genetic engineering. aka.. genetic modification make changes in dna code by insert or delete...
DESCRIPTION
1) Recombinant DNA Aka.. Gene Splicing made by combining DNA from > 1 source (often from very different species)TRANSCRIPT
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Genetic Engineering
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Genetic Engineering
aka .. Genetic Modification
Make changes in DNA code by Insert or delete specific genes
Use modern molecular biology techniques.
![Page 3: Genetic Engineering. aka.. Genetic Modification Make changes in DNA code by Insert or delete specific genes Use modern molecular biology techniques](https://reader035.vdocuments.us/reader035/viewer/2022062311/5a4d1b0f7f8b9ab05998e1aa/html5/thumbnails/3.jpg)
1) Recombinant DNA Aka .. Gene Splicing
made by combining DNA from > 1 source (often from very different species)
![Page 4: Genetic Engineering. aka.. Genetic Modification Make changes in DNA code by Insert or delete specific genes Use modern molecular biology techniques](https://reader035.vdocuments.us/reader035/viewer/2022062311/5a4d1b0f7f8b9ab05998e1aa/html5/thumbnails/4.jpg)
2) Gel electrophoresis An electric current smaller fragments -
fasterlarger ones – slower
DNA fragments move to
positive end
+
- A B DNA on murder weapon
![Page 5: Genetic Engineering. aka.. Genetic Modification Make changes in DNA code by Insert or delete specific genes Use modern molecular biology techniques](https://reader035.vdocuments.us/reader035/viewer/2022062311/5a4d1b0f7f8b9ab05998e1aa/html5/thumbnails/5.jpg)
3)Transgenic organisms
transgenic animal Mice--- so immune sys
more like humans- can study ‘em
Livestock --- leaner meat
carries a foreign gene, deliberately inserted into its genome.
transgenic plant Soybeans/corn/crops --- to
produce nat insecticiside so don’t have to be sprayed
Also: Improved Nutritional
Quality Insect Resistance Disease Resistance Drought Tolerance
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SMART
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4) Cloning
replacing the nucleus of an unfertilized ovum with the nucleus of a body cell from the organism.
first adult mammal cloned was Dolly in 1997
Clone --- genetically identical copy
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SMARTCome back!!!!
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5) DNA Fingerprinting Compare genetic similarities/differences b/w individuals. often used to ID source of blood / tissue found at crime
scenes. Polymerase Chain Reaction (PCR)
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6) Gene Therapy the insertion of normal or genetically altered genes into cells usually to replace defective genes (cancer & genetic disorders)
Eye cancer
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SMART
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My lab experience…….
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SMARTCome back!!!!