gmd 411 lecture week5 31682

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    ByDr Tharwat Wagdy Hussien

    Ass.Prof.of Hematology & InternalMedicine

    Medical Academy

    By

    Dr Tharwat Wagdy Hussien

    Ass.Prof.of Hematology & InternalMedicine

    Medical Academy

    Heart Failure

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    What is Heart Failure? The heart is not pumping as well as it

    should

    Usually, the heart has been weakened byan underlying condition

    Blocked arteries

    Heart attack

    High blood pressure Infections

    Heart valve abnormalities

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    Heart failure can involve the left

    or right side of the heart or both

    Usually the left side is affectedfirst

    Heart failure occurs when either

    side of the heart cannot keep upwith the flow of blood.

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    What is Left Heart Failure? Involves the left ventricle (lower

    chamber) of the heart

    Systolic failure The heart looses its ability to contract

    or pump blood into the circulation

    Diastolic failure The heart looses its ability to relax

    because it becomes stiff

    Heart cannot fill properly between eachbeat

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    Systolic and diastolic heart

    failure are treated with different

    types of medications

    In both types, blood may back up

    in the lungs causing fluid to leak

    into the lungs (pulmonary edema)

    Fluid may also build up in tissues

    throughout the body (edema)

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    What is Right Heart Failure? Usually occurs as a result of left

    heart failure The right ventricle pumps blood to

    the lungs for oxygen

    Occasionally isolated right heart

    failure can occur due to lung

    disease or blood clots to the lung

    (pulmonary embolism)

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    What Causes Heart Failure? Health conditions that either damage

    the heart or make it work too hard:

    1-Coronary artery disease 2-Heart attack

    3-High blood pressure

    4-Abnormal heart valves 5-Heart muscle diseases

    (cardiomyopathy)

    6-Heart inflammation (myocarditis)

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    7- Congenital heart defects

    8- Severe lung disease

    9- Diabetes 10-Severe anemia

    11-Overactive thyroid gland

    (hyperthyroidism) 12-Abnormal heart rhythms

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    1-Coronary artery disease Cholesterol and fatty deposits build up

    in the hearts arteries Less blood and oxygen reach the heart

    muscle

    This causes the heart to work harderand occasionally damages the heart

    muscle

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    2-Heart attack An artery supplying blood to the heart

    becomes blocked

    Loss of oxygen and nutrients damages

    heart muscle tissue causing it to die Remaining healthy heart muscle must

    pump harder to keep up

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    3-High blood pressure Uncontrolled high blood pressure doubles a

    persons risk of developing heart failure

    Heart must pump harder to keep blood

    circulating

    Over time, chamber first thickens, then gets

    larger and weaker

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    4-Abnormal heart valves

    5-Heart muscle disease

    Damage to heart muscle due todrugs, alcohol or infections

    6-Congenital heart disease

    7-Severe lung disease

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    8-Diabetes

    Tend to have other conditions thatmake the heart work harder

    9-Obesity

    Hypertension High cholesterol

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    10-Severe anemia Not enough red blood cells to carry oxygen

    Heart beats faster and can become overtaxedwith the effort

    11-Hyperthyroidism Body metabolism is increased and overworks

    the heart

    12-Abnormal Heart Rhythm If the heart beats too fast, too slow or

    irregular it may not be able to pump enoughblood to the body

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    Signs and Symptoms of Heart Failure 1- Shortness of Breath (dyspnea)

    WHY?

    Blood backs up in the pulmonary veins because theheart cant keep up with the supply an fluid leaks into

    the lungs

    SYMPTOMS

    Dyspnea on exertion or at rest

    Difficulty breathing when lying flat

    Waking up short of breath

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    2-Persistent Cough or Wheezing

    WHY?

    Fluid backs up in the lungs

    SYMPTOMS

    Coughing that produces white or pink blood-tinged

    sputum

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    3-Edema

    WHY?

    Decreased blood flow out of the weak heart

    Blood returning to the heart from the veins backs

    up causing fluid to build up in tissues

    SYMPTOMS

    Swelling in feet, ankles, legs or abdomen Weight gain

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    4-Tiredness, fatigue

    WHY?

    Heart cant pump enough blood to meet needs of

    bodies tissues

    Body diverts blood away from less vital organs

    (muscles in limbs) and sends it to the heart and

    brain

    SYMPTOMS Constant tired feeling

    Difficulty with everyday activities

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    5- Lack of appetite/ Nausea

    WHY?

    The digestive system receives less blood causing

    problems with digestion

    SYMPTOMS

    Feeling of being full or sick to your stomach

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    6- Confusion/ Impaired thinking

    WHY?

    Changing levels of substances in the blood (

    sodium) can cause confusion SYMPTOMS

    Memory loss or feeling of disorientation

    Relative or caregiver may notice this first

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    7- Increased heart rate

    WHY?

    The heart beats faster to make up for the loss in

    pumping function

    SYMPTOMS

    Heart palpitations

    May feel like the heart is racing or throbbing

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    New York Heart Association (NYHA)

    Functional Classification

    Class % of

    patients

    Symptoms

    I 35% No symptoms or limitations in ordinary physical

    activity

    II 35% Mild symptoms and slight limitation during

    ordinary activity

    III 25% Marked limitation in activity even during minimal

    activity. Comfortable only at rest

    IV 5% Severe limitation. Experiences symptoms even at

    rest

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    Treatment Options

    The more common forms of heart failurecannot be cured, but can be treated

    Lifestyle changes

    Medications

    Surgery

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    I- Lifestyle changes 1- Stop smoking

    2- Loose weight

    3- Avoid alcohol

    4- Avoid or limit caffeine

    5- Eat a low-fat, low-sodium diet

    6- Exercise

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    7- Reduce stress

    8- Keep track of symptoms and weight

    and report any changes or concern tothe doctor

    9- Limit fluid intake

    10-See the doctor more frequently

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    II- Medications used to treat Heart

    Failure: 1-ACE Inhibitors

    Cornerstone of heart failure therapy

    Proven to slow the progression of heart

    failure Vasodilatorcause blood vessels to expand

    lowering blood pressure and the hearts work

    load

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    2- Diuretics (water pills)

    Prescribed for fluid build up, swelling or

    edema Cause kidneys to remove more sodium and

    water from the bloodstream

    Decreases workload of the heart and edema

    Fine balance removing too much fluid can

    strain kidneys or cause low blood pressure

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    3- Potassium

    Most diuretics remove potassium from the

    body Potassium pills compensate for the amount

    lost in the urine

    Potassium helps control heart rhythm and is

    essential for the normal work of the nervoussystem and muscles

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    4- Vasodilators

    Cause blood vessel walls to relax

    Occasionally used if patient cannottolerate ACE

    Decrease workload of the heart

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    5- Digitalis preparations

    Increases the force of the hearts

    contractions Relieves symptoms

    Slows heart rate and certain irregular

    heart beats

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    6- Beta-blockers Lower the heart rate and blood pressure

    Decrease the workload of the heart

    7- Anticoagulant (coumadin) Used in patients at risk for developing blood

    clots in the blood vessels, legs, lung andheart

    Used in irregular heart rhythms due to risk ofstroke

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    III- Surgery and other Medical

    Procedures Not often used in heart failure unless there is a

    correctable problem

    Coronary artery bypass

    Angioplasty

    Valve replacement Defibrillator implantation

    Heart transplantation

    Left ventricular assist device (LVAD)

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