git3 - small, large surgical pathology
TRANSCRIPT
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
1/165
Surgical Pathology & X-rays for
Medical Students2008
GIT-3Small intestine
Colon
Rectum & anal canal
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
2/165
GIT 32
Abnormal gas patterns
in plain X-ray abdomen
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
3/165
GIT 33
The intestinal tract of normal adults generally contains less than 200 cc of gas
Five gases make up greater than 99% of gas passed per rectum.These are N2 , O2 , CO2 , H2 , and CH4
There are three sources of intestinal gas
Air swallowing Bacterial production Diffusion from the blood
depends upon theposition of thepatient and the levelof anxiety of thepatient
Bedridden patients,for example, may be
unable to eructate swallowed air, thus allowing it to pass
distally into the GIT
Bacterial metabolism is thesource of hydrogen andmethane production
Certain foodstuffs, (e.g.beans)
deliver nonabsorbablecarbohydrates to the colonwhere bacterial metabolismproduces both hydrogen andmethane.
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
4/165
GIT 34
Normal plain X-ray film of the abdomen, demonstrating
soft tissue densities
Normal plain X-ray film of the abdomen demonstrating
the bowel gas pattern
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
5/165
GIT 35
The radiographic evaluation of intestinal gas should include the following points:
what segment ofbowel containsthe gas
Dimension of theair-filled gut
Most distal pointthe gas has
passed in theintestine
Identify gutmucosa outlinedby the gas
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
6/165
GIT 36
In the supine position:Gas normally accumulates in the anteriorly placed segments of intestine:
the distal stomach, transverse colon, and sigmoid colon.
Gas within the remainder of the colon, particularly the rectum, is not uncommon
The gas-filled gut that in the most superior portion of the abdomen on the supine film is usually the stomach
The transverse colon lies immediately inferior
Ascending and descending portions of the colon occupy the right and left lateral most portions of the abdominal cavity
Air in the sigmoid colon tends to occupy a lower mid-line position, but because of variations in the length of the sigmoid mesocolon may extend into the upper mid-abdomen as well
Rectal air occupies a mid-line pelvic position
Small intestinal gas tends to accumulate in the mid-abdomen, framed by the colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
7/165
GIT 37
Stomach : AlwaysSmall Bowel : Twoor three loops of non-distended
bowelNormal diameter = 2.5 cm = 1US quarter
Large Bowel : Inrectum or sigmoid
almost always
Gas instomach
Gas in a fewloops ofsmall bowel
Gas inrectum or
sigmoid
Normal Gas Pattern
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
8/165
GIT 38
Erect Abdomen
A few air in
small bowel
Alwaysair/fluid level
in stomach
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
9/165
GIT 39
The position of the bowel is helpful. Small bowel is central while colon isperipheral (frame)
The gas may outline the colonic haustra or intestinal plicae circulares.
Haustra tend to be two to three millimeters wide, and occur at centimeter intervals.
Plicae circulares are approximately one millimeter wide and occur at millimeter intervals.
Extension of either of these soft tissue lines across the entire width of the lumen is
not the only helpful point of distinction. The width of the lines, spacing, and locationof the bowel loop are felt to be more helpful
Occasionally the distinction between colon and small bowel cannot bedetermined and a contrast study is necessary
The distinction between colon and small bowel
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
10/165
GIT 310
Air is seen in non-dilated loops of smalland large bowel.
Small loops arecentrally located, andcolon is distributedperipherally like apicture frame.
Normal BowelGas Pattern :
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
11/165
GIT 311
Small bowel loops aredistributed centrally inthe abdomen andhave mucosal foldsthat cross the entirelumen of the bowel .These folds are calledvalvulae conniventes or plica circularis andare visible in gas-filled loops
Plain X-ray supine : Small intestinal obstruction
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
12/165
GIT 312
The colon gas patternis usually distributed likea picture frame aroundthe periphery of theabdomen.
