MAT 95 XP

High Resolution Mass Spectrometerfor

Target Compound Analysis

High Resolution Mass Spectrometerfor

Target Compound Analysis

MAT 95 XP

3

Finnigan MAT 95 XPHRGC – HRMS

Finnigan MAT 95 XPHRGC – HRMS

The most powerful mass spectrometer for alldioxin and P.O.P. laboratories

Highly flexible GC-MS system

Fully automated regardless of injector type

Multicolumn operation

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Mass SpectrometerMass Spectrometer

AutotuningAutotuning assures optimizedinstrument performance with mini-mal user interaction at any resolu-tion setting – fast, automated andreproducible.

Mass CalibrationThe MAT 95 XP requires only ONEcalibration table. The uniqueThermo Finnigan patented fieldprobe control enables this feature.

Advantages of this technique andthe single calibration are:

Simply forgetmass calibration

on theMAT 95 XP !

Long-term stability

Ease of use

Independent of allscan parameters

Applicable to allionization modes

Easy switchingbetween differentsample types

MAT 95 XP: Source control

IonSource

Magnet

EntranceSlit

Resolution AdjustmentResolution Adjustment

8000

12000

4000

0

Res

olut

ion

1 5 Number of acquisition10

Mass resolution is adjustablemanually or automatically byvarying only the entrance and exitslit. The resolution adjustmentfrom R=1,000 to R=10,000 showsexcellent transmission.

The resolution is calculated andstored for documentation in theanalysis LOG file within each MIDtime window.

This unique feature makes youranalysis perfectly reliable. It iseasy to meet the quality controlrequirements of different analyticalmethods.

316.7 317.0 317.3

316.9824

R = 10,000R = 10,000

10 %10 %

100 %100 %

R = 1,000R = 1,000

316.7 317.0 317.3

316.7 317.3

MAT 95 XP: Resolution adjustment

MAT 95 XP: Resolution stability over 48 hoursExit Slit

Detector

ESA

5

EPA Methods 1613 and 8290for dioxins and furansEPA Methods 1613 and 8290for dioxins and furans

combination with a secondaryelectron multiplier.

Reporting of mass traces and quan-tification following EPA Methods1613 and 8290 is standard andfully automated.

The MAT 95 XP offers the ultimatedynamic range for highly specifictarget compound analysis coveringmore than 5 orders of magnitude.This important capability is basedon the Thermo Finnigan patented± 20 kV conversion dynode in

From instrument setupto quantification and reporting:

Complete solutions followingEPA Methods 1613 and 8290 areprovided with the MAT 95 XP !

0

20

40

60

80

100tetra penta hexa hepta octa

Segment 1 Segment 2 Segment 3 Segment 4 Segment 5

Inte

nsity

(%

)

6

Dioxins/Furans: Quantification

Dioxins/Furans: QC Analysis

EPA Method 1668for PCB analysis

EPA Method 1668for PCB analysis

Dioxin and PCB analyses arefrequently requested for the samesample. Therefore, it is mandatoryto change GC methods andmultiple ion detection (MID) setupswithin the same analysis sequence.

With the MAT 95 XP, methods canbe changed, even in an unattend-ed overnight sequence. Highestflexibility is achieved with turnkeysolutions for quantification of alldioxins and PCBs.

Measurement quality is closelyrelated to reproducibility. Perform-ing the same PCB measurement25 times in fully automated mode,a standard deviation of less than6 % is achieved routinely.

0

20

40

60

80

100

deca

hepta

hexa

pentatetra

Segment 1 Segment 2 Segment 3 Segment 4 Segment 5

Inte

nsity

(%

)

Number of measurement1 5 15100

50000

100000

150000

200000

250000

Total ion current intensity

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PCBs: Reproducibility of measurements

PCBs: High resolution GC-MS ranging from Cl4 to Cl10

Similar to dioxins and furans, BFRsenter the same ecological chainand are found in biological sampleslike water, milk or air.

The brominated diphenylethers(PBrDPE), one important class of

BFRs, are of high interest becauseof their similarity to PCBs.

Due to the fragmentation of thePBrDPE (loss of 2 Br), some ionswould require resolution power of45,000 for complete separation.

