IFMBE Proceedings

Volume 60

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James Goh

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The International Federation for Medical and Biological Engineering, IFMBE, is a federation of national and transnationalorganizations representing internationally the interests of medical and biological engineering and sciences. The IFMBE is anon-profit organization fostering the creation, dissemination and application of medical and biological engineering knowledgeand the management of technology for improved health and quality of life. Its activities include participation in the formulationof public policy and the dissemination of information through publications and forums. Within the field of medical, clinical,and biological engineering, IFMBE’s aims are to encourage research and the application of knowledge, and to disseminateinformation and promote collaboration. The objectives of the IFMBE are scientific, technological, literary, and educational.

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Isnardo Torres • John BustamanteDaniel A. Sierra (Eds.)

VII Latin American Congress onBiomedical Engineering CLAIB 2016,Bucaramanga, Santander, Colombia,October 26th – 28th, 2016

123

EditorsIsnardo TorresPresidenteAsociación Colombiana de Bioingeniería

y Electrónica Médica - ABIOINBucaramangaColombia

John BustamanteCentro de BioingenieríaUniversidad Pontificia Bolivariana - UPBMedellínColombia

Daniel A. SierraEscuela de Ing. Eléctrica, ElectrónicaUniversidad Industrial de SantanderBucaramangaColombia

ISSN 1680-0737 ISSN 1433-9277 (electronic)IFMBE ProceedingsISBN 978-981-10-4085-6 ISBN 978-981-10-4086-3 (eBook)DOI 10.1007/978-981-10-4086-3

Library of Congress Control Number: 2017934456

© Springer Nature Singapore Pte Ltd. 2017, corrected publication 2018This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights oftranslation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or informationstorage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specificstatement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date ofpublication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for anyerrors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.The IFMBE Proceedings is an Of fi cial Publication of the International Federation for Medical and Biological Engineering (IFMBE)

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Preface

The CLAIB 2016 Organizing Committee, representing the Regional Council of Biomedical Engineering for Latin America(CORAL) with the Latin American and international scientific community has carried out the VII Latin American Congress onBiomedical Engineering (CLAIB2016) www.abioin.com/infoclaib2016.html. This event, which has taken place since 1998,had its seventh edition in Bucaramanga, Santander, Colombia, at Universidad Autónoma de Bucaramanga (UNAB).

The organization of the Latin American Congress on Biomedical Engineering was carried out by the “AsociaciónColombiana de Bioingeniería y Electrónica Médica- ABIOIN”. This congress was also supported by academic teams fromUniversidad Industrial de Santander, Universidad Pontificia Bolivariana, Universidad EIA, Instituto Tecnológico Metropoli-tano de Medellín, Universidad Javeriana and the Universidad Autónoma de Bucaramanga as the host University. Also, fromthe medical field, the FOSCAL, International Hospital of Colombia, FCV, among other organizations and internationalorganisms have promoted this congregation of scientists, scholars and biomedical engineers from Latin America and othercontinents in an environment conducive to academic exchange and professional growth.

The Latin American congresses have provided a forum to present research findings, share experiences and coordinateactivities between institutions and universities in the region to develop Bioengineering, Biomedical Engineering and relatedsciences.

The CLAIB 2016 in Bucaramanga (Santander – Colombia) followed previous meetings that were held in Mazatlan(Mexico) in 1998, Havana (Cuba) in 2001; Joao Pessoa (Brazil) in 2004, Margarita Island (Venezuela) in 2007, Havana (Cuba)in 2011, and Paraná (Entre Ríos – Argentina) in 2014. The congress program was designed so as to cover topics of regionaland international interest and to meet scientific expectations.

Around 350 scientific articles were peer reviewed, each one by three independent reviewers and members of the CLAIBscientific committee, to select those meeting CLAIB’s quality requirements. Moreover, 7 keynote talks from Europe, Asia andUnited States, and 11 keynote talks from Latin American countries were delivered by distinguished international scientists andacademic and professional discussion panels with a high impact on bioengineering/biomedical engineering. Companies andfirms also participated in CLAIB 2016 with an exposition of their innovations in the fields of medical products and equipment.Inside the activities of this congress, multiple meetings such as CORAL, IFMB, South-American working group, and social,cultural and recreation activities took place.

We thank you all for your participation in CLAIB2016 and you are always welcome to come back to Bucaramanga at anytime.

Isnardo TorresChair CLAIB2016John Bustamante

Co-Chair CLAIB2016Daniel A. Sierra

Director of Publishing and Documentation CLAIB2016

Organizations

Organizing Institutions

Sponsors

Regional Council of Biomedical Engineering for LatinAmerica/Consejo Regional de Ingeniería Biomédicapara América Latina (CORAL)

Colombian Association of Bioengineering and ElectronicsMedicine/Asociación Colombiana de Bioingenieríay Electrónica Médica (ABIOIN)

International Federation for Medical and BiologicalEngineering (IFMBE)

The IEEE Engineering in Medicine and Biology Society(EMBS)

Supporting Organizations

VIII Organizations

Organizations IX

Conference General Chair

Isnardo Torres RiveraNational PresidentProfessor Medical Physics, Biophysics and Biomimetic Colombian Association of Bioengineering and Medical ElectronicsCalle 48 # 39-59 Bucaramanga, Colombia Tel. 57 315 7267665Isnardo26@yahoo.comWeb: www.abioin.com

Conference General Co-chair

John Bustamante OsornoDirector of the Center of Bioengineering, Head of the Cardiovascular Dynamic Research Group, and Coordinator of theDoctoral Programme in Medical SciencesUniversidad Pontificia BolivarianaCircular 1ª No 73–76 Laureles, Bloque Externo 22C, Planta 2ªTel. (57/4) 448 83 88 Ext. 12400 Medellín, Colombiajohn.bustamante@upb.edu.coWeb: www.upb.edu.co

Publications and Documentation Manager, Claib 2016

Daniel Alfonso Sierra BuenoPlanning Director, UISElectrical, Electronics and Telecommunications Engineering School ProfessorUniversidad Industrial de Santander, Bucaramanga, Colombiadasierra@uis.edu.coWeb: www.uis.edu.co

X Organizations

Scientific Committee

Biosensors and Bioinstrumentation

Dr. Alejandro Weinstein, ChileDr. Alher Mauricio Hernández, ColombiaMg. Andrés Valdez Díaz, ArgentinaDr. Angel Regueiro Gómez, CubaProf. Dr. Anselmo Frizera Neto, BrasilDr. Arturo Vega González, MéxicoDr. Bertemes Filho Pedro, BrasilDr. César Antonio González Díaz, MéxicoDr. Daniel Alfonso Sierra Bueno, ColombiaDr. Diego Sebastian Grafcaride, ArgentinaDr. Edith Pulido Herrera, ColombiaMg. Eduardo Filomena, ArgentinaDr. Elisa Perez, ArgentinaDr. Fabiola Martínez, MéxicoDr. Franco Simini, UruguayM.sc. Guillermo Avendaño Cervantes, ChileDr. Henry Hermel Andrade Caicedo, ColombiaM.sc. Ing. Jaime Guillermo Barrero Pérez, ColombiaMg. Javier Enrique González Barajas, ColombiaDr. Jesus Enrique Chong Quero, MéxicoPh.D. Jhon Faber Archila Díaz, ColombiaDr. Jorge Emilio Monzón, ArgentinaDr. José María Triano, ArgentinaIng. José Pirrone Puma, VenezuelaDr. Juan Manuel Olivera, ArgentinaMg. Julio Alberto Aldonate, ArgentinaDr. Luis Enrique Llamosa Rincón, ColombiaIng. Luis Roberto Barriere, El SalvadorDr. Miguel Cadena Méndez, MéxicoDr. Myriam Cristina Herrera, ArgentinaDr. Natalia López, ArgentinaDr. Olimpia Arias De Fuentes, MéxicoDr. Omar Escalona, Reino UnidoDr. Oscar Eduardo Gualdrón Guerrero, ColombiaDr. Ricardo Silva, Venezuela/EcuadorIng. Ricardo Taborda, ArgentinaDr. Róbinson Alberto Torres Villa, ColombiaDr. Rossana Madrid, ArgentinaMg. Rubén Darío Flórez Hurtado, ColombiaMg. Sergio Conde Ocasionez, BrasilDr. Sonia Helena Contreras Ortiz, ColombiaDr. Viviana Inés Rotger, ArgentinaDr. Whisner Fraga Mamede, BrasilDr. Willian Callejas, México

Organizations XI

Biomedical Imaging and Image Processing

M.Sc. Adrián Carlos Ramón Salvatelli, ArgentinaDr. Agustina Bouchet, ArgentinaM.Sc. Alejandro Javier Hadad, ArgentinaDr. Alejandro José Uriz, ArgentinaPh.D. Alexandra La Cruz, EcuadorDr. Alfredo Corniali, BrasilDr. Ana Lía Albarracín, ArgentinaDr. Ana Beatriz Ramírez Silva, ColombiaDr. André Victor Alvarenga, BrasilMg. Andrés Valdez Dìaz, ArgentinaDr. Andrés Felipe Ruiz, ColombiaDr. Ariel Braidot, ArgentinaPost Dr. Catalina Tobón Zuluaga, ColombiaDr. Cesar a. D. Teixeira, PortugalM.Sc. Diana Estefy Gutiérrez Galvis, ColombiaDr. Diego Sebastián Comas, ArgentinaDr. Diego Sebastián Graf Caride, ArgentinaDr. Domingo Rodríguez, Puerto RicoDr. Edgar Eduardo Romero Castro, ColombiaDr. Eduardo Martínez Montes, CubaDr. Elisa Pérez, ArgentinaDr. Fernando César Coelli, BrasilDr. Gustavo Meschino, ArgentinaBioing. Gustavo Horacio Bizai Tonello, ArgentinaDr. Javier Fernando Adur, ArgentinaMg. Javier Enrique González Barajas, ColombiaDr. Jesús Enrique Chong Quero, MéxicoPost Dr. João Carlos Mendes Carvalho, BrasilMg, José Maria Triano, ArgentinaDr. José Manuel Ferrer Villena, PerúDr. José Mauricio Santos Torres da Motta, BrasilProf. Juan Enrique Suen Díaz, CubaDr. Juan Enrique Palomares Ruiz, MéxicoDr. Juan Ignacio Pastore, ArgentinaMg. Juan Manuel Olivera, ArgentinaDr. Juan Valentín Lorenzo Ginori, CubaDr. Lola Xiomara Bautista Rozo, ColombiaM.Sc. Marco Antonio Coca Pérez, ChileProf. Marlen Pérez Díaz, CubaDr. Miguel Cadena Méndez, MéxicoDr. Rossana Madrid, ArgentinaPh.D. Said David Pertuz, ColombiaDr. Sonia Helena Contreras Ortiz, ColombiaDr. Virginia Laura Ballarín, ArgentinaDr. Andrés Orozco Duque, ColombiaDr. Eduardo Peón Aves, CubaM.Sc. Edwin Santiago Alférez Baquero, EspañaM.Sc. Javier Fernando Adur, ArgentinaM.Sc. José Manuel Ferrer Villena, PerúIng. Juan Pablo Ángel López, Colombia

XII Organizations

Cardiovascular Engineering, Lung and Endocrine

Dr. Alfredo Rosado, EspañaDr. Ana María Rodríguez, ColombiaDr. Ana Milena Herrera Torres, ColombiaDr. David Alejandro Miranda Mercado, ColombiaDr. Hyxia Villegas, VenezuelaDr. Jesús Enrique Chong Quero, MéxicoDr. Jorge Emilio Monzon, ArgentinaDr. John Bustamante, ColombiaDr. Lina Marcela Hoyos Palacio, ColombiaDr. Mónica Karel Huerta, VenezuelaDr. Pedro Arini, ArgentinaDr. Ricardo Luis Armentano Feijoo, ArgentinaMg. Sandra Milena Luna Osorio, ColombiaDr. Vera Zalulich Pérez Ariza, Colombia

Molecular Engineering, Cell and Tissue

M.Sc. Ing. Alejandro Arboleda, ColombiaDr. Ana María Rodríguez, ColombiaDr. Andrés Mauricio Pinzón, ColombiaPh.D. Carolina Londoño Peláez, ColombiaDr. Diego Alejandro Velásquez Puerta, ColombiaDr. Fabián Alejandro Buffa, ArgentinaDr. Ing. Florencia Montini Ballarín, ArgentinaMg. Guillermo Carlos Campiglio, ArgentinaDr. Gustavo A. Abraham, ArgentinaDr. Juan Manuel Olivera, ArgentinaDr. Juliana Velásquez Gómez, ColombiaDr. Lizette Morejón Alonso, CubaDr. Maria Fernanda Izaguirre, ArgentinaDr. Nydia Paola Rondón Villareal, ColombiaPh.D. Pablo Cortez Tornello, ArgentinaMg. Sandra Milena Luna Osorio, ColombiaDr. Ing. Sergio Lew, ArgentinaDr. Teresita Cuadrado, Argentina

Neural Engineering and Rehabilitation

Dr. Bioing. Alfredo Corniali, BrasilDr. Lizett Morejón Alonso, CubaDr. Álvaro David Orjuela, ColombiaMg. Ing. Ana María Echenique, ArgentinaDr. Andrés Felipe Ruiz, ColombiaMg. Andrés Torres Velásquez, ColombiaProf. Dr. Anselmo Frizera Neto, BrasilPh.D. Belkys Tibisay Amador Cáceres, VenezuelaDr. Carlos Andrés Cifuentes García, ColombiaMg. Carolina Tabernig, ArgentinaDr. Clara Isabel López Gualdrón, Colombia

Organizations XIII

Mg. Claudia Bonell, ArgentinaPh.D. Daniel Lorias Espinoza, MéxicoIng. Diego Beltramone, ArgentinaDr. Edwin Alexander Cerquera, ColombiaDr. Elisa Pérez, ArgentinaMg. Guillermo Carlos Campiglio, ArgentinaDr. Jairo Lenín Ramón Valencia, ColombiaDr. Jesús Enrique Chong Quero, MéxicoPh.D. Jhon Faber Archila Díaz, BrasilDr. Jorge Letechipia Moreno, MéxicoDr. Jorge Mazzeo, ArgentinaMg. José Maria Triano, ArgentinaDr. Juan Pablo Graffigna, ArgentinaDr. Juliana Velásquez Gómez, ColombiaMg. Bioing. Luciano Schiaffino, ArgentinaDr. Luis E. Bergues Cabrales, CubaMg. Luis Eduardo Bautista Rojas, ColombiaDr. Luis Eduardo Rodríguez Cheu, ColombiaDr. María Luisa Toro Hernández, ColombiaDr. María Paula Bonomini, ArgentinaDr. Martha Zequera, ColombiaDr. Miriam Marañón Cardonne, CubaDr. Ing. Natalia López Celani, ArgentinaDr. Ricardo Silva, EcuadorDr. Vera Zasulich Pérez, ColombiaDr. Whisner Fraga Mamede, BrasilDr. Willian Ricardo Rodríguez Dueñas, ColombiaDr. Yolanda Torres Pérez, Colombia

Biomedical Signal Processing

Dr. Ing. Agustina Garcés Correa, ArgentinaDr. Ing. Alejandro José Uriz, ArgentinaDr. Alfredo Rosado, EspañaDr. Alher Mauricio Hernández, ColombiaDr. Ana Beatriz Ramírez Silva, ColombiaDr. André Victor Alvarenga, BrasilMg. Ing. Andrés Valdez Díaz, ArgentinaProf. Dr. Anselmo Frizera Neto, BrasilM.Sc. Ing. Alejandro Arboleda, ColombiaPh.D. Andrés Orozco Duque, ColombiaDr. Arturo Vega González, MéxicoDr. Carlos Julio Arismendi Pereira, ColombiaDr. Catalina Tobón Zuluaga, ColombiaDr. Cesar Alexandre Dominguez Teixeira, PortugalProf. César Augusto Aceros Moreno, ColombiaDr. Daniel Alfonso Sierra Bueno, ColombiaMg. Diana Estefy Gutiérrez Galvis, ColombiaDr. Diego Sebastián Grafcaride, ArgentinaDr. Domingo Rodríguez, Puerto RicoDr. Edith Pulido Herrera, ColombiaDr. Bioing. Eduardo Martínez Montes, Cuba