Colonic loops containhaustrations which donot extend all the wayacross the lumen of thebowel
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
13/165
GIT 313
Large vs. Small Bowel
Large BowelPeripheral
Haustral markings don't
extend from wall to wallSmall Bowel
Central
Valvulae extend acrosslumen
Maximum diameter of 2"
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
14/165
GIT 314
This is a normal plainX-ray abdomen in thesupine position
In supine X-raysof the abdomenwe look for:
Free airAir-fluid levels
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
15/165
GIT 315
Abnormal Gas Patterns
Functional Ileus
Localized (Sentinel Loops)Generalized adynamic ileus
Mechanical Obstruction
SBOLBO
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
16/165
GIT 316
Plain X-ray Abdomen - Postoperative adynamic ileus
Multiple loops of minimally dilated small bowel with air fluid levels at differentlevels within the same loop of intestine on the upright (103-2) film. There is asmall amount of gas in the right colon
Supine Erect
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
17/165
GIT 317
Plain X-ray abdomen (erect position)
Multiple fluid levels
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
18/165
GIT 318
Plain X-ray abdomen (erect position)
Multiple fluid levels
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
19/165
GIT 319
Mechanical Small bowlobstruction (supine position)
Dilated small bowelFrequent audible intestinal sounds(Fighting loops)
Little gas in colon, especially rectumKey: disproportionate dilatation of SB
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
20/165
GIT 320
Plain X-ray- Small bowel obstruction secondary to adhesions
Supine
The supine view of the abdomendemonstrate dilated small bowel without
any air in the colon
Erect
Erect Film shows a large amount of fluidwithin the small bowel. There are multiplesmall pockets of air arranged in a line noted in theleft lower quadrant (residual colonic gas)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
21/165
GIT 321
Plain abdominalradiograph: Inverted U-shaped, gaseous, dilated
small bowel loops canbe observed above oneanother (arrows) in themiddle of the abdomen.The double arrow pointsto an air-fluid level in theintestines
Small intestinal illius
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
22/165
GIT 322
Mechanical SBO
Causes Adhesions
Hernia*
Volvulus
Gallstone ileus*
Intussusception
*Cause may be visible on plain film
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
23/165
GIT 323
Mechanical LBO
Key Features
Dilated colon to point of obstruction
Little or no air in rectum/sigmoidLittle or no gas in small bowel, if
Ileocecal valve remains competent
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
24/165
GIT 324
Mechanicallarge bowelobstruction
Dilated colon to point of obstructionLittle or no air in rectum/sigmoid(according to the site of obstruction)Little or no gas in small bowel, if Ileocecal valve remains competent
Tumor (CA colon)Volvulus (Sigmoid)Hernia (strangulated)IntussusceptionDiverticulitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
25/165
GIT 325
Sigmoid carcinoma causing colon obstruction
Supine Erect
Multiple dilated loops of bowel with scattered air fluid levels on the upright film. The caliber and locationof the bowel loops suggest that the air is within the colon. There is some small intestinal gas noted inthe right mid abdomen, but the preponderance of air is in the colon. There is little rectal gas present
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
26/165
GIT 326
Barium enema of the same patient
shows an abruptobstruction at thelevel of the
sigmoid colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
27/165
GIT 327
Large bowl obstruction
(supine position)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
28/165
GIT 328
History : Elderly man with newonset of abdominal painPhysical exam : distended,tympanitic abdomen
Diagnosis: SigmoidVolvulus
In sigmoid volulus, the colon
appears as a dilated,inverted U-shaped loop which extends from the pelvis into the mid-upper abdomen. (coffee bean sign)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
29/165
GIT 329
Sigmoid VolvulusMost common colonic volvulus
Water soluble enema confirms
distal obstructionIf discovered early,
colonoscopic decompression isusually effective
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
30/165
GIT 330
Volvulous of thesigmoid colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
31/165
GIT 331
Volvulous of thesigmoid colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
32/165
GIT 332
Generalizedadynamic ileus
Supine
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
33/165
GIT 333
Generalized Adynamic Ileus
Gas in dilated small bowel and large bowel to rectumLong air-fluid levelsOnly post-op patients have generalized ileus
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
34/165
GIT 334
Both mucosaland serosalsurfaces of
bowel wall areoutlined by gasindicating thatthere must befree gas in theperitonealcavity
Plain X-rayabdomen
Supine
Pneumoperitoneum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
35/165
GIT 335
Pneumoperitoneum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
36/165
GIT 336
Intestinal obstruction
Dynamic AdynamicPeristalsis is workingagainst mechanical
obstruction Absent peristalsis
Paralytic ileus
Nonpropulsive peristalsis
Mesenteric vascular occlusion
Intraluminal Impacted faeces
