genes, environment and diet… do these really matter?

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GENES, ENVIRONMENT AND GENES, ENVIRONMENT AND DIET… DIET… Do these really matter? Do these really matter?

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Page 1: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, ENVIRONMENT AND GENES, ENVIRONMENT AND DIET…DIET…

Do these really matter?Do these really matter?

Page 2: GENES, ENVIRONMENT AND DIET… Do these really matter?

Living with autism….Living with autism….

Page 3: GENES, ENVIRONMENT AND DIET… Do these really matter?
Page 4: GENES, ENVIRONMENT AND DIET… Do these really matter?

October, 6October, 6thth 2009 - USA 2009 - USA

Page 5: GENES, ENVIRONMENT AND DIET… Do these really matter?

Oct. 6Oct. 6thth, 2009 Continued, 2009 Continued

Page 6: GENES, ENVIRONMENT AND DIET… Do these really matter?

EARLY EARLY DIAGNOSIS - 1DIAGNOSIS - 1

Alarmed by dramatic and baffling rise in Alarmed by dramatic and baffling rise in the prevalence of autism:the prevalence of autism:

Now affects as many as 1 in every 91 Now affects as many as 1 in every 91 (1:57 boys) children (3 – 17 yrs of age)!(1:57 boys) children (3 – 17 yrs of age)!

Though a brain disorder,Though a brain disorder, Current diagnosis is via behavioural Current diagnosis is via behavioural

observations,observations, Which are not reliable until child is 2 to 3 Which are not reliable until child is 2 to 3

yrs old.yrs old.

Page 7: GENES, ENVIRONMENT AND DIET… Do these really matter?

Early Diagnosis Early Diagnosis - 2- 2

““Finding a sensitive and accurate Finding a sensitive and accurate biological marker for autism that can biological marker for autism that can be revealed by a simple blood test be revealed by a simple blood test would have enormous implications would have enormous implications for diagnosing, treating and for diagnosing, treating and understanding more about the understanding more about the underlying causes of autism,” said underlying causes of autism,” said David G. AmaralDavid G. Amaral,, research director at research director at the UC Davis M.I.N.D. Institutethe UC Davis M.I.N.D. Institute..

Page 8: GENES, ENVIRONMENT AND DIET… Do these really matter?

Early Early Diagnosis - 3Diagnosis - 3

“ “Not being able to detect autism Not being able to detect autism

until a child is close to 3-years-until a child is close to 3-years-old eliminates a valuable old eliminates a valuable window of treatment opportunity window of treatment opportunity during the first few years of life during the first few years of life when the brain is undergoing when the brain is undergoing tremendous development.”tremendous development.”

Page 9: GENES, ENVIRONMENT AND DIET… Do these really matter?

EARLY DIAGNOSIS – EARLY DIAGNOSIS – THE GOAL ITHE GOAL I

Discovering an early diagnostic Discovering an early diagnostic test.test.

Imperative of research.Imperative of research. Growing view: Growing view: “Not all children with “Not all children with

autism are ‘doomed to autism’ at birth”.autism are ‘doomed to autism’ at birth”. Vulnerability.Vulnerability. Encounter after being born.Encounter after being born.

Genetic abnormality?Genetic abnormality? Environmental factor?Environmental factor? Dietary issue?Dietary issue?

Triggers the disorder.Triggers the disorder.

Page 10: GENES, ENVIRONMENT AND DIET… Do these really matter?

EARLY DIAGNOSIS – EARLY DIAGNOSIS –

THE GOAL IITHE GOAL II Studying the biological signs of autism.Studying the biological signs of autism. Could lead to new ways to prevent the Could lead to new ways to prevent the

disorder from ever occurring.disorder from ever occurring. And even if it can’t be prevented,And even if it can’t be prevented, Intervening early in life—ideally shortly Intervening early in life—ideally shortly

after birth—,after birth—, Could Could greatly improvegreatly improve the lifetime the lifetime

outlook for children with autism,outlook for children with autism, Particularly those who now respond Particularly those who now respond

poorly to therapy initiated when they poorly to therapy initiated when they are three or older.”are three or older.”

