h-s
DESCRIPTION
Full length EGFR promoter. -19. -153. Truncated EGFR promoter. N-S. Luciferase. H-S. Luciferase. - PowerPoint PPT PresentationTRANSCRIPT
H-SLuciferase
-1109 -19
N-SLuciferase-19-153
Full length EGFR promoter
1 303 588 671
1 303 588
1 303 588 671
303 588 671
wt
DDD
DID
DKD
Kinase domain Intermediate domain Death domain
Kinase domain
Kinase domain
Intermediate domain
Intermediate domain
Death domain
Death domain
RIP1 deletion mutants
Schematic diagram of full length and truncated EGFR promoters linked to firefly luciferase gene. The numbers indicate the nucleotide positions of the EGFR promoter relative to translation start site (ATG+1)
Schematic diagram of RIP1 and its mutants. RIP1 consists of three domains, Kinase, Intermediate and Death. The numbers indicate the amino acid positions of the protein.
Truncated EGFR promoter
Supplementary Figure 3 Ramnarain et al.