XIV Organizations

Dr. Eduardo Pedro Serrano, ArgentinaDr. Edwin Alexander Cerquera, ColombiaM.Sc. Edwin Santiago Alférez Baquero, EspañaDr. Eric Laciar Leber, ArgentinaM. en IB. Fabiola Martínez, MéxicoDr. Franklin A. Sepúlveda Sepúlveda, ColombiaDr. Gustavo Meschino, ArgentinaDr. Jairo Lenín Ramón Valencia, ColombiaMg. Javier Enrique Gonzalez Barajas, ColombiaDr. Jesús Enrique Chong Quero, MéxicoDr. Juan Carlos Perfetto, ArgentinaMg. Juan Pablo Tello, ColombiaMg. Julio César Politti, ArgentinaPh.D. Julián Luciano Cárdenas Barrera, CanadáDr. Bioing. Lorena Correa Prado, ArgentinaMg. Ing. Luis Romero, ArgentinaMg. Luis Enrique Llamosa Rincón, ColombiaDr. Luis E. Bergues Cabrales, CubaDr. Bioing. María Paula Bonomini, ArgentinaDr. Miguel Cadena Méndez, MéxicoDr. Ing. Natalia López Celani, ArgentinaPh.D. Omar J. Escalona, Reino UnidoIng. Óscar Rodolfo Vallena, ArgentinaDr. Óscar Eduardo Gualdrón, ColombiaDr. Pedro Bertemes Filho, BrasilDr. Pedro D. Arini, ArgentinaDr. Pedro Federico Diez, ArgentinaDr. Rafael Torres Amarís, ColombiaProf. Raul Correa Prado, ArgentinaDr. René Iván González Fernández, CubaDr. Robinson Alberto Torres Villa, ColombiaDr. Ricardo Silva, Ecuador/VenezuelaDr. Rubén Carlos Acevedo, ArgentinaDr. Rubiel Vargas Cañas, ColombiaPhD. Said David Pertuz Arroyo, ColombiaDr. Sergio Conde Ocazionez, ColombiaDr. Ph.D. Sonia Helena Contreras Ortiz, ColombiaDr. Verónica Medina Bañuelos, MexicoMg. Bioing. Victor Eduardo Martínez Abaunza, BrasilDr. Virginia Ballarín, ArgentinaDr. Whisner Fraga Mamede, BrasilMg. Bioing, Yanina Atum, ArgentinaDr. Yusely Ruíz González, Cuba

Bio-Micro-Nano Technologies

M.Sc. Adrian Salvatelli, ArgentinaDr. Alejandro José Uriz, ArgentinaDr. Alher Mauricio Hernández, ColombiaDr. Carlos Julio Arismendi Pereira, ColombiaDr. Diego Alejandro Velázquez Puerta, ColombiaMg. Eduardo Filomena, Argentina

Organizations XV

Dr. Eduardo A Albanesi, ArgentinaDr. Henry Hermel Andrade Caicedo, ColombiaPh.D. John Bustamante, ColombiaMg. Julio Alberto Aldonate, ArgentinaDr. Jorge Emilio Monzón, ArgentinaDr. Lina Marcela Hoyos Palacios, ColombiaMg. Luis Romero, ArgentinaDr. Marlen Pérez Díaz, CubaDr. Martha Elena Londoño López, ColombiaDr. Myriam Cristina Herrera, ArgentinaPh.D. Olimpia Arias de Fuentes, MéxicoDr. Rafael Torres Amarís, ColombiaDr. Rossana Elena Madrid, ArgentinaDr. Virginia Walz, ArgentinaMg. Bioing. Viviana Inés Rotger, Argentina

Medical Physics and Nuclear Medicine

Mg. Antonio Vélez Montoya, ColombiaDr. César Antonio González Díaz, MéxicoDr. Clara Isabel López Gualdrón, ColombiaMg. Consuelo Valera Corona, CubaDr. David Alejandro Miranda Mercado, ColombiaDr. Ernesto Suaste Gómez, MéxicoDr. Fernando Cesar Coelli, BrasilDr. Franco Simini, UruguayDr. Gabriel Ruiz, ArgentinaDr. Graciela Vélez, ArgentinaProf. Mg. Guillermo Avendaño, ChileMg. Guillermo Carlos Campiglio, ArgentinaDr. Javier Fernando Adur, ArgentinaMg. José Luis Favant, ArgentinaDr. Ing. Josefina Ballare, ArgentinaDr. Juan Enrique Suen Díaz, CubaDr. Leonardo Makinistián, ArgentinaDr. Luis E. Bergues Cabrales, CubaMg. Luis Enrique Llamosa Rincón, ColombiaDr. Marco Antonio Coca Pérez, ChileDr. María Fernanda Izaguirre, ArgentinaDr. Marlen Pérez Díaz, CubaDr. Martha Elena Londoño López, ColombiaDr. Miriam Marañón Cardonne, CubaDr. Mónica T Millares Aranda, ArgentinaDr. Pedro Bertemes Filho, BrasilDr. Ricardo Luis Armentano Feijoo, BrasilDr. Rossana Madrid, ArgentinaDr. Virginia Walz, Argentina

XVI Organizations

Biomechanics

Dr. Andrés Felipe Ruiz, ColombiaDr. Andrés Torres Velásquez, ColombiaProf. Dr. Anselmo Frizera Neto, BrasilDr. Ariel Braidot, ArgentinaDr. Arturo Vega González, MéxicoDr. Belkys Tibisay Amador Cáceres, VenezuelaDr. Carlos Andrés Cifuentes García, ColombiaDr. Clara Isabel López Gualdrón, ColombiaMg. Claudia Bonell, ArgentinaMg. Diana Estefy Gutiérrez Galvis, ColombiaDr. Diego Martín Campana, ArgentinaDr. Edith Pulido Herrera, ColombiaMg. Guillermo Carlos Campiglio, ArgentinaDr. Jesús Enrique Chong Quero, MéxicoPh.D. Jhon Faber Archila Díaz, BrasilDr. João Carlos Mendes Carvalho, BrasilDr. Jorge Ernesto Letechipia Moreno, MexicoDr. Jorge Mazzeo, ArgentinaDr. Jose di Paolo, BrasilDr. José Maurício Santos Torres da Motta, BrasilDr. Juan Enrique Palomares Ruiz, MexicoDr. Juan Pablo Ángel López, ColombiaJulio Cesar Politti, ArgentinaMg. Luis Eduardo Bautista Rojas, ColombiaDr. Luis Eduardo Rodríguez Cheu, ColombiaMg. Luis Romero, ArgentinaPh.D. Luis Vilcahuaman, PeruDr. Marco Henrique Terra, BrasilDr. Martha Zequera, ColombiaDr. Mónica T Millares Aranda, ArgentinaDr. Ricardo Luis Armentano Feijoo, ArgentinaDr. Sonia Helena Contreras Ortiz, ColombiaDr. Yolanda Torres Pérez, Colombia

Bio Robotics

Dr. Carlos Andres Cifuentes García, BrasilDr. João Carlos Mendes Carvalho, BrasilDr. John Archila Díaz, ColombiaDr. Juan Enrique Palomares Ruiz, MexicoMg. Julio Cesar Politti, ArgentinaDr. Mario Luis Tronco, BrasilDr. Manuel Betancur, ColombiaDr. Marco Henrique Terra, BrasilDr. Paulo Eigi Miyagi, Brasil

Organizations XVII

Bioinformatics – Computational Biology

M.Sc. Bio Ing. Alejandro Javier Hadad, ArgentinaDr. Andrés Mauricio Pinzón Velasco, ColombiaDr. Ariel Fernando Amadio, ArgentinaDr. Bio Ing. Eduardo Martínez Montes, CubaPh.D. Inti Anabela Pagnuco, ArgentinaDr. Julián Antonio Villamarín Muñoz, ColombiaDr. Luciano Garelli, ArgentinaDr. Luis E. Bergues Cabrales, CubaDr. María Fernanda Izaguirre, ArgentinaProf. María Margarita Goire Castilla, CubaDr. Mauricio Corredor Rodríguez, ColombiaDr. Nydia Paola Rondón Villareal, ColombiaPh.D. Ricardo Silva, Venezuela/EcuadorDr. Rubiel Vargas Cañas, ColombiaDr. Ing. Sergio Lew, ArgentinaDr. Victor Eduardo Martínez Abaunza, BrasilDr. Victor H. Castro, Argentina

Biomaterials

Dr. Alejandra Vera Álvarez, ArgentinaDr. Alher Mauricio Hernández, ColombiaDr. Andrés Ozols, ArgentinaDr. Andrés Mauricio Pinzón Velasco, ColombiaDr. Arturo Vega González, MéxicoDr. Carlos Oldani, ArgentinaDr. Carolina Londoño Peláez, ColombiaDr. Diego Alejandro Velasquez Puerta, ColombiaDr. Eduardo Peón Aves, CubaDr. Ernesto Suaste Gómez, MéxicoDr. Fabián Alejandro Buffa, ArgentinaDr. Ing. Florencia Montini Ballarín, ArgentinaMg. Guillermo Carlos Campiglio, ArgentinaDr. Gustavo A. Abraham, ArgentinaDr. Jimena González, ArgentinaDr. Ing. Josefina Ballare, ArgentinaDr. Juan Manuel Olivera, ArgentinaDr. Lina Marcela Hoyos Palacios, ColombiaDr. Lizett Morejón Alonso, CubaDr. Luis Bergues Cabrales, CubaDr. María Fernanda Izaguirre, ArgentinaDr. Martha Elena Londoño López, ColombiaPh.D. Olimpia Arias de Fuentes, MéxicoDr. Pablo Cortés Tornello, ArgentinaDr. Silvia Ceré, ArgentinaDr. Teresita Cuadrado, ArgentinaMg. Walter Pardave Livia, ColombiaDr. Whisner Fraga Mamede, Brasil

XVIII Organizations

Control and Nonlinear Systems

Dr. Álvaro David Orjuela, ColombiaDr. Andrade Kléber de Oliveira, BrasilProf. Dr. Anselmo Frizera Neto, BrasilDr. Carlos Andrés Cifuentes García, ColombiaDr. Carlos Julio Arizmendi Pereira, ColombiaMg. Carmen Telleria Prieto, CubaMg. Claudia Bonell, ArgentinaDr. Franklin A. Sepúlveda Sepúlveda, ColombiaPh.D. Jhon Faber Archila Díaz, ColombiaDr. João Carlos Mendes Carvalho, BrasilDr. José Maurício Santos Torres Da Motta, BrasilDr. Juan Enrique Palomares Ruiz, MexicoDr. Juan Manuel Gómez González, MexicoIng. Juan Pablo Angel López, ColombiaMg. Julio Cesar Politti, ArgentinaMg. Bioing. Luciano Schiaffino, ArgentinaDr. Luis E. Bergues Cabrales, CubaDr. Luis Eduardo Rodriguez Cheu, ColombiaDr. Manuel J. Betancur, ColombiaDr. Marcio José Dacunha, BrasilDr. Marco Henrique Terra, BrasilDr. Mario Luiz Tronco, BrasilDr. Paulo Eigi Miyagi, BrasilDr. Vera Zalulich Perez, Colombia

Innovation- Education Standards

Dr. Alfredo Corniali, BrasilPh.D. Andrés Orozco Duque, ColombiaDr. Angel Regueiro Gomez, CubaDr. Antonio Miguel Cruz, ColombiaMg. Carolina Tabernig, ArgentinaIng. Esp. Carolina Salazar, ColombiaIng. Esp. Diana García Peñaranda, ColombiaDr. Franco Simini, UruguayDr. Gabriel Ruiz, ArgentinaM.Sc. Prof. Guillermo Avendaño, ChileDr. Jairo Lenín Ramón Valencia, ColombiaDr. Jesús María Soto, ColombiaDr. Jose di Paolo, BrasilMg. José Luis Favant, ArgentinaDr. Juan Manuel Olivera, ArgentinaDr. Juan Pablo Graffigna, ArgentinaMg. Julio Alberto Aldonate, ArgentinaDr. Lizett Morejón Alonso, CubaMg. Luis Alfredo Rocha, ArgentinaDr. Miguel Cadena Méndez, MéxicoDr. Miriam Marañón Cardonne, CubaDr. Mónica Karel Huerta, Venezuela

Organizations XIX

Dr. Mónica T. Millares Aranda, ArgentinaIng. Óscar Vanella, ArgentinaDr. Ricardo Silva, EcuadorM.Sc. Ph.D. Rossana Rivas, PerúDr. Virginia Walz, ArgentinaMg. Bioing. Viviana Inés Rotger, ArgentinaDr. Willian Ricardo Rodríguez Dueñas, ColombiaDr. Mg. Yanina Atum, ArgentinaDr. Alfredo Corniali, BrasilPh.D. Andrés Orozco Duque, ColombiaDr. Ángel Regueiro Gómez, CubaDr. Antonio Miguel Cruz, ColombiaMg. Carolina Tabernig, ArgentinaIng. Esp. Carolina Salazar, ColombiaIng. Esp. Diana García Peñaranda, ColombiaDr. Franco Simini, UruguayDr. Gabriel Ruiz, ArgentinaM.Sc. Prof. Guillermo Avendaño, ChileDr. Jairo Lenín Ramón Valencia, ColombiaDr. Jesús María Soto, ColombiaDr. Jose di Paolo, BrasilMg. José Luis Favant, ArgentinaDr. Juan Manuel Olivera, ArgentinaDr. Juan Pablo Graffigna, ArgentinaMg. Julio Alberto Aldonate, ArgentinaDr. Lizett Morejón Alonso, CubaMg. Luis Alfredo Rocha, ArgentinaDr. Miguel Cadena Méndez, MéxicoDr. Miriam Marañón Cardonne, CubaDr. Mónica Karel Huerta, VenezuelaDr. Mónica T. Millares Aranda, ArgentinaIng. Oscar Vanella, ArgentinaDr. Ricardo Silva, EcuadorDr. Virginia Walz, ArgentinaMg. Bioing. Viviana Inés Rotger, ArgentinaDr. Willian Ricardo Rodríguez Dueñas, ColombiaDr. Mg. Yanina Atum, Argentina

Bio Prosthetic Implants (Bionics)

Dr. Lizette Morejón Alonso, CubaDr. Andrés Ozols, ArgentinaProf. Dr. Anselmo Frizera Neto, BrasilDr. Carlos Oldani, ArgentinaDr. Eduardo Peón Avés, CubaDr. Fabián Alejandro Buffa, ArgentinaDr. Luis E. Bergues Cabrales, CubaDr. Teresita Cuadrado, Argentina

XX Organizations

Medical Informatics/Science of Computing in Health - TIC

M.Sc. Bioing. Adrián Salvatelli, ArgentinaDr. Alejandro Weinstein, ChileM.Sc. Alejandro Javier Hadad, ArgentinaDr. Bioing. Alfredo Corniali, BrasilDr. Álvaro David Orjuela, ColombiaDr. André Victor Alvarenga, BrasilMg. Ing. Andrés Valdez Dìaz, ArgentinaDr. Ariel Fernando Amadío, ArgentinaDr. Carlos Julio Arizmendi Pereira, ColombiaProf. César Augusto Aceros Moreno, ColombiaDr. Daniel Ulises Campos Delgado, MéxicoDr. Diego Sebastián Grafcaride, ArgentinaProf. Eduardo Martínez Montes, CubaDr. Franco Simini, UruguayDr. Gustavo Meschino, ArgentinaLic. Inti Anabela Pagnuco, ArgentinaDr. Juan Pablo Graffigna, ArgentinaDr. Julián Antonio Villamarín Muñoz, ColombiaMg. Lola Xiomara Bautista Rozo, ColombiaDr. Luciano Garelli, ArgentinaDr. Luis E. Bergues Cabrales, CubaDr. Luis Enrique Sánchez Crespo, EspañaIng. Luis Roberto Barriere, El SalvadorMg. María Del Carmen Telleria Prieto, CubaProf. María Margarita Goire Castilla, CubaDr. María Paula Bonomini, ArgentinaProf. Maria Luiz Tronco, BrasilProf. Mónica Karel Huerta, VenezuelaProf. Paulo Eigi Miyagi, BrasilDr. Pedro Federico Diez, ArgentinaDr. Ing. Raúl Correa Prado, ArgentinaProf. René Iván González Fernández, CubaPh.D. Ricardo Silva, EcuadorProf. Roger Clotet Martinez, VenezuelaDr. Rubiel Vargas Cañas, ColombiaDr. Said David Pertuz Arroyo, ColombiaDr. Willian Ricardo Rodríguez Dueñas, Colombia

Clinical Engineering, Technology Assessment Health, Medical Devices

Dr. Alexandra La Cruz, VenezuelaDr. Bioing. Alfredo Corniali, BrasilDr. André Victor Alvarenga, BrasilMg. Andrés Valdez Dìaz, ArgentinaProf. Dr. Anselmo Frizera Neto, BrasilDr. Antonio Hernández, USADr. Antonio Miguel Cruz, ColombiaMs. Bioing. Atum Yanina, ArgentinaMg. Beatriz Janeth Galeano Upegi, Colombia

