<C.Cameco

August 17, 2012

Mr. John Passehl, P.G.UIC/GPCWater Quality DivisionWyoming Department of Environmental EqualityHerschler Building122 West 2 5th StreetCheyenne, WY 82002

CAMECO RESOURCESSmith Ranch-HighlandOperationMail:P.O. Box 1210Glenrock, WVY82637 USA

Tel: (307) 358-6541Fax: (307) 358-4533www. cameco. corn

CERTIFIED MAIL # 7011 0470 0001 0202 2337 RETURN RECEIPT REQUESTED

Re: Groundwater Restoration Research Proposal, LQD TFN 5 1/330, Cameco Resources,Permit 633

Dear Mr. Passehb:

Power Resources, Inc. d/b/a Cameco Resources (Cameco) is providing a proposal to conductthree (3) groundwater research study projects funded by the Wyoming Legislature to the WaterQuality Division (WQD) as requested by the Land Quality Division (LQD) Assistant Supervisor,Pam Rothwell. The proposal was submitted to the LQD on May 25, 2012 for review andpermission to conduct the research projects. LQD provided 58 comments on the proposedprojects and required Cameco to provide WQD a copy of the proposal application for evaluationof the use of chemicals as aquifer tracers. LQD suggests that further evaluation by theEnvironmental Protection Agency (EPA) may be necessary. Responses from Cameco to each ofthe proposed study projects submitted to LQD will be copied to the WQD.

Please contact me at 307-358-6541, ext. 476 or email to Kenneth Garoutte@cameco.com if youhave any questions.

Respectfully,

Ken GaroutteSafety, Health, Environment, Quality (SHEQ) Manager

KG/kg

Attachments: Proposal to Conduct Restoration Research Projects

NUCLEAR. The Clean Air Energy.

Cc: File SR 4.3.3.1Lowell Spackman, LQD, cover letter only: CERTIFIED MAIL # 7011 0470 0001 0202 2351Mr. Doug Mandeville, NRC Certified Mail # 7011 0470 0001 0202 0661Document Control Desk, NRC Certified Mail # 7011 0470 0001 0202 0722--'•

Ec: Cameco - Cheyenne

NUCLEAR. The Clean Air Energy.

TO: WDEQ

FROM: Jim Clay

SUBJECT: PROPOSAL TO CONDUCT RESTORATION RESEARCH PROJECTS

INTRODUCTION

This letter is a formal request for permission to conduct three field research experimentsfor the evaluation of promising techniques that may improve restoration methods atSmith Ranch and in the in situ recovery (ISR) mining industry in general. The specificexperiments are: 1) tracer tests to determine the hydrologic pathways between injectorand recovery wells; 2) bio-stimulation tests to determine the viability of using naturally-occurring bacteria to re-precipitate uranium and other redox-sensitive species; and 3)natural attenuation tests to determine the ability of the aquifer down gradient of themining zone to immobilize contaminants These tightly controlled experiments would beconducted on an extremely small scale and if successful would provide supporting datafor a request to alter the allowed permit restoration methods. It is important to emphasizethat no alteration in mine restoration methods or schedules as currently described in ourpermits would be done without regulatory approval.

Tracer studies to elucidate the flow patterns between injector and producer wells wouldaddress questions concerning hydrologic sweep efficiency during restoration. Theoptimization of sweep offers much promise for improving all restoration processesirrespective of whether they employ bio-stimulation, ground water sweep, reverseosmosis treatment, or the addition of inorganic chemical reductants such as sodiumsulfide. A bio-stimulation project was conducted at Smith Ranch from April toNovember of 2009. An analysis of the data resulting from that project concluded thathydrologic sweep was a major factor in limiting the efficacy of the bio-stimulation. Toour knowledge, there are no tracer studies in the scientific or public record that examinethe issue of injector/producer well flow patterns during restoration at an ISR mine.

In recent years, the scientific literature has contained many reports on the restoration ofground water containing uranium and other heavy metals. Contaminated ground waterand solids at Department of Energy (DOE) test sites at Oak Ridge, Tennessee; Hanford,Washington; and Rifle, Colorado have been treated with organic nutrients in an effort tostimulate the growth of native bacteria that can precipitate uranium and other heavymetals. 1-4 We know of no such studies at an ISR mine.

The natural attenuation of radioisotope contamination (including uranium) has beeninvestigated at the Savannah River, South Carolina DOE facility and appears to beproceeding on a time scale of decades.5 We are not aware of any data that sheds light onthe time-scale of natural attenuation processes in the aftermath of ISR mining inWyoming as well as the mobility of various ions in the aquifer.

Systematic investigations at Smith Ranch might identify improvements in the restorationprocess here that could decrease the required time to restore and minimize theconsumptive use of water (i.e., water that must be sent to disposal). The DOE studiescited in the preceding paragraphs involve ground water that often has radically differentgeochemistry from that encountered in the ISR mining industry. Furthermore, ISRaquifers are often considerably deeper below the surface of the ground and therefore lesssusceptible to periodic oxygen contamination from an influx of surface water orprecipitation.

PROPOSED PROJECT DESCRIPTIONS

Descriptions of each of the three projects follow. While there are obviously inter-relationships between them, it is hoped that each will be treated as a separate proposal bythe DEQ. Separate approval processes might allow work to begin on one or moreprojects while allowing the DEQ to further consider others.

Study #1, tracer studies:

Understanding the flow patterns between injector and recovery wells is a central issue inthe restoration process. This study would involve the use of a different tracer for eachinjector well in a pattern, so that the degree of hydrologic connection between individualinjectors and the producer is quantified. The tracers would be used to study the same twopatterns in header house 4-6 (centered on recovery wells 4P-121 and 4P-113) that arediscussed in the bio-stimulation narrative (study #2) below.

