hemorrhagic bowel syndrome (hbs) - משרד החקלאות units/veterinary... · 2016-02-29 ·...
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Hemorrhagic bowel syndrome Hemorrhagic bowel syndrome
(HBS)(HBS)
S. Perl, J.Brenner, D. Elad, D. Lahav,
N. Edery and N. Sheikhat.
Kimron Veterinary Institute
P.O.Box12, Bet Dagan 50250
Veterinary Symposium, Israel 2004
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Hemorrhagic bowel syndrome Hemorrhagic bowel syndrome
(HBS)(HBS)
� HBS is a sporadic acute intestinal disease of
milking cows
� Characterized by large blood clots in the intestinal lumen
� Obstruction and enlargement of the bowel
� Synonyms: “bloody gut”
“jejunal hemorrhagic syndrome”
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS) (HBS) � Clinically:
clotted blood in feces
profound depression
sudden drop in milk production
loss of appetite
abdominal distention and pain
severe anemia
extreme weakness
death within 24 hours
cases of sudden death are often reported
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS)(HBS)
� Ultrasound exams
dilated loops of small intestine
clotted blood in the lumen
� Treatment
medical or surgical unsuccessful
HBS has a high fatality rate
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS(HBS� First reported in 1991by Dr.Bruce Anderson in Idaho in five high-producing Holstein cows from one dairy farm
- Sub-mucosal hematomas in the jejunum(4)
- Ruptured hematoma with exanguination(1)
� Since 1991 HBS cases were diagnosed in various states in the US: Minnesota, New York
Pennsylvania, Washington, Colorado, Iowa etc.
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS)(HBS)� Evaluated nationally for the first time during the
National Animal Health Monitoring System’s Dairy 2002 study in the USA
� Farmers/ vets. from 21 States were asked to
describe their familiarity with HBS
only 1% have knowledge about the disease
2.5% had some basic information
8.7% recognized the name
87.8% had not heard of HBS
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS)(HBS)� Etiology:
not known
Clostridium perfringens Type A suggested
- has been found in 85% of HBS cases
- not yet determined as primary involved
because Clostridium Type A is common in
the environment and in bovine GI tract
Aspergillus fumigatus recently implicated
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS)(HBS)
� Proposed risk factors for HBS:
- increasing milk production
- feeding a high carbohydrate ratio
- decrease in dietary fiber
- most cases in winter season
- poorly fermented ensiled feeds
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HBS - Case of 2001
מכון ולקני
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Obstructed lumen of the small intestine by blood clots
HBS - Case of 2001
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HBS - Case of 2003
Obstructed lumen of the small intestine by blood clotsכפר שמואל
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HBS- case of 2004
Obstructed lumen of the small intestine by blood clots
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HBS – case of 2004
Obstructed lumen of the small intestine by blood clots
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Obstructed intestinal segment
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Blood clots in the intestinal lumen
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS) cases in Israel(HBS) cases in Israel
(10/08/00) 3
(22/08/96) 6
5
(22/06/94) 8
4
4
(27/09/95) 6
(23/11/95) 6
(25/09/98) 3
גיל
425339
384090
351536
339948
348615
344637
342069
340286
325021
ח"דו' מס
23.02.04
11.02.03
13.06.02
22.06.02
15.05.02
09.04.02
13.03.02
21.02.02
9.11.010
- PMתאריך
כפר שמואל
כפר שמואל
ניר עוז
פלמחים
לוטן
גבעתי
אורטל
ניר גלים
בית דגן
ישוב
E. Coli hemolitic
NPB found
ND
Cl. Perfringens
ND
ND
NPB found
NPB found
NPB found
בקטריולוגיה
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Histology
Normal Necrosis and hemorrhage
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Jejunal mucosal necrosis and hemorrhage
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS)(HBS)Conclusions
� HBS is a highly fatal intestinal disease
� Intraluminal hemorrhage and obstruction
� Adult cows on the second lactation or more
� Primary cause not yet determined
� HBS is under diagnosed in Israel
� Tens of dead cows are incinerated each day at the
“Ein Hamifratz” incinerator with out PM examination
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Hemorrhagic bowel syndromeHemorrhagic bowel syndrome
(HBS)(HBS)
Thanks to the clinicians:
, אלפרטניר ' דר, דגוניאילן ' דר, נחום שפיגל' דר
מאיר למפרט' תמיר גושן ודר' דר, חןגילד' דר