Organizations XXI

Ing. Esp. Carlos Mesa Duarte, ColombiaDr. Carlos Román Vásquez Seisdedos, CubaMg. Carmen Tellería Prieto, CubaIng. Esp. Carolina Salazar, ColombiaDr. Daniel Ulises Campos Delgado, MéxicoIng. Esp. Diana García Peñaranda, ColombiaDr. Diego Sebastián Grafcaride, ArgentinaDr. Fernando Cesar Coelli, BrasilMg. Guillermo Avendaño, ChileMg. Guillermo Carlos Campiglio, ArgentinaIng. Isabel Angélica Morales Ledezma, BoliviaDr. Jairo Lenín Ramón Valencia, ColombiaMg. Javier Enrique Camacho Cogollo, ColombiaDr. Jesús María Soto, ColombiaDr. Ing. Jorge Mazzeo, ArgentinaDr. Jose Pirrone Puma, VenezuelaM.Sc. Ing. José María Triano, ArgentinaDr. José Manuel Ferrer Villena, PerúIng. José Maria Flores, ArgentinaDr. Juan Enrique Suen Díaz, CubaDr. Juan Manuel Olivera, ArgentinaDr. Julián Antonio Villamarín Muñoz, ColombiaMg. Julio Alberto Aldonate, ArgentinaDr. Lizette Morejón Alonso, CubaMg. Luis Romero, ArgentinaPh.D. Luis Vilcahuaman, PerúMg. Luis Alfredo Rocha, ArgentinaIng. Luis Roberto Barriere, El SalvadorDr. Marcio Jose Dacunha, BrasilDr. Miguel Cadena Méndez, MéxicoDra. Miriam Marañón Cardonne, CubaDr. Mónica T. Miralles, ArgentinaDr. Myriam Cristina Herrera, ArgentinaIng. Óscar Vanella, ArgentinaIng. Raúl Romo Doña, ArgentinaDr. Renato García, BrasilIng. René Iván González Fernández, CubaDr. Ricardo Silva, EcuadorDr. Ricardo Taborda, ArgentinaDr. Roger Clotet Martínez, VenezuelaPh.D. Rossana Rivas, PerúDr. Ing. Sergio Lew, ArgentinaMg. Viviana Inés Rotger, Argentina

Mems and Microelectronics

Dr. Luis E. Rodríguez Cheu, ColombiaDr. Luis E. Bergues Cabrales, CubaDr. Miguel Cadena Méndez, MéxicoDr. Víctor H. Castro, ArgentinaDr. Yolanda Torres, Colombia

XXII Organizations

Modelling/Simulation

Dr. Alher Mauricio Hernández, ColombiaDr. Andrés Orozco Duque, ColombiaDr. Andrés Felipe Hernández Marulanda, ColombiaDr. Anselmo Frizera Neto, BrasilDr. Belkys Tibisay Amador Cáceres, VenezuelaDr. Catalina Tobón, ColombiaPh.D. Daniel Lorias Espinosa, MexicoDr. Daniel Alfonso Sierra Bueno, ColombiaDr. David Alejandro Miranda Mercado, ColombiaDr. Diego Martín Campana, ArgentinaDr. Domingo Rodríguez, Mayagüez, Puerto RicoDr. Fernando Cesar Coelli, BrasilDr. Ing. Florencia Montini Ballarín, ArgentinaDr. Franklin A. Sepúlveda, ColombiaDr. João Carlos Mendes Carvalho, BrasilDr. Jose di Paolo, BrasilIng. Jose Pirrone Puma, VenezuelaDr. Juan Enrique Palomares Ruiz, MexicoDr. Leonardo Makinistian, ArgentinaDr. Luciano Garelli, ArgentinaDr. Luis E. Bergues Cabrales, CubaDr. Manuel J. Betancur, ColombiaDr. Mauricio Corredor Rodríguez, ColombiaDr. Nydia Paola Rondón Villareal, ColombiaDr. Omar J. Escalona, Reino UnidoDr. Paulo Eigi Miyagi, BrasilDr. Ricardo Silva, Venezuela/EcuadorDr. Ing. Sergio Lew, ArgentinaDr. Virginia Walz, Argentina

Telemedicine - Health Care

Dr. Alfredo Corniali, BrasilIng. Esp. Carolina Salazar, ColombiaDr. Jose Pirrone Puma, VenezuelaMg. Ing. Juan Pablo Tello Portillo, ColombiaDr. Leandro di Presia, ArgentinaDr. Lola Xiomara Baustista, ColombiaMg. Ing. Luis Alfredo Rocha, ArgentinaDr. Luis Enrique Sánchez Crespo, EspañaDr. María Margarita Goire Castilla, CubaDr. Mónica Karel Huerta, VenezuelaDr. Paulo Eigi Miyagi, BrasilPh.D. René Iván González Fernández, CubaDr. Ricardo Silva, EcuadorDr. Roger Clotet Martínez, VenezuelaPh.D. Rossana Rivas, PerúMg. Rubén Darío Florez Hurtado, ColombiaM.Sc. Viviana Inés Rotger, ArgentinaDr. William Ricardo Rodríguez Dueñas, Colombia

Organizations XXIII

Other Topics

M.Sc. Bioing. Adrian Salvatelli, Argentina (Imágenes)Dr. Agustina Bouchet, Argentina (Logica Difusa, Matematicas)Dr. Ing. Agustina Garcés Correa, Argentina (Dosimetria, Blindajes, Radioterapia)Bioing. Alejandro Hadad, Argentina (Imag y Sistemas Expertos)Dr. Ana Lía Albarracin, Argentina (Ultrasonido, Metrología; Computer-Aided Diagnostic Systems)Dr. Ph.D. Ana Milena Herrera, Colombia (Anatomia, Fisiopatologia)Dr. Antonio Hernández, USA (Aparatos Medicos, Evaluación de Tecnologias)Dr. Bioing. Ariel Andrés Braidot, Argentina (Biomecánica E. Imagen)Mg. Beatriz Janeth Galeano Upegi, Colombia (Gestión de Mantenimiento y Activos Hospitalarios)Ing. Esp. Carlos Mesa Duarte, Colombia (Creación de Empresas de Salud)Dr. Carlos Oldani, Argentina (Biomateriales)Mg. Bioing. Carolina B. Tabernig, Argentina (Estimulacion Electric Funcional)Bioing. Claudia Bonell, Argentina (Electromiografía)Dr. Bioing. Diego Martín Campana, Argentina (Mecánica Fluidos)Mg. Bioing. Eduardo Filomena, Argentina (Electrónica Digital)Bioing. Eduardo Aldo Albanesi, Argentina (Imágenes)Dr. Bioing. Gustavo Bizai, Argentina (Microscopia y Radiones No Inozante, Biología Molecular)Mg. Bioq. Javier Fernando Adur, Argentina (Radiaciones Ionizantes)Ing. José Luis Favant, Argentina (Ingeniería Hospitalaria)Dr. Bioing. José María Flores, Argentina (Física Teoría de Modelo)Mg. Bioing. Leonardo Makinistian, Argentina (Control de Proceso)Dr. Luciano Schiaffino, Argentina (Microscopia, Biología Molecular)Dr. Víctor Hugo Castro, Argentina (Microscopia, Biología Molecular)

XXIV Organizations

Organizing Committe

Directive Board

Isnardo TorreschairJohn Bustamantevice-chair

Honor Committe

Jorge ReynoldsIgnacio Escobar

Junta Ejecutiva

Economic and Financial Affairs: Carlos MesaAcademic Oversight and Scientific Activities: Jesus Maria SotoArea scientific communications, marketing and advertising: Alejandro ArboledaExecutive Secretary on Scientific, Legal and Health aspects Marketing: Diana García

Organizers Board

Infrastructure and Logistics: Carlos ArizmendiWorkshop and Commercial Staff: Carolina SalazarGovernment and Business Management: Organization CommiteePublications and Documentation Area: Daniel A Sierra BuenoProtocol and Host Activities: Francelly BustamanteCoordination of the Green Day and extra Congress Activities-Tour operator: Delfín AlbarracínAcademic Network and Scientific Societies: Martha ZequeraScientific Comunicator: Nydia Paola RondónLogistics and Administrative Affairs: Pedro Albarracín

Organizations XXV

Students Support Committee

Universidad Autónoma de Bucaramanga

Biomedical Engineering ProgramKaren S Vega BDaniel FigueroaCarolina CarreñoDaniela MonsalveDiana Garcia RiveroMarly Galeano Blanco

Universidad Insdustrial de Santander

Andrés SuarezJuan Carlos SierraElizabeth MartinezMaria Camila PinillaMauricio BallesterosAngie Melissa Galindo

XXVI Organizations

Keynote Conferences

Regeneration Technology for Functional Musculoskeletal Tissue

October 26th, 2016 – 10:00–11:00 a.m.Auditorio Mayor Carlos Gómez Albarracín,Universidad Autónoma de Bucaramanga, Colombia

Professor James GOH: President, International Federation of Medical and BiologicalEngineering (IFMBE)PhD (1982), University of Strathclyde, Glasgow, UK; B.Sc (Hons) (1982), University ofStrathclyde, Glasgow, UK; CEng (1993), The Engineering Council, UKAppointment Status: Professor and Head, Department of Biomedical Engineering, NUS;Research Professor, Orthopedic Surgery, NUS.Professional Societies: President, Biomedical Engineering Society (Singapore); President,International Federation of Medical and Biological Engineering. Council Member, WorldCouncil of Biomechanics. Secretary General, Asia-Pacific Association for Biomechanics.Treasurer, Executive Council, World Association for Chinese Biomedical Engineers.

Secretary, TERMIS Asian Pacific chapter.

AbstractBiomaterials including polymers, hydrogels, ceramics, metals and self-assembled materials have been widely used for bone,cartilage, ligament, tendon and dental tissue regeneration. Most importantly, micro/nano- biomaterials provide some importantand interesting properties to the traditional biomaterials, including high ratio of surface area to volume, enhanced mechanicalproperties, high purity and homogeneity, and outstanding magnetic, optical and electrical properties. Taking advantagesof these novel properties, micro/nano-biomaterials can be manipulated to stimulate the chemical and structural similarities tonatural musculoskeletal tissues. For instance, cartilage is hard to be regenerated due to lack of an efficient vascular system,limited progenitor cells and chondrocyte mobility in the dense cartilage extracellular matrix. However,micro/nano-biomaterials can provide a biomimetic interface (or environment) to improve functions of chondrocyte, inhabitingand differentiation of progenitor cells. Moreover, the micro/nano-biomaterials will enhance the lifetime and performance oftissue engineered scaffolds for cartilage regeneration (such as improved mechanical properties and hierarchical structures). Onthe other hand, the development of micro/nano-biomaterials on bone regeneration is now focusing on two different directions:scaffolds for treatment of segmental defects (with structural functions) and cavity defects (such as fillers and injectablescaffolds). The utilization of micro/nano-biomaterials in orthopedic applications has been proved to be an effective andinnovative technique to enhance osseointegration and bone regeneration. The micro/nano-biomaterials also have significantimpacts on ligament/tendon regeneration. For example, nanostructured scaffolds are extremely helpful that can serve asstructural and mechanical support for cellular function and tissue regeneration. In conclusion, countless opportunities andapproaches have been brought by the development of micro/nano-biomaterials to solve the current difficulties of implantmaterials, providing lots of success for micro/nano-biomaterials in a variety of musculoskeletal tissue regenerationapplications.

A Wellness-Centric Healthcare System Interoperable with Public Health: the MultidimensionalGlobal Threats, Interdependences of the Critical Infrastructures and Geo Medicine

Keynote: October 26th, 2016 11:00 a.m. –12:00 a.m.Auditorio Mayor Carlos Gómez AlbarracínUniversidad Autónoma de Bucaramanga, Colombia

Luis Kun, Ph.D. Editor in Chief - Journal of Health & Technology - Springer - IUPESM -WHO, IFMBE Chairman Global Citizen Safety and Security WG.

Ex- Professor of National Security Affairs, CHDS/National Defense University, Fellow AIMBE,Lifetime Fellow, IEEE Editor in Chief - Journal of Health & Technology - Springer - IUPESM –

WHO. IFMBE Chairman Global Citizen Safety and Security WG, Member Developing Coun-tries WG, IEEE Society on Social Implications of Technology (SSIT) - Board of Governors, IEEELife Science Technical Committee Member, IEEE - SSIT - Distinguished Lecturer (DL) IEEE -Computer Society - Distinguished Visitor Program (DVP), IEEE - Computer Society Ad hoc PublicPolicy Committee, Member - Healthcare Transformation Ad hoc Committee, Chair, IEEE EMBS,Editorial Board.

AbstractIn the Information Age, reliance on cyberspace pervades almost every aspect of life including healthcare. Private citizens haveutilized digital systems – including the internet – to communicate with others around the globe, build social networks and shareinformation. Businesses have taken advantage of online and ecommerce to expand their client base, manage supply chains andcommunicate with customers. The United States Government relies on digital systems to collect taxes, manage criticalinfrastructure, ensure national security and interact with constituents. As one of the most connected countries on earth, theUnited States has enormously benefited from the transformations brought about by the Information Age. However, the diversebenefits of the Information Age also come with enormous risks. The Internet and other digital infrastructure are lightlyregulated and unsecure. As a “network of networks” where all types of secure government, open public and restricted privatenetworks are located, security vulnerabilities in one internet network can be used to exploit vulnerabilities in another.A growing group of state and nonstate actors, including disgruntled employees, criminals, terrorists and foreign intelligenceagencies, have exploited these vulnerabilities to maliciously target U.S. citizens, commerce and government.For over 40 years researchers have written about applying computer technologies to improve daily medical care, and in the pastdecade, the goal of using genomic data to truly personalize care has been woven into those concepts. Since 2004, the US hasfocused on creating a complete personal health record for each citizen and great strides have been made in developing thetechnical standards to allow near-realtime health data acquisition either directly from medical devices, health practitioners,caregivers, and/or patients themselves. In this period government and private agencies have also been separately collecting andorganizing vast quantities of scientific data that relate to our health. It has become clear also that many illnesses and injuries aredirectly caused or are significantly influenced by the food and water we consume, the air we breathe and the environment welive in as well as our education. Further, as human lifetimes are extended around the globe; environmental factors simply havemore years’ damage to human health and wellness. In 2009 Dr. Kun organized and conducted at the National Academy ofScience and Engineering the Transformation of the American Health Care System (https://www.hawaii.edu/csati/summit/spvg/spvg.html) from mainly a diagnostic, prognostic and therapeutic approach, to one that fosters wellness, andincorporates information and practices which seeks to advance disease prevention, and the arrest of disease manifestation inpopulations. 23 different Federal Agencies or Departments were invited as well as 30 professional organizations to representthe highly inter-disciplinary and multi-disciplinary scientific infrastructure, methods and means, which at the heart will protect,and purvey timely information to enable the implementation of the most effective and efficient medical practices for thepatient’s benefit. This vision acknowledges and asserts that the scientific community has a very large role, and a responsibilitytoward creating the fertile environment, the conditions, the means, and the practices, which can bring about much neededHealthcare transformations.

XXVIII Keynote Conferences

The globally-interconnected digital information and communications infrastructure underpins almost every facet of modernsociety and provides critical support for the economy, civil infrastructure, public safety, and national security. This technologyhas transformed the global economy and connected people in ways never imagined. Yet cybersecurity risks pose some of themost serious economic and national security challenges of the 21st Century. A growing array of state and non-state actors arecompromising, stealing, changing, or destroying information and could cause critical disruptions to U.S. systems and those ofour allies. In the face of this expanding threat, traditional telecommunications and Internet networks continue to converge, andother infrastructure sectors are adopting the Internet as a primary means of interconnectivity. Within the domain of cyberspace,nations must not only maintain an environment that promotes efficiency, innovation, economic prosperity and free trade butalso assure safety, security, civil liberties, and privacy rights. It is the fundamental responsibility of our governments to addressstrategic vulnerabilities in cyberspace and ensure that the world realize the full potential of the information technologyrevolution. Malicious cyber activity is occurring on an unprecedented scale with extraordinary sophistication. We areconfronted by nation-states, terrorist networks, organized criminal groups, individuals, and other cyber actors with varyingcombinations of access, technical sophistication and intent. Daily, elements of the U.S. information infrastructure are beingtargeted for intelligence collection, intellectual property theft, or disruption. Criminal elements are operating a pervasive,mature on-line service economy providing illicit cyber capabilities and services to anyone willing to pay. Against thisbackdrop the U.S. Government (USG) is focusing its efforts on helping the United States achieve a more reliable, resilient, andtrustworthy digital infrastructure for the future. It is working with all key players in U.S. cybersecurity, including state andlocal governments and the private sector, in a manner consistent with ensuring privacy rights and civil liberties.