It is anticipated that about 5 kilograms of each of up to six tracers would be required for atest in a given pattern, and tracers tests would be run before bio-stimulation and(possibly) after bio-stimulation on at least one of the two patterns (and possibly both).Laboratory studies using core and ground water samples taken from the pattern centeredon 4P-121 will be conducted at Los Alamos National Laboratory (LANL) to identifytracer molecules that would not interact appreciably with the aquifer solids. There arethree families of molecules from which the tracers would be chosen: 1) fluorinatedbenzoates, 2) naphthalene sulfonates and 3) halides (bromide or iodide). The fluorinatedbenzoates and halides have been used to study a number of water sources of economicsignificance, including an aquifer in southern Nevada that has significant commercial andresidential importance. 6-7 For the case of that aquifer, they were used as part of theYucca Mountain Site Characterization Project. Given the arid nature of Nevada and thatstate's contentious relationship with the Department of Energy, it is noteworthy that theuse of these tracers was never challenged. Naphthalene sulfonates have also been used inpotable water sources for many years and are known to have low toxicities. Includedwith this submission are sample Material Safety Data Sheets for fluorinated benzoates,naphthalene sulfonates, sodium iodide and sodium bromide.

It would be informative to conduct a tracer test in a Mine Unit before mining begins.Such tests could be used in conjunction with core studies to examine the influence that

changes in mineralogy that accompany production and restoration have on flow patterns.These tests would be done by Dr. Paul Reimus of LANL.

Study #2, bio-stimulation:

The bio-stimulation efforts reported in the scientific literature have had varying degreesof success, but all have been conducted in environments unlike that encountered at anISR uranium mine. A key difference between the ISR case and the bio-stimulationefforts at DOE sites is the depth of the contaminated water. At the DOE sites,contaminated waters are much closer to the ground surface than is the case at ISR mines.ISR aquifers should be easier to sequester from atmospheric oxygen and might thereforebe more amenable to restoration using bio-stimulation techniques than is the case forshallower waters.

The proposed bio-stimulation study would be done on two patterns in header house 4-6(see the attached map). These are not contiguous and would encompass recovery wells4P-121 and 4P-1 13 and their associated injectors (41-213/214/217/218 for the case of 4P-121 and 41-201/202/206/207 for 4P-1 13). The patterns would be run sequentially so thatonly one pattern would be on at any given time to avoid the intermixing of water betweenthem. A line would be installed connecting the production manifold in the header houseto the injection manifold so that the production stream would re-circulate back to theinjectors. Note that re-circulating the stream between a recovery well and injectors hasbeen done on several occasions in the past without incident. Re-circulation ensures thatoxygen contamination is kept to a minimum since the recovery fluids are no longer beingsent to a satellite plant where storage in surface tanks can expose them to the atmosphere.Because this project is operating on such a small scale (the two patterns used for bio-stimulation encompass only about 20,000 square feet of surface area), a small peristalticpump would be used to precisely meter nutrient into the injectors.

The choice and quantity of organic nutrient used would be determined in consultationwith experts such as Drs. John Willford and Peter Stahl of the University of Wyomingand Dr. Kate Campbell of the United States Geological Survey (USGS). A core wastaken approximately mid-way between in 41-218 and 4P-121 (see the attached mapreferenced in the preceding paragraph), and samples of it along with the ground waterhave been sent to the University of Wyoming for microcosm testing. We anticipatepreliminary results from this testing in early to mid-June. The hole from whence the corewas taken has been cased and would be used as a passive sampling point if this proposalis approved. Please note that this well is covered by surety bond and was approved bythe state engineer's office.

Previous studies done by a Cameco Resources (CR) contractor have shown that organicamendments containing a mixture of safflower oil and ethanol or cheese whey aloneresult in rapid reductions of uranium concentrations (as well as selenium and arsenic) inground water. However, field studies at Smith Ranch using these nutrients resulted inclogged wells. The selection of organic nutrient for this project will be informed by thatexperience.

The flow from each individual injector will be measured, as will the pressure in theheader house injection manifold. A down hole sensor will be used to monitor pH,Oxidation-Reduction Potential (ORP), and conductivity. The readings for theseparameters will be logged and stored at periodic intervals. Samples will be drawn on aregular schedule for the determination of concentrations of such chemical species asdissolved uranium, total alkalinity, chloride, dissolved and total iron, selenium, andarsenic. The data should provide a detailed picture of the chemical evolution of the bio-stimulated volume of aquifer.

In addition to the field work, laboratory studies of the core will be undertaken tocharacterize the post-mining mineralization of the aquifer solids. There are many pre-mining core samples available in the Smith Ranch core library, and the mineralization ofthese can be compared to that in the post-mining 4P-121 solids. Mineralization will bestudied by a contingent of researchers that will include Dr. Reimus, Dr. Tanya Gallegosof the USGS, Cameco scientists at the company's Port Hope, Ontario research centre, andthe Universities of Wyoming and California at Berkeley (working through or with Dr.Reimus). The taking of a post bio-stimulation core is also planned so that changes inmineralization caused by biological activity can be observed.

An attempt will be made to characterize the bacterial populations present in the post-mining core material. Dr. Campbell will study DNA markers and Dr. Willford willexamine Phospholipid-derived fatty acids obtained from the core. The hope here is toshed light on which bacterial species at Smith Ranch might act to precipitate uranium andother heavy metals. Dr. Kevin Chamberlain and co-workers at the University ofWyoming will study U 2 3 8/U 2 35 and C 13/C12 isotope ratios in water samples to look forclues as to whether these ratios are changed via the metabolic pathways of micro-organisms within the restoration zone. They will also look at these isotopic ratios inwater samples taken from the natural attenuation study.

