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Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine Streutker, Heather Maughan, Stephen Rubino, Eduardo H. Moriyama, Julia K. Copeland, Anu Surendra, Sachin Kumar, Blerta Green, Kaoru Geddes, Rossanna C. Pezo, William W. Navarre, Michael Milosevic, Brian C. Wilson, Stephen E. Girardin, Thomas M.S. Wolever, Winfried Edelmann, David S. Guttman, Dana J. Philpott, Alberto Martin Cell Volume 158, Issue 2, Pages 288-299 (July 2014) DOI: 10.1016/j.cell.2014.04.051 Copyright © 2014 Elsevier Inc. Terms and Conditions

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Page 1: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells 

Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine Streutker, Heather Maughan, Stephen Rubino, Eduardo H. Moriyama, Julia K. Copeland, Anu Surendra, Sachin Kumar, Blerta Green, Kaoru Geddes, Rossanna C. Pezo, William W. Navarre,

Michael Milosevic, Brian C. Wilson, Stephen E. Girardin, Thomas M.S. Wolever, Winfried Edelmann, David S. Guttman, Dana J. Philpott, Alberto Martin 

Cell Volume 158, Issue 2, Pages 288-299 (July 2014)

DOI: 10.1016/j.cell.2014.04.051

Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 1

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 2

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 3

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 4

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 6: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 5

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 7: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 6

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 8: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure 7

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 9: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S1

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 10: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S2

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 11: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S3

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 12: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S4

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 13: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S5

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 14: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S6

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 15: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Figure S7

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 16: Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells Antoaneta Belcheva, Thergiory Irrazabal, Susan J. Robertson, Catherine

Cell 2014 158, 288-299DOI: (10.1016/j.cell.2014.04.051) Copyright © 2014 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

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