Foreign body
Intramural Malignant or inflammatory stricture
Extramural Peritoneal bands
Strangulated hernia
Volvulus,Intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
37/165
GIT 337
Dynamic obstruction
Abdominal pain Distension Vomiting Absolute constipation
Symptoms of intestinal obstruction
These symptoms will vary according to the site of obstruction
Clinical types of obstruction Small bowel obstruction Large bowel obstruction
High Low
Distension is early & markedPain is mild
Vomiting & dehydration arelate
Early profusevomiting (Rapiddehydration)
Minimal distension
Minimal fluid levels
in abdominal X-ray
Vomiting is delayedPain is predominant
with central distension
Multiple central fluid
levels in x-ray
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
38/165
GIT 338
The clinical picture of intestinal obstruction is also influenced by whether the presentation is:
Acute Chronic Acute onchronic
Subacute
Usually insmall bowel
obstructionSudden onset
of severecolicky centralabdominal pain
& distensionEarly vomiting
& constipation
Usually inlarge bowel
obstructionLower
abdominal colic& constipation
Followed bydistension
Short history of distension &
vomiting on topof backgroundof pain &constipation
Incompleteobstruction
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
39/165
GIT 339
Pathophysiology
Above obstruction Below obstructionObstruction
The bowel has normalperistalsis & absorption untilit becomes empty, then becomes immobile
Proximal peristalsis increases toovercome obstruction (increases intestinal sounds)
If obstruction is not relieved, the
bowel will dilate, peristalsis willdecrease
With more dilatation the bowelbecomes flaccid & paralyzed
Distension is due to :Gas produced by overgrowth of organisms
Fluid of digestive juices which is not absorbed
Dehydration & electrolyte loss are due to:Reduced oral intake
Defective intestinal absorption
Vomiting
Fluid sequestration in bowel lumen
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
40/165
GIT 340
Examples of dynamic obstruction
Extramural Peritoneal bands
Strangulated hernia
Volvulus,Intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
41/165
GIT 341
Peritoneal bands
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
42/165
GIT 342
Small bowel obstructionsecondary to intraperitonealfibrous band adhesion
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
43/165
GIT 343
Intestinal Obstruction Small Bowel Infarctionsecondary to intraperitoneal
fibrous band (Late presentation
irreversible intestinal ischemia)
The commonestcause of inrtaperitonealbands is previousinrtaperitonealoperation. e.g. : appendectomy,exploration,..
S ll b l b i
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
44/165
GIT 344
Central distension of small intestinal loops.
Note the metal clips of a previous operation
Small bowel obstruction
Erect :
Multiple fluid levels
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
45/165
GIT 345
Strangulated hernia
St g l t d f l h i i g
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
46/165
GIT 346
Strangulated femoral hernia causingintestinal obstruction
1
2
3
4
S ll i i l l i
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
47/165
GIT 347
Small intestinal strangulation
This loop of intestine was strangulatedwithin a hernia.
How would you know that this loop is viable or not?
Strangulated femoral hernia
Strangulated para-umbilical hernia
S ll i t ti l
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
48/165
GIT 348
Small intestinal gangrene
This gangrenous loop of small intestine was strangulated within a hernia.
What was the possible clinical presentation of this patient?
What is the next step in management?
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
49/165
GIT 349
Intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
50/165
GIT 350
Small bowlIntussusception
More pictures for intussusception will come later
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
51/165
GIT 351
Small bowel obstruction
Erect :
Multiple fluid levels
Supine :
Central distension of small intestinal loops
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
52/165
GIT 352
Volvulus
Si id
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
53/165
GIT 353
Sigmoidvolvulus
Sigmoid volvulus
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
54/165
GIT 354
Sigmoid volvulus
(late irreversible gangrene)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
55/165
GIT 355
Small bowl volvulus
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
56/165
GIT 356
Examples of dynamic obstruction
Intramural Malignant or
inflammatory stricture
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
57/165
GIT 357
Chronic intestinalobstruction due to CAdescending colon
Ba enema shows the shadow of the mass
Dilated intestinal loops are seen
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
58/165
GIT 358
Dilated bowelloops proximal tothe obstruction.
Arrow points tothe etiology of obstruction
Ba enema:
The ilio-cecal valve in this patient is incompetent
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
59/165
GIT 359
Examples of dynamic obstruction
Intraluminal Impacted faeces
Foreign body
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
60/165
GIT 360
Fecal impaction
As a result of chronic constipation,the patient is unable to expel stools, itfurther accumulates into a larger,harder mass that is impossible topass by normal defecation.