Keynote Conferences XXIX

E-Health: Notable Developments, - Who: the Temple of Public Health

Keynote: October 26th, 2016 2:00 – 3:00 p.mAuditorio Mayor Carlos Gómez AlbarracínUniversidad Autónoma de Bucaramanga, Colombia

Marc Nyssen Treasurer IFMBE International Federation for Medical and BiologicalEngineering Professor Medical Informatics - Medische Informatica Faculteit Geneeskundeen FarmacieVrije Universiteit Brussel, BELGIUM

Doctor in Applied Sciences in June 1983, after defending a thesis: “New architectures foropto-electronic signal processing” (Maxima Cum Laude).Member bureau VLIR-UOS since August 2004, Chairman VLIR-UOS 2005–2009. Member of the Commission “Computermanagement” and of the Board of Directors of the “Data-center VUB-ULB”. Since January 1st 2006 to March 2008 Chairmanof the Board of Directors of the “Data-center VUB-ULB”. Affiliated with the International Union for Physical and EngineeringSciences in Medicine. Member of the “Vlaamse Toezichtcommissie” 2010–2014 (as engineer) Since September 1st 2014chairman of the “Vakgroep Geneeskunde Wetenschappen” (Public Health) at VUB, Faculty of Medicine and Pharmacy.

AbstractThe aim of this presentation is to give an overview of the operational features of e-health developments, linking the technicalbuilding blocks, available to today’s developers together in ways that enable to satisfy the requirements of the operationalpublic health systems.Constraints from the professional and legal context of modern medicine and privacy are highlighted, as well as the informationand communication tools that make it possible to realize usable systems. To have a chance for success, win-win situations mustbe created, as well for the health care professionals as for patients. Real examples illustrate successful and less successfulimplementations.Finally, the future directions towards more interaction and control by patients themselves and the impact of mobile devices areput in perspective.

XXX Keynote Conferences

A Glimpse at Emerging Innovative Cardio-Tech Solutions

Keynote: October 27th, 2016 8:00 – 9:00 a.mAuditorio Mayor Carlos Gómez AlbarracínUniversidad Autónoma de Bucaramanga, Colombia

Shankar Krishnan, Ph.D. Elected President International Federation for Medical andBiological Engineering - IFMBE. Professor & Chair. Department of BiomedicalEngineering. Wentworth Institute of Technology, Boston, USA.

Dr. Shankar Krishnan is the founding chair of the Biomedical Engineering program and anendowed chair Professor at Wentworth Institute in Boston since 2008. At NTU in Singapore, hewas the founding director of the BME Research Center and the founding head of theBioengineering division. He has served the administrative counsel of IFBME for the past ten

years, and he is presently the Secretary General of IFBME. He was elected as a Fellow of American Institute of Medical andBiological Engineering and he was a member of a team which received the CIMIT Kennedy Innovation Award in Boston.

AbstractRecent technological advancements tend to introduce innovative ways to provide better product performance in many fields,including health care applications. Heart disease and strokes cause nearly 750,000 deaths in the annually. Heart disease isconsidered to be the leading cause of death in both men and women, according to the CDC, with more 600,000 deaths annuallyin the U.S. The emerging new technological applications can provide early diagnosis and proper treatment which will bebeneficial to patients, doctors, hospitals, payers and manufacturers. These new “cardiotech” solutions are of particular interestas they are providing state-of-the-art heart disease detection and therapy significantly impacting patients, healthcare providersand the society on a whole. The objective of the presentation is to offer a glimpse at recent and upcoming innovative cardiotechsolutions.To facilitate cardiovascular disease diagnosis and therapy, numerous devices and techniques have been developed: includingECG, ICU monitors, ultrasound, CT, MR, pacemaker, ICD, and LVAD. Despite these advances, cardiovascular diseasesremain very lethal. However, recently approved devices and developing technologies aim to provide better diagnosis andtherapy to reduce the devastating effects of the cardiovascular diseases.In the following section, a few state-of-the-art emerging technologies based solutions for cardiovascular disease arehighlighted. “The Katheter” utilizes ultrasound to construct a more accurate 3-D image of the heart and provides a map ofelectrical activation of the heart. It can locate the sources of irregular heartbeats. In addition, procedures that utilize theinformation from this technology have seen improved success rates and even reduces the length of time to perform A-Fibcatheter ablation.Better monitoring systems are becoming smaller, mobile, and more convenient for clinical and in home use than ever before.Medronic’s Seeq Mobile Cardiac Telemetry system is allowing for longer monitoring, while St. Jude has developed theCardioMEMS HF system to allow for wireless monitoring of the heart. These systems are providing vital information, such asECG and heart rate that could not have been achieved before.The transformation to smart phone use allows for mobile phone to monito vital signs without needing to spend precious timewaiting at the doctor’s office. AliceCor’s Mobile ECG Clips attachment can go directly onto the phone and record, store,analyze, and transfer single-channel ECGs directly through the phone in just 30 seconds. This information can then be easilyshared with a doctor.Other newly emerging diagnostic practices include noninvasive assessment of coronary artery blockages, lipoproteinassociated CHD evaluation and the Trimethylamine-N-oxide test. These are then paired with novel monitoring technologiessuch as the Zio XT Patch, leadless pacemakers, and wearable ECG patches.

Keynote Conferences XXXI

The emergent technologies are making diagnosis and proper treatment less expensive, less time consuming, and more accurate,reducing risks and costs for all parties involved. They are paving the way for even more innovative technologies. Radical andimpossible ideas of the past may reach fruition in the future. Stem cells may be used for reconstructing myocardium andwireless charging could power the total artificial heart. All of these technologies are expected to emerge in the future and willsave lives. The multi-segmental costs associated with innovative cardiotech solutions may impose constraints and challengesbased on the health care coverage models in different countries across the globe. Efforts must be made to address and overcomethe challenges with cohesive multi-organizational and international levels and participations.In conclusion, recent cardiotech solutions prove to be promising techniques to diagnose, treat and monitor patients withcardiovascular diseases. It is anticipated that carefully coordinated interdisciplinary efforts around the globe may lead to greaterefficacies of procedures, reduced costs, reduced lengths of stay in hospitals, and improved overall outcomes and biomedicalengineers make their contributions toward inventions and implementations to enhance the quality of life.

XXXII Keynote Conferences

Emerging Trends in the Signal and Image Processing and Computer-Aided Diagnosis

Keynote: October 27th, 2016 1:30 p.m. – 2:30 p.m.Auditorio Mayor Carlos Gómez AlbarracínUniversidad Autónoma de Bucaramanga, Colombia

Andrew Laine President IEEE/EMBS Professor of Biomedical Engineering, Chair Depart-ment of Biomedical Engineering, Columbia University, New York USA. Professor of Radiology(Physics), Department of Radiology; Director, Heffner Biomedical Imaging Laboratory ColumbiaUniversity, New York, NY USA.

Andrew F. Laine is currently Chair of the Department of Biomedical Engineering and Director of theHeffner Biomedical Imaging at Columbia University and the Percy K. and Vida L. W. HudsonProfessor of Biomedical Engineering and Professor of Radiology. He was the Program Chair for the

IEEE EMBS annual conference in 2006 held in New York City and served as Program Co-Chair for IEEE ISBI in 2008 (Paris,France). He served as the IEEE EMBS Vice President of Publications 2008–2012, and currently the President of IEEE EMBS.

AbstractQuantitative Imaging Informatics in Cost effective PET Imaging and Classification of lung disease. This talk presents a novelmethod for emphysema quantification, based on parametric modeling of intensity distributions in the lung and a hiddenMarkov measure field model to segment emphysematous regions. The framework adapts to the characteristics of an image toensure a robust quantification of emphysema under varying CT imaging protocols and differences in parenchymal intensitydistributions due to factors such as inspiration level. Compared to standard approaches, the present model involves a largernumber of parameters, most of which can be estimated from data, to handle the variability encountered in lung CT scans. Themethod was used to quantify emphysema on a cohort of 87 subjects, with repeated CT scans acquired over a time period of 8years using different imaging protocols. The scans were acquired approximately annually, and the data set included a total of365 scans. The results show that the emphysema estimates produced by the proposed method have very high intra-subjectcorrelation values. By reducing sensitivity to changes in imaging protocol, the method provides a more robust estimate thanstandard approaches. In addition, the generated emphysema delineations promise great advantages for regional analysis ofemphysema extent and progression, possibly advancing disease subtyping, including COPD.An important tool for studying brain disorders is positron emission tomography (PET), a nuclear imaging technology thatallows for the in vivo functional characterization and quantification of blood flow, metabolism, protein distribution, and drugoccupancy using radioactively tagged probes (tracers). Full quantification of PET images requires invasive arterial inputfunction (AIF) measurement through online arterial blood sampling for the duration of the scan (1-2 hours). The AIF is used tocorrect images by accounting for the tracer bioavailability, which depends on an individual's physiological capacity forclearance, distribution and metabolism of the tracer. However, AIF measurement is invasive, risky, time consuming,uncomfortable for patients, and costly. Perhaps most importantly, it is impractical at the point-of-care and therefore limitsclinical utility of PET. We believe an integrative multi-modal approach is possible via the amount of personalized informationabout the physiological and biochemical makeup of individuals available in their electronic health record (EHR). This talk willoutline a novel approach to combine EHR and dynamic PET imaging data in an optimization framework based on simulatedannealing to non-invasively estimate the AIF. Techniques that will be outlined are applicable across imaging modalities,organs and diseases, such as functional imaging of prostate cancer images where increasingly more complex tracers are utilizedfor assessment and require AIF measurement.

Keynote Conferences XXXIII

Improving Prevention and Treatment of Diabetes

Keynote: October 28th, 2016 8:00 – 9:00 a.m.Auditorio Mayor Carlos Gómez AlbarracínUniversidad Autónoma de Bucaramanga, Colombia

Ratko Magjarević. Past President IFMBE Faculty of Electrical Engineering and Computing,University of Zagreb, Croatia

Ratko Magjarević received his Ph.D. in Electrical Engineering in 1994 from the University ofZagreb, Faculty of Electrical Engineering. He is full professor teaching several courses inElectronic Instrumentation and Biomedical Engineering at undergraduate, graduate and atpostgraduate studies. As visiting professor he was teaching in Stuttgart, Trieste, Ljubljana, Madridand Bogota.

R. Magjarevic is elected the President of International Federation for Medical and Biological Engineering (IFMBE) for theterm of office 2012-15. He is also the Editor in Chief of the IFMBE Proceedings series.

AbstractPatient care and management in non-communicable chronic diseases can be significantly improved by introducing of ICT toolsinto management and self-management of the disease which is recognized in the new health policies of the European Union asempowerment of the patient. WHO defines patient empowerment as “a process through which people gain greater control overdecisions and actions affecting their health”. Empowerment process should be seen both, as an individual and as a communitymeasure, bringing primarily benefits to individuals but also to the community through reduced costs.Patients with diabetes are supposed to accurately collect data such as blood glucose level, insulin doses applied, weight, dailyexercise and activity and/or blood pressure in order to be able to self-manage their disease. This paper describes a completesupport system for monitoring of patients and for remote home care based on the Personalized Intelligent Mobile HealthSystem (PIMHS) for diabetic patients. The system is based on a custom made wireless network and includes several types ofmedical, wellness or from the shelf devices that can provide information on the patient. Mobile unit is the main device formonitoring basic physiological functions, data storage and management. Peripheral devices from different manufacturers withconnectivity (e.g. glucometer, blood pressure meters, scales) or custom made sensors can be connected to the network viainterconnection devices.

XXXIV Keynote Conferences

Heart, Heart Rate, & Heart Rate Variability with Respiratory Sinus Arrhythmia

Keynote: October 28th, 2016 5:00 – 6:00 p.m.Auditorio Mayor Carlos Gómez AlbarracínUniversidad Autónoma de Bucaramanga, Colombia

Kang-Ping Lin, Ph.D. Secretary General IFMBE Distinguished Professor, Chung-YuanChristian University

He is Distinguished Professor of Electrical Engineering at Chung-Yuan Christian University,Taiwan. He served as Director of Medical Device Technology Division of the BiomedicalEngineering Center in Industrial Technology Research Institute in Taiwan (2000–2004). He wasthe president of Taiwanese Society of Biomedical Engineering (2007–2010) and the

Editor-in-Chief of the Journal of Medical & Biological Engineering (1999–2007). He is now the Director ofHe has several roles in IFMBE including the Chair of Publication Committee and Publicity Committee, the Co-Chair of AsiaPacific Working Group Committee, and the Editor of IFMBE Newsletter from 2009 to now.

AbstractAging and many diseased states have been shown to be associated with depressed vagal activity. The extent of vagaldepression correlates with the severity and poor prognosis of the disease. It will be desirable if there is physiological vagalenhancement method based on a reliable self-evaluation technology, and a tool easy to use. The tool needs to be simple, remotemonitoring capability, self-manageable and affordable. In this presentation, a handheld ECG device will be introduced for heartrate variability (HRV) analysis and respiratory sinus arrhythmia (RSA) application. Based on the device, results will show thatheart rate varies during the respiratory cycle and slowing during inspiration, which is the feature of a healthy heart andautonomic nervous system and is known as RSA, and the vagal effect of slow deep breathing increases HRV and highfrequency (HF) spectral power components in particular. Some studies concluded that the correlation between RSA and HRreflects the cardio-pulmonary coupling under parasympathetic control. In additions, because it is more convenient to measurephotoplethysmography (PPG) than ECG, PPG is supposed as a surrogate of ECG for HRV analysis. In this presentation, a fewcomparisons measured the spectrum of PRV from PPG with HRV from ECG with different breathing conditions. The resultsshowed that PRV might be used as an alternative to HRV depending on the applications and conditions.

Keynote Conferences XXXV

Semi – Keynote Conferences

EL RETO DE LA INTEROPERABILIDAD EN TECNOLOGÍAS PARA LA SALUD

Hora: 6:00 p.m. – 6:30 p.m.Fecha: Octubre 27Lugar: Auditorio Mayor Carlos Gómez Albarracín

Dr. Antonio Hernandez, EE PE. USAAntonio Hernández es un fundador y miembro del Consejo de Administración del GlobalHealth International Advisors (GHIA).Trabajó por 29 años en la Organización mundial de laSalud (OMS) como mienbro sénior de Servicios de Salud, Infraestructura Física y Tecnología.Cuenta con más de 40 años de experiencia en el campo de la tecnología de la salud y ha sidomiembro de At-Large para la Junta del American College of Clinical Engineering – ACCE.

AbstractHealthcare has experienced a fast evolution due to the convergence of information

technologies and communications with the health technologies. Medical technology in healthcare facilities is moving fromstandalone equipment to networks of medical devices (analog and digital). Technology is evolving and impacting public healthand increasing used and servicing communities. Another current trend is the use of mobile communication platforms forpersonal monitoring and auto-management of health (people responsible of their own health). In parallel to this is the evolutionof epidemiological information systems, the clinical information systems, and the information generated by the mobiletechnologies. All come together in the electronic Health records (EHR). We will highlight some aspects of the integration andconvergence of these technologies and the standard that allows the communication among information systems and medicaldevices under development by the “Integrating the Healthcare Enterprise” (IHE) initiative. This evolution and itsimplementation is impacting the operation of healthcare delivery systems and dramatically changing the workflows in thehealthcare institutions. Based on the change in the demographic indicators and epidemiological profile in Latin America andthe Caribbean population, there are challenges and opportunities to better deploy, use, and maintain these evolvingtechnologies.

XXXVI Keynote Conferences

DESAFÍOS DE LA INGENIERÍA CLÍNICA: NUEVOS ESCENARIOS DE GESTIÓN DETECNOLOGÍA MÉDICA

Hora: 6:30 p.m. – 7:00 p.m.Fecha: Octubre 27Lugar: Auditorio Mayor Carlos Gómez Albarracín

Dr. Renato García Ojeda, Brasil.

Es miembro Sénior EMBS-IEEE, del American College of Clinical Engineering - ACCE y dela Sociedad Brasileña de Ingeniería Biomédica. De 2011 a 2013 fue Presidente del ConsejoRegional de Ingeniería Biomédica para América Latina – CORAL. En 2015 recibereconocimiento de la Inter-nacional Federation for Medical & Biological Enginnering porcontribuciones como CORAL-Chair y por el IEB-UFSC el Clinical Engineering ManuscriptAward de la División de Ingeniería Clínica de IFMBE; en el primer congreso Mundial deIngeniería Clínica y Gestión de Tecnología en Salud. En la actualidad es Profesor Asociado,

Investigador y Coordinador del Instituto de Ingeniería Biomédica (IEB-UFSC) de la Universidad Federal de Santa Catarina.

