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    MSTER INTERUNIVERSITARIO ENSALUD PBLICA

    Gua docente de la asignatura:

    Advanced Epidemiology

    Departamento de Ciencias Experimentales y de la Salud

    UNIVERSITAT POMPEU FABRA - UNIVERSITAT AUTNOMA DEBARCELONA

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    To be able to:

    - study the frequency and distribution of diseases within human populations and

    environments- determine if any factor is associated with the health effect

    - compare groups of people who are alike except for the risk factor under evaluation

    GENERAL

    Instrumental skills: Basic understanding of the design of epidemiological studies. Basic understanding of the analysis and interpretation of epidemiological research in

    public health. Ability to solve problems and compare and contrast epidemiological hypotheses.

    Personal skills: Ability to work a team. Ability to collate results, write their description and interpretation and orally defend.

    Communication skills. Methodological skills:

    Promote the ability to design studies following straightforward procedures. Promote the ability to analyse data from the epidemiological perspective as well as

    using statistical criteria. Encourage critical reading of epidemiological literature. Encourage self motivation in work.

    SPECIFIC

    Design of cross-sectional studies; assuring external validity. Design of longitudinal studies. Design of case-control studies; choosing the control

    group. Ability to analyse case-control and longitudinal studies. Working in teams to solve practical exercises.

    TEACHING AIMS

    TEACHING SKILLS

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    The work schedule is as follows:

    Theory: 9 hours

    Seminars: 13 hours

    Tutorials with professor: 8.4 hours

    Group work outside class: 9 hours

    Individual work (exercises and readings): 9 hours

    Individual study: 24 hours

    Evaluation: 3.6 hours (exam)

    Theory : explanation by the professor, with the use of examples, of theoretical concepts.

    Seminars : The work is to be done both individually and in groups of students (number to be

    fixed throughout the course).

    Group work outside class : Completing exercises. Discussion among classmates in order to

    answer the exercises is the basis for learning.

    Readings : of theoretical material to be able to follow the classes and fulfil the exercises.

    Continuous evaluation will be performed along the seminars, corrections and final exam.

    What is to be evaluated?

    The understanding of the problem, the application of adequate methods, the correct interpretation

    of results, the writing up of the work and the level of communicative ability demonstrated therein.

    Also the active participation in group work discussion and class. These are the items that will be

    evaluated.

    Each of the 6 seminars (individual exercises and discussions of papers by groups) will count 10%

    of the total grade, with a total of 60%. The final exam will count 40%. However, it is necessary to

    pass the exam (5 or above) in order to consider that 40% at the global evaluation.

    EVALUATION

    METHODOLOGY

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    January

    11/01/12 15:00 17:00 Introduction to the course. Seminar 1 Exercise Basic Epidemiology

    17:30 19:30 T. Session 1: Cross-sectional studies

    18/01/12 15:00 17:00 T. Session 2: Cohort studies

    17:30 19:30 Seminar 2: Discussion of paper 2 on longitudinal studies

    25/01/12 15:00 19:30 T. Session 3: and Seminar 3: Case-control studies

    February

    01/02/12 15:00 17:00 Seminar 4: Clinical trials

    17:30 19:30 T. Session 4: Confounding: definition and control

    08/02/12 15:00 17:00 T. Session 5: Evaluation of interaction17:30 19:30 Seminar 5: Exercises on confounding and interaction

    15/02/12 15:00 17:00 Seminar 6: Measures to assess test results

    (To be determined) Tutorial

    CALENDAR

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    Session and

    Teacher Title Readings and Tasks

    11/01/2012

    (OG) Introduction to the course.

    Seminar 1

    (1h)

    (OG)

    Exercise on

    basic

    Epidemiology

    Exercise on basic concepts on study design and measures

    Do the exercise individually and hand in it at the end of the session.

    (10% of the total grade)

    T. Session 1

    (2h)

    (OG)

    Cross-

    sectional

    studies

    Reading ( previous to session ):

    - Szklo & Nieto. Epidemiology: Beyond de Basics. Jones And

    Bartlett Publishers, 2006. Chapter 1: Basic study designs in

    analytical epidemiology

    - Rothman KJ, Greenland S. Modern epidemiology. 2nd edition.

    Boston: Little, Brown & Co., 1998. Chapter 5: Types of

    epidemiological studies.

    18/01/2012

    T.Session 2

    (2h)

    (OG)

    Cohort studies

    Reading ( previous to session ):

    - Rothman and Greenland: Chapter 6, pages 79-92.

    Other readings:

    - Clayton D, Hills M. Statistical methods in epidemiology. Oxford:

    Oxford Sciences Publications, 1993:227-233; 298-305

    Seminar 2

    (2h)

    (OG)

    Discussion of

    paper on

    longitudinal

    studies

    Paper for discussion:

    - Doll R, Peto R. Mortality in relation to smoking: 40 years

    observations on male British doctors. B Med J 1994; 308:901-11.

    * Group work.

    Time for conducting and handing in the exercise to bedetermined

    SESSIONS PROGRAMME

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    (10% of the total grade)

    21/01/2012

    T. Session 3

    (1h)

    (JB)

    Case-control

    studies

    Reading ( previous to session ):

    - Szklo & Nieto. Chapter 1: pages 28-51

    - Rothman and Greenland: Chapter 7, pages 93-114.

    Other readings:

    - Hosmer DW, Lemeshow S. Applied logistic regression. New

    York: John Wiley & sons, 1989; 1-36

    - Slechelman JJ. Case-control studies. Design, conduct, analysis.

    Oxford University Press 1982; 124-134; 227-280

    Seminar 2

    (3h)

    (JB)

    Discussion of

    papers on

    case-control

    Papers for discussion:

    - Bellido-Blasco JB, Celades-Porcar ME, Tirado-Balaguer MD, et

    al. Estudio de la Diarrea Infecciosa en Castelln (EDICS):

    incidencia poblacional del casos espordicos en 2004 y

    comparacin con el ao 2000. Med Clin 2006;127:448-50.

    - Bellido-Blasco JB, Gonzlez-Cano JM, Galiano-Arlandis JV, et

    al. Grupo EDICS Factores de riesgo de los casos espordicos de

    diarrea por Campylobacter, Salmonella y rotavirus en nios

    preescolares An Pediatr 2007;66:367-74.

    - Bellido-Blasco JB, Tirado-Balaguer MD, Gil-Fortuo M et al.

    Brote de infeccin alimentaria por Salmonella serotipo Mbandaka.

    Med Clin 2006;127:435-6

    - Bellido-Blasco JB, et al. A case-case study: rotavirus

    vaccination effectiveness in Castelln (Spain). Results using data

    from a specific diarrhoea study and the regional vaccine registry.

    28th Annual Meeting of the European Society for Paediatric

    Infectious Diseases (ESPID) Nice, France, May 4-8, 2010 .

    Group work.

    Time for conducting and handing in the exercise to be

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    - Rothman KJ. Epidemiology. An introduction. New York: Oxford University Press; 2002.

    - Rothman KJ, Greenland S. Modern epidemiology. 2nd edition. Boston: Little, Brown & Co., 1998- Szklo M, Nieto J. Epidemiology: Beyond de Basics. Jones And Bartlett Publishers, 2006.

    FUENTES DE INFORMACIN Y RECURSOS DIDCTICOS