how did it all start

HOW DID IT ALL START ?

DR. MOHAMMAD ABBAS

Assistant Professor& Orthopedic ConsultantFaculty of MedicineKing Abdulaziz University

NOVEMBER 2009

KNEE COURSE BY SMITH & NEPHEW IN TOURS, FRANCE.

THE TRUFIT PLUG FOR FOCAL CHONDRAL DEFECT WAS INTRODUCED BY DANIEL SARIS

FOR FOCAL CHONDRAL DEFECT

TRUFIT PLUG

MSCs

?FOR LARGER AREA OF CARTILAGE DEGENERATION ? TOTAL OSTEOARTHRITIS

TRUFIT PLUG

http://www.google.com.sa/url?url=http://www.djgelner.com/2013/06/so-you-want-to-write-bookthe-idea-hunt.html&rct=j&frm=1&q=&esrc=s&sa=U&ved=0CBcQwW4wAWoVChMIyti-weK6xwIVyHAaCh2rWARG&usg=AFQjCNHK1N_6-mlJYyoSbeuhHzim2yd16g

JANUARY 2010

THE IDEA AND PROCESS OF STARTING A SCIENTIFIC CHAIR THROUGH RACI @ KAU

A long tedious process to fulfill the RACI requirements

Sponsor. Distinguished stem cell professor. 3 years detailed plan. Organizational chart. Web page.

“ There is a huge gap between clinicians and scientists ”

Building up the team

http://www.google.com.sa/url?url=http://www.dawaaii.com/details.php&rct=j&frm=1&q=&esrc=s&sa=U&ved=0CDMQwW4wDzgUahUKEwj4xsz-8dLHAhWBNBQKHS5oANk&usg=AFQjCNEmE8Jmp5WrnHuLqir_oBexzx-Nzw

http://www.google.com.sa/url?url=http://www.microscope-repairs.co.uk/&rct=j&frm=1&q=&esrc=s&sa=U&ved=0CDkQwW4wEmoVChMI96Gun_LSxwIVgZYUCh3Q-Qd8&usg=AFQjCNHAlTDdzBTh8SxJTXkjHtOd0fu-vA

Stem cells ProfessorMolecular hematologist


http://www.bris.ac.uk/

Biochemistry professor. Consultant Hematologist Consultant Radiologist. PhD scientist in stem cell biology Orthopedic surgeons. Lab. specialist with

master in tissue culture.


الكرسي مشـــرفعباس. محمد د

أستـاذ الكرسي

أعضاء البحثية الكرسي المجموعات

مختبر الخاليا الجذعية

اإلدارة المالية

. وائل. د اكافينا

فاتن. دالسايس

. ممدوح. د أقاري . عطا. حازم د أ

محمد. دالكاف

مجموعة العظام أبحاث

عباس. محمد دعليشودري. د

درويش. حسام دحمدي. عمرو دالكاف. محمد د

مجموعة أمراض أبحاث

الدم السايس. فاتن د . قاري. ممدوح د أ

كالميجام. دجوثمان

السهلي. حنين أ

أبحاث مجموعةاألشعة

قطب. ممدوح د

أبحاث مجموعةالحيوية الكيمياء

. عطا. حازم د أ

. ممدوح. د أقاري

كالميجام. دجوثمانرهام. أالنونو

حنين. أالسهلي

بالتعاون مركز معالبحوث واالستشارات

Organizational chart

3 years detailed plan

Inauguration was on 22 Feb. 2012.

ESTABLISHING THE STEM CELL LAB. IN THE OPRATING THEATRE

Establishing a stem cells unit in CEGMR in KFRMC

Isolation & characterization of MSCs

Team members are regularly attending ICRS world congress

2015

2013

2012

Team Development

http://www.google.com.sa/url?url=http://www.finceramica.it/wps/wcm/connect/finceramica_en/finceramica/news/icrs2013+-+international+cartilage+repair+society&rct=j&frm=1&q=&esrc=s&sa=U&ved=0CB0QwW4wBGoVChMI3sHr3P3WxwIVJp3bCh1x0AM2&usg=AFQjCNFUq-BdeDFjaXaBoLwkRmAUPjbUBw

http://www.google.com.sa/url?url=http://www.biotissue.de/fr-frLatestNews,34.html&rct=j&frm=1&q=&esrc=s&sa=U&ved=0CC8QwW4wDWoVChMI8NjQ0v7WxwIVA0TbCh1AswKO&usg=AFQjCNGD1kHrQeUw_js0kZohYe-FmhQoOQ

http://www.google.com.sa/url?url=http://icrs-world-congress.org/news/cartilage-repair-showing-signs-of-promise/&rct=j&frm=1&q=&esrc=s&sa=U&ved=0CCkQwW4wCmoVChMIsba94P7WxwIViJrbCh2TSwRH&usg=AFQjCNGUYG9LZ_vZlt_h5kLjwZMuKnBWKg

Participation in ICRS courses

Radiologist MRI T2 mapping of cartilage course in Vienna 2012.

Orthopedic surgeons learning surgical procedures for cartilage regeneration.

Team Development

1- Isolation and Characterization of Mesenchymal Stem Cells from Bone Marrow of Osteoarthritis patients

2- Epigenetic analysis of osteoarthritis patients

3- Exome sequence analysis for osteoarthritis patients

4- Evaluation of ex-vivo cartilage regeneration with mesenchymal stem cells derived from the human bone marrow (hBM-MSCs) and synovial fluid (hSF MSCs) from osteoarthritis patients

Molecular Hematology Research

1- EFFECT OF ADRENALINE & VOLTAREN ON VIABILITY and PROLIFERATION of HUMAN MESENCHYMAL STEM CELLS

2- EFFECT OF MARCAINE & DEXAMETHASONE ON VIABILITY and PROLIFERATION of HUMAN MESENCHYMAL STEM CELLS

00.20.4

Effect of Adrenaline on the Viability and Proliferation

of Human MSCsMean

OD

0.14

0.17

Effect of Marcaine on the viability and proliferation

of human MSCsMean

OD

Biochemistry Research

The focus was on building up Articular Cartilage

Orthopedic Animal Research

Two projects done on rabbits for focal defects


Most recent research focuses on Induced Total Surgical Arthritis in Rabbits using

MSCs + Scaffolds


6 monthly report A yearly presentation to RACI

committee A yearly financial report

Fulfilling RACI follow up

A yearly meeting with the sponsor

PLEASE VISIT OUR WEB PAGE

how did it all start

Education