas, Staphylococcus, Pantoea andMixta family, were identified based on their 16S rDNA gene sequencing from the chickpea seed. Thebacterial strains show a high degree of antagonistic activity against the chickpea pathogensFusarium spp. during dual culture assays. Seed of chickpea were treated with best PGP showing seedendophytic microbes significantly increases the total biomass of root and shoot, number of leaflet,total plant length and chlorophyll status to that of non treated control plants, respectively. Themost important thing is that the root hairs of bioprimed seed are surprisingly increased as compareto untreated seed. The isolates are able to inhibit the pathogen growth as well as promote the plantgrowth by production of some important metabolites like indole-3-acetic, phosphatase, siderophores,proteases, catalase and ammonia. Conclusively seed inoculated with these Pseudomonas (chickpea seedendophytic microbes) strains potentially promotes the plant growth and induces the plant defensemechanism by increasing the synthesis of lignin and trichome in chickpea plant against Fusarium spp.challenge condition. Therefore, the use of chickpea seed endophytic microbes may also an effectivetool for replacing the chemicals fertilizer and pesticide application in near future for sustainableagriculture development.

Ms Nagma ParveenImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Kumaun

UniversityDesignation : Ph.D. Scholar

CURRENT SCENARIO OF BACTERIAL PATHOGENESIS AND ANTIMICROBIALS USED IN TRADITIONAL AND NON-TRADITION APICULTURE IN KUMAUN REGION OF UTTARAKHAND Nagma Parveen* and Satpal Singh Bisht *Ph.D. Scholar, Department of Zoology, D.S.B. Campus, Kumaun University, Nainital Professor, Department of Zoology, D.S.B. Campus, Kumaun University, Nainital Email address*: [email protected]

The present study was conceptualized to understand the status of bacterial pathogenesis and antimicrobials used in traditional and non-traditional beekeeping in Kumaun region of Uttarakhand. Honey bee colonies are mainly infected with two bacterial diseases; American Foulbrood (AFB) and European Foulbrood (EFB) disease. Antibiotics are the complex chemical substances, the secondary metabolites which are produced by microorganisms and act against other microorganisms, they may either kill or inhibit the growth of microorganism. During the survey 30 (thirty) commercial and 12 (twelve) traditional beekeepers from 17 (seventeen) study sites in rural areas of 4 (four) Districts of Kumaun region of Uttarakhand were interviewed. Amongst the interviewed commercial apiculturists 46.6% beekeepers have stopped using antibiotics as it is having hazardous impact on daily consumer’s health specially on infants but still, 53.3% apiculturists are using it along with these chemotherapeutics some herbal substances are also been used by them, while traditional beekeepers does not use any kind of antimicrobials. Key words: Beekeepers, Traditional and non-traditional, Apiculture, Bacterial pathogenesis, antimicrobials

Dr Mohamad SaleemImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : SVM

Ayurvedic Medical College ,Ilkal

Designation : PG Scholor

Introduction All Ancient Ayurvedic texts emphasizes importance of diet in growth, Stability and sustenance of all living beings. Ayurveda gives at most importance to diet in healing diseases. Aushadha yuktha ahara is essential for curing diseases. In spite of surgery, Chemotherapy and Radiation therapies evolving, the survival rate of pancreatic cancer rate is much lower in India. Second year relative survival is only 12 %. Here the study with reference of Bhavapraksha in Abyanthara vidradhi mentioned sigru (Moringa Oliefera ) soup as Ayurvedic diet for healing.

Case Report An 65 years old male visited out patient department with complains of severe abdominal pain, anorexia, weight loss, Hemtemesis, Fatigue, etc for the period not less than 9 months. Earlier he was diagnosed as Pancreatic Adeno carcinoma on 01.07.2017. Patient unwilling go any available allopathic or modern treatment that includes oral medication, Surgery, Radio & Chemotherapies

Methods & Therapeutic methodology As per the reference of Bavapraksha nigatu antra vidradhi chikitsa mentioned Ayurvedic diet with sigru (Moringa Oliefera) given daily. Morning on empty stomach- sigru decoction with Hingu and Saindava advised .Night sigru twak soup added with honey suggested to take at bed time. Morning 11 am patient was advised to take Soup with Asthi valkala ( Cissus Quadrangularis), Kohl Rabi (Brassica Oleracea), Ridge Gourd ( Luffa Acutangula ), Haidra, Ardraka, Maricha boiled and added with saindava lavana .These 3 different types of Ayurvedic Diet prescribed to the patient for 6 days in a week. For every three months end 10 days Gap was advised. Likewise these diet continued for 18 month under medical supervision. No other medication was given.

Results With first 2 weeks of the above Aushadha yuktha ahara -diet Regimen patient’s health condition improved miraculously. Encouraged with results patient advised to continue these Ayurvedic diet .Patient is Gradually recovered, Improved very well and now completely asymptomatic .His appetite improved,.The patient is now completely clinically no symptoms. He is a farmer .Nowadays he is doing all his routine farmer work without any symptoms .From the beginning itself patient is not taking any other medication except these food. He is taking regular food.

Conclusion Oncology diet is very much needed in this present era. Post chemotherapy most of the patient lose their metabolism and bio feed mechanism. As per this present study we can prove Ayurvedic Nutrition and dietetics has solution to this cancer patient managements effectively especially on GIT Pancreatic cancer.

Mr Rudradip PattanayakImage Delegate ID Theme Details


Research


CalcuttaDesignation : Senior

Research fellow

KRAS, a frequently mutated G-quadruplex forming proto-oncogene is responsible for almost each typeof cancer forming a parallel G-quadruplex structure in the promoter region. This structure is one ofthe most important drug targets for modern cancer therapy due to their unique structure andspecificity. We have screened several natural flavonoids as potential KRAS G-quadruplex stabilizingligands, using molecular modeling and docking studies. Naringin and Hesperidin evidenced highaffinity towards KRAS-promoter/G-quadruplex. As KRAS mutation is prevalent in pancreatic cancer, theefficacy of these ligands against human pancreatic ductal carcinoma cell line PANC-1 and MiaPaCa2were examined. Both the flavonoids exhibited significant cytotoxicity for the cancer cell lines butless toxicity against normal cell lines. Naringin and Hesperidin were found to induce apoptosis indose dependent manner, blocking metastasis by inhibiting epithelial to messenchymal transition,which leads to the decreased stemness for the cancer cells. The spheroid forming ability of thecancer cells and the stem cell marker’s expression were greatly decreased upon ligand treatment. In vivo studies confirmed both compounds to be effective against EAC derived solid tumors along withsignificantly low toxicity in normal Swiss albino mice. The expression of KRAS gene inligand-treated PANC-1, MiaPaCa2 and tumor-derived EAC cells were notably reduced at both protein andRNA levels. Thus, interaction of these two flavonoids with G-quadruplex DNA at the promoter regionof KRAS opens up a lot of possibilities regarding a target for anticancer therapeutic strategy.

Ms SMRITI CHOUHANImage Delegate ID Theme Details


Research


BARKATULLAH UNIVERSITY, BHOPAL


Talaromyces trachyspermus an endophytic fungi isolated from medicinal plant – A promising source of potential bioactive metabolites.

Smriti Chouhan*, Anil Prakash Department of Microbiology, Barkatullah University,Bhopal - 462026 Email- [email protected] Abstract: Talaromyces trachyspermus, a fungal endophyte isolated from leaves of Withania somnifera from Bhopal region, Madhya Pradesh was procured to examine its potential bioactive metabolites production. The antimicrobial activity of fungal extract was evaluated by using agar well diffusion method and Minimum inhibitory concentration of fungal extract were also checked against human pathogen such as Escherichia coli (BGCC 2185) and Klebsiella pneumonia (BGCC 2233). The crude ethyl acetate extract of fungus showed MIC of 2.5 ?g /ml for Escherichia coli and 5.0 ?g /ml for Klebsiella pneumonia which showed its efficacy as a potent antimicrobial. A preliminary qualitative phytochemical analysis of fungal crude extracts revealed the presence of constituents such as flavonoids, alkaloids, phenols, saponins, steroids, tannins, terpenoids in endophytic fungi. Secondary phytochemical screening was also conducted on the fungal extract using standard quantitative procedures that revealed the presence of phenols and flavonoids. Total phenolic and flavonoid content in crude extract of Talaromyces trachyspermus was 272.34 (mg/g) and 18.48 (mg/g) respectively. The isolate was also screened for extracellular biosynthesis of Silver nanoparticles for which UV-VIS absorption was recorded. FT-IR analysis was also performed to confirm the presence of various functional groups. The endophyte from Withania somnifera can be a potent natural source of bioactive compounds which can be considered to be prolific resource for drugs and as Bioprotectants. Further investigation will focus on the strain improvement and genomic variation among these isolates. Keywords: Medicinal plants, Endophytic fungi, Bioactive, Phytochemical, Antibacterial, Silver nanoparticles, FT-IR. References: 1. Devi, N.N.; John Prabakaran, J; Wahab, F. Asian Pacific Journal of Tropical Biomedicine 2012, S1280-S1284. 2. Dayma, P. B.; Mangrola, A.V.; Suriyaraj, S. P.; Dudhagara, P.; Patel, R.K. Journal of Pharmaceutical, Chemical and Biological Sciences 2019, 7(2),94-101.

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Dr Chandni TandonImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Patanjali

Research InstituteDesignation : Scientist B

Plants have received increasing attention over the past 30 years for the development of efficient and safe therapeutic drugs because of their low cytotoxic effect. Considering this, present study has been designed to determine the cytotoxicity of Dinoxin B withanolide against murine macrophage J774 cell lines. Dinoxin B withanolide was an isolated compound from ethanolic extract of Datura inoxia, which showed significant antibacterial activity. The cytotoxicity of compound was determined using MTT [3-(4, 5- dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide] assay. The compound showed significant cell viability at all the concentrations tested in comparison to control. Further, intracellular reactive oxygen species (ROS) level was performed by a fluorometric assay using 2’,7’-dichlorofluorescein diacetate (DCF-DA), which confirms the significant ROS generation in Dinoxin B withanolide. Present findings confirm the therapeutic applicability of Dinoxin B withanolide and also suggest its potent immunomodulatory activity, which may be helpful for the treatment of various infectious diseases with improved clinical and immunologic outcome. To further strengthen the potential of compound as herbal medicine, its in vivo studies are required.

Keywords: Dinoxin B withanolide, Datura inoxia, cytotoxic effect, MTT assay, ROS.

Mr MAHAMMADAMAN MALEKImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Anand Agricultural UniversityDesignation : Student

The present investigation was carried out to study the effect of micro-nutrients onmorpho-physiological, biochemical parameters and yield in black gram (Vigna mungo L.) var. GU-1 incompletely randomized block design (CRBD) with four replications. The treatments consist of control(T1), multi-micronutrient mixture (MN) grade-1 general (foliar spray) (T2), MN mixture grade-2 forZn deficiency (foliar spray) (T3), MN mixture grade-3 for Fe deficiency (foliar spray) (T4), MNmixture grade-4 for Fe and Zn deficiency (foliar spray) (T5), MN mixture grade-5 general (soilapplication) (T6) and micronutrient application as per soil test value (STV) (T7). The studyrevealed that significant improvement observed in morpho-physiological traits, biochemicalconstituents and thereby yield due to the application of micronutrients. Among the differenttreatments, multi-micronutrient mixture (MN) grade-4 (T5) treatment significantly improved themorpho-physiological parameters and thereby yield in black gram followed by the MN grade-2 (T3) andMN grade-3 (T4) as compared to control.

Ms SONAL CHAUDHARYImage Delegate ID Theme Details


Research



Scholar

Abstract: Laccase is a potential substitute for conventional chlorine based bleaching and has noreductive effect on the final yield of pulp as compared to hemi-cellulose. Pulp and paper industryis usually related to pollution issues associated with high figure BOD, COD, color, suspendedsolids, lignin and its derivatives and chlorinated compounds. The biological colour removal processuses several classes of microorganisms such as bacteria, algae and fungi to degrade the polymericlignin derived chromophoric material. Lignin is a most complex heteropolymer and does not containidentical, readily hydrolysable repeating linkages at regular intervals as in other naturalpolymers. Peroxidases and laccases are the two major classes of microbial lignin modifying enzymes.Laccases are taking centre stage of this attention, since these enzymes may help degrading lignin,using oxygen as the oxidant. Laccases is capable of eliminating the phenols through polymerizationprocess. Till date, laccases have mostly been isolated from fungi and plants, whereas laccase frombacteria has not been well studied. Bacteria seem to be more effective than fungi for thebioremediation of environmental pollutants due to their immense environmental adaptability andbiochemical versatility. It has application in pulp biobleaching, bioremediation, textile dyedecolorization, pollutant degradation, biosensors, etc. Bacterial laccases have several uniqueproperties that are not characteristics of fungal laccases such as stability at high temperature andhigh pH. Bacteria produce these enzymes either extracellularly or intracellularly and their activityis in a wide range of temperature and pH. So, bacterial isolated shows maximum laccase activity canbe more frequently studied in the field of biotechnology.

Dr Kuntal BhattacharyaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Durgapur

Government College Designation : Assistant

Professor

Integrated vector management is embattled for improving the target specificity, biocompatibility and sustainability of disease-vector control. Thus, the present study estimated the larvicidal activities of plant derived compound methyl heptadecatrieonate against the larvae of Culex quinquefasciatus (Say, 1823) under laboratory conditions. A change in larval protein content is documented after the treatment with the phyto-insecticide derived from leaves of Operculina turpethum L. Bio-active fractions were pulled out from the leaves of the novel test-plant, after initial screening, by means of three different solvents viz. petroleum ether, ethyl acetate, and methanol. Bioassays were performed against 1st to 4th instars larvae of Cx. quinquefasciatus. LC50 and LC90 values were determined through log-probit analyses. Data related to mortality was statistical justified through t-test, Tukey test and ANOVA analyses. Effects on non-target organisms were assessed. Chemical personality of the pure compound was determined by UV-Vis, infra-red spectroscopy and GC-MS analyses. Change in larval protein content was tested after 72 h of exposure. Ethyl acetate extractive was found to be the solvent extractive of choice amongst all the solvent extractives. 100% mortality was exhibited by 1st, 2nd and 3rd instars larvae. An obvious dose-dependent mortality was established through regression analyses. The non-target populations were principally non-responsive to extract and pure compound under study. Reduction of protein content by 63.13% was found after 72 h of exposure. Heptadecatrienoate was the compound responsible for killing Cx. quinquefasciatus larvae. The compound is environment friendly and largely non-toxic to non-target organisms.

Key words: phyto-insecticides, Culex quinquefasciatus, Operculina turpethum, protein metabolism

Mr Shaban AhmadImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Jamia Millia

IslamiaDesignation : Student

Abstract: Despite the nutritional excellence of rice bean, the prevailing lack of awareness of itscomplete nutritional benefits means that rice bean can be categorized as an underutilized crop. Ricebean resistance to insect and aluminium toxicity, with tremendous potential as a nutritious fodderand high-quality grain, no priority has thus far been given to understanding its floweringmechanism, palatability properties and disease resistance profiles, which are essentialcharacteristics for achieving the maximum potential of this crop. Vigna has been treated as aneconomically important genus that comprises of several domesticated species including Vigna radiata(mung bean), Vigna angularis (adzuki bean), Vigna unguiculata (cowpea) etc. Intriguingly, reportthat the ricebean VRB3 that is an under-utilized crop has been nominated for multi-location testingamongst others and ranked no.1 with an average yield of 17.08 q/ha. However, the dis-adoption ofrice bean by farmers is linked to traits of landraces like late-flowering conditions [12h/dphotoperiod] and palatable gustation to humans. Rice bean is a less well known and underutilizedlegume crop that has proved to be highly favourable due to its rich nutritional value in comparisonwith other members of the Vigna family. We have been sequenced and analyzed rice bean (Vignaumbellata) genomic resource, the size of 414 mega-base pairs with an estimate of 31276 highlyconfidential genes from 15521 scaffolds and functional coverage of 96.08% was sequenced. Rice beangenome assembly was found to be exquisitely close to V. angularis (closest), V. radiata and V.unguiculata. Further, we predicted similar discriminant results by complete CDS alignment. Incontrast, 17 medically influential genomes, when compared with rice bean assembly for LCB clustersled to the identification of more than 18000 genes from the entire selected medicinal genomes.Significantly, we found deserving late-flowering genes, palatably-indexed uncommon genes thatregulate various metabolite pathways, related to abiotic and biotic stress pathways and those thatare specific to photoperiod and disease resistance and so on. Our study produced a detaileddescription of the nutritional attributes of this legume-based on its genetic background. Theresults will increase awareness of the nutritional excellence of rice bean and improve genomicsresearch on this crop.

Mr SWARNAB SENGUPTAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NBU


Effect of nitrosative stress on metabolic flux of Saccharomyces cerevisiae

Swarnab Sengupta1*, Arindam Bhattacharjee1# * Presenting author: Department of Microbiology, University of North Bengal, Raja Rammohunpur, Siliguri, Darjeeling, West Bengal, India, pin-734013, # Corresponding author: Department of Microbiology, University of North Bengal, Raja Rammohunpur, Siliguri, Darjeeling, West Bengal, India, pin-734013 [email protected]

Abstract `Nitrosative stress' involves reactive nitrogen species (RNS) where the ratio of nitrosants to antioxidants is >1. Reactive nitrogen species or RNS (e.g. peroxynitrite, nitric oxide radicals, nitrogen dioxide radicals) at higher concentrations causes alternation of several biochemical processes inside the cell. In this study, we have characterized the effect of RNS on the metabolic pathways of Saccharomyces cerevisiae, an industrially important organism known for its ability to produce ethanol. Thus, it is very important to characterize the metabolic pathway under nitrosative stress. Here, we are reporting for the first time the effect of nitrosative stress on ethanol production. An increase in alcohol production by 35% and 1.34-fold increase in specific activity of alcohol dehydrogenase have been detected under stress condition compared to the control. Under nitrosative stress the specific activity of Aconitase, a key respiratory enzyme has been decreased by 55% because of nitration of the enzyme. The molecular docking study also supports the possibility of Aconitase nitrification. Under nitrosative stress, we have also found changes in the activity of some important enzymes in energy producing pathway e.g., Citrate lyases, Malic dehydrogenase (decarboxylating), Aldehyde dehydrogenase etc. We assume that under nitrosative stress pyruvate may be regenerated from malate and which in turn gets into the alcohol fermentation, thus diverting their metabolic flux towards alcohol production. References: Kang JW, Lee NY, Cho KC, Lee MY, Choi DY, et al. Analysis of nitrated proteins in Saccharomyces cerevisiae involved in mating signal transduction. Proteomics, 2015, 15: 580-90. Bhattacharjee A, Majumdar U, Maity D, Sarkar TS, Goswami AM, et al. In vivo protein tyrosine nitration in S. cerevisiae: identification of tyrosinenitrated proteins in mitochondria. Biochem Biophys Res Commun, 2009, 388: 612-7.

Mr Rohan NathImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : North Bengal


Scholar

Effect of nitrosative stress on meiosis of Schizosaccharomyces pombe

*Rohan Nath, Dr. Arindam Bhattacharjee

Department of Microbiology, University of North Bengal, Raja Rammohanpur, Shivmandir, Dist- Darjeeling, West Bengal, India, Pin- 734013

Abstract: Nitrosative stress is the hostile condition which is faced by a cell when the modification of macromolecules is challenged by Reactive nitrogen species (RNS). Free NO. radical reacts with Reactive oxygen species (ROS) to form RNS and this RNS mainly mediates the nitrosative stress. The physicochemical properties are also changed during the nitrosative stress. Most of the research with cell cycle in nitrosative stress biology is mainly focused on mitosis but we don’t know exactly what happens in a cell undergoing meiosis. Meiosis is a very important process in gametes, a single mutation or alteration in the gene expression can be fatal. There are reports which show gamete & embryos are heavily affected due to either absence or overproduction of RNS. Hence, information regarding the adverse condition such as nitrosative stress through which a gamete might undergo is very crucial. The aim of this study is to characterize the effects of nitrosative stress in a cell undergoing meiosis and identify the mechanism by which the meiotic cells are overcoming this stressful condition. We have selected Schizosaccharomyces pombe as the most preferable microorganism as it has huge genetic similarity with mammals especially humans; most of the genes for cell division and cellular organisation in fission yeast are also found in humans. Preliminary experiments are done with S. pombe wild type strains where the effects of nitrating agents at sub-toxic doses are observed. Meiotic gene expression gets effected but the mechanism by which they’re upregulated or downregulated is yet to be known. Formation of reactive oxygen species and reactive nitrogen species will be checked with fluorescent dyes in fluorescence microscope. Further experiments will carried out with mutant strains which will give us a more elaborate idea of their survival pathway under nitrosative stress conditions.

Ms APARNA SHILImage Delegate ID Theme Details


Research


Life sciences, Presidency University


Background: Human skin is natural habitat of different kinds of normal flora including Staphylococcus aureus (S. aureus). According to present scenario, community associated strains of S.aureus are exhibiting resistance against commonly used antibiotics. Therapeutic challenges has already been generated in combating infections caused by multiple antibiotic resistant S.aureus. Aim of study: This study focuses on to evaluate the prevalence of multiple antibiotic resistant strains of S. aureus in community and effect of Catharanthus roseus extract on them as antibacterial agent. Methods: Antibiotic susceptibility pattern of strains were determined by disk diffusion method. Agar well diffusion(1) was used to determined the antibacterial efficacy of C. roseus extract. Then MIC values (1) and fractional inhibitory concentrations , kill kinetics of extract were also examined. Electron microscopic images of bacterial cells have also been taken to examine the morphological changes in presence of extract. Results: The study reveals that 80% community associated S. aureus colonizes in nasal cavity and more than 90% of it are resistant to ampicillin and methicillin, 46% are multiple antibiotic resistant strains. The result obtained by determining MIC, MBC, growth pattern and SEM image indicates that ethanolic root extract of C. roseus has most significant antibacterial effect on S. aureus. More results clearly indicate that ethanolic root extract of C. roseus also gives a synergistic effect on antibiotic at a concentration lower than its MIC value. Conclusion: The high occurrence of multiple antibiotic resistant strains in community is an alarming sign for the world of therapy, escalating the mortality rate due to uncontrolled infectious disease. Effective herbal extract like C. roseus can be as an alternative therapeutic agent instead of conventional antibiotics.

Dr Rakkimuthu RamalingamImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Nallamuthu

Gounder Mahalingam CollegeDesignation : Assistant

professor and Head , PG and Research Department of

Botany

Aim: In this present study a green, low-cost and reproducible Anisomeles malabarica leaves mediated synthesis of Ag-rGO is reported.

Backround: Graphene is a two dimensional material which has received an extensive attention due to its high surface area, excellent electrical and thermal properties, extended charge carrier mobility. Graphene oxide (GO) is considered as a precursor of graphene which is composed of nearly flat rigid of carbon atoms in which oxygen containing groups are covalently linked [1]. Due to large surface area GO which can be used to decorate metal nanoparticles like silver.

Materials & Methods: In this paper we develop a rapid preparation of graphene from graphite using modified Hummers method [2] and reduced by A. malabarica leaf extract. The prepared rGO is dispersed with AgNO3 and extract by ultrasonication and the resultant solution was transferred to Teflon coated silica crucible and kept in an oven for 10min at 80? C. The synthesized GO and rGO–Ag nanocomposite was characterized by using UV-Vis spectroscopy and FT-IR. The antibacterial properties of the synthesized GO and rGo-Ag nanocomposite were evaluated against human pathogenic organisms like Escherichia coli (MTCC77), Pseudomonas aeruginosa (MTCC 424), Klebsiella pneumoniae (MTCC 3384), Staphylococcus aureus (MTCC 96) using agar well diffusion method.

Results & Discussion: The synthesized GO showed the maximum zone of inhibition against Staphylococcus aureus (26 mm) and rGO-Ag nanocomposite showed the maximum zone of inhibition against Pseudomonas aeruginosa (28 mm) at 50 µl concentrations. The nanocomposites were effective antibacterial agents against both gram positive and gram negative bacteria. The photocatalytic performance of rGO for the degradation of methylene blue under visible light was carried out. It exhibited 74% for the degradation of Methlene blue, whereas Ag-rGO nano composites showed 92%. From the results as prepared silver nanoparticles reduce graphene nanocomposites are behave a very good antibacterial agent as well as good photocatalyst.

References: 1. Chen, D.; Feng, H.; . Li, J. J.Chem. Rev. 2012, 112, 6027-6053. 2. Marcano, D.C.; Kosynkin, D.V.; Berlin, J.B; ACS Nano. 2010, 4, 4806-4814.

Ms Monika Yashpal SajwanImage Delegate ID Theme Details


Research


G.B.Pant.University of Agriculture & Technology


Medicinal plants are Nature’s gift to help pursue a disease free healthy life, and thus can playan important role in preserving health. Studies on elicitation response of phytochemicalconstituents such as phenols, tannins, flavonoids, alkaloids, amino acids, terpenes etc., in theleaves of Artemisia annua cv. SIM AROGYA (medicinal plant) grown in different type of organicmanures - Farm Yard manure (FYM), Vermicompost and Poultry Manure was undertaken. The experimentwere conducted at the experimental field of MRDC, GBPUA&T, Pantnagar using Randomised Block Design.There is a remarkable influence of organic manures on soil characteristic and morphologicalcharacteristics of plants such as number of branches, shoot length, stem diameter and phytochemicalconstituents. Further qualitative and quantitative analysis of phytochemical constituents and theresultant antioxidant capacity of the secondary metabolites in the plant extract are carried out.The powdered aerial parts were extracted with n- hexane, aqua ethanol, and di-ethyl ether. The n-hexane gave the highest yield, followed by aqua ethanol and di ehyle ether. Organic manures (FYM,vermicompost and poultry) are also affect the presence of phytochemical constituients. All theparameters are compared to chemical fertilizer and control.

Mr Rajagopal GopalanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Ayya Nadar

Janaki Ammal CollegeDesignation : Research

Scholar

Aedes aegypti is the primary vector transmits so many lethal diseases ( Dengue, yellow fever, Zika)to human being. Since there is no effective way to complete eradicate the Aedes mosquito populationsin the world. Recently, mosquito control program focused on eco-friendly approach using symbioticrelationship of microorganism is an effective tool to reduce vector competence. In the present studywas undertaken to the capable bacterial strains isolated in infected Lepidoptera larvae andcollected from agriculture fields of the Western Ghats, Srivilliputtur range, Tamil Nadu. Theisolated bacterial strains preliminarily screened against earily 3rd instar of A. aegypti larvae.From which pigmented rod-shaped gram-negative bacterial (SBF13) strain was higher activity thanother bacterial strains. DNA was isolated from higher activity strain (SBF13), and DNA was amplifiedin PCR using universal primer and sequenced result conformed to BLASTn as SBF13- Serratianematodiphila (MK791595). The cell mass of S. nematodiphila (SBF13) strain was further screenedusing lethal, and sublethal concentration against early 3rd instar of A. aegypti andhistopathological studies was carried and find out the change midgut microbiota then discover thedegradation of protein in experimental A.aegypti larvae. From our observations, Serratianematodiphila strain was interfering the larval developmental durations.It shows the LC50 in 24 and48 hours as follows 5.43µg/ml and 2.86µg/ml and bacteria injury to hydrofuge hairs, respiratorytract, gills and siphon in A. aegypti larvae. In particular, the infection causes overgrowth andtranslocation of the opportunistic pathogen thus promote mosquito larvae death. Our study may leadto a new strategy for biological control of mosquitoes.