Impaction is most common ininactive elderly people
Symptoms include chronic
constipation. There can be fecalincontinence and paradoxical diarrheaas liquid stool passes around theobstruction
Foreign body
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
61/165
GIT 361
Foreign body
Phyto-bezoar in the jejunum
Peritonitis:
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
62/165
GIT 362
Peritonitis:
Primary Infection of the peritoneal fluid withoutintra-abdominal disease:Haematogenous spread Lymphatic spread Direct spread: usually associated with CAPD catheters Ascending infection: from the female genital tract
Secondary Inflammation of the peritoneum arisingfrom an intra-abdominal source:Infectious Non-infectious Blood Ischaemia Bile Chemical Foreign body
Perforation
Usually due to spreadinginflammation across thewall of an intra-
abdominal viscus
Localized
Generalized
Patho-physiology of Normally , the greater omentum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
63/165
GIT 363
protein-rich fibrinousexudate
Patho-physiology ofperitonitis
Early : hyperemia & fluid transudate
y , gchanges its position with
intestinal peristalsis & abdominal muscles contraction
Peritoneal inflammation willsuppress peristalsis & abdominal
muscles contractions
Clinically : Early: Guarding, reboundtenderness, decreased
or absent intestinalsounds
The greater omentum willadhere to & surround the
inflamed organ preventingfurther spread of inflammation
The exudate willsuppress peristalsis
(paralytic ileus), and limitsspread of infection
Ileus --- fluid accumulates withinthe intestine + intraperitoneal
exudate --- decreased intravascular volume --- hyopvolemia
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
64/165
GIT 364
The most common cause of generalized peritonitis is
perforation of an intra-abdominal viscus
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
65/165
GIT 365
Generalizedperitonitis
withfibrinousexudate
Infarction:
Area of ischemic necrosis caused by
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
66/165
GIT 366
Infarction:Aetiology ofinfarction
Occlusive Arterial :
Embolism Thrombosis Extrinsic compression Venous :
Thrombosis Extrinsic compression
Non-occlusive Shock:
Hypovolaemia Cardiogenic Sepsis
Vasoconstrictor drugs
impaired arterial supply or venous drainage
Arterial mesenteric vascular occlusion
Infarction of small intestine
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
67/165
GIT 367
Compare the dark red to grey infarcted bowel with the pale pink normal bowel atthe bottom. Some organs such as bowel with anastomosing blood supplies, or liver with a dual blood supply, are hard to infarct.
This bowel was caught in a hernia and the mesenteric blood supply wasconstricted by the small opening to the hernia sac.
What other causes can result in such massive intestinal infarction?
M i l
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
68/165
GIT 368
Mesenteric vascularocclusion
Irreversible small bowl ischemia
Mesenteric ischaemia
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
69/165
GIT 369
Mesenteric ischaemia
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
70/165
GIT 370
Intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
71/165
GIT 371
Intussusception (Ileo-ileal)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
72/165
GIT 372
Intussusception (Ileo-ileal)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
73/165
GIT 373
Intussusception (Ileo-ileal) - postmortum
Intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
74/165
GIT 374
Intussusception
Intussusception (Ileo-ileal)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
75/165
GIT 375
Intussusception (Ileo ileal)
What are the early clinical featuresof a child presenting withintussusception?
A child of about 6 months old, developssudden onset of screaming with drawingof the legs. The attacks are recurrent.Vommiting may occure early, stoolsmay be normal first, then the child
passes blood & mucous
Redcurrent jelly stools
Intussusception of ileum into the colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
76/165
GIT 376
The leading proximal, small bowelsegment (intussusceptum) telescopes into the distal, colonsegment (intussuscipens).
