genetic disorders review. what is the disorder? chromosome 11 inability to manufacture melanin often...
TRANSCRIPT
![Page 1: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/1.jpg)
Genetic Disorders Review
![Page 2: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/2.jpg)
What is the disorder?
• Chromosome 11
• Inability to manufacture melanin
• Often shifting back and forth of eyes
• ANSWER: ALBINISM
![Page 3: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/3.jpg)
What is the disorder?
• Polygenic
• More common among Asians
• Opening in lip and roof of mouth
• ANSWER: cleft lip/cleft palate
![Page 4: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/4.jpg)
What is the disorder?
• Sex-linked trait
• Lack AHF factor
• “bleeder’s disease:
• ANSWER: hemophilia
![Page 5: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/5.jpg)
What is the disorder?
• Chromosome #4
• Too many copies of CAG – causes atrophy of the brain
• Does not manifest itself until 20’s-30’s
• ANSWER: Huntington’s
![Page 6: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/6.jpg)
What is the disorder?
• On X-chromosome
• Weakening of muscles
• Calf muscles enlarge first, usually in young boys
• ANSWER: Duchenne Muscular Dystrophy
![Page 7: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/7.jpg)
What is the disorder?
• Chromosome #15
• Accumulation of fat on the brain leads to degeneration of the nervous system
• Highest in Eastern European Jews
• ANSWER: Tay Sachs
![Page 8: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/8.jpg)
What is the disorder?
• Nondisjunction
• XXY
• Sterile, small testes, breast enlargement in males
• ANSWER: Klinefelters
![Page 9: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/9.jpg)
What is the disorder?
• Nondisjunction
• Trisomy 21
• Mental retardation, round face, extra fold on eyes, sluggish muscles
• ANSWER: Down Syndrome
![Page 10: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/10.jpg)
What is the disorder?
• Chromosome #12
• Breakdown of products of phenylalanine
• Mental retardation if diet does not omit phenylalanine
• ANSWER: PKU
![Page 11: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/11.jpg)
What is the disorder?
• Red blood cells collapse
• Carriers are somewhat resistant to malaria
• Found mostly in African-Americans and people of Mediterranean
• ANSWER: sickle-cell anemia
![Page 12: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/12.jpg)
What is the disorder?
• Nondisjunction
• Female XO, sterile
• Web between neck and shoulders
• ANSWER: Turner Syndrome
![Page 13: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/13.jpg)
What is the disorder?
• Sex-linked trait
• XcY would be affected male
• Inability to detect certain colors
• ANSWER: color blindness
![Page 14: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/14.jpg)
What is the disorder?
• Dominant chromosome #4
• Short stature, trident hand, prominent forehead
• Dwarfism Aa
• ANSWER: Achrondroplasia
![Page 15: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/15.jpg)
What is the disorder?
• Dementia
• Memory loss, confused
• Plaque on the brain
• ANSWER: Alzheimers
![Page 16: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/16.jpg)
What is the disorder?
• Long limbs, enlarged aorta
• Spidery fingers
• Abe Lincoln had it
• ANSWER: Marfans
![Page 17: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/17.jpg)
What is the disorder?
• Polygenic trait
• Shunt in brain to drain off fluid
• Opening of the vertebral column
• ANSWER: Spina bifida
![Page 18: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/18.jpg)
What is the disorder?
• Chromosome #7-salty skin in symptom
• Lack enzyme to break down mucous in respiratory and digestive tract
• Treatment with pounding chest
• ANSWER: Cystic Fibrosis
![Page 19: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/19.jpg)
What is this diagram called?
A.Pedigree
B.Punnett square
C.Kayrotype
![Page 20: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/20.jpg)
What is this diagram called?
A.Punnett square
B.Pedigree
C.Kayrotype
ANSWER: C
![Page 21: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/21.jpg)
What is this diagram called?A. Punnett
square
B. Pedigree
C. Karyotype
![Page 22: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/22.jpg)
What is this diagram called?A. Punnett
square
B. Pedigree
C. Karyotype
ANSWER: B
![Page 23: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/23.jpg)
What disorder is this?
A. TURNERS
B. KLINEFELTERS
C. DOWNS
D. METAFEMALE
![Page 24: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/24.jpg)
What disorder is this?
A. TURNERS
B. KLINEFELTERS
C. DOWNS
D. METAFEMALE
ANSWER: XXY
Klinefelters
![Page 25: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/25.jpg)
What disorder is this?
A. TURNERS B. KLINEFELTERS
C. METAFEMALE
D. DOWNS
![Page 26: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/26.jpg)
What disorder is this?