Mr Sourav KumarImage Delegate ID Theme Details


Research


UniversityDesignation : Doctoral

Research Fellow

Background: Amyloid beta-peptide (Abeta) has been implicated in the pathogenesis of Alzheimer’s disease (AD). Specific neuropathological changes involved in the formation of the extracellular amyloid plaques and intracellular neurofibrillary tangles. This Abeta can cause cell death in AD by evoking a cascade of oxidative damage to neurons, with an ultimate effect of apoptotic neurodegeneration. Objective: This study was aimed to investigate the neuroprotective effect of Bacopa monnieri (BM) in amyloid-beta (Abeta1–40) induced neurodegenerative changes in SH-SY5Y neuroblastoma cells. Methods: SH-SY5Y cells were treated with Abeta1–40 (10microM) to induce neurotoxicity. Bacopa monnieri (50µg/ml) was incubated with SH-SY5Y cells to protect against Abeta-induced neurodegeneration. Assay for cell viability, mitochondrial membrane potential (MMP), intracellular free Ca2+ and apoptotic cells was performed in vitro. Western blot analyses were performed for the estimation of key apoptotic and AD biomarker proteins. Results: Our results showed that Abeta1-40 treatment reduced cell viability, disturbed the MMP and Ca2+ homeostasis in SH-SY5Y cells and increased neuronal apoptosis. Treatment with Bacopa monnieri for 24h retained the cell viability, normalized ?m, and Ca2+ level, and decreased the neuronal cell death. In accordance, Bacopa monnieri reversed Abeta-induced effect on protein expression of mitochondrial apoptotic pathway (Bax, cytochrome C, caspase-9 and caspase-3) and major Alzheimer’s markers i.e. Abeta, APP, P-tau, and BACE-1. Conclusion: Overall, our results showed that Bacopa monnieri are potential candidates to treat neurodegenerative disorders like AD. 1. Kumar, S., Paul, A., Kalita, S., Ghosh, A. K., Mandal, B., & Mondal, A. C. Chem Biol Drug Des. 2017, 89(6):888-900

Dr Akhilesh Kumar PandeyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Institute of Sciences, Banaras Hindu

UniversityDesignation : Reseasch

scholar

In plants, arsenic (As) stress modulates metabolic cascades at various developmental stages byinfluencing the pattern of gene expressions mediated by small non-coding RNAs specially Micro-RNAs.Micro-RNAs (miRNA) are small (21–24 ntds) non-coding RNAs, involved in the moderation of a myriadof cellular processes needed for plant adaptation upon oxidative stresses. miR156j belongs to miR156gene family, which is highly conserved and are involved mainly in the regulation of growth anddevelopment in plants. In order to better understand the functional role of miRNA156j in rice atdifferent developmental stages (seedlings, tillering & flowering), we analyzed the expression invarious tissues (leaf, stem & root tissues) under “As” stress. Additionally, usingBioinformatics tools, target genes of miRNA156j and the potential co-expressed genes were exploredat different development stages in various tissues in rice under stress condition. Expression ofmiRNA156j was analyzed by qPCR and Northern blotting which unveiled its temporal down regulation invarious plant tissues in various developmental stages. Of note, the down regulation was morepronounced in root tissues at seedlings, tillering and flowering stages during 0-72 hours under As(III) treatment. Overall, As stress altered the gene expression more prominently at seedlingsdevelopmental stage followed by flowering and tillering. The most pertinent targets identified wereDNA binding transcription factors, DNA binding proteins, acetyltransferases, phospholipase A1 andteosinte glume architecture 1. The results of the current study demonstrate the prominent role ofOsa-miRNA156j in As (III) stress which was found to modulate the metabolic activities in rice plantsat different developmental stages

Mr Purvaj BaroteImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dr.D.Y.Patil Institute Of pharmaceutical

Science and research pimpri, pune


Abstract: Background: The administration of two or more drugs may leads to drug-drug interaction. The term drug interaction is defined as an alteration in duration or magnitude of the pharmacological effect of one drug produced by another drug. And in the treatment of tuberculosis in which multiple drug therapy are used, chances of drug interactions increased. The anti-microbial resistances are also increased with the use of antibacterial or antitubercular drugs in combination. Objectives: Evaluation of Pharmacodynamic interaction between Curcumin and antitubecular drugs (Rifampicin and Isoniazid) in Wistar Rats. Material and Method: The study aims towards the evaluation of antimicrobial activity of combination of Curcumin with selected antitubercular drugs against E.coli and S.aureus. Evaluation of antitubercular activity of Phytoconstituents against Mycobacterium tuberculosis was done by Alamar Blue Assay. To carry out the compatibility studies of combination of Curcumin with selected antitubercular drugs. The evaluation of hepatoprotective activity of Curcumin against hepatotoxicity induced by selected antitubercular drugs (rifampicin and isoniazid). Result: Rf value of combination of Curcumin with rifampicin and isoniazid does not show any incompatibility when compared with single drug. Zone of inhibition study showed synergistic effect of Curcumin with rifampicin & isoniazid against S.aureus and E.coli. In-vitro antitubercular study of rifampicin showed activity at all concentration, while isoniazid at 50µg/ml and Curcumin at 163µg/ml while co-administration of Curcumin with rifampicin & isoniazid for 28 days treatment showed significant increase in body weight , level of total protein while significant decreased in serum transaminase, alkaline phosphatases and total bilirubin. Conclusion: The combination of Curcumin and antitubercular drugs does not show any physical interaction which might not affect the absorption of drug. Combination of drug showed antibacterial activity evaluated by zone of inhibition. Phytoconstituents showed anti-tubercular activity at different concentration. The hepatoprotective action of Curcumin was concluded by Evaluation of liver parameter and body weight. From the histopathological reports of liver, it was concluded that the herbal mixture improves hepatocellular vacuolation and infiltration of inflammatory cells. Keywords: Curcumin, hepatoprotective, zone of inhibiton, anti-tubecular activity. Referance: 1. Kim M, Hynicka LM. “Azithromycin-induced hepatotoxicity”. Hospital Pharmacy.2012 Dec; 47(12):946-9.

Mr Amartya PradhanImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Georgia State University, Atlanta, Georgia -

30303, USADesignation : Research

Affiliate

Cancer aggressiveness is linked to the accumulation of lipid droplets (LD) inside the cells. LDs aredynamic organelles involved in critical cellular processes viz. lipid storage and metabolism, energyproduction, gene regulation, and signal transduction. Hence, cancer cells harness LDs to theiradvantage. The association of LD with poor prognosis in cancers has been widely documented, andtriple-negative breast cancer (TNBC), an aggressive subtype of breast cancer is no exception tothat. TNBC lacks key hormone receptors, including estrogen receptor, progesterone receptor, and afunctional human epidermal growth factor receptor 2 (HER2). Due to the absence/underexpression ofthese key receptors, TNBC is refractory to the conventional treatment regimens, and thus, there is adire unmet need to evaluate novel therapeutic targets to improve its prognosis. Owing to the role ofLDs in cancer cell proliferation and chemoresistance, we hypothesized that LD accumulation iscrucial for TNBC survival under drug-induced stress, under which a non-cancerous cell would undergoapoptosis. Hence, LDs could serve as a viable target for improving TNBC prognosis. The primary focusof this study was to determine whether drug-induced stress could alter LD density in TNBC. Here, weinitially standardized the staining conditions for LDs in TNBC cell lines using Oil Red O, a dyethat stains LDs and hematoxylin, a counterstain mainly staining the nucleus. The standardizedprotocol that we established for various TNBC cell lines could serve as a foundation to carry out LDrelated experiments in TNBC cell line model. Further, to understand the role of stress induced bycommon chemotherapeutic drugs used against TNBC in altering LD density, we treated TNBC cell linesviz. MDA-MB-231, MDA-MB-468, and HCC1806, with differing concentrations of doxorubicin, the firstline of treatment in TNBC. LD density was compared in untreated control, and doxorubicin treatedTNBC cell lines. The LD area was analyzed using ImageJ software, and Student’s t-test wasperformed to determine the difference in LD area in treated versus non-treated TNBC cell linesamples. We observed a significant increase (p?0.0005) in LD area after doxorubicin treatmentcompared to untreated control samples. Hence, this increase in LD area may attribute to the LDmediated chemoresistance, suggesting an urgent need to improve our understanding of employing LD asa therapeutic target. Inclusion of panel of other chemotherapeutic drugs and checking theireffectiveness in context of LD density are currently underway in our lab.

Ms TARUNA PANDEYImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-CIMAP

LUCKNOWDesignation : CSIR-JRF

Alzheimer’s disease (AD) is a major progressive neurodegenerative which is orchestrated by cognitive decline due loss of acetylcholine (Ach) levels and amyloid beta aggregation. Ach deficiency is the main event underlying the pathophysiology of the AD symptomatology. Plaques containing amyloid beta aggregations have been observed in brain of AD patients and various studies report the relation between these amyloid beta deposits and depleted Ach levels(Schelterns and Feldman,2003). The current regimen for AD treatment employs use of acetylcholinesterase (Ache) inhibitors like galantamine and donepezil(Dineley, 2007). Reactive oxygen species (ROS) plays a pivotal role in initiating and aggravating the neuronal loss associated with AD. Therefore, we explored the effect of swertiamarin, a secoiridoid glycoside isolated from Enicostemma littorale Blume (Family-Gentianaceae) for its anti-oxidant promoting and anti-Alzheimer’s activities using Caenorhabditis elegans model system. Our results illustrated that SW treatment significantly enhanced the paraquat induced oxidative stress tolerance in worms. In agreement with the ameliorated ROS levels detected through DCF-DA method, SW treatment led to up regulated mRNA expression of antioxidant and phase II detoxification genes viz. sod-3 and gst-4 respectively. SW enhanced synaptic acetylcholine levels in both wild type (N2) and diseased worm (CL2006 strain with amyloid beta) as proved from increased aldicarb induced paralysis in worms. A decreased Ache levels in worms (N2 and CL2006) was observed using Amplex Red Ache detection kit(Thermo Fisher). Altogether, our data suggest that SW enhanced Ach levels, mitigated ROS levels and Ache levels in C. elegans. Our studies propose SW as a potential molecule for its properties against ageing and Alzheimer’s disease. References Schelterns, P., & Feldman, H. (2003). Treatment of Alzheimer's disease; current status and new perspectives. The Lancet Neurology, 2(9), 539-547. Dineley, K. T. (2007). Beta-amyloid peptide--nicotinic acetylcholine receptor interaction: the two faces of health and disease. Frontiers in bioscience: a journal and virtual library, 12, 5030-5038

Mr Rezwanuzzaman LaskarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dept. Of

Biological Sciences, Aliah University


In-silico extraction of microsatellite which has great role in genetics and evolutionary biology, isan economical than conventional investigational method. Microsatellites or SSRs are highly variable1-6 nucleotides tandemly genomewide repeats. Betapolyomavirus, the genus of the familyPolyomaviridae, containing the well-studied human polyomaviruses(BK and JC polyomavirus) isresponsible mainly for producing tumors, kidney related diseases and brain white matter diseases inmammals. This paper focuses on elicitation and investigation of microsatellite from whole genomesequence(WGS) of 30 species of betapolyomavirus. The WGSs were accessed from web-baseddatabase(NCBI) and microsatellite mining was conducted through a SSR extractor tool (IMEx). Theaverage genome length of all studied viruses were 5.13 kb and their Guanine Cytosine content rangedfrom 44.64% found in BM47 to 37.64% in BM68. Among the 158926 bp analyzed sequence, we extractedtotal 1029 SSRs, of which BM65 exhibited highest simple sequence repeats i.e. 47 and 19 was lowestin BM59. The RA of SSR ranged from 9.32(BM65) to 3.80(BM59). The RD of SSR ranged from 80.34(BM65)to 27.97(BM59). The regression analysis of SSR showed a non-significant correlation with GC%.However, SSR incidence was significantly correlated with genome size, relative abundance andrelative density. The maximum R squared value was high in sRA with SSR followed by sRD, GC% andgenome size. We found that the distribution of SSRs are random across the genome and heterogeneityof SSR incidence indicate the high level of variability among the member of betapolyomavirus.

Mr SHUBHAM MUSALEImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : pharmacy

Designation : student

ABSTRACT Polymer and cross linking agent affects drug release of microsphere. Nifedipine microspheres were prepared using Ionotropic gelation technique, varying polymer and crosslinking agent concentration and keeping concentration of Nifedipine and sodium alginate, temperature and rpm constant. Various ratios of drug: polymer (Hydroxy propyl methylcellulose, Eethylcellulose, Eudragit) (1:1, 1:2, 1:3 w/w), and cross linking agent (4%, 5%, 6% w/v) were studied. Aim of study is to examine effects of this parameter on the particle size, percentage yield, entrapment efficiency and in-vitro release of Nifedipine microspheres. Eethylcellulose, Hydroxy propyl methylcellulose and Eudragit microsphere show Percent entrapment in range of 78.43-88.92%, 81.44-91.96%, 87.15-94.67% and drug release 76.36-92%, 75.08-94.59%, 84.15-95.89% respectively. EU-6 batch were found to be optimizing in terms of percent yield (91.89%), percent entrapment (93.04%) and in-vitro release (95.89%). Optimized formulations were subjected to scanning electron microscopy, FTIR and accelerated stability study. The smooth surface of microspheres as seen by SEM due to complete homogeneity of drug and polymers. FTIR study shows there was no incompatibility seen in between drug and polymer used. Accelerated stability study was carried out at 40 ± 20C/75 ± 5 % RH condition for a month and found to retain their stability with respect to drug entrapment and drug release. Thus, the variation in polymer/cross linking agent ratios have an influence on the physical characteristics of the microspheres and increase in polymer and crosslinking agent concentration causes a decrease drug release by increasing the crosslink density thereby creating barrier for drug diffusion. KEYWORDS: Crosslinking Agent, Microspheres, Nifedipine, Ionotropic Gelation.

Ms AKANKSHA YADAVImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : PT. J.N.M.

MEDICAL COLLEGE RAIPURDesignation : STUDENT

Study of oxidative stress in vitiligo Akanksha Yadav 1 , Jagannath pal 2, Yogita Rajput3 1- student, Dept. of Biochemistry, 2-scientist-1, Dept. of Biochemistry, 3- scientist 2, Deprt. of biochemistry, J.N.M. Medical College Raipur (C.G.)

Abstract VITILIGO is idiopathic disorder characterized by macular hypopigmentation due to melanocyte impairment and absence of melanin prodution. there is an antioxidant-prooxidant ratio shift involved in oxidative stress. Malondialdehyde (MDA) is a stable the product of lipid peroxidation and is a biological marker of the increased oxitative stress. so the aim is to determine the correlation between oxidative stress with vitiligo severity. Venous blood samples were collected for estimation of MDA which is considerd as marker for oxidative stress in the blood of 40 patients of vitiligo. detailed history was taken ad clinical assessment of vitiligo was done. the mean value of MDA in our patients were 4.3 to 2.7Du/ml. as compared to controls, increeased MDA level were suggestive of oxidative stess in patients of vitiligo in our study. more studies of relative larger sample size are required to further confirm these variation of MDA in the blood.

Mr Pratik ParmarImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Anand Agricultural University

Designation : M.Sc (Agri.) Agronomy

India is an agricultural country. Every year about 841 MT crop residues are produced in Indianagriculture and nearly 100 MT is burned. According to Crop Residue management report of IARI (Anon.2012) the residue generation is highest in UP (60 MT) followed by Punjab (51 MT) and Maharashtra (46MT). Residue burning becomes severe problem when large parts of northern India choke on smog andhaze triggered by large scale crop residue burning. It results in GHG’s emissions from open fieldswhich cause air pollution. Now a day’s management of ‘Farm Crop Residues’ is important as itis highly considered as major factor in ‘Organic’ and ‘Conservation’ agriculture. Thedifferent practices of its recycling, mulching, in-situ incorporation and composting areeco-friendly. Sometimes it takes time if proper environment for recycling is not available. Residerecycling is needed to maintain an acceptable environment free from excessive pollution on groundand in air, amelioration of soil acidity through the release of hydroxyls especially during thedecomposition of residues with higher C: N ratio, correction of soil alkalinity by application ofresidues of lower C: N ratio crops including legumes, oilseeds and pulses and to improve soilhealth. Soil physic-chemical and biological properties decide the rate of microbial activity in caseof in-situ incorporation while in composting its affected by the environment and type of microbialdecomposers. Therefore, a favorable environment for microbial activity is necessary which is veryimportant for microbial decomposition of crop residues. Which conserve our environment ineco-friendly way and recycling resulted in extra beneficial outcome.

Ms Rajni SharmaImage Delegate ID Theme Details


Research


Institute of Medical Sciences Lucknow

Designation : PhD student (SRF)

Background: Diabetic nephropathy is one of the severe complication of diabetes that affects population worldwide. Early diagnosis of disease onset and /or progression would help its clinical management. Here we established the usefulness of Wilms’ tumor 1 (WT1) , a podocyte specific marker and a transcription factor, as a potential predictor of kidney disease in diabetes.

Method : To identify the potential predictor of early kidney disease proteomic profiling of UE from T1D with or without albuminuria (urine albumin to creatinine ratio between 30–300 mg/g, n=3/group) was performed using two dimensional differential gel electrophoresis (2D-DIGE). Validation for presence of WT-1 protein in UE was done by ELISA in early kidney disease subjects and by western blotting in T1D subjects without albuminuria. Lastly, to examine the diagnostic potential of WT-1 protein in UE as an early predictor of kidney disease 29 WT-1 expressing T1D subjects without albuminuria were followed for ~ 4.5 years (study-2). Urine microalbumin, serum creatinine and HbA1C were analyzed.

Result : Proteomic profiling by 2D-DIGE revealed a total number of 592 differential protein spots between T1D subjects with or without albuminuria. The MASCOT search for 26 selected spots revealed 14 proteins associated with nephropathy, including Wilms' Tumor 1 (WT1) protein. Quantitative estimation by ELISA showed increased levels of WT-1 in kidney disease subjects relative to controls. At the end of 4.5 years of follow up, 9 subjects (out of total 19) progressed to albuminria in WT1-positive group (presence of WT-1 in UE at the time of recruitment) as opposed to 1 in WT1 negative group. Both groups had statistically similar diabetes duration, age, % HbA1c and estimated GFR at the baseline.

Conclusion :WT-1 in urinary exosomes could predict a risk of developing kidney disease in diabetes. Funded by intramural, DST, govt of India.

References : Zhou H, Cheruvanky A, Hu X, Matsumoto T, Hiramatsu N, et al. (2008) Kidney Int 74: 613–621.

Mr Shahnawaz SameemImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sam

Higginbottom University of Agriculture Technology and

sciencesDesignation : Research

Scholar

Hepatic carcinoma is widely known, and prominent carcinoma around the globe and remain asymptomaticdiseases. Ziziphus mauritiana possess anti-proliferative, antioxidant, hepatoprotective property andused in hepatic cancer. The recent study deals to evaluate the chemoprotective and therapeuticproperty of Ziziphus mauritiana embedded silver nanoparticles (AgNPs) against diethylnitrosamine(DEN) -induced hepatic cancer. Novel approach for biofabrication of Silver nanoparticles usingaqueous extract is a highly relevant and recent in nanotechnological research. Biofabricated AgNPshave better hepatoprotective effects compared to aqueous extract and silver nitrate.Characterization shows biofabrication of silver nanoparticles (AgNPs). The particles werecharacterized using UV Visible spectroscopy, SEM, XRD, FT-IR.

Mr saras tiwariImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Dr. D Y patil institute of pharmaceutical

sciences and research Designation : student

Abstract: Achyranthes aspera Linn. (family- Amaranthaceae) is very well known plant, mainly found in India, in almost every region. It is known as Latjira in Hindi and Aghada in Marathi. The various parts of plant have several medicinal properties and are useful in dysentery, fever, diabetes, bronchitis, heart maladies, piles, itching, abdominal problems etc. The roots of A. aspera Linn are traditionally used in Uttar Pradesh, India for induction of labor in pregnant woman, but the method of induction is very crude, as it involves tying of root to thigh or womb or drinking root extract of the plant. The roots are reported /found to contain alkaloids, flavonoids, saponins, glycosides, steroids and terpenoids. Literature survey revealed that the effect of root extract has been studied in pregnant rat to assess the labor and parturition pattern. It has also been used to increase the animal fertility. Although the exact mechanism behind these activities are unknown till date. The hypothesis was made on basis of contractile property of oxytocin hormone during labor which is responsible for easy delivery. The root extract of the plant may be expected to have similar effect on uterine muscle since it also induces labor. But no reports have been found, indicating this effect on isolated uterine contraction in animals. The aim and objective of present study was to evaluate uterine contractile property of aqueous extract of root of A. aspera Linn. ex-vivo on isolated chicken uterus preparation and its antagonism by some selective antagonists for mechanistic study. The aqueous extract of roots of A. aspera Linn shows contraction of isolated chicken uterus. The traditional use of these roots for induction of labor and ease of delivery can be attributed to increased uterine contraction. As the contraction was antagonized by muscarinic antagonist atropine, it may involve the muscarinic receptor mechanism.

Dr Jnanendra RathImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Visva-Bharati

(A Central University)Designation : Assistant

Professor

Ultraviolet-A constitutes 95% of the total UV radiation in the sunlight, can impair biologicalprocesses and can cause skin cancer. Lyngbya aestuarii a marine cyanobacterium isolated from Chilikalagoon, which floats in the brackish waters of Chilika exposed to 1.8 to 2.6 mW/cm2 UV-Airradiation. With response to UV-A irradiation, it biosynthesizes a novel alkaloid scytonemin withmaximum biosynthesis with 60 h of UV-A irradiation. Besides the increase in carotenoids, SOD andcatalase enzyme activity were observed up to 60h and 48h of UV-A irradiation. Cellular carbohydratecontent of L. aestuarii increased up to 12h of UV-A irradiation however, the cellular protein wasnot much affected by UV?A irradiation. P38 mitogen-activated protein kinases are linked toinflammatory disorders and can respond to stress stimuli such as ultraviolet irradiation, heat shockand are involved in cell differentiation and apoptosis. Molecular docking studies show scytonemin ishaving vital interactions and binding confirmation with the active site of the p38 kinase and caninhibit p38 kinase activity. P38 MAPK inhibitors have recently been claimed as novel and potentialtherapeutics for neurodegenerative diseases, a type of chronic inflammatory disease and in thisregard scytonemin of marine cyanobacterium Lyngbya aestuarii is having great potential

Dr Sikha MandalImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sree

Chaitanya CollegeDesignation : Assistant

Professor

Infectious diseases were the leading cause of death worldwide and emerging infectious diseases(EIDs) are a significant burden on global economies and public health. Complex carbohydrates are thenext frontier in understanding the secret molecular messages that rule the life of our cells.Cyanobacteria in general and extremophilic cyanobacteria, in particular, are one of the richestsources of complex polysaccharides. We have isolated 20 cyanobacteria from extreme habitats of Indiaand out of them 5 cyanobacteria is having good amount of CPS (Capsular polysaccharides) and RPS(Released polysaccharides). Glycoconjugate vaccines elicit a T cell response that boosts theproduction of high-affinity antibodies against the polysaccharide by B cells. Therefore vaccines canbe prepared from the bioactive glycans of these cyanobacteria. Glycans of cyanobacteria arewater-soluble. Hence, attaching a glycosidic moiety into a target drug molecule increases itshydrophilicity. This influences tremendously the pharmacokinetic properties of the compound, i.e.circulation, elimination, and concentrations in the body fluids. In this context, glycans ofcyanobacteria are having a tremendous therapeutic value which will be presented.

Dr AMITA BARIKImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NIT Durgapur


Protein-RNA interactions play a vital role in most of the cellular processes. Here, we present acomputational analysis to understand the structural basis of the specificity of protein-RNArecognition. The interactions between protein and RNA subunits in 160 protein-RNA complexes curatedfrom the Protein Data Bank is studied and the outcomes are compared with protein-protein andprotein-DNA interactions. The geometric, structural and physicochemical properties of protein-RNAinterfaces reveal that the RNA contributes more to the interface area than its partner protein. Theaverage protein-RNA interface is found to be smaller than the average protein-DNA interface butlarger than the average protein-protein interface. The RNA side is well packed, and is recognized bythe strong positive electrostatic potential of the protein. An average protein-RNA interface is lesshydrated than an average protein-DNA interface, but more hydrated than an average protein-proteininterface. This is reflected by the density of interface waters as well as the density of direct andwater-mediated H-bonds. In contrast to protein-DNA interfaces, mainly due to the presence of the2'-OH in RNA, the ribose is more hydrated than the phosphate and the bases in protein-RNAinterfaces. In contrast to protein-DNA interfaces, the minor grove in protein-RNA interfaces ishydrated more than the major groove. About 21% of the interface waters remain preserved uponcomplexation, and they make higher number of H-bonds compared to the other interface waters. Theevolutionary study shows the residues at the interface core are the most preserved, and the surfaceresidues are the least. Conformational analysis with bound and unbound structures shows the RNA isgenerally more flexible than the protein, and the interface region is as flexible as the wholemolecule. To facilitate the protein-RNA docking, a benchmark dataset has been developed. Theautomated calculations of the structural and physicochemical parameters of protein-RNA interfacescan be performed using the webserver ‘PRince’, which has been developed here.

Dr Ankita SoniImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CHRI, Gwalior

(MP)Designation : PhD

Ovarian cancer has progressively become leading cause of death from gynecological malignancyworldwide and has emerged as second most common gynecological malignancy in India. OC is also thirdleading cause of death affecting Indian women after cervical and breast cancer. The present studyevaluates socio-demographical, clinical and histopathological detail of OC patients so as to examinethe role of effective clinical and non-clinical factors in the diagnosis of ovarian cancer and toincrease awareness of gynecological malignancy among central region of India. This study wasperformed in Cancer Hospital and Research Institute, located in Gwalior Madhya Pradesh. We recordedthe data of 56 clinically proven ovarian cancer patients during period of August 2013 to August 2014and analyzed different variables including age of patients at diagnosis, parity of patients,clinical profile includes levels of CA125, histological types and socio-demographic data. Thepresent study found 87.5% of the cases with malignant ovarian cancer while only 12.5 % of the caseshad benign tumor. In this study, abdominal distension was found as the most common symptom ofcomplaints (28.5%) following abdominal pain (25%) and lower abdominal lump (23.2%). In the presentstudy, multiparty was found to be associated with the malignant ovarian cancer in 76.7% patients. Ithas been observed that epithelial ovarian cancer was the most common malignant type and both serouscyst adenocarcinoma (23.21%) and mucinous (19.64%) was the common variant of malignant ovariancarcinoma in our study. Thus we could conclude that the changes in socio-demographic, menstrual andreproductive factors, life-style related factors may also contribute to changes in the incidence offuture ovarian cancer in India.

