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    AUSTRALIANGUIDELINESFORTHE

    PREVENTIONANDCONTROLOF

    INFECTIONINHEALTHCARE

    CONSULTATIONDRAFT

    7JANUARY 2010

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    Contents

    2

    Contents

    Summaryofrecommendations.................................................................................................................... 7

    Introduction .................................................................................................................................................. 13

    PART A BASICS OF INFECTION CONTROL..................................... .................................................... .......................... 19

    A1 Infectioncontrolinthehealthcaresetting...................................................................................... 20

    A1.1 Risksofcontractingahealthcareassociatedinfection.......................................................... 20

    A1.2 Standardandtransmissionbasedprecautions...................................................................... 22

    A2 Overviewofriskmanagementininfectionpreventionandcontrol ......................................... 24

    A2.1 Riskmanagementbasics ....................................................... .................................................... 24

    A3 Apatientcentredapproach ........................................................... .................................................... 26

    A3.1 Patientcentredhealthcare ....................................................................................................... 26

    A3.2 Howdoespatientcentredcarerelatetoinfectioncontrol?.................................................. 26

    PART B STANDARD AND TRANSMISSION-BASED PRECA UTIONS.......... ............................................ ................. ........ 28B1 Standardprecautions.......................................................................................................................... 29

    B1.1 Handhygieneandcoughetiquette ......................................................................................... 30

    B1.2 Personalprotectiveequipment ................................................................................................ 36

    B1.3 Handlinganddisposingofsharps........................................................................................... 47

    B1.4 Routinemanagementofthephysicalenvironment .............................................................. 51

    B1.5 Processingofinstrumentsandequipment .................................................................. ........... 63

    B2 Transmissionbasedprecautions...................................................................................................... 69

    B2.1 Applicationof

    transmission

    based

    precautions .................................................................... 70

    B2.2 Contactprecautions .................................................. ............................................................ ..... 71

    B2.3 Dropletprecautions .................................................. ............................................................ ..... 74

    B2.4 Airborneprecautions................................................................................................................. 77

    B2.5 Puttingitintopractice ......................................................... ...................................................... 80

    B3 Managementofresistantorganismsandoutbreaksituations.................................................... 89

    B3.1 Managementofmultiresistantorganisms............................................................................. 90

    B3.2 Outbreakinvestigationandmanagement ..................................................................... ......... 99

    B3.3 Puttingit

    into

    practice ......................................................... .................................................... 106

    B4 applyingstandardandtransmissionbasedprecautionsduringprocedures......................... 107

    B4.1 Takingariskmanagementapproachtoprocedures........................................................... 108

    B4.2 Therapeuticdevices .............................................................. ................................................... 110

    B4.3 Surgicalprocedures ............................................................ ..................................................... 121

    B4.4 Puttingitintopractice ......................................................... .................................................... 125

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    PART C ORGANISATIONAL SUPPORT.......................... .................................................... .......................................... 126

    C1 Managementandclinicalgovernance .................................................. ......................................... 127

    C1.1 Clinicalgovernanceininfectioncontrol ...................................................................... ......... 127

    C1.2 Rolesandresponsibilities........................................................................................................ 129

    C1.3 Infectionpreventionandcontrolprogram .............................................................. ............. 131

    C1.4 Riskmanagement..................................................................................................................... 133

    C1.5 Takinganorganisationalsystemsapproachtoriskmanagement .................................... 134

    C2 Staffhealthandsafety...................................................................................................................... 136

    C2.1 Rolesandresponsibilities........................................................................................................ 136

    C2.2 Healthstatusscreeningandimmunisation.......................................................................... 137

    C2.3 Exclusionperiodsforhealthcareworkerswithacuteinfections....................................... 138

    C2.4 Healthcareworkerswithspecificcircumstances................................................................. 140

    C2.5 Exposureproneprocedures ................................................................................................... 141

    C2.6 Occupationalhazardsforhealthcareworkers ..................................................................... 142

    C3 Educationandtraining ........................................................... .......................................................... 145

    C3.1 Teachingfacilities..................................................................................................................... 145

    C3.2 Healthcarefacilities.................................................................................................................. 147

    C3.3 Educationstrategies................................................................................................................. 148

    C3.4 Exampleofeducationinpracticehandhygiene............................................................. 148

    C3.5 Complianceandaccreditation................................................................................................ 150

    C3.6 Patientengagement.................................................................................................................. 150

    C4 Healthcareassociatedinfectionsurveillance............................................................................... 152

    C4.1 RoleofsurveillanceinreducingHAI.................................................................................... 152

    C4.2 Typesofsurveillanceprograms............................................................................................. 153

    C4.3 Datacollectionandmanagement........................................................................................... 154

    C4.4 Outbreaksurveillance ............................................................................................................. 155

    C4.5 Diseasesurveillanceinofficebasedpractice ....................................................................... 155

    C4.6 Notifiablediseases .......................................................... ......................................................... 156

    C5 Antibioticstewardship..................................................................................................................... 157

    C5.1 Background............................................................................................................................... 157

    C5.2 Antibioticstewardshipprograms.......................................................................................... 158

    C5.3 Antibioticstewardshipsurveillancemethods...................................................................... 159

    C6 Influenceoffacilitydesignonhealthcareassociatedinfection ............................................... 161

    C6.1 Facilitydesignanditsimpactoninfectioncontrol.............................................................. 161

    C6.2 Mechanismsforinfluencinghealthcareassociatedinfectionthroughenvironmental

    design......................................................................................................................................... 162

    C6.3 Thebenefitsofsinglebedroomsforpatientisolation....................................................... 166

    C6.4 Constructionandrenovation................................................................................................. 167

    C6.5 Guidancedocuments............................................................................................................... 167

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    PART D STANDARDS, LEGISLATION A ND OTHER RESOURCES......................... ............................................ ............. 168

    D1 Generalinfectioncontrolresources........................................................................................ 169

    D2 Standardprecautions................................................................................................................ 170

    D3 Transmissionbasedprecautions ............................................................................................ 172

    D4 Devicemanagement ................................................................ ................................................. 173

    D5 Involvingpatientsintheircare ....................................................... ........................................ 174

    D6 Staffhealthandsafety ............................................................. ................................................. 175

    D7 Surveillance................................................................................................................................ 175

    D8 Facilitydesign............................................................................................................................ 176

    APPENDICES...................................................................................................................................................................177

    1 MembershipandTermsofreferenceoftheWorkingCommittee............................................. 178

    2 Processreport ....................................................... ........................................................... ..................... 180

    3 Exposureproneprocedures(EPP) .......................................................... .......................................... 189

    Glossary ............................................................... ........................................................... ............................. 194

    Abbreviationsandacronyms ....................................................... ............................................................ 200

    References.................................................................................................................................................... 202

    List of tables and figures

    Tab les

    Table1: Directoryofkeyinformationintheseguidelines ......................................................... ...................... 11

    Table2: Sourcesofevidencetosupportrecommendations............................................................................. 14Table3: NHMRCgradesofevidence.................................................................................................................. 16

    Table4: Keytotypesofinformationhighlightedintheguidelines................................................................ 17

    Table5: Topicsdiscussedintheguidelines........................................................................................................ 18

    TableA1.1: Howstandardprecautionsareimplemented...................................................................................... 22

    TableA1.2: Strategiesforimplementingtransmissionbasedprecautions .......................................................... 23

    TableA2.1: Riskanalysismatrix .......................................................... ............................................................... ....... 24

    TableB1.1: Stepsincoughetiquette.......................................................................................................................... 32

    TableB1.2: Useofalcoholbasedhandrub.............................................................................................................. 33

    TableB1.3: Usingsoap(includingantimicrobialsoap)andwater....................................................................... 33

    TableB1.4: Characteristicsofaprons/gowns ................................................................ ........................................... 37

    TableB1.5: Useoffaceandeyeprotectionaspartofstandardprecautions ....................................................... 38

    TableB1.6: Propertiesofdifferenttypesofmask.................................................................................................... 38

    TableB1.7: Selectionofglovetype............................................................................................................................ 41

    TableB1.8: PuttingonandremovingPPE............................................................................................................... 43

    Table

    B1.9: Reducing

    risks

    if

    a

    sharps

    injury

    is

    sustained ..................................................... ................................ 48TableB1.10:Characteristicsofdisinfectants.............................................................................................................. 52

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    TableB1.11:Managementofbloodorbodysubstancespills.................................................................................. 55

    TableB1.12 Recommendedroutinecleaningfrequenciesforclinical,patientandresidentareas.................... 56

    TableB1.13:Categoriesofitemsforpatientcare .......................................................... ............................................ 63

    TableB1.14:Generalcriteriaforreprocessingandstorageofequipmentandinstrumentsinhealthcaresettings...................................................................................................................................................... 66

    TableB2.1: Applicationofstandardandtransmissionbasedprecautions ......................................................... 81

    TableB2.2: Infectionswarrantingtransmissionbasedprecautionsbeforelaboratoryconfirmationofinfection ............................................................... .............................................................. ....................... 82

    TableB2.3: Typeanddurationofprecautionsforspecificinfectionsandconditions ....................................... 83

    TableB3.1 SuggestedapproachtoscreeningforMRSA....................................................................................... 93

    TableB3.2 SuggestedapproachtoscreeningforVREandMRGNdependentonlocalacquisitionrates..... 94

    TableB3.3: ExampleofasuccessfulstrategytopreventendemicityofMRSAinatertiaryhospitalinWA .96

    TableB3.4: ExampleofasuccessfulstrategytopreventendemicityofVREinatertiaryhospitalinWA.....96

    TableB3.5: Stepsinanoutbreakinvestigation...................................................................................................... 100

    TableB4.1: Levelofrisktopatientsfromdifferenttypesofprocedures........................................................... 108

    TableB4.2: Summaryofprocessesforappropriateuseofdevices..................................................................... 109

    TableB4.3: Keyconceptsinminimisingtheriskofinfectionrelatedtotheuseofinvasivedevices ............ 110

    TableB4.4: Summaryofprocessesforurethralcatheterinsertionandmaintenance ...................................... 112