A. TURNERS B. KLINEFELTERS
C. METAFEMALE
D. DOWNS
ANSWER: D
![Page 27: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/27.jpg)
What are the chances of…
• two Achrondroplasia parents having a normal sized child?
• HINT: AA = dead
• Aa = achondroplasia
• aa = normal
• ANSWER: 25%
![Page 28: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/28.jpg)
What are the chances…
• Of a father with hemophilia and a wife of no hemophilia gene having a child with hemophilia? Could any children be carriers?
• ANSWER: 0% children; girls are carriers
![Page 29: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/29.jpg)
What disorder is this?
A. TURNERS B. KLINEFELTERS
C. METAFEMALE
D. DOWNS
ANSWER: A
![Page 30: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/30.jpg)
Which disorders ARE NOT caused by nondisjunction?
• Klinefelters• Turners• Cystic Fibrosis• Trisomy 21• Hemophilia
• ANSWERS:• Cystic Fibrosis• Hemophilia
![Page 31: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/31.jpg)
What is the genotypic ratio of the offspring of parents AO and BO?
A O
B
O
![Page 32: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/32.jpg)
What is the genotypic ratio of the offspring of parents AO and BO?
AB BO
AO OO
A O
B
O
What is the phenotypic ratio?
![Page 33: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/33.jpg)
What is the genotypic ratio of the offspring of parents AO and BO?
AB BO
AO OO
A O
B
O
What is the phenotypic ratio?
25% each blood types A, B, AB, O
![Page 34: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/34.jpg)
What type of blood can each of these blood types RECEIVE?
• A+• O+• O-• AB+• B-
• O+, A+• Only O+• Only O-• All +• O-, B-
![Page 35: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/35.jpg)
![Page 36: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/36.jpg)
In which phase of mitosis
• Are the chromosomes stopped to make a karyotype?
• A. prophase• B. telophase• C. metaphase• D. anaphase
• ANSWER: METAPHASE
![Page 37: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/37.jpg)
How are the chromosomes arranged
• In a karyotype?
• A. smallest to largest
• B. largest to smallest
• C. by color
• D. by shape
• ANSWER: B
![Page 38: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/38.jpg)
Who is the oldest child in generation III?
![Page 39: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/39.jpg)
Who is the oldest child in generation III?
• #1
![Page 40: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/40.jpg)
If red hair is recessive and is shaded in, how many boys and how many girls have red hair?
![Page 41: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/41.jpg)
If red hair is recessive and is shaded in, how many boys and how many girls have red hair?
• 2 boys + 2 girls
![Page 42: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/42.jpg)
Is this person a male or female?
![Page 43: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/43.jpg)
Is this person a male or female?
• MALE
![Page 44: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/44.jpg)
Is this person male or female?
![Page 45: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/45.jpg)
Is this person male or female?
• MALE
• Normal
Or what
Disorder?
![Page 46: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/46.jpg)
Is this person male or female?
• MALE
• Klinefelters
![Page 47: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/47.jpg)
Is this a male or female?
![Page 48: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/48.jpg)
Is this a male or female?
• Female- Normal or a disorder?
![Page 49: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/49.jpg)
Is this a male or female?
• Female- TURNERS SYNDROME
![Page 50: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/50.jpg)
This is a sex-linked trait. Why is there no trait (shaded) in
Generation II, but can be in III?
![Page 51: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/51.jpg)
Just carriers in Generation II.
![Page 52: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/52.jpg)
Which is NOT a sex-linked trait?
• Klinefelters• Color-Blindness• Hemophilia• Duchenne Muscular
Dystrophy
• ANSWER:Klinefelters
![Page 53: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/53.jpg)
Which is NOT genetic disorder?
• Color Blindness• AIDS• Marfans• Tay Sachs
• ANSWER:• AIDS
![Page 54: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/54.jpg)
Make a Punnett Square fortwo parents AS for sickle-cell
anemia.
![Page 55: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/55.jpg)
Make a Punnett Square fortwo parents AS for sickle-cell
anemia.A S
A
S
![Page 56: Genetic Disorders Review. What is the disorder? Chromosome 11 Inability to manufacture melanin Often shifting back and forth of eyes ANSWER: ALBINISM](https://reader030.vdocuments.us/reader030/viewer/2022032701/56649c9c5503460f9495bade/html5/thumbnails/56.jpg)
Make a Punnett Square fortwo parents AS for sickle-cell
anemia.
AA
(normal RBC)
AS
(resistant to malaria)
AS
(resistant to malaria)
SS
(sickle-cell disease)
A S
A
S