The small intestine (blue arrow) is goinginto the large intestine (green arrow)
Intussusception (Ileo-colic)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
77/165
GIT 377
p
Barium enema with rectal instillation under fluoroscopy is the gold standard for both diagnosing and red cing childhood ileo colic or colocolic intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
78/165
GIT 378
Barium enema showingintussusception
Passing from the rectum, the barium fillsthe colon untill a mass is noted (the intussusception)
Transverse colon
Barium enema is used for reduction of the intussusception
It is about to be completelyreduced (note the barium is going into the small intestine)
both diagnosing and reducing childhood ileo-colic or colocolic intussusception
Barium enema for diagnosis & reduction of intussusception
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
79/165
GIT 379
Head of intussusceptionis at hepatic flexure
Free flow of contrast intodistal small bowel indicates
complete reduction
Partial reduction
Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
80/165
GIT 380
Barium enema
Intussusception (Claw sign)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
81/165
GIT 381
The rectallyadministeredcontrast materialdraws around thehead of theintussusception(arrow) (Claw sign)
Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
82/165
GIT 382
Intussusception (Claw sign)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
83/165
GIT 383
Barium enema
Intussusception (Claw sign)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
84/165
GIT 384
Small IntestineOther pathological conditions
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
85/165
GIT 385
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
86/165
GIT 386
Meckels diverticulum
Inflamed
Remember the complicationsof Meckels diverticulum
Infection & obstruction (as theappendix)May contain gastric, colonic or pancreatictissue usually at the diverticulum mouth
Peptic ulceration with severe bleeding
Intussusception
Intestinal obstruction (band between umbalicus & diverticulum)
Meckels diverticulum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
87/165
GIT 387
ec e s d ve t cu u
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
88/165
GIT 388
Meckelsdiverticulum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
89/165
GIT 389
Crohns Disease
Regional enteritis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
90/165
GIT 390
Deep linear mucosal ulcerations, with edema of the mucosa between the ulcers
Remember that symptoms & signs of acute Crohns resemble acuteappendicitis
Chronic Crohns can cause enteric
strictures & fistulae
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
91/165
GIT 391
The Appendix
Normal appendix
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
92/165
GIT 392
Normal appendix (postmortem)
Acute appendicitis with gangrenous tip
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
93/165
GIT 393
Various positionsof appendix inorder offrequency:
1. Retrocecal 74%
2. Pelvic 21%
3. Paracecal 2%
4. Subcecal 1.5%
5. Preileal 1%
6. Postileal 0.5%
7. Sub-hepatic 8. Lt. iliac fossa in situs invertus
How can differentpositions alter theclassical clinicalpicture?
d
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
94/165
GIT 394
Acute Appendicitis
Acute Appendicitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
95/165
GIT 395
Acute Appendicitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
96/165
GIT 396
Note flakes of pus
Acute Appendicitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
97/165
GIT 397
Opened to showfecalith inside
Regarding appendicitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
98/165
GIT 398
g g ppa. The risk of developing the illness is greatest inchildhoodb. Mortality increases with age and is greatest in theelderlyc. 20% of appendices are extraperitoneal in a
retrocaecal positiond. Faecoliths are present in 75-80% of resectedspecimense. Appendicitis is a possible diagnosis in the
absence of abdominal tenderness All answers are correct.
Pelvic appendicitic can present with few abdominal symptoms & signs. Rectalexamination is t he key to diagnosis.
A i i i
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
99/165
GIT 399
Acute peritonitis
The loops of bowelare plasteredtogether withyellowish fibrinousexudate containing alarge number of neutrophils.
When this process heals, what complications may develop?
What are the factorsthat favor thedevelopment of diffuse peritonitis?
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
100/165
GIT 3100
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
101/165
GIT 3101
Subphrenic
abscess A pocket of infectionhas developedbeneath thediaphragm elevatingit as seen on thechest x-ray
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
102/165
GIT 3102
Colon
l d f h l
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
103/165
GIT 3103
Diverticular disease of the colon
Sigmoid Colon Most Common SiteDiverticula are small (0.5 to 1.0 cm in diameter) outpouchings of the colon that occur inrows at sites of vascular penetration between the single mesenteric taenia and one of
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
104/165
GIT 3104
rows at sites of vascular penetration between the single mesenteric taenia and one of the antimesenteric taeniae. At the sites of most diverticula, the muscular layer isabsent (see Figure 1). Technically, such lesions are really pseudodiverticula; truediverticula (which are much less common than pseudodiverticula) involve all layers of
the bowel wall. Nevertheless, both pseudodiverticula and true diverticula are generallyreferred to as diverticula
Diverticula are located at sites whereblood vessels enter the colonic wall
The sigmoid colon is the most common siteof diverticula: in 90% of patients withdiverticulosis, the sigmoid colon is involved.If a diverticulum becomes inflamed as aresult of obstruction by feces or hardenedmucus or of mucosal erosion, a localized
perforation (microperforation) may occur --a process known as diverticulitis. Theincidence of diverticulitis is about 10% to25% in patients with colonic diverticula
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
105/165
GIT 3105
Colonic diverticula are outpouchings of the mucosal layer of the large bowel through thesubmucosa and circular muscle layer of the bowel. Colonic diverticula are virtuallyrestricted to the sigmoid colon only; the rectum is spared as its complete longitudinalmuscle coat protects against their development. Diverticula stimulate marked hypertrophyof the circular muscle layer of the muscle coat. They tend to arise at weak points whereblood vessels penetrate the submucosa
Which of the following statements regarding colonic diverticula are true? (Tick all
those that apply)a)They are true diverticula which contain all the layers of the colonic wall.b)The sigmoid and rectum are the commonest site, as faeces are most solid here andrequire higher pressure to propelc)Their presence stimulates hypertrophy of the circular muscle layer of the large bowel.d)They tend to arise at weak point where blood vessels penetrate the submucosa of thelarge bowel.
