GLYCERENE

GLYCERENEReduces metabolic

problems, improves fertility and increases milk yield

Cost of Metabolic diseases Displaced abomasum £750 (Kingshay

2011) Ketosis £81 (Cornell University) Retained placenta £274 (Esslemont 1997) Metritis £220 (Georgia University) Poor fertility efficiency linked to

incidences of metabolic problems

Why do we have metabolic problems?

High genetic merit cows depleting reserves

Insufficient energy supply Rapid weight loss Fat mobilisation Suppression of the immune system

0 1 2 3 4 5 6 7 8 9 10 11 12

1 2 3 4 5Periods

Month

Freshening

Body StoresUsed for

Milk Production

Body StoresRegained for

Next Lactation

Dry PeriodRumenRehab

Nutrient and Milk Yield Relationships in the Lactation and Gestation Cycle

Dry Matter Intake

Milk Production

Body Weight

Measuring weight loss and fat mobilisation

Body condition – useful aid but poor system for pre calvers and fresh as damage done by the time noticed

High butterfat % in early lactation – a guide to an indication of problems

NEFA’s – fastest and scientifically accurate through blood testing

NEFA’s are Non-Esterified Fatty Acids – a measure of rapid weight loss

NEFA Thresholds Trial to link NEFA levels with severity of

metabolic problems (Cornell University, 2009)

2758 cows blood sampled 15 days pre partum and 15 days postpartum

Risk ratios calculated on NEFA levels – how likely an occurrence of metabolic disease

Cornell ResultsProblem NEFA

aboveRisk ratio

DA 0.72 9.7CK 0.57 5.0MET 0.36 17Any 3 0.57 4.4DA = displaced abomasum; CK = clinical ketosisMET = metritis; Any 3 = DA, CK or MET

How do we reduce NEFA’s? Increase dry matter intake both pre partum

and postpartum correct dry matter barrier space housing feed quality water management

Feed GLYCERENE

Condition Change Post Calving

Body score loss <0.5 0.5 – 1.0 >1.0

Days to ovulation 28 38 44

Conception rate to 1st service (%) 65 53 17

Trials R Kupczynski, Wroclaw, Poland, 2011

Body condition scoreGroup 1

week pre

1 week post

3 weeks post

Control 3.75 3.40 3.04Glycerine

3.78 3.51 3.26

Trials R Kupczynski, Wroclaw, Poland, 2011

Blood parametersGroup NEFA’s Pre

calvingNEFA’s post calving

Control 0.40 1.32Glycerine

0.30 1.02

Trials R Kupczynski, Wroclaw, Poland, 2011

Milk yield (litres/cow/day)Group Up to 56 days 56-70 daysControl 37.94 46.0Glycerine 39.17 52.0Difference

+1.23 +6.0

TrialsHippen 2004Post Calving NEFA’sControl 0.624Glycerine 0.496

Hippen 2011Post Calving NEFA’sControl 0.855Glycerine 0.458

Trials Y H Chung, Penn State University, 2007 Urine ketones lower with glycerine (6.8 vs 17.9) NEFA’s lower Milk yield same for 21 days, but at

42 days was 6 litres higher (52 litres vs. 46 litres)

“Cows receiving glycerine were in a better metabolic state than cows receiving no glycerine”

UK Trial WiltshireNEFA BHB Glucos

eBCS Pre Calving

BSC Post Calving

BCS Change

Control 1.20 1.60 3.00 3.4 2.5 -0.9Glycerene 0.80 1.05 3.55 3.3 3.0 -0.3Difference -0.40 -

0.55+0.55 -0.1 +0.5 +0.6

Average days Pre Calving: Control 10, Glycerene 6Average days Post Calving: Control 20, Glycerene 18Glycerene fed cows were under more stress from being closer to calving and post calving than the control.

Since using Glycerene, this herd has reduced metabolic problems by 80%

Summary Energy deficiency results in rapid weight

loss Best measurement by NEFA’s Metabolic diseases linked to poor fertility Metabolic diseases very costly Reducing NEFA’s reduces metabolic

problems

Glycerene reduces NEFA’s

More glycerine uses Dynamite (nitro glycerine) Skin moisturisers Antiseptic (mouth wash, cough medicine,

toothpaste) Moisturising agent for cereal bars, icing Kills harmful bacteria Preserves foods Sweetener

Glycerine in human food

What is GLYCERENE? Glycerine on a dry base – more even

mixing; easier to handle. Trials show the dry product more effective.

Unique treatment process – reduces up to 35% losses in the mouth and throat.

Palatable – tastes sweet Reduces moulds and heating – used in

mixes for keeping TMR cool

Financial BenefitsRef: Cornell University 2009

High NEFA cows gave 650kgs less milk High NEFA cows 14-18% less likely to conceive 650kgs milk = £162.00 (25p/litre) 14% = 50 days on calving index = £250/cow

TOTAL cost of £412/cow with high NEFA’s Glycerene fed 21days pre & 150 days post

calving costs £42/cow

Benefit of £370/cow

GLYCERENEBenefit of £370/Cow