Study #3, natural attenuation and contaminant mobility:

This project would involve the introduction of lixiviate obtained from a previously minedbut not yet restored aquifer into a recovery well such as Mine Unit K North. Note thatthe lixiviate injection would be into a mine unit already approved for mining.Approximately 2000 gallons of lixiviate would be spiked with 0.5 to 1.0 kg of aconservative dilution marker such as sodium bromide, sodium iodide, or possibly afluorinated benzoate (see the discussion of study 1 above for information on thesecompounds). The lixiviate would then be sparged with nitrogen gas to remove oxygenbefore being sent down the recovery well. Prior to injection of the 2000 gallons, up to10,000 gallons of water will be withdrawn from the production well and stored on thesurface in a tank. After the 2000 gallons is injected, the larger volume of stored water(also sparged to remove dissolved oxygen) will be injected to push or chase the lixiviateout into the aquifer away from the production borehole. The well will then be leftstagnant (no injection or pumping) for three to six weeks. After that, the well will bepumped to recover most of the lixiviate, and the concentrations of uranium, total

alkalinity, chloride, selenium, and arsenic will be monitored over time. It is anticipatedthat at least 50,000 to 60,000 gallons of water will have to be withdrawn from theproduction well to recover most of the lixiviate and to obtain a well-developedbreakthrough curve for each marker and uranium. However, it may take more pumping,particularly for the uranium. The produced water will either be re-injected into injectionwells that are sufficiently far from the production to not interfere with testing or sent todisposal.

CONCLUSION

It should be emphasized that these projects are not a request for a change in therestoration processes described in our permits. If approved, they would be part of aresearch effort that might someday result in a request for change in the restorationprocess at Smith Ranch.

A key feature of the proposed projects is the small area that would be used. The twopatterns in header house 4-6 that would be involved in the bio-stimulation effortconstitute less than 2% of Mine Unit 4 (two patterns out of 130 in the unit) and would bemonitored in real time for changes in flow rates or injection pressure that would signalthe onset of well clogging. The natural attenuation study would take place in an area thatis already approved for mining (Mine Unit K north) and is unlikely to have anydiscernable impact on mining or subsequent restoration activities. The tracer studies areof a standard variety that has been done in many places, and residual concentrations ofthe tracer compounds will be largely removed by subsequent reverse osmosis treatmentof the tracer-tagged waters.

It is our hope that the three studies described in this document can be treated as separateproposals so that regulatory decisions as to whether they can proceed can be made on anindividual basis. The summer and early autumn months offer obvious advantages forconducting field research, and allowing even a single study to proceed early (particularlytracer work) would be of great value. Research activities would begin immediately afterreceiving regulatory approval with bio-stimulation and natural attenuation studiesfollowing the tracer tests. Some aspects of the field work would end with the onset ofcold weather in the autumn, but sampling of the bio-stimulation patterns would continuewell into the winter.

The objective of these projects is to provide information that will allow us to improve theground water restoration process at Smith Ranch. Peer-reviewed scientific publicationsor other reports will provide a mechanism for the lessons learned from these projects tobe made widely available to regulators and other uranium miners. A portion of theresearch described here is being funded by a grant from the Wyoming legislature that isbeing administered by the School of Energy Resources at the University of Wyoming.Additional funding is being provided by the Departments of Energy and the Interior, andCR is providing logistical support and drilling services for the work as well as a $50,000grant to researchers at the University of Wyoming. The large component of state and

federal government funding for these projects strengthens their credibility, and theexpertise of these researchers offers regulators and miners alike a rare opportunity to lookfor ways to improve ground water restoration processes at an ISR mine in Wyoming.

Footnotes:

1. Wei-Min, W.; Carley, J.; Fienen, M.; Mehlhorn, T.; Lowe, K.; Nyman, J.; Luo, J.;Gentile, M.E.; Rajan, R.; Wagner, D.; Hickey, R.F.; Gu, B.; Watson, D.; Cirpka,O.A.; Kitanidis, P.K.; Jardine, P.M.; and Criddle, C.S., 2006. Pilot-Scale in SituBioremediation in a Highly Contaminated Aquifer. 1. Conditioning of aTreatment Zone Environmental Science & Technology, 40, 3978-3985.

2. Wei-Min, W.; Carley, J.; Gentry, T.; Ginder-Vogel, M.A.; Fienen, M.; Mehlhorn,T.; Yan, H.; Caroll, S.; Pace, M.N.; Nyman, J.; Luo, J.; Gentile, M.E.; Fields,M.W.; Hickey, R.F.; Gu, B.; Watson, D.; Cirpka, O.A.; Zhou, J.; Fendorf, S.;Kitanidis, P.; Jardine, P.M.; and Criddle, C.S., 2006. Pilot-Scale in SituBioremediation in a Highly Contaminated Aquifer. 2. Reduction of U(VI) andGeochemical Control of U(VI) Bioavailability Environmental Science &Technology, 40, 3986-3995.

3. N'Guessan, A.L.; Vrionis, H.A.; Resch, C.T.; Long, P.E.; Lovley, D.B., 2008.Sustained Removal of Uranium From Contaminated Groundwater FollowingStimulation of Dissimilatory Metal Reduction Environmental Science &Technology, 42, 2999-3004.

4. Mohanty, S.B.; Kollah, B.; Hedrick, D.B.; Peacock, A.D.; Kukkadapu, R.K.;Roden, E.E. 2008. Biogeochemical Processes In Ethanol Stimulated Uranium-contaminated Subsurface Sediments Environmental Science & Technology, 42,4384-4390.

