Hormone: Thyroxin

Overactivity (Too much hormone)- Increased metabolic rate- Increased food intake but loss of weight- Hyperthyroidism (Grave’s disease)- Goitre (swollen neck, maybe bulging

eyes)

Grave’s disease

Hormone: ThyroxinUnderactivity (Not enough

hormone)- Hypothyroidism (Hashimoto’s disease)- Reduced metabolic rate- Low food intake but gain of weight- Myxoedema (when onset in adults)- Cretinism- stunted mental and physical

growth (in children)- Can also cause a goitre

Puffiness (swelling) Fatigue Obesity Dry, thickened skin Mental impairment Thin, brittle hair

Protuberant abdomen

Short Stature Infertility Neurological

impairment Constant Fatigue Obesity

Hormone: Calcitonin

Overactivity- Increased Bone Ca, decreased Blood Ca- Tetany (nerve problems leading to muscle spasms

or cramps)

Underactivity- Increase Blood Ca, decreased Bone Ca- Osteoporosis (brittle bones)- Kidney stones

Hormone: Parathormone (PTH)

Underactivity- Low Blood calcium, High Bone Ca- Tetany

Overactivity- High Blood calcium, Low Bone Ca- Osteoporosis

Hormone: Insulin

Overactivity- Low blood sugar level ( ↓BSL)- Hypoglycemia

Underactivity- High blood sugar level ( ↑BSL)- Hyperglycemia - Diabetes

Hormone: Glucagon

Overactivity- High blood sugar level ( ↑BSL)- Diabetes

Underactivity- Low blood sugar level ( ↓BSL)- Hyper insulinism

Hormone: Growth Hormone

Overactive- Giantism (children - very tall)- Acromegaly (adults - bones & skin

thicken)

Underactive- Dwarfism (very short)

The man holding the baby in the photo is 8 ft, 2.5 inches tall

Dwarfism occurs when there is short supply of GH in childhood. There are two types of dwarfism – Lorrain and Frohlich’s

Overactive Goitre Hyperthyroidism Grave’s Disease

Underactive Goitre Hypothyroidism Hashimoto’s

Disease Myxoedema (adults) Cretinism (kids)

Overactive Tetany

Underactive Kidney Stones Osteoporosis

Overactive Kidney Stones Osteoporosis

Underactive Tetany

Overactive Hypoglycemia Hyperinsulinism

(insulin shock)

Underactive Hyperglycemia Diabetes

Calcitonin – Parathormone -

Over Reactivity

Under Reactivity

Blood Ca

Blood Ca

Blood Ca

Blood Ca

Tetany

Tetany

•Osteoporosis•Kidney Stones

•Osteoporosis•Kidney Stones

Blood Ca Blood Ca

Overactive Hyperglycemia Diabetes

Underactive Hypoglycemia Hyperinsulinism

Insulin – Glucagon -

Over Reactivity

Under Reactivity

BSL

•Hyperglycemia•Diabetes

BSL

•Hyperglycemia•Diabetes

Hypoglycemia

BSL

BSLBSL

Hypoglycemia

BSL

Overactive Giantism (children) Acromegaly (adults)

Underactive Dwarfism (Frohlich’s

and Lorrain)

Overactive Skin darkens

Under active Skin will not darken Most severe

condition is albinism

Overactive Unknown

Underactive Sterility

Overactive Cushing’s Syndrome

Underactive Addison’s Disease Decreased cortisol

and/or aldosterone production