Ms DEVIKA SOROKHAIBAMImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : MANIPUR

UNIVERSITYDesignation : Ph.D Research

scholar

Nutritional studies of wild edible aquatic plants of Manipur

Devika Sorokhaibam and G.A. Shantibala Devi* Department of Life Sciences Manipur University, Canchipur-795003 *E-mail: [email protected]

Abstract: In the present context of ever increasing food crisis it is important to understand the nutritional significance of various unexplored wild edible aquatic plants. Manipur being located within a biodiversity hotspot region of the world is endowed with various species of wild flora and fauna. There is a need to tap the hidden potential resources for proper utilization. Out of the 51 wild edible plant species reported so far, only 21 species have been studied for their nutrition content. Some of the important findings from these studies include high protein, fat, carbohydrates, nitrogen, copper and zinc content in Lemanea australis, high potassium content in Zizania latifolia, high sodium and phosphorus in Fagopyrum esculentum, and high lignin content in Hedyotis auricularia. The presence of anticancer activity was recorded in N.peltata, presence of antioxidant in N.hydrophylla and N.indica and other important secondary metabolites such as alkaloids, flavonoids, phenols, tannins, steroids and glycosides in N.hydrophylla, N.indica and N.macrospermum respectively. With the ever increasing demand for food to meet the global population growth, it is important to understand the nutritional contents of the unexplored wild edible plants of Manipur which have received very little attention, so as to encourage them for mass cultivation for food security and as a valuable source of balanced diet during conflicts or famines, and also to conserve them for future use in genetic transformation and breeding programme.

Keywords: Manipur, unexplored, wild edible aquatic, nutrition.

References: 1. Khan, ZR.; Chowdhury, NS.; Shamin, S.; Sohrab, MH. Asian. Pac. J. Trop. Biomed. 2018, 8(2), 113-119. 2. Jain ,A.; Sundriyal, M.; Roshibala, S.; Kotoky, R.; Kanjilal, PB.; Singh, HB.; Sundriyal, RC. J. Ethnobio. Ethnomed. 2011, 7(29), 1-17. 3. Dogan. Austin Food Sc. 2018, 1(2),1006

Mr ALOK KUMAR SONIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DRDE-DRDO

GWALIORDesignation : SENIOR RESEARCH FELLOW

Leishmaniasis is not single entity but comprise a variety of syndromes that caused by the parasiteinfection of genus Leishmania. Approximately 12 million people affected worldwide while 350 millionpeople are at risk every year. On the basis of symptoms and causative organism cutaneous andvisceral Leishmaniasis (VL, fatal) is most common clinical form. The available drugs are limited innumber and major problem associated with increasing resistance. Our hypothesis is to standardize thecolorimetric method for ketose determination. This can eventually use in determination of substratespecificity of LdRpiB among aldoses and ketoses and to find out another more good candidate as forLdRpiB other than ribose 5-phosphate. Since the RpiB is the only Rpi present in the parasite, andhas no homologue in higher animals, opens up the possibility of considering it as a new potentialtarget for the chemotherapy of Leishmaniasis. Firstly, LdRpiB was expressed and purified frompET30a-LdRpiB construct transformed into BL21 (DE3) strain of E. coli. The purified samples wereloaded on to 12.5% SDS-PAGE to check integrity of the purified protein. In second step westandardized and validate the method for estimation of ketoses. Standardization of ketoses wasoptimized with two method i.e. PAR method and Cysteine Carbazole method. Due to more sensitivity andless time consumable, Cysteine Carbazole method was used for the estimation of ketoses. In presentstudy we have demonstrated the substrate specificity of the LdRpiB by specific activity for variousaldose substrates. The enzyme activity was determined for aldose sugar and sugar phosphate such asribose 5-phosphate, ribose, arabinose, allose and talose. The LdRpiB showed activity againstribose-5-phosphate, along with arabinose and ribose than the talose and allose. Results show thatrLdRpiB had varied activity with the different substrates. LdRpiB shows substrate specificity towardaldose sugar. Apart from the natural substrate R5P, it was observed that D-arabinose and D-ribosehad come out as another substrate candidate for LdRpiB. These results further can be explained fordesigning the inhibitors for LdRpiB which will further help in understanding the enzyme.

Ms AMREEN SHAMSADImage Delegate ID Theme Details


Research


OF LUCKNOWDesignation : Ph.D

SCHOLAR

Abstract

Gestational diabetes mellitus (GDM) is a complication of glucose intolerance recognized first time in pregnancy during 24-28 weeks of gestation. This chronic hyperglycemic condition occurs due to pancreatic ?-cell dysfunction leading to decreased insulin sensitivity with advancement of pregnancy. Previous studies suggest that women with GDM might develop type 2 diabetes later. Many risk factors are associated with GDM which include advanced maternal age, family history of GDM or T2DM and obesity. GDM is a condition which affects both mother and child. It causes several maternal and fetal complications such as preeclampsia in mothers and neonatal hypoglycemia, macrosomia, hypocalcaemia, still birth and congenital malformations in infants. Prevalence of GDM is increasing at an alarming rate. GDM affects approximately 16.5% pregnancies worldwide. The exact molecular mechanism of its development is not known, but new diagnostic and treatment strategies are required to be developed. Physiological similarities between T2DM and GDM suggest that they could share a common genetic background. Thus the genes found to be associated with T2DM genes may also play some role in GDM risk. Several studies reported that alteration in gene expression causes ?-cell dysfunction which serves as a hallmark for GDM. Recent studies have shown that microRNAs (miRNAs) are either upregulated or downregulated in GDM. The miRNAs play an important role in gene expression. Altered expression of specific miRNAs has been reported to be associated with several diseases. Some miRNAs like miR-181, miR29a, miR-222 are associated with GDM. Further investigations are needed to confirm whether these miRNAs can serve as potential biomarkers for GDM.

Keywords: Gestational diabetes mellitus, Pregnancy, T2DM, miRNA, Biomarkers

Mr Mayur Kumar SonagaraImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Anand Agricultural University

Designation : Ph.D. (Scholar) (Genetics and Plant Breeding)

Today, we are facing a major problem of exponentially increasing human population, which isprojected to reach 9 billion by 2050. The greatest challenge for breeders is producing a multifoldyield of crops, which can take up to 12-15 years to release any new variety that could actually makea difference. As an answer to this alarming situation, came genome editing with CRISPR (ClusteredRegularly Interspaced Short Palindromic Repeats), which is a unique technology for genome editing inthe world of science. It is faster, cheaper, and more accurate than previous techniques of editingDNA and has wide range of application over the GMO’s (Genetically Modified Organism). Whereas, theCRISPR/Cas (CRISPR associated protein system), is a prokaryotic immune system that confersresistance to foreign genetic elements such as those present within plasmids and phages thatprovides a form of acquired immunity. Among its potential applications, one of the most important isthat direct delivery of CRISPR/Cas9 Ribo Nucleo-proteins to the protoplast system enables targetedgene editing and paves the way to the generation of DNA-free genome edited several plants.CRISPR-Cas9 doesn’t require foreign genes, nor does it necessarily need a bacterium to introducethe system into the target cells. It leaves no trace, and the genome that has been modified isalmost identical, biosimilar is to the original. By the integration of CRISPR technology in breedingtechniques, we can be able to overcome the ethical issues associated with GM technology as well asto ensure considerably higher yield of crops by genetic manipulation. The gene editing ability thistechnology in crops has resulted in a boom in the study and production of modified foods. CRISPRwill help in increasing the shelf life and nutrient contents of food items.

Ms Kantisree GoswamiImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Charuchandra

College, KolkataDesignation : Assistant

Professor in Zoology

ESSENTIALITY OF NANOTOXICOLOGY IN SAFEGUARDING THE HUMAN HEALTH: AN OVERVIEW Kantisree Goswami Assistant Professor in Zoology Charuchandra College 22 lake Road, Kolkata-29 Email id: [email protected]

In recent years, nanoparticle based technologies are benefitting us in several ways. Nanoparticles are being used for developing different delivery systems of several biocompatible materials within the human body, such as chemotherapeutic and other drugs, vaccines, genes, food supplements etc. It is well known that nanoscale particles possess many novel properties such as self-assembly, size effects, large surface area, ultrahigh reactivity and quantum effects because of their very small size and unique structures. But as we know that any new development must have its own pros and cons, the rapid development of nanotechnology is likely to become new sources of human or environmental hazards through inhalation, ingestion, skin uptake, or injection of engineered nanomaterials in different consumer products. So far, research results suggest that nanoparticles may cause adverse effects on human health at their portal of entry, which show difference from the bulk materials of the same chemical composition. These nanoparticles easily enter the environment via various routes, and ultimately enter human body through direct routes such as dermal and oral exposures, nanodrugs, or through indirect routes such as the food chain, etc. Human skin, intestinal tract and respiratory tract are always in direct contact with the environmental nanoparticles. For instance, skin, as a structural barrier between the environment and the body, plays an important role to protect against break-in of exogenous particles. Respiratory tract, generally divided into three segments, upper respiratory tract, respiratory airways and lung, most of which exists merely as a piping system for air to travel in the lungs. Gastrointestinal tract, also known as the digestive tract, can uptake, transport, digest and adsorb various substances such as nutrients, water and vitamins from food. In addition, other physiological systems such as cardiovascular system and central nervous system may have chances to interact with exogenous nanoparticles circulated or transported from the above exposure routes. Nanotoxicology is the study of the nature and mechanism of toxic effects of nanoscale particles on living organisms and other biological systems. This particular branch of toxicology must be developed further, for providing us standard assay and evaluation methods for nanomedical/nanobiological applications, so that we can get an ultimate safeguard and assurance while consuming something with nanoproducts. Key words: Nanoparticles, Novel properties, Delivery systems, Human health hazards, Nanotoxicology

Mr Gourav ChoudhirImage Delegate ID Theme Details


Research


institute of Technology DelhiDesignation : Research

Scholar

Evaluation of plant secondary metabolites for acetylcholinesterase inhibition as a candidate drug to manage Alzheimers disease Gourav Choudhir*, Satyawati Sharma, and Dr. Hariprasad P. Center for Rural Development and Technology Indian Institute of Technology Delhi, Hauz Khas, IIT Delhi *[email protected]

Abstract: Background of the problem Dementia is a leading cause of death in the world. A large number of people affected by dementia. Alzheimer's is the most common type of dementia leads to a high amount of death. There are several molecules available to target Alzheimer's disease. Still, there is no promising treatment for Alzheimer's. Problem- The pathology of Alzheimer's disease starts at an early stage. There is no biomarker available to detect Alzheimer's disease at an early stage. So we need a natural source which can be taken as food and can reduce the probability of Alzheimer's disease. Method used The extraction of the metabolites was done by the green extraction method into the different solvent by polarity(Nonpolar to polar). The plant extract was kept into the oven at 37? for evaporating off the excess solvent. The dried plant extract used for enzyme inhibition assay. The acetylcholinesterase enzymes inhibition assay performed the Elman method. Result and conclusion This work is a preliminary attempt to the identification of the natural metabolites for the Acetylcholinesterase inhibition for slow of the progression of Alzheimer's disease. The natural metabolites have always been an attraction for drug discovery due to their chemical diversity. The further identification and purification of the molecular may have a property to slow the disease progression. References Ellman, G. L., Courtney, K. D., Andres Jr, V., & Featherstone, R. M. (1961). A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical pharmacology, 7(2), 88-95

Ms solmaz arefImage Delegate ID Theme Details


Research


mysoreDesignation : research

scholar

Study of Insulin receptors and glucose transporters on RBC ghost membrane Solmaz Aref*1 , Dr. Vidya Chandavar1, 1 Department of Molecular Biology, Yuvraja’s College, University of Mysore, Mysore Email: [email protected]; [email protected] Dr. Gopal Marathe K2, Dr K. Kemparaju2 2 Department of Biochemistry, University of Mysore, Manasagangotri, Mysore 570006, India Email: [email protected]; [email protected]

Insulin is a peptide hormone secreted by the ? cells of the pancreatic islets of Langerhans and maintains normal blood glucose levels by facilitating cellular glucose uptake, regulating carbohydrate, lipid and protein metabolism and promoting cell division and growth through its mitogenic effects. Elevated level of glucose in the blood is known to cause membrane damage. By using human erythrocytes the present study has examined the changes that are induced by hyperglycemia in the absence or presence of a different amount of insulin on the activity of RBC membrane. Insulin receptors studied on normal human RBC cells was carried out by isolating RBC ghost membrane. Human erythrocytes were separated by sedimentation at 2500 g and 4oC for 5 min using MSE Mistral 4L. The plasma and buffy coat were removed by aspiration. The erythrocytes were then washed three times by re-suspension and sedimentation in ice-cold NaCl (152 mM). Finally, erythrocytes were suspended in Krebs-Ringer bicarbonate at pH7.4, 1:1 (v/v) followed by hemolysis and centrifugation. The supernatant was quantified by Lowry’s method. Erythrocytes incubated with different concentrations of glucose, insulin and glucose+insulin along with control were incubated at 37oC for 3 hours, later it was estimated with ELISA glucose estimation kit. We achieved a result with a differentiation in graph showed that RBC has receptors for insulin and it can absorb glucose as well. The consequent elevation of glucose in the blood plasma affects primarily the tissues with insulin-independent uptake of glucose like lens fiber cells, the vascular endothelial cells and red blood cells.

References: 1. Gisela Wilcox. Clin Biochem Rev. 2014, 19, 26. 2. Charles Wilson and ScotWt . Peterson. 1986. 261, 2123-2128. 3. Omar S. Hajjawi American J of Biomedical and Life Sciences. 2013, 1, 44-52. 4. Mihaela Stanescu, Gabriela Zamfirescu, Dana Iordachescu. Rom. J. Biophys. 2002, 12, 117-128.

Ms PRIYA DIXITImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Era’s

Lucknow Medical College & Hospital/ERA University,

Lucknow-03Designation : Research

Scholar

Association of Vitamin D Receptor (FokI, BsmI, TaqI and ApaI) Gene Polymorphism with Bone Mineral Density and their effect on 25-Hydroxyvitamin D Level in North Indian Postmenopausal Women with Osteoporosis Priya Dixit*, Tabrez jafar** Department of Personalized Molecular Medicine, Era University, Lucknow-226003 *Email: [email protected], **Email: [email protected] *Presenting Author **Corresponding Author

Abstract: Osteoporosis is characterized by low bone mass and defect in micro-architecture of bone and increased risk of fractures. It has been considered as a multigenetic disorder which is mediated by the action of many genes and environmental factors that adversely. Currently, it has been estimated that more than 200 million people are suffering from osteoporosis. It is more common in females as compared to males with ratio 2:1 and particularly in postmenopausal women. Vitamin D, through its principal bioactive form 1,25-dihydroxyvitamin D3(1,25-(OH)2D3) plays a pivotal role in bone metabolism. So this study will improve our knowledge of the development and progression of osteoporosis in post menopausal women. It may identify new targets for drug development and, therefore, novel interventions to prevent osteoporosis . Objective: To investigate the association of VDR gene Bsm I,Taq1, FokI and Apa I polymorphism with BMD in North Indian postmenopausal women with and without osteoporosis. Material & Method: 254 postmenopausal osteoporotic women (WHO criteria) and 254 postmenopausal non osteoporotic women were included in this study. BMD (g/cm2) was measured by dual energy X-ray absorptiometry (Lunar Prodigy, Madison, WI, USA) at lumbar spine L1-l4, femoral neck, hip, forearm left skeletal site. 5ml of blood was collected through venupuncture.VDR (Bsm I,Taq1, FokI and Apa I) gene polymorphism were assessed by the PCR- RFLP method .The PCR amplicon were Analyzed by ELISA. Result: Our results demonstrated an association between the VDR gene TaqI polymorphism and lower BMD at the L1-L4 lumbar spine, forearm and hip in postmenopausal osteoporotic women.The bb genotype of BsmI polymorphism and ff genotype of FokI polymorphism is also associated with the lower BMD in the L1–L4 lumbar spine and hip.We did not found any significant results in case of ApaI. Conclusion: VDR gene TaqI , BsmI and FokI polymorphism modulates differences in BMD in postmenopausal women with osteoporosis and can be used as diagnostic marker for BMD. Reference: 1. Zmuda, J.M., Cauley, J.A., & Ferrell, R.E. Molecular epidemiology of vitamin D receptor gene variants. Endocrinology Reviews, 2000; 22, 203 – 21.

Ms NEELAM MAHALAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : BITS-PILANI


New global cancer data (2018) suggests that the global cancer burden has risen to 18.1 million cases and 9.6 million cancer deaths. Most common cancer treatment modalities are a suitable combination of surgery, chemotherapy, radiotherapy, and hyperthermia. The side effect caused by the treatment often limit patient compliance and make treatment a very difficult task. The major drawbacks are the side effects caused by various forms of anticancer drug therapy. The most important problem in cancer therapeutics is the lack of availability of anticancer drugs devoid of side effects. Milk proteins are a major source of bioactive molecules. Numerous milk proteins and/or their derivatives such as HAMLET, lactoferrin, CLA, etc. are known to possess anticancer properties. Camel milk has been traditionally used for cancer prophylaxis and treatment in middle eastern countries. The anticancer property of camel milk remains largely unexplored. Camel milk has earlier been used for the treatment of various diseases like diabetes, diarrhea, food allergies, and liver diseases, besides being a very upcoming nutraceutical Camel milk proteins are highly thermostable besides being resistant to acid hydrolysis. The present study explores the anticancer property of camel milk and its protein components. For this, camel milk was collected from an authorized camel milk distribution center. From this, the two major milk components namely, casein and whey were separated by acid precipitation. The anti-cancer property of the camel milk, its whey and casein fractions was estimated by the MTT assay against a cell line of cervical cancer origin, namely, Hela. The anticancer property was found to be associated with the whey and not the casein fraction. The ability of whey to induced nuclear fragmentation was also studied by DAPI staining using fluorescence microscopy. Furthermore, its ability to activate caspase 3, the vital enzyme involved in programmed cell death was also investigated. In order to understand the mechanism involved, the ability of whey to down-regulate cancer-promoting genes like CYP1A1 was studied by real time PCR. The whey fraction was subsequently investigated for its wound healing ability by cell migration assay. Further purification of whey was done by Gel filtration chromatography. Results from the above experiment indicate an anticancer potential of camel milk. Future work will focus on molecular mechanisms associated with the anticancer property mediated by camel milk.

Mr Dhruv MishraImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : GOVIND

BALLABH PANT UNIVERSITYDesignation : Student

Bacterial pathogens are slowly developing resistance against the commonly used chemical controlmeasures. Hence, devising alternative strategies viz., developing novel drug molecules and efficientdrug delivery systems are very much required for e?ective treatment of diseases. Greater surfacearea available for ligand binding and higher catalytic activity of nanoparticles has popularized theuse of nanoparticles in the drug industry. In the present study, zinc oxide nanoparticles (ZnO NPs)were synthesized by green route (leaf extract of Catharanthus roseus) followed by characterizationusing Fourier Transform Infrared spectroscopy (FTIR), UV-Visible spectrophotometry and ScanningElectron Microscopy (SEM). For determination of element ratio Energy-Dispersive X-ray spectroscopy(EDX) was performed and Dynamic Light Scattering (DLS) was used to determine the particle size. FTIRspectra analysis suggested that phenolic compounds played a crucial role in the biosynthesis of ZnONPs. The synthesized ZnO NPs have shown antibacterial efficacy against both Gram-positive andGram-negative pathogens as indicated by the zone of inhibition. Overall, the results elucidated arapid, cost-effective, environment-friendly and convenient method for ZnO NPs synthesis, which couldbe used as a potential antimicrobial agent against drug-resistant microbes.

Mr SARBASHRI BANKImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Vidyasagar

UniversityDesignation : DST INSPIRE

SRF

Impairment of Insulin/GLUT4 signaling by dermcidin through the inhibition of cGMP/NO regulation Sarbashri Bank1*, Smarajit Maiti1, Subrata De2, Suman Bhattacharya1, Andreas Koschinski3, Manuela Zaccolo3, Santanu Guha4, Asru K Sinha5 1Dept. of Biochemistry, Vidyasagar University, Midnapur 2Dept. of Zoology, Vidyasagar University, Midnapur 3Dept. of Physiology, Anatomy and Genetics, Oxford University, UK 4Dept. of Cardiology, Calcutta Medical College and Hospital, Kolkata 5Sinha Institute of Medical Science and Technology, Kolkata *[email protected]

Development of hyperglycemia is highly prevalent in hypoxia-experiencing persons, tobacco-consuming individuals and post-menopausal women. The mechanism behind diabetes-associated vascular-disorders remains speculative. Dermcidin, an 11 kDa-protein plays a crucial role in acute myocardial infarction through the inhibition of nitric-oxide. So, dermcidin has been tested in the genesis of diabetes in human and rodent-models under different physiological conditions. In mice, injection of dermcidin augmented the blood sugar level with a concomitant reduction of nitric-oxide levels. Dermcidin triggers the release of glucose from liver/muscle/kidney; and antagonizes the effects of insulin even more effectively than glucagon. Immunohistochemical studies showed that dermcidin inhibits GLUT-4 translocation and impairs nitric-oxide production. Here, we show that tobacco consumption or hypoxia might provoke hyperglycemia induced by dermcidin by concomitant down regulation of NO-signaling, GLUT4-function and insulin-sensitivity. Neutrophils showed significantly increased glucose mediated insulin, GLUT-4 and GANOS expression which were missing in postmenopausal women due to the dermcidin. Bioinformatics study like STRING analysis suggests the role of DCD on soluble guanylate-cylase activity in higher primate. Our FRET-imaging studies demonstrate that DCD-induced NO deregulation impairs cGMP mediated cellular signaling. Molecular docking experiments (AUTODOC/PATCHDOC) decisively show high affinity binding of DCN to GLUT-4, insulin and its receptor. Synergism of these effects resulted in breakdown of glucose homeostasis machinery in individuals under wide variety of stressors.

Acknowledgement: Sarbashri Bank would like to thanks Dept. of Sc. & Tech. Govt. of India for providing DST/INSPIRE fellowship/2014/308. Sarbashri Bank is grateful to Newton-Bhabha PhD Programme for providing short-term PhD programm (DST/INSPIRE Fellowship/NBHF/2017/9) at Oxford University.

Mr Rajesh Kumar MallaImage Delegate ID Theme Details


Research



Scholar

Larvicidal activity of seed extracts of purple cleome, Cleome rutidosperma DC. against the mosquito vectors Culex quinquefasciatus and Aedes albopictus Rajesh Kumar Malla1 and Goutam Chandra1* 1Mosquito, Microbiology and Nanotechnology Research Units, Parasitology Laboratory, Department of Zoology, The University of Burdwan, Burdwan-713104, West Bengal, India *E-mail: [email protected] In order to develop eco-friendly alternative to the chemical larvicides searching of new mosquito larvicide of botanical origin with better larvicidal potentiality is the prime objective of our present experiment. Cleome rutidosperma seed extracts were selected for evaluation of larvicidal efficacy against the third instar larvae of Culex quinquefasciatus and Aedes albopictus. At first air dried seeds were extracted in water for 72 hrs in soxhlet apparatus and excess water was subjected to lyophilisation to get a water free extract. Then this water free extract was subjected to liquid–liquid extraction with petroleum ether, ethyl acetate and methanol to obtain their respective fractions. Larvicidal bioassay was performed with these fractions following the standard protocol of World Health Organization. The non-target mosquito predators, Toxorhynchites sp. (mosquito predator), Gambusia affinis (predatory fish) and Diplonychus sp. inhabiting with mosquito larvae were also observed for mortality and other abnormalities with each fractions for three days. Predator safety factor (PSF) or suitability index was calculated for each species of predator. Qualitative phytochemical screening tests and functional group identification by FT-IR analysis in most effective fraction were also performed. Larvicidal activities of the fractions were dose dependent. Among the fractions, the maximum larvicidal activity was shown by the methanol fraction against the third instar larvae of both extracts with LC50 (50% lethal concentration) values of 0.16 mg/l and 0.12 mg/l after 24 hrs of exposure. Predator Safety Factors of different mosquito predators with respect to third instar larvae of vector mosquitoes exposed to each of fractions indicated that test extracts have little to negligible effects on natural predators of mosquito larvae with lowest suitability index of 42.26 and 36.56 for the methanol fraction against Diplonychus sp. with respect to Cx. quinquefasciatus and Ae. albopictus after 24 hrs exposure. Qualitative phytochemical screening revealed moderate presence of flavonoids, terpenoids, alkaloids and trace amounts of tannins and saponins. Functional groups in FT-IR spectrum obtained were alcohol, amide, imine, amine, aldehyde, azo groups and hydrazines. The present investigation suggests the possible use of this botanical source as an ideal eco-friendly larvicide against both the Cx. quinquefasciatus and Ae. albopictus larvae.

Mr PRIYANK JAISWALImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : School of Tropical Medicine, KolkataDesignation : PhD scholar

Post Kala Azar Dermal Leishmaniasis (PKDL), is mostly observed as dermal manifestation among patients with previous history of Visceral Leishmaniasis, affecting individuals worldwide [1-2]. Recent reports from our lab has indicated the importance of glycated Circulating immune complexes (CICs) as an efficient diagnostic tool for both early detection as well as progression of Macular (MAC) PKDL cases [3]. With such huge implication of CICs in PKDL diagnosis, this study is designed to understand the biological significance of CICs in PKDL disease progression. Previous reports have indicated huge infiltration of CD8+ T cells with enhanced granzyme production during dermal manifestations of PKDL which in turn assist in disease progression [4-6]. Further studies have indicated the strategy of leishmania parasites of utilizing apoptotic cells as vectors to escape host protective inflammatory immune response. Apoptotic promastigotes facilitates infection and prevent neutrophils activation. Viable amastigotes expose PS and mimic apoptotic cells [7, 8]. This study targets to understand whether CICs of PKDL patients could induce similar response in healthy PBMC when induced in vitro. Healthy PBMC were isolated from 5ml venous with gradient separation using Lymphoprep. Glycated CICs were isolated from PKDL patients’ blood. Healthy PBMC were treated with PKDL patients’ CICs (at physiological concentration) in vitro and were analysed for complement activation, Granzyme production and Apoptosis by FACS. Healthy PBMC when treated with patients CICs indicated increased deposition of C3b on CIC treated PBMC compared to untreated PBMC. CIC treated PBMC further showed increased granzyme b production followed by increased apoptosis rate as compared to untreated PBMC All data were statistically significant (p Our results for the first time indicated that Glycated CICs stands as an important role players for disease progression among PKDL patients. In vitro treatment of healthy PBMC treated with PKDL patients CICs indicated similar immunological consequences as observed among PKDL patients. Thus effective clearance of CICs from the system should led to efficient disease treatment.

Ms Khushboo .Image Delegate ID Theme Details


Research


AllahabadDesignation : Research

Scholar

Abstract Depressive disorders are among the most common psychiatric diseases and are expected to become the second most common form of psychiatric illness by the year 2020. Commonly available chemical drugs used for nervous system disorders have various unfavorable side effects, due to this, the public is attracting to herbal medicines. In the present study, we have investigated the antidepressant and neuroprotective effect of garlic extract against Reserpine induced depression in the rat model. Rats were divided into four groups which are, 1) control, 2) Reserpine, 3), reserpine with garlic extract and 4) reserpine with fluoxetine. The forced swimming test was used to evaluate the antidepressant activity of garlic extract. The antioxidant enzyme levels including SOD, GST and CAT, and metabolic enzymes were significantly decreased in the depressed rat brain. The level of serotonin and acetyl-cholinesterase are also altered which suggests the abnormal dopamine cycle in brain. A histological study shows significant malformations in brain parts. Reserpine induced a significant increase in the immobility time of rats in the forced swimming test and treatment with garlic extract ameliorated the reserpine induced changes. Reserpine-induced reduction in brain marker enzymes was improved using garlic extract. Also, it reduces the MDA level in Brain. The study shows the significant neuroprotective and antidepressant activity of garlic extract against the reserpine induced depression.

