gmd 411 lecture week5 31682
TRANSCRIPT
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ByDr Tharwat Wagdy Hussien
Ass.Prof.of Hematology & InternalMedicine
Medical Academy
By
Dr Tharwat Wagdy Hussien
Ass.Prof.of Hematology & InternalMedicine
Medical Academy
Heart Failure
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What is Heart Failure? The heart is not pumping as well as it
should
Usually, the heart has been weakened byan underlying condition
Blocked arteries
Heart attack
High blood pressure Infections
Heart valve abnormalities
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Heart failure can involve the left
or right side of the heart or both
Usually the left side is affectedfirst
Heart failure occurs when either
side of the heart cannot keep upwith the flow of blood.
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What is Left Heart Failure? Involves the left ventricle (lower
chamber) of the heart
Systolic failure The heart looses its ability to contract
or pump blood into the circulation
Diastolic failure The heart looses its ability to relax
because it becomes stiff
Heart cannot fill properly between eachbeat
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Systolic and diastolic heart
failure are treated with different
types of medications
In both types, blood may back up
in the lungs causing fluid to leak
into the lungs (pulmonary edema)
Fluid may also build up in tissues
throughout the body (edema)
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What is Right Heart Failure? Usually occurs as a result of left
heart failure The right ventricle pumps blood to
the lungs for oxygen
Occasionally isolated right heart
failure can occur due to lung
disease or blood clots to the lung
(pulmonary embolism)
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What Causes Heart Failure? Health conditions that either damage
the heart or make it work too hard:
1-Coronary artery disease 2-Heart attack
3-High blood pressure
4-Abnormal heart valves 5-Heart muscle diseases
(cardiomyopathy)
6-Heart inflammation (myocarditis)
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7- Congenital heart defects
8- Severe lung disease
9- Diabetes 10-Severe anemia
11-Overactive thyroid gland
(hyperthyroidism) 12-Abnormal heart rhythms
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1-Coronary artery disease Cholesterol and fatty deposits build up
in the hearts arteries Less blood and oxygen reach the heart
muscle
This causes the heart to work harderand occasionally damages the heart
muscle
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2-Heart attack An artery supplying blood to the heart
becomes blocked
Loss of oxygen and nutrients damages
heart muscle tissue causing it to die Remaining healthy heart muscle must
pump harder to keep up
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3-High blood pressure Uncontrolled high blood pressure doubles a
persons risk of developing heart failure
Heart must pump harder to keep blood
circulating
Over time, chamber first thickens, then gets
larger and weaker
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4-Abnormal heart valves
5-Heart muscle disease
Damage to heart muscle due todrugs, alcohol or infections
6-Congenital heart disease
7-Severe lung disease
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8-Diabetes
Tend to have other conditions thatmake the heart work harder
9-Obesity
Hypertension High cholesterol
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10-Severe anemia Not enough red blood cells to carry oxygen
Heart beats faster and can become overtaxedwith the effort
11-Hyperthyroidism Body metabolism is increased and overworks
the heart
12-Abnormal Heart Rhythm If the heart beats too fast, too slow or
irregular it may not be able to pump enoughblood to the body
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Signs and Symptoms of Heart Failure 1- Shortness of Breath (dyspnea)
WHY?
Blood backs up in the pulmonary veins because theheart cant keep up with the supply an fluid leaks into
the lungs
SYMPTOMS
Dyspnea on exertion or at rest
Difficulty breathing when lying flat
Waking up short of breath
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2-Persistent Cough or Wheezing
WHY?
Fluid backs up in the lungs
SYMPTOMS
Coughing that produces white or pink blood-tinged
sputum
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3-Edema
WHY?
Decreased blood flow out of the weak heart
Blood returning to the heart from the veins backs
up causing fluid to build up in tissues
SYMPTOMS
Swelling in feet, ankles, legs or abdomen Weight gain
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4-Tiredness, fatigue
WHY?
Heart cant pump enough blood to meet needs of
bodies tissues
Body diverts blood away from less vital organs
(muscles in limbs) and sends it to the heart and
brain
SYMPTOMS Constant tired feeling
Difficulty with everyday activities
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5- Lack of appetite/ Nausea
WHY?
The digestive system receives less blood causing
problems with digestion
SYMPTOMS
Feeling of being full or sick to your stomach
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6- Confusion/ Impaired thinking
WHY?
Changing levels of substances in the blood (
sodium) can cause confusion SYMPTOMS
Memory loss or feeling of disorientation
Relative or caregiver may notice this first
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7- Increased heart rate
WHY?
The heart beats faster to make up for the loss in
pumping function
SYMPTOMS
Heart palpitations
May feel like the heart is racing or throbbing
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New York Heart Association (NYHA)
Functional Classification
Class % of
patients
Symptoms
I 35% No symptoms or limitations in ordinary physical
activity
II 35% Mild symptoms and slight limitation during
ordinary activity
III 25% Marked limitation in activity even during minimal
activity. Comfortable only at rest
IV 5% Severe limitation. Experiences symptoms even at
rest
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Treatment Options
The more common forms of heart failurecannot be cured, but can be treated
Lifestyle changes
Medications
Surgery
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I- Lifestyle changes 1- Stop smoking
2- Loose weight
3- Avoid alcohol
4- Avoid or limit caffeine
5- Eat a low-fat, low-sodium diet
6- Exercise
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7- Reduce stress
8- Keep track of symptoms and weight
and report any changes or concern tothe doctor
9- Limit fluid intake
10-See the doctor more frequently
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II- Medications used to treat Heart
Failure: 1-ACE Inhibitors
Cornerstone of heart failure therapy
Proven to slow the progression of heart
failure Vasodilatorcause blood vessels to expand
lowering blood pressure and the hearts work
load
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2- Diuretics (water pills)
Prescribed for fluid build up, swelling or
edema Cause kidneys to remove more sodium and
water from the bloodstream
Decreases workload of the heart and edema
Fine balance removing too much fluid can
strain kidneys or cause low blood pressure
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3- Potassium
Most diuretics remove potassium from the
body Potassium pills compensate for the amount
lost in the urine
Potassium helps control heart rhythm and is
essential for the normal work of the nervoussystem and muscles
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4- Vasodilators
Cause blood vessel walls to relax
Occasionally used if patient cannottolerate ACE
Decrease workload of the heart
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5- Digitalis preparations
Increases the force of the hearts
contractions Relieves symptoms
Slows heart rate and certain irregular
heart beats
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6- Beta-blockers Lower the heart rate and blood pressure
Decrease the workload of the heart
7- Anticoagulant (coumadin) Used in patients at risk for developing blood
clots in the blood vessels, legs, lung andheart
Used in irregular heart rhythms due to risk ofstroke
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III- Surgery and other Medical
Procedures Not often used in heart failure unless there is a
correctable problem
Coronary artery bypass
Angioplasty
Valve replacement Defibrillator implantation
Heart transplantation
Left ventricular assist device (LVAD)
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