    TableB4.5: CAUTImaintenancebundle ................................................... ........................................................... .. 113

    TableB4.6: RiskfactorsforIVDrelatedBSI .......................................................................................................... 114

    TableB4.7: Central

    venous

    catheter

    decision

    tree

    for

    adults............................................................................... 114

    TableB4.8: Summaryofprocessesforinsertionandmaintenanceofintravascularaccessdevices..............117

    TableB4.9: SummaryofstrategiesforpreventingVAP ...................................................................................... 119

    TableB4.10:VAPcarebundle......................................... ................................................................ ........................... 119

    TableB4.11:Summaryofprocessesforusingenteralfeedingtubes.................................................................... 120

    TableB4.12:Summaryofprocessespresurgicalprocedure ............................................................... .................. 122

    TableB4.13:Summaryofprocessesduringasurgicalprocedure ................................................................ ........ 123

    TableB4.14:Summaryofprocessesfollowingasurgicalprocedure ........................................................... ........ 124

    TableB4.15:Checklistofstandardprecautionsforprocedures............................................................................ 125

    TableC1: Recommendedvaccinationsforallhealthcareworkers .................................................................. 138

    TableC2: Staffexclusionperiodsforinfectiousillnesses.................................................................................. 139

    TableC3: Categoriesofexposureproneprocedures ...................................................... ................................... 141

    TableC4: Keyrequirementsofahospitalantibioticstewardshipprogram................................................... 158

    TableApp2.1:Clinicalquestionsforsystematicreview......................................................................................... 183

    Figures

    FigureA1.1:Riskmanagementflowchart ............................................................ ...................................................... 25

    FigureB1.1: Importanceofhandhygiene.................................................................................................................. 30

    FigureB1.2: The5momentsofhandhygiene........................................................................................................... 31

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    FigureB1.3: Processesforroutinecleaning ............................................................. .................................................. 51

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    SUMMARY OF RECOMMENDATIONS

    Theseguidelinesproviderecommendationsthatoutlinethecriticalaspectsofinfectionpreventionand

    control.TherecommendationsweredevelopedbytheInfectionControlSteeringCommittee1basedon

    systematicreviewsoftheliteratureundertakenspecificallyfortheseguidelinesoronguidelinesdeveloped

    byotheradvisorybodies.Theyshouldbereadinthecontextoftheevidencebase.Thisisdiscussedin

    SectionsB1,B2andB3,whichalsoincludeadviceonthepracticalapplicationoftherecommendations.The

    tablebelowlistsrecommendationsandthesectionoftheguidelinesinwhichtheyarediscussed.

    Rec om me nda tion Refer to:

    Standard preca utions

    Hand hygiene

    1 Routine hand hyg iene

    Hand hygiene must b e p erformed before and after every episode of pa tient c ontac t.

    This inc lud es:

    before touching a pa tient;

    before a proced ure;

    a fter a p roced ure or bod y fluid exposure risk;

    after touching a pa tient; and

    after touching a patients surroundings.

    Hand hygiene must a lso b e p erformed after rem ova l of gloves.

    Sec tion B1.1.2

    Page 30

    2 Choice of produc t for routine hand hygiene prac tices

    Alcoho l-ba sed hand rubs c onta ining at least 70% v/ v etha nol or equivalent should b e

    used for all routine hand hygiene p rac tices in the hea lthcare environm ent.

    Sec tion B1.1.3

    Page 32

    3 Choice of hand hygiene produc t when hands are visibly soiled

    If hand s a re visibly soiled, hand hygiene should b e performed using soa p a nd w ater.

    Sec tion B1.1.3

    Page 32

    Personal protective equipment

    4 Wearing of ap rons/ gow ns

    Ap rons or gow ns should b e a pp rop riate to the ta sk being und ertaken. They should b e

    wo rn for a single p roc ed ure or episod e of p atient c are and remo ved in the area

    where the ep isod e of ca re takes plac e.

    Sec tion B1.2.3

    Page 37

    5 Use of face and eye protection for proce dures

    A surgica l mask and go gg les must b e wo rn d uring p roc ed ures that ge nerate ae rosols,

    sp lashes or sp rays of b lood , bo dy fluids, sec retions or excretions into the fac e a nd eyes.

    Sec tion B1.2.4

    Page 38

    6 Wearing of gloves

    Glove s must b e wo rn as a single-use item for:

    each invasive procedure;

    c onta c t with sterile sites and no n-inta c t skin or muc ous me mb ranes; and

    any ac tivity tha t has been assessed as c arrying a risk of exposure to bloo d, bod y

    fluids, secretions and excretions.

    Gloves must be c hang ed be twee n pa tients and after every ep isod e of individua l

    pa tient ca re.

    Sec tion B1.2.5

    Page 40

    1 MembershipandtermsofreferenceoftheInfectionControlSteeringCommitteearegiveninAppendix1.

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    Rec om me nda tion Refer to:

    7 Sterile glo ves

    Sterile gloves must b e used for asep tic p roce dures and c onta c t w ith sterile sites.

    Sec tion B1.2.5

    Page 40

    Handling and disposal of sharps

    8 Safe hand ling of sharpsSharps must not b e p assed direc tly from hand to ha nd a nd ha ndling should b e kep t to

    a minimum .

    Need les must not be rec ap pe d, b ent, broken or d isassemb led a fter use.

    Sec tion B1.3.2Page 47

    9 Dispo sal of sharps

    The person who has used the sha rp must b e respo nsible fo r its imme dia te safe d isposal.

    Used sha rps must be disc arde d into a n ap prove d sha rps c onta iner a t the p oint-of-use.

    These m ust no t b e filled abo ve the m ark that indica tes the b in is three-qua rters full.

    Sec tion B1.3.3

    Page 48

    Routine environmental cleaning

    10 Routine c leaning of surfac es

    Clean freque ntly touc hed surfac es with de tergent solution a t least d aily, and whe n

    visibly soiled and after eve ry known c onta mination.

    Clea n ge neral surfac es and fittings whe n visibly soiled a nd imm ed iate ly a fter sp illage .

    Sec tion B1.4.2

    Page 51

    11 Cleaning of shared c linica l equipm ent

    Clean to uche d surfac es of shared c linic al eq uipment b etw een p atient uses, with

    detergent solution.

    Exce p tions to this should be justified by risk assessme nt.

    Sec tion B1.4.2

    Page 51

    12 Surfac e ba rriersUse surfac e b a rriers to p rote c t c linica l surfac es (inc luding equ ipment) tha t are:

    touc hed freque ntly with gloved hand s during the d elivery of pa tient ca re;

    likely to bec om e c onta minated with blood o r bo dy substanc es; or

    diffic ult to c lean (e.g. com pute r keyboa rds).

    Exce p tions to this should be justified by risk a ssessme nt.

    Sec tion B1.4.2Page 51

    13 Site de c ontam ination after spills of bloo d or other po tentially infec tious ma terials

    Spills of b lood or other po tentia lly infec tious ma terials should b e p romp tly c leaned as

    follows:

    wear utility gloves and other PPEap propriate to the ta sk;

    co nfine a nd c ontain spill, clean visible ma tter with dispo sab le ab sorbe nt ma terial

    and disc ard the used c leaning ma terials in the ap propriate wa ste c onta iner;

    clean the sp ill area w ith a c loth or pa per towels using dete rge nt solution.

    Use o f che mic al d isinfec ta nts suc h as sod ium hypo c hlorite should be based on

    assessme nt of risk of transmission of infe c tious ag ents from tha t sp ill.

    Sec tion B1.4.3

    Page 54

    Transmission- ba sed prec autions (see Sec tion B2)

    Contact precautions

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    Rec om me nda tion Refer to:

    14 Impleme ntation of c ontac t preca utions

    In ad dition to stand ard p rec autions, imp lement c onta c t prec autions in the presenc e

    of known o r suspe c ted infec tious ag ents that a re sprea d by d irec t or indirec t c onta c t

    with the pa tient or the p atient s environme nt.

    Sec tion B2.2.2

    Page 71

    15 Hand hygiene and pe rsonal protec tive equipm ent to prevent contac t transmission

    When working with pa tients who req uire c onta c t p rec autions:

    perform hand hygiene;

    put on g loves and gow n upon entry to the pa tient ca re a rea ;

    ensure that c lothing a nd skin do not c onta c t pote ntially c onta minated

    environme nta l surfac es; and

    remove gow n and gloves and perform ha nd hygiene before leaving the pa tient

    ca re area.

    Sec tion B2.2.3

    Page 71

    16 Hand hygiene when Clostridium difficileis suspe c ted o r known to be p resent

    To fa c ilitate the m ec hanica l rem ova l of spores, meticulously wash hands with soa p

    and wa ter and pa t d ry with single-use to wels.

    Use o f alc oho l-ba sed hand rubs alone ma y not b e sufficient to red uc e transmission of

    Clostridium difficile.

    Sec tion B2.2.3

    Page 71

    17 Patient c are equipm ent for pa tients on contac t preca utions

    Use p atient d ed ica ted eq uipment o r single-use non-critic al pa tient ca re eq uipment

    (e.g. b lood p ressure c uffs).

    If co mm on use of e quipm ent for multiple p atients is unavo idab le, c lean the e quipm ent

    and allow it to dry before use on a nother pa tient.

    Sec tion B2.2.3

    Page 72

    Droplet precautions

    18 Impleme ntation of droplet preca utions

    In a dd ition to stand ard p rec autions, imp lem ent d rop let prec autions for patients known

    or suspec ted to b e infec ted with ag ents transmitted by respirato ry drop lets (ie large-

    particle droplets >5 in size) that a re ge nerated by a p atient whe n co ughing,

    snee zing, ta lking, o r during suc tioning.

    Sec tion B2.3.2

    Page 74

    19 Persona l protec tive eq uipment to prevent drop let transmission

    When entering the pa tient ca re e nvironme nt, put on a surgic al ma sk.

    Sec tion B2.3.3

    Page 74

    20 Plac em ent of pa tients requiring drop let prec autions

    Place pa tients who req uire d rop let prec autions in a single-patient room when

    available.