Page 11: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENESGENES, , ENVIRONMENT & ENVIRONMENT & DIET - 1DIET - 1 Genes: Genes: May, 2005 –May, 2005 –

chromosomal areas chromosomal areas implicated in Autismimplicated in Autism

5 – 20 genes involved5 – 20 genes involved Location on chromosome Location on chromosome

11 & 1711 & 17 Traits are both biological Traits are both biological

and behaviouraland behavioural Language delayLanguage delay Large head in family Large head in family

membersmembers Abnormal parental Abnormal parental

brain processing of brain processing of facesfaces

Degree to which Degree to which relatives can “read” relatives can “read” person’s mental stateperson’s mental state

Page 12: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENESGENES, , ENVIRONMENT & ENVIRONMENT & DIET - 2DIET - 2 Genes:Genes: Other – Other –

Left HandednessLeft Handedness Allergies & Immune System Allergies & Immune System

IssuesIssues History of early ear infectionsHistory of early ear infections Food IntolerancesFood Intolerances

Migraine sufferingMigraine suffering Testosterone-link?Testosterone-link?

Combination of Neuro-Combination of Neuro-toxicants & genes account toxicants & genes account for near 25% of for near 25% of Developmental problemsDevelopmental problems National Academy of Sciences - National Academy of Sciences -

20002000

Page 13: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENTENVIRONMENT & & DIET - 3DIET - 3 Environment:Environment:

Children diagnosed with Children diagnosed with autism - increased autism - increased astronomicallyastronomically

Leading scientists Leading scientists concluding - non-genetic concluding - non-genetic factors in the environment factors in the environment may be at least partially may be at least partially responsible for the rise of responsible for the rise of epidemic proportions epidemic proportions world-wideworld-wide

EVIDENCE OF HARMEVIDENCE OF HARM – – [email protected]@yahoogroups.com

Page 14: GENES, ENVIRONMENT AND DIET… Do these really matter?

Potentially hazardous Potentially hazardous chemicals should be judged chemicals should be judged

“guilty until proven innocent. …“guilty until proven innocent. …But the EPA doesn’t work that But the EPA doesn’t work that

way…”way…”EPA Advisor, Prof. John Wargo, Yale UniversityEPA Advisor, Prof. John Wargo, Yale University

Page 15: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENTENVIRONMENT & & DIET - 4DIET - 4 Environment:Environment:

PCB’s and Language PCB’s and Language Development Development

Environmental factors may Environmental factors may combine with genetic combine with genetic predispositions – 51 over-predispositions – 51 over-lapping geneslapping genes

““Kids at Risk”Kids at Risk” - US News and - US News and World Report, June 19th, 2000 – World Report, June 19th, 2000 – linking chemicals in the linking chemicals in the environment to the rising environment to the rising numbers of children with numbers of children with learning problemslearning problems

1/6 of children in USA suffer 1/6 of children in USA suffer from Autism, ADD/H, Dyslexia or from Autism, ADD/H, Dyslexia or other Learning Disabilitiesother Learning Disabilities

Page 16: GENES, ENVIRONMENT AND DIET… Do these really matter?

The Normally Developing BrainThe Normally Developing Brain

From uterus throughout adolescenceFrom uterus throughout adolescence

series of complex processes in a series of complex processes in a carefully timed sequencecarefully timed sequence

Cells proliferate, move to correct spot, Cells proliferate, move to correct spot, synapses form, neural circuits are synapses form, neural circuits are refined, neurotransmitters and refined, neurotransmitters and receptors growreceptors grow

Neuro-toxicants may slow, accelerate, Neuro-toxicants may slow, accelerate, or otherwise modify any of these or otherwise modify any of these processes!processes!

Page 17: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENENVIRONMENTT & & DIET - 5DIET - 5 ENVIRONMENTAL ENVIRONMENTAL ISSUE? ISSUE?

AutismAutism in California: 1987 – in California: 1987 – 1998: 210 % increase from 3,164 1998: 210 % increase from 3,164 – 11,995!– 11,995!

Learning ProblemsLearning Problems – New York: – New York: jumped 55% from 132,000 to jumped 55% from 132,000 to 204,000 - 1983 and 1996.204,000 - 1983 and 1996.

The Lead Factor: The Lead Factor: significantly significantly higher bone-lead levels in juvenile higher bone-lead levels in juvenile court convicts – May 2000.court convicts – May 2000.

Breath-taking Pesticides:Breath-taking Pesticides: New New York: pregnant women breath in York: pregnant women breath in at least 3 neuro-toxic pesticides at least 3 neuro-toxic pesticides able to cause disorders in able to cause disorders in foetuses – March, 2000.foetuses – March, 2000.

