high throughput screening| compound library | chemical library | screening library
DESCRIPTION
Screening Library, compound library, chemical library, high throughput screening for cell signaling and oncology research. These Chemical & Screening libraries are suitable for HTS, HCS and chemical biology applications.TRANSCRIPT
Selleck Screening Libraries offer easy, ready-to-use alternatives for the analysis of biochemical pathways and pharmaceutical-related applications. Our library contains a unique and diverse collection of over 700 bioactive compounds suitable for high-throughput screening (HTS), cell based high-content screening (HCS), chemical and
biological applications.
Library Advantages
Selleck Screening Libraries
Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews
NMR and HPLC to ensure the high purity
The collection of unique small molecules is focused on over 200 targets in more than 20 signaling pathways, such as PI3K / mTOR / Akt, MAPK and apoptosis. We provide compound position information, physical information, biological activityand chemical properties for each plate.
www.selleckchem.com/screening/screening-library.html
Chemical Library TotalA collection of 712 bioactive compounds.
Inhibitor LibraryA collection of 335 inhibitors.
Kinase Inhibitor LibraryA collection of 150 kinase inhibitors.
FDA Approved Drug LibraryA collection of 381 FDA approved drugs.
Natural Product LibraryA collection of 130 natural products.
Chemotherapeutic Agent LibraryA collection of 40 chemotherapeutic agents.
Tyrosine Kinase Inhibitor LibraryA unique collection of 86 tyrosine kinase inhibitors.
Chemical Library Total (96-well)
Chemical Library Total
Toll Free:(877)796-6397 www.selleckchem.com [email protected]
Phone:+1-832-582-8158---USA and Canada only---
A unique collection of 712 bioactive compounds for high throughput screening (HTS) and high content screening (HCS)
Bioactivity and safety confirmed by preclinical research and clinical trials
Some compounds have been approved by FDA
Includes most Selleck inhibitors, APIs, natural products and chemotherapeutic agents Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews NMR and HPLC to ensure the high purity
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������Chemical Library Total
Product
712
Compounds
L1700
Catalog No.Powder Pre-dissolved in DMSO
Size
You can select compounds, quantities, format������������ ����plate map and concentration to meet your specific requirement.
Customize Your Library
Num
ber o
f com
poun
ds
0
100
200
400
300
Inhibitors Kinase Inhibitors FDA Approved Drugs Natural Products Chemotherapeutic Agents
335
150
381
130
40
Tyrosine Kinase Inhibitors
86
Download the Library TotalSDF
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Inhibitor Library
Terrific Quality, Validation, Customer Review & Tech Support
Inhibitor Library (96-well)A unique collection of 335 inhibitors for high throughput screening (HTS) and high content screening (HCS) Bioactivity and safety confirmed by preclinical research and clinical trialsSome inhibitors have been approved by FDA
Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews
NMR and HPLC to ensure the high purity
Targets PI3K, VEGFR and RTK pathway, HDAC, Aurora Kinase, CDK and Cell Cycle regulators, Integrase/Proteasome etc
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Num
ber o
f inhi
bito
rs
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������������ ��������Inhibitor Library 335 L1100
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Product Compounds Catalog No.Powder Pre-dissolved in DMSO
Size
18
11
3 3
1
1 1 1 1 1 1 1 1 1 1 1 1 1 1
12
2 2 2 2 2 2 2 2
27
16 1615
14 14
11
7 7
1
88
4
4 4 4
2 2
121211
1 1 1 1 1 1 1
3
3333
7 7
44
2 2
11
5
5 5
5666
66 6
31
99910
0
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
0
2
4
6
8
10
PI3K
mTOR
AKT
GSK-3
DNA-PK
&'
S6 kinase
VEGFR
EGFR
PDGFR
c-Kit
!* ��
Bcr-Abl
SRC
IGF-1R
HER2
ALK
Syk
Tie-2
/��/;
FGFR
HIF
VDA
Bcl-2
TNF-alpha
p53
Survivin
JAK
STAT
#<= &>?
Pim
M?
