ias continues to poison the drinking water of tens of millions of people around the world
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iAs continues to poison the drinking water of tens of millions of people around the world. More than 2.3 million people in North Carolina use water from private, unregulated wells . Data from 2009. Sanders et al 2011. >63,000 wells over 10 yrs Max=800 ppb - PowerPoint PPT PresentationTRANSCRIPT
iAs continues to poison the drinking water of tens of millions of people around the world
>63,000 wells over 10 yrsMax=800 ppb1436 wells contaminated above 10 ppbHundreds exceeded 50 ppb
More than 2.3 million people in North Carolina use water from private, unregulated wells
Sanders et al 2011
Data from 2009
Sanders et al 2011
Data from 2009
75,000 people
More than 2.3 million people in North Carolina use water from private, unregulated wells
>63,000 wells over 10 yrsMax=800 ppb1436 wells contaminated above 10 ppbHundreds exceeded 50 ppb
Cytochrome c oxidase• The enzyme cytochrome c
oxidase or Complex IV) is a large transmembrane protein complex found in bacteria and the mitochondrion.
• The complex contains two hemes a cytochrome a and cytochrome a3, and two copper centers, the CuA and CuB centers
1
2
3
Cd and Zn transporters
Methylmercury and methionine
Monovalent, divalent
elemental
inorganic
Inhibits ability to make hemoglobin
Cr(VI) is generally considered 1,000 times more toxic than Cr(III) [EPA 1998; ATSDR 2000; Dayan and Paine 2001].
• The toxicity of chromium compounds depends on the oxidation state of the metal.
• Occupational exposure to chromium(VI) compounds has been associated with increased incidence of lung cancer.
• Chromium(III) is an essential nutrient that can be toxic in large doses.