AbstractDesafíos de la Ingeniería Clínica : Nuevos Escenarios de Gestión de Tecnología Medica. Las tendencias actuales de cambiosen los sistemas organizacionales de Salud en el mundo y la modificación de perfiles demográficos y tecnológicos generannuevos escenarios y desafíos.Tendencias como modelos de salud personalizada, centradas en la seguridad del paciente, métodos de gestión de enfermedadescrónicas, entre otras, incorporan necesidades de nuevas soluciones tecnológicas y de gestión, que modifican significativamentelas actividades de Ingeniería Clínica.Conceptos como Big Data, Interoperabilidad de sistemas, tecnologías pervasivas y modelos de sistemas ubicuos, determinan lanecesidad de nuevas herramientas y modelos para la Ingeniería Clínica en sus programas de Gestión de Tecnología Medica. Deesta manera, como ejemplo, herramientas como ingeniería de factor humano, modelos de toma de decisiones multiparametroscomo MCDA, gestión de procesos distribuidos, evaluación de tecnologías en salud se tornan fundamentales para la gestión detecnologías medicas. Esta presentación analiza estos nuevos escenarios discutiendo los desafíos que la Ingeniería Clínicadeberá enfrentar.

Keynote Conferences XXXVII

REGISTRO DE IMÁGENES MÉDICAS: APLICACIONES EN EPILEPSIA

Hora: 6:00 p.m. – 6:30 p.m.Fecha: Octubre 27Lugar: Auditorio de Ingenierías Jesús Alberto Rey Mariño

Dr. Juan Pablo Graffina, Argentina.

Ingeniero Electrónico, Doctor en Ingeniería, Magister en Ingeniería Biomédica y Especialista enDocencia Universitaria. En investigación ha dirigido y participado en proyectos de la UniversidadNacional de San Juan y de la Agencia de Promoción Científica y Tecnológica de Argentina, conpublicaciones en su área disciplinar y dirección de tesis y tesinas. En gestión ha sido Director del

Gabinete de Tecnología Médica (2003-2012) y autoridad del Departamento de Electrónica y Automática de la Facultad deIngeniería de la Universidad Nacional de San Juan (2012 a la fecha). Actualmente es Presidente de la Sociedad Argentina deBioingeniería (2015 a la fecha).

AbstractThe neurophysiology requires different equipment and studies for increasingly complex diagnosis. The pathologies areapproached from anatomical, functional and metabolic information from different modalities. Epilepsy is a chronicneurological disorder that requires a variety of diagnostic techniques for the location of the epileptic area. In some cases,Magnetic Resonance Imaging (MRI) seems to be the technique of choice because it allows extraordinary precision to locate theanatomical area responsible of irritative focus. However, the seizure focus does not always coincide with a structural alteration,and in such cases functional imaging techniques such as Single Photon Emission Computed Tomography (SPECT) andPositron Emission Tomography (PET) are recommended. In addition, there are other complex techniques as Tractography,Functional Connectivity, Electrical Maps, etc.Medical Image Modalities have different reference frameworks and theirs fusion requires adjust position and applied differenttransformations. Registration is defined as a process to transform mobile volume(s) in same framework of fixed volume.Maintz [1998-2016] proposed different categories for analysis of Registration Process.Conference describes a basis of Registration and its application to different examples with epileptic patients. First part exposestheoretical description to calculate optimal transformation and classic evaluation functions. Calculation depends of differentfactors: Modalities, Anatomic parts, etc.In second part, some cases are presented with epileptic patients. Different problem associated to registration and its solution isshown. These include: MRI-fMRI, MRI-Tractography, MRI-CT, MRI-Atlas, Medical Volumes-Patient applied toneuronavegation, MRI-SPECT, MRI-PET-Tractography, MR-Tractography-Electric Map, and so on.As conclusion, references and main ideas are presented as summary of presentation.

XXXVIII Keynote Conferences

LA FORMA DE LOS ÁTOMOS EXPLICARÍA EL FUNCIONAMIENTO DE ESTRUCTURASORGÁNICAS COMPLEJAS

Hora: 6:00 p.m. – 6:30 p.m.Fecha: Octubre 27Lugar: Auditorio Menor Alfonso Gómez Gómez

DE LA FORMA DE LOS ÁTOMOS AL CÓDIGO OCULTO DEL ADN

Hora: 6:30 p.m. – 7:00 p.m.Fecha: Octubre 27Lugar: Auditorio Menor Alfonso Gómez Gómez

Jaime Delgado Avendaño, Bucaramanga, Colombia.Físico y matemático, Universidad de Pamplona. 40 años de experiencia como profesor de físicaPublicaciones: UNIFICACIÓN DE LA FÍSICA, (Primera Aproximación). 1976; MAS CERCA DELCIELO, (Ecuación de Órbita). 2003 y FISICANOVA, (Una Aproximación a la Realidad). 2008

AbstractFISICANOVA es un conjunto de teorías acerca de las fuerzas fundamentales, que intentan unaaproximación a la realidad, basadas en la concepción de un Universo formado por minúsculasburbujas tangentes, cuyo interior e intersticios son vacío absoluto, que se colapsan para formarpartículas materiales que deforman el espacio circundante originando campos de energía. Esta sencillaconcepción del Universo permite explicar los fenómenos naturales que van desde lo más pequeñohasta lo más grande: Desde la más pequeña de las partículas subatómicas hasta el más grande de los

agujeros negros, de una manera elegante y coherente sin recurrir a definiciones abstrusas e imposibles. Del estudio de estasteorías se desprende que los átomos tienen formas particulares que les confieren sus propiedades físicas y químicas, de talmanera que sus compuestos y cristales están organizados en arreglo a dichas formas. En su aplicación a la Bioquímica,FISICANOVA muestra cómo la forma de los átomos es decisiva al momento de explicar el funcionamiento de estructurasorgánicas complejas como la Hemoglobina, la Cobalamina, ADN y ARN entre otras. FISICANOVA abre una puerta paraaplicaciones médicas y tecnológicas que permitirán el mejoramiento de la calidad de vida física, emocional y social del serhumano.

Keynote Conferences XXXIX

MEDICIONES PSICOFISIOLÓGICAS INSTRUMENTALES, UN CAMPO EMERGENTEDE LA INGENIERÍA BIOMÉDICA

Hora: 1:30 p.m. – 2:00 p.m.Fecha: Octubre 28Lugar: Auditorio Mayor Carlos Gómez Albarracín

Dr. Guillermo Avendaño, Chile.

Presidente de CORAL. Académico e investigador de la Escuela de Ingeniería Civil Biomédicade la UV. Ingeniero Ejecución Electrónico, U. Norte, Chile; Magister en Educación Ambiental,UPLA, Chile. Áreas de Desarrollo: Bioinstrumentación. Líneas de Investigación: Psicofi-siológica, Radiometría, Simulación de procesos biofísicos y equipos médicos.

AbstractEntre los equipos que en la actualidad se utilizan para realizar mediciones de procesos

encefálicos, están los conocidos con herramientas psicofisiológicas, las cuales presentan como principal característica, ser defácil utilización, baja o nula invasividad y un costo mucho menor que cualquier otro dispositivo bio-instrumental usados en lamedición encefálicas como los electroencefalógrafos, potenciales evocados o los complejos equipos de imagenología, almismo tiempo son más eficaces y eficientes que los test o escalas psicológicas convencionales.Sus principales aplicaciones son, estudiar procesos encefálicos relacionados con el aprendizaje humano, todos los fenómenosencefálicos originados por las cargas psíquicas como el Stress, Burn Out y los trastornos del comportamiento afectivo social,trastornos del procesamiento cognitivo, detección de alteraciones de las llamadas funciones ejecutivas, F.E.En psicofisiología se utilizan exitosamente, medidores de Tiempo de Reacción simples y complejos, medidores de Umbral deDiscriminación Táctil (Estesiómetros), medidores de Frecuencia Crítica de Fusión (Flicker), sistemas de Biorealimentación(Bio Feedback), Medidores de tremor muscular mecánicos (Peeple), medidores de Coordinación motora (MAINS) y otros denaturaleza similar.Se han diseñado, construido y aplicado a niños escolares, un conjunto de varios equipos que nos han permitido obtener útilesresultados verificando o refutando diagnóstica en Trastorno de Déficit Atencional con Hiperactividad y desorganizaciónvisoespacial

XL Keynote Conferences

TENDENCIAS EN LA BIOMECÁNICA CLÍNICA Y DEPORTIVA

Hora: 1:30 p.m. – 2:00 p.m.Fecha: Octubre 28Lugar: Auditorio de Ingenierías Jesús Alberto Rey Mariño

Ph.D. Ariel Braidot, Argentina.

El PhD Bioingeniero Ariel Braidot se ha especializado en aplicaciones clínicas y deportivas de labiomecánica en los últimos años. Se desempeñó como Presidente, Vicepresidente y Comisión directivade la Sociedad Argentina de Bioingeniería-SABI-.2003-2013. Director de la Investigador Asistente,Becarios de Posdoctorado y Doctorado del CONICET y Maestría. Evaluador de Proyectos AcadémicosY Tecnológico. Director de Proyectos de Investigación Y Cooperación nacionales e internacionales.

Responsable de Convenios de Colaboración con Instituciones nacionales e internacionales. Director Académico, CoordinadorAcadémico, de la Maestría en Ingeniería Biomédica, FI-UNER. Presidente de la comisión de Comisión de Extensión eInvestigación. 2006-2016. Director y Subdirector del Departamento Bioingeniería de la Carrera Bioingeniería y Bioinformáticade la FI-UNER. Integrante del Banco de Evaluadores de CONEAU desde 2012, Par evaluador en las Carreras deBioingeniería/Ingeniería Biomédica en 2015. Director del Laboratorio de Biomecánica de la FI-UNER. Posee publicacionesinternacionales en revistas, libros, capítulos y eventos científicos. Participó como responsable del dictado de cursos de grado yposgrado para carreras de Grado, Maestría y Doctorado de Bioingeniería/Ingeniería Biomédica.

AbstractDesde sus inicios el análisis biomecánico ha tenido su mayor desarrollo en el área de mejoras en patologías del movimiento.Específicamente, la marcha es el gesto más común que se ha estudiado desde hace varias décadas. También tiene un menordesarrollo el análisis del movimiento aplicado a patologías del miembro superior, en este aspecto uno de los gestos máscomunes es alcanzar y agarrar un objeto con la mano, actividad ampliamente empleada en actividades de la vida diaria.El análisis del movimiento de gestos deportivos es más reciente. En este aspecto se ha fortalecido el estudio de atletas de elitetanto para la mejora en la técnica específica como en la valoración de posibles lesiones futuras, empleando así el análisisbiomecánico como una herramienta de predicción.Para lograr un adecuado análisis biomecánico se requiere el desarrollo de herramientas de modelado y estimacionesantropométricas con la mejor precisión posible. Como ejemplo, se presentan las herramientas de desarrollo de modelosbiomecánicos aplicados a gestos deportivos de interés. Se analizan estos nuevos ejemplos de aplicación considerando que unamejora en la calidad de los gestos tanto en deportistas profesionales de elite como jugadores amateurs permitirá fomentar unmejor desarrollo del deporte en forma continua. Además contribuirá a disminuir lesiones, lo que sin duda significa una mejoraen la calidad de vida y social de la población.

Keynote Conferences XLI

IMPLANTES CARDIOVASCULARES A LA LUZ DE NUEVAS TÉCNICAS Y MATERIALES

Hora: 2:00 p.m. – 2:30 p.m.Fecha: Octubre 28Lugar: Auditorio de Ingenierías Jesús Alberto Rey Mariño

Dr. John Bustamante, Colombia

Médico y Cirujano de la Universidad Pontificia Bolivariana/Ph.D. en Cardiología de la UniversidadAutónoma de Barcelona/Post-Ph.D. en Prótesis y Bioimplantes Cardíacos del Instituto Nacional deCardiología de México. Director del Grupo de Investigación de Dinámica Cardiovascular de laUniversidad Pontificia Bolivariana/Coordinador del Programa de Doctorado en Ciencias Médicas y

Director del Centro de Bioingeniería de la misma Universidad. Investigador Sénior, vinculado a múltiples proyectos deinvestigación en el área cardiovascular, en los temas de: prótesis e implantes, biomateriales, biomecánica, instrumentación,modelización y simulación; de los cuales se han publicado varios textos y artículos científicos. Desarrollador de dos patentesde invención de dispositivos cardiovasculares. Miembro de la Sociedad Colombiana de Cardiología y Cirugía Cardiovascular:Comité Científico y Comité de Arbitraje de la Revista Colombiana de Cardiología. Miembro Honorario Federación Argentinade Cardiología: Moderador Mesa Temática “Foro Falla Cardiaca (Heart Failure Forum)”. Fellowship de la InteramericanSociety of Cardiology. Miembro de la Junta Directiva de la Asociación Colombiana de Bioingeniería ABIOIN, y ExPresidentedel Capítulo ACOBIAN; Miembro del Comité Editorial, Científico y de Arbitraje, en varias revistas indexadas de caráctercientífico internacionales y nacionales.

AbstractMúltiples alteraciones estructurales del corazón y el sistema vascular traen como consecuencia disfunciones en la accióncirculatoria; dependiendo de la severidad de tal lesión llega a ser necesario el reemplazo o la intervención sobre algunasestructuras anatómicas por medio de diferentes implantes que pueden ser de tipo biológico o sintético. Las posibilidadesabiertas con la incursión de diferentes biomateriales, con gran compatibilidad biológica y excelentes comportamientosbiomecánicos, permiten disponer en la actualidad de una variedad de elementos para el manejo quirúrgico de pacientes condiversas patologías cardiovasculares, incrementando su calidad de vida.Los biomateriales de uso cardiovascular surgen de los desarrollos de nuevos materiales, mediante procesos expeditos quebrindan nuevas texturas, diversos comportamientos mecánicos y tolerancias al esfuerzo y a la agresión histoquímica, lo quegarantiza un adecuado comportamiento al ser implantados en el organismo humano.En la presente conferencia se presenta la dinámica de estas mejoras que propenden en alcanzar una mejor operatividad, asícomo una mayor adaptabilidad del tejido biológico, lo que redunda en la funcionalidad y duración de la prótesis, reduciendo laaparición de falla primaria. Se ilustran los medios de evaluación de dispositivos cardiovasculares, mediante ensayos debiocompatibilidad en modelos in vitro de células cardiacas valorando su capacidad proliferativa y generación de sincitios queinteractúan con el implante, así como diferentes bancos de ensayos cardiovasculares, facilitando la valoración objetiva ypermitiendo determinar si son aceptables para su uso clínico.El impacto de los proyectos que se enmarcan en la disposición de dispositivos que permiten la introducción de nuevas prótesiscardiovasculares en el mundo de esta especialidad médica, han de repercutir también en el ámbito social hacia una altadisponibilidad, buena calidad y menores costos.

XLII Keynote Conferences

NEFRO-RED: UN NUEVO CONCEPTO DE GESTIÓN PARA HEMODIÁLISIS

Hora: 1:30 p.m. – 2:00 p.m.Fecha: Octubre 28Lugar: Auditorio Menor Alfonso Gómez Gómez

Dr. Miguel Cadena Méndez, México.

El Dr. Cadena trabaja en la Universidad Autónoma Metropolitana-Unidad Iztapalapa (UAM-I),desde 1974, adscrito desde el 2003 al Centro de Investigación en Instrumentación e ImagenologíaMédica, (www.ci3m.mx) en la Cd. de México. Egresó como Ingeniero (IPN-ESIME, 1965-1968,México), y realizó estudios a nivel maestría (WU, 1978-1980, EUA) y a nivel doctorado (UNAM,2002-2005, México). Es profesor fundador de la licenciatura y posgrado en Ingeniería Biomédicade la UAM-I (1974 y 1982). Vicepresidente y Presidente SOMIB (1994–1997) y CORAL (2005–2010). Medalla al Mérito Universitario por la UAM-I (2012) y socio honorario por la IFMBE(Canadá, 2015).