Raf
JNK
Kinesin Spindle Protein
Aurora Kinase
HDAC HSP
Topoisomerase
Sirtuin
Antimetabolites
CDK
�!����Q��/���"����
PARP
PLK
ROCK
CHK
Telomerase
PKC
�Z&�[Z&synthesis
Dihydrofolate Reductas
5-HT receptor
COX
HistamineReceptor
Gamma-secretase
mAChRs
GABAreceptor
Dopamine Receptor
Hedgehog
Wnt
AdrenergicReceptors
ETA-receptor
5-alpha-reductase
Estrogen Receptor
AndrogenReceptor
RAAS
Aromatase
CalciumChannel
Sodium Channel
PotassiumChannel
P450
Factor Xa
PDE
Aminopeptidase
Dehydrogenase
Proteasome
HCVProtease
DPP-4
HIV Protease
CCR5
ReverseTranscriptase
CFTR
Integrase
Others
Download the Inhibitor LibrarySDF
Download the Inhibitor LibraryXLSX
Terr
Download SDFSDF
Download comprehensive documentation on this library:
Kinase Inhibitor Library (96-well)
Kinase Inhibitor Library
Toll Free:(877)796-6397 www.selleckchem.com [email protected]
Phone:+1-832-582-8158---USA and Canada only---
A unique collection of 150 kinase inhibitors for high throughput screening (HTS) and high content screening (HCS)
Bioactivity and safety confirmed by preclinical research and clinical trialsSome kinase inhibitors have been approved by FDA
Targets kinases such as RTKs, PI3K, Aurora Kinase, CDK and MEK
Most are ATP competitive
Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews
NMR and HPLC to ensure the high purity
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Customize Your Library
Num
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ase
inhi
bito
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������������ ��������Kinase Inhibitor Library 150 L1200������
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Product Compounds Catalog No.Powder Pre-dissolved in DMSO
Size
18
28
11
3 32
1514
4
11 11
7 7
10 10
8
22
12
15
666
8
2
44
2 21 1 1 1
0
2
4
6
8
10
12
14
16
18
20
22
24
26
28
PI3K
mTOR
AKT
GSK-3
&'
VEGFR
EGFR
PDGFR
JAK
M?
Raf
#<= &>?
c-Kit
!* ��
Bcr-Abl
SRC
IGF-1R
HER2
ALK
Syk
Tie2
/��/�?
FGFR
Aurora
CDK
PLK
PKC
S6 Kinase
TGF-beta
CHK
JNK
Others
Download the Kinase InhibitorLibrary SDF
Download the Kinase InhibitorLibrary XLSX
www.selleckchem.co
DownloadLibrary SDSDF
Download comprehensive documentation on this library:
Tyrosine Kinase Inhibitor Library (96-well)A unique collection of 86 tyrosine kinase inhibitors for high throughput screening (HTS) and high content screening (HCS)
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������������ ��������Tyrosine Kinase Inhibitor Library 86 L1800 ������
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Product Compounds Catalog No.Powder Pre-dissolved in DMSO
Size
Terrific Quality, Validation, Customer Review & Tech Support
Bioactivity and safety confirmed by preclinical research and clinical trials
Some tyrosine kinase inhibitors have been approved by FDA
Targets tyrosine kinases such as EGFR, VEGFR, SRC, c-Met and JAK
Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews
NMR and HPLC to ensure the high purity
Num
ber o
f tyr
osin
e kin
ase
inhi
bito
rs
Tyrosine Kinase Inhibitor Library
30
15
12 12
8
18
6
43
1
109 9
7
2
6
1
0
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
VEGFR EGFR PDGFR JAK Rafc-Kit !* �� Bcr-AblIGF-1RHER2 ALKSyk SRCTie2 /��/�?FGFR Wee1
Download the Tyrosine Kinase Inhibitor Library SDF
Download the Tyrosine Kinase Inhibitor Library XLSX
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DownloadInhibitor LiSDF
Download comprehensive documentation on this library:
FDA Approved Drug Library
FDA Approved Drug Library (96-well)A unique collection of 381 FDA approved drugs for high throughput screening (HTS) and high content screening (HCS)
Helps to locate new targets for old drugs
Bioactivity and safety confirmed by clinical trials
All compounds have been approved by FDA
Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews
NMR and HPLC to ensure the high purity
Related to oncology, cardiology, anti-inflammatory, immunology, neuropsychiatry, analgesia etc
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������������ ��������FDA Approved Drug Library 381 L1300
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������
Product Compounds Catalog No.Powder Pre-dissolved in DMSO
Size
0
10
20
30
40
50
60
70
80
65
77
40
2531
20
69
59
8
Cancer
Infection
Endocrinology
��"Q��!Disease
Inflammation
Immunology
NeurologicalDisease
CardiovascularDisease
RespiratoryDiseases
Num
ber o
f FD
A ap
prov
ed d
rugs
Toll Free:(877)796-6397 www.selleckchem.com [email protected]
Phone:+1-832-582-8158---USA and Canada only---