5. Wan, J.; Tokunaga, T.K.; Dong, W.; Denham, M.E.; Hubbard, S.S. 2012.Persistent Source Influences on the Trailing Edge of a Groundwater Plume, andNatural Attenuation Timeframes: The F-Area Savannah River Site EnvironmentalScience & Technology, 46, 4490-4497.

6. Hu, Q. and Moran, J.E. 2005. Simultaneous analyses and applications of multiplefluorobenzoate and halide tracers in hydrologic studies, Hydrological Processes,19, 2671-2687.

7. Reimus, P.; Umari, M.J.; Roback, R.; Earle, J.; Darnell, J.; and Farnham, I. 2003c.Estimates of Ambient Ground-Water Velocity in the Alluvium South of YuccaMountain, Nye County, Nevada, from Single-Well Tracer Tests, Proceedings of

the Oth International High-Level Radioactive Waste Management Conference,American Nuclear Society, March 30-April 2, 2003, Las Vegas, NV, pp. 102-113.

41-187

41-186

A41-:

41-198

-40193

41-203

41-208

41-202

41-213

41-207 HEAI41-217

41-212

MS,41-223 d

9

-41-22241-225

41-224

MSDS:

SECTION 1. ---------- CHEMICAL IDENTIFICATION-----

Product #: 264296 Name: 2,4-DIFLUOROBENZOIC ACID, 98%MATERIAL SAFETY DATA SHEET, Valid 8/98-10/98

1001 West St. Paul Ave.Milwaukee, WI 53233 USAPhone: 414-273-3850

CATALOG #: 264296NAME: 2,4-DIFLUOROBENZOIC ACID, 98%

SECTION 2. ------ COMPOSITIONINFORMATION ON INGREDIENTS

CAS #: 1583-58-0MF: C7H4F202EC NO: 216-430-9

SECTION 3. ----------- HAZARDS IDENTIFICATION---------

LABEL PRECAUTIONARY STATEMENTSIRRITANTIRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OFWATER AND SEEK MEDICAL ADVICE.WEAR SUITABLE GLOVES AND EYE/FACE PROTECTION.

SECTION 4. ----------- FIRST-AID MEASURES---

IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OFWATER FOR AT LEAST 15 MINUTES.IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUSAMOUNTS OF WATER.IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIALRESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.CALL A PHYSICIAN.WASH CONTAMINATED CLOTHING BEFORE REUSE.

SECTION 5. ---------- FIRE FIGHTING MEASURES----------

EXTINGUISHING MEDIAWATER SPRAY.

CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.SPECIAL FIREFIGHTING PROCEDURES

WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TOPREVENT CONTACT WITH SKIN AND EYES.

UNUSUAL FIRE AND EXPLOSIONS HAZARDS

EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

SECTION 6. -------- ACCIDENTAL RELEASE MEASURES--------

WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVYRUBBER GLOVES.

SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.AVOID RAISING DUST.VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

SECTION 7. ----------- HANDLING AND STORAGE-------

REFER TO SECTION 8.

SECTION 8. ------ EXPOSURE CONTROLS/PERSONAL PROTECTION .

CHEMICAL SAFETY GOGGLES.RUBBER GLOVES.NIOSH/MSHA-APPROVED RESPIRATOR.

SAFETY SHOWER AND EYE BATH.MECHANICAL EXHAUST REQUIRED.AVOID CONTACT AND INHALATION.DO NOT GET IN EYES, ON SKIN, ON CLOTHING.WASH THOROUGHLY AFTER HANDLING.IRRITANT.KEEP TIGHTLY CLOSED.STORE IN A COOL DRY PLACE.

SECTION 9. ------- PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE AND ODOR

OFF-WHITE POWDERPHYSICAL PROPERTIES

MELTING POINT: 188 C TO 190 C

SECTION 10. --------- STABILITY AND REACTIVITY---

INCOMPATIBILITIESSTRONG OXIDIZING AGENTS

HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTSTOXIC FUMES OF:

CARBON MONOXIDE, CARBON DIOXIDEHYDROGEN FLUORIDE

SECTION 11 --------- TOXICOLOGICAL INFORMATION--------

ACUTE EFFECTSMAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.CAUSES EYE AND SKIN IRRITATION.MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPERRESPIRATORY TRACT.TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, ANDTOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.

SECTION 12. --------- ECOLOGICAL INFORMATION----

DATA NOT YET AVAILABLE.

SECTION 13. --------- DISPOSAL CONSIDERATIONS----

DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN ACHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

SECTION 14. ---------- TRANSPORT INFORMATION --------

CONTACT ALDRICH CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.

SECTION 15. --------- REGULATORY INFORMATION----

EUROPEAN INFORMATIONIRRITANTR 36/37/38IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.S 26IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OFWATER AND SEEK MEDICAL ADVICE.S 37/39WEAR SUITABLE GLOVES AND EYE/FACE PROTECTION.

SECTION 16. ---------- OTHER INFORMATION-----------

THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TOBE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,

FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLINGOR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE ORPACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.