Keynote Conferences XLIII

A New Model for Hemodialysis Management

Miguel Cadena-Méndez, Emilio Sacristán-Rock, Fabiola Martínez-Licona and Joaquín Azpiroz-LeehanResearch Center for Medical Imaging and Instrumentation (www.ci3m.mx)EE Department, Universidad Autónoma Metropolitana-Iztapalapa, México City.mcm@xanum.uam.mx

RESUME

Purpose:The aims in this semi-plenary are to explain: (a) how lethal rates (20-30%) in hemodialysis clinics is incremented when theirmanagement models are oriented to reduce operational costs in the treatment processes. The high operational costs and the lowpayment per treatment push clinics to reduce expenses in quality control (QC) such that they produce high rates of intradialytichypotension (30-40%), and (b) how clinics using a different model based in business processes management (BPM), which isoriented to preserve patients’ homeostasis, can reduce operational costs 35% and improve QC in order to reduce hypotensionevents (10%) and lethal rates (5%).

Background:The problem is the unacceptable lethal rates (20-30%) in 65% in outpatient’s clinics in México. The aims are to reduceintradialytic hypotension events and operational costs to finally reduce lethal rates. Today, the management models in clinics &hospitals for hemodialysis are oriented according to the QC suggested by the KDOQI guidelines (Kt/V> 1.2). However, thisstandard is not enough to assure high performance in clinics’ processes. The health care delivery system in México togetherwith the supplier companies have generated wrong business-rules. These rules are based in the “pay per treatment or pay perevent” model. Public bidding contracts squeeze amounts of payment per treatment up to 65±10 USD. The indirectconsequence is that public and private clinics unnecessarily work in unethical manner for profit: (1) reducing QC costs until $5since supplies and overhead costs are approximately 50±5 USD/treatment, and (2) reducing treatment’s time to 2.5 hours inaverage instead using 3.5 hours since they look for the treatment of the “third patient” in 8 hours shifts to generate positivereturn margin, and (3) reducing the hemodialysis services offer to only 13% of the total ESRD prevalence (200,000patients/year) to unbalance demand vs offer index. The deplorable consequences are: (4) high rate of intradialytic hypotensionevents (30-40%), (5) high lethal rates of 200-300 deaths in 145,000 treatments per year, and (6) poor benefits for allstakeholders involved since an assessment study in 79 outpatient clinics (Malaquias et al, UNAM-2009) showed that 65%of the clinics run under improper QC performance.

Methodology Approach:The targets in the BPM model were defined as: (a) to reduce up to 10% the hypotension rate which is equivalent to reduce up to5% the lethal rate, (b) to reduce treatment operational costs 35%, and (c) to increase 300% the costs devoted to QC equivalent to20 USD/treatment. Then, the new aim was defined as: “the more patient’s homeostasis is preserved at long time, the lessoperational costs are generated”. Then, the outputs and outcomes from the BPM model were defined as: less medical consults,less laboratory tests, less use of chronic pharmaceutical prescriptions (EPO, kelants, vitamins, anti-hypertensives, etc), betterhemoglobin levels (10-12 gr/dl), better albumin levels (4-5 gr/dl) and the most important, more patient’s quality of life.The BPM modeling and operational processes were designed in three phases: first, the “what’s” were defined in an assessmentprocess “as is” in standard clinics. Second, the benefits were defining mapping decisions and actions in the “who’s” and“how’s” silos were defined in such a manner that QC process were based in a sequence of homeorhesis state variablesmeasurement along each treatment: (a) energy expenditure with metabolic substrates, (b) cardiac simpatho-vagal index and(c) hydric composition. All these physiological variables were measured as a response to changes of multiple factors: (1) UFRby hemodiafiltration (HDF), (2) PO4 clearance, (3) dialysate temperature control, (4) intradialytic exercise, (5) reuse ofdialyzer filters, and (5) nutritional support. The impact of this new BPM model was partially proved by multiple pilot studies atthe National Cardiology Institute Ignacio Chavez, México City, in patients under preparation to receive kidney transplants.

Findings:The costs for QC process were incremented up to $20 USD per treatment reducing up to 12% the hypotension events.

XLIV Keynote Conferences

IMPACTO DE LAS NUEVAS TECNOLOGÍAS BIOMÉDICAS EN EL FUTURO DE LAMEDICINA

Hora: 2:00 p.m. – 2:30 p.m.Fecha: Octubre 28Lugar: Auditorio Menor Alfonso Gómez Gómez

Dr. Jorge Reynolds, Colombia.

El trabajo de Dr. Reynolds ha sido valorado mundialmente. Es miembro de 42sociedades científicas en Colombia y el exterior; en algunas de ellas como miembrohonorario. Es miembro de la Academia de Ciencias de Nueva York desde 1989,miembro de la Academia Colombiana de Ciencias Exactas, Físicas y Naturalestambién desde 1989 y miembro Asociado de la Academia Nacional de Medicinadesde el año 2004. También es miembro fundador de varias sociedades científicas.En el 10 de noviembre de 2015 recibió el doctorado Honoris Causa por parte de laUniversidad de La Sabana, en reconocimiento de sus 55 años investigativos en elfuncionamiento eléctrico del corazón.

Keynote Conferences XLV

Precongress Courses

October 25th, 2016 Duration: 4 Hours

Curso Profesor Lugar/Hora

Aplicaciones Clínicas de laBioimpedanciometría

Prof. Dr. Ing. Franco Simini Auditorio Facultad de Medicina UNAB8:00 a.m. – 12:00 m

La Nanotecnología en la Bioingeniería Lina Marcela Hoyos Palacios Universidad Pontifica Bolivariana BloqueK

8:00 a.m. – 12:00 m2:00 p.m. – 6:00 p.m.

(Continued)

(Continued)

Curso Profesor Lugar/Hora

Prospectiva de la Ingeniería derehabilitación y tecnologíabiomédica para la discapacidad

Dr. Rafael Kohanoff Laboratorio de Electrónica UNAB8:00 a.m. – 12:00 m

Prof. Mario Aguilar

Análisis de Micro potencialesCardíacos en Registros ECG de AltaResolución

Prof. Eric Laciar Leber Universidad Autónoma de BucaramangaUNAB

2:00 p.m. – 6:00 p.m.

(Continued)

Precongress Courses XLVII

(Continued)

Curso Profesor Lugar/Hora

Aplicaciones en la BiomecánicaClínica y Deportiva

Dr. Ariel Braidot Universidad Autónoma de BucaramangaUNAB

2:00 p.m. – 6:00 p.m.

Diseño Curricular en IngenieríaBiomédica

Dr. Joaquín Azpiroz Leehan Universidad Autónoma de BucaramangaUNAB

2:00 p.m. – 6:00 p.m.

Procesamientode Imágenes deMicroscopía

Virginia Ballarin Universidad Industrial de Santander U.I.S8:00 a.m. – 12:00 m

Juan Ignacio Pastore

XLVIII Precongress Courses

Academical Workshops

OCTOBER 26th, 2016 Duration: 4 Hours

Curso Profesor Lugar/Hora

Taller de Educación en Ingeniería Biomédicay Bioingeniería

Jesús María Soto Director Del Taller Universidad Autónoma deBucaramanga UNAB

3:00 p.m. – 6:30 p.m.

Taller de Innovación y DesarrolloEmpresarial

Carolina Salazar Andres Orozco Universidad Autónoma deBucaramanga UNAB

3:00 p.m. – 6:30 p.m.

Workshops XLIX

Clinical Workshops

October 26th, 2016

Engineering Workshop Hospital and/or Clinic

International FoscalWith the participation of Professor Marc Nyssen Treasurer IFMBE Universiteit Brussel, Belgium

Workshop of Social Projection of the Disability’S Technology

With the participation of Professor James GOH: President, IFMBE. Conference Jean Marc Van Hissenhoven, chief scientistMobility Group “High technology and rehabilitation.”

Clinical Engineering and/or Hospital Engineering

FCV INTERNATIONAL HOSPITAL.Organized by Jaime Poveda and Carlos Mesa

Workshop on Education in Bioengineering and Biomedical Engineering

Organized by Jesús María Soto - Universidad EIA (Medellín, Antioquia)

Workshop on Innovation and Business Development

Organized by the Medellin Metropolitan Institute (ITM), led by medical equipment companies in UNAB

IFMBE – Industry Working Group Symposium at the CLAIB 2016

From 9:00 am to 12:00 m. Venezuela Room, UNAB Hostal

“Successful cases of research, innovation and transfer technology to promote a link between the scientific community,industry and health service providers”

Speakers:

• Prof. Piotr Ladyzynski, Poland.• Prof. Martha Lucía Zequera Díaz, Colombia.• Prof. Paulo Carvalho, Portugal.• Prof. Ratko Magjarevic, Croatia.• Ing. Bladimir Guzmán Páez, Colombia.• Prof. Gina Paola Flórez, Colombia.• Dr. Héctor Castro, Ministerio de Protección Social, Colombia.

L Workshops

Participants in Innovation and Bussiness Development Fair

1. Materialise Colombia S.A.S.http://www.materialise.com/

3. Medinistros S.A.S.www.medinistros.com

2. Advanced Instruments S.A.S.www.advanced.com.co

4. Set & Gad S.A.S.http://setgad.com/

Workshops LI

Contents

A System to study the Evolution of Cardiac Arrhythmias at Home . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1R.I. Gonzalez-Fernandez, M.L. Mulet-Cartaya, J.D. Lopez-Cardona, A. Lopez-Reyes, O. Canto-Hernandez,E. Ledesma Valdes, V. Rodríguez-Peraza, P. Gonzalez-Acosta, and M. Gomez-Florido

Implementation of risk management activities within a quality management system.An osseous adhesive as case study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

R.M. Guerra Bretaña, M.C. Pérez Álvarez, M.S. de Almeida, and L.A. de Sena

Estimation of the optimal maintenance frequency of medical devices: A Monte Carlo simulation approach . . . . . . . 9Antonio Miguel Cruz and William Ricardo Rodriguez Dueñas

A visual EEG epilepsy detection method based on a wavelet statistical representation and the Kullback-Leiblerdivergence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13

A. Quintero-Rincón, M. Pereyra, Carlos D’Giano, H. Batatia, and M. Risk

First Steps For A Web-Based Platform Oriented To The Study Of The Infant Neuro-Development And Disability . . . 17Sergio D. Cano Ortiz, Zoila Gonzales Videaux, Amilcar Borrás Gonzalez, Reinhardt Langmann,Hartmut Haehnel, and Ludmila Regueiferos Diaz

How do our students learn clinical engineering? A pilot study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22Antonio Miguel Cruz, Daniel Alejandro Quiroga Torres, Ana Maria Presiga, and Nestor Flórez Luna

An Embedded Hybrid BCI Speller . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26P.A. García, E.M. Spinelli, and G.M. Toccaceli

Teaching maintenance of medical devices in simulation centers: a pilot study . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30Daniel Alejandro Quiroga Torres, Antonio Miguel Cruz, Ana Maria Presiga, and Nestor Flórez Luna

Biofunctionalization Process of a-SiC:H Surfaces Applied to an Interdigitated MicroelectrodeArray to Detect Enterotoxigenic Escherichia coli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34

José Herrera-Celis, Claudia Reyes-Betanzo, Abdu Orduña-Díaz, Ana Pérez-Coyotl,Armando Hernández-Flores, Janet Morales-Chávez, and Arely Culebro-Gomez

Dofetilide effect on human atrial action potential under normal and atrial fibrillation conditions. In silico study . . . . 38C. Tobón, S. Pérez, J.P. Ugarte, and J. Saiz

Architecture of an emotion recognition and video games system to identify personality traits . . . . . . . . . . . . . . . . . 42M. Callejas-Cuervo, L.A. Martínez-Tejada, and J.A. Botero-Fagua

Classification of Weight Status Using Anthropometric and Clinical Indicators. . . . . . . . . . . . . . . . . . . . . . . . . . . . 46A.E. Martinez-Licona, F.M. Martinez-Licona, J.C. Romero-Macias, and L.A. del Castillo-Alfaro

How Can Biomedical Engineering and Health Science Students Learn Together? . . . . . . . . . . . . . . . . . . . . . . . . . 50W.R. Rodríguez, A.M. Ríos, and A. Miguel Cruz

Effect of Light Scattering due to Multilamellar Bodies in the Human Eye . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54Emilia M. Méndez-Aguilar, Ismael Kelly-Pérez, and L.R. Berriel-Valdos

Formalization of Gene Ontology relationships with factor graph towards Biological Process prediction . . . . . . . . . . 58F. Spetale, P. Bulacio, F. Krsticevic, S. Ponce, and E. Tapia

Ultrasound stimulation of insulin release from pancreatic beta cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62I.M. Suarez Castellanos, B. Balteanu, Tania Singh, A. Jeremic, and V. Zderic

Lead (Pb++) effect on human atrial action potential under normal and atrial fibrillation conditions. In silico study . . . 66C. Tobón, D. Pachajoa, J.P. Ugarte, and J. Saiz

Acoustic spectrometer: resonant sensing platform for measuring volumetric properties of liquid samples . . . . . . . . . 70S. Villa-Arango, R. Torres, P.A. Kyriacou, and R. Lucklum

Rehabilitation Equipment For Rotator Cuff Injuries Shoulder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74Hedrick ROBLES, Andrea SALAMANCA, Valentín MOLINA, and Horderlin ROBLES

An overview on biological effects of trace-element in substituted calcium phosphates . . . . . . . . . . . . . . . . . . . . . . 78R.M. Guerra Bretaña, J.R. Guerra-López, and L.A. de Sena

Trading barriers in the medical devices industry. Are these barriers hindering the developmentof this sector in Cuba?. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82

Y. Chaveco Salabarria, J.C. Rubio Romero, and R.M. Guerra Bretaña

A risk-based integrated management for patient safety and quality in healthcare services . . . . . . . . . . . . . . . . . . . . 86R. Roque González, R.M. Guerra Bretaña, Y. Chaveco Salabarria, K.F. Ortiz Jaya, and O. Vera Cabezas

CAMACUA: Low Cost Real Time Risk Alert and Location System for Healthcare Environments. . . . . . . . . . . . . . 90I. Decia, A. Farías, D. Szerman, L. Grundel, D. Briatore, M. Piñeyrúa, A. Villar, and F. Simini

Pupillary Latency in Chromatic High speed Video-oculography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94Sánchez S. Anabel and Suaste G. Ernesto

Pressure Monitor in Endotracheal Cuff for Effective Intubation of Patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98S. Villa-Arango, E. Mejía-Mejía, J.M. Gómez, S. Uribe, and R. Torres

Simultaneous detection of the position of eye movements and head for diagnostic purposesof the vestibular system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 102

G. Palomino-Roldán, E. Suaste-Gómez, and A. Castañeda-Galván

Biomedical Engineering in Latin America: A Survey of 90 Undergraduate Programs. . . . . . . . . . . . . . . . . . . . . . . 106J. Azpiroz-Leehan, F. Martínez-Licona, E.G. Urbina-Medal, M. Cadena M., and E. Sacristán Rock

Continuous body temperature monitoring system based on a flexible PPy/PLA wristband . . . . . . . . . . . . . . . . . . . 110G. Rodríguez-Roldán and E. Suaste-Gómez

Fall detection system for elderly by MEMS accelerometer and SMS alert . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114E. Oporto and L.A. Vilcahuaman

Plastic Casing in Medical Equipment: Evaluation of 3D Design and Molding Simulation . . . . . . . . . . . . . . . . . . . . 118M. Gómez, Y.H. Villalta, J.E. Suen, and R.I. González

Automatic ABR detection at near-threshold intensities combining template-based approach and energy analysis . . . . 122I.M. Cabana-Pérez, E. Velarde-Reyes, A. Torres-Fortuny, E. Eimil-Suarez, and A. García-Giró

Comparative Study of Robust Methods for Motor Imagery Classification based on CSP and LDA . . . . . . . . . . . . . 126Ana Julia Villar

CINARTRO: Clinical Tool to Assess Knee Kinematics by Videofluoroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130Williams Olivera, Marcio Rodriguez, Darío Santos, and Franco Simini

LIV Contents

Test Bench to Validate Audio CODEC Kit as EIT Complex Voltage Measurement Circuit . . . . . . . . . . . . . . . . . . 134M. Arregui, E. Santos, and F. Simini

Images Digitization and Characterization of Surface and Fundus obtained through a Slit Lamp Adapted . . . . . . . . . 137I. Cassi, A. Salvatelli, G. Bizai, A. Hadad, D. Ramírez Arduh, and B. Drozdowicz

Non-homogeneous multichannel electroencephalographic dynamic forward modeling of epilepsy . . . . . . . . . . . . . . 141P.A. Munõz-Gutiérrez and E. Giraldo

Discovery of novel dihydroorotate dehydrogenase inhibitors in trypanosomatids through a molecular dockingand molecular dynamics approach . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145

Rodrigo Ochoa, Carlos Muskus, and Maria Luisa Serrano

Space Adventures: a serious game for childhood obesity prevention . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149L.M. Parra Navarro, D.R. Paez Ardila, M.M.S. Pires, and J.L.B. Marques

