hygiene of pharmacy establishments. structure of pharmacy pharmacy pharmacy base control analytical...
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HYGIENE OF PHARMACYHYGIENE OF PHARMACY ESTABLISHMENTSESTABLISHMENTS
STRUCTURE OF PHARMACY
Pharmacy Pharmacy Base
Control
Analytical Laboratory
A pharmacy is establishment of health A pharmacy is establishment of health protection, which functions from permission protection, which functions from permission and under control public organs, the basic and under control public organs, the basic task of which is providing of population, task of which is providing of population, sanitary and prophylaxis, treatment and sanitary and prophylaxis, treatment and prophylaxis, sanatorium-resort, science and prophylaxis, sanatorium-resort, science and medical establishments of health medical establishments of health protection, enterprises, establishments and protection, enterprises, establishments and organizations by medications and wares of organizations by medications and wares of the medical setting.the medical setting.
A pharmacy on which the A pharmacy on which the administrative is fixed and administrative is fixed and organization and methodical organization and methodical guidance by the pharmacies of guidance by the pharmacies of district (cities) is named a central district (cities) is named a central district (city) pharmacy. district (city) pharmacy.
A pharmacy which is intended A pharmacy which is intended exceptionally for providing of one or exceptionally for providing of one or a few hospitals and other a few hospitals and other establishments of health protection establishments of health protection by medicines and articles of the by medicines and articles of the medical setting is named accordingly medical setting is named accordingly hospital or by a clinically pharmacy.hospital or by a clinically pharmacy.
The pharmacies of general type The pharmacies of general type are divided onare divided on
pharmacies which carry out realization of medicinal
preparations only.
pharmacies which carry out making of medical forms realization of medicinal
preparations
GENERAL GENERAL PLANPLAN
A site of area must not A site of area must not
exceed 15 % from a general exceed 15 % from a general
area. A large value gets to area. A large value gets to
planting of greenery of areaplanting of greenery of area
for diminishing of noise,for diminishing of noise,
dusted and gassed. dusted and gassed.
GENERAL PLANGENERAL PLAN
The area of planting of greenery The area of planting of greenery must make not less than 60 % from must make not less than 60 % from the area of all area. the area of all area.
INTER HOSPITAL of INTER HOSPITAL of PHARMACY PHARMACY
Between hospitals of pharmacy get Between hospitals of pharmacy get organized mainly in cities and organized mainly in cities and situated within the limits of city or on situated within the limits of city or on territory of treatment and territory of treatment and prophylaxis establishment, medical prophylaxis establishment, medical township.township.
PHARMACIES OF GENERAL TYPEPHARMACIES OF GENERAL TYPE
The pharmacies of general type
can situeted
on ground floors
multistory
enterprises and inhabited
houses
In cooperation with
establishments
in buildings
in separate small
buildings
public and inhabited houses
Between the apartments of aseptic Between the apartments of aseptic complex in accordance with the stages of complex in accordance with the stages of technological process there must be technological process there must be successive direct intercommunication: successive direct intercommunication: washing room aseptic complex – washing room aseptic complex – sterilization room tableware – assistant – sterilization room tableware – assistant – aseptic (for making of injection medical aseptic (for making of injection medical forms) – assistant asepticforms) – assistant aseptic
(for making of eye drops and medical (for making of eye drops and medical forms)forms)
PHARMACPHARMACYY OFOF GENERAL GENERAL TapeTape
Pharmacy booth. The apartment of Pharmacy booth. The apartment of pharmacy booth is equipped by pharmacy booth is equipped by shelving's, closets, refrigerator. shelving's, closets, refrigerator. Minimum room measure - 8 m2. Minimum room measure - 8 m2.
HYGIENICAL ESTIMATION HYGIENICAL ESTIMATION TECHNOLOGICAL PROCESSES TECHNOLOGICAL PROCESSES MAKING AND REALIZATION OF MAKING AND REALIZATION OF
MEDICATIONSMEDICATIONS
Providing of optimum microclimatic terms in the Providing of optimum microclimatic terms in the apartments of pharmacies is carried out by the apartments of pharmacies is carried out by the system of heating and effective general chance of system of heating and effective general chance of mixed ventilation.mixed ventilation.
The apartments of pharmacies are heated by the The apartments of pharmacies are heated by the system centralized aquatic (convection) and block system centralized aquatic (convection) and block X-ray (radiation) heating. Most optimum and X-ray (radiation) heating. Most optimum and hygienically justified is the block X-ray heating. It hygienically justified is the block X-ray heating. It is especially expedient for heating of aseptic is especially expedient for heating of aseptic block, assistant and rooms of pharmaceutics and block, assistant and rooms of pharmaceutics and -analytic, where-analytic, where
the high level of cleanness must the high level of cleanness must stick to.stick to.
MicroclimatMicroclimat
Relative humidity must make in Relative humidity must make in pharmacy apartments 40-60 %, rate of pharmacy apartments 40-60 %, rate of movement of air - 0,1-0,2 m/sec. movement of air - 0,1-0,2 m/sec.
A light coefficient (LC) is in an A light coefficient (LC) is in an assistant, to the room of assistant, to the room of pharmaciespharmacies -analytic, aseptic must be 1:4, in -analytic, aseptic must be 1:4, in other apartments of pharmacy scope other apartments of pharmacy scope 1:6-1:7.1:6-1:7.