© COPYRIGHT 1998 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,FLUKA CHEMIE AGLICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY

MSDS: PENTAFLUOROBENZOIC ACID

SECTION 1 CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

MDL INFORMATION SYSTEMS, INC.1281 Murfreesboro Road, Suite 300Nashville, TN 37217-24231-615-366-2000

EMERGENCY TELEPHONE NUMBER:1-800-424-9300 (NORTH AMERICA)1-703-527-3887 (INTERNATIONAL)

SUBSTANCE: PENTAFLUOROBENZOIC ACID

TRADE NAMES/SYNONYMS:BENZOIC ACID, PENTAFLUORO-; 2,3,4,5,6-PENTAFLUOROBENZOIC ACID;PERFLUOROBENZOIC ACID; C7HF502; 0HS62944; RTECS DH6195000

CHEMICAL FAMILY: carboxylic acids

CREATION DATE: Dec 28 1992REVISION DATE: Dec 09 1997

SECTION 2 COMPOSITION, INFORMATION ON INGREDIENTS

COMPONENT: PENTAFLUOROBENZOIC ACIDCAS NUMBER: 602-94-8EC NUMBER (EINECS): 210-026-6PERCENTAGE: 100.0

SECTION 3 HAZARDS IDENTIFICATION

NFPA RATINGS (SCALE 0-4): HEALTH=l FIRE=l

EC CLASSIFICATION (CALCULATED): Noclassification assigned.

REACTIVITY=0

EMERGENCY OVERVIEW:PHYSICAL FORM: crystalsMAJOR HEALTH HAZARDS: No significant target effects reported.PHYSICAL HAZARDS: Dust/air mixtures may ignite or explode.

POTENTIAL HEALTH EFFECTS:

INHALATION:SHORT TERM EXPOSURE: no information is availableLONG TERM EXPOSURE: no information is available

SKIN CONTACT:SHORT TERM EXPOSURE: irritationLONG TERM EXPOSURE: no information is available

EYE CONTACT:SHORT TERM EXPOSURE: irritationLONG TERM EXPOSURE: no information is available

INGESTION:SHORT TERM EXPOSURE: no information is availableLONG TERM EXPOSURE: no information is available

CARCINOGEN STATUS:OSHA: NNTP: NIARC: N

SECTION 4 FIRST AID MEASURES

INHALATION: Remove from exposure immediately. Use a bag valve mask orsimilar device to perform artificial respiration (rescue breathing) ifneeded. Get medical attention.

SKIN CONTACT: Remove contaminated clothing, jewelry, and shoes immediately.Wash with soap or mild detergent and large amounts of water until noevidence of chemical remains (at least 15-20 minutes). Get medicalattention, if needed.

EYE CONTACT: Wash eyes immediately with large amounts of water or normalsaline, occasionally lifting upper and lower lids, until no evidence ofchemical remains. Get medical attention immediately.

INGESTION: If vomiting occurs, keep head lower than hips to help preventaspiration. Get medical attention, if needed.

SECTION 5 FIRE FIGHTING MEASURES

FIRE AND EXPLOSION HAZARDS: Slight fire hazard. Dust/air mixtures may igniteor explode.

EXTINGUISHING MEDIA: regular dry chemical, carbon dioxide, water, regularfoam

Large fires: Use regular foam or flood with fine water spray.

FIRE FIGHTING: Move container from fire area if it can be done without risk.Do not scatter spilled material with high-pressure water streams. Dike forlater disposal. Use extinguishing agents appropriate for surrounding fire.

Avoid inhalation of material or combustion by-products. Stay upwind andkeep out of low areas.

SECTION 6 ACCIDENTAL RELEASE MEASURES

OCCUPATIONAL RELEASE:Collect spilled material in appropriate container for disposal. Keep out ofwater supplies and sewers. Keep unnecessary people away, isolate hazard areaand deny entry.

SECTION 7 HANDLING AND STORAGE

Store and handle in accordance with all current regulations and standards.Store in a cool, dry place. Store in a tightly closed container. Keepseparated from incompatible substances.

SECTION 8 EXPOSURE CONTROLS. PERSONAL PROTECTION

EXPOSURE LIMITS:PENTAFLUOROBENZOIC ACID:

No occupational exposure limits established.

VENTILATION: Provide local exhaust ventilation system. Ventilation equipmentshould be explosion-resistant if explosive concentrations of material arepresent. Ensure compliance with applicable exposure limits.

EYE PROTECTION: Wear splash resistant safety goggles. Provide an emergencyeye wash fountain and quick drench shower in the immediate work area.

CLOTHING: Wear appropriate chemical resistant clothing.

GLOVES: Wear appropriate chemical resistant gloves.

RESPIRATOR: Under conditions of frequent use or heavy exposure, respiratoryprotection may be needed. Respiratory protection is ranked in order fromminimum to maximum. Consider warning properties before use.Any dust, mist, and fume respirator.Any air-purifying respirator with a high-efficiency particulate filter.Any powered, air-purifying respirator with a dust, mist, and fume filter.Any powered, air-purifying respirator with a high-efficiency particulate

filter.For Unknown Concentrations or Immediately Dangerous to Life or Health -

Any supplied-air respirator with full facepiece and operated in apressure-demand or other positive-pressure mode in combination with a

separate escape supply.Any self-contained breathing apparatus with a full facepiece.

SECTION 9 PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE: solidPHYSICAL FORM: crystalsODOR: Not availableMOLECULAR WEIGHT: 212.08MOLECULAR FORMULA: C6-F5-C-02-HBOILING POINT: 428 F (220 C)MELTING POINT: 212-216 F (100-102 C)VAPOR PRESSURE: Not applicableVAPOR DENSITY: Not applicableSPECIFIC GRAVITY: Not availableWATER SOLUBILITY: insolublePH: Not applicableVOLATILITY: Not applicableODOR THRESHOLD: Not availableEVAPORATION RATE: Not applicableCOEFFICIENT OF WATER/OIL DISTRIBUTION: Not available

SECTION 10 STABILITY AND REACTIVITY

REACTIVITY: Stable at normal temperatures and pressure.

CONDITIONS TO AVOID: Avoid heat, flames, sparks and other sources ofignition. Avoid contact with incompatible materials.