    Sec tion B2.3.3

    Page 75

    Airborne precautions

    21 Impleme ntation of airborne preca utions

    In a dd ition to stand ard p rec autions, imp leme nt a irbo rne p rec autions for patients

    known or suspected to be infected with infectious agents transmitted person-to-person

    by the airborne route (ie airborne drop let nuc lei or pa rticles

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    Rec om me nda tion Refer to:

    23 Plac em ent of pa tients requiring airborne prec autions

    Pat ients on a irborne p reca utions should be pla c ed in nega tive p ressure roo ms or in a

    room from which the air do es not c irc ulate to o ther area s.

    Exce p tions to this should be justified by risk assessme nt.

    Sec tion B2.4.3

    Page 78

    Multid rug resistant o rganisms (see Sec tion B3)

    24 Imp leme ntation of co re strategies in the control of multi-resistant organisms (MRSA,

    MRGN, VRE)

    Imp lement transmission-ba sed prec autions for all pa tients c olonised or infec ted with a

    multi-resistant organism, including:

    putting on gloves and go wns be fore entering the pa tient ca re area;

    using pa tient ded ica ted or single-use non-c ritic al pa tient ca re e quipm ent

    (e.g. bloo d p ressure cuff, stethosc op e);

    using a single-pa tient roo m o r, if unava ilab le, coho rting p a tients with the sam e

    strain of m ulti-resista nt o rga nism in d esigna ted pa tient c are a reas; and

    ensuring c onsistent c leaning and d isinfec tion o f surfac es in close p roximity to the

    pa tient and tho se likely to be to uche d b y the pa tient and he althca re wo rkers.

    Sec tion B3.1.2

    Page 91

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    Finding information

    Theserecommendationsprovidethebasisforappropriateinfectioncontrolpracticeinthehealthcaresetting.

    PracticalguidanceontheirimplementationisgiveninPartBoftheseguidelines.Thefollowingtable

    providesadirectoryforthisguidance.

    Tab le 1: Directo ry of key informa tion in these guid elines

    WHEN YOU NEED TO KNOW READ PAGE

    Infec tion control ba sics

    What are standard precautions and how are they ap plied Basics p29

    How are transmission-based precautions app lied Basics p70

    How to help patients become involved in infection co ntrol Sec tion A3;

    Patient care tips also highlighted

    How to a pp ly the p roce ss of risk management Sec tion A2; Case studies pp35, 46, 50, 61,

    73, 75, 79, 98, 105

    Hand hygiene and c ough etiquette

    When to pe rform hand hygiene Basics p30; Contac t 71; Drop let p 74; MROs p90

    What hand hygiene products to use and how Basics pp 32 to 33; Ca se study p 35; MROs p90

    What to d o if there are cuts or ab rasions on y our hands Basics p33

    Aboutjewe llery or artificial fingernails and infec tion Basics p33

    How to ca re for your hand s Basics pp33 to 34

    How to p rac tice cough etiquette Basics p32

    Personal p rotective e quipm ent

    How to dec ide wha t PPE is need ed for a pa rtic ular situation Basics p36

    What PPE to we ar for routine clinical practice Stand ard p 71;

    What PPE to w ea r when there is a risk of co nta mina tion with

    blood, body fluids, secretions, or excretions

    Ap rons and go wns p37, fac e and e ye protection p38;

    gloves p40

    What PPE to w ea r when transmission-ba sed prec autions are

    implemented

    Contact p71; Droplet p74; Airbo rne p77;

    MROs p91; Summa ry p81

    When to wea r aprons and g owns Basics p37; Contac t 71

    When to wea r face and e ye protection Basics p38; Airbo rne 77

    When to wea r gloves Basicsp40; Contac t 71; Ca se study p 46

    What is the c orrec t proc ed ure for putting on and removing PPE Basics p43

    Hand ling and disposal of sharps

    How to avoid sharps injuries Basics p47 ; Ca se study p 50

    How to use need leless devic es Basics p49

    How to safe ly dispose of sha rps Basics p48

    What to do if a sharps injury is sustained Basics p48

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    Environmental cleaning

    What p roduc ts and proc esses to use for routine e nvironme ntal

    cleaning of surface s

    Basics p51, p56

    When to use disinfectants Basics p52; MROs p91

    How to m inimise c onta mination of c leaning implem ents and

    solutions

    Basics p53

    What products and processes to use when there is a spill of blood

    or body fluids

    Basics p54; Ca se study p 61

    Processing of instruments and equipment

    How to clean eq uipment and instruments Metho ds p63; Agents 64

    How to disinfect eq uipment and instruments Metho ds p64

    How to sterilise eq uipment and instruments Metho ds p65

    How to dec ide which proc essing is req uired Basics p63; 66; Ca se study p 68

    When there is a suspec ted o r co nfirmed infection

    What transmission-based precautions are required for a specific

    infec tious ag ent

    Summ ary p81, p83

    When to implement transmission-ba sed prec autions Gene ral p82; Contac t p71; Droplet p74; Airborne p77

    When to impleme nt the use of single-use or dedicated patient

    care equipment

    Contact p72; MROs p91

    What to consider when transporting pa tients Contac t p73; Droplet p75; Airborne p78

    Where to place p atients to avoid cross-contam ination Contac t p72; Droplet p75; Airbo rne p78;

    MROs p91; Outbreak p103

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    INTRODUCTION

    Effectiveinfectioncontrolpreventingthetransmissionofinfectiousorganismsandmanaginginfectionsif

    theyoccuriscentraltoprovidinghighqualityhealthcareforpatientsandasafeworkingenvironmentfor

    thosethatworkinhealthcaresettings.

    Healthca re-assoc iated infec tion is preventable

    Therearearound200,000healthcareassociatedinfections(HAIs)inAustralianacutehealthcarefacilities

    eachyear.ThismakesHAIsthemostcommoncomplicationaffectingpatientsinhospital.Aswellascausing

    unnecessarypainandsufferingforpatientsandtheirfamilies,theseadverseeventsprolonghospitalstays

    andarecostlytothehealthsystem.Theproblemdoesnotjustaffectpatientsandworkersinhospitals

    HAIscanoccurinanyhealthcaresetting,includingofficebasedpractices(e.g.generalpracticesurgeries,

    dentalclinics)andlongtermresidentialcarefacilities(seeGlossary).Anypersonworkinginorenteringa

    healthcarefacilityisatrisk.However,healthcareassociatedinfectionisapotentiallypreventableadverse

    eventratherthananunpredictablecomplication.ItispossibletosignificantlyreducetherateofHAIs

    througheffectiveinfectioncontrol.

    Infec tion control is eve rybod ys businessUnderstandingthemodesoftransmissionofinfectiousorganismsandknowinghowandwhentoapplythe

    basicprinciplesofinfectioncontroliscriticaltothesuccessofaninfectioncontrolprogram.This

    responsibilityappliestoeverybodyworkingandvisitingahealthcarefacility,includingadministrators,

    staff,patientsandcarers.

    SuccessfulapproachesforpreventingandreducingharmsarisingfromHAIsinvolveapplyingarisk

    managementframeworktomanagehumanandsystemfactorsassociatedwiththetransmissionof

    infectiousagents.Thisapproachensuresthatinfectiousagents,whethercommon(e.g.gastrointestinal

    viruses)orevolving(e.g.influenzaormultiresistantorganisms[MROs]),canbemanagedeffectively.

    Development of the guidelines

    AspartoftheAustralianCommissiononSafetyandQualityinHealthCares(ACSQHC)coordinated

    approachtothepreventionandcontrolofHAIs,theNationalHealthandMedicalResearchCouncil

    (NHMRC)wasaskedtodevelopguidelinestoprovidenationalguidanceforthecontrolofHAIsandalsoa

    foundationbywhichotherstrategiesaddressingthepriorityareaofHAIscanbeimplemented.

    TheNHMRCappointedanexpertgrouptoguidethedevelopmentprocess(SteeringCommittee

    membershipandtermsofreferencearegiveninAppendix1).Theguidelinesarebasedonthebestavailable

    evidence.Theybuildonexistingguidelinesandreviews,aswellassystematicreviewsoftheevidence.

    Aim

    Byassistinghealthcareworkerstoimprovethequalityofthecaretheydeliver,theseguidelinesaimto

    promote

    and

    facilitate

    the

    overall

    goal

    of

    infection

    control:

    Thecreationofsafehealthcareenvironmentsthroughtheimplementationofpracticesthatminimisetheriskof

    transmissionofinfectiousagents.

    Scope

    Thescopeoftheseguidelineswasestablishedatthestartoftheguidelinedevelopmentprocess,followinga

    periodofconsultationthatincludedforumsinvolvingawiderangeofstakeholders(seeAppendix2).

    Theguidelinesweredevelopedtoestablishanationallyacceptedapproachtoinfectioncontrol,focusingon

    coreprinciplesforinfectioncontrolandpriorityareasforaction.Theyprovideabasisforhealthcareworkers

    andhealthcarefacilitiestodevelopdetailedprotocolsandprocessesforinfectioncontrolthatapplytotheir

    specificsituation.

    Whiletheguidelinesfocusonacutecare,theriskapproachusedtoaddresstheprinciplesofinfectioncontrol

    meanstheyareapplicabletoawiderangeofhealthcaresettings,includingofficebasedpractice,residential

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    carefacilities,Aboriginalmedicalservices,homeandcommunitynursingandemergencyservices.Materials

    thatidentifyrelevantrisksandmakerecommendationsonorganisationalpoliciesandproceduresforother

    settingswillalsobedeveloped,basedontheprinciplesoutlinedintheseguidelines.Informationforpatients

    willalsobederivedfromtheseguidelines.

    Theguidelinesdonotincludedetailedinformationon:

    infectiousdiseases;

    pandemicplanning;

    thereprocessingofinstruments;

    occupationalhealthandsafety;

    hospitalhotelservicessuchasfoodservices,laundryservicesorwastedisposal;or

    engineering/healthfacilitydesign.

    TheguidelinesdonotduplicateinformationprovidedinexistingAustralianStandardsbutrefertospecific

    standardswhereverrelevant.