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
106/165
GIT 3106
Profuse Bleeding in Complicated Diverticulitis Usually Ceases SpontaneouslyIn complicated diverticulitis, the disease process has progressed to obstruction,abscess or fistula formation, or free perforation. Complicated diverticulitis may beparticularly challenging to manage,[1] especially because patients may have no knownhistory of diverticular disease.[2] Gastrointestinal bleeding is a complication of diverticular disease in 30% to 50% of cases; in fact, diverticula are the most commoncolonic cause of lower GI bleeding. Approximately 50% of diverticular bleedingoriginates in the right colon, despite the low incidence of diverticula in this segment of the colon. Patients tend to be elderly[1] and to have cardiovascular disease andhypertension. Although patients may lose 1 to 2 units of blood, the bleeding usuallyceases spontaneously, and expeditious operative treatment generally is not necessary.
Barium enema- double contrast
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
107/165
GIT 3107
Diverticular disease of colon
Barium enema
Diverticular disease of colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
108/165
GIT 3108
Diverticular disease of colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
109/165
GIT 3109
Barium enema - Diverticular disease of colon
Ba. Enema-Diverticulitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
110/165
GIT 3110
Diverticulitis
An area of eccentricnarrowing ispresent in thesigmoid colon
(arrows). Withinthis areadiverticula areseen
Barium enema
Di ti l di f l l t t
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
111/165
GIT 3111
Diverticular disease of colon late stage
Theradiographtaken severaldays after theexamination,remains of contrastmaterial in thediverticula
demonstrateextendeddiverticulosisinvolving theentire colon
78 year old man is complainingof blood in the feces.
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
112/165
GIT 3112
This is the air-contrast barium
enema showing the sigmoid &descending colon
Does the X ray explain the clinical presentation? Explain.
What is the next step?
The film demonstrates several smallprojections extending out of thecolon. The appearance is typical of diverticulosis
SelectiveAngiography-
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
113/165
GIT 3113
g g p yActive bleedingfrom right-sidedcolonicdiverticulum
This early film
shows a focus of extravasation(arrow) arisingfrom a division of the right colicbranch of thesuperior mesenteric artery
The later filmd t t
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
114/165
GIT 3114
demonstratespersistent
extravasation inthis area withfilling of anadjacentdiverticular-likestructure
Adenomatous polyp (colon)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
115/165
GIT 3115
A polyp is any outgrowth of a mucosalsurface (as compared to a papilloma,
which is an outgrowth from squamous or transitional epithelium).
Polyps are particularly common in thecolon. This one is on a long stalk(pedunculated).
Polyps of the colon sometimes becomemalignant so that microscopicexamination is important.
The term adenoma is also used since
they are tumors of glandular origin.
How might a patient know that he had a polyp? (What is the possible clinicalpresentation?)
Inflamatory
Polyps of large intestine
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
116/165
GIT 3116
Inflamatory
Metaplastic
Hamartomatous
Neoplastic AdenomaTubular adenoma
Villous adenoma
Adenocarcinoma
Solitary adenomas are usually found during investigations of colonicbleeding
Villous adenomas usually cause diarrhea, mucous discharge & occasionallyhypokalemia
The risk of malignant transformation in an adenomatous polyp is related to
its size .