Keywords: Neuroprotective, Antidepressant, Phytomedicine, Oxidative stress, and Serotonin

Ms Pratibha SharmaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Panjab


Research Fellow

Background: Peptides have started establishing their therapeutic niche with their attractive pharmacological profile and intrinsic properties. They represent an excellent starting point for the design of novel therapeutics and their specificity has been seen to translate into excellent safety, tolerability, and efficacy profiles in humans differentiating them from traditional small molecules. In the present clinical settings, when conventional antibiotics are fast becoming ineffective against many microbes, host defence peptides (HDPs) can combat resistance, emerging out loud as novel antimicrobials. Problem: The key obstacles for their clinical application are toxicity against eukaryotic cells, poor efficiency and lack of knowledge about the mechanisms of action. Various structure activity relationship studies have revealed that the effectiveness of short alpha-helical HDPs depends on mixture of cationic and hydrophobic aminoacids, arranged to form an amphipathic peptide (Sang et al.,2017). One of the classes of HDPs called as cathelicidins, particularly the N-terminal fragment of chicken cathelicidin-2 (N-15 CATH-2), have shown potent broad spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, but with a noticeable toxicity to mammalian cells (Van Dijk et al., 2009). Methods: Responding to this need, this study focuses on in-silico designing of peptide analogs with enhanced antimicrobial activity and low cytotoxicity using the N-15 CATH-2 sequence as template based on the physiochemical parameters like hydrophobicity, cationicity and amphipathicity. A thorough physiochemical analysis of the designed peptide analogs and further their secondary structure validation through Molecular Dynamics (MD) studies and Circular Dichroism. The antimicrobial activity of the peptide analogs was evaluated by determining the MIC against Gram-positive Staphylococcus aureus and Gram negative Escherchia coli and Salmonella enteric serovar Typhimurium. The hemolytic activity, cytotoxicity and serum stability of the peptide analogs were also measured. Results and Conclusion: Based on these studies, we were able to put forward new and novel analog of N-terminal fragment of chicken cathelicidin-2 which is more potent in terms of displaying improved antimicrobial activity against both Gram-positive and Gram-negative bacteria and decreased hemolytic activity. The results helped us to explore the role of amphipathic character in structure and activity of the peptide analogs. References: • Sang, P.; Shi, Y.; Teng, P.; Cao, A.; Xu, H.; Li, Q.; Cai, J. Curr .Top. Med. Chem.2017,17(11), 1266–1279. • Van Dijk, A.; Molhoek, E.M.; Veldhuizen, E.J.; van Bokhoven, J.L.; Wagendorp, E.; Bikker, F.J. et al. MolImmunol.2009 ,46(13),2465–73.

Ms Mrinal GuptaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : King George

medical universityDesignation : PhD Scholar

Dexamethasone, a glucocorticoid used as an anti-inflammatory agent for the treatment of several disorders including allergy and auto-immune diseases. However, its clinical applications are restricted due to several metabolic side effects including insulin resistance, diabetes, obesity, etc. Recently, phytopharmaceuticals have gained importance as therapeutic drugs for the treatment of various diseases. Berberine, a bioactive compound isolated from Coptidis Rhizoma, possesses anti-diabetic activity, which was confirmed in the animal models of type 1 diabetes (STZ-induced). However, its therapeutic effect is not studied yet in the animal models of dexamethasone-induced type 2 diabetes. Therefore, in the present study, we investigated the effect of berberine on dexamethasone-induced glucose intolerance and insulin resistance. Swiss albino mice were randomly divided into the following groups: control group (saline-treated), dexamethasone group (1mg/kg body weight DEXA, i.m.), dexamethasone + metformin group (250 mg/kg body weight, oral), dexamethasone + berberine groups (100 and 200 mg/kg body weight, oral). Blood sugar and body weight were evaluated on the 14th day. Glucose tolerance, insulin tolerance, pyruvate tolerance, and body fat mass were evaluated at the end of the experiment. Drug treatment was started according to the above mentioned scheme from 15th day of dexamethasone treatment and continued upto 30th day. Our results showed that berberine suppresses the hepatic glucose release and improves glucose tolerance in the dexamethasone-treated animals; however berberine does not have any effect on the fasting blood glucose. Further, dexamethasone treatment increased the total fat mass in mice as assessed through echo-MRI, which was ameliorated by berberine. Overall, our results suggest that berberine improves glucose tolerance by increasing glucose clearance and inhibiting hepatic glucose release and decreases obesity by suppressing fat mass gain. Therefore, berberine may be potential therapeutic agent to treat glucocorticoid-induced glucose intolerance and obesity.

Dr SOMNATH MAZUMDERImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NATIONAL

INSTITUTE OF BIOMEDICAL GENOMICS

Designation : PROJECT COORDINATOR

Non-steroidal anti-inflammatory drug, Indomethacin, impairs mitochondrial dynamics and cellular respiration to induce death in gastric cancer cells: the central effect targeting cellular metabolic hub

Somnath Mazumder1,2, Rudranil De2, Subhashis Debsharma2, Samik Bindu3 and Uday Bandyopadhyay2*

1National Institute of Biomedical Genomics P.O.: N.S.S., Kalyani 741251, 2Division of Infectious Diseases and Immunology, CSIR-Indian Institute of Chemical Biology, Kolkata- 700032; 3Department of Zoology, Cooch Behar Panchanan Barma University, West Bengal 736101

*Contact Author Email: [email protected]

Gastric cancer is the 5th most common cancer in men while 6th most common cancer in women and also the 2nd most common cause for cancer-related deaths in Indians. Treatment against cancer is severely challenged by toxic side effects of the canonical chemotherapeutic drugs. Interestingly, “drug repurposing” of FDA-approved painkillers including aspirin, diclofenac, celecoxib and indomethacin as cancer-fighters have yielded fruitful anti-neoplastic results against prostate, breast, ovarian and colorectal carcinomas. However, scanty reports exist on the probable anti-cancer effects of non steroidal anti-inflammatory drugs, especially indomethacin, against gastric cancer. Owing to its COX-2/PGE2-dependent and -independent dual mode of cytotoxic actions, Indomethacin demands special attention as a promising candidate worth of “drug-repurposing” for gastric cancer chemotherapy. In the present study, the aggressive-phenotype human gastric adenocarcinoma (AGS) cells were used to put forward a hither to unknown effect of indomethacin, crucial for inducing anti-cancer effect by hitting at the base of cellular metabolism. By high resolution live-cell confocal imaging, super resolution-based immunocytochemistry and immunoblot analyses it was found that indomethacin severely disrupted mitochondrial structural dynamic homeostasis by triggering hyperfission for inducing cell death. Indomethacin activated the protein kinase C?-p38 MAPK-dynamin-related protein 1 (DRP1) signaling axis, to trigger oxidative stress, fissogenic serine-616 phosphorylation-dependent mitochondrial recruitment of DRP1 and consequent bio-energetic havoc for inducing apoptosis. These effects were concurrent with mitochondrial depolarization and respiratory failure as evident from FACS and real time respirometric studies respectively. The findings were further validated by hierarchical genetic and pharmacological pathway-blockers including PKC? inhibition, p38 inhibition and DRP1 knockdown, all of which effectively reduced indomethacin-induced cellular damage. Together, the study for the first time identified the effect of indomethacin on gastric cancer cell mitochondrial metabolism that can be rationally exploited in targeted anti-cancer therapy and drug repurposing.

References: 1. Mazumder, S.; De, R.; Debsharma, S.; Bindu, S.; Maity, P.; Sarkar, S.; Saha, S. J.; Siddiqui, A. A.; Banerjee, C.; Nag, S.; Saha, D.; Pramanik, S.; Mitra, K.; Bandyopadhyay, U. J. Biol. Chem. 2019, 294, 8238-8258

Ms Sonali KadamImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Foldscope

Instruments Inc.Designation : Foldscope

Fellow

Science is deprived of the vast intellect of masses due to the non-inclusive and inaccessible nature of the current system. However, citizen science projects are disrupting the system and proving to be highly inclusive in terms of diversity in indigenous knowledge and culture, ecosystems across all geographical terrains and human civilization influenced biome. Science is benefiting from such citizen science projects. The topics studied in these projects vary from phenology studies (Kostadinova, 2011) to the synthesis of novel proteins (Kleffner et al., 2017). Citizen science projects find challenging to study topics that require sophisticated tools such as microscopes. Frugal innovations are not just opening up the possibilities of taking science truly to the masses but also addressing the existing challenges in citizen science projects, like errors due to biases (Conrad & Hilchey, 2011). The paper describes one such invention, Foldscope (Ultra-affordable field microscope, designed to bring hands-on microscopy anywhere) and the ways in which it is contributing to science specifically to biology. Foldscope users around the world, urban and rural, share their observations, ideas, and problems in an online community space (microcosmos.foldscope.com). Data presented in the paper are personal interviews of the Foldscope community members, field observations during bio-walks, and posts on the community website. With work in progress, it is inferred so far, that the community is contributing to the existing knowledge of biology in four ways- a) creating a data set of large numbers of observation (example- pollen database), b) bringing out the gaps in the existing knowledge (example- Couroupita guianensis’s flower structure) and c) open-ended exploration leading to discovery (example- collective intercellular communication in Spirostomum ambiguum) (Mathijssen et al., 2018), d) addressing sustainable development challenges making it multidisciplinary and extending the boundaries of applied biology. Detailed analysis of multiple cases will be presented.

References: Conrad, C. C., & Hilchey, K. G. (2011). A review of citizen science and community-based environmental monitoring: Issues and opportunities. Environmental Monitoring and Assessment, 176(1–4), 273–291. Kleffner, R., Flatten, J., Leaver-Fay, A., Baker, D., Siegel, J. B., Khatib, F., & Cooper, S. (2017). Foldit Standalone: A video game-derived protein structure manipulation interface using Rosetta. Bioinformatics, 33(17), 2765–2767. Kostadinova, I. (2011). Citizen science–the new helping hand for scientists. Current Science, 100(7), 973–976. Mathijssen, A., Culver, J., Bhamla, M. S., & Prakash, M. (2018). Collective intercellular communication through ultra-fast hydrodynamic trigger waves. BioRxiv, 428573.

Mr Mamunur RashidImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : CSIR-Central

Drug Research InstituteDesignation : Senior

Research fellow

Abstract: Flavonoids are phytochemicals that possess variable phenolic structures and have diverse biochemical as well as pharmacological activities. Cladrin (CD), an isoflavone is a major bioactive constituent found in the stem bark of Butea monosperma with remarkable osteogenic activity. Apart from pharmacodynamics studies, preclinical pharmacokinetics analysis plays an important role in the investigation, identification, and optimization of drug-like properties. In the present study, a sensitive UPLC coupled tandem mass spectrometry (UPLC-MS/MS) method was developed validated and successfully applied for the studies of bioavailability, blood partitioning, plasma protein binding, intravenous and oral pharmacokinetics of cladrin in female rats. The CD and 7- hydroxy isoflavone (IS) was separated using the C18 column (5.0 ?m, 4.6 × 50 mm) at a flow rate of 0.60 mL/min. The UPLC-MS/MS system was operated in isocratic mode and acetonitrile and 0.1 % formic acid was used as a mobile phase in the ratio of 65:35% (v/v). Multiple reaction monitoring (MRM) mode of LC-MS/MS was used to quantitate the transitions of CD m/z 299.30 precursor ion [M+H]+ to the m/z 283.10 and 7- hydroxy isoflavone m/z 239.0 precursor ion [M+H]+ to the m/z 137.0. Analyst software version 1.6 (Applied Biosystems, Sciex Canada) was used for the acquisition and quantification of data. The developed and validated method was highly sensitive and has a short run time of 2.50 min with excellent linearity in the range of 0.20-200 ng/mL (R2 > 0.99). Following i.v. administration, maximum concentration (C0) and overall exposure of CD (AUC0-?) were found to be 1630.00±84.85 ng/mL and 2220.14± 294.30 h*ng/mL, respectively at 5 mg/Kg dose. Absolute bioavailability was found to be 19.04% at an oral dose of 10 mg/Kg. Cladrin was rapidly absorbed (Tmax 3.0 h) with a high apparent volume of distribution (15.03±1.79 L/Kg), clearance (2.27 ±0.30 L/h/Kg) and high plasma protein binding. The maximum attainable plasma concentration (Cmax) and overall exposure of CD from zero time to last time point of analysis (AUC0-t) after oral administration at 10 mg/Kg dose were found to 184.00±21.21 ng/mL and 919.70±6.29 h*ng/L, respectively. Besides, the above finding provided useful information for the further preclinical and clinical reference of CD as a potential candidate drug for the treatment of an osteoporotic disorder.

References:

1. Food and D.Administration, Bioanalytical Method Validation. Guidance for Industry, US Department of Health and Human Services, Rockville, MD, 20013.

2. Rashid et al, J PHARMACEUT BIOMED, 2018,152: 289-297

Ms Prajna YellamelliImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : NIT

PuducherryDesignation : M.Tech

student

Skin cancer is the most common form of health concern in the world where almost 75% of the deaths are due to malignant skin cancer. In order to detect skin cancer, dermatologists often use a dermatoscope to enhance the layers of the skin to improve the accuracy of detection. The recent emergence of deep learning methods for medical image analysis has enabled the development of medical imaging-based diagnosis systems that can assist the human expert in making better decisions about a patient’s health. Generally, the computer-aided skin cancer diagnosis system includes five major steps: a) image acquisition b) pre-processing c) lesion segmentation d) feature extraction and e) classification. Feature extraction is not addressed since it is not related to deep learning techniques. Segmentation is also considered as a pre-processing step before the classification of skin cancer as either benign or malignant.

The proposed segmentation model trains the U-Net, a convolution network for biomedical image segmentation, in order to obtain binary masks that will produce the automatically segmented skin image. And the proposed approach achieves promising results, most notably, a Jaccard value of 91.76%. The automatically segmented images achieved the best results with 89.18% sensitivity and 81.74% accuracy, the perfectly segmented images obtained 86.48% sensitivity and 83.90%, while the accuracy improves to 84.69% and the sensitivity decreases 82.43% when using unsegmented images. The precision is recorded at 96.81% when using automatically segmented images and decreases to 95.23% when using unsegmented images. The comparison of the three approaches concludes that segmentation is needed, but not necessarily perfect.

The ISIC (International Skin Imaging Collaboration) dataset for Skin Lesion Analysis Towards Melanoma Detection was used for this work. The dataset is publicly available and contains 1279 RGB images that are divided into 900 training images and 379 validation images. The original ISIC dataset split into training and validation subsets for segmentation.

Further work is going to be carried on the classification of the skin lesion as benign or malignant and implementation of a user-friendly mobile application in detecting the skin cancer.

Mr ARUN GHUGEImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DIRECTORATE

OF HIGHER EDUCATION, GOVERNMENT OF

MAHARASHTRADesignation : ASSISTANT

PROFESSOR

Abstract: As per NCRB 2015 reports, drowning is second major cause of unnatural deaths in India counting 8.9%. Globally, drowning is the third-leading cause of unintentional injury death. When a body is recovered from water, there is usually a suspicion whether it was a case of ante-mortem or post-mortem drowning. In these medico legal cases, presence of diatoms in the body tissues is useful evidence as diatoms do not occur naturally in the body, once entered do not readily decay thus can be used to detect even in heavily decomposed bodies. Our present study intends to identify predominant diatoms in suicide prone water bodies of Aurangabad region and standardize the isolation methods and prepare a database. Water samples were collected from most suicidal prone water bodies and subsequently treated with the strong acid i.e. nitric acid and sulphuric acid, slides were prepared and microscopic analysis was done to generate species diversity data in it. The generated data will help forensic scientist to locate the site and solve the pre and post mortem drowning cases. Thus in drowning cases, a correlation between the diatoms extracted from bone marrow and drowning medium can be established and be useful in determination of drowning site.

Mr A.Swaroop SanketImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICMR-RMRCDesignation : Ph.D Scholar

Introduction: Antibiotics, once considered to be the magical bullets are losing efficacy due to strategic re-action of microorganisms. Efflux pump being one of the major weapons in bacteria, extrude a wide variety of small-molecules out of the bacterial cell causing antibiotic resistance [1]. AcrAB-TolC, an efflux pump found in E.coli is a tripartite protein system that checkmates to even the last line of antibiotics. To combat the global phenomenon of antibiotic resistance, phytochemicals may become the saviors of mankind [2]. In the present study, we have studied the interaction of essential oil compounds from Zingiber officinale (Ginger) and Curcuma longa (Turmeric) with TolC protein of E.coli using in-silico approaches.

Methodology: Essential oil compounds’ data was downloaded from EssOilDB from rhizome of ginger and turmeric. The common compounds were taken into consideration characterization and docking studies. 3D structure TolC protein was retrieved from PDB (PDB ID: 2VDD) and molecular docking studies were carried out using Vina tool to decipher the interactivity of ligands with target protein. PA?N being a known EPI served as reference point for docking studies.

Results: The density analysis shows distribution Zingiberene and Sesquiphellandrene with high percentages in relation to other compounds (Fig 1 a & b). Figure 1: Kernel density plot of (a) turmeric (b) ginger

Molecular docking analysis of ligands with the target protein TolC shows that Sesquiphellandrene interacts with a maximum energy of -4.6 kcal/mol whereas the known inhibitor PA?N binds with -6.7 kcal/mol of energy (Fig. 2 & 3).

Figure 2: Docking scores of ligands to TolC (A)Cineole (B) Curcumene (C) Zingiberene (D) PA?N (E) Nerolidol (F) Bisabolene (G) Sesquiphellandrene Figure 3: Interaction of TolC with (a) PA?N (b) Sesquiphellandrene

Future directives: In vitro analysis of the ligands with derivatives will be assessed followed by molecular dynamics simulation. This may help in designing and discovering phyto compounds as potential efflux pump inhibitors to combat the global problem of antibiotic resistance.

References: 1. Nolivos S., et al, Science, 2019, 364(6442), 778-782 2. Shriram V., et al., Front. Microbiol., 2018, 10, 2018

Acknowledgement: Authors acknowledge DST Ramanujan Fellowship (SB/S2/RJN-038/2016), DBT Ramalingaswami Fellowship

(D.O.NO.BT/HRD/35/02/2006) and ICMR- RMRC, Bhubaneswar for financial support.

Ms VARSHA SINGHImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Birla Institute

of Technology, MesraDesignation : WOMEN

SCIENTIST

Abstract Background: Sampling and isolation of bacteria are the basis for screening of biosurfactant producing microbes. Aim: In the present study using culture–dependent technique, aerobic, endospore forming, gram positive rod shaped bacterium Bacillus aryabhattai SPS1001, identified by 16S rRNA gene sequence (NCBI GenBank Accession number MK024242) was isolated from crude oil-contaminated soil sample of Haldia Oil Refinery, West Bengal. Screening for the production of biosurfactant by Bacillus aryabhattai SPS1001 using petrol as substrates was investigated both qualitatively (Drop Collapse and Microplate Assay) and quantitatively (Oil Spreading, Emulsification Index EI and Surface Tension) by conventional methods. Method and Results: The oil spreading potential of biosurfactant by Bacillus aryabhattai SPS1001 using petrol as substrates shows oil displacement area of 153.10 cm2 and was comparable to SDS (0.1%). They emulsified hydrocarbons xylene (72%), hexane (78%), toluene (68%) more efficiently as compared to oil such as diesel (58%) and kerosene (62%). It also formed stable emulsions (E1,104=100) with mineral and silicone oils. The Bacillus aryabhattai SPS1001 significantly reduced surface tension of culture supernatant from 68.09 ± 0.09 mN / m to 27.953 ± 0.030 mN / m after 48 h of growth. Conclusions: Therefore, the finding in this study confirms the ability of Bacillus aryabhattai SPS1001 to produce biosurfactant that reduce surface tension thereby leading to increase in solubility and emulsification of hydrocarbons and oil. As the bacterium utilizes oil for the production biosurfactant, hence produced biosurfactant could be used for environmental bioremediation processes such as biodegradation. Keywords: Biosurfactant, Hydrocarbons, Bacillus, Surface tension, Emulsification

Ms RUBY BISWASImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : BOSE

INSTITUTEDesignation : JUNIOR RESEARCH FELLOW

Rice has been studied extensively by molecular genetics and constitutes one of the best characterized crop plants with a fine genetic map (1). The complexity of rice genome increases as we try to elucidate its genome sequence where despite of the presence of large intergenic regions it also contains opposite or anti-sense overlapping genes. Even though the functional significance of these overlapping genes remains unclear, one probable explanation could be the double stranded RNA structures formed from the overlapping transcripts which may be processed into small RNAs could serve as important regulatory molecules. Bioinformatic analysis show that in chromosome 1 of rice (IR64) there is an anti-sense gene overlapping OsDREB2A, an important transcription factor induced in response to osmotic and high temperature stresses. DREB2s (Dehydration Responsive Element Binding protein 2s) play a vital role in plant development and abiotic stress response. It interacts with a cis acting DRE (dehydration responsive element) / CRT (C-repeat) sequence and activate the downstream genes responsible to combat osmotic imbalance and high temperature stresses in Arabidopsis thaliana (2). OsDREB2A an ortholog of DREB2A in rice is and is one of the six DREB2 orthologs in rice (3). Here we report that OsDREB2A has two transcripts with identical coding sequences. The 3'UTR region of OsDREB2A transcript 2 is overlapped by another gene in the anti-sense strand. Based on the hypothesis that this overlapping arrangement of genes might lead to the generation of small double stranded RNAs which, may regulate the expression of OsDREB2A gene at the transcriptional or translational level, the following objectives were investigated and reported: • The list of sRNAs targeting the overlapping locus using in silico study. • The expression analysis has shown that the transcript 2 (Os01t0165000-02) is early salinity stress responsive, whereas transcript 1 (Os01t0165000-01) is late salinity stress responsive. • And validating the role of endogenous siRNA in the post-transcriptional gene silencing (PTGS) of OsDREB2A transcript 2 gene using RLM-5'RACE. Collectively the results indicate that the expression of the two transcripts of OsDREB2A are correlated for proper rescuing of the plant from salt stress and their regulation via siRNA mediated PTGS is not the mechanism but paves way for further validation of a siRNA and its regulation via TGS which, remains unexplored in this work.

Mr ASHWIN UDAYImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Acharya

Narendra Dev College, DUDesignation : Undergraduate

student

Thyroid hormones (T4 – Thyroxine and T3 - Triiodothyronine) are very essential hormones requiredfor the development and maintenance of the body systems. Thyroid related problems –hyperthyroidism and hypothyroidism are common in India, especially. The currently available drugsfor hyperthyroidism though are effective in keeping the hormone levels under control, there is ahigh chance of recurrence of the disease condition which forces the patients to be on long andrepeated courses of the drug. Thyroid hormone synthesis done by an enzyme called – Thyroperoxidase(TPO) is inhibited by the currently available drug Methimazole (MMZ). This project aimed atanalyzing the interaction of the drug MMZ with TPO using computational tools. TPO structure wasmodelled using ‘Swiss Modelling server’ and MMZ structure obtained from DrugBank. The structureswere docked together using ‘Patchdock’ and was observed in ‘PyMol’. The site of drug dockingand the known active site residues were compared. The interaction between drug and enzyme wasstudied using 'PyMol' and 'LigPlot'. The available knowledge and data obtained would be used tocompare with other potential molecules which will be obtained by virtual screening, and thus aid indesigning an anti-thyroid drug which can provide better and faster treatment to hyperthyroidpatients.

Ms Rajashree SahooImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICMR-RMRC


Introduction: The natural biopolymer chitosan (Ch) is a cationic biopolymer, and it has similar chemical structure to glycosaminoglycans (GAGs) and offers versatility for biomedical applications [1]. Grapheneoxide (GO) and Ch exhibit antibacterial activity against wide range of bacteria [2]. In the present study, we have prepared chitosan-GO conjugated scaffolds and evaluated the antibacterial potential of the scaffolds against Staphylococcus aureus (ATCC 25923).Methodology: Ch, Ch with 0.05% GO(Ch+GO1) and Ch with 0.1% GO(Ch+GO2) scaffolds were prepared by Freeze drying method(Fig. 1).Figure 1: Three Different type of scaffoldsAntibacterial activity was studied by supplementing 0.25mm scaffolds in media inoculated with bacteria. Of same dimensions and weight, scaffolds were dipped in 30µl of MilliQ water and the scaffolds were immediately placed onto solid media previously swabbed with bacteria. After 24 hours of incubation, optical density of the liquid media was measured as well as number of viable colonies on plates were counted. Results:Bacteria grown on plates in presence of chitosan and/or with graphene oxide didn’t show zone of inhibition (Fig.2) and may be attributed lesser diffusion of Ch and GO from the scaffolds. The visual growth can be seen in Fig.2.

Figure 2: No zone of inhibition in plate.But a significant reduction in viability was observed in case of liquid medium (Fig.3 & 4) as compared to the control demonstrating antimicrobial effect of the prepared biomaterials. Cell numbers when quantified with by counting CFU (Fig.5) also demonstrates similar phenomenon.

Figure 3: Control (without treatment), treatment with Ch, Ch+GO1 and Ch+GO2.

Figure 4: Optical density of Ch, Ch+GO1 and Ch+GO2 scaffold treated samples. Figure 5: Quantification of cell number by cfu count.Future prospective: In-vitro and in-vivo studies will be carried out for the delivery of antibiotics conjugated with Scaffolds. Reference:[1] Samal, S.K., etal., Chemical Society Reviews, 2012, 41, 7147-7194. [2] Giulio Di, M., et al., Antimicrob. Agents Chemother, 2018, 62,7.Acknowledgement: Authors acknowledge DST Ramanujan Fellowship (SB/S2/RJN-038/2016), DBT Ramalingaswami Fellowship (D.O.NO.BT/HRD/35/02/2006) and ICMR- RMRC, Bhubaneswar for financial support.

Mr SANDEEP SANGLEImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : DIRECTORATE

OF HIGHER EDUCATION, GOVERNMENT OF

MAHARASHTRADesignation : ASSISTANT

PROFESSOR

Abstract:

Forensic entomology is the study of insects, in which entomological evidences plays a vital role in estimating the time since death and identification of the deceased. In most of the country’s common method for committing suicide is poisoning, especially in rural areas where the availability of poisons is quite easy in the form of pesticides or insecticides. Each fly shows characteristic time bound development stages, from eggs to adult fly. Geological conditions alter the developmental phases. The present study focus on identification of local fauna, effect of environmental /seasonal changes on the growth and development of insects. The study also considered the effect of insecticide/poisons on insect development. The flesh sample (goat) was collected from slaughter house Cantonment area and studied in the campus of Government Institute of Forensic Science, Aurangabad. Effect of pesticide and different season on the growth, size, number and life cycle of blow flies was studied and the results were recorded. Our future plan is to identify the different toxins from entomological evidences by TLC and advanced instrumentation which will help to determine PMI of poisoned human cadaver.

