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Human Karyotype- (Diploid= 2n) • Normal human- how many homologous pairs? • What is the sex? • How many chromosomes does each parent contribute?

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Human Karyotype- (Diploid= 2n). Normal human- how many homologous pairs? What is the sex? How many chromosomes does each parent contribute?. What if chromosomes fail to separate properly?. Nondisjunction Failure of chromosomes to separate properly during meiosis. - PowerPoint PPT Presentation

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Page 1: Human Karyotype- (Diploid= 2n)

Human Karyotype- (Diploid= 2n)

• Normal human- how many homologous pairs?

• What is the sex? • How many

chromosomes does each parent contribute?

Page 2: Human Karyotype- (Diploid= 2n)

What if chromosomes fail to separate properly?

Page 3: Human Karyotype- (Diploid= 2n)

NondisjunctionFailure of chromosomes to separate properly during meiosis

Page 4: Human Karyotype- (Diploid= 2n)

Abnormal Gametes result in abnormal diploid condition

SOMATIC TRISOMIESDown SyndromeTrisomy 13- cleft palate, eye brain circulatory defectsTrisomy 18- death in monthsTrisomy 16-death in months

SEX CHROMOSOMES TRISOMIESTurner Syndrome-X0- only viable monosomy in humans, Never mature sexually

Klinefelter Syndrome XXY

XYY- Super male- aggression

XXYYNOTE: the role of the Y chromosome…its presence yields malesness- otherwise default to female

Page 5: Human Karyotype- (Diploid= 2n)

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