how to live to 100+

How to Live How to Live

R e a l l y a L o n g L I f eR e a l l y a L o n g L I f e

May be 100+?May be 100+?

So Best to Start NowSo Best to Start Now

SIGNIFICANT HEALTH PRACTICESSIGNIFICANT HEALTH PRACTICES

PRACTICE PRACTICE RECOMMENDATION RECOMMENDATION1. 1. SleepSleep. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7-8 Hours7-8 Hours2.2. Eating Breakfast Eating Breakfast. . . . . . . . . . . . . . . . . . DailyDaily3. 3. Eating Between MealsEating Between Meals. . . . Rarely /NeverRarely /Never4. 4. Body WeightBody Weight. . . . . . . . . . . . . . . . . . . . . . . . . . Female: -5% to 9.99%Female: -5% to 9.99%

Male: -5% to 19.99%Male: -5% to 19.99%5. 5. Physical ActivityPhysical Activity. . . . . . . . . . . . . . . . . . Often - DailyOften - Daily6. 6. Drinking AlcoholDrinking Alcohol. . . . . . . . . . . . . . . . . . 0 - 20 - 27. 7. SmokingSmoking. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NoneNone

1A-2

BELLOC & BRESLOW STUDYBELLOC & BRESLOW STUDY0-243

56

7

Number ofHealth Practices

20 25 30 35 40 45 50 55 60 65 70 75 80

Hea

lth P

robl

ems

Les

s

Mor

e

1A-4

HEALTH PRACTICESHEALTH PRACTICES

MORTALITY

0 - 3 67 (45 + 22 Yrs)No. Habits Age at Death

4 - 5 73 (45 + 28 Yrs)

6 - 7 78 (45 + 33 Yrs)

1A-3

Mortality 1974

100

63

45

0

20

40

60

80

100

120

0-3 4-5 6-7

Health Habits

Rel

ativ

e R

isk

How to Live to 100+How to Live to 100+

Risk Factor RR %Pop. Pop-riskRisk Factor RR %Pop. Pop-risk

BP >150 vs. 120 2.1BP >150 vs. 120 2.1



BP >150 vs. 120 2.1BP >150 vs. 120 2.1Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4

How to Live to Maybe to a 100+How to Live to Maybe to a 100+


BP >150 vs. 120 2.1BP >150 vs. 120 2.1Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4Cigrets Cigrets >>1 pk/day 2.51 pk/day 2.5

How to Live to Maybe 100+How to Live to Maybe 100+


BP >150 vs. 120 2.1BP >150 vs. 120 2.1Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4Cigrets Cigrets >>1 pk/day 2.51 pk/day 2.5InactivityInactivity 2.0 2.0



BP >150 vs. 120 2.1 BP >150 vs. 120 2.1



BP >150 vs. 120 2.1 30BP >150 vs. 120 2.1 30



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363 Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 25 25



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363

Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 = X 25 = 6060



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363

Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 = X 25 = 6060Cigrets Cigrets >> 1 pk/day 2.5 30 1 pk/day 2.5 30



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363

Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 = X 25 = 6060Cigrets Cigrets >> 1 pk/day 2.5 X 30 = 1 pk/day 2.5 X 30 = 7575



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363

Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 = X 25 = 6060Cigrets Cigrets >> 1 pk/day 2.5 X 30 = 1 pk/day 2.5 X 30 = 7575Inactivity 2.0 60Inactivity 2.0 60



BP >150 vs. 120 2.1 X 30 = BP >150 vs. 120 2.1 X 30 = 6363

Chol. >268 vs. 218 2.4Chol. >268 vs. 218 2.4 X 25 = X 25 = 6060Cigrets Cigrets >> 1 pk/day 2.5 X 30 = 1 pk/day 2.5 X 30 = 7575Inactivity 2.0 X 60 = Inactivity 2.0 X 60 = 120120

How to Live to Possibly 100+How to Live to Possibly 100+

byby

Calorie Restriction andCalorie Restriction andMind over MatterMind over Matter


DESIGN OF FIRST STUDYDESIGN OF FIRST STUDY

Group A: Ad LibitumGroup A: Ad Libitum

Group B: 60% of Group AGroup B: 60% of Group A from 6 weeks onfrom 6 weeks on

How to Live to Maybe 100+How to Live to Maybe 100+DESIGN OF SECOND STUDYDESIGN OF SECOND STUDY

Group 1: Ad LibitumGroup 1: Ad Libitum Group 2: 60% of Group 1 from 6 weeks onGroup 2: 60% of Group 1 from 6 weeks on Group 3: 60% 6 weeks to 6 months then Ad Lib.Group 3: 60% 6 weeks to 6 months then Ad Lib. Group 4: Ad Libitum to 6 months then 60%Group 4: Ad Libitum to 6 months then 60% Group 5: Same Calorie intake, 60% ProteinGroup 5: Same Calorie intake, 60% Protein


Physiological Benefits of Physiological Benefits of Calorie RestrictionCalorie Restriction

Serum CholesterolSerum Cholesterol Mobilization of fatMobilization of fat Loss of muscle massLoss of muscle mass Loss of muscle functionLoss of muscle function


Pathological Benefits of Pathological Benefits of Calorie RestrictionCalorie Restriction

NephropathyNephropathyMonthsMonths 66 1818 2424 3636

Group A None or slight SevereGroup A None or slight Severe Lethal Lethal

Group B None or slight - No progressionGroup B None or slight - No progression - None- None


Pathological Benefits ofPathological Benefits ofCalorie RestrictionCalorie Restriction

CardiomyopathyCardiomyopathyGrade 3Grade 3

Group AGroup A 21% 21% Group BGroup B 0% 0%

How to Live to Perhaps 100+How to Live to Perhaps 100+

Pathological Benefits Pathological Benefits continuedcontinued

Testicular tumorsTesticular tumors18 months18 months

Group AGroup A Nearly all Nearly allGroup BGroup B Almost noneAlmost none

How to Live to Possibly 100+How to Live to Possibly 100+

Length of LifeLength of LifeMaximumMaximum AverageAverage

Group A 950 daysGroup A 950 days 2 years 2 years

Group B 1430 days 3 years Group B 1430 days 3 years


Benefits of Calorie RestrictionBenefits of Calorie RestrictionSlows aging and age related changesSlows aging and age related changes

e.g. cholesterol levels e.g. cholesterol levels mobilization of fatmobilization of fatvisionvisionjointsjointsinsulin sensitivityinsulin sensitivity

How to Live to Perhaps 100+How to Live to Perhaps 100+

Benefits of Calorie RestrictionBenefits of Calorie Restriction Preserves bone massPreserves bone mass Preserves muscle mass and muscle functionPreserves muscle mass and muscle function Preserves skin thicknessPreserves skin thickness Preserves immune functionPreserves immune function Preserves brain functionPreserves brain function

Newsweek Special EditionFall Winter 2001

How to live to About 100+How to live to About 100+

How healthy How healthy are you?are you?

Excellent healthExcellent health

Average healthAverage health

Poor healthPoor health


Attend Attend The Wellness ProgramThe Wellness Program

andandDo everything he says!Do everything he says!

how to live to 100+

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