    Target audienc e

    Theguidelines

    are

    for

    use

    by

    all

    those

    working

    in

    healthcare

    this

    includes

    healthcare

    workers,

    managementandsupportstaff.

    Evidence base

    Theseguidelinesarebasedonthebestavailableevidenceandknowledgeofthepracticalitiesofclinical

    procedures.Theydrawfromotherworkinthisarea,includingthetwopreviousnationalinfectioncontrol

    guidelines,2internationalinfectioncontrolguidelines,systematicliteraturereviewsconductedtoinformthe

    developmentoftheseguidelines,workonHAIpreventionfromACSQHC,andAustralianStandards

    relevanttoinfectioncontrol.Australiandataareusedwhereveravailable.

    Tab le 2: Source s of evidenc e to supp ort reco mm endations

    Systematic ally de velope d international guidelines3

    World Health Organization

    Guidelines on ha nd hygiene in hea lth ca re (2009)

    United States Centers for Disea se C ontrol a nd Prevention

    Workbo ok for d esigning, imp lementing a nd eva luating a sharps injury p revention prog ram (2009)

    Guideline for isola tion p recautions: preventing tra nsmission of infec tious age nts in hea lthca re setting s (2007)

    Management of multidrug-resistant organisms in healthcare settings (2006)

    Guidelines for infection control in the dental setting (2003)

    Guidelines for environmental infection control in health-care facilities (2003)

    United Kingdom National Institute for Health and Clinical Excellence

    Surgica l site infect ion prevention a nd t rea tme nt of surgica l site infect ion (2008)

    Prevention of hea lthcare-assoc iated infection in prima ry and c omm unity care (2003)

    UK Dep artme nt of Health

    Epic 2: Nat ional evidenc e-b ased g uide lines for preve nting hea lthca re-assoc iated infec tions in NHS hospitals inEngla nd (2007)

    British Soc iety for Antimicrob ial Chem otherapy

    Guidelines for UK practice for the diagnosis and management of methicillin-resistant Stap hyloc oc cus aureus

    (MRSA) infec tions presenting in the c om mun ity

    Guidelines for the m ana ge ment of ho spital-ac quired pne umonia in the UK: Rep ort of the Working Party on

    Hospita l-Ac qu ired Pneum onia o f the British Soc iety for Antimic rob ial Che mo the rap y

    2 CDNA(2004)InfectionControlGuidelinesforthePreventionofTransmissionofInfectiousDiseaseintheHealthCareSetting.

    CommunicableDiseasesNetworkofAustralia.

    NHMRC(1996)InfectionControlintheHealthcareSetting.GuidelinesforthePreventionofTransmissionofInfectious

    Diseases.NationalHealthandMedicalresearchCouncil.Rescinded.3 TheseguidelineswereselectedbasedonanalysisusingtheAGREEtool,whichensuresthatguidelineshavebeen

    developedinarigorous,transparentandrobustmanner.ThisprocessisdiscussedindetailinAppendix2.

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    Canad ian Critica l Care Trials Group

    Com prehensive evidenc e-ba sed clinic al prac tice g uidelines for ventilator-assoc iated pne umonia: p revention

    (2008)

    Europe an Assoc iation o f Urology

    Europea n and Asian guidelines on ma nag em ent an d p revention of ca thete r-assoc iated urinary tract infec tions

    Sepa rate systema tic reviews of pub lished scientific and med ica l literature for areas of co ntroversy a nd c linica l

    variation4

    Alcohol products and other agents for hand hygiene

    Infec tion co ntrol mea sures relate d to the use o f intrava sc ular device s

    Positive p ressure room s in red uc ing risk for imm unoc om prom ised pa tients

    Sta ff exclusion p olicies relat ing to norov irus ga stroen teritis

    Persona l protec tive eq uipment in reduc ing the t ransmission of multi-resistant organ isms

    Isolation m ea sures for p atients infec ted with va nco myc in-resistant enteroc oc ci or multi-resistant Gram neg ative

    bacteria

    Education interventions for the prevention of HAIs

    Limitations of the grad ing proc ess as it applies to the prac tice of infec tion co ntrol

    TherecommendationsintheseguidelineswereformulatedbytheInfectionControlSteeringCommittee5

    throughaprocessofconsensus.Recommendationsaregivenwhenanactionisdeemedcriticaltopreventing

    ormanaginginfection.RecommendationsaregradedaccordingtotherevisedNHMRCgradingsfor

    assessingevidence,withtheadditionofgoodpracticepoints,whichoutlineactionsthatareessentialto

    infectionpreventionandcontrolbutwhereevidencegradescannotbeapplied.

    Inmanyareasofinfectioncontrol,theevidencemaybelimitedbytheinabilitytoconductcertainstudy

    designsthataredifficulttoimplementinrealpractice.Thishasimplicationsforthelevelofgradingthatis

    assignedtotherecommendations,sincegradingsystemswilltendtofavourstudydesignsthatare

    sometimesnotfeasibleorunethicaltoconductininfectioncontrolsettingssuchasrandomisedcontrolled

    trials.Forexample,itisunethicaltocomparetheincidenceofinfectionrelatedtosurgicalinstrumentsby

    allocatingonepatientgrouptohavesterilisedinstrumentsusedonthemandonepatientgrouptohavenon

    sterileinstruments

    used

    on

    them.

    This

    may

    result

    in

    alower

    grading

    due

    to

    the

    available

    evidence

    but

    sterilisationofsurgicalinstrumentsisuniversallydeemedcriticaltoinfectioncontrol.

    Giventhatthereislimitedevidenceavailabletosupportmanyroutinepracticesintendedtoreduceinfection

    risk,practiceisbasedondecisionsmadeonscientificprinciples.Someactivities,suchaspractisinghand

    hygienebetweenadministeringcaretosuccessivepatients,haveacrediblehistorytosupporttheirroutine

    applicationinpreventingcrossinfection.Others,suchassomeuniformandclothingrequirements,have

    moretodowiththeethosofqualitycareandworkplaceculturethanwithaprovenreductionofcross

    infection.

    Itisnotacceptabletodiscontinuepracticesforwhichthereisasolidscientificbasis,evenifthelevelof

    evidenceisnothigh.Rather,routinepracticesshouldcontinueunlessthereissufficientevidencetosupport

    alternativeprocedures.

    Continuing

    research

    is

    needed

    to

    keep

    evaluating

    practice,

    to

    identify

    evidence

    gaps

    andpromoteresearchintheseareas,andensurethatpoorpracticesdonotcontinue.

    4 Duetoapaucityofevidenceorlowqualityevidencesomesystematicreviewswerenotusedtodraftrecommendations.

    5 MembershipoftheInfectionControlSteeringCommitteeisgiveninAppendix1.

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    Tab le 3: NHMRC grad es of evid enc e

    Grade Description

    A Body of evidenc e c an b e trusted to guide p rac tice

    B Bod y of evidenc e c an b e trusted to guide prac tice in most situations

    C Bod y of evidenc e p rovide s some supp ort for reco mm end ation(s) but c are should b e ta ken in

    its ap plication

    D Body o f evidence is wea k and reco mmend ation must be ap plied with caution

    TheICGSteeringCommitteealsoassignedanadditionalgradereferredtoasgoodpracticepoints(GPPs):

    GPP Bod y of evidenc e is wea k or non-existent. Rec omm end ation for be st prac tice b ased on

    clinical experience and expert opinion

    Struc ture of the guidelines

    Theseguidelinesarebasedaroundthefollowingcoreprinciples:

    anunderstandingofthemodesoftransmissionofinfectiousagentsandanoverviewofriskmanagement;

    effectiveworkpracticesthatminimisetheriskofselectionandtransmissionofinfectiousagents;

    governancestructures

    that

    support

    the

    implementation,

    monitoring

    and

    reporting

    of

    infection

    control

    workpractices;and

    compliancewithlegislation,regulationsandstandardsrelevanttoinfectioncontrol.

    ThePartsofthedocumentarebasedonthesecoreprinciplesandareorganisedaccordingtothelikely

    readership.

    PartApresentsbackgroundinformationthatshouldbereadbyeveryoneworkinginhealthcare(for

    exampleasorientationoraspartofannualreview)thisincludesimportantbasicsofinfectioncontrol,

    suchasthemainmodesoftransmissionofinfectiousagentsandtheapplicationofriskmanagement

    principles.Thispartoftheguidelinesdoesnotincluderecommendations.

    PartBisspecifictothepracticeofhealthcareworkersandsupportstaff,andoutlineseffectivework

    practicesthatminimisetheriskofselectionortransmissionofinfectiousagents.RecommendationsaregiveninSectionsB1toB3.Eachsectionincludesadviceonputtingtherecommendationsintopracticeandarisk

    managementcasestudy.

    SectionB1describesstandardprecautionsusedatalltimestominimisetheriskoftransmissionof

    infectiousagents;

    SectionB2outlinestransmissionbasedprecautionstoguidestaffinthepresenceofsuspectedorknown

    infectiousagentsthatrepresentanincreasedriskoftransmission;

    SectionB3outlinesapproachestothemanagementofmultiresistantorganisms(MROs)oroutbreak

    situations;and

    SectionB4outlinesprocessesforriskidentificationandtheapplicationofstandardandtransmission

    basedprecautions

    for

    certain

    procedures.

    PartCdescribestheresponsibilitiesofmanagementofhealthcarefacilities,includinggovernance

    structuresthatsupporttheimplementation,monitoringandreportingofeffectiveworkpractices.The

    chaptersoutlinethemaincomponentsofasystemsapproachtofacilitywideinfectioncontrol,giving

    guidanceonmanagementandstaffresponsibilities,protectionofhealthcareworkers,requirementsfor

    educationandtrainingofallstaff,considerationsforfacilitydesignandrenovation,andotherimportant

    activitiessuchassurveillanceandantibioticstewardship.

    PartDprovidesexamplesofrelevantstandards,legislationandresources.

    Theappendicesprovideadditionalinformationontheguidelinedevelopmentprocess,andsometoolsto

    assistinapplyingtherecommendations.