INCOMPATIBILITIES: oxidizing materials

PENTAFLUOROBENZOIC ACID:OXIDIZERS (STRONG): Fire and explosion hazard.

HAZARDOUS DECOMPOSITION:Thermal decomposition products: halogenated compounds, oxides of nitrogen,

carbon

POLYMERIZATION: Will not polymerize.

SECTION 11 TOXICOLOGICAL INFORMATION

PENTAFLUOROBENZOIC ACID:TOXICITY DATA:

178 mg/kg intraperitoneal-mouse LD50ACUTE TOXICITY LEVEL: Insufficient Data.

HEALTH EFFECTS:INHALATION:

ACUTE EXPOSURE:PENTAFLUOROBENZOIC

CHRONIC EXPOSURE:PENTAFLUOROBENZOIC

SKIN CONTACT:ACUTE EXPOSURE:

PENTAFLUOROBENZOIC

CHRONIC EXPOSURE:PENTAFLUOROBENZOIC

EYE CONTACT:ACUTE EXPOSURE:

PENTAFLUOROBENZOIC

CHRONIC EXPOSURE:PENTAFLUOROBENZOIC

INGESTION:ACUTE EXPOSURE:

PENTAFLUOROBENZOIC

CHRONIC EXPOSURE:PENTAFLUOROBENZOIC

ACID: No data available.

ACID: No data available.

ACID: May cause irritation.

ACID: No data available.

ACID: May cause irritation.

ACID: No data available.

ACID: No data available.

ACID: No data available.

SECTION 12 ECOLOGICAL INFORMATION

Not available

SECTION 13 DISPOSAL CONSIDERATIONS

Dispose in accordance with all applicable regulations.

SECTION 14 TRANSPORT INFORMATION

No classification assigned.

LAND TRANSPORT ADR/RID: No classification assigned.

AIR TRANSPORT IATA/ICAO: No classification assigned.

MARITIME TRANSPORT IMDG: No classification assigned.

SECTION 15 REGULATORY INFORMATION

U.S. REGULATIONS:TSCA INVENTORY STATUS: Y

TSCA 12(b) EXPORT NOTIFICATION: Not listed.CERCLA SECTION 103 (40CFR302.4): NSARA SECTION 302 (40CFR355.30): NSARA SECTION 304 (40CFR355.40): NSARA SECTION 313 (40CFR372.65): NSARA HAZARD CATEGORIES, SARA SECTIONS 311/312 (40CFR370.21):

ACUTE: NCHRONIC: NFIRE: NREACTIVE: N

SUDDEN RELEASE: NOSHA PROCESS SAFETY (29CFR1910.119): N

STATE REGULATIONS:California Proposition 65: N

EUROPEAN REGULATIONS:EC NUMBER (EINECS): 210-026-6

SECTION 16 OTHER INFORMATION

©COPYRIGHT 1984-1998 MDL INFORMATION SYSTEMS, INC. ALL RIGHTS RESERVED.

MSDS:

SECTION 1. --------- CHEMICAL IDENTIFICATION---------

Product #: D2027 Name: 2,6-DIFLUOROBENZOIC ACIDMATERIAL SAFETY DATA SHEET, Valid 8/98-10/98

P.O. Box 14508St. Louis, MO 63178 USAPhone: 314-771-5765

CATALOG #: D2027NAME: 2,6-DIFLUOROBENZOIC ACID

SECTION 2. ----- COMPOSITIONINFORMATION ON INGREDIENTS

CAS #: 385-00-2MF: C7H4F202EC NO: 206-856-3

SYNONYMS2,6-DIFLUOROBENZOIC ACID *

SECTION 3. --- HAZARDS IDENTIFICATION--

LABEL PRECAUTIONARY STATEMENTSHARMFULHARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OFWATER AND SEEK MEDICAL ADVICE.

WEAR SUITABLE PROTECTIVE CLOTHING AND GLOVES.

SECTION 4. ---------- FIRST-AID MEASURES----------

IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OFWATER FOR AT LEAST 15 MINUTES.IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUSAMOUNTS OF WATER.

IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIALRESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.CALL A PHYSICIAN.WASH CONTAMINATED CLOTHING BEFORE REUSE.

SECTION 5. --------- FIRE FIGHTING MEASURES---------

EXTINGUISHING MEDIAWATER SPRAY.CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.

SPECIAL FIREFIGHTING PROCEDURESWEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TOPREVENT CONTACT WITH SKIN AND EYES.

UNUSUAL FIRE AND EXPLOSIONS HAZARDSEMITS TOXIC FUMES UNDER FIRE CONDITIONS.

SECTION 6. -------- ACCIDENTAL RELEASE MEASURES

WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVYRUBBER GLOVES.SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.AVOID RAISING DUST.VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.

SECTION 7. ---------- HANDLING AND STORAGE-

REFER TO SECTION 8.

SECTION 8. ------ EXPOSURE CONTROLS/PERSONAL PROTECTION-

CHEMICAL SAFETY GOGGLES.RUBBER GLOVES.NIOSH/MSHA-APPROVED RESPIRATOR.SAFETY SHOWER AND EYE BATH.MECHANICAL EXHAUST REQUIRED.AVOID CONTACT AND INHALATION.DO NOT GET IN EYES, ON SKIN, ON CLOTHING.WASH THOROUGHLY AFTER HANDLING.

IRRITANT.HARMFUL SOLID.KEEP TIGHTLY CLOSED.STORE IN A COOL DRY PLACE.