Download the FDA Approved Drug Library SDF
Download the FDA ApprovedDrug Library XLSX
www.selleckchem.co
DownloadDrug LibraSDF
Download comprehensive documentation on this library:
Natural Product Library (96-well)
Natural Product Library
A unique collection of 130 natural products for high throughput screening (HTS) and high content screening (HCS)
Structurally diverse, bioactive and cell permeable
Rich documentation with structure and IC50
NMR and HPLC to ensure the high purity
Library includes:
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Customize Your Library
������������ ��������
������������ ��������Natural Product Library 130 L1400
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Product Compounds Catalog No.Powder Pre-dissolved in DMSO
Size
Steroid saponins
Benzoquinones
Tannins
Alkaloids
PPGs
Penzaldehydes
Saccharides
Anthraquinones
Phenanthraquinones
Phenylcarbinols
Pyrimidines
Flavones
Synthetic derivatives
Phenethylamines
Acid amides
Steroids
Peptides
Terrific Quality, Validation, Customer Review & Tech Support
Download the Natural ProductLibrary XLSX
Download the Natural Product Library SDF
Te
Download Library SDSDF
Download comprehensive documentation on this library:
Chemotherapeutic Agent Library
Chemotherapeutic Agent Library (96-well)A unique collection of 40 chemotherapeutic agents for high throughput screening (HTS) and high content screening (HCS)
Structurally diverse, medicinally active and cell permeable
Rich documentation with structure, IC50 and customer reviews
NMR and HPLC to ensure the high purity
Bioactivity and safety confirmed by clinical trials
Some agents have been approved by FDA for both oncological and non-oncological purposes
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������������ ��������Chemotherapeutic Agent Library 40 L1500
������
������
Product Compounds Catalog No.Powder Pre-dissolved in DMSO
Size
0
2
4
6
8
10
12
14
6
13
34 4
10
Alkylatingagents
Anti-metabolites
Plant alkaloidsand terpenoids
Topoisomeraseinhibitors
Cytotoxicantibiotics
Other antitumouragents
Num
ber o
f che
mot
hera
peut
ic ag
ents
Toll Free:(877)796-6397 www.selleckchem.com [email protected]
Phone:+1-832-582-8158---USA and Canada only---
Download the ChemotherapeuticAgent Library XLSX
Download the ChemotherapeuticAgent Library SDF
www.selleckchem.co
Download thAgent LibrarSDF
Download comprehensive documentation on this library:
Guaranteed Quality and Support
Guaranteed Quality and Support
The purity of each reagent in Selleck screening libraries is confirmed by HPLC and H-NMR.In addition, all libraries are supplied with a detailed documentation set including compound position information, physical information, biological activity and chemical properties in SDF and Excel files.
Certificate of AnalysisMolecular Formula: C17H15BrClFN4O3
Molecular Weight: 457.68 CAS No.: 606143-52-6 Storage: at -20℃ 2 years
Molecular Structure:
AU
0.00
0.50
1.00
1.50
2.00
2.50
3.00
inutes2.00 4.00 6.00 8.00 10.00 12.00 14.00 16.00 18.00 20.00 22.00 24.00 26.00 28.00 30.00
15.6
7616
.152
17.8
75
11.
693
8.3
79 7
.892
7.7
22 7
.589
7.5
87 7
.584
7.5
81 7
.252
7.2
51 7
.247
7.2
30 7
.228
7.2
25 6
.353
6.3
43 6
.331
6.3
21
4.6
94 4
.691
3.8
82 3
.839
3.5
33 3
.311
3.3
09
2.4
83 2
.479
2.4
76 2
.475
2.0
63 2
.059
-0.0
25 -0
.028
1.00 0.96
1.00 0.94 1.00 3.01 2.00
2.00 1.00 1.00 0.91
12 10 8 6 4 2 0 >>
����=���� ��*�]
HN
Cl
BrFNN
HN O
OHO
USER: -- DATE: Apr 2 2011
Nuts - $S100810 AZD6244
Std proton;blank line86723 , 12561 :d1STP 4.4123 :1FO 5608 :1WS794.001 :2F536.993 :1F
0.0 :BL 8 :ANces 0.2 :DPsu 2.7 :WPlup2s :XE
Physical and chemical properties
S1008 AZD6244 (Selumetinib)
SD File
XLSX File
Having doubts on Selleck’s products? Following data from our customers is to assure you the high quality of Selleck Screening Libraries.
Data from [ Nature Biotechnology����_ "�!`j�{|���*]�}Vorinostat (SAHA) purchased from Selleck
Data from [ Cancer Cell����_~���j�{|���<}Rapamycin (Sirolimus) purchased from Selleck
Data from [ Nature����_Z����Q��j�]=|{]=*{��}AZD6244 (Selumetinib) purchased from Selleck
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Customize Your Library
Customize Your LibraryA cherry pick service is available to let you customize your own libraries.
Please contact us at [email protected] to check the details of your library.
You could select
Specific Compounds Quantities Format ������������ ���������� Plate map Concentration
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