    Keyinformationishighlightedintheguidelinesasfollows.

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    Tab le 4: Key to type s of informa tion highlighted in the guidelines

    Summaries provide key information from ea c h sec tion of the g uidelines

    Rec omm enda tions (Sec tions B1, B2 and B3) outline the c ritica l aspe c ts of infec tion p reve ntion a nd c ontrol

    Patient c are tips highlight pa tient c onsiderations in the a pp lic ation o f infec tion c ontrol principles

    Casestudiesillustratetheapplicationofriskmanagementprinciples(SectionsB1,B2andB3)andmeasuresto

    supportgoodpractice(PartC)

    Thefollowingtablesummarisesthekeytopicsdiscussedinthedocument.

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    PART A BASICS OF INFECTION CONTROL

    Hea lthca re-assoc iated infec tions (HAIs) ca n oc c ur in any hea lthca re setting . While the spec ific risks ma y

    differ, the b asic principles of infec tion c ontrol ap ply reg ardless of the setting .

    In orde r to p revent HAIs, it is impo rta nt to unde rsta nd ho w infec tions oc c ur in healthc a re sett ings and then

    institute wa ys to p revent the m. Risk manage me nt is integral to this ap p roa ch.

    If effec tively imp lemented , the two -tiered a pp roa c h of stand ard a nd transmission-ba sed prec autions

    rec om mend ed in these guidelines provides high-level protec tion to pa tients, hea lthc are w orkers and

    other pe op le in healthca re settings.

    Infec tion control is integral to c linica l c a re a nd the way in which it is provided . It is not a n ad d itiona l set of

    practices.

    Involving p a tients is essential to suc c essful c linica l ca re. This inc lude s ensuring tha t pa tients rights a re

    respe c ted at all times, that they a re involved in dec ision-ma king ab out the ir c are, and they a re suffic ientlyinformed to b e a b le to p articipa te in red uc ing the risk of transmission of infec tious ag ents.

    The informat ion presente d in this Pa rt is releva nt to e verybo dy emp loyed b y a hea lthca re fa c ility, including

    ma nag em ent, hea lthca re w orkers and supp ort servic e staff.

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    21

    otherfactorsthatincreasetheriskoftransmissionofinfection(e.g.undergoingsurgery,requiringan

    indwellingdevicesuchasacatheter,orremaininginhospitalforlengthyperiods).

    Inhealthcaresettings,themostcommonsusceptiblehostsarepatientsandhealthcareworkers:

    Patientsmaybeexposedtoinfectiousagentsfromthemselves(endogenousinfection)orfromother

    people,instrumentsandequipment,ortheenvironment(exogenousinfection).Thelevelofriskrelatesto

    thehealthcaresetting(specifically,thepresenceorabsenceofinfectiousagents),thetypeofhealthcare

    proceduresperformedandthesusceptibilityofthepatient.

    Healthcareworkersmaybeexposedtoinfectiousagentsfrominfectedorcolonisedpatients,instruments

    andequipment,ortheenvironment.Thelevelofriskrelatestothetypeofclinicalcontacthealthcare

    workershavewithpotentiallyinfectedorcolonisedpatientgroups,instrumentsorenvironments,andthe

    healthstatusofthehealthcareworker(e.g.immunisedorimmunocompromised).

    Inhealthcaresettings,themainmodesoftransmissionofinfectiousagentsarecontact(including

    bloodborne),dropletandairborne.Themodesoftransmissionvarybytypeoforganism.Insomecasesthe

    sameorganismmaybetransmittedbymorethanoneroute(e.g.norovirus,influenzaandrespiratory

    syncytialvirus[RSV]canbetransmittedbycontactanddropletroutes).

    A1.1.1 Routes of transmission

    Conta c t transmission

    Contactisthemostcommonmodeoftransmission,andusuallyinvolvestransmissionbyhandorviacontact

    withbloodorbodysubstances.Contactmaybedirectorindirect.

    Directtransmissionoccurswheninfectiousagentsaretransferredfromonepersontoanotherfor

    example,apatientsbloodenteringahealthcareworkersbodythroughanunprotectedcutintheskin.

    Indirecttransmissioninvolvesthetransferofaninfectiousagentthroughacontaminatedintermediate

    objectorpersonforexample,ahealthcareworkershandstransmittinginfectiousagentsaftertouching

    aninfectedbodysiteononepatientandnotperforminghandhygienebeforetouchinganotherpatient,or

    ahealthcareworkercomingintocontactwithfomites(e.g.bedding)orfaecesandthenwithapatient.

    Examplesof

    infectious

    agents

    transmitted

    by

    contact

    include

    multi

    resistant

    organisms

    (MROs),

    Clostridiumdifficile,norovirusandhighlycontagiousskininfections/infestations(e.g.impetigo,scabies).

    Drop let transmission

    Droplettransmissioncanoccurwhenaninfectedpersoncoughs,sneezesortalks,andduringcertain

    proceduressuchassuctioning.Dropletsareinfectiousparticleslargerthan5micronsinsize.Respiratory

    dropletstransmitinfectionwhentheytraveldirectlyfromtherespiratorytractoftheinfectedpersonto

    susceptiblemucosalsurfaces(nasal,conjunctivaeororal)ofanotherperson,generallyovershortdistances.

    Dropletdistributionislimitedbytheforceofexpulsionandgravityandisusually1metreorless.However,

    dropletscanalsobetransmittedindirectlytomucosalsurfaces(e.g.viahands).

    Examplesofinfectiousagentsthataretransmittedviadropletsincludeinfluenzavirusandmeningococcus.

    Airborne transmission

    Airbornedisseminationmayoccurviaaerosols(smallairbornedropletslessthan5insize)containing

    infectiousagentsthatremaininfectiveovertimeanddistance.Aerosolscanbegeneratedbycoughingand

    sneezingandcertainprocedures,particularlythosethatinducecoughing,canpromoteairborne

    transmission.Theseincludeproceduressuchasdiagnosticsputuminduction,bronchoscopy,airway

    suctioning,endotrachealintubation,positivepressureventilationviafacemaskandhighfrequency

    oscillatoryventilation.Aerosolscontaininginfectiousagentscanbedispersedoverlongdistancesbyair

    currents(e.g.ventilationorairconditioningsystems)andinhaledbysusceptibleindividualswhohavenot

    hadanycontactwiththeinfectiousperson.Thesesmallparticlescantransmitinfectionintosmallairwaysof

    therespiratorytract.

    Examplesofinfectiousagentsthataretransmittedviatheairbornerouteincludemeasles(rubeola)virus,

    varicellavirusandM.tuberculosis.

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    Other modes of transmission

    Transmissionofinfectioncanalsooccurviacommonsourcessuchascontaminatedfood,water,

    medications,devicesorequipment.

    A1.2 STANDARD AND TRANSMISSION-BASED PRECAUTIONS

    Successfulinfectioncontrolinvolvesimplementingworkpracticesthatpreventthetransmissionof

    infectiousagentsthroughatwotieredapproachincluding:

    routinelyapplyingbasicinfectioncontrolstrategiestominimiserisktobothpatientsandhealthcare

    workers,suchashandhygiene,personalprotectiveequipment,cleaningandappropriatehandlingand

    disposalofsharps(standardprecautions);and

    effectivelymanaginginfectiousagentswherestandardprecautionsmaynotbesufficientontheirown.

    Thesespecificinterventionscontrolinfectionbyinterruptingthemodeoftransmission(transmissionbased

    precautions;formerlyreferredtoasadditionalprecautions).

    Ifsuccessfullyimplemented,standardandtransmissionbasedprecautionspreventanytypeofinfectious

    agentfrombeingtransmitted.

    A1.2.1 Standard prec autions

    Allpeoplepotentiallyharbourinfectiousagents.Workpracticestoensureabasiclevelofinfectioncontrol,

    coveredbythetermstandardprecautions,areappliedtoeveryone,regardlessoftheirperceivedor

    confirmedinfectiousstatus.Implementingstandardprecautionsasafirstlineapproachtoinfectioncontrol

    inthehealthcareenvironmentminimisestheriskoftransmissionofinfectiousagentsfrompersontoperson,

    eveninhighrisksituations.

    Standardprecautionsareusedbyhealthcareworkerstopreventorreducethelikelihoodoftransmissionof

    infectiousagentsfromonepersonorplacetoanother,andtorenderandmaintainobjectsandareasasfree

    aspossiblefrominfectiousagents.

    GuidanceonhowtoimplementstandardprecautionsisgiveninSectionB1.

    Tab le A1.1: How stand ard prec autions are implem ented

    Personal hygiene practices, particularly hand hygiene and cough etiquette, aim to reduce the risk of c ross-transmission a nd

    c ross-infec tion o f infec tious agents (see Sec tion B1.1).

    The use of personal protective equipment, which may include gloves, gowns, plastic aprons, masks/face-shields and eye

    protec tion, aims to p revent expo sure of the hea lthcare wo rker to infectious ag ents (see Sec tion B1.2).

    Appropriate hand ling a nd d isposal of sharps assist in preventing transmission of bloo d -bo rne d isea ses to hea lthca re wo rkers

    (see Sec tion B1.3).

    Environmental controls, inc luding c leaning a nd sp ills ma na ge me nt, assist in preve nting t ransmission of infec tious ag ents from

    the e nvironment to p a tients (see Sec tion B1.4).

    Appropriate reproce ssing of reusable eq uipment a nd instruments, including appropriate use of disinfectants, aims to

    p revent p a tient-to -pa tient transmission of infec tious age nts (see Sec tion B1.5).

    The a pp ropriate use o f aseptic and sterile techniques prevents conta mination of wound s and other susc ep tible sites by

    infec tious agents (see Glossary).

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    A1.2.2 Transmission-ba sed prec autions

    Anyinfectioncontrolstrategyshouldbebasedontheuseofstandardprecautionsasaminimumlevelof

    control.Transmissionbasedprecautionsarerecommendedasextraworkpracticesinsituationswhere

    standardprecautionsalonemaybeinsufficienttopreventtransmission.Transmissionbasedprecautionsare

    alsousedintheeventofanoutbreak(e.g.gastroenteritis),toassistincontainingtheoutbreakand

    preventingfurtherinfection.