Cardiac dynamic assessment through entropy proportions and probability. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 153Javier Rodríguez, Leonardo Ramírez, Signed Prieto, and Catalina Correa

Automatic Detection of the Retroareolar Region in X-Ray Mammography Images . . . . . . . . . . . . . . . . . . . . . . . . 157Germán F. Torres and S. Pertuz

Improved Particle Swarm Optimization algorithm applied to rigid registration in medical images . . . . . . . . . . . . . . 161Ramiro Isa Jara, Francisco J. Buchelly, Gustavo J. Meschino, and Virginia L. Ballarin

Assessment of Surface Electromyography During Orofacial Praxis in Healthy Subjects . . . . . . . . . . . . . . . . . . . . . 165S. Cadavid-Arboleda, L.M. Ramirez-Arbelaez, E. Perez-Giraldo, S. Restrepo-Agudelo,S. Roldan-Vasco, J.C. Suarez-Escudero, G. Cantillo-Mackenzie, C.L. Bedoya-Londono,L. Martinez-Moreno, and A. Orozco-Duque

Analyzing Multiple Accelerometer Configurations to Detect Falls and Motion . . . . . . . . . . . . . . . . . . . . . . . . . . . 169J.D. López, C. Ocampo, A. Sucerquia, and J.F. Vargas-Bonilla

MC3C3-E1cell response to zirconium (Zr) implants with different surface characteristicby digital image processing analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173

M.R. Katunar, A. Bouchet, J. Ballarre, and J.I. Pastore

Cost Estimate Methodology in procurement processes of ME . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 177V.O. Fagundes, R. Zaniboni, and R. Garcia

Evaluation of methods based on conventional videographyfor detection of gait events . . . . . . . . . . . . . . . . . . . . . . 181A. Arcila Cano, D. Ewins, A. Shaheen, and P. Catalfamo Formento

Brain Functional Connectivity in Parkinson’s disease – EEG resting analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185J. Carmona, J. Suarez, and J. Ochoa

Modeling Transient Otoacoustic Emissions in children with hearing impairment . . . . . . . . . . . . . . . . . . . . . . . . . . 189Y. Torné-Cabrera, L.M. Alvero, and E. Martínez-Montes

IoT Protocol Model on Healthcare Monitoring . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 193Edward Guillén, Jeisson Sánchez, and Leonardo Ramírez López

Force Plate Calibration and Setup for Assessments of Human Balance. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 197I. Ghersi, C.F. Castro Arenas, P.D. Borsoi, and M.T. Miralles

Contents LV

Medical Device by Health Care Facility Interoperability in Alarm Management . . . . . . . . . . . . . . . . . . . . . . . . . . 201J. Loureiro and R. Garcia

Characterization Framework for Ex-combatants Based on EEG and Behavioral Features . . . . . . . . . . . . . . . . . . . . 205Andrés Quintero-Zea, Lina M. Sepúlveda-Cano, Mónica Rodríguez Calvache, Sandra Trujillo Orrego,Natalia Trujillo Orrego, and José D. López

Auditory Brainstem Responses with AEP_AUDIX System Using an Optimized Broadband Chirp Stimulus . . . . . . . 209L.M. Alvero, J.A. Gaya, C. Miret, E. Velarde, A. Torres, E. Eimil, Y. Torne, and E. Martinez

Protein Network Related to Unfavorable Prognosis in Acute Myeloid Leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . 213L.F. Restrepo and S. Röthlisberger

Green synthesis of silver nanoparticles using green coffee bean extract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 217Lukas Cardeño Calle and Martha Elena Londoño López

Surface Electromyographic Characterization of Five Orofacial Ideomotor Praxis in 20 Healthy Individuals. . . . . . . . 221G. Cantillo-Mackenzie, L. Martinez-Moreno, C.L. Bedoya-Londoño, E. Perez-Giraldo, L.M. Ramirez-Arbelaez,S. Cadavid-Arboleda, S. Restrepo-Agudelo, S. Roldan-Vasco, A. Orozco-Duque, and J.C. Suarez-Escudero

New technique for determining age of coastal skates from Argentinian sea by digital image processing analysis:A preliminary study. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225

P.A. Cristini, J.I. Pastore, S.A. Barbini, J. Ballarre, D. Sabadín, and A. Bouchet

Electrodes based on PPy polymer for electrocardiography and impedance plethysmography . . . . . . . . . . . . . . . . . . 229O. Teran-Jiménez, D. Hernández-Rivera, and E. Suaste-Gómez

Gesture Recognition and Machine Learning Applied to Sign Language Translation . . . . . . . . . . . . . . . . . . . . . . . . 233Luis A. Estrada Jiménez, Marco E. Benalcázar, and Nelson Sotomayor

An IoT Approach to an ECG Online Monitor System in an Android Application . . . . . . . . . . . . . . . . . . . . . . . . . 237F.M. Machado, E.G. Bertogna, and M.A. Sovierzoski

Noninvasive approach to estimate ventilatory mechanics in spontaneous breathing with different PEEPand pressure support values: validation with mechanical simulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 241

I.C. Muñoz and A.M. Hernández

Characterization of silver nanoparticles for potential use as antimicrobial agent . . . . . . . . . . . . . . . . . . . . . . . . . . . 245J. Zapata-Giraldo, P. Mena, B. Galeano, N. Escobar, M. Mejía, I.C. Ortiz, D. Cuesta,L.E. Botero, and L.M. Hoyos-Palacio

Learning Tool for Mechanical Ventilation during Spontaneous Breathing Test on Patients Intoxicatedwith Pesticides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 248

M.B. Salazar Sánchez, A.M. Hernández Valdivieso, A.F. Botero Ospina, and C.C. Cortés Daza

A Comprehensive System for Healthcare Technology Management HTM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 252L. Vilcahuaman, M. Cordova, J. Kalafatovich, and R. Rivas

Development and Evaluation of a Method for Fall Detection Based on a Wrist-Located Device . . . . . . . . . . . . . . . 256T. de Quadros, A.E. Lazzaretti, and F.K. Schneider

Extending the horizon of biomedical engineering to help other species . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 260A.M. Gonzalez-Vargas

Platonic Tensegrities: dynamic aspects and characterization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 264C. Castro Arenas, I. Ghersi, P.D. Borsoi, and M. Miralles

LVI Contents

Wiimote-based Infrared System for Instrumental Tracking in Minimally Invasive Spine Procedures for Training . . . . 268M. Domínguez, D. Lorias, and R. Martínez

Real-Time processing of DVI signals on a FPGA as a Telemedicine modular solution. . . . . . . . . . . . . . . . . . . . . . 272G.F. Manotas, L.A. Rodríguez, and J.M. Velandia

Construction of arterial networks considering the Fahraeus-Lindqvist effect . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 277P.F. Brito, L.D.M. Meneses, B.M. Rocha, R.W. Santos, and R.A.B. Queiroz

Optical microscopy and autofluorescence recognition of Toxoplasma gondii and Cryptosporidium parvum oocysts . . . 281Alejandra Alba, Laura Baker, Graciela Juez, and Andrés Ramírez

A human gait temporal parameters calculation algorithm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 285P.E. Caicedo-Rodríguez, C.F. Rengifo-Rodas, and L.E. Rodríguez-Cheu

Health Technology Management for Digital Medical Scales in Primary Healthcare . . . . . . . . . . . . . . . . . . . . . . . . 289F.S. Rosa and R. Garcia

Selective cytotoxicity of a novel compound based on Ruthenium II in a Gallbladder carcinoma cell line . . . . . . . . . 293Hernán Villota, Sebastian Pizarro, Francisco Gajardo, Álvaro Delgadillo, Fabián Cortés-Mancera,and Giuliano Bernal

Apoptosis induced by a novel Ruthenium II complex in a Gallbladder carcinoma cell line . . . . . . . . . . . . . . . . . . . 297Hernán Villota, Sebastian Pizarro, Francisco Gajardo, Álvaro Delgadillo, Fabián Cortés-Mancera,and Giuliano Bernal

Optimization of spectral analysis of electrophysiological recordings of the subthalamic nucleus in Parkinson’sdisease: A retrospective study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 300

S.E. Valderrama-Hincapié, A.M. Hernández, F. Sánchez, S. Roldán-Vasco, A.L. López-Ríos,and W.D. Hutchison

Influence of the Immune System on the Biological Dynamics of the Interstitial Fluid Pressure . . . . . . . . . . . . . . . . 304R.F. Reis, R.W. dos Santos, and M. Lobosco

Comparing Myocardium Perfusion Data Acquired by a MRI-Phantom and a Mathematical Model . . . . . . . . . . . . . 308J.R. Alves, R.A.B. de Queiroz, and R.W. dos Santos

Color morphological reconstruction as a segmentation tool for microscope cell images . . . . . . . . . . . . . . . . . . . . . 312J.I. Pastore, M. Brun, A. Bouchet, and V.L. Ballarin

Virtual environment as complementary tool to learning of the Imaginology dental care . . . . . . . . . . . . . . . . . . . . . 316P.B. Neto, F.D.L. Abreu, and S.C.M. Rodrigues

Ergonomic and Biomechanical Evaluation of the use of Computers, Tablets and Smart Phones by Children.A Pilot Study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 320

Holman Ospina-Mateus, Benilda Niño-Prada, Keyla Tilbe-Ayola, and Sonia Contreras-Ortiz

Cardiovagal Reflex Blood Pressure Set Point Determination by Time Domain Analysis . . . . . . . . . . . . . . . . . . . . . 325Juan Carlos Perfetto and G.A. Ruiz

Experimental Study of Apatite Layer Formation on Chitosan/Bioactive Glass Scaffolds for Bone TissueRegeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 329

L.A. Quintero, D.O. Grajales, and D.M. Escobar

Contents LVII

A Simple Physical Model of Human Gait Using Principles of Kinematics and BTS GAITLAB . . . . . . . . . . . . . . . 333C.A. Collazos, H.E. Castellanos, J.A. Cardona, J.C. Lozano, A. Gutiérrez, and M.A. Riveros

Glu4Pred: A computational tool for design and testing of insulin therapies for patients with type 1 diabetes basedon interval simulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337

M. García-Jaramillo, J.S. Delgado, and F. León-Vargas

Tribological properties study of lubricants for possible nanoclays reinforced biomedical applications . . . . . . . . . . . . 341J. Pardo Bernal, L. Peña Parás, and R. Tamayo Ramirez

Robotic kinematics applied to human biomechanics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345J.F. Archila-Diaz, I.L. Argote-Pedraza, R. Bortholin, R. Rubin, J.N. Archila-Diaz, and M.L. Tronco

SAFER: A Context-Aware Ubiquitous Assistance Platform for Elderly Care. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349J.F. Bravo-Torres, H.S. Redrován-Parra, A.F. Soto-Sarango, J.A. Andrade-Padilla, E.F. Ordoñez-Morales,M. López-Nores, and Y. Blanco-Fernández

Time-course reconstruction of neural activity for multiples simultaneous sources. . . . . . . . . . . . . . . . . . . . . . . . . . 353P.A. Munõz-Gutiérrez and E. Giraldo

Biomedical IoT Device for Self-Monitoring Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357Tatiana Huertas and Diego Mendez

Physical and Chemical Emulation of a Cornea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 361R. Jaramillo Diaz, H. Dávila Torres, A.V. Molina Mojica, and L.J. Martínez Guerrero

Development of an Equipment to Prepare Nanofibers for Tissue Engineering Since a Standpointof the Industrial Design . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 365

S.L. Rúa Jiménez, J.D. Villate Lagos, E.Y. Gómez-Pachón, Y. Torres Perez, and E. Muñoz Prieto

Acquisition of Lower Limb Joint Variables by an Inertial Card System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 369C. Ramos, C.A. Collazos, and A. Maldonado

Analysis of the Improvement on Textural Information in Human Iris Recognition . . . . . . . . . . . . . . . . . . . . . . . . . 373Eduardo Garea Llano, Mireya S. García-Vázquez, Luis M. Zamudio-Fuentes, Juan M. Colores Vargas,and Alejandro A. Ramírez-Acosta

Evaluation of computer vision based objective measures for complementary balance function descriptionand assessment in Multiple Sclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 377

Germán D. Sosa, Juanita Sánchez, Xiomary Bermúdez, Angélica Ramírez, and Hugo Franco

Biomedical computational reproducible research using Madagascar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 381Jorge E. Monsegny

Muscle strain field estimation using object tracking in high definition video sequences . . . . . . . . . . . . . . . . . . . . . 385M.A. Zamora, H. Franco, Q. Fang, S. Shefelbine, A. Taylor, and A. Ramirez-Martinez

Design and Construction of a Wearable Wireless Electrogoniometer for Joint Angle Measurements in Sports . . . . . . 389Isabela M. Mercado-Aguirre and Sonia H. Contreras-Ortiz

Improve Image Quality for Minimally Invasive Surgery Simulator Using Lenses and Image Processing. . . . . . . . . . 393Edgar M. Ramírez-Rodríguez, Daniel Lorias-Espinoza, and José Antonio Gutierrez-Gnecchi

Fabrication of piezoelectric PVDF/Graphene membranes by electrospinning for respiratory rateand temperature sensing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 397

D. Hernández-Rivera and E. Suaste-Gómez

LVIII Contents

Educative ECG Platform for Undergraduate Courses in BME . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 401Armando S. Hernández-Delgado, Arturo Vega-González, and Juan M. Gomez-González

Biomechanical analysis of a cranial Patient Specific Implant on the interface with the bone usingthe Finite Element Method . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 405

J.M. Díaz, O.A. González-Estrada, and C.I. López

Numerical simulation and fitting of tumor growth kinetics models using Python . . . . . . . . . . . . . . . . . . . . . . . . . . 409E.E. Ramirez Torres, L.E. Bergues Cabrales, R.E. Rivero Labrada, and J. Lambert Cause

A Low-Cost Methodology for Biomechanical Analysis of Martial Arts Using Videography and Accelerometers . . . . 413J.G. Vejar-Robles, A. Vega-Gonzalez, and R.P. Duarte-Zamorano

Identifying the needs in the integration of disciplines in the hospital infrastructure management in Colombia . . . . . . 417M. Madroñal Ortiz, B. Galeano Upegui, N. Escobar Mora, L. Cruz Parra, and I. Rios Cuartas

Approximations of Pupillary Shape in High-Definition Video-Oculography Registers . . . . . . . . . . . . . . . . . . . . . . 421R. Mora-Martínez and E. Suaste-Gómez

Motion Artifacts Recognition in Electrocardiographic Signals through Artificial Neural Networksand Support Vector Machines for Personalized Health Monitoring . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425

F.A. Castaño and A.M. Hernández

Thermographic comparative study between an acupuncture point and sham acupuncture for cervical pain . . . . . . . . 429D.V.Q. Moreira and P. Nohama

Iterative joint dynamic brain mapping and neural activity modeling from electroencephalographic signals . . . . . . . . 433E. Giraldo, P.A. Munõz-Gutiérrez, and G. Castellanos-Dominguez

Autoregressive Models of Electrocardiographic Signal Contaminated with Motion Artifacts: Benchmarkfor Biomedical Signal Processing Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 437

F.A. Castaño and A.M. Hernández

Feature selection for KNN classifier to improve accurate detection of subthalamic nucleus during deep brainstimulation surgery in Parkinson’s patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441

L. Schiaffino, A. Rosado Muñoz, J. Francés Villora, M. Bataller, A. Gutiérrez, I. Martínez Torres, V.Teruel-Martí, and J. Guerrero Martínez

Ensemble Kalman filter for state estimation of brain activity by considering a large scale nonlinear dynamicalmodel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 445

P.A. Munõz-Gutiérrez and E. Giraldo

A CT-based and mechanobiologic model for the simulation of rotation of tibia deformities during patient´simmobilization treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 449

R.A. González-Carbonell, A. Ortiz-Prado, V.H. Jacobo-Armendáriz, Y.A. Cisneros-Hidalgo,and L. Morales-Acosta

A Comparison between Solar Radiation and Skin Cancer in South Brazil. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 453P. Bertemes-Filho and F. Imai

Inhibition of Erythrocyte Hemolysis induced by H2O2 with Mangifera indica L. extract . . . . . . . . . . . . . . . . . . . . 457E. Pareja, Y. Salazar, S.S. Arango, M.E. Maldonado, J.G. Zuluaga, and S. Restrepo

DelphiCare 4.0: Web Biotelemetry System. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 461R.J. Díaz, R. Villalpando, J.C. Hinojo, G.E. Ramírez, and L.A. Retana