Ms PRIYANKA HUIDROMImage Delegate ID Theme Details


Research


UniversityDesignation : PhD.Scholar

In the present context of rapid increasing population ,food security has become one of theimportant key issues for the well being of human .The starchy root and tuberous crops play animportant role in food security as it has high carbohydrate content and calorific value .Thetuberous crops can supplement the staple cereals crops like rice, wheat ,maize ,millets ,barley etcat the time of food famine .Various studies have reported that the tuberous crops are a good sourceof carbohydrate, protein and starch .The phytochemical analysis of dry tuber of Colocasia esculentareveals the presence of alkaloids, glycosides, flavonoid, terpenoids, saponins,and phenols. Therhizomes of Colocasia species are rich in starch and proteins,and are used in same manner as potato.They are somewhat more sweeter and easily cooked than potatoes. It is also a good sources ofcalcium and phosphorous .The tubers of Alocasia indica are also a good source of calcium andphosphorous with moderate amount of zinc, iron and magnesium .Its tuber has rich carbohydrate butmarginal protein content. The Dioscorea species also form a cheap source of carbohydrate and areextensively used by the hill tribes in the uncultivated part of certain parts of India .AmongDioscorea species ,the starch extracted from the tuber of Dioscorea alata are of large commercialused. They are poor in protein, calcium, and iron content but rich in vitamin b. The tuberous rootof Manihot esculenta crantz is grown as a subsidiary food crop in some part of india as it has highstarch and protein content with little or no hydrocyanic acids. Most of the edible tuberous cropsprovide essential nutritional value as a result it can give food security as well as supplement forcombating the malnutrition of the people for the future generation .

Dr RASHMI MUKHERJEEImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : RAJA N. L.

KHAN WOMEN'S COLLEGE [AUTONOMOUS] GOPE

PALACE, P.O.-VDYASAGAR UNIVERSITY, MIDNAPUR-

721102Designation : ASSISTANT

PROFESSOR & HEAD

Abstract: Oral lichen planus OLP) is an ongoing (chronic) inflammatory condition with whitish patches, red swollen tissues or open sores in the oral cavity. In fact, it is considered as one of the oral potential malignant disorders that highly affect a considerable size of Indian population. From epidemiological point of view it has been well established that oral consumption of tobacco and areca nut products is the major cause of OLP.

Early detection of cancer is the most significant step in its prevention. Clinico-pathological research is going on at a fast pace for developing better patient healthcare treatment modalities through improved diagnosis, prognosis, and surveillance by the use of biophotonic techniques. Vibrational spectroscopy has incredible prospective as it provides the “molecular fingerprint” which shows a glimpse of the sample’s biomolecular conformation and irregularities if any. This property is utilized in detecting various pathological conditions. Fourier transform infrared (FTIR) spectroscopy is a vibrational spectroscopic technique which allows rapid, high-throughput non-destructive analysis of a comprehensive sample types. They may be biofluids like serum, plasma, urine, saliva etc., or solid samples such as cells and tissues. The peaks (600–4000 cm?1) extracted from FTIR spectroscopy directly map to the vibration of a precise chemical bond or a functional group within the molecule giving exact inputs about the biochemical status. It has been efficiently used to distinguish several types of carcinomas as well as other diseases like dengue, diabetes, and scrapie.

FTIR spectroscopy in the region of 950–1800 cm?1 was utilized to establish the potential metabolic inconsistencies in serum samples as the variations in the carbohydrate, proteins (amino acid) and lipids are best reflected in this region. The peaks were identified taking the help of existing databases or published literature. There was significant alterations in the FTIR peaks which was further validated by biochemical tests. The result shows the sensitivity and specificity of the FTIR spectroscopic technique to simultaneously analyze different metabolites like carbohydrates, amino acids, fatty acids, lipids, proteins and polysaccharides within a very short span of time.

Ms Deblina GhoshImage Delegate ID Theme Details


Research



Werner Syndrome (WS) is a rare autosomal recessive genetic disease caused by a deficiency of a single gene known as WRN. Cellular WRN protein (WRNp) participates in multiple cellular metabolisms including replication, transcription and repair though the exact role of WRNp, which is responsible for premature aging and age associated diseases is not known yet. However posttranslational modulation of WRN has been shown to regulate its catalytic function and subcellular localization. Among the common post translational modifications phosphorylation, acetylations, sumoylations have been reported for WRN. WRN is phosphorylated at multiple ser/thr residue after DNA damage by DNA-PK (DNA dependent protein kinase) or cabl kinase. However exact role of phosphorylation of WRN in cellular response to DNA damage is not known yet. To understand the role of phosphorylation of WRN in cellular response to DNA damage, we have induced point mutation in the serine residues (Ser -Ala) of WRN at the position 440,467 (S440a and S467a) and transfect these plasmids in WRN mutant cells. Cellular response after DNA damage induced by etoposide was monitored by MTT assay, Comet assay and immuno-fluorescence microscopy. We identified that wild type WRN translocated to nucleoli after DNA damage but phospho mutants remain in the nucleoplasm. Role of phosphorylation at other residues in DNA damage response pathway is under investigation.

Mr arun kumar malaisamyImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Madurai

Kamaraj UniveristyDesignation : M.Sc

Biotechnology

Glutaryl-CoA dehydrogenase, encoded by the gene GCDH, plays a vital role in regulating lysine, tryptophan and hydroxylysine metabolism. Mutational defects in GCDH results in acquisition of citrate cycle, glutathione and butanoate pathway metabolites that are detected in urine, plasma and CSF, results in D2-hydroxyglutaricaciduria type-1. This study investigates clinical and mutational analysis of glutaricaciduria type-1 patients from Indian ethnicity. Bidirectional sequencing of the GCDH gene from 10 probands revealed two novel homozygous missense mutations (c.G505A: p.A169T and c.C528G: p.C176W), which are not detected elsewhere in any ethnicity. Pathogenicity of the novel mutations evaluated by in-silico predicted both the mutations to be "disease causing" by mutation taster tool. Additionally, c.G505A was predicted to hamper the normal splicing process. Polyphen also reported both the mutations as "probably damaging" with highest score of 0.9-1.0. Similarly, they were predicted to be deleterious by Provean with score of -3.752 (A169T) and -9.693 (p.C176W). It was also predicted using RNAfold server that c.505G>A results in an abrupt loss of the mRNA secondary structure. The loss of mRNA secondary structure can very well be correlated with the loss of function of the translated protein. Though, much change is not observed in B-factor and Poisson-Boltzmann electrostatistics, which acts as indicator of protein stability, the change in membrane protein orientation clearly reveals the actual pathogenicity of these mutations. To study the functional impairments of clinical mutations experimentally, the novel mutations identified will be introduced into this wild-type GCDH construct of pcDNA6.2/V5-GW by modified SDM protocol (Liu et al., 2008). The future prospective would be to characterize these novel mutations from Indian ethnicity in vitro and in vivo, which could serve as biomarkers for early diagnosis.

Keywords: Glutaric aciduria type-1; GCDH; Mutation; in silico; SDM; cloning. References: 1. Liu H, Naismith JH. An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol. BMC biotechnology. 2008; 8:91.

Ms JEYARAJ JEYAVANIImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Ayya Nadar

Janaki Ammal College,Centre for Research andPost Gratuate Department of Zoology,SivakasiDesignation : Research scholar

Abstract: Dengue vector is an important blood sucking Arthropods, capable of transmitting pathogens for many diseases like dengue fever, chikungunya, and viral encephalitis to humans in many parts of the tropics. Vectors control is an essential step towards the prevention of such harmful infections like dengue virus. In this context, the green synthesizes of silver nanoparticles from seaweed, Padina gymnospora for the dengue vector, Aedes aegypti and MDR human pathogens. The green synthesized nanoparticle characterized by UV, XRD, FT-IR, SEM confirms the nanoparticles were monodispersed and round in shape with an average size of 11.72nm. EDAX, patterns clearly illustrate the presence of AgClNPs,. Larvicidal activity of synthesized seaweed Pg-AgClPs is showing a very low concentration (3.61µg/ml) than the aqueous extract (21.61µg/ml). In addition, the Pg-AgClNPs also screened against the MDR pathogens (Methicillin-resistant Staphylococcus aureus, Vancomycin-Resistant Enterococcus faecium, Escherichia coli, Pseudomonas aeroginosa, and Candida albicans). Among these five MDR pathogens, the green synthesized Pg-AgClNPs showed maximum zone of inhibition on Candida albicans (31mm at 3mg/mL). Further, the hemolytic activity and eco-toxicity of silver nanoparticles analysed. Therefore, the susceptibility of different types of pathogens and dengue vector of Pg-AgClNPs observed in the present study to attributed to the presence of bioactive compounds.

Keywords: Silver chloride nanoparticle, Padina gymnospora, Anti-microbial activity, Eco-toxicity, Hemolytic activity, Larvicidal activity

Mr Gunaseelan SathaiahImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Madurai

Kamaraj UniveristyDesignation : M.Tech

Biotechnology

Phlorotannins from brown macroalgae Padina tetrastromatica: study of biological potential for non communicable diseases using C. elegans as an animal model Gunaseelan Sathaiah 1, Mohan Kumar Verma 1, Balasubramaniem Ashokkumar 2, and Perumal Varalakshmi 1* 1 Department of Molecular Microbiology, School of Biotechnology, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India 2 Department of Genetic Engineering, School of Biotechnology, Madurai Kamaraj University, Madurai 625021, Tamil Nadu, India * Tel: 08438420042, Email-id: [email protected] Marine brown seaweed are renowned for producing bioactive secondary metabolites such as phlorotannins. Phlorotannins are the polymer of the pholoroglucinol unit; it’s a phenolic compound with anti-inflammatory, anti-cancer and anti-AGE’s property (Yotsu et al. 2013). In this study, phlorotannin from brown macroalgae Padina tetrastromatica, were collected from the Gulf of mannar, Rameshwaram, and identified by microscopic observation. The compound was extracted and purified by using column chromatography. Extracted compound showed prominent inhibition of free radicals via reactive oxygen species (ROS) and nitric oxide scavenging activity in vitro. Further, effect of common food additives such as table sugar and monosodium glutamate which can be a major cause to develop chronic non-communicable disease like diabetes and cancer. To validate this C. elegans was as model organism to analyse the advanced glycated end products and stress responsive genes which are involved majorily in any chronic diseases like sod-1, daf-2 and daf-16 (Nussbaum et al. 2014). Phlorotannin (50ug/ml) when administered to stress induced C. elegans prominently decreased the expression of stress responsive genes which was confirmed by image intensity analysis of semi-quantitative PCR. Further, the traditional alternate sugars like palm sugar crystals and cane sugar could be analysed in comparison to table sugar. Keywords: Phlorotannin, C. elegans, ROS, daf-2. References: Nussbaum-Krammer CI, Morimoto RI. Caenorhabditis elegans as a model system for studying non-cell-autonomous mechanisms in protein-misfolding diseases. Disease models & mechanisms. 2014 Jan 1;7(1):31-9. Yotsu-Yamashita M, Kondo S, Segawa S, Lin YC, Toyohara H, Ito H, Konoki K, Cho Y, Uchida T. Isolation and structural determination of two novel phlorotannins from the brown alga Ecklonia kurome Okamura, and their radical scavenging activities. Marine drugs. 2013 Jan 18;11(1):165-83.

Ms Anupriya BhaktaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Patna

Women's College Designation : Student

Segmental regeneration was studied in the earthworm, Eisenia fetida by amputating the earthworm at 40th segment. Valproic acid, an HDAC inhibitor was used at the site of amputation in two concentrations 1mM & 2mM by Drop method. In another group of earthworm, healing of severed ventral nerve cord was studied by using Rapid Escape Response (RER) Assay. It was concluded that Valproic acid slowered the rate of segmental regeneration but promoted ventral nerve cord healing. The findings suggest the potential clinical application of valproic acid for the treatment of peripheral nerve injury in humans. The slowering action of valproic acid on segmental regeneration might be due to cell cycle arrest (an anti proliferative effect), suggesting its potential use in cancer therapy Keywords: Eisenia fetida, segmental regeneration, ventral nerve cord, valproic acid. References: 1. BBC 2003, A Point of View: Fly, Fish, Mouse, and Worm, BBC 2. Gottlicher M, Minucci S, 2017, The Embo Journal. 3. Park S K, Cho S J, Park S C 2013, 57, 165-169 4. Yasmin S, Kumari J, Kumari S, Tarannum N 2017, IRIS,7, 1-6 5. Sturzenbaum S R, Andre J, Kille P, Morgan A J 2009, 276, 789-797 6. Zhang Z et al 2017 7. Gilbert S F 2000, Development Biology, 6th Edition, Chapter 18 8. Bely A E, Sikes J M 2010, PNAS 107, 1464-1469 9. Drewes C D, Vining E P J, Zoran M 1998, 28, 1077-1089 10. Xiao N, Ge F, Edwards C A 2011, 31, 197-204

Dr Akanksha ChaturvediImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : National Center for Cell Science

Designation : Scientist D

Antibody responses are initiated by B cells that recognize and respond to foreign antigens throughclonally expressed antigen-specific B cell receptors (BCRs). Antigen binding to the BCR triggersboth BCR signaling and internalization. However, how internalization regulates signaling was notknown for the BCR and multiple other immune receptors. In a novel study, we demonstrated that theBCR signaling is compartmentalized. We showed that the BCR signaling is a dynamic process, whichbegins at the cell surface with the transient recruitment and phosphorylation of the early proximalsignaling kinases and continues as the BCR traffics into the cell with the sequential recruitmentand phosphorylation of downstream kinases. Moreover, BCR localization and trafficking are essentialfor optimal signaling. Interestingly, blocking endocytosis of the BCRs completely perturbs thespatiotemporal regulation of major signaling pathways leading to the dysregulation of genetranscription controlled by these pathways. This intracellular location of BCR not only serves toregulate the BCR signaling but also provides a platform where internalized BCR interacts with theintracellular Toll-like receptor (TLRs), in particular, TLR9. We showed that in resting B cells,TLR9 is localized in early endosomal compartments and signals from these compartments. BCRcrosslinking results in the relocalization of TLR9 to the autophagosome-like compartments into whichthe BCR is internalized and where synergistic signaling between BCR and TLR9 occurs. Besidesregulating BCR and TLR9 responses, intracellular location is also important in governing responsesto different TLR9 ligands

Ms Swati SinghImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Banasthali

VidyapithDesignation : Mtech

Background : Japanese encephalitis (JE) is an uncontrolled inflammatory disease of CNS and associated with progressive neuronal cell death and dysfunction. However the underlying molecular mechanisms is not clear. Microglia are the resident immune cells of CNS and are important for viral clearance and modulation of neurotoxicity of viral infection diseases. CCR2 is an chemokine receptors that regulate the responses of both microglia/infilterating macrophage during inflammation in CNS. Method: In the current study, we used antagonist molecule of CCR2; RS102895, to understand the role of CCR2 receptor in JE viral encephalitis-associated neuro-inflammation and neuro-degeneration, using the JE virus model of microglia (Bv2) and encephalitis in Balb/c mice. Expression of microglia markers IBA1 and polyubiquitin was analysed. Result: Our result demonstrated that Bv2 microglia cell proliferation and cell size significantly increases at 24hr and 72hr and shows altered activation phenotype after JE viral infection. Furthermore, we show that movement of microglia is also affected and shows more elongated phenotype and form the trail morphology, end-to-end alignment, in scratch analysis at 24hr followed by JE viral infection. Our result show that CCR2 inhibition plays key role in modulation of microglia activation phenotype in Bv2 microglia upon infection. Furthermore, by using in vivo model of JE viral infection, we show that, RS102895 treatment, significantly reduces microglia activation and neuronal cell death in cortical tissue of JE viral infected mice in compare to control animals. Conclusion:The following finding suggest that CCR2 inhibition could be an important therapeutic target for the modulation of microglia activation phenotype and its mediated neurotoxicity pathologies followed by JE viral infection.

Dr Biswarup BasuImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Chittaranjan

National Cancer InstituteDesignation : Senior

Scientist

As an attempt to overcome the challenge of targeted drug delivery and efficacy , two batches of a polyphenolic phyto-constituent are prepared in the present investigation. The polymer used for the preparation of nanoparticles is chitosan using ionotropic gelation method. Among the two batches, one batch was coated with tween 80 and other was kept intact. The developed nanoformulation were analyzed using Differential scanning calorimetry (DSC) and Fourier transform infra-red spectroscopy (FTIR) after lyophillization taking mannitol as cryo-protectant. Also, their particle size, zeta potential, polydispersity index, drug entrapment, morphology and in vitro drug release are evaluated using suitable instruments. We applied this nanoformulations in both coated & uncoated form in vitro with promosing results. To find efficacy on vivo, sarcoma-180 induced solid tumor bearing mice model was prepared.We found that this nanoformulation is able to reduce the tumor volume as well as increased animal survivability. We observed that the tween 80 coated polyphenol gives better efficacy compared to pure phyto-constituent.

Dr RAHUL BHAGATImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Govt. Institute

of Science, AurangabadDesignation : Assistant

Professor

Abstract Microbial enzymes play a crucial role as a metabolic catalyst and have great importance in the development of industrial bioprocesses. The microbial enzymes applicable in the Food Industry, Brewing Industry, the Agricultural Industry, Laundry Industry, etc. Microbial Inulinase is used for the production of fructose syrup and fructooligosaccharides which are important ingredients in the food and pharmaceutical industry. The study was aimed to isolate novel microbes for industrially important inulinase enzyme production. The Inulinases producers were isolated from rhizospheric soil of inulin containing plants. The soil samples were collected from the rhizosphere of the Allium sativum (Garlic) and Allium cepa L (Onion) plants from the fields of the Aurangabad region (Maharashtra). All the bacterial isolates were screened for inulinase production. A total of 04 isolates were obtained showing enzyme activity. The enzyme produced in submerged culture using a basal medium added with inulin. The crude enzyme was partially purified using ammonium sulfate precipitation and dialysis. The activity of Inulinase in terms of degradation of the inulin substrate into fructose was performed by the DNSA method. The kinetic properties of the enzyme were assayed by parameters such as pH, temperature and substrate concentration. Inulinase enzyme was found to be stable at 30 –60 °C and the optimum temperature was at 50 °C. The enzyme was stable at pH 4.0–8.0 and the optimum pH was at 8. Bacterial isolates reported in this study can be exploited for industrial-scale production of inulinase and natural resources like inulin containing plant parts can be used as raw material for the cultivation of microbial biomass. (Keywords - Inulin, Inulinase, Rhizosphere, Enzyme activity)

Mr BIRAT RAJA PADHANImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : PRUTHIBI

SCIENCE CLUBDesignation : SCIENCE

COMMUNICATOR

DAMaN and LLIN- successful tools for Malaria elimination Birat Raja Padhan1,E kariali2, P Nanda3,P Bhoi4, M.M Pradhan5,DS Naik6 1. Sambalpur University,Jyoti Vihar,Burla.Sambalpur/NVBDCP,Jharsuguda,,[email protected] 2. Sambalpur University,Sambalpur,3.DN Govt. College,Itanagar,4.BB Medical College,Bolangir,5.nvbdcp,Boudh,odisha,6.Pruthibi Science Club,Benkamura Contact Author’s e-mail address: [email protected],[email protected]

Abstract: Malaria is a local and focal disease. Odisha is highly malaria endemic states with 46 million populations are at risk of infection. Prevalence of Anopheles mosquito vector resulted in malaria transmission in different parts of the state. The Plasmodium falciparum infection rate is very high.i.e-93% in 2012 and 81% in 2018.The falciparum malaria is dangerous and it needs proper management in severe form to avoid mortality. Asymptomatic Malaria cases(No fever but they test positive for malaria) is one of an important silent reservoirs for Malaria. The state Government envisaged to launch an innovative programme in all endemic areas of state-DAMaN (Durgama Anchalare Malaria Nirakarana) to fight asymptomatic reservoirs. DAMaN camps conducted twice in a year. First phase prior to monsoon during April-May and second phase during September-October and third phase during January-February. In Sundargarh district 1.1 billion LLIN has been saturated to 2.2 billion population in contiguous manner. After the successful intervention of LLIN and DAMaN the case load of Malaria reduced 83% and 67% in 2018 and 2019(Up to Aug 19). All the population of remote and plain areas protected by LLINs and asymptomatic reservoir got cleared in all villages with routine approaches. Due to proper implementation and supportive supervision at village level, malaria transmission could be halted in very short span of time.

Ms Priyanka SenguptaImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Saha Institute

of Nuclear PhysicsDesignation : Junior

Research fellow

Abstract: Alzheimer’s disease (AD) is a multifactorial complex progressive neurodegenerative disease. The key attribute involves severe memory loss which is invariably followed by a steady decline in higher cognitive abilities. Neuronal death in such a scenario involves hyperactivation of neurons and aberrant cell cycle re-entry in the initial phase of degeneration. The study tries to trace back the origin of this vicious cascade of Amyloid ? oligomer aggregation and tau phosphorylation which are the major hallmarks of this disease. It all begins with increase in the gamma secretase mediated cleavage of amyloid precursor protein APP to generate amyloid ? fragment, and APP intracellular domain (AICD). Amyloid ? is generated normally in neuronal cells at higher levels than other cells yet they oligomerize under disease conditions as their production increases drastically. This triggers signaling cascades through unknown mechanisms since interaction of the former with membrane receptors is poorly understood. Alzheimer’s disease due to its complex nature thus remains an elusive mystery despite substantial work in the field. To ensure better understanding of the mechanics of disease initiation, the changes in Akt and MAP kinase pathways with respect to introduction of Amyloid ? and AICD was studied. These two pathways play major roles in tau phosphorylation and in ensuring survival in initial phase of disease progression. To assess the levels, cell culture assays were performed with A? oligomers and AICD construct in cell model. To compare the scenario with Alzheimer’s disease, a cell based model of the same was also developed. The comparative analysis was performed through western blotting and RT PCR assays. In Alzheimer’s disease based cell model, the levels of Akt and MAP kinase increases which was previously reported as well. However, in AICD transfected cells and A? treated cells, the scenario was contrasting. In the former, the pathways under investigation are upregulated whereas in the later they are downregulated. AICD possibly alters their rate of phosphorylation, as expression variations across control and experimental samples appears to be low. Such an event further bolsters the neuroprotective action of AICD and sheds light on the disease mechanism. In conclusion, the study essentially indicates that AICD is a major peptide that determines cellular fate. It essentially pushes cell towards proliferative pathways that aids survival but also in turn triggers tau phosphorylation that leads to neurodegeneration.

Ms SUMAN THAKURImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Pt. JNM

MEDICAL COLLEGEDesignation : STUDENT

Fungi are predominant in the environments. They play important roles in the health of plants,animals, and humans, and in broad ecosystem functions. Thus, having an efficient species-levelidentification system could significantly enhance our ability to treat fungal diseases and tomonitor its distributions. DNA barcoding is a potent approach for rapid identification of fungalspecimens, generating novel species hypothesis, and guiding biodiversity and ecological studies. Itis the use of short standardised segments of the genome for identification of species in all thekingdoms of life. It can be relatively straightforward (sample collection, isolation of DNA,amplification of the barcoding gene and finally sequencing and analyzing the results). The purposeof this study to promote fungal DNA barcoding and to generate the efficient mointering system.Candida spp. are opportunistic organisms. It is the major cause of mortality in bothimmunecompromised and critically ill patients. Sequence based identification method was comparedwith by traditional methods like carbohydrate assimilation tests. DNA is extracted from the sampleand the barcode portion of the nuclear (Internal transcribed spacer) ITS gene is amplified by PCRusing fungal specific ITS primers then, amplified sequence is submitted for sequencing in one orboth directions. ITS region has the highest probability of successful identification for thebroadest range of fungi. For barcoding, the BLAST algorithm will attempt to match the primersequences to the DNA sequences stored in their database. It can quickly identify any close matchesto our sequence in database, generating a phylogenetic tree from DNA sequences derived from relatedspecies and can allow to draw inferences about how all these species may be related. The GenBank isdesigned to provide an encourage access to the most up to date and comprehensive DNA sequenceinformation, with the help of this we can get the informations related to our sample sequences. Thistechnique will benefit a variety of projects by providing fast and cost effective speciesidentification. Thus, this study is to developed a standardized DNA sequence-based approach for theaccurate and timely identification of Candida species instead of long identification procedures, andcan aid to generate future card tests for species specific disease identification.

Ms Vijaylakshmi JainImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Sam

Higginbottom Univesity of Agriculture Technology and

Sciences Designation : Research

scholar

The multidrug resistivity of opportunistic microorganisms is still of major concern. Despiteimprovements and advancement in the antifungal therapies, the development of the new competent drugwith lesser side effects is still needed to be achieved1. Antimicrobial peptides of cationic andamphipathic nature, isolated from various arthropods and molluscs, were considered to be promisingcandidates with no side effects towards eukaryotes. This study is first to report the antifungalnature of proteins purified from the hemolymph of Zygogramma bicolorata, immunized with Micrococcuslutes (MTCC 106) and Escherichia coli (MTCC 443). Extracted immunized hemolymph was assayed forantimicrobial sensitivity against pathogenic fungus Candida albicans (ITCC 4718) causing candidiasisand Aspergillus niger (ITCC 5479) causing otomycosis by disc diffusion method2. The crude hemolymphextract was separated and purified by low-pressure size exclusion chromatography using a SephadexG-50 column (150mm × 20mm). Protein estimation was performed by Lowry’s method followed by theassessment of antifungal activity. It was found that six (Fraction 7,9,11,13,15 and, 17) out ofthirty fractions exhibited activity against the test organism. SDS-PAGE elucidates that fractionsaccommodate high molecular weight proteins ranging from 15 kDa to 180kDa. Subsequently, fraction 9with the highest antifungal activity was further was analyzed and sequenced by LC-MS/MS. It reported10 proteins that differ considerably on amino acid sequences, isoelectric point values, andantimicrobial activity spectrum. Being MDR in dire matter, the efficacy of the drug is momentous.Thus, the paper demonstrates the purification and characterization of 10 proteins from the hemolymphof immune challenged Z. bicolorata with vivid amino acid sequences and antimicrobial activityspectrum. The findings open new avenues for future studies in the evolution of essential proteins ordrugs against fungal infections.

Mr ABHISEKH SUBBAImage Delegate ID Theme Details


Research



Scholar

Mosquito borne diseases pose a major threat to human health in India. Due to lack of propermedication for these diseases vector control is the best alternative method. Moreover, vectorcontrol is facing a huge challenge due to insecticide resistance development in them. Phytochemicalsseem to have a future scope in eco-friendly vector management programs. Therefore, this study wasperformed to examine oviposition deterrent activity, ovicidal activity and larvicidal activity ofdifferent solvent extracts of Zingiber montanum, (J.Koenig) Link ex A.Dietr. rhizome, collected fromthe hill region of Darjeeling District of West Bengal, against Culex quinquefasciatus. WHOguidelines 2013 was followed for all the three bioassays with few modifications. Larval mortalitywas observed after 24hrs, 48hrs and 72hrs. Almost all the solvent extract of the plant showed someamount of mortality. Highest mortality was seen in n-hexane extract of the plant with the followingLC50 values - LC50/24hrs=52.57ppm; LC50/48hrs=17.89ppm; LC50/72hrs=5.38ppm. Bioassays foroviposition deterrent activity and ovicidal activity of the most potent extract i.e., n-hexaneextract, was conducted at different concentration. Oviposition activity index (OAI) at 5ppm and10ppm was -0.81 and -0.71ppm, respectively, and -1 at 50ppm and above. This shows clear evidence ofdeterrent activity of the extract. Besides, no eggs hatched at 50ppm and higher dose of plantextract. To understand the phytochemical composition GC-MS of all the extracts was conducted.Presence of Terpinen-4-ol was conformed in n-hexane (11.21%) and diethylether extract (4.99%);cinnamaldehyde (4.60%) and ?-sequiphellandrene (3.60%) in n-hexane and eugenol (2.66%) indiethylether extract. The outcome of the present study revealed that the rhizome extract of Zingibermontanum possess great potential to be used as a vector control agent.