    Transmissionbasedprecautionsshouldbetailoredtotheparticularinfectiousagentinvolvedanditsmode

    oftransmission.Thismayinvolveacombinationofpractices.

    GuidanceonwhenandhowtoimplementtransmissionbasedprecautionsisgiveninSectionsB2andB3

    andAppendices3and4.

    Tab le A1.2: Strategies for implem enting transmission-b ased p reca utions

    Transmission-based prec autions may include one or any c om bination o f the following:

    alloca ting a single room to a n infected pa tient (isolation);

    plac ing pa tients c olonised or infec ted with the sam e infectious ag ent in a room tog ether (co horting);

    wearing specific personal protective equipment;

    providing dedica ted pa tient equipment;

    using d isinfecta nts effec tive a ga inst the spe cific infectious ag ent;

    providing a d edica ted to ilet;

    use o f spe cific air hand ling tec hniques; and

    restricting m ovem ent b oth o f pa tients and hea lthcare w orkers.

    Contact p recautions are used w hen there is known or suspe c ted risk of transmission of infec tious age nts by d irec t or indirect

    contac t (see Sec tion B2.2).

    Droplet prec autions are used for pa tients known o r suspe ct ed to b e infecte d w ith age nts transmitted by respiratory droplets

    (see Sec tion B2.3).

    Airborne precautions are used for pa tients known o r suspe c ted to b e infect ed with ag ents transmitted pe rson-to-pe rson b y

    the airbo rne route (see Sec tion B2.4).

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    A2 OVERVIEW OF RISK MANAGEMENT IN INFECTION PREVENTION AND CONTROL

    Summary

    Identifying and ana lysing risks assoc iated with health c a re is an integ ra l pa rt of suc cessful infec tion c ontrol.

    Ad op ting a risk ma nage me nt a pp roa c h a t a ll levels of the fac ility is nec essa ry. This task req uires the full

    supp ort of the fac ilitys ma nag eme nt as well as c oop eration betw een ma nag eme nt, hea lthca re wo rkersand support staff.

    A2.1 RISK MANAGEMENT BASICS

    Inthecontextoftheseguidelines,riskisdefinedasthepossibilityofcolonisationorinfectionofpatientsor

    healthcareworkersarisingfromactivitieswithinahealthcarefacility.Riskmanagementisthebasisfor

    preventingandreducingharmsarisingfromhealthcareassociatedinfection.Asuccessfulapproachtorisk

    managementoccursonmanylevelswithinahealthcarefacility:

    facilitywideforexampleprovidingsupportforeffectiveriskmanagementthroughanorganisational

    riskmanagementpolicy,stafftrainingandmonitoringandreporting;

    wardordepartmentbasedforexampleembeddingriskmanagementintoallpoliciessothatrisksare

    consideredineverysituation;

    individualforexampleconsideringtherisksinvolvedincarryingoutaspecificprocedureand

    questioningthenecessityoftheprocedureaspartofclinicaldecisionmaking,attendingeducation

    sessions(e.g.handhygieneormaskfittraining).

    TheAustralian/NewZealandStandardonRiskManagementAS/NZS4360:2004outlinesastepwise

    approachtoriskmanagementthatallowscontinuousqualityimprovementandinvolves:

    establishingcontextidentifyingthebasicparametersinwhichriskmustbemanaged(e.g.thetypeof

    healthfacility,theextentofandsupportforthefacilitysinfectioncontrolprogram);

    avoidingriskestablishingwhetherthereisariskandwhetherpotentialriskcanbeaverted(e.g.by

    questioningwhetheraprocedureisnecessary);

    identifyingrisksasystematicandcomprehensiveprocessthatensuresthatnopotentialriskisexcluded

    fromfurtheranalysisandtreatment(e.g.usingrootcauseanalysis);

    analysingrisksconsideringthesourcesofrisk,theirconsequences,thelikelihoodthatthose

    consequencesmayoccur,andfactorsthataffectconsequencesandlikelihood(e.g.existingcontrols)(see

    riskanalysismatrixbelow);

    evaluatingriskscomparingthelevelofriskfoundduringtheanalysisprocesswithpreviously

    establishedriskcriteria,resultinginaprioritisedlistofrisksforfurtheraction;and

    treatingrisksselectingandimplementingappropriatemanagementoptionsfordealingwithidentified

    risk(e.g.modifyingprocedures,protocolsorworkpractices;providingeducation;andmonitoring

    compliancewith

    infection

    control

    procedures).

    Table A2.1: Risk ana lysis matrix

    ConsequencesLikelihood

    Negligible Minor Mod erate Major Extrem e

    Rare Low Low Low Medium High

    Unlikely Low Med ium Med ium High Very high

    Possible Low Medium High Very high Very high

    Likely Med ium High Very high Very high Extrem e

    Almost certain Med ium Very high Very high Extrem e Extrem e

    Low risk Mana ge by routine p rocedures.

    Medium risk Manage by specific monitoring or audit procedures.

    High risk

    Very hig h risk

    This is serious and must be add ressed imme d iate ly.

    The ma gnitude o f the co nseq uenc es of an eve nt, should it occ ur, and the likelihood of that e vent

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    A2 Overview of risk mana ge ment in infec tion prevention and c ontrol

    25

    Extrem e risk oc curring, are a ssessed in the c ontext of the effe c tiveness of existing strate gies and c ont rols.

    Monitoringandreviewisanessentialcomponentoftheriskmanagementprocess.Thisensuresthat:

    newrisksareidentified;

    analysisofriskisverifiedagainstrealdata,ifpossible;and

    risk

    treatment

    is

    implemented

    effectively.

    Communicationandconsultationarealsokeyelementsofclinicalriskmanagement.Aninteractiveexchange

    ofinformationbetweenmanagement,healthcareworkers,patientsandotherstakeholdersprovidesthebasis

    forincreasedawarenessoftheimportanceofinfectionpreventionandcontrol,identificationofrisksbefore

    theyariseandpromptmanagementofrisksastheyoccur.

    Thefollowingflowchartoutlineskeyconsiderationsduringtheprocessofriskmanagementinthecontextof

    infectioncontrolinthehealthcaresetting.Casestudiesgivingexamplesofhowtousethisprocess,including

    relevantconsiderationsinspecificsituations,areincludedinPartB.

    Figure A1.1: Risk ma nage me nt flowc ha rt

    Avoid riskAre there alte rna tive proc esses

    or proce dures that wo uld

    eliminate the risk?

    If a risk c annot be eliminated then

    it must be ma nage d

    Identify risks

    What infec tious age nt is involved?

    How is it transmitted?

    Who is at risk (patient and/or healthcare

    worker)?

    Treat risks

    What will be do ne to a dd ress

    risk?

    Who ta kes responsibility?

    How will c hang e be m onitored

    and reviewed ?

    Analyse risks

    Why c an it happ en (ac tivities,

    proc esses)?

    How often could it happ en?

    What are likely consequences?

    Communicatea

    ndconsult

    Eva luate risks

    What ca n be done to reduce o r

    elimina te the risk?

    How c ould this be ap plied in this

    situa tion (sta ff, resource s)?

    Monit

    orandreview

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    Part A Basics of infec tion c ont rol

    26

    A3 A PATIENT-CENTRED APPROACH

    Summary

    A p atient-centred hea lth system is known to be assoc iated with safer a nd higher quality ca re.

    A two -way a pp roa c h tha t enc ourage s pa tient pa rticipation is essential to suc c essful infec tion p revention

    and co ntrol.

    A3.1 PATIENT-CENTRED HEALTH CARE

    Peoplereceivinghealthcareincreasinglyexpecttobegiveninformationabouttheirconditionandtreatment

    optionsandthisextendstotheirrightsandresponsibilitiesasusersofhealthcareservices.Althoughpatient

    satisfactionwithhealthservicesinAustraliaisgenerallyhigh,patientsexperiencesarenotalwaysvalued

    andtheirexpectationsarenotalwaysmet.Whilethisdoesnotnecessarilyleadtopooroutcomesforthe

    individualsconcerned,thebestpossibleoutcomesaremorelikelywherepatientcentredhealthcareisa

    priorityofthehealthcarefacilityandastrongandconsistenteffortismadetorespectpatientsrightsand

    expectations.

    TheACSQHChasdevelopedanAustralianCharterofHealthcareRights,6whichrecognisesthatpeople

    receivingcareandpeopleprovidingcareallhaveimportantpartstoplayinachievinghealthcarerights.The

    Charterallowspatients,families,carersandservicesprovidinghealthcaretoshareanunderstandingofthe

    rightsofpeoplereceivinghealthcare.TheCharterstipulatesthatallAustralianshavetherightto:

    accessservicesthataddresstheirhealthcareneeds;

    receivesafeandhighqualityhealthservices,providedwithprofessionalcare,skillandcompetence;

    receivecarethatshowsrespecttothemandtheirculture,beliefs,valuesandpersonalcharacteristics;

    receiveopen,timelyandappropriatecommunicationabouttheirhealthcareinawaytheycan

    understand;

    joininmakingdecisionsandchoicesabouttheircareandabouthealthserviceplanning; havetheirpersonalprivacyandpersonalhealthandotherinformationproperlyhandled;and

    commentonorcomplainabouttheircareandhavetheirconcernsdealtwithproperlyandpromptly.

    Patientcentredcarecannotjustbeaddedontousualcare.Therights,experiencesandviewsofpatients

    shouldbeatthecentreofthecareprocessanddrivethewayinwhichcareisdelivered.Inmosthealthcare

    facilities,asignificantculturechangeisnecessarytoembedpatientcentredcareprinciplesintothe

    philosophyandpracticesoftheorganisation.Healthcareworkersandorganisationsneedtoacknowledge

    andunderstandtheCharterofHealthcareRightsandworktoensurethatpatientsrightsareintegraltothe

    careprocess.

    A3.2 HOW DO ES PATIENT-CENTRED CARE RELATE TO INFECTION CONTROL?