Adenomatous polypof the colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
117/165
GIT 3117
of the colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
118/165
GIT 3118
Colon polyp longitudinal section - wall layers are preserved (purly mucosal)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
119/165
GIT 3119
Familial adenomatous polyposis
Familial adenomatouspolyposis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
120/165
GIT 3120
Multiple adenomatous polyps of the cecum are seen here in a case of familialadenomatous polyposis , a genetic syndrome in which an abnormal genetic mutation leads todevelopment of multiple neoplasms in the colon.
p yp
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
121/165
GIT 3121
Multiple colonicadenomatous polyps infamilial adenomatous
polyposis
When those patients undergototal colectomy , they will need
regular follow-up. Why?
This is an autosomal dominant
familial disease. Why shouldmembers of affected families beregularly screened starting fromthe age of 10?
Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
122/165
GIT 3122
Familial polyposis of thecolon
Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
123/165
GIT 3123
Familial polyposis of thecolon
Familial adenomatous polyposis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
124/165
GIT 3124
Importance of screening program
Large bowl carcinoma occurs 10 20 years after the onset of polyposis
Operative options:
Colectomy with ilio-rectal anastomosis (needsregular follow-up for recurrent polps in the rectalstump. Treated by fulgration
Proctocolectomy with restorative ilio-analanastomosis
Proctocolectomy with iliostomy
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
125/165
GIT 3125
Cancer colon
cecum What are the possible
clinical presentations?
What are the differentmacroscopic types?
Common macroscopic varieties of colon carcinoma:
1. Annular
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
126/165
GIT 3126
2. Tubular
3. Ulcer 4. Cauliflower
Possible clinical presentations :
Recent alteration in bowl habbits with constipation needing more laxativesEmergency presentation with intestinal obstruction
Colonic bleeding or progressive anemia
Segmoid carcinoma may cause tenesmus
Palpable mass
Caecal carcinoma may be accidentally discovered during operation for appendicitis or appendicular abscess
Metastasis (usually liver) & ascitis
Cancer cecum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
127/165
GIT 3127
Terminal ileum
Remember thedifferent clinicalpresentations of
cancer cecum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
128/165
GIT 3128
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
129/165
GIT 3129 . Everted edge & necrotic floor Malignant ulcer of the colon
Resected segmentof colon from a 70
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
130/165
GIT 3130
of colon from a 70year old man with
iron deficiencyanemia
What condition
does this patient have? Why is he
anemic?
Colon Carcinoma
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
131/165
GIT 3131
Causing luminal stenosis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
132/165
GIT 3132 Cancer sigmoid colon
Barium enema
CA cecum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
133/165
GIT 3133
CA cecum
Barium enema
CA cecum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
134/165
GIT 3134
Barium enema
Apple-core type lesion in the sigmoidcolon typical of a carcinoma Air contrast barium film
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
135/165
GIT 3135
colon , typical of a carcinoma Air contrast barium film
Diverticulosis in the colon, in themiddle of which is found a small apple-core lesion typical of a carcinoma
Barium enema:
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
136/165
GIT 3136
Barium enema:
A 6 cm long section of the recto-sigmoid regionhas irregular contour,narrowed lumen (1 cm)and filling defect (arrow)
Ba. Enema-Carcinoma ofsigmoid colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
137/165
GIT 3137
sigmoid coloncausing complete
retrogradeobstruction
An irregular massencroaches on thelumen, which ultimatelynarrows to a thindistorted wisp of barium. The massinvolves both thesuperior and inferior margins of the sigmoidcolon, and is thereforecircumferential.
Diverticula are present distal to the obstructing mass. They represent anincidental finding
Barium enema
CA ascending colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
138/165
GIT 3138
g
Barium enema
CA ascending colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
139/165
GIT 3139
g
Barium enema
CA ascending colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
140/165
GIT 3140
g
Barium enema
CA hepatic fle re
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
141/165
GIT 3141
CA hepatic flexure
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
142/165
GIT 3142
Barium enema
CA i id l
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
143/165
GIT 3143
CA sigmoid colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
144/165
GIT 3144
Rectum &
Anal Canal
Thrombosed, infectedpiles
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
145/165
GIT 3145 What are the complications of piles?
What are the symptoms of piles?