SECTION 9. ----- PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE AND ODORWHITE FIBROUS POWDER

PHYSICAL PROPERTIESMELTING POINT: 158 C TO 160 C

SECTION 10. --------- STABILITY AND REACTIVITY-------

INCOMPATIBILITIESSTRONG OXIDIZING AGENTSSTRONG BASES

HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTSTOXIC FUMES OF:CARBON MONOXIDE, CARBON DIOXIDEHYDROGEN FLUORIDE

SECTION 11. --------- TOXICOLOGICAL INFORMATION

ACUTE EFFECTSMAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.

CAUSES EYE AND SKIN IRRITATION.MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPERRESPIRATORY TRACT.TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, ANDTOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.

RTECS #: DG8559000BENZOIC ACID, 2,6-DIFLUORO-

ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FORCOMPLETE INFORMATION.

SECTION 12. --------- ECOLOGICAL INFORMATION

DATA NOT YET AVAILABLE.

SECTION 13. --------- DISPOSAL CONSIDERATIONS-----

DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN ACHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

SECTION 14. ---------- TRANSPORT INFORMATION-----

CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.

SECTION 15. --------- REGULATORY INFORMATION-----

EUROPEAN INFORMATIONHARMFULR 20/21/22HARMFUL BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.

R 36/37/38IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.S 26IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OFWATER AND SEEK MEDICAL ADVICE.S 36/37WEAR SUITABLE PROTECTIVE CLOTHING AND GLOVES.

SECTION 16. ----------- OTHER INFORMATION------------

THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TOBE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLINGOR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE ORPACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.

© COPYRIGHT 1998 SIGMA CHEMICAL CO., ALDRICH CHEMICAL CO., INC.,FLUKA CHEMIE AGLICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY

MReactivity 0

Personal EProte ction

Material Safety Data SheetSodium bromide MSDS

Section 1: Chemical Product and Company Identification

Product Name: Sodium bromide

Catalog Codes: SLS3820, SLS1600

CAS#: 7647-15-6

RTECS: VZ3150000

TSCA: TSCA 8(b) inventory: Sodium bromide

CI#: Not available.

Synonym: Bromide salt of sodium

Chemical Name: Sodium Bromide

Chemical Formula: NaBr

Contact Information:Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396

US Sales: 1-800-901-7247International Sales: 1-281-441-4400

Order Online: ScienceLab.com

CHEMTREC (24HR Emergency Telephone), call:1-800-424-9300

International CHEMTREC, call: 1-703-527-3887

For non-emergency assistance, call: 1-281-441-4400

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

Sodium bromide 7647-15-6 100

Toxicological Data on Ingredients: Sodium bromide: ORAL (LD50): Acute: 3500 mg/kg [Rat]. 7000 mg/kg [Mouse].

Section 3: Hazards Identification

Potential Acute Health Effects:Hazardous in case of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant).

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition.

Section 4: First Aid Measures

Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention.

Skin Contact:

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Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold watermay be used.

Serious Skin Contact: Not available.

Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention.

Serious Inhalation: Not available.

Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Non-flammable.

Auto-Ignition Temperature: Not applicable.

Flash Points: Not applicable.

Flammable Limits: Not applicable.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Not applicable.

Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.

Fire Fighting Media and Instructions: Not applicable.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill:Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water onthe contaminated surface and dispose of according to local and regional authority requirements.

Large Spill:Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on thecontaminated surface and allow to evacuate through the sanitary system.

Section 7: Handling and Storage

Precautions:Do not ingest. Do not breathe dust. Avoid contact with eyes. Wear suitable protective clothing. In case of insufficientventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or thelabel. Keep away from incompatibles such as oxidizing agents, acids.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 25°C (77°F).

I Section 8: Exposure Controls/Personal Protection I

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Engineering Controls:Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommendedexposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminantsbelow the exposure limit.

Personal Protection:Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid.

Odor: Not available.

Taste: Not available.

Molecular Weight: 102.91 g/mole

Color: Not available.

pH (1% soln/water): 6.5-8.0

Boiling Point: 13900C (25340F)

Melting Point: 755 0C (1391 *F)

Critical Temperature: Not available.

Specific Gravity: 3.21 (Water = 1)

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

lonicity (in Water): Not available.

Dispersion Properties: See solubility in water, methanol.

Solubility:Easily soluble in cold water, hot water. Soluble in methanol. 1 g dissolves in 1.1 ml of water. 1 g dissolves in about 16 ml ofalcohol. 1 g dissolves in 6 ml of methanol

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Incompatible materials, moisture

Incompatibility with various substances: Reactive with oxidizing agents, acids.

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Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity:Absorbs moisture from the air but is not deliquescent. Hygroscopic. Also incompatible with alkaloidal and heavy metal salts,and Bromine Trifluoride.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 3500 mg/kg [Rat].

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans:Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans:May cause adverse reproductive effects (male and female effects on fertility and effects on newborns and fetotoxicity) basedon animal data Human: passes the placental barrier, detected in maternal milk.

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause mild skin irritation. Eyes: Causes eye irritation. Inhalation: May causerespiratory tract irritation. Ingestion: May cause gastrointestinal tract irritation with nausea and vomiting, abdominal pain,constipation. Bromide poisoning following acute ingestion is more rare and may affect the central nervous system (CNSdepression - somnolence, confusion, ataxia, coma and other symptoms similar to chronic ingestion), cardiovascular system(hypotension, tachycardia), kidneys (acute renal failure, urinary incontinence), and respiration (acute respiratory distresssyndrome). It may also cause eye disturbances such as mydriasis and nystagmus, disturbances of apparent color of objects,blurring or indistinctness of vision, apparent movement or wiggling and change in apparent size of objects, large pupils,subnormal reaction to light, diplopia, and photophobia. Chronic Potential Health Effects: Skin: Prolonged or repeated skincontact may cause skin rashes. Eyes: Prolonged or repeated eye contact may cause blepharitis, and conjunctivitis. Prolongedor repeated ingestion may cause skin rashes (bromoderma, acne, pyoderma gangrenosum, erythema multiforme), affect theliver, endocrine system (thyroid), metabolism(anorexia), blood, vision (visual disturbances, permanently decreased visionand may produce a toxic syndrome, "Bromism" which may be characterized by behavior/central nervous symptoms suchCNS depression, irritability, headache, confusion, slurred speech, memory loss, lethargy, ataxia, tremor, agitation, delusion,disoriented, paranoia, aggressiveness, hallucinations, mania, fatigue, seizure, neuropathy, muscle weakness, coma. Also, inindividuals with chronic bromism, the tongue may have a coated or furred appearance.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.