Mr Parag ManeImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : Atul LtdDesignation : Assitant

Manager

We present an alternative bioprocess for bacteriophages involving room temperature coprecipitationof an aqueous mixture of phage (Siphoviridae) and a crystallizable carrier (glutamine or glycine) inexcess of water miscible organic solvent (isopropanol or isobutanol). The resultant suspension ofphage-coated microcrystals can be harvested by filtration and the residual solvent removed rapidlyby air-drying at a relative humidity of 75%. Albumin or trehalose added at 5% w/w of the crystallinecarrier provide for better stabilization of the phage during co-precipitation. Free-flowing drypowders generated from an aqueous solution of phage (?13 log(10) pfu/mL) can be reconstituted in thesame aqueous volume to a phage titer of almost 10 log(10) pfu/mL; high enough to permit subsequentformulation steps following bioprocessing. The phage-coated microcrystals remain partially stable atroom temperature for at least one month, which compares favorably with phage immobilized intopolyester microcarriers or lyophilized with excipient (1-5% polyethylene glycol 6000 or 0.1-0.5 Msucrose). We anticipate that this bioprocessing technique will have application to other phagefamilies as required for the development of phage therapies.

Dr ANKUR KULSHRESHTHAImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : csir-igib

Designation : DST-INSPIRE Faculty

With the advent of the era of synthetic biology and bioengineering, there has been a great need to be able to introduce more and more genetic parts in an organism. However, it has been observed that the efficiency of the introduction of genetic material goes down exponentially with the increase in the size of the vector used. At the same time using multiple vectors is also not feasible as it makes difficult to control the required stoichiometric concentrations of various components. One solution to mitigate this bottleneck is the use of self-cleaving peptides, that allow co-translational production of multiple proteins, which are then cleaved on their own at the site of self-cleaving peptides, hence allowing them to function independently while keeping desired and coupled concentrations. There already have few documented self-cleaving peptides in the literature that have been derived from viruses, however, there is still a need for more efficient and diverse self-cleaving peptides to increase their repertoire and make available more tools at the disposal of synthetic biologists. To achieve this, we've postulated a fret-pair based methodology to identify several novel-self cleaving peptides. We present some of our preliminary work in this regard.

Dr ipsita pal bhowmickImage Delegate ID Theme Details


Research

Category : BiologyOrganisation : ICMR-NE

RMRC DibrugarhDesignation : Scientist C

Malaria being a highly local and focal disease, especially in some parts of the country like North east, may be better controlled by identifying and acting upon the local risk factors leading to the hot foci, in order to reach the final aim of elimination, rather than adopting an uniform intervention plan for whole country. North Eastern seven States with 12%, of P. falciparum cases and 25% of malaria deaths as per 2018 data, with similar trend over past years. Highly heterologous nature of malaria burden sharing is more evident when district and PHC level malaria data analysis is done to show while many areas of NE have zero or 15 API and they are located mainly in remote tribal areas of foothill forest and forest fringe areas. Further microlevel analysis with some sub centre and villages has identified hot foci areas in subcentre and village level. Our studies are in the process of identification of several risk factors leading to high and persistent malaria foci in these tribal regions and taken initiatives to design strategies on customized and targeted intervention to accelerate malaria control, which include development of an app in collaboration with NESAC Shillong for real time mobile surveiilance for malaria detection and drug compliance, adherence, vector control measurement.

Ms PRITI RAJPUTImage Delegate ID Theme Details


Research

Category : Applied Engineering

Organisation : j and k govt.Designation : statistical

officer

Living tissue inheritably has the ability of self-healing on getting wounded or misaligned. Thehealing mechanism starts within seconds of getting injured. The damaged blood vessels send a signalto the blood cell platelets that race together and form a clot to prevent further blood loss. Theclots turn to scab with time. The blood vessels open to allow fresh nutrients and oxygen into thewound that speeds healing and white blood vessels joins in to fight infection. Oxygen rich red bloodcells arrives at the wound site to build up the damaged tissue. With time the tissue healscompletely and is same as it was before. Body’s mechanism takes a fixed time to heal the wounddepending upon the conditioning of the wound and immune system. Sometimes it takes more than a yearto heal the wound and in that case manmade modes are required to heal the wound at a pace. Bandagesare a mean to aid healing. The traditional mechanisms of healing the wounds involve examining it byremoving the bandages regularly that hinders the healing mechanism. With advancement in technology,the traditional techniques are being replaced by smart methods of wound management. Researchersthroughout the world are working on smart bandage technology. The current fast and technologicalworld demands a bandage that needs to be monitored at home for spread of infection or restorativeprocess. Different bandages have been under development in various research institutes across theglobe. The smart bandages react to the varying level of oxygen, pH, moisture, or infection at thewounded area. It’s great relief to the wounded soldiers in the battle field as it helps to monitorthe wound in the absence of doctors. The paper presents a review of various smart bandages developedby different researchers.

Mr SOUMYA DEBASHIS DASImage Delegate ID Theme Details


Research


Organisation : UNIVERSITY OF EDINBURGH


Application of MPPT Charge Controller in Optical Wireless Information & Power Transfer

Soumya Debashis Das M-Tech Scholar Department of EE Veer Surendra Sai University of Technology, Burla [email protected]

Due to requirement for low cost and modest data rates small wireless communication cells (SCs) make good sites for the early introduction of combined wireless backhaul communication and power transfer. The three basic concepts to be illustrated in this paper are optical wireless power transfer (OWPT), solar energy harvesting (EH) and electrochemical storage. Small Cells are defined as the moderately powered radio access nodes that enable data communication to consumers within areas ranging from a few meters to a few kilometers. The choice of solar cell material will be discussed as this has a significant impact on both energy harvesting and communication bandwidth. Should the cost of deploying OWPT be decreased, non- renewable grid power connections will not be needed, leading to significant cost savings during wireless network deployment. The core of this paper is the characterization of the optical properties of Laser Diodes (LDs), in particular, the use of VCSELs for simultaneous data and power transmission. A 1550nm VCSEL is used in a laser driver circuit showing improved bandwidth. Simultaneously, there is an optical power transfer averaging up to 5mW from the board. Photovoltaic (PV) Panels are used as a receiver to convert the transmitted optical power into electricity and data. The use of the concept of maximum power point tracking (MPPT) plays a significant role in the efficient electrochemical storage of the PV panels energy. The integration of all the three modules, optical wireless power transfer, energy harvesting, and the electrochemical storage is demonstrated in an end-to-end system with good efficiency. Finally, the same power stored in the battery powers the entire solar LiFi receiver board and the laser transmitter.

Mr Prakanshu SrivastavaImage Delegate ID Theme Details


Research


Organisation : PSIT College of Engineering


The basic concepts and initial prototype of a word-gesture keyboard are discussed. The idea behindthis device to write words or Characters on Making Gestures in the Air. We designed a Pen lookingDevice to write words/Character in the Monitor Screen. It works on wired and wireless bothTechnology. It is based on IoT(Internet of Things) and Machine Learning(ML). In using a word-gesturekeyboard, the production of movements increasingly changes from focusing on individual letters toconnecting multiple letters into a word gesture. Conceptually, gesture recognition is done byidentifying the word which has the highest probability given the user's gesture.

Mr Saurabh ShekharImage Delegate ID Theme Details


Research


Organisation : CSIR-National Metallurgical LaboratoryDesignation : Scientist

Potassium is one of the basic macronutrients along with nitrogen and phosphorus which is essentialto maintain and expand quality food production. Currently, it is being produced from undergroundevaporative beds or recovered from natural sea brine solution; deposited in Canada, Russia, Belarus,Chile, USA and Germany. Thus, there exists a strong dependence on these countries for the import ofpotash fertilizer. Rising price, limited geographical availability of these conventional sources andincreasing demand has stimulated a search for alternative potash containing sources. Glauconite is anatural occurring iron-rich, heterogeneous, phyllosilicate mineral containing around 4-8% of K2O,thus, considered as a promising alternative sourcefor potash fertilizer. Processes with potashrecovery alone, from low grade reserve like glauconite may not be economical. Therefore, asustainable process is developed for the recovery of potash fertilizer and iron oxides from twodifferent glauconite sample. Potassium is a part of stable structure (dioctahedral T-O-T) inglauconite and locked in alumino-silicate matrix. In order to break the matrix and maximizepotassium dissolution, the glauconite sample containing 5-6% K2O and 10.75-31.9% Fe2O3was subjectedto pre-treatment followed by acid leaching. The leach liquor containing more than 95% recovery ofiron and potash, whichwas further treated through precipitation and solvent extraction route forrecovery of final products in form of potassium chloride, magnetite and hematite. Different processparameters were studied and optimized for the development of complete flow sheet.

Dr Yogender Singh YadavImage Delegate ID Theme Details


Research


Organisation : Lala Lajpat Rai University of Veterinary

and Animal Sciences (LUVAS)


Electrodepositing of silver quantum dot with graphene oxide sensor was prepared for detetermination of H2O2 in milk. The nano composite were immobilised on gold electrode surfaces using an organic linker, silver quantum dots were prepared by chemical method and composite with graphene oxide by ultrasonication process. The properties of Ag/GO were characterized by scanning electron microscopy, energy dispersive X-ray, X-ray photoelectron spectroscopy and Raman spectroscopy. The electrocatalytic reduction of H2O2 was examined using various techniques such as cyclic voltammetry (CV), chronoamperometry and amperometry .The sensor was effective in detecting H2O2 in a Phosphate-Buffered Saline (PBS) solution and in milk samples. The Ag/GO hybrid electrode had an excellent electrochemical property with superb electrocatalytic activity and large electrochemical active surface area, flexibility and high stability. The linear ranges of the as-prepared sensor for H2O2 detection were divided into two linear sections: 0.2 µmol/L to 2.0 mmol/L and 2.5 to 9.5 mmol/L with a detection limit of 100 nmol/L (S/N = 3) and a response time of less than 5 seconds. The results indicated that the developed assay and commercially available kit methods were highly interrelated. Keywords: Gold electrode; hydrogen peroxide sensor; electocatalysis; Ag quantum dot

Dr Paramita GuhaImage Delegate ID Theme Details


Research


Organisation : CSIR-Central Scientific Instruments

OrganisationDesignation : Scientist

Background: Forests are the nature’s energy harvesters converting solar energy to food, and air. Latest surveys show that the forest cover in India is 19.27% and decreasing rapidly. One major reason for this rapid reduction is forest fires which are caused by natural means and human interaction. Inability to detect such forest fires and extinguish it at the early stages has caused uncontrollable fires that destroyed the environment and property which was immeasurable. Hence, it is prudent to device methods to detect and extinguish fires before it spreads and cause extensive damage to the environment and property. Keeping this aim in mind we have decided to tackle the broader problem of early detection of forest fires and distinguish/control of such fires before they become uncontrollable. Methods: Wireless sensor nodes with IR sensor arrays, gas sensors, ambient temperature sensors, GSM communication modules, solar panels are being placed in fire prone areas of forests and networking them to detect abnormal variations in different parameters. WSN network is utilized for sending sensor data to the base station. If a forest fire initiates, these nodes will inform the base station where the later will use its intelligent decision-making algorithms to decide the presence of fire. After the fire is located, a signal is sent to the ground robots which will reach there to extinguish the same. In this work, we have developed systems to localize the fires and robots are designed to extinguish them. Field trials are under progress. Results and Conclusion: In this paper, we have developed an efficient device based on WSN techniques to detect the forest fire in early stage. Four nodes are developed and data sent wirelessly to base station which sends signal to ground robots for further action. Acknowledgment: Authors are thankful to DST, India for sponsoring this project.

Mr Muhammed Niyas K PImage Delegate ID Theme Details


Research


Organisation : central university of tamilnadu

Designation : research scholar

Dementia is a common mental illness seen among aged people. Doctors face difficulty in finding out the dementia patients. Finding out dementia patients is vital in better health care planning of aged people. In this paper, a comparative study of various machine learning algorithms for the classification of demented, non-demented, non demented to demented converters are performed. Our results suggest that 1-Nearest Neighbour algorithm performs better than Logistic Regression, Decision tree and Ensemble based majority voting classifiers with an average accuracy .

Mr Animesh DattaImage Delegate ID Theme Details


Research

Category : Applied EngineeringOrganisation : NATIONAL INSTITUTE

OF TECHNOLOGY,DURGAPURDesignation : 4th Year Undergraduate

Student

The synaptic functionality of the brain acts as an inspiration for the implementation of deep neuralnetworks and deep learning algorithms in an energy-efficient manner. Non-volatile memory deviceswith multiple resistance states can be used as a storage and computing element for the weight updatemechanism resulting in low-cost computations. The current-voltage (I-V) hysteresis property ofhybrid halide perovskites can be exploited efficiently for their implementation in these resistiveswitching devices. Here we use an all-inorganic perovskite CsPbBr3 as a prototype material forexploring light-stimulated ionic conductivity as an additional mechanism for controlling resistiveswitching since they provide better stability than organic halide perovskites. In this study,electronic structure calculations were performed using density functional theory implemented in theVienna ab initio simulation package (VASP) with projector augmented wave (PAW) potentials. Theclimbed nudged elastic method (NEB) was used to determine the minimum energy path between theinitial and final state of the CsPbBr3 structure. Using the optimized image structures in the groundstate the energy path for the excited state for the CsPbBr3 under laser radiation was estimated. Theresults obtained show a significant decrease in the activation energy of bromine migration underoptical illumination. This implies a faster switching speed and lowers set electric field leading tolower power consumption. The results also have shown an interesting transition from the indirectbandgap to the direct bandgap due to the migration of bromine in the CsPbBr3 structure, which can beattributed to phonon emission, which also has a role to play in the lowering of migration energy ofbromine in the excited state. This opens an interesting avenue for RRAM devices where the switchingis controlled not only by the duration/intensity of potentiation pulses but also by illumination.

Mr MIJANUR RAHIMImage Delegate ID Theme Details


Research


Organisation : Aliah University

Designation : PhD Scholar (Engineering)

The performance analysis of combinational dispersion compensation scheme using Dispersion Compensation Fiber (DCF) and Fiber Bragg Grating (FBG) for a 8x10 Gbps WDM system has carried out in this paper. In high data rate optical communication system like DWDM system combinational dispersion compensation scheme is essential for smooth amplification of the signal over wide range of wavelengths. A configuration consisting of 8 channels WDM system consist 0.8nm channel spacing for 1552.52- 1546.91 nm wavelength with NRZ pulses for the data rates of 10Gbps is modelled, simulated and analyzed at 100-1000 km transmission distance using combinational dispersion compensation scheme. The performance characteristics in terms of eye diagrams, Q-factors, gains, output power, eye height, threshold of received signals are obtained and analyzed for different system configurations. A comparison between mentioned schemes and earlier schemes are performed in this paper. Optisystem 13.0 is used for the simulation of this proposed model.

Key Words : WDM System, Dispersion Compensation, DCF, FBG.

Ms Shivani PandeyImage Delegate ID Theme Details


Research


Organisation : COUNCIL OF SCIENTIFIC AND

INDUSTRIAL RESEARCHDesignation : Research

Scholar

Chemical contaminants such as fluoride and arsenic do not give any coloration to the water and henceno efforts are made to remove or reduce the concentration of the same, which leads to serious healthhazards. Excess of arsenic and fluoride are very harmful and these are responsible for manydiseases. Every year in India itself 37.7 million people are suffering from serious health hazardsdue to waterborne diseases and nearly 1.5 million children are estimated to die due to watertransmitted diseases. Arsenic and fluoride gets into the human body through drinking water as wellas eating food that has been contaminated with arsenic. In this paper, the design and development ofa cost effective sensor that detect arsenic and fluoride in water is carried out. Advanced materialwill be developed from waste material for sensor development which reduces the response time as wellas the size and cost of the sensor. At present, there is acute need for sensor that ensures safetyof drinking water systems. Advanced sensor is designed to present a simple face to host structurevia a digital interface. In this study, artificial intelligence techniques could be applied for theanalysis of the water quality data and its reliability.

Ms Sandeepika sharmaImage Delegate ID Theme Details


Research


Organisation : NIT Kurukshetra

Designation : research scholar

With rapid development in wireless communication, Intelligent Transportations System (ITS) has received significant attention. This system delivers various social and economic benefits including efficient traffic management, lesser prone to accidents, reduced air pollution and enabling of the unmanned driving for enhanced leisure. ITS is enabled through real-time communication either Vehicle-to-Vehicle (V2V) or Vehicle-to-Infrastructure (V2I) modes of intra-infrastructure communication. LTE-V2V is seen as a major technology towards ITS implementation. Here we discuss various autonomous resource selection (RS) techniques available for Mode-4 V2V communication under LTE-A network. An enhanced RS scheme based on exponential averaging in time domain and normalized scaling in frequency domain is being proposed. Simulation results shows the efficacy of the proposed algorithm in terms of packet reception ratio (PRR), error rate and update delay. Proposed scheme enables low latency transmission of cooperative awareness messages (CAMs) while maintaing high PRR and low error rate. Cooperative awareness intended for intelligent traffic systemrequires accurate, reliable and ultra-low latency communication. For evaluation, error rate, packet reception ratio (PRR) and update delay are used as the performance metrics.

Mr Debanjan KonarImage Delegate ID Theme Details


Research


Organisation : Sikkim Manipal Institute of

TechnologyDesignation : Assistant

Professor

A novel integrated quantum inspired self-supervised frame-work for fully automated Brain MR image segmentation to obviate the challenges faced by deeply supervised Convolutional Neural Networks (CNN). In sheer contrast to automated brain tumor segmentation, CNN based approaches suffer due to lack of image specific adaptation and expert domain image analysts for labeling of the training images. It also suffers from huge time and space complexity. In addition, deep learning based technologies require extensive computational resources to perform the training. Owing to high performance computing requirement for implementation of deep learning technologies on MR images with wide variation of gray scales, it is always called for fully automatic segmentation of brain tumor region of interest on MR images in cost effective portable devices, mobile devices and in cloud without incorporating any high-performance Graphics Processing Unit (GPU).

The primary focus of the suggested work is to develop a cost effective pattern identi?cation integrated self-supervised neural network framework referred as Quantum-Inspired Self-supervised Neural Network (QISNet) architecture embedded with Quantum-Inspired Multi-level Sigmoidal (QIMSig) activation function targeting fully automated segmentation of brain tumors without any external supervision in portable devices, mobile devices and cloud in real time. The proposed QISNet comprises with three layers (input, intermediate and output layers) of neurons represented as qubits and inter-connected through second order based topology. The proposed neural network architecture incorporates the mechanism of adaptive thresholding (represented by rotation gates) applicable for multi-level segmentation of MR images. The intermediate/hidden and output layer of the network framework are inter-connected through counter propagation of quantum states and MR image pixels (quantum bits) are self-organized in between these two layers without any external supervision or training. Quantum observation is carried out at the end to obtain the segmented tumor from the superposition of quantum states collapse on interaction with the environment.

Dr GOKULAKRISHNAN PARANDHAMANImage Delegate ID Theme Details


Research

Category : Applied EngineeringOrganisation : PSNA

COLLEGE OF ENGINEERING AND TECHNOLOGY

Designation : ASSOCIATE PROFESSOR

Intelligent Transportation System is a promising area of research where more improvements need to be done in India. Vehicular Ad-hoc Network is an emerging technology that can be applied to find viable solutions in Road Transportation Systems. An Intelligent Road Accident Prevention (IRAP) framework is proposed based on Vehicular Backbone Network (VBN) structure is attempted using Vehicular Ad-hoc Network (VANET) to improve the efficiency of Traffic and Transportation in Indian Express Highways. The IRAP framework aims to prevent the vehicles from accidents in the highways and reduces the casualty and death rates. Once IRAP framework predicts the possibility of an abnormal event (i.e. an emergency situation) in advance, IRAP initiates an express highway road accident prevention strategy. The IRAP framework does the following: (i) a Road Side Unit (RSU) builds a Prediction Report (PR) based on the vehicle’s status and traffic scenario in the highway (ii) RSU generates an Emergency Message (EM) based on PR (iii) the RSU forms a VBN structure and (iv) the RSU disseminates the EM to the vehicles that travels in High Risk Area (HRA) and has a high possibility to meet with an accident. The IRAP framework improves the performance of EM dissemination by increase in notification and decrease in end-to-end delay. The IRAP framework attempts to reduce the cost incurred towards the infrastructure setup by using the VBN structure. The IRAP framework with VBN structure improves the notification by 21 percent and end-to-end delay by 17.48 percent for a vehicle density of 240 vehicles in 500 meters.

Keywords: Vehicular Backbone Network, Vehicular Ad-hoc Network, Road Side Unit, Emergency Message, notification, dissemination, end-to-end delay, High Risk Zone.

Dr Ayona ChakrabortyImage Delegate ID Theme Details


Research




Major limitation of planar (microstrip) antenna is its inability to provide omni-directionalradiation patterns. Base station trans-receiver antennas for mobile communication requireomni-directional radiation patterns. In this report an efficient four looped modified and reactivelyloaded clover arranged omni-directional polarization agile (circularly polarized in lower band an ddual polarized in higher band) wire antenna has been presented for dual band viz. mobilecommunication and WiMAX frequency operations. Wire antennas are the most basic antenna designstructures since the inception of antenna communication. In the range of wire antennas, dipole orfolded dipole is the simplest among all others [1] where matching with the input feed is a majordisadvantage. To overcome this , lately, a special efficient extension of dipole configurationcloverleaf loop arrangement resembling the petals of a three or four-leaf c lover is becomingpopular. From quite some time, planar antennas (based on microstrip structures) have been a subjectof extensive research, while they have been highly functional in recent times; they provideessentially hemispherical/directional patterns, which is not very useful as broadcasting antennasfrom base stations. Whereas, the proposed antenna (or its array) with polarization diversity,omni-directional pattern radiating more or less equal power in all directions is useful for radio-broadcast, walkie -talkie, police vehicles etc. In this report, a unique four-looped clover arrangedwire antenna giving rise to essentially toroid-shaped omni- directional radiation pattern has beenreported, with an intention to overcome the above mentioned difficulty. The antenna exhibits dualfrequency bands (2.18GHz-2.57GHz & 3.8GHz-4.3GHz of operation), both useful for mobilecommunication, WiMAX or satellite telephony. In the lower frequency band circular polarization isobtained whereas in the higher frequency band the antenna offers dual polarization. The arrangementof the antenna is compact in nature and can be visualized as four folded dipoles attached in asingle 3600 azimuthal configuration. The antenna being metallic it is robust in nature which can bearrayed for higher gain and mounted on the sector panels at base-stations for satellite or mobilecommunications.

Mr Keshar Kumar LuitelImage Delegate ID Theme Details


Research


Organisation : Department of Mines, Minerals and Geology,

Govt. of SikkimDesignation : Senior

Geologist

Perennial subsidence zones along road sections in hilly regions is a challenging job for itsrestorations to site engineers. One of such distress zone along Rangpo-Rorathang road-sectionexisted from more than a decade has been studied using geo physical technique implementation ofOhm’s law (V=IR), where in constant current was supplied through two electrode and resistance ofvarious slopes forming materials was measured at equipotential surface. The low resistivity of thematerials is due to the presence of high water activity and such plane is vulnerable to failure.Therefore, detection of slip surface can be of great interest to site engineers for its permanentmitigation measures. Such studies also plays vital role in long term mitigation measures forrestoration of roads especially in hilly terrain like Sikkim.

Ms Pooja HulajattiImage Delegate ID Theme Details


Research


Organisation : KLS Gogte Institute of TechnologyDesignation : Student

Diseases like Alzheimer’s, Dementia etc. are crippling, degenerative illness that largely affectsthe elderly. These diseases have different side effects such as forgetting the names of friends andfamily, language problems, losing body functionality at different stages.In the presentation, wewould like to propose an idea of a wearable health monitoring and tracking device that wouldundoubtedly help to tackle diseases like these. The wearable device is basically designed keepinghospital scenario in mind and especially for patients with Alzheimer’s, Dementia or similar kindof diseases. The wearable device that will be proposed would be capable of both outdoor using GPSmodule and as well as indoor tracking using RFID technology but with a new approach of movingobjects (that need to be tracked) that switch their position. It can not only track the patient butit is also capable of monitoring the patient’s basic health parameters such as temperature, heartrate, glucose level and blood pressure using best Non-Invasive techniques. It will intimate aboutlocation and health condition of the patient to the caretaker or doctor in case of emergency throughthe SMS gateway. The device will be highly efficient, low cost and responsive rather thaninteractive unlike the existing devices. Feature addition to this could be the shortest distancerecognition to reach the patient in case of medical emergency and many more.

Dr Jaffino GImage Delegate ID Theme Details


Research


Organisation : Aditya College of Engineering ,

SurampalemDesignation : Assistant

Professor

Recent survey says that in India every year more than 1 million peoples were died in road accidents.Accidents are killing more people in India than terrorism or natural disasters. In India when anemergency is reported through 108, the call taker gathers the needed basic information anddispatches appropriate ambulance services to the particular place. When an accident happened innight then no people will report the accident status to emergency call centre. Many people are diedin the accident due to delayed ambulance service and not on time admission in hospitals. Thisproject aims to design a smart automatic accident intimate system based on IOT. The IBM cloud basedservices will be used in this project to share the information using internet If any accidenthappens then the system immediately report the accidents status to the emergency call centre, so theambulance reach the place within minutes and care will be given to the injured people immediately.This system will prevent the death rate during the time of accidents. This Prototype module can beused in automobiles.

