genomic selection in dairy cattle
DESCRIPTION
Genomic Selection in Dairy Cattle. Dr.Wuttigrai Boonkum. Genomic Selection. Dairy cattle most are specialised dairy breed Holstein, Jersey, Brown Swiss, Ayrshire Some dual propose Simmental, Montbeliarde , Normande , etc More than 80% AI from AI companies - PowerPoint PPT PresentationTRANSCRIPT
Genomic Selection in Dairy Cattle
Dr.Wuttigrai Boonkum
Genomic Selection
• Dairy cattle most are specialised dairy breed Holstein, Jersey, Brown Swiss, Ayrshire• Some dual propose Simmental, Montbeliarde, Normande, etc• More than 80% AI from AI companies• Global exchange of genetic so international
genetic evaluation
Genomic Selection
P = G + EGenetic evaluation or Molecular genetics
Need time and data completeAppropriated major gene only
Genomic Selection,What does it bring us?
• Reliable breeding values at young age
– higher success rate to get top bulls
– lower costs for test proofs
– shorter generation-interval
Reliability of breeding values
Categorie Production Type Longevity
Parent average 35% 35% 30%
GS young bull 50-55% 45-50% 40-45%
1st EBV (prog.) 80% 75% 50-65%
2nd EBV (prog.) 89% 81% 50-80%
50% reliability is realistic
Advantages of Genomic Selection
• Increased genetic improvement (30-40%)
• Higher genetic level of test sires
• Higher genetic level of Delta embryo’s
• Wider portfolio of commercial bulls & higher level
• More outcross; less inbreeding
Disadvantages of Genomic Selection
• New method, not fully proven or tested
• Need to genotype a sufficiently large set of animals for accurate GEBV
• Across breed accuracy low• Genotypes still costly (10,000 bath/head)
1. การก�าหนดเป้าหมายของการป้ร�บป้ร�งพั�นธุ์��โคนม
1. การก�าหนดเป้าหมายของการป้ร�บป้ร�งพั�นธุ์��โคนม
ผลผล�ตน้ำ���น้ำม
องค์ ประกอบน้ำ���น้ำม
ล�กษณะโค์รงร��ง
ค์ว�มสมบ�รณ พั�น้ำธุ์�
ล�กษณะก�รต��น้ำท�น้ำโรค์
พั�นธุ์��โคนมของป้ระเทศไทย
TMZ TF
Friebrah
3. การใช้�ระบบผสมข�ามพั�นธุ์��ท!"เหมาะสม
Dairy cattle crossbreds
Traits TF TMZ FB
Milk yield (kg/head/lactation)Milk yield (kg/head/day)Day in milk (day)First oestrus after calving (day)Calving interval (day)Number of service per conception (times)Income (baht/lactation)Production cost (baht/lactation)Milk production cost (baht/kg)Net profit (baht)
4,517.76+384.1914.39+2.92314.45+24
69.17+28415.10+722.10+0.8752,406.0129,795.39
6.3722,610.62
3,902.57+460.9113.34+4.06292.30+28
68.19+43399.90+491.70+0.8245,269.8728,032.08
7.4917,237.79
2,472.90+456.129.20+1.21
268.50+5154.23+28
363.70+431.40+0.6928,676.2424,646.17
9.914,030.07
Table 3 Comparison of average of milk yield, reproductive performance and economic returns of Thai Friesian (TF), Thai milking zebu (TMZ) and Friebrah (FB)
Source: (สดใส และค์ณะ, 2549 ก,ข)
4. การใช้�พั�นธุ์�ศาสตร�โมเลก�ลในการป้ร�บป้ร�งพั�นธุ์��โคนม
Selection indexincluding
MA information
medium, low
Heritability
high
BLUPBLUP
TraditionalSelection indexby MT-BLUP
Pre-selectionby markerconfirmed
by MT-BLUPindex
MASSelection indexby MA-BLUP
GΔ GΔGΔ
GΔ
Figure 6 Dairy cattle improvement using BLUP and genetic marker scheme