giovedì 23 marzo, ore 12 30 · the increasing emergence of drug-resistant bacterial strains calls...

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PASTEUR INSTITUTE SEMINAR SERIES Dott. Alessandro Giuffré Giovedì 23 marzo, ore 12:30 presso l'Aula Magna - Viale Regina Elena 295 Istituto di Biologia e Patologia Molecolari CNR The increasing emergence of drug-resistant bacterial strains calls for the development of new antibiotics. Bacterial energy metabolism offers opportunities for drug development, as shown by the ATPase inhibitor bedaquiline, the first approved antitubercular drug in over 40 years. The seminar will focus on cytochrome bd, a multifunctional respiratory oxidase which confers bacterial resistance to stress conditions and promotes virulence, being thus recognized as a potential drug target. per informazioni: [email protected] The bacterial respiratory oxidase cytochrome bd, a multifunctional target for next-generation antibiotics

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Page 1: Giovedì 23 marzo, ore 12 30 · The increasing emergence of drug-resistant bacterial strains calls for the development of new antibiotics. Bacterial energy metabolism offers opportunities

BIOL

GDEGLI EUCARIOTI

M

DI INTERESSE B

BIOLOGIA MOLECOLARE

M

GDEGLI EUCARIOTI

M

DI INTERESSE B

PASTEUR INSTITUTE SEMINAR SERIES

w

Dott. Alessandro Giuffré

Giovedì 23 marzo, ore 12:30presso l'Aula Magna - Viale Regina Elena 295

Istituto di Biologia e Patologia MolecolariCNR

The increasing emergence of drug-resistant bacterial strains calls for the development of new antibiotics. Bacterial energy metabolism offers opportunities

for drug development, as shown by the ATPase inhibitor bedaquiline, the first approved antitubercular drug in over 40 years. The seminar will focus on

cytochrome bd, a multifunctional respiratory oxidase which confers bacterial resistance to stress conditions and promotes virulence, being thus recognized as a

potential drug target.

per informazioni: [email protected]

The bacterial respiratory oxidase cytochrome bd,a multifunctional target

for next-generation antibiotics