Lighting
A coefficient of natural illumination A coefficient of natural illumination (CLK) is in an assistant, to the room (CLK) is in an assistant, to the room of of pharmaciespharmacies -analytic, aseptic -analytic, aseptic must be evened - 2 %, in other must be evened - 2 %, in other apartments of pharmacy - 1,5-0,5 %. apartments of pharmacy - 1,5-0,5 %.
The orientation of apartments of The orientation of apartments of pharmacy after the sides of the world pharmacy after the sides of the world plays a considerable role in providing plays a considerable role in providing of the insulation mode. Optimum for of the insulation mode. Optimum for the basic shop floors of pharmacy is the basic shop floors of pharmacy is a south and south-east orientation.a south and south-east orientation.
A coefficient of deepening is at one-A coefficient of deepening is at one-sided illumination - relation of depth sided illumination - relation of depth of apartment (distance is from a wall of apartment (distance is from a wall to opposite) to the height of to opposite) to the height of overhead edge of window must not overhead edge of window must not be anymore 2,0.be anymore 2,0.
MICROBAL MICROBAL CONTAMINATIONCONTAMINATION
Aseptic block, where injection solutions, Aseptic block, where injection solutions, eye drops, are made, what complete eye drops, are made, what complete sterility is needed for) must be sterility is needed for) must be equipped by mixed ventilation with equipped by mixed ventilation with advantage of wave of air (multi planes advantage of wave of air (multi planes of ventilation +4-2) of ventilation +4-2) to exclude the receipt to exclude the receipt of air from other apartments. Thus motion of of air from other apartments. Thus motion of currents of air takes place from aseptic in currents of air takes place from aseptic in adjoining to it apartments - sluice, and then in adjoining to it apartments - sluice, and then in a corridor. The windows of aseptic must be a corridor. The windows of aseptic must be densely closed, cracks tight hammered in. densely closed, cracks tight hammered in. Reveal air must pass through filters which Reveal air must pass through filters which catch dust and microorganisms.catch dust and microorganisms.
Material (compositions) sterile Material (compositions) sterile materials must be equipped by reveal materials must be equipped by reveal ventilation with multi planes of ventilation with multi planes of ventilation +3.ventilation +3.
USED for washing pharmaceutical APPARATUS
TECHNOLOGICAL MEASURESTECHNOLOGICAL MEASURES
APPARATUS FOR DESINFECTED of prescriptions
Proper production practice (GMP - Good manufacturing Proper production practice (GMP - Good manufacturing practice) – part of the system of providing of quality, practice) – part of the system of providing of quality,
which guarantees that medications are produced and which guarantees that medications are produced and controlled in accordance with the vault of obligatory controlled in accordance with the vault of obligatory
principles, norms and rules, and also registration and principles, norms and rules, and also registration and licensed normative document the requirements of which licensed normative document the requirements of which
fully represent set and predictable consumer need, in fully represent set and predictable consumer need, in particular, efficiency and safety of application of particular, efficiency and safety of application of
medications, their quality, identity and stability.medications, their quality, identity and stability.
Basic elements providing of Basic elements providing of parameters of medicationsparameters of medications
control of quality
system is Proper
production practice (GMP)
The reliable licensing
DocumentsDocuments
Categories and Categories and types of types of
specificationsspecifications
BasiBasiss of the of the factorsfactors productproduct
INDIVIDUAL FACILITIES OF INDIVIDUAL FACILITIES OF DEFENCEDEFENCE
In a number of cases, when it is impossible to In a number of cases, when it is impossible to reduce noise to the possible sizes, the use of reduce noise to the possible sizes, the use of individual facilities of defense is individual facilities of defense is recommended.recommended.
There can be a considerable selection of There can be a considerable selection of harmful matters at sampling, opening of harmful matters at sampling, opening of hatches of vehicles, unloading of components hatches of vehicles, unloading of components and other operations, that is why at and other operations, that is why at implementation of such operations it follows to implementation of such operations it follows to use individual facilities of defense (respirators, use individual facilities of defense (respirators, gauze bandages and others like that). gauze bandages and others like that).
Basic types of protective Basic types of protective glassesglasses 1-5 – dust-, 1-5 – dust-, pairspairs -, gaz -, gaz
protection; 6-10 – for protecting from mechanical damagesprotection; 6-10 – for protecting from mechanical damages
gas-mask gas-mask
Oxygen isolated gas-masks Oxygen isolated gas-masks ( and – Kip-5; bi – Rkr-2) ( and – Kip-5; bi – Rkr-2)
Individual facilities of defense of organs of Individual facilities of defense of organs of breathingbreathing (and is the (and is the
improved respirator of Shb-1 („Petal 200”), kind from outside; bi is improved respirator of Shb-1 („Petal 200”), kind from outside; bi is a kind from a middle; in is the put on respirator of Shb-1 („Petal a kind from a middle; in is the put on respirator of Shb-1 („Petal
40”); a g is a respirator „Aster 2”40”); a g is a respirator „Aster 2”
Dust protecing suit for protecting from a caustic and poisonous dustDust protecing suit for protecting from a caustic and poisonous dust
Production clothes from a syntheticProduction clothes from a synthetic
THANK YOU FOR ATTENTION