Health Services Research SIGOctober 2010 – September 2011

• Newly established SIG (no previous WHI focus on health services research or claims data)

• About 45 members initially expressed interest, about 4-5 new members joined

• Monthly calls are attended by about 10-20 core members• 3 working groups established to focus on more specific

topics, also meet monthly: – Cardiovascular disease & diabetes– Cancer– Bone/Joint/Immunology

• Small group dedicated to implementation issues (Project Office, SIG chair, SIG co-chair, OAC Chair and CCC), meets 1-2x per month

Initial Focus of SIG• Bringing together researchers with knowledge of

WHI’s more traditional lines of research and researchers with health services research background/ CMS experience

• Clarifying data sources and availability (updating data to 2010 and Part D requests in process)

• Training of WHI statistical analysts to work with CMS data

• Establishing procedures and timeline for analytical access to data from outside CCC that protects WHI participants’ privacy (data enclave)

Manuscripts using CMS data Approved by P&P

• Effects of hormone therapy on incidence of atrial fibrillation in WHI Hormone Trials

• Risk factors for atrial fibrillation in WHI OS• Agreement of diabetes self-report compared with medical records and

CMS claims• Identifying rheumatoid arthritis and systemic lupus erythematosus

using medicare claims• Breast cancer recurrence: estimates from the linked WHI-Medicare

data• Agreement between CHD events based on Medicare claims data and

CHD events adjudicated by WHI—Mark Hlatky• Agreement between stroke based on Medicare claims data and stroke

adjudicated by WHI—Kamakshi Lakshminarayan • Assessment of Bias in WHI-Medicare Studies Limited to Fee-For-

Service Enrollees—Liz Haberman

Manuscripts using CMS data under development

• Continuity of care for patients with CVD and related risk factors in

the WHI• Patterns of colorectal cancer screening in WHI• Diabetes and prognosis of breast cancer, colorectal cancer and lung

cancer• Agreement between VTE based on Medicare claims data and VTE

adjudicated by WHI• Agreement between PVD based on Medicare claims data and PVD

adjudicated by WHI• Agreement between heart failure based on Medicare claims data

and HF adjudicated by WHI• Atrial Fibrillation and Magnesium Intake in WHI—Lisa Martin