Contents LIX

Cardiorespiratory Interaction Using Nonlinear Data Processing Techniques in Patients Undergoing Test Tube T . . . . 465J.I. Trapero, C.J. Arizmendi, C.A. Forero, S.K. Lopez, and B.F. Giraldo

Incidence and risks associated with nasal injury in newborns undergoing non-invasive ventilationthrough the binasal prong. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 469

D.F. Camillo, F.S. Barros, T.D. Costa, and P. Nohama

Study of Medical Device Purchasing Cycles through Temporal Series Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . 473J.C. Guerrero, J.H. García, and A.M. Hernández

Creation of the Biomedical Systems Engineering undergraduate program, School of Engineering, UNAM.. . . . . . . . 477J.M. Dorador-Gonzalez, L. Báez-Rivas, L. Gonzalez-Gonzalez, and M. Guillen-Mandujano

Analysis of the respiratory flow signal for the diagnosis of patients with chronic heart failureusing artificial intelligence techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481

J.C. Rodríguez, C.J. Arizmendi, C.A. Forero, S.K. Lopez, and B.F. Giraldo

Sudden Cardiac Death Prediction Based On a Nonlinear Estimation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 485R. Urda Benitez and A. Orozco Duque

Mechanical Characterization of a Breast Phantom . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 489D.A. Triana, K.L. Cristiano, J.C. Gutiérrez, and D.A. Miranda

Theoretical study of the interaction between carbon nanotubes and the linoleic acid, an atherogenic polyunsaturatedfatty acid . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 492

Ana M. Torres, John Bustamante, Andrés M. Garay-Tapia, and Tapas Kar

VCG and ECG indexes for classification of patients with Myocardial Infarction . . . . . . . . . . . . . . . . . . . . . . . . . . 496R. Correa, P.D. Arini, L.S. Correa, and E. Laciar

Incorporation of Current Density Map Method in the Epilepsy Surgery Protocol . . . . . . . . . . . . . . . . . . . . . . . . . . 500A.R. García, J.P. Graffigna, and R. Otoya

Signal modes for design-oriented analysis of active sEMG spatial filter electrodes. . . . . . . . . . . . . . . . . . . . . . . . . 504F.N. Guerrero, P.A. García, and E.M. Spinelli

An Age-based Multiscale Mathematical Model of the Hepatitis C Virus Life-cycle During Infection and Therapy:Including Translation and Replication . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 508

B.M. Quintela, J.M. Conway, J.M. Hyman, R.F. Reis, R.W. dos Santos, M. Lobosco, and A.S. Perelson

Vibrotactile System for the Replication of Textures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 512M. Santís, D. Jaramillo, and V.Z. Pérez

Nonlinear estimators of human movement in biomechanical signals: Comparison between Extended Kalman Filterand Unscented Kalman Filter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 516

M. Callejas Cuervo, M.A. Vélez Guerrero, and A.C. Alarcón-Aldana

Voice Controlled Prosthetic Hand with Predefined Grasps and Movements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 520Juan Pablo Ángel-López and Nelson Arzola de la Peña

ICA and SVM Clustering Applied to Remove Ocular Artifacts from Electroencephalography . . . . . . . . . . . . . . . . . 524J. Pena-Rodriguez, D.A. Sierra, and C.A. Conde-Cotes

Diaphragmatic pacemaker prototype with wireless communication. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 528Jorge Reynolds, Jose Forero, and Maria Arango

LX Contents

Three Dimensional Reconstruction and Airflow Simulation in a Realistic Modelof the Human Respiratory Airways . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 533

A.E. Ruiz and J.K. Aristizábal

Heart Models in 3D Print . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 537Jorge Reynolds and Nasdly Diaz

Nonlinear measures characterize atrial fibrillatory dynamics generated using fractional diffusion . . . . . . . . . . . . . . . 541J.P. Ugarte, S.I. Duque, A. Orozco-Duque, C. Tobón, J. Bustamante, and H. Andrade-Caicedo

Construction of arterial networks considering a power law with exponent dependent on bifurcation level . . . . . . . . . 545L.D.M. Meneses, P.F. Brito, B.M. Rocha, R.W. Santos, and R.A.B. Queiroz

Leveraging Wireless Communications and Biomedical Devices to Support Prehospital Trauma Carein Cuenca, Ecuador . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 549

R.D. Contreras-Chacón, J.F. Bravo-Torres, and M.K. Huerta

Electronic Stethoscope with Wireless Communication to a Smart-phone, Including a Signal Filteringand Segmentation Algorithm of Digital Phonocardiography Signals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 553

Jorge Reynolds, José Forero, Juan Botero, Vivian Leguizamón, Luis Ramírez, and Carlos Lozano

Permanent Magnets to Enable Highly-Targeted Drug Delivery Applications:A Computational and Experimental Study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 557

M. Mercado-M, A.M. Hernandez, and J.C. Cruz

Analysis of the stability control of motors used in biomechanical prostheses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 561C. Alvarez Picaza, M.I. Pisarello, and J.E. Monzón

Atrial fibrillation detection through heart rate variability using a machine learning approachand Poincare plot features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 565

J.P. Sepulveda-Suescun, J. Murillo-Escobar, R.D. Urda-Benitez, D.A. Orrego-Metaute, and A. Orozco-Duque

Mathematical Modeling of Human Eye Affected by Increased Intraocular Pressure as a tool for the Preventionof Glaucoma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 569

Eduardo Pinos-Vélez, Rocio Alvarez-Cardenas, Sebastian Torres-Ríos, Carlos Luis Chacón,William Ipanaqué-Alama, and Luis Serpa-Andrade

Model Fitting and Simulation of the Respiratory Control System under Incremental Exercise and Altitudein Healthy Subjects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 573

C.A. Sarmiento, A.M. Hernández, and L.Y. Serna

Supporting Diabetic Patients with a Remote Patient Monitoring Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 577S. Zulj, G. Seketa, D. Dzaja, F. Sklebar, S. Drobnjak, L. Celic, and R. Magjarevic

Climbing/Descending Stairs Detection Using Inertial Sensors and Implementing PCA and a SVM Classifier . . . . . . 581R. Alvarez, E. Pulido, and D.A. Sierra

Assessment protocol of wrist flexion and extension to support processes in occupational healthusing Myo Armband . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 585

V. Montoya-Leal, A. Orozco-Duque, J.P. Ugarte, M.A. Portela, J.C. Franco, and V.Z. Perez

In vitro study of proliferation and cellularisation on electrospun membranes for vascular prosthesis. . . . . . . . . . . . . 589Y. Montoya, R.A. Valencia, I.C. Ortiz, L.M. Hoyos, and J. Bustamante

Contents LXI

Height Difference Effects Between the Standard and the Equipment Under Test in Calibration Processfor Sphygmomanometers in Colombia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 593

M.A. Castro-Leal and M.A. Castro-Cortés

Parametric Modeling of Kinetic-Kinematic Polycentric Mechanical Knee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 597A.M. Cárdenas, J. Uribe, and A.M. Hernández

Usability Evaluation for a Vital Signs Monitor Prototype . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 601L.E. Arenas, P.J. Bedoya, L. Correa, J.G. Barreneche, and A.M. Hernández

New insights into the scoring of respiratory events based on alternative sensors:A comparative effectiveness study. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 605

C.R. Dell’Aquila, L.S. Correa, R. Correa, G.E. Cañadas, and E. Laciar

Prediction of Critical Air Quality Events Using Support Vector Machines and Particle Swarm Optimization. . . . . . . 609J.C. Zapata-Hernandez, Y.K. Rojas-Idarraga, D.A. Orrego, and J. Murillo-Escobar

SIRUMED©, software for wheelchair selection. A preliminary report. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 613J. Letechipia and A. Arredondo

Upper-Limb Kinematics During Feeding and Drinking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 617Sergio Parra-Sánchez, Juan Manuel Gómez-González, A. Iraís Quintero-Ortega, Laura E. Castellano,Birzabith Mendoza-Novelo, José Jorge Delgado-García, Mayra Cuéllar-Cruz, and Arturo Vega-González

The Output Circuit of a Biphasic Constant Current Electrical Stimulator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 621R.R. Nogueira, D.C. Souza, J.C. Palma, G.N. Nogueira-Neto, and P. Nohama

Facial Movements Detection Using Neural Networks and Mpeg-7 Descriptors Applied to Alternativeand Augmentative Communication Systems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 626

Alexandre Felippeto Henzen and Percy Nohama

Main Effects of Energy Drinks on Mood, Reaction Time and Brain Regions . . . . . . . . . . . . . . . . . . . . . . . . . . . . 630C. Martínez-Torres, M. Calvillo, C. Romero-Rebollar, D. Martínez-Cancino, M. Flores-Leal,and L. Jiménez-Angeles

Design of a Validation Protocol for Medical Technology According to Current Standards . . . . . . . . . . . . . . . . . . . 634J. Acevedo, N. Saldarriaga, J.S. Orozco, and J.H. García

Analysis of a Nurse Call System Implementation using a Wireless Sensors Network . . . . . . . . . . . . . . . . . . . . . . . 638R.A. Zapatán, E.E. Armijos, L. Serpa-Andrade, and Eduardo Pinos

Multichannel Planar Microelectrode Platform for Recording Extracellular Field Potentials . . . . . . . . . . . . . . . . . . . 642J.C. Franco, M.A. Portela, and H. Andrade-Caicedo

Modeling and simulation of ciprofloxacin pharmacokinetics: electric circuits approach. . . . . . . . . . . . . . . . . . . . . . 646J.D. Otálvaro, A.F. Zuluaga, and A.M. Hernández

Gait Kinematics of Load Carriage in Healthy College Students . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 650Fátima G. Tapia-Rodríguez, Daniela M. Castro, Favia P. Aviles H., J. Daniel Moreno-González,L. Fernando Andrade-Heredia, and Arturo Vega-González

An approach to emotion recognition in single-channel EEG signals using Stationary Wavelet Transform . . . . . . . . . 654A. Gómez, L. Quintero, N. López, J. Castro, L. Villa, and G. Mejía

Processing of thermal images oriented to the automatic analysis of hand thermoregulation . . . . . . . . . . . . . . . . . . . 658N. Zapata-Osorio, S. Orrego-Serna, L. Ramirez-Arbelaez, A. Castro-Ospina, and H. Fandiño-Toro

LXII Contents

Assessment of Ankle Movements Through a Game-Based Sphere: Proof of Concept . . . . . . . . . . . . . . . . . . . . . . . 662Alan Meana, David Negrete-Rojas, Rafael A. Nava-Gomez, Jose A. Ruiz-Diaz, Arturo Vega-Gonzalez,and Juan M. Gomez-Gonzalez

Analysis of the alignment angles and flexion angle in women with patellofemoral pain syndrome. . . . . . . . . . . . . . 666N.F. Diaz-Martinez, J.D. Pulgarin-Giraldo, L.E. Vinasco-Isaza, and W. Agredo

Managing Heterogeneous Medical Data: Learning from Experiences in Telemedicine . . . . . . . . . . . . . . . . . . . . . . 670J.C. Vanegas-Serna, J.J. Perez, and H. Andrade-Caicedo

Fibrosis evaluation of animal liver tissue by thermal conduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 674N. Alemán-García, A. Pérez-García, J. Sánchez-Melecio, F. Silva-Aguilera, E. Gutiérrez-Herrera,M.R. Ortiz-Posadas, J. Hernández-Ruiz, D. Kershenobich, and C. Sánchez-Pérez

Clinical Evaluation of Inductive Spectrometer to detect Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 678C.A. González-Díaz, M.C. Uscanga-Carmona, L.M. Lozano-Trenado, J.L. Ortíz, J.A. González,and C.I. Guerrero-Robles

Kinematic Soccer Kick Analysis Using a Motion Capture System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 682Juan Pablo Ángel-López, Belarmino Segura-Giraldo, Luz Dary Rodríguez-Sotelo,and Karol Bibiana García-Solano

Measurement of the strength of upper limbs in cervical injury users to design a propulsionwheelchair mechanism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 686

Norma Araceli Coral Hernández, Cuitláhuac Osornio Correa, María del Carmen Mercado Chaparro,Ana María Vásquez Gallego, Jorge Letechipia Moreno, and Andrés Torres Velásquez

Knee Joint Angle Monitoring System Based on Inertial Measurement Units for Human Gait Analysis . . . . . . . . . . . 690J.J. Castañeda, A.F. Ruiz-Olaya, C.N. Lara-Herrera, and F.Z. Roldán

Case Study: Audiometry and ECR profile time convergence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 694A.K. Quintana, Ma. P. Granados, and J.M. Cornejo

Computer models for ions under electric and magnetic fields: random walks and relocation of calciumin dendrites depends on timing and population type. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 698

J.F. Gomez-Molina, M. Corredor, A.A. Restrepo-Velasquez, and U.M. Ricoy

Structural and functional genomics analysis of methyltransferase genes and networks associate to understandantibiotic resistance inside the pangenome of Pseudomonas aeruginosa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 702

Diana Carolina Castaño, Jeanneth Mosquera-Redón, and Mauricio Corredor

Descriptive study of the courses offered in degree programs in Biomedical Engineering in Mexico . . . . . . . . . . . . . 706A.C. Pliego-Carrillo and E.G. Del Hierro-Gutierrez

Motor Imagery BCI System with Visual Feedback: Design and Preliminary Evaluation . . . . . . . . . . . . . . . . . . . . . 709L.C. Carrere and C.B. Tabernig

Linear and non-linear methods for analysis Center Pressure and its application in Diabetic Peripheral Neuropathy:A systematic review . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 713

D. Toloza and M. Zequera

Optimal design of a mechanism for children foot guiding. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 717P.A. Niño Suarez, F. Calderon-Romero, M.B. Calva-Yañez, E.A. Portilla-Flores, and O.A. Aviles-Sánchez

Contents LXIII

Thematic profile of the e-health field, based on mainstream scientific production . . . . . . . . . . . . . . . . . . . . . . . . . 721P. Romero, Y. Piedra, and M. Nyssen

Thermoregulation of the hand: assessment with infrared thermography. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 725L.C. Ospina-Restrepo, L.M. Herrera-Velasquez, C.J. Barrera-Causil, H.A. Fandiño-Toro,and L.M. Ramirez-Arbelaez

Exhaled Breath analysis of smokers and nonsmokers using sensors based ultrapure Organically ModifiedGold Nanoparticles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 729

O.E. Gualdrón, T.G. Welearegay, A.L. Jaimes, J.M. Cáceres, C.M. Durán, R. Ionescu, M. Maestre,and G. Pugliese

Synthesis and characterization of nanofibroin hydrogels from Colombian silkworm Bombyx Mori L. . . . . . . . . . . . . 732A. Zuluaga-Velez, R. Buitrago-Sierra, J.F. Santa, F.A. Tabares-Villa, E. Aguilar, and J.C. Sepúlveda-Arias

Human-Computer Interaction for Image Guided Surgery Systems using Physiological Signals:Application to Deep Brain Stimulation Surgery. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 737

D.A. Jimenez, J.B. Padilla, R. Arango, and H.F. Garcia

Programs in Biomedical Engineering Education: How to Improve it . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 741G. Avendaño and A. Rienzo

Video Tracking Analysis System for Forelimb Akinesia test in the Rat Parkinson model . . . . . . . . . . . . . . . . . . . . 745M.P. Bonaccorso Marinelli, M.J. Ledesma, F.E. Nieto Grimalt, and R.J. Cabrera

Rat spinal cord transection injury progression: an MRI study . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 749M. Flores-Leal, A. Morales-Guadarrama, H. Salgado-Ceballos, and E. Sacristán-Rock

Mobile Application: Assistance in Mathematics Basic Operations in Children with Learning Disabilities . . . . . . . . . 753F.D.L. Abreu, F.P. Silva, P.B. Neto, M.A.S. Bissaco, and S.C.M. Rodrigues

Dispersive Raman Analysis of Sacha Inchi Ozonated Oil . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 757H.C. Carvalho, D.A.B. Palacios, C.J. Lima, M.S. Melo, L. Silveira Jr, and R.A. Zângaro

Design of Chassis and Adjustable Elements to Support Posture for Pediatric Wheelchair . . . . . . . . . . . . . . . . . . . . 761Y. Torres-Pérez and C. Caballero-Reyes

Prosthetic Alignment and Biomechanical Parameters in Transtibial Amputees due Landmines. . . . . . . . . . . . . . . . . 765L.A. Luengas, G. Sanchez, K. Novoa,

Erratum to: Descriptive study of the courses offered in degree programs in Biomedical Engineering in Mexico . . . . E1A.C. Pliego-Carrillo and E.G. Del Hierro-Gutierrez,

Author Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 769

LXIV Contents