Special Remarks on the Products of Biodegradation: Not available.

I Section 13: Disposal Considerations

Waste Disposal: I

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I Waste must be disposed of in accordance with federal, state and local environmental control regulations. I

Section 14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: Sodium bromide

Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada): Not controlled under WHMIS (Canada).

DSCL (EEC):R36- Irritating to eyes. S2- Keep out of the reach of children. S24/25- Avoid contact with skin and eyes. S46- If swallowed,seek medical advice immediately and show this container or label.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0

Personal Protection: E

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 08:26 PM

Last Updated: 11/01/2010 12:00 PM

The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.

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Reactivity 0

Personal EProte ction

Material Safety Data SheetSodium iodide MSDS

Section 1: Chemical Product and Company Identification

Product Name: Sodium iodide

Catalog Codes: SLS1486, SLS2905

CAS#: 7681-82-5

RTECS: WB6475000

TSCA: TSCA 8(b) inventory: Sodium iodide

CI#: Not available.

Synonym:

Contact Information:Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396

US Sales: 1-800-901-7247International Sales: 1-281-441-4400Order Online: ScienceLab.com

CHEMTREC (24HR Emergency Telephone), call:1-800-424-9300

International CHEMTREC, call: 1-703-527-3887

For non-emergency assistance, call: 1-281-441-4400

Chemical Name: Not available.

Chemical Formula: Nal

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

Sodium iodide 7681-82-5 100

Toxicological Data on Ingredients: Sodium iodide: ORAL (LD50): Acute: 4340 mg/kg [Rat]. 1000 mg/kg [Mouse].

Section 3: Hazards Identification

Potential Acute Health Effects:Very hazardous in case of ingestion. Hazardous in case of eye contact (irritant), of inhalation. Slightly hazardous in case ofskin contact (irritant, permeator).

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to the nervous system. Repeated or prolonged exposureto the substance can produce target organs damage.

Section 4: First Aid Measures

Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Do not use an eye ointment. Seek medical attention.

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Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used.Cover the irritated skin with an emollient. If irritation persists, seek medical attention.

Serious Skin Contact: Not available.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Serious Inhalation: Not available.

Ingestion:Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication thatthe toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar,tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Non-flammable.

Auto-Ignition Temperature: Not applicable.

Flash Points: Not applicable.

Flammable Limits: Not applicable.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Not applicable.

Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.

Fire Fighting Media and Instructions: Not applicable.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill:Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water onthe contaminated surface and dispose of according to local and regional authority requirements.

Large Spill:Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on thecontaminated surface and allow to evacuate through the sanitary system.

Section 7: Handling and Storage

Precautions:Do not ingest. Do not breathe dust. Avoid contact with eyes Wear suitable protective clothing In case of insufficient ventilation,wear suitable respiratory equipment If ingested, seek medical advice immediately and show the container or the label. Keepaway from incompatibles such as oxidizing agents, metals, acids.

Storage:No specific storage is required. Use shelves or cabinets sturdy enough to bear the weight of the chemicals. Be sure that it isnot necessary to strain to reach materials, and that shelves are not overloaded.

p. 2

Section 8: Exposure Controls/Personal Protection

Engineering Controls:Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommendedexposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminantsbelow the exposure limit.

Personal Protection:Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid. (Deliquescent crystals solid.)

Odor: Odorless.

Taste: Bitter. Saline. (Strong.)

Molecular Weight: 149.89 g/mole

Color: White.

pH (1% soln/water): 7 [Neutral.]

Boiling Point: Decomposes.

Melting Point: 651'C (1203.8°F)

Critical Temperature: Not available.

Specific Gravity: 3.67 (Water = 1)

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

lonicity (in Water): Not available.

Dispersion Properties: See solubility in water, methanol, acetone.

Solubility:Easily soluble in cold water, hot water. Partially soluble in methanol, acetone.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances:

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Highly reactive with oxidizing agents, acids. Reactive with metals.

Corrosivity:Highly corrosive in presence of aluminum, of zinc, of copper. Corrosive in presence of steel. Non-corrosive in presence ofglass, of stainless steel(304), of stainless steel(316).

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: No.

Section 11: Toxicological Information

Routes of Entry: Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 1000 mg/kg [Mouse].

Chronic Effects on Humans: The substance is toxic to the nervous system.

Other Toxic Effects on Humans:Very hazardous in case of ingestion. Hazardous in case of inhalation. Slightly hazardous in case of skin contact (irritant,permeator).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: The products of degradation are more toxic.

Special Remarks on the Products of Biodegradation: Not available.

Section 14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: Sodium iodide

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Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada): Not controlled under WHMIS (Canada).

DSCL (EEC): R36- Irritating to eyes.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0

Personal Protection: E

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 08:27 PM

Last Updated: 11/01/2010 12:00 PM

The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab. com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab. comhas been advised of the possibility of such damages.

p. 5