Dr Abhijit KarImage Delegate ID Theme Details


Research


Organisation : Jagadis Bose National Science Talent

SearchDesignation : Scientist

Use of light weight multi-functional smart electronic devices/gadget has been observed to be increased faster than its prediction. However, we hardly pay our attention towards the life span (reliability) of all the consumer gadgets; which silently has been found to be decreased drastically in recent times. Critical observations revealed that most of the electronic devices get heated up while in service just after first few months of its use. As a consequence, devices start experiencing malfunctioning or ended up to a pre-mature failure which finally adds up in the E-waste stream; one of the most alarming issue world is facing today. Our present work aims at finding reasons for such premature failures of consumer electronic devices as well as addressing the same in order to improve the reliability of such devices. Any electronic device is manufactured by connecting numerous individual components with the substrate through solder joint / interconnects using lead free solder alloys e.g. Sn3.0Ag0.5Cu (SAC305). Such solder joint interface consists of different intermetallic compounds (IMCs) i.e. Cu3Sn and Cu6Sn5, which ultimately influence the solder joint reliability. Uncontrolled growth of IMCs decreases various mechanical and functional properties like tensile strength, electrical conductivity of the solder joints which eventually affects the device performance. Therefore, the study of structure-property correlation of the IMCs at the interface plays the most vital role in determining the solder joint quality and reliability of the electronic package. A comparative study of solder joint interconnects prepared using multiple layer of Sn thin film (Cu-Sn/SAC/Sn-Cu joint) and without using Sn thin film (Cu-SAC-Cu joint) have been reported. In both the case SAC305 solder paste have been used as filler Microstructural changes have been characterized by Scanning Electron Microscopy (SEM-EDX and XRD. Electrical properties have been investigated by four probe method using SMU 2450. Finally the quality of the solder joint investigated by non-destructive ultrasonic technique It has been observed that electrical resistivity of the interconnect increases with time while the device gets into use. Cu-Sn/SAC/Sn-Cu joint exhibits better electrical conductivity (7.1 * 105 ohm-1 cm -1 in as soldered condition) with superior joint quality compared to the conventional Cu-SAC-Cu joint which exhibits lower electrical conductivity (6.25 * 105 ohm-1 cm -1 in as soldered condition) with inferior joint quality. Evaluation of quality of the solder joint by non-destructive method would help in utilizing the joint component without affecting the physical nature of the joined sample.

Ms MONALISA CHARImage Delegate ID Theme Details


Research


Organisation : National Institute of Technology

DurgapurDesignation : Research

Scholar

Use of light weight multi-functional smart electronic devices/gadget has been observed to be increased faster than its prediction. However, we hardly pay our attention towards the life span (reliability) of all the consumer gadgets; which silently has been found to be decreased drastically in recent times. Critical observations revealed that most of the electronic devices get heated up while in service just after first few months of its use. As a consequence, devices start experiencing malfunctioning or ended up to a pre-mature failure which finally adds up in the E-waste stream; one of the most alarming issue world is facing today. Our present work aims at finding reasons for such premature failures of consumer electronic devices as well as addressing the same in order to improve the reliability of such devices. Any electronic device is manufactured by connecting numerous individual components with the substrate through solder joint / interconnects using lead free solder alloys e.g. Sn3.0Ag0.5Cu (SAC305). Such solder joint interface consists of different intermetallic compounds (IMCs) i.e. Cu3Sn and Cu6Sn5, which ultimately influence the solder joint reliability. Uncontrolled growth of IMCs decreases various mechanical and functional properties like tensile strength, electrical conductivity of the solder joints which eventually affects the device performance. Therefore, the study of structure-property correlation of the IMCs at the interface plays the most vital role in determining the solder joint quality and reliability of the electronic package. A comparative study of solder joint interconnects prepared using multiple layer of Sn thin film (Cu-Sn/SAC/Sn-Cu joint) and without using Sn thin film (Cu-SAC-Cu joint) have been reported. In both the case SAC305 solder paste have been used as filler Microstructural changes have been characterized by Scanning Electron Microscopy (SEM-EDX and XRD. Electrical properties have been investigated by four probe method using SMU 2450. Finally the quality of the solder joint investigated by non-destructive ultrasonic technique It has been observed that electrical resistivity of the interconnect increases with time while the device gets into use. Cu-Sn/SAC/Sn-Cu joint exhibits better electrical conductivity (7.1 * 105 ohm-1 cm-1 in as soldered condition) with superior joint quality compared to the conventional Cu-SAC-Cu joint which exhibits lower electrical conductivity (6.25 * 105 ohm-1 cm-1 in as soldered condition) with inferior joint quality. Evaluation of quality of the solder joint by non-destructive method would help in utilizing the joint component without affecting the physical nature of the joined sample.

Ms SWARNALI NEOGIImage Delegate ID Theme Details


Research


Organisation : JADAVPUR UNIVERSITY

Designation : PROJECT ASSISTANT

The development of a Quartz Crystal Microbalance (QCM) sensor-based portable aroma sensing systemfor Cardamom has been illustrated in this work. When AC voltage is applied, the QCM vibrates inresonant frequency (?f). For sensing applications, QCM sensors are coated with appropriate analytesensitive coating materials such that target VOC, adsorbed on the surface, increases the massresulting in the change in resonant frequency. The sensor is fabricated using Molecular ImprintedPolymer (MIP) which is widely researched in several years because it has excellent selectiveadsorption characteristics. MIP is an imprinting technique used for the preparation of polymers withspecific recognition sites having a predetermined selectivity for a specified template molecule evenat a low interference level due to memory effects. QCM gas sensor is widely used nowadays for thedetection of Volatile Organic compounds (VOC) due to its high sensitivity, linearity, and ease offabrication of VOC specific sensors. The working model of the system comprises of ARM-M4MK20DX256VLH7 microcontroller or data processing from the QCM sensor and the data acquisition iscarried out using a Raspberry Pi 2B. A touchscreen operated GUI has been developed using Pythoncoding language based on the Linux kernel operating system with subsequent data storage andanalysis. Various works have been reported in different peer-reviewed journals based on theextraction of volatiles of different spices in India and abroad [1]. The composition of cardamomessential oil, as studied by different researchers, reveals that 1,8 cineole (20–60%) and?-terpinyl acetate (20–55%), ?-Terpineol are the major chemical components[2,3]. The MIP sensorsare fabricated for ?-terpinyl acetate and ?-Terpineol. The system is designed to take real timedata, and plotting the continuous graph and sensitivity analysis of the sensors. Upon the user’schoice, the measurements are taken for a particular sensor type, when put inside a specific gasenvironment.

Ms DEEPA SACHANImage Delegate ID Theme Details


Research


Organisation : IIT GUWAHATI


Presently, the application of silica-based nanoparticles (SNPs) has gained attention for their highadsorption capability of heavy metal removal from wastewater. Herein, we report the green synthesisof SNPs via a simple chemical method from a new plant source containing silica. Its application as apotential nano-adsorbent for the adsorptive removal of heavy metal ions viz. Pb2+ and Cu2+ wereperformed in synthetic wastewater. The influence of the experimental parameters like adsorbent dose,pH, contact time, temperature, and initial metal ions concentration, was also analyzed. Variousisotherms, kinetics, and thermodynamics models were used to explain the adsorption mechanism. Themaximum adsorption capacity (qmax) of SNPs was achieved 303.03 mg/g and 243.90 mg/g for Pb2+ andCu2+ ions, which fitted well with Freundlich isotherm model and pseudo second-order kinetics

Mr DINESH KUMAR DImage Delegate ID Theme Details


Research

Category : Agricultural Engineering

Organisation : St. JOSEPH'S COLLEGE OF ENGINEERING


Weed control is a critical challenge in the farm operation. Weeds compete with the crop for water, light, nutrients and space, and therefore reduce crop yields and also affect the efficient use of machinery. Mechanical cultivation is commonly practiced in many crops to remove weeds, aerate soil, and improve irrigation efficiency, but this technique cannot selectively remove weeds from the field. The most widely used method for weed control is to use agricultural chemicals (herbicides and fertilizer products) by applying a blanket treatment to a whole field without regard to the spatial variability of the weeds in the field through sprayers. Variability of weed infestation needs to be assessed for site-specific weed management. Since manual weed sampling is too time consuming for practical applications, a system for automatic weed sampling was developed. Information on weed distribution within the field is necessary to implement spatially variable herbicide application. A system that could make use of the spatial distribution information in real-time and apply only the necessary amounts of herbicide to the weed-infested area would be much more efficient and minimize environmental damage. The usage of chemicals and fertilizers can be optimized by a proper weed management system through selectively spraying, spot spraying, or intermittent spraying or precision spraying technologies. Spatial information management systems and precision application systems hold great potential for allowing growers to fine-tune the locations, timings, and rates of herbicide application. The precision herbicide application technologies developed and evaluated use camera to capture the weed spatial distribution patterns. The realization of these technologies could significantly increase farm sustainability and reduce herbicide threats to the environment. So, it is necessary to design and develop a weed management system which may be used for controlling weed in farm field by using digital images.

Dr Kajal SharmaImage Delegate ID Theme Details


Research


Organisation : RIMT university


Kajal Sharma* and Somesh Sharma Rimt University, Mandigobindgarh* Shoolini University, Solan *[email protected] [email protected] Abstarct Wild Himalayan fig (Ficus palmata) is an important medicinal plant (Vern. Phegra, Pheru, Pepri and Fagura). The fruit have strong antioxidant and biological properties that can be used as a possible food additive or in nutraceutical and biopharmaceutical industries. Since the fruit is deficient in calcium and vitamin D, and underexploited hence, development of micronutrient fortified product would certainly provide consumers with healthy products and improve the socio-economic status of the farmers. This study is undertaken to identify and quantify the total mineral contents in ripened fruit and fortified wild Himalayan fig based products by wavelength dispersion X-ray fluorescence technique which is a simple method, recognized as a nondestructive technique to determine the elements from the raw plant material without any chemical treatment and helps to ascertain the nutritional role. The mineral content of calcium (21.0 mg/100g), magnesium (39.1 mg/g), phosphorus (25.7 mg/g), potassium (17.5 mg/g), copper (0.43 mg/g), sodium (535 ppm), manganese (130 ppm), zinc (245 ppm), and silicon (1.0 mg/g) in wild Himalayan fig fruit. This information is very helpful in standardization of products. Among the different concentration tried for fortification of wild fig based jam, squash, RTS-drink and leather, the products fortified with 400 ppm calcium and 600 IU vitamin D2 were adjudged as the best on the basis of sensory analysis. It has been observed that the final concentration of calcium and vitamin D2 was more than 98 percent in all the products and no significant change has been found in the composition of fortified components as a result of processing technique employed. The development of fortified products would help in tackling the malnutrition problems occurring due to the deficiency of calcium and vitamin D2. Keywords: wild, fig, malnutrition, underutilized and calcium.

Mr RAVI PRAKASHImage Delegate ID Theme Details


Research


Organisation : ICAR-NATIONAL DAIRY

RESEARCH INSTITUTE, BANGALORE

Designation : PHD STUDENT

Computational Fluid Dynamics (CFD) simulations of Al2O3–graphite/Propylene Glycol nanofluid basedphase change materials (PCM), engineered for enhancing the heat carrying and storage properties ofmilk chilling fluids, were conducted in Ansys-Fluent 19 in multiphase flow model under transientconditions to study the rapid latent heat exchange behavior of the PCM during fresh raw milkchilling just from the point of harvest. Since, immediate chilling of a perishable commodity likemilk below the safe limit of microbial and physico-chemical deterioration plays crucial role inpreserving quality, shelf-life and safety of not only milk but the milk products derived out of it.In a country like India, where milk production is highest in the world (176.3 MT, NDDB Reports2017-18 [1]), but procurement, collection, chilling, transportation, processing and distributionchain at different stages are rationally linked with unorganized, scattered and small to marginalscale dairy farmers, which ultimately deters the smooth cold chain trek as adept in the developednations. Therefore, in order to tie the stubborn gap between demand and supply of electricity invillages and facilitate ingenuously designed cooling solution for Indian dairy farmers theengineered PCM was encapsulated in a constrained melting stainless steel cooling module and wasintegrated into an ordinary milking pail to facilitate chilling simultaneous to milking even forsingle dairy animal. The thermal properties of PCM measured by KD2-Pro-thermal property analyzer forthermal conductivity and differential scanning calorimeter for specific heats, were found to besuperior as compared to the base fluids used. The CFD studies for 1-5 L of fresh milk chilling byPCM in the cooling module from the drawing temperature (37 °C) to below critical limit (10 °C)took 35-40 min which was more rapid as compared to bulk milk chillers. The experimental qualityoutcomes revealed that the milk rapidly chilled by the cooling system containing engineered PCM wereat par the standards of FSSAI [2] well preserving the physico-chemical characteristics of milk.

Ms kanika SharmaImage Delegate ID Theme Details


Research


Organisation : Shoolini Uviversity Solan HP

Designation : PhD Scholor

Cranberry (Vaccinium macrocarpon) the Native American fruit was in lime light because of its numerous beneficial effects on health. It is a unique, rich source of several classes of bioactive flavonoids including flavanols, anthocyanis and proanthocyanidins which confer it the significant therapeutic potential. In oral diseases like caries and periodontitis, cranberries have shown therapeutic potential owing to their anti-adhesive and other anti-microbial properties. A study was conducted for inhibitory effect of cranberry on Streptococcus mutans which was isolated from dental plaque (biofilm). Biofilms have been implicated in a variety of nosocominial infections associated with medical devices, hospital equipments, and other hard surfaces. These are community of microorganisms that may include fungi, bacteria, yeasts and protozoa attached to a solid surface. Human oral cavity have demonstrated that in the supragingival plaque, S. mutans was the dominant species, with elevated levels of other Streptococci including S. sanguinis, S. mitis, and S. salivarius in addition to lactobacilli and Veillonella. In this study Streptococcus mutans was isolated from different dental plaque samples on blood agar plates which were further identified by Gram’s staining and biochemical test. In gram staining gram positive cocci in chains were observed. Antimicrobial activity of Cranberry was checked against Streptococcus mutans. For that two types of cranberry extracts were prepared and their comparable study was done i.e. Methanolic and Aqueous. The microbiological analysis of the two extracts showed that the Methanolic extract of cranberry showed maximum zone of inhibition i.e 11mm in comparison to aqueous extract (8mm) against Streptococcus mutans. Hence, the study revealed that cranberry can also be one of the alternative that can inhibit the formation of oral Streptococcus mutans which can be beneficial in the inhibition of dental plaque formation and can reverses the co aggregation of oral microorganism. Key words: Cranberry, Dental plaque, Streptococcus mutans, Inhibition.

Mr PRATHAP SImage Delegate ID Theme Details


Research


Organisation : DR MGR EDUCATIONAL AND

RESEARCH INSTITUTEDesignation : Design Engineer

In India, high yield variety of seeds and fertilizers are achieved by increase in productivity of land. But the growth of productivity has been stagnant in recent years, resulting in significant decline in income of farmers. Inadequate to say, the agriculture sector is in a state of distress, which needs enhanced productivity and crop yield in near future. This study aims at enhancing the crop yield by using sensor technology. Sensor based systems will be devised to identify, monitor and calculate the amount of micro, macro nutrients and other relevant physical parameters of soil. Modern technology will be used for choosing the correct crop suitable for the soil and also identifying the proper fertilizers to be used. According to the available nutrients, the information about the type of crop to be grown for specific soil, nature of fertilizers will be updated to the farmers. The measured parameters can be embedded in a device and also be validated with traditional method through Soil testing laboratory and also update the current location of the Field.

References: de Silva, Harsha and Dimuthu Ratnadiwakara (2008), 'Using ICT to reduce transaction costs in agriculture through better communication: A case-study from Sri Lanka', mimeo, 2008

Mr Ankush BariImage Delegate ID Theme Details


Research


Organisation : Pillai College of Engineering


In recent many events related to food and public health has occurred. Many countries established strict rules to ensure the food traceability “Farm to Fork” to meet the demands of customers safety and to ensure public health. This application aims to provide a clear understanding of the food contents, energy and nutritional values, additives, food ingredients that can cause food allergies, and certifications that the product has. to the users by reading the bar codes of food products using the smartphones, querying the data through a food database system created on the Internet. Every registered farmer gets to access information such as best practices, daily market price, weather forecast, warehouse facilities and so on. Such information is sent to their registered account or if the farmer has a smartphone, the same is shared as a notification. It is a portal that connects companies dealing in agriculture inputs, dealers, shops and so on. Registration is based on membership plans. This portal helps farmers to find and connect to the agri-company of their choice, source their input.

Mr ABHIJEET KUMARImage Delegate ID Theme Details


Research


Organisation : G.B.P.U.A&TDesignation : STUDENT

Frio3×3: IoT enabled smart hydroponics set-up Abhijeet Kumar*, Anuj Banola, Yogesh Rawal, Taranjeet Singh B.Sc Student, College of Agriculture, GBPUA&T, Pantnagar, UdhamSingh Nagar, Uttarakhand, India, [email protected]

Abstract: This paper proposes an IoT based smart hydroponics gizmo. We combine cultivation with technology; our set-ups are IoT enabled which enables us to monitor the growth of the crops without any human intervention. This system employs IoT as its key element with sensors (ranging from temperature, light intensity to pH, EC, etcetera) and actuators giving operational convenience. With the advent of such futuristic farming forget about the hassle of managing soil borne diseases; forget watering your plants regularly, consuming chemical free produce and the best part is seeing the journey of this produce from taking baby steps to coming to its final fate; into your plate. This method leverages the superiority of controlled production to give a more guaranteed crop result than soil where mass production is a hit or miss and the plants themselves are subject to the goodwill of the seasons and Mother Nature. This will enable people to monitor the crops at their place using a mobile application and visual appearance and this data feed will be collated and sent to us via IoT hub and cloud. We intend to employ such systems in the urban space and thus create a new generation of farmers, the urban farmers. References: 1. Resh, H. M. Hydroponic Food Production.2013, 13: 978-1-4398-7869-9 2. Waher, P. Learning Internet of Things.2015, 978-1-78355-353-2

Dr karnika prakashImage Delegate ID Theme Details


Research


Organisation : Delhi University

Designation : Faculty

The foremost objective of this work was to evaluate the effect of blending on the oxidativestability index (OSI) and frying stability of cottonseed oil (CSO) when blended with black sesameoil (BSO) and white sesame oil (WSO). Different blending ratios were prepared i.e. 20:80, 40:60,50:50, 60:40 and 80:20 respectively, and there OSI was measured at 110?C, 120?C and 130?Crespectively. CSO, WSO and BSO and their blends in (50:50) ratio were exposed to deep fat frying ofdried pota-to chips at 180 ± 5 ?C for 5 days after 30 min of heating interval. Oil samples andfried potato chips were withdrawn after every frying. The fried oil were evaluated for free fattyacid (FFA), peroxide value (PV) and conjugated diene value (CDV), color, Fourier transform infraredspectroscopy (FTIR) and fatty acid profiling for the CSO, BSO, WSO,WSO: CSO (50:50), BSO:CSO(50:50). Similarly fried potato chips were evaluated for its sensory attributes, moisture loss andfat absorp-tion. In overall, the OSI of CSO was upgraded by the blending, significant improvement inblends was noticed at (psaturat-ed/unsaturated fatty acid ratios of the blends and pure oils throughout the frying daysimplicit satis-fying OSI of BSO:CSO and WSO:CSO. Sensory attributes, moisture loss and fatabsorption as-pects exhibit no significant differences (pBSO and blends BSO:CSO, WSO: CSO) over 5 days of frying.

Dr Gopirajah RajamanickamImage Delegate ID Theme Details


Research


Organisation : Kalasalingam University


Abstract: The structural properties of food plays an important role in the delivery of nutrients through the gastrointestinal (GI) tract. To understand the behavior of food inside the GI tract, an engineered stomach model (ESM) was fabricated and validated based on the information obtained from the magnetic resonance imaging (MRI) of the human stomach. The ESM determines the changes in textural, rheological and disintegration kinetics of chick pea during digestion. The maximum compression force (N) required to breakdown the raw chick peas was higher (350N) than the soaked (100) and cooked (50N) chick pea. The ability to absorb gastric juice was higher in raw chickpea compared to soaked and cooked peas. The change in viscosity of gastric juice is directly affected by the rate of disintegration of the chick pea. The soaked chickpea shows a higher solid loss (55%) with increased digestive fluid viscosity of 1.65 mPa.s as compared with raw chickpea (15% solid loss) having 6mm diameter. The result suggested that the processing significantly (p Keywords: Food structure, digestion model, particle disintegration, and viscosity.

Mr janardhana sri naga sai ganesh medidaImage Delegate ID Theme Details


Research


Organisation : sir c r reddy college of engineeringDesignation : student

As we know about smart grid in electrical engineering i am going to apply the same principle foragriculture by making the different crops monitored at a single place and there will be many thingsthat we need to consider while laying a crop and each type of crop has different types of proceduresand we are embedding artificial intelligence in it in order to make the system work morereliably.The part of A.I is to maintain the water level and updating the data to the server andguiding the agricultural rover to fulfil its purposes like weed removal,seed sowing etc.The completeanalysis of the crop is done by A.I and the recent trends in the agriculture is being proposed tothe users through our customised app.We are also updating the user with the market prices about thecrop.This system does not need any manpower to be involved and we are planning to make it into acomplete one with more benefits.The entire system works from the renewable energy source from hybridenergy collectors and we can make the crop yield rate increased by using this system.We can eventest the type of soil by A.I. and give suggestions for laying suitable crops .By this system we canmonitor the crops lively without going there and do necessary things remotely.

Mr KIRAN KUMAR VImage Delegate ID Theme Details


Research


Organisation : CSIR-4piDesignation : Junior

Research Fellow

Evapotranspiration is defined as the process by which water is transferred from the land to theatmosphere by evaporation from the soil and other surfaces and by transpiration from plants in aspecific area. Evapotranspiration rate from a reference surface is called as the ReferenceEvapotranspiration (ET0). Evapotranspiration is one of the major components of the hydrologic cycleand its accurate estimation is of paramount importance for many studies such as hydrologic waterbalance, irrigation system design and management, crop yield simulation and water resources planningand management. Accurate estimation of ET is important for determining crop water need. The mainobjective of this study is to estimate reference evapotranspiration using best model amongArtificial Neural Network (ANN), Adaptive Neuro-Fuzzy Inference System (ANFIS), Penman-Monteithother Evapotranspiration formulations and Multiple Linear Regression (MLR). The data of maximumtemperature, minimum temperature, relative humidity, wind speed and solar radiation are used as theinput and the reference evapotranspiration is used as the output. For estimation, 70% of data areused for training and 30% of the data are used for testing the models. The performance was evaluatedusing different performance indices viz. Root Mean Square Error (RMSE), Mean Absolute Error (MAE),Mean Absolute Percentage Error (MAPE) and Coefficient of Determination (R2). Estimation of Referenceevapotranspiration by the best method and determine the crop water requirement for major Kharifcereals.

Ms Alka SharmaImage Delegate ID Theme Details


Research


Organisation : ICAR-CIPHETDesignation : Research

Associate

Indian economy is basically agrarian economy. A shift from agriculture to agribusiness has a large potential to contribute to the national income while at the same time providing direct employment and income to the numerically larger and vulnerable section of the society.Agripreneurship is not only an opportunity but also a necessity for improving the production andprofitability in agriculture and allied sector. The Indian food industry is poised for huge growth,increasing its contribution to world food trade every year due to its immense potential for valueaddition, particularly within the agri food processing industry. Traditionally IPR was not appliedto agriculture. In recent times this position has changed and increasinglyagro-processing/agribusiness created lot of opportunities leading to more elaborated research anddevelopment. Types of intellectual property relevant to the agribusiness include patents, plantvarieties, trade marks, copyright, trade secrets and design rights. It covers everything from theplant varieties, production of ingredients and creation of recipes to the labelling, marketing andbranding of the finished product. Every food sector business from start up to multinational createsintellectual property. These assets can be extremely valuable, particularly when a company becomessuccessful. If any form of intellectual property is not protected at the beginning, its value canbe lost, stolen or diminished. The optimal IPR use ultimately depends on the particular technologyand the market it is intended for. Conclusively, Intellectual property rights (IPR) can support thegrowth of an economy and society by encouraging the development of new agroprocessing technologiesand can generate more opportunities for farmers/entrepreneurs/agripreneurs for establishing theiragro-processing units

Dr K SrinivasanImage Delegate ID Theme Details


Research


Organisation : Sri Ramakrishna Engineering

CollegeDesignation : Professor and

Head

The biggest problem prevailing is the disposal of food and agro wastes including the expired foodsand converting the waste into useful energy. Overpopulation has resulted in exploitation of naturalresources on a large scale. The demand for an efficient energy source has led to production ofelectrical energy through various natural sources. Yet, this production has also induced theenvironmental pollution through by-products released into the environment after generation process.Clean energy generation using biogas plants helps us to generate constant electricity and also helpsto manage the agro, food and animal wastes being introduced into the environment. The idea proposedaims to generate, control and monitor the process of clean energy production using food andagricultural waste materials. While the existing biogas plant helps in the generation of gas forfuelling the combustion process, the proposed method focuses in generating clean energy in the formof uninterrupted electricity from the food, plant and animal wastes. To overcome inefficiency anddelay in the digestion of wastes, a detailed study on the time taken for fermentation for each inputfeed is done and the time value for each material to make the drum rise to maximum is calculated.Thus, a range of food wastes like expired packaged foods have been identified as an effective inputfor bio-gas generation along with traditional animal wastes. Furthermore, a monitoring system thatchecks on the quality and quantity of the reactor contents is included. It comprises of sensingdevices such as load cell for weighing the tank-fill and pH sensor for checking the acid-base levelinside the tank. In addition to this, the flow rate of gas given to the biogas generator ismonitored from time to time. The abnormality in pH and quality of gas generated are corrected usinga stirrer mechanism fitted with the drum. Using a remote sensing Internet of Things (IoT) alertsystem, the above additions are used to bring abnormality in level/value of the biogas system andamount of inlet feed to the operator’s attention. The valve opening is then controlled, therebyapproximating the amount of energy generated.

Ms SUSHMA TAMTAImage Delegate ID Theme Details


Research


Organisation : G.B.P.U.A&T PANTNAGAR

Designation : Ph DResearch Scholar

Soil erosion and water loss is a severe environmental issue throughout the world. For conservingsoil and water, grasses are very effective conservation measures. Plant roots are more efficient incontrolling rill and gully erosion rates while plant cover is more efficient in controlling splashdetachment and inter rill erosion rates. The aim of this study was to evaluate the impact of grasscharacteristics i.e. plant root and shoot characteristics in controlling soil erosion and runoff.The experiments were conducted at the Hydrologic Simulation Laboratory available in the departmentof SWCE at G. B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand. The soilused is silt loam, having pH 7.34, EC 65.04 µs, organic matter 1.858 and bulk density is 1.32g/cm3, which is very efficient for plant growth. In this study, hydraulic flume (10 m*1.2 m) wasused as an experimental plot in which Perennial Napier grass (Pennisetum purpureum) was grown andrainfall simulator was used to perform the experiment. The experiment plot was put under fourrainfall intensities and three slopes to observe the effect of Napier grass characteristics onrunoff and sediment yield. In this study, three treatments were used (i) bare plot (no crop plot),(ii) plant plot and (iii) root plot i.e. clipping the part of the shoots just before the experiment.The runoff and sediment yield samples have been collected at different stages (90, 120 and 150 days)of plants with shoot and without shoot under varying hydrologic and land slope conditions. Theresults indicate that an increase in root cover as well as increase in shoots cover, decrease soilerosion rates. The shoot portion usually contributed more to the runoff reduction than the rootportion. The results of this study can be used to specify the effect of vegetation characteristicson soil erosion. Furthermore, we found which portion of vegetation control measures are moreeffective to control soil and water losses using Napier grass.