1.Bright red painless bleeding. 2.Mucous discharge
3.Prolapsed piles 4.Pain only with prolapse
Complications of piles :
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
146/165
GIT 3146
1. Bleeding
2. Strangulation (prolapsed & gripped by theexternal sphincter impairing venous return)
3. Thrombosis of strangulated piles will follow if notreduced within an hour or two
4. Ulceration of the mucous membrane
5. Gangrene if strangulation occludes arterial supply
6. Suppuration if infection is superadded
7. Portal pyaemia
Cancer
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
147/165
GIT 3147
Rectum
rectumMalignant
ulcer
What are the organs that may be involved due to local spread of CA rectum?
Rectal cancer well within the reach of an examiner's finger
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
148/165
GIT 3148
Autopsy Picture
Anal canal
Malignantulcer in the
rectum
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
149/165
GIT 3149
The Colon
Normal Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
150/165
GIT 3150
The first two films are of an air contrast barium enema. There is bothbarium and air within the colon. By changing the position of the patient,
different areas are well outlined with the air. When the patient is lying on hisright side, the air accumulates on the left and vice-versa
The 3 rd film is a single contrast barium enema where only barium is instilledin the colon. The complete colon is well demonstrated. The colonic haustraare well seen. The terminal ileum and appendix are also filled
Hirschsprungs disease
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
151/165
GIT 3151
Hirschsprung s disease
Hirschsprungs disease
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
152/165
GIT 3152
Barium enema:The contrast materialoutlines a bowelsegment without
ganglions (arrows), above whichprestenotic dilatationis visible
Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
153/165
GIT 3153
Hirschsprungs disease
Barium enema
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
154/165
GIT 3154
Hirschsprungs disease
Ba enema Ulcerative cholitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
155/165
GIT 3155
The colon is short, withsmooth haustration andnarrow lumen.
Filling excesses (caused by ulceration) and fillingdefects (caused by mucosal regeneration) give a typicalpicture
Ba. Follow-through-Tuberculous enterocolitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
156/165
GIT 3156
The cecum and ascending
colon are markedly narrowed,nodular, and shortened. Theileocecal valve is gaping, andthe terminal ileum is narrowed
and nodular
Ba. Follow-through-Ischemic colitis
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
157/165
GIT 3157
segmental narrowing of the entire transversecolon. Within thenarrowed segment, thereare multiple nodular
indentations, many of which have theappearance of thumbprinting
Ba. Follow-through-Advanced Crohn'sdisease of the colon
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
158/165
GIT 3158
Diffuse narrowing of theascending colon andcecum, associated withextensive deep ulceration
seen in profile. Similar changes are present inthe upper descendingcolon. The terminal ileumis narrowed and has anodular mucosal pattern
Invertogram An invertogram may be used toinvestigate the extent of the defect inanal or rectal atresia
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
159/165
GIT 3159
anal or rectal atresia.The anus is marked with aradiopaque marker, and the babyinverted. A lateral radiograph is taken.The air in the rectum will rise to thehighest point, giving an indication of
the extent of the atresia
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
160/165
GIT 3160
Plain X-ray abdomen(erect position)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
161/165
GIT 3161
Duodenal atresia
Plain X-ray abdomen(erect position)
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
162/165
GIT 3162
Duodenal atresia
Ba. Meal follow-through- Smallbowel obstruction by an adhesiveband (Lt. lateral position).
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
163/165
GIT 3163
The film shows complete interruption of thelumen of the jejunum. Stretched circular mucosal folds without distortion or nodularity extend to the site of the lumeninterruption.
The patient gave a history of abdominal surgery done several years before. Palpationduring fluoroscopy shows fixation of the site of obstruction, usually to the anterior abdominal wall.
The absence of fold distortion or of nodularity is against a malignant cause for
the obstruction. When it is possible toobserve peristaltic activity changing theoutline of the obstructed segment (this bestseen in the single contrast phase), adiagnosis of non-malignant obstruction canbe confidently made even when there is a
history of abdominal surgery for malignancy.
Ba follow-through-Low gradeobstruction by a
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
164/165
GIT 3164
obstruction by asingle bandadhesion
Dilatation of the proximal jejunum terminating at a
sharply demarcated,short and narrowsegment (arrow); anormal fold pattern in anunderfilled lumen is seenbeyond the narrowedsegment. The patienthad abdominal surgeryseveral years before
Free air underdiaphragm
P f d
-
7/29/2019 GIT3 - Small, Large Surgical Pathology
165/165
Perforated
viscera