    Infectioncontrolisultimatelyaboutpeople.Effectiveinfectioncontroliscentraltoprovidinghighquality,

    patientcentredhealthcare.

    Puttingpatientsatthecentreofinfectioncontrolandenablingthemtoparticipateinthecareprocessisnot

    justaboutexplainingtherisksoftreatments,butinvolvesconsideringpatientsneedsateverylevel.This

    rangesfromdesigningthefacilitytomaximisepatientcomfortandsafetytohavingarangeofprocessesto

    engagepatientsintheircareandlistenandactontheirfeedbackaswellasprovidingthepatientwith

    educationandsupportsothattheycanbeinvolvedinlookingafterthemselves.

    6 Availableat:http://www.safetyandquality.gov.au/internet/safety/publishing.nsf/Content/compubs_ACHR

    roles/$File/17537charter.pdf

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    A3 A pa tient-centred a pp roach

    27

    Tosupportatwowayapproachtoinfectionpreventionandcontrolandencouragethepatientparticipation

    requiredtopreventinfectionandminimisecrossinfection,itisimportantto:

    takepatientsperspectivesintoaccountwhendevelopingpoliciesandprograms;

    familiarisepatientswiththeinfectionpreventionandcontrolstrategiesthatareemployedinhealthcare

    facilitiestoprotectthem,thepeoplecaringforthemandthehealthcareenvironment,andproceduresfor

    dealingwithinfectioncontrolbreaches;

    discusswithpatientsthespecificrisksassociatedwiththeirmedicaland/orsurgicaltreatment;

    encouragepatientstodisclosetheirhealthorriskstatusifthereisapotentialriskorsourceofinfectionto

    healthcareworkersorotherswithinthehealthcarefacility;

    provideopportunitiesforpatientstoidentifyandcommunicaterisksandencouragethemtouse

    feedbackproceduresforanyconcernsthattheyhaveaboutinfectionpreventionandcontrolprocedures;

    provideeducationalmaterialsaboutinfectionpreventionandcontrolusingavarietyofmedia,including

    postersinwaitingrooms,printedmaterialandeducationalvideos;and

    informpatientsabouttheprotocolsforprotectingtheirprivacyandconfidentiality.

    Specificguidanceonprovidingpatientcentredcareishighlightedthroughouttheguidelines,intextboxes,

    inthePuttingitintopracticesectionattheendofeachchapterinPartB,andineachchapterofPartC.

    Resourcesonhealthcarerights,culturalcompetence,andlinkstotoolsthataimtoassistdeliveryofpatient

    centredcare,arelistedinPartD.

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    PART B STANDARD AND TRANSMISSION-BASED PRECAUTIONS

    The use of sta ndard p rec au tions is the primary strategy for minimising the transmission o f healthc a re-associated infections.

    Transmission-ba sed p rec au tions are used in ad d ition to sta ndard p reca utions, where the suspec ted or

    known presence of infectious agents represents an increased risk of transmission.

    The ap p lic at ion o f transmission-ba sed prec autions is pa rtic ularly imp ortan t in c onta ining multi-resistant

    organisms (MROs) and in outbreak m ana ge ment.

    Med ica l and denta l proced ures increa se the risk of transmission of infec tious ag ents. Effec tive wo rk

    prac tice s to m inimise risk of transmission of infec tion related to proc ed ures req uire c onsiderat ion of t he

    spe c ific situation, as we ll as app rop ria te use o f sta ndard and t ransmission-ba sed p rec autions.

    Ap prop riate use o f asep tic t ec hnique a lso low ers the risk of infec tion risk by m inimising the numb er of

    infec tious ag ents to whic h p atients are exposed . This c omp rises c lean te c hnique (stand ard prec autions

    such as hand hyg iene, rep roc essing of e quipm ent b etw een pa tients, environme ntal c leaning) as a

    minimum, as well as sterile technique to prevent infectious agents from entering a patients bloodstream

    (e.g . use o f sterile instrume nts, d ressing m a teria ls and g love s, skin ant isep sis, and c rea tion o f a sterile field

    within which to op erate).

    The informa tion p resente d in this Part is pa rticula rly releva nt t o hea lthca re wo rkers and suppo rt sta ff. It outlines

    effec tive w ork prac tice s tha t m inimise t he risk of transmission o f infec tious ag ents.

    In a pp lying stand ard a nd transmission-ba sed infec tion c ontrols as part of d ay-to-da y p rac tice, hea lthc are

    wo rkers should e nsure tha t their pa tients understand why c ertain prac tices are b eing und ertaken, and that

    these p rac tices are in plac e to protec t eve ryone from infection. In this wa y, patients c an ta ke pa rt inminimising risks and question aspects of their care if necessary.

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    B1.1 Hand hygiene

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    B1 STANDARD PRECAUTIONS

    Summary

    It is essentia l tha t stand ard prec autions a re ap plied a t a ll time s. This is be c ause:

    pe op le ma y be plac ed at risk of infec tion from others who c arry infec tious ag ents;

    pe op le ma y be infec tious be fore signs or sympto ms of d isea se a re rec og nised or dete c ted , or before

    labo rato ry tests are c onfirmed in time to c ontribute to c are;

    pe op le ma y be a t risk from infec tious ag ents present in the surrounding environment includ ing

    environmental surfaces or from equipment; and

    there ma y be an inc reased risk of transmission assoc iated w ith spec ific proc ed ures and p rac tice s.

    Sta ndard prec autions c onsist of the ap prop riate use o f four distinct interventions:

    hand hygiene and coug h etiquette;

    the use o f pe rsona l protec tive equipm ent;

    the sa fe use and disposa l of sha rps; and

    routine environme ntal c leaning.Hand hygiene p rac tice s are rec omm ended before and after every episode of pa tient c ontac t. Stand ard

    prec autions should b e used in the hand ling o f:

    blood (including dried blood);

    all other bo dy fluids, sec retions and e xcretions (exclud ing swe a t), reg ardless of w hethe r they c ontain

    visible bloo d ;

    non-intac t skin; and

    muc ous mem branes.

    Ap prop riate d ispo sa l of hazardous ma terials (i.e. waste a nd linen) is a further imp ortant a spec t of infec tion

    c ontrol. This is outside the sc op e o f these g uidelines and prac tice in these a rea s should ad here to releva nt

    Australian standards.

    Evidenc e supporting prac tice

    Themajorityoftherecommendationsinthissectionhavebeenadaptedfrom:7

    GraysonL,RussoP,RyanKetal(2009)HandHygieneAustraliaManual.AustralianCommissionforSafety

    andQualityinHealthcareandWorldHealthOrganization;

    UnitedStatesCentersforDiseaseControlandPrevention(CDC)GuidelineforIsolationPrecautions:

    PreventingTransmissionofInfectiousAgentsinHealthcareSettings(2007);

    Prattetal(2007)Epic2:NationalEvidenceBasedGuidelinesforPreventingHealthcareAssociatedInfectionsin

    NHSHospitalsinEngland;and

    WorldHealthOrganization(2009)GuidelinesonHandHygieneinHealth.

    Furtherreviewoftheevidenceelicitedgoodqualityevidenceontheuseofalcoholbasedhandrubsin

    reducingtransmissionofinfectiousagents.8

    7 TheseguidelineswereselectedbasedonanalysisusingtheAGREEtool,whichensuresthatguidelineshavebeendevelopedinarigorous,transparentandrobustmanner.ThisprocessisdiscussedindetailinAppendix2.

    8 ThereportofthisreviewisavailablefromtheNHMRCuponrequest.

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    B1.1 HAND HYGIENE AND COUGH ETIQUETTE

    B1.1.1 What are the risks?

    Anyinfectiousagenttransmittedbythecontactordropletroutecanpotentiallybetransmittedbytouch.

    Microorganismsareeitherpresentonthehandsmostofthetime(residentflora)oracquiredduring

    activitiessuchashealthcare(transientflora).Handscanalsobecomecontaminatedthroughcontactwith

    respiratorysecretions

    when

    coughing

    or

    sneezing.

    Contaminated

    hands

    can

    lead

    to

    cross

    transmission

    of

    infectiousagentsinnonoutbreaksituations(Prattetal2001;CDC2002;Prattetal2007)andcontributeto

    outbreaksinvolvingorganismssuchasmethicillinresistantStaphylococcusaureus(MRSA),vancomycin

    resistantenterococci(VRE)andmultiresistantGramnegative(MRGN)microorganisms,suchas

    Acinetobacterspp(Prattetal2001).

    Figure B1.1: Imp ortanc e of hand hygiene

    Theseimagesillustratethecriticalimportanceofhandhygieneincaringforpatients,includingthosenotknownto

    carryantibioticresistantorganisms.Animprintofahealthcareworkersunglovedhandwasobtainedafterroutine

    abdominalexaminationofapatientwithnohistoryofMRSAinfectionbutfoundonroutinesurveillancetohave

    MRSAcolonisation.TheresultantcultureshowsMRSAcolonies(imageonleft).Anotherhandimprintobtainedafter

    theworkershandhadbeencleanedwithalcoholbasedhandrubwasnegativeforMRSA(imageonright).

    Source: DonskeyCJ&EcksteinBC(2009)Imagesinclinicalmedicine.Thehandsgiveitaway.NEnglJMed360(3):e3.

    Improvedhandhygienepracticeshavebeenassociatedwith:

    sustaineddecreasesintheincidenceofinfectionscausedbyMRSAandVRE(Websteretal1994;Zafaret

    al1995;Maliketal1999;Larsonetal2000a;Pittetetal2000;Pittet&Boyce2001);

    reductionsinhealthcareassociatedinfectionsofupto45%inarangeofhealthcaresettings(Fendleretal

    2002;Pittetetal2000;Ryanetal2001);and

    greaterthan50%reductionintheratesofnosocomialdiseaseassociatedwithMRSAandothermulti

    resistantorganisms,after12years(Graysonetal2008;Johnsonetal2005).

    Handhygienepracticesalonearenotsufficienttopreventandcontrolinfectionandneedtobeusedaspart

    ofamultifactorialapproachtoinfectioncontrol.