To obtain unambiguous resultsat lower resolution (R=10,000) itis advantageous to measure eithertwo ratio masses or a high massmolecular ion.

Inte

nsity

(%

)

Mass [amu]721.30 721.35 721.40 721.45 721.50

20

40

60

80

100

0

Nona-BrDPE[M-2Br]

C12HOBr7

Hepta-BrDPE

[M]C12H3OBr7

RP = 10,000RP = 45,000

BrDPE: Quantification

BrDPE: Isotope pattern calculation

BFRAnalysis of Brominated Flame RetardantsBFRAnalysis of Brominated Flame Retardants

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Analysis of Toxaphenesby negative chemical ionization

Analysis of Toxaphenesby negative chemical ionization

Toxaphenes were applied world-wide as pesticides until banned inthe early ‘90s. Because of theirslow degradation it is a necessity toanalyze these toxic compounds inour food chain, especially in fish.

Low level detection can only beaccomplished by negative chemicalionization (NCI) at low ion sourcetemperatures.

The MAT 95 XP excels at NCI: itcan reproducibly detect and quan-tify at low femtogram levels. Theresponse curve shows linearity forBGVV 2 toxaphene standard over4 orders of magnitude.

Toxaphenes: Linearity

Toxaphenes: MID setup example

9

Corr = 0.9994

0

200000

400000

600000

Area

0 10000 20000 30000 Amount [fg]40000

17.30 17.70

50 fgm/z 412.8150

16000

8000

0 1000500

10

The MAT 95 XP high resolutionsector field instrument is integra-ted into XcaliburTM, the uniqueWindows® NT-based softwareused worldwide on most ThermoFinnigan products.

The Sequence Setup allows auto-mated, unattended batch acquisi-tion of samples. Different sampletypes can be alternated in onesequence.

Special evaluation programsdesigned for high resolution massspectrometric applications areavailable by mouse click from theXcaliburTM main page.

Sequence SetupSequence Setup

100

50

00 10 20 30

100

50

00 10 20 30

100

50

00 10 20 30

1 2 3 ➔4 5 6

7 8 9

* 0 #

➔

➔

➔

OO

OO

OO

OOOO

CC

CH4CH4

CH4CH4

H3CH3C

InstrumentSetup

ProcessingSetup

LibraryBrowser

QuanBrowser

QualBrowser

SequenceSetup

XcaliburTM: Sequence Setup and status control

Dioxin Software PackageDioxin Software Package

The Target Compound Quanti-fication program was developedspecially for isotope dilution quan-tification. User interaction allowsfor the highest level of flexibilty.

A starting package containinga wide variety of quan files, in

accordance with methods such asEPA1613 or EN1948, is provided.

Together with the Response andReporter program the new TargetCompound Quantification packageis designed for both, beginnersand advanced users, meeting the

needs of any analytical laboratory.

For email reporting, sample resultscan be saved by mouse click eitheras HTML documents (TargetCompound Quantification) or asWord documents (Reporter). 11

Target Compound Response Program: CS1 - CS5 calibration

Target Compound Quantification: Setup

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System ConfigurationSystem Configuration

MAT 95 XP Standard Version

Full acceleration potential for all ionization modes

Resolution > 60,000

Mass range > 3,500 Da at maximum acceleration potential

Scan cycle time 0.2 s/decade

Multiple ion detection with 33 time segments per analysis and31 masses per time segment

Continuously variable entrance and exit slits with piezo effect actuators

Gas chromatograph

Differential pumping system with 3 turbomolecular pumps

Options: AutosamplerFast column exchange unitCIS 4 cold injection system

Dioxin Package A

MAT 95 XP dioxin version, including one gas chromatograph,one autosampler and one DB5MS fused silica column.

Options: Fast column exchange unitCIS 4 cold injection system

Dioxin Package B

MAT 95 XP dioxin version, including two gas chromatographs, twoautosamplers, one DB5MS and one Rtx2330 fused silica column.

