healthtap ebola townhall - ebola news and update

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EBOLA OUTBREAK UPDATE October 26, 2014 John Leander Po MD, PhD Clinical Associate Professor ID Fellowship Program Director Division of Infectious Diseases University of Arizona College of Geoffrey Rutledge MD, PhD Chief Medical Officer and Cofounder, HealthTap + [email protected]

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HealthTap Ebola National Townhall - news and updates for HealthTap doctors led by Infectious Disease experts.

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Page 1: HealthTap Ebola Townhall - Ebola News and Update

EBOLA OUTBREAK UPDATE

October 26, 2014

John Leander Po MD, PhDClinical Associate Professor

ID Fellowship Program Director

Division of Infectious Diseases

University of Arizona College of Medicine

Geoffrey Rutledge MD, PhDChief Medical Officer and Cofounder, HealthTap+

[email protected]

Page 2: HealthTap Ebola Townhall - Ebola News and Update

Ebola Update: What every doctor needs to know

Agenda•Introduction •Ebola background and update•Q & A for doctors•Patients’ most commonly asked questions•Key takeaway points for doctors•Closing remarks

Page 3: HealthTap Ebola Townhall - Ebola News and Update

• Filoviridae Family • Ebola, Marlburg

• Genus: Ebolavirus• Pleomorphic, branched filament

• 14,000nm/80nm• Enveloped ss RNA

• Glycoprotein=TIM-1 receptor binding (epithelial cells)• Respiratory tract, conjunctiva, skin,

body cavities• Overwhelming production of virus

• Cytokine storm• Vasc. Leakage, hemorrhage,

hypotension, multiorgan failure

Ebola VirusBiology

Page 4: HealthTap Ebola Townhall - Ebola News and Update
Page 5: HealthTap Ebola Townhall - Ebola News and Update

• Supportive– Fluids, electrolytes, O2– Secondary infections

• Challenges– Nebulous symptoms– Catch-up due to misdiagnois– Personal Protective clothing

Ebola VirusTreatment

Page 6: HealthTap Ebola Townhall - Ebola News and Update

New York Times August 4, 2014

2014 Ebola Epidemic Context

Page 7: HealthTap Ebola Townhall - Ebola News and Update

How did it get so bad?!?

• Poorest countries in the World

• Ebola unfamiliarity to Western Africa

• Infection prevention: foreign concept

• Cultural practices fosters contact

• Fear of hemorrhagic virus infections

• Absence of vaccine or treatment

• Easy and rapid global travel

• Lackluster world response

Page 8: HealthTap Ebola Townhall - Ebola News and Update

Ebola VirusInfection Control

• Barrier Control– Personal protective clothing– Infection control measures

• Sterilization, disinfection, incineration• Negative pressure, HEPA filtration• In-room lab equipment

• Cumbersome

Page 9: HealthTap Ebola Townhall - Ebola News and Update
Page 10: HealthTap Ebola Townhall - Ebola News and Update
Page 11: HealthTap Ebola Townhall - Ebola News and Update
Page 12: HealthTap Ebola Townhall - Ebola News and Update

Context with other major infections

Influenza virus (4)Up to 49,000 deaths

Page 13: HealthTap Ebola Townhall - Ebola News and Update
Page 14: HealthTap Ebola Townhall - Ebola News and Update

Dress rehearsals: Dr. Po demonstrates "Donning & Doffing"

Page 15: HealthTap Ebola Townhall - Ebola News and Update

Key Takeaway points: What every doctor should know about Ebola

- What is Ebola virus and what makes this event unique?

- How is it transmitted and how do protect ourselves?

- What the US is currently doing to avoid the spread of the disease in this country?

- What do we tell our patients to limit their fears of the disease?

Page 16: HealthTap Ebola Townhall - Ebola News and Update

What is Ebola virus and what makes this event unique?

–Ebola virus is a filamentous virus that was originally discovered in central Africa in 1976 and causes a life-threatening hemorrhagic fever syndrome.

–This year's outbreak is the largest Ebola virus epidemic ever recorded in human history, affecting the poorest part of Africa: Guinea, Sierra Leone, and Liberia.

Page 17: HealthTap Ebola Townhall - Ebola News and Update

How is it transmitted and how do protect ourselves?

–The virus is spread by droplets of body fluid that contact uninfected patients, or by contacting surfaces contaminated with the virus.

–To protect ourselves, we limit the number of people who come to close contact with infected patients, don and doff personal protective equipment and institute quarantines when appropriate.

Page 18: HealthTap Ebola Townhall - Ebola News and Update

What the US is currently doing to avoid the spread of the disease in this country?

–CDC has initiated fever screening stations at five US international airports where all incoming flights from Africa are to land. Protocols to isolate and care for infected patients have been devised and are continually being revised when appropriate at the national, state, county and local levels.

Page 19: HealthTap Ebola Townhall - Ebola News and Update

What do we tell our patients to limit their fears of the disease?

–Patients need to understand the context of this infection and how remote it is to become infected with the Ebola virus compared to other infections that have greater morbidity such as influenza virus infection, measles, and mumps.

Page 20: HealthTap Ebola Townhall - Ebola News and Update

Frequently-asked questions on Ebola

1. Is there a cure for Ebola?2. How is Ebola treated?3. Are immunosuppressed people at

greater risk of contracting Ebola?4. Does being on blood thinners put

people at greater risk of death from Ebola from bleeding?

5. What are early and late symptoms of Ebola?

6. How can I protect myself against Ebola?

7. Can Ebola be spread by animals?8. Why hazmat suits if Ebola isn't

airborne?9. Is it safe for me to travel to Dallas

right now?

10. Are we close to finding a cure for Ebola?

11. Will Ebola go viral?12. How long does the Ebola virus live?13. Where did the Ebola virus originate?14. What's the difference between Ebola

and Simian Hemorrhagic Fever?15. What's the difference between Ebola

and the Marburg virus?16. Can virus latency remain with Ebola, so

people can infect even after quarantine?

17. Can people who have already been infected with Ebola get it again?

18. How is Ebola being contained?

Page 21: HealthTap Ebola Townhall - Ebola News and Update

Medical Expert Network

- 64,000+ US-licensed doctors in 137 specialties helping people- Millions of informational answers to free member questions - Tens of millions of visitors to HealthTap.com helped each month- Doctor answers served more than 2 Billion times! - Answers, Tips, Checklists, Health News, App Reviews- Curbside Consults with your colleagues- Give and get Peer Review of your Answers- Professional profile and free custom URL

- US-licensed doctors in good standing are welcome to join - doctors, dentists, podiatrists, clinical psychologists and PharmD pharmacologists

- Apply to join: bit.ly/HTapDoc

Page 22: HealthTap Ebola Townhall - Ebola News and Update

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- Apply: bit.ly/HTapPrime

Page 23: HealthTap Ebola Townhall - Ebola News and Update

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