    B1.1.2 When should hand hyg iene be pe rformed ?

    Handscanbecomecontaminatedwithinfectiousagentsthroughcontactwithapatient,patient

    surroundings,the

    environment,

    or

    other

    healthcare

    workers.

    Cross

    contamination

    can

    occur

    from

    one

    site

    to

    anotherinthesamepatient,betweenhealthcareworkerandpatient,betweenpatientorhealthcareworker

    andtheenvironment,orbetweenhealthcareworkers.Practicinghandhygienebeforeeveryepisodeofpatient

    http://content.nejm.org/content/vol360/issue3/images/large/12f1.jpeghttp://content.nejm.org/content/vol360/issue3/images/large/12f1.jpeg
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    31

    contact(includingbetweencaringfordifferentpatientsandbetweendifferentcareactivitiesforthesame

    patient)andafteranyactivityorcontactthatpotentiallyresultsinhandsbecomingcontaminated(including

    removalofgloves)reducestheriskofcrosscontamination.

    The 5 mo me nts of hand hyg iene

    The5momentsofhandhygienedevelopedbytheWorldHealthOrganizationandadoptedbyHand

    HygieneAustralia

    (Grayson

    et

    al

    2009):

    protectpatientsagainstacquiringinfectiousagentsfromthehandsofthehealthcareworker;

    helptoprotectpatientsfrominfectiousagents(includingtheirown)enteringtheirbodiesduring

    procedures;and

    protecthealthcareworkersandthehealthcaresurroundingsfromacquiringpatientsinfectiousagents.

    Figure B1.2: The 5 mom ents of ha nd hyg iene

    Note: Handhygieneisalsoperformedaftertheremovalofgloves.

    Source: Graysonetal2009.

    RECOMMENDATION

    1 Routine hand hyg iene Grade

    Hand hygiene must be p erformed b efore and afte r eve ry episod e of pa tient co ntac t. Thisincludes:

    before touching a pa tient;

    before a proced ure;

    after a p roc ed ure or bod y fluid expo sure risk;

    after touching a pa tient; and

    after touching a patients surroundings.

    Hand hyg iene is also p erformed afte r the remo va l of g loves.

    B

    Cough e tiquette

    Coveringsneezes

    and

    coughs

    prevents

    infected

    persons

    from

    dispersing

    respiratory

    secretions

    into

    the

    air.

    Practisinghandhygieneaftercontactwithrespiratorysecretionsandcontaminatedobjectsormaterialsisan

    essentialelementofcoughetiquette.

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    Coughetiquetteisparticularlyimportantforpatientsondropletprecautions(seeSectionB2.3).

    Tab le B1.1: Step s in c oug h etiq uette

    Anyone with signs and symptoms of a respiratory infection, regardless of the cause, should follow or be instructed to follow

    co ugh etiquette a s follows:

    Cove r the nose/ mo uth when c oug hing or sneezing

    Use tissues to c onta in respiratory sec retions

    Dispo se o f tissues in the nea rest waste rec ep ta c le a fter use

    If no tissues are a vailable, co ugh or sneeze into the inner elbow rather than the ha nd

    Practice hand hygiene after contact with respiratory secretions and contaminated objects/materials

    B1.1.3 What prod uc t should be used ?

    Recentsystematicreviewsandexistingguidelines(Boyce&Pittet2002;Picheansathian2004;Prattetal2007;

    CanadaStandardsandGuidelineCoreCommittee2008;Larmeretal2008;PIDAC2008;Graysonetal2009)

    andother

    available

    review

    articles

    (Pittet

    &

    Boyce

    2001;

    Rotter

    2004;

    Nicolay

    2006)

    agree

    that

    hand

    hygiene

    usingalcoholbasedhandrubsismoreeffectiveagainstthemajorityofcommoninfectiousagentsonhands

    thanhandhygienewithplainorantisepticsoapandwater.

    Alcoholbasedhandrubs(liquidorgel)areeasilyaccessibleatpointofcareandhave(Graysonetal2009):

    excellentantimicrobialactivityagainstGrampositiveandGramnegativevegetativebacteria,

    Mycobacteriumtuberculosisandawiderangeoffungi;

    generallygoodantimicrobialactivityagainstenvelopedviruses;

    lesserand/orvariableantimicrobialactivityagainstnonenvelopedviruses(suchasnorovirus);and

    noactivityagainstprotozoanoocystsandbacterialspores(suchasC.difficile)(seeSectionB2.2).

    Therangeofantimicrobialactivityinalcoholbasedhandrubsvarieswiththealcoholcompound(ethanol,

    isopropanolornpropanol)used.Alcoholbasedhandrubsthathave70%byvolume(v/v)ethanolor

    equivalenthavesignificantlygreaterantimicrobialactivityagainstcommoninfectiousagentsthanthose

    below70%v/vethanol(Picheansathian2004;CanadaStandardsandGuidelineCoreCommittee2008;

    PIDAC2008).Theadditionofalowconcentrationofchlorhexidinetoanalcoholbasedhandrubenhances

    residualactivity(Rotter2004;Graysonetal2009)buthasbeenassociatedwithskinsensitivity.

    Alcoholbasedhandrubsdonotremovedirtorotherorganicmaterial,andcontinuedusemayleadto

    productbuildupthatleavesaresidue,requiringhandhygienewithliquidsoapandwater.

    Plainsoapsactbymechanicalremovalofmicroorganismsandhavenoantimicrobialactivity.Theyare

    sufficientforgeneralsocialcontactandforcleansingofvisiblysoiledhands.Thereisatendencyfor

    antimicrobialsoapstobemoreeffectivethanplainsoaps,althoughtheevidencearoundthisisinconsistent.

    Antimicrobialsoapisassociatedwithskincareissuesanditisnotnecessaryforuseineverydayclinical

    practice(Prattetal2001;CDC2002;Prattetal2007.)

    RECOMMENDATIONS

    2 Choice of produc t for routine hand hygiene prac tices Grade

    Alcoho l-ba sed hand rubs conta ining at least 70% v/ v etha nol or eq uivalent should b e

    used for all routine hand hygiene p rac tices in the hea lthcare environme nt.B

    3 Choice of hand hygiene produc t when hands are visibly soiled

    If hand s a re visibly soiled, hand hyg iene should be performed using soa p a nd wa ter. B

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    33

    Tec hnique

    Effectivehandhygienereliesonappropriatetechniqueasmuchasonselectionofthecorrectproduct.Key

    factorsineffectivehandhygieneandmaintainingskinintegrityinclude(CDC2002):

    thedurationofhandhygienemeasures;

    theexposureofallsurfacesofhandsandwriststothepreparationused(Widmer&Dangel2004);

    theuseofvigorousrubbingtocreatefriction;and ensuringthathandsarecompletelydry.

    Tab le B1.2: Use of alco hol-b ased hand rub

    App ly the amo unt of alcohol-ba sed hand rub recom mend ed b y the manufac turer to dry hands.

    Rub ha nds vigorously tog ether so tha t the solution c om es into co ntac t with all surfac es of the hand , pa ying p articular

    atte ntion to the tips of the finge rs, the thumb s and the a reas be twe en the fingers.

    Continue rubbing until the solution ha s eva po rated and the ha nds are d ry.

    Tab le B1.3: Using soa p (includ ing antimic robial soap) and wa ter

    Wet hands under tepid running w ater and ap ply the reco mmend ed amo unt of liquid soap .

    Rub hand s vigorously toget her for a minimum of 15 sec ond s so tha t the solution c om es into c onta ct with a ll surfac es of

    the ha nd, pa ying p articular attention to the tips of the fingers, the thumb s and the a reas be twe en the finge rs.

    Rinse ha nds tho rough ly under running wa ter, then p a t d ry with single-use to we ls.

    B1.1.4 Other aspec ts of hand hyg iene

    Asintactskinisanaturaldefenceagainstinfection,cutsandabrasionsreducetheeffectivenessofhand

    hygienepractices.Breaksorlesionsoftheskinarepossiblesourcesofentryforinfectiousagents(Larson

    1996)andmayalsobeasourceofthem.Toreducetheriskofcrosstransmissionofinfectiousagents,cuts

    andabrasionsshouldbecoveredwithwaterproofdressings.

    Thetypeandlengthoffingernailscanhaveanimpactontheeffectivenessofhandhygiene(CDC2002;Lin

    etal2003).Artificialnailshavebeenassociatedwithhigherlevelsofinfectiousagents,especiallyGram

    negativebacilliandyeasts,thannaturalnails(Pottingeretal1989;Passaroetal1997;Focaetal2000;

    Hedderwicketal2000;Moolenaaretal2000;Parryetal2001;CDC2002;Guptaetal2004;Boszczowskietal

    2005).Fingernailsshouldthereforebekeptshortandcleanandartificialfingernailsshouldnotbeworn.

    Althoughthereislessevidenceconcerningtheimpactofjewelleryontheeffectivenessofhandhygiene,

    ringscaninterferewiththetechniqueusedtoperformhandhygieneresultinginhighertotalbacterialcounts

    (CDC2002).Handcontaminationwithinfectiousagentsisincreasedwithringwearing(CDC2002;Tricket

    al2003),althoughnostudieshaverelatedthispracticetohealthcareworkertopatienttransmission.

    Wearingofjewelleryinclinicalareasshouldthereforebelimitedtoaplainband(e.g.weddingring)andthis

    shouldbemovedaboutonthefingerduringhandhygienepractices.Inhighrisksettingssuchasoperating

    suites/roomsthewearingofanyjewellery,evenaplainband,isnotrecommended.

    B1.1.5 Hand care

    Themaintypeofskinreactionassociatedwithhandhygiene,irritantcontactdermatitis,includessymptoms

    suchasdryness,irritation,itchingandsometimescrackingandbleeding.Allergiccontactdermatitisisrare

    andrepresentsanallergy,whichmaybetosomeingredientinahandhygieneproduct.

    Generally,alcoholbasedhandrubscausesignificantlylessskindamagethanhandhygienewithplainor

    antisepticsoaps(Pittet&Boyce2001).

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