Options: Fast column exchange unitCIS 4 cold injection system

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Installation RequirementsInstallation Requirements

SuppliesPower230 V +6% / -10%, 50 or 60 Hz.Three phase AC, 25 A each

GasesHelium with > 99.998% purity

Cooling water1 l/min, optionally closed loopsystem

EnvironmentTemperatureShould not vary more than ± 2ºC.Tolerable range between 15ºC and26ºC (59ºF/79ºF); best at 21ºC (70ºF).

Air conditioning loadApproximately 4.5 kW

2000 mm

1700 mm

1925

mm

400 mm

400

mm

WaterCooler

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InformationInformation

Web page

Simply visit our Web page for additional information aboutall instruments, new software releases, poster compilations,training schedules, service, support, etc.

www.ThermoFinniganMAT.de

Training

Although Thermo Finnigan’s instruments are easy to use,their full potential can best be achieved after complete famil-iarization. Training courses are conducted by experiencedpersonnel. The MAT 95 XP operating manual should allow aneasy start with the different measuring modes.

Support

Local users’ meetings in different countries provide the latestinformation about developments and applications.

Engineers and application chemists are available for supportand discussions whether they are attending a users’ meeting, aconference or a trade show. For any support, you have directaccess by telephone, telefax or internet.

Dioxin Special

For a quick start with your new high resolution massspectrometer we offer three to five days of on-site training.Furthermore, Thermo Finnigan can arrange training for samplecollection, clean-up of samples and laboratory organization.

Thermo Finnigan MAT GmbH, Barkhausenstr. 2, 28197 Bremen/Germany • Phone +49-421- 5493-0 • Fax +49-421- 5493-396

Worldwide represented byAustralia, Thermo Finnigan Australia Pty. Ltd, Unit 14, 38-46 South St., P.O. Box 239, Rydalmere, NSW 2116 • Phone +61-2-98989000 • Fax +61-2-98989800Belgium, Thermo Finnigan BVBA, Groenenborgerlaan 84, 2610 Antwerp-Wilrijk • Phone +32-3-8250670 • Fax +32-3-8250692France, Thermo Finnigan France SA, Hightec Sud, 12 av. des Tropiques, ZA de Courtaboeuf - BP 141, 91944 Les ULIS Cedex • Phone +33-1-69188810 • Fax +33-1-69299382Germany, Thermo Finnigan GmbH, Boschring 12, 63329 Egelsbach • Phone +49-6103-408-0 • Fax +49-6103-408-222Italy, Thermo Finnigan APG Italy, Strada Rivoltana, 20090 Rodano (MI) • Phone +39-02-95059-1 • Fax +39-02-95320-370Japan, ThermoQuest K.K., Nishi-Shinjuku Toyokuni Bldg., 2-5-8 Hatsudai, Shibuya-ku, Tokyo, 151-0061 • Phone +81-3-3372-3001 • Fax +81-3-3372-7051The Netherlands, Thermo Finnigan BV, Druivenstraat 33, 4816 KB Breda • Phone +31-76-5878722 • Fax +31-76-5714171People’s Republic of China, Thermo Finnigan Beijing Rep. Office, Room 912, Ping-an Mansion, No. 23, Finance Street, Beijing 100032;Phone +86-10-66210-839, -846 • Fax +86-10-66210-851Spain, Thermo Finnigan S.A., Avenida de Valdelaparra 27, Edificio Alcor, planta 2, 28108 Alcobendas (Madrid) • Phone +34-91-6574930 • Fax +34-91-6574937Sweden, Thermo Finnigan AB, Pyramidbacken 3, 141 75 Kungens Kurva • Phone +46-8-55646800 • Fax +46-8-55646808United Kingdom, Thermo Finnigan UK, Paradise, Hemel Hempstead, Herts HP2 4TG • Phone +44-1442-233555 • Fax +44-1442-233667U.S.A., Thermo Finnigan LLC, 355 River Oaks Parkway, San Jose, CA 95134 • Phone +1-408-965-6800 • Fax +1-408-965-6010

In countries not contained in the above list Thermo Finnigan is represented by renowned instrument distributors.

Information and specifications herein are subject to revision without prior notice.Availability of components and options subject to verification by local representative.

Copyright 2001© by Thermo Finnigan MAT GmbH, a Thermo Electron business. All rights reserved. Printed in Germany. 07/01 Part No. 1990731