genetics shireen rudina. first: a review of mendel’s laws 1.dominance 2.law of segregation- one...
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Genetics
Shireen Rudina
First: A review of Mendel’s Laws
1. Dominance
2. Law of Segregation- one allele from each parent
3. Law of Independent Assortment- each trait acts independently
Human Mendelian Traits
GENETIC TRAIT DOMINANT RECESSIVE
How about the rest?1. Multiple alleles: blood type
IA Type A blood
IB Type B blood
i Type O blood
IAIA Type A
Ia i Type A
IBIB Type B
IB i Type B
IAIB Type AB
ii Type O blood
Codominance
Question: A mother is Type A, and her child is type O
1. What is the child’s and mother’s phenotype?
2. There are two men claiming to be the father: one is Type B, and the other is Type AB. Which one is the father?
How about the rest?
2. Multiple genes for one trait
Sex Chromosomes: X and Y
Pedigree
• Method of following a trait down generations
Analyzing Pedigrees
Tay-Sachs Disease: Simple genetic trait
Tay-Sachs: A recessive disease
• Nervous system and brain rapidly deteriorate
• Children generally die by age 4
• Carriers are crucial
If daughter A marries someone with the trait, what is the probability that their child will be affected?
?
A
Replication
Materials
Replication process
Semiconservative Replication