Dr Manoj K PatelImage Delegate ID Theme Details


Research


Organisation : CSIR-Central Scientific Instruments

OrganisationDesignation : Senior

Scientist

Electrostatic force field has been exploited in the design and development of a handheldair-assisted electrostatic sprayer for agrochemicals spraying. Electrostatic spraying is a novelapproach for agricultural applications to increase the mass transfer efficiency, pesticidebio-efficacy, uniform deposition, maximum canopy coverage and liquid pest to reach the hidden areasand underside of the target by reducing the drift of active ingredients of agrochemicals from thetarget. Electrostatic spraying is one of the most efficient and effective methods to apply theprotective liquid based agrochemical sprays to crops and orchards to protect from many dreadfuldiseases and insects. It offers a very favorable approach to increase agrochemicals dropletdeposition onto the surface of crops and orchards with two-fold of mass-transfer efficiency ofactive ingredients. In this paper, a hand-held air-assisted electrostatic sprayer has been designedand developed for agricultural applications and the study was carried out to evaluate theperformance of indigenously developed air-assisted electrostatic sprayer. The effects of the designparameters such as applied high voltage, charge-to-mass ratio, load current, conductivity range,applied air pressure and liquid flow rate. Different spray performance parameters i.e. number mediandiameter (NMD), volume median diameter (VMD), uniformity coefficient (UC), droplet density (DD),volume of spray deposition (SD) and area covered (AC) by droplets were determined with the help ofwater sensitive paper (WSP) method of deposition collection. The values of number median diameterand volume median diameter for indigenous electrostatic sprayer were 66.05 to 143.75 µm and 79.20to 130.23 µm which were significantly lesser as compare to knapsack sprayer 98.48 µm to 145.85 and194.68 to 381.27 µm). There is comparatively lesser variation in uniformity coefficient forindigenous electrostatic sprayer 1.66 to 2.08 than knapsack sprayer 1.78 to 2.94 at 5% level ofsignificance. The droplet density for indigenous electrostatic sprayer was significantly more ascompared to knapsack sprayer. The area covered by droplets also found significantly higher forindigenous electrostatic sprayer than the knapsack sprayer. An excellent change-to-mass level ofapproximately 6.9 mC/kg has been found at applied voltage of 1.5 kV, air pressure 3 bar and liquidflow of rate of 190 ml/min to achieve the wraparound effect of charged droplets.

Mr Daniel Prakash KushwahaImage Delegate ID Theme Details


Research


Organisation : Govind Ballabh Pant University of

Agriculture and Technology, Pantnagar

Designation : Ph. D. Scholar

In recent years, many methods and soil amendments have been used to increase vegetation growth andsubsequently to cease soil movement on steep slopes of Uttarakhand hills. In this study, soilamendments viz. biochar, polyacrylamide and gypsum have been used to impose six different treatmentsviz. control (C), gypsum (G), biochar (B), gypsum with polyacrylamide (G+PAM), biochar withpolyacrylamide (B+PAM) and biochar with gypsum (B+G). Square plots of 9 sq. m. have been preparedover moderate slop of 11.71 % for treatments. Each treatment has been replicated three times overrandomized block experimental design. Grinded rice husk based biochar have been applied at twodifferent depths viz. 20 cm depth and 2.5 cm @ 400 gm per sq. m. in each depth, about one monthprior to experiment. Liquid polyacrylamide (0.50 % solution) and powdery gypsum have been applied, @2 and 250 g per sq. m., respectively, over surface of bare soil just before experiment in thepresence of 28.21% moisture content. Field has been left for almost two months, so that naturalgrasses could achieve upto some height in feet. Above and below ground biomass have been measuredfor each experimental plot to compare the results. Results indicate that B+PAM treatment is betterthan other treatments to increase vegetation growth. Result from best to inferior is found as B+PAM> B+G > G+PAM > C > G > B. Biochar increases the pore spaces of soil which causes more infiltrationand less runoff whereas PAM and gypsum helps soil to be stable soon. Notwithstanding, Biochar basedplots have increased soil erosion because of initial ploughing and loosening of top soil. Gypsumhelps to reduce soil erosion but not useful for vegetation growth. Furthermore, we obtained thatbiochar requires some more period of establishment in soil to increase vegetation and to reduce soilerosion.

Ms Annu RaniImage Delegate ID Theme Details


Research


Organisation : G.B.P.U.A& T Pantnagar

Designation : Ph D research scholar

Wear is known to be as the reduction of material under excess of resources conditions and isconsidered as one of the crucial issue of the material used in Agriculture engineering. Varioustypes of wear have been considered such as abrasive, erosive, corrosion, oxidation etc. Abrasivewear is the most notable source of mechanical damage of equipment and tools forthcoming in contactwith abrasive anatomy. For reduction of wear problem various methods have also been evolved in thesame manner with coating and heat treatment of components which are pick on the basis of variousconditions under which the component has to perform the desired work. The wear of the componentbuild upon its surface properties like roughness, microstructure and hardness. The high wear rate ofground engaging tools led to huge loss of material, recurring labor, downtime and replacement costsof worn out parts. Hard facing is commonly employed method to improve surface properties of tillagetools. equipment, ground engaging tool. Wear is the main reason for the loss of enforcement of thetools for agricultural machinery. Most of agricultural disc are manufactured locally which arehardly as per with the standards which affects operational life of tillage tool. So, there is aessential to study wear characteristics of agricultural disc. This work aims to highlight confinelaboratory in circular soil bin and field tests to determine weight, diameter and thicknessreduction wear loss of agricultural. The effect of different factors on the wear of agriculturaldisc is determined. And generate the mathematical relationships are developed to estimate the wearlife of the agricultural disc on the basis of laboratory test and field test. Regression models aredeveloped to estimate the working life of the agricultural disc.

Mr Nitish SahuImage Delegate ID Theme Details


Research


Organisation : Amity university chhattisgarhDesignation : Student

Our country's main occupation is agriculture. Around 6070%% of Indian population directly or indirectlydepends upon agriculture sector and currently it contributes to 1617% of the GDP. After green revolution, the growth of crops has been increased, but simultaneously the use of pesticides and insecticides has drastically increased, which resulted in soil erosion, production of hazardous crops, contamination of surface and groundwater source of drinking water with nitrates and pesticides and many more. Instead of directly spraying the insecticides and pesticide my innovative device deals with insects and pests using light source. As we know that insects and pests attracts towards the light of wavelength 300-420 nm which includes UV light. This device attracts most of the insects and pests which causes damage to crops using light source of the above mentioned wavelength.There is a sprinkler in topwhich sprays homogenised insecticides and pesticides in a appropriate time interval. Also there is storage unit for dead insects and pest because dead bodies of insects and pests can be used as fertilizers after few steps of processing. As Insects and pests are rich in nitrogen(urea, ammonium ), and various organic compounds. And as the device is controlled by light sensor, so the user does not need to switch on and off the device manually. And also the device uses solar panels and a rechargeable battery as well. Object of this device is to provide an inexpensive trap which attracts, entraps and allows for easy disposal of insects and pests. Also to provide natural and almost free of cost fertilizer using solar energy as a power source. This device also promotes organic farming.

Mr Parthiban PImage Delegate ID Theme Details


Research


Organisation : U.R Rao Satellite Centre (ISRO)Designation : Scientist

This paper discusses a novel methodology to design satellite constellation for various revisitperiods with the minimum number of satellites. The procedure is to extract single satellite’sascending or descending node points for the given revisit period. Then the distance between the nodepoints are covered by placing the satellites in orbit with exact phasing angles derived based onaltitude and roll tilt capacity of the satellite. An algorithm has been designed using thismethodology, to extensively analyze the number of satellites required for revisit periods rangingfrom 1 hour to 24 hours. The proposed method ensures the minimum number of satellites are requiredfor a given revisit period. In addition, this paper conducts sensitive analysis and parametric studyto obtain the number of satellites required with respect to altitude, roll bias and bore sightangle. The results indicated, if the revisit period is dictated in terms of the orbital period (n ×orbital period; n > 0) then the minimum number of satellites required is significantly reduced.

Ms Ketha reddy RangannagariImage Delegate ID Theme Details


Research


Organisation : BVRIT HYDERABAD college of engineering for womenDesignation : Student

Satellites in orbit around Earth are used in many areas and disciplines, including space science, Earth observation, meteorology, climate research, telecommunication, navigation and human space exploration. They offer a unique resource for collecting scientific data, commercial opportunities and various essential applications and services, which lead to unrivaled possibilities for research and exploitation. In almost 60 years of space activities, more than 5250 launches have resulted in some 42 000 tracked objects in orbit, of which about 23 000 remain in space and are regularly tracked by the US Space Surveillance Network and maintained in their catalogue, which covers objects larger than about 5–10 cm in low-Earth orbit (LEO) and 30 cm to 1 m at geostationary (GEO) altitudes. Only a small fraction – about 1200 – is intact, operational satellites today. This large amount of space hardware has a about 24% of the cataloged objects are satellites (less than a third of which are operational), and about 18% are spent upper stages and mission-related objects such as launch adapters and lens covers. More than 290 in-orbit fragmentation events have been recorded since 1961. Only a few were collisions. The majority of the events were explosions of spacecraft and upper stages. As a consequence of the rising debris object count, the probability for catastrophic collisions will also grow progressively? doubling the number of objects will increase the collision risk by approximately four times. The main cause of orbit explosions is related to residual fuel that remains in tanks or fuel lines, or other remaining energy sources, that remain on board once a rocket stage or satellite has been discarded. As a consequence of the rising debris object count, the probability for catastrophic collisions will also grow progressively. Doubling the number of objects will increase the collision risk by approximately four times.

Mr Pankaj AgarwalImage Delegate ID Theme Details


Research


Organisation : Indian Space Research Organisation

Designation : Sci/Eng 'SF'

The effect of gravity release in orbit poses severe challenges in meeting surface profile requirements of large reflectors with spacecraft. Usually, CFRP sandwich (solid) construction is used as preferred option for antenna reflectors of communication spacecrafts due to obvious advantages like high specific stiffness & better stability in orbit. With the increasing size of antenna reflectors the issues related to deformation due to gravity release become more severe. The deployable antenna reflector is supported in various support conditions & orientations during realisation & testing under gravity. These different support conditions & orientations cause deformation of antenna surface profile in different ways which may lead to loss in antenna performance. In order to mitigate the effect of 1g, an analytical estimate is carried out and based on this RF performance is evaluated with appropriate compensation. Also near zero ‘g’ condition will be simulated during testing of hardware. In this paper, the design of antenna reflector and the effects of gravity on antenna reflector with different support conditions & orientations are analytically studied. Also, the analytical results are experimentally established.

Mr DIBYENDU SURImage Delegate ID Theme Details


Research


Organisation : Narula Institute of Technology


An effort is given in this paper in order to correlate the latitudinal extent of Disturbed DynamoElectric Field (DDEF) with the geomagnetic storm intensity in the northern hemisphere. VerticalTotal Electron Content (VTEC) data at different International GNSS Stations (IGS) at the samegeomagnetic longitude has been used during the Halloween solar storm (duration of observation:October 26 – November 1, 2003). VTEC observed from Russian, South Korean and Pacific oceanlongitudes are used in this purpose. Three back to back Coronal Mass Ejection (CME) geomagneticstorms were observed during the duration of observation. The first CME storm was observed on October27 (minimum DST= -52nT at 5UT). Due to Prompt Penetration Electric Field (PPEF), VTEC increases atthe main phases. On October 28 the VTEC at Russian chain decreases but this effect was absent inSouth Korean latitudes and subsequent southern latitudes. In response of the intense storms onOctober 29 and October 31 (minimum DST= -350nT) the latitudinal extent of DDEF reaches towards thePacific ocean latitudes. These observation suggests positive correlation of the latitudinal extentof DDEF with the intensity of geomagnetic storm. It should also be noted that the thermosphericplasma transport process may also contribute towards the decrease in VTEC in the low latitudes.

Ms TRISHA PAULImage Delegate ID Theme Details


Research


Organisation : Narula Institute of TechnologyDesignation : Student

In this paper, we shall discuss the effects of an intense geomagnetic storm in the Indian longitudesector. Data from the International GNSS Service or IGS station Lucknow (18.08°N, 155.58°Egeomagnetic and 26.85°N, 80.95°E geographic) is used for this study. Lucknow is situated at regionbeyond the northern crest of Equatorial Ionization Anomaly (EIA). We have observed an intensegeomagnetic storm (Dst ? - 100 nT) during 24th August to 31st August, 2018. We have also analyzedthat the Initial Coronal Mass Ejection or CME storm starts during 12 UT on 25th August, 2018. Thebeginning of the main phase of CME storm is observed during 14 UT on 25th August, 2018.the mainphase continued till 7-8 UT on 26th August, 2018 (minimum Dst = -174 nT) . Because of the PromptPenetration Electric Field or PPEF, TEC enhancement has been observed during 10 UT on 26th August,2018. On 28th August, 2018 another geomagnetic storm has been observed due to Coronal InteractionRegion (CIR) has been observed. In response of that storm, TEC increment of 5.57 TECU was observedon 28th August, 2018.

Ms Pavithra sulladImage Delegate ID Theme Details


Research


Organisation : KLS gogte institute of technology

belgaum,karnatakaDesignation : student

SPACE DEBRIS Pavithra sullad* Email id : [email protected] KLS gogte institute of technology,belgavi,Karnataka. ABSTRACT Space exploration by humans has littered the cosmos with satellites, spent rocket stages and collisions which lead to massive problems in space. The size of debris ranges from less than 1cm to a complete satellite. To solve this problem there are few techniques discovered by some space faring nations, considering altitudes, speeds and orbit perturbations of debris. Here, in this research proposal robot assisted technique is focused. A cube satellite traveling at required speed carries robots will target particular junk and shoot robots on them, the robot will act accordingly such that either the debris is forced to re-enter atmosphere and burn which is for lower earth orbit junk or de-orbited and pushed away from gravitational force in case of geostationary orbit. Keywords :- cosmos, robots, cube satellite and orbit. References: H klinkrad: brief of space.

Dr Arjun DeyImage Delegate ID Theme Details


Research


Organisation : ISRODesignation : Scientist

Vanadium Oxide Based Thin Films with Reversible Phase Transition for Smart Radiator Application of Spacecraft Thermal Control Arjun Dey*, Sangram Keshari Sahoo, Mohammed Adnan Hasan, N. Sridhara** and A. Rajendra Thermal Systems Group, U. R. Rao Satellite Centre, Indian Space Research Organisation, Old Airport Road, Bengaluru-560017 *[email protected], [email protected]

Abstract: The miniaturization and sophistication of spacecraft (micro- and nano-satellites and human space programs), demands significant mass reduction and consequently smarter way of thermal control by means of automated passive way. Conventionally, less reliable active elements such as heater and bulky coolers are used to control the radiative heat transfer for the satellites. Therefore, an automated way of control the radiative heat transfer by light weight, reliable, smart passive element should be devised. Vanadium oxide based (VO2 and V2O5) [1,2] films shows reversible phase transition at critical temperatures. This phase transition is thereby resulting in change of its functional properties. Upon transition, such tuneable/variable emittance coatings can significantly alter the IR emissivity of the outer surface of satellites with changes in temperature, thus allowing efficiently passive thermal control. In the present work, vanadium oxide composite (e.g., vanadium oxide-molybdenum oxide [3,4] and vanadium oxide-titanium oxide) thin films are developed by RF magnetron sputtering with varying RF powers which would show the smart transition around 45 to 50 °C evaluated by DSC. The present transition temperature is much lower as compared literature reports which an important mandate and challengeable specification for spacecraft application. Further, through microstructural (e.g., XRD, FESEM, EDS, XPS), thermo-optical and temperature based electrical characterisations were carried out. References: 1. Porwal, D. et al., RSC. Adv. 2015, 5, 35737-35745. 2. Palai, D., et al., Phil. Mag. Lett. 2016, 96, 440–446. 3. Dey, A. et al., Sci. Rep. 2016, 6, 36811. 4. Esther, A. C.M. et al., Infrared Phys. Technol. 2017, 85, 273–279.

Mr Rahul SunilImage Delegate ID Theme Details


Research


Organisation : SRM Institute of Science and Technology

Designation : Recently Graduated Student

There has been a lot of advancements in the field of rocket propulsion since the first rocketlaunch. Liquid propellants are used in the upper stages of the rocket since the thrust produced canbe varied which is one of the main advantages of using rocket propellant in the upper stages.Further, it is also used as maneuvering thrusters. One of the disadvantages of liquid propellant isthe comparatively low thrust produced by it compared to solid propellant. In this project, we aim toincrease the propulsive characteristic of a liquid propellant which is already pre-determined, N2O4and MMH (Monomethyl Hydrazine), by adding highly energetic materials into the propellant. We shallbe conducting the simulations based on ordered hybridization and distinct hybridization. We shall beusing the NASA CEA (Chemical Equilibrium with Applications) Software to carry out the simulations.The input parameters which we will be varying are the temperature, chamber pressure, O/F ratio,nozzle area ratio. The key parameters we will be observing Is the Specific Impulse, CharacteristicVelocity. Liquid propellant has multiple applications, from upper stage rockets to orbitalsub-orbital thrusters as well as maneuvering thrusters. It can also be used for interplanetarytravel as well as to take off with heavy load instruments. Our aim is to reduce the dependence oncryogenic propellants and start relying on more normal propellants. This can be achieved byimproving the efficiency of the base liquid propellant by adding additional materials and byextension of this task to provide a propellant for a wide variety of applications.

Ms SHREYA BARADImage Delegate ID Theme Details


Research


Organisation : SRM UNIVERSITY, Chennai KTR

Designation : student

It has been a long time since intellects have started noticing and acquired data on how much affect and danger , the existence of space debris could cause to space programmes and near-earth space activities. Even a minute debris segment of 1-10 mm could damage a system of upto 10 cm impact at least. Aiming to minimize and capturing space debris by development of multiple equipped system having capability of capturing various sizes of debris and hence being economical and more profitable. This paper presents the design and analysis of the concept of multiple concentric web structure converged , altogether connected to nodes at the end. it has specific features of capturing different web sized debris depending on the loading and sustainable capacity. The Absolute Nodal coordinate formulation (ANCF) model is used to validate , authorize the significant application and compute the ability of the system. The design is made with CATIA v5 software tool and synthesized in MATLAB. This technology will be able to capture those debris with range greater than or equal to the minimum net size and the maximum net size. The nodes of Multiple web will direct and orient system selected coordinates leading the web full of active debris to the graveyard orbit.

Mr Vedant KediaImage Delegate ID Theme Details


Research


Organisation : Birla Institute of Technology Mesra Patna

CampusDesignation : Student

Abstract Space research is one of the leading fields in the present scenario. We need to explore this field to deal with various objectives such as communication, defence, life in different field, environment, various celestial bodies, black hole etc. Propellant used by the space vehicle is one of the key elements in this field. Propellant is the fuel used to overcome not only gravitational force but also help in accelerating against the gravity to reach the space. It is also used to produce thrust, projectile motion to a space vehicle etc. Temperature and unconditional burning are the two basic parameters of the propellant. Functionality of the propellant depends on specific thrust, regression rate, specific impulse, structural property, thermodynamic properties, weight, boundary velocity diagram etc. Different types of propellant are used such as solid, liquid, mixed phase, green propellant etc. Here we present a systematic study on this different type of propellant keeping good physical property, light weight, low cost and environment friendly. So that we can predict best fuel for future rocket engine by keeping environmental safety ,low cost and high performance as the basic parameter. . Key words: Propellant; thrust; thermal capacity Rocket

Mr N. SridharaImage Delegate ID Theme Details


Research


Organisation : Indian Space Research OrganisationDesignation : Scientist

Vanadium Oxide Based Thin Films with Reversible Phase Transition for Smart Radiator Application of Spacecraft Thermal Control Arjun Dey*, Sangram Keshari Sahoo, Mohammed Adnan Hasan, N. Sridhara** and A. Rajendra Thermal Systems Group, U. R. Rao Satellite Centre, Indian Space Research Organisation, Old Airport Road, Bengaluru-560017 *[email protected], [email protected] **[email protected], [email protected] Arjun Dey OR N. Sridhara will present Abstract: The miniaturization and sophistication of spacecraft (micro- and nano-satellites and human space programs), demands significant mass reduction and consequently smarter way of thermal control by means of automated passive way. Conventionally, less reliable active elements such as heater and bulky coolers are used to control the radiative heat transfer for the satellites. Therefore, an automated way of control the radiative heat transfer by light weight, reliable, smart passive element should be devised. Vanadium oxide based (VO2 and V2O5) [1,2] films shows reversible phase transition at critical temperatures. This phase transition is thereby resulting in change of its functional properties. Upon transition, such tuneable/variable emittance coatings can significantly alter the IR emissivity of the outer surface of satellites with changes in temperature, thus allowing efficiently passive thermal control. In the present work, vanadium oxide composite (e.g., vanadium oxide-molybdenum oxide [3,4] and vanadium oxide-titanium oxide) thin films are developed by RF magnetron sputtering with varying RF powers which would show the smart transition around 45 to 50 °C evaluated by DSC. The present transition temperature is much lower as compared literature reports which an important mandate and challengeable specification for spacecraft application. Further, through microstructural (e.g., XRD, FESEM, EDS, XPS), thermo-optical and temperature based electrical characterisations were carried out. References: 1. Porwal, D. et al., RSC. Adv. 2015, 5, 35737-35745. 2. Palai, D., et al., Phil. Mag. Lett. 2016, 96, 440–446. 3. Dey, A. et al., Sci. Rep. 2016, 6, 36811. 4. Esther, A. C.M. et al., Infrared Phys. Technol. 2017, 85, 273–279.

Ms K.MAUNA SREEImage Delegate ID Theme Details


Research


Organisation : coimbatore institute of technologyDesignation : student

An intelligent Pico satellite system for tracking and monitoring system can provide extremelyaccurate location information for some specific place like military base camp, soldiers or relatedpeople who are very important to surveillance in sensitive times. This information is used to findprecise location of these places and can be used automatically for contact with defence enforcementofficials, The Global Positioning System (GPS) Satellite, several local relay station, CentralMonitoring Station (CMS), Portable Remote Tracking Device (PRTD), tracking satellite system aremajor components of the approach. The GPS generates a position signal and the signal is transmittedto the PRTD when surveillance of the military base camp. It enables a CubeSat to exchangeinformation with ground stations and/or other CubeSat in orbit. The paper has presented newapproaches to design and implementation of all the sub systems for small satellites that increasethe level of autonomy. Systems will continuous monitoring the army base camp to make higherprotection from the terrorist attack like (URI base camp)

Ms Sindhuja .Image Delegate ID Theme Details


Research


Organisation : R.V COLLEGE OF ENGINEERING

BANGALOREDesignation : Student

Nanosatellites are proven to provide economic access to space and multitudinous efforts are undertaken to realize sophisticated missions in them, particularly by academicians and students. Built by Team Antariksh – the student space technology team of RV College of Engineering (RVCE), RVSAT-1 is a 2U Cubesat which houses a microbiological experiment as payload. It has very narrow operating temperature range and is sensitive to temperature fluctuations. Calculation of orbital thermal loads on a nanosatellite is crucial for its success and calculation of orbital thermal loads of RVSAT-1 is studied in this paper. RVSAT-1 is a spacecraft intended to be placed in a polar sun synchronous Low Earth Orbit. It experiences solar, albedo and earth IR as external thermal loads and these are functions of its orbital parameters. Regression and beta angle of the orbital plane is computed for all days of its mission. External thermal loads are minimum in the eclipse region and the eclipse region is dependent on the orientation of the orbital plane with respect to sun. The angular locations at which it enters and exits the eclipse region are determined. With the information of eclipse region for all the computed beta angles, thermal loads at various angular positions are determined. Considering the solar activity and the elliptical nature of earth’s orbit around the sun, six set of heat fluxes, three for hot case and three for cold case are computed at each point. Thermal flux at every location of the nanosatellite mission is obtained. A detailed analysis of the obtained heat flux data lead to forecasting the worst hot and cold case thermal loads that RVSAT-1 would experience during its mission.

Dr Priyank KumarImage Delegate ID Theme Details


Research


Organisation : Birla Institute of Technology, Mesra, Ranchi


Cavities are generally defined as the discontinuities or cut out in geometries, they are inherent structures. Wheel bays, bombing bays of aircrafts, windows in automobiles, propeller hubs of naval ships are some of the example of the cavities. Study of flow physics and characterization of flow features calls for an increased research attention towards this field. Currently researches are conducted to control the noise generation from cavity using active and passive methods. Previous studies conducted in this field shows that flow features inside the cavity are dependent on upstream flow conditions like Reynolds number (Re), boundary layer thickness(?), Mach number (M), and cavity dimensions (L, D, W). The L/D ratio of cavity is most widely used parameter for classifying cavity types, they are classified as (a) deep cavities (L/D 1). Shallow cavities are further divided into three categories: open cavities (1 13). Deep cavities resonate in depth wise mode while closed cavities are not associated with any type of acoustic tones, however open cavity flow physics is governed by Rossiter’s feedback loop mechanism: breakage of shear layer, vortex shedding, vortex collision and acoustic wave formation. Studies have also showed that vortex shedding takes place in both cases of laminar and turbulent boundary layer with only difference being that in the case of laminar boundary layer vortex shedding is quasi periodicand intensity of oscillations in case of turbulent flow are less severe than that of laminar case. Most of the studies conducted on cavity flow are at higher Mach numbers or assume cavity to be 2D cut-out or axis symmetric in nature. However, every geometry cannot be treated as 2D or axis-symmetric. Thus, the present study aims to deal with cavity as a 3D geometry and elaborate on flow physics inside the cavity. The experimental studies using water tank visualization (Fig. 1) show that disturbance in flow is induced due to breaking of shear layer along the length of cavity leading to vortex shedding. It is also observed that the flow physics turns out to be three dimensional if the cavity span is increased. To the best of our knowledge, such studies are limited nationally as well as internationally.

Mr Surendra KUMARImage Delegate ID Theme Details


Research


Organisation : AcSIR-AMPRI Bhopal

Designation : PhD (SRF-NET)

Electromagnetic pulse technology is a high energy rate forming (HERF)/high velocity rate formingprocess which is used in various sectors such as aerospace, automotive, nuclear, medical etc. [1].Electromagnetic pulse forming process depends on various parameters, such as velocity,electromagnetic force, voltages, magnetic field, design of coil and samples, frequency, currentdensity, stand-off distance etc. After the deformation of parts various advantages are mitigatedlike spring-back and wrinkling effect, enhanced the formability of the parts etc. [1]. In thistechnique, joining of similar or dissimilar materials without using any types of filler/othersmaterials and heat affected zone is also negligible in this technique. Therefore, mechanicalproperties are better than the others unjointed placed. In the present study, literature review theeffect of various parameters such as magnetic force, velocity, voltages, magnetic field, design ofcoil and samples, frequency, current density, stand-off distance on the deformation behaviour oftubes by electromagnetic forming process [2].

Mr Alok Kumar ChaudharyImage Delegate ID Theme Details


Research


Organisation : University College of Engineering and Technology, Vinoba Bhave

University, Hazaribag, Jharkhand


Piezoelectricity a new source of electricity for Railway

Alok Kumar Chaudhary University College of Engineering and Technology, VBU, Hazaribag Contact Author’s e-mail address: [email protected]

Abstract This is time to develop that type of energy which is clean and green. Indian railway is using its large amount of electricity from fossil fuel type initial source. At this time Piezoelectricity can be very good enough source of energy for the requirement of railway because during electricity generation and using no pollution is here. There are various place on railway station are available where large pressure applied due to its application. That places can be use as electricity generation using piezoelectric transducer. For it piezoelectric transducer fitted at different place of railway station. Main output can be get by using this transducer in the railways track which get much pressure and can give large amount of electricity and this electricity can fulfill large amount of electricity need of railway. For calculation of force on track ANSYS like software have used.

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