Page 18: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENTENVIRONMENT & DIET & DIET – 6– 6

““heavy metals”heavy metals”Aluminium Aluminium ToxicityToxicity

Speech disturbanceSpeech disturbance

HesitancyHesitancy

StutteringStuttering

DisarthriaDisarthria

DyspraxiaDyspraxia

DysphasiaDysphasia

Myoclonic movementsMyoclonic movements

Possible dementiaPossible dementia

Directional disorientaitonDirectional disorientaiton

Epileptic seizuresEpileptic seizures

Senile DementiaSenile Dementia

AlzheimersAlzheimers

Constipation, colic & nauseaConstipation, colic & nausea

Gastric irritationGastric irritation

Loss of appetiteLoss of appetite

Local numbnessLocal numbness

Loss of energyLoss of energy

Excessive perspirationExcessive perspiration

Aluminium cooking Aluminium cooking utencilsutencils

SaltsSalts

Food additivesFood additives

AntacidsAntacids

Anti-diarrhoea medsAnti-diarrhoea meds

CosmeticsCosmetics

Baking powderBaking powder

Pharmaceutical and Pharmaceutical and personal hygiene personal hygiene preparationspreparations

Soya baby formulasSoya baby formulas

Aluminium rich Aluminium rich drinking waterdrinking water

Dental fillingsDental fillings

Page 19: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENTENVIRONMENT & &

DIET – 7DIET – 7

““heavy metals”heavy metals”CadmiumCadmium Toxic to every human systemToxic to every human system

Biological half-life = 20 – 30 Biological half-life = 20 – 30 years!years!Renal disease Prostatic carcinomaRenal disease Prostatic carcinomaHypertension AnaemiaHypertension AnaemiaSevere pulmonary NauseaSevere pulmonary Nausea

and bronchial irritation Sodium retentionand bronchial irritation Sodium retentionNausea VomitingNausea VomitingEmphysema Gastric tract Emphysema Gastric tract irritationirritationImpaired acid secretion Joint pains Impaired acid secretion Joint pains Proteinuria GlycosuriaProteinuria GlycosuriaAminoaciduria Reduced body Aminoaciduria Reduced body temptempElevated erythrocyte clearanceElevated erythrocyte clearanceLoss of taste and touch due to zinc Loss of taste and touch due to zinc

deficiencydeficiencyLoss of appetite – zinc deficiencyLoss of appetite – zinc deficiencyLoss of teeth and damage to oral cavityLoss of teeth and damage to oral cavityImpaired adrenal functionImpaired adrenal functionHyperactivity in childrenHyperactivity in children

SMOKING!SMOKING!

Saltwater fishSaltwater fish

ShellfishShellfish

Black teaBlack tea

Pigments Pigments

PaintsPaints

BatteriesBatteries

Galvanised Galvanised pipespipes

SolderSolder

Car exhaustsCar exhausts

Industrial Industrial fumes (oil / fumes (oil / coal industry)coal industry)

Polluted Polluted waterwater

Page 20: GENES, ENVIRONMENT AND DIET… Do these really matter?

CARIN S. SMIT – C/CLINICAL METAL CARIN S. SMIT – C/CLINICAL METAL TOXICOLOGIST - SYNAPSE AFRICA NEURO-TOXICOLOGIST - SYNAPSE AFRICA NEURO-

NUTRITIONAL CLINICNUTRITIONAL CLINIC

UraniumUranium Toxic to every human systemToxic to every human system

Biological half-life = 4.5 billion Biological half-life = 4.5 billion years!years!Renal disease Prostatic carcinomaRenal disease Prostatic carcinomaHypertension AnaemiaHypertension AnaemiaSevere pulmonary NauseaSevere pulmonary Nausea

and bronchial irritation Sodium retentionand bronchial irritation Sodium retentionNausea VomitingNausea VomitingEmphysema Gastric tract Emphysema Gastric tract irritationirritationImpaired acid secretion Joint pains Impaired acid secretion Joint pains Proteinuria GlycosuriaProteinuria GlycosuriaAminoaciduria Reduced body Aminoaciduria Reduced body temptempElevated erythrocyte clearanceElevated erythrocyte clearanceLoss of taste and touch due to zinc Loss of taste and touch due to zinc

deficiency Cancerdeficiency CancerLoss of appetite – zinc deficiencyLoss of appetite – zinc deficiencyLoss of teeth and damage to oral cavityLoss of teeth and damage to oral cavityImpaired adrenal function DeformityImpaired adrenal function DeformityHyperactivity in children Brain injuryHyperactivity in children Brain injury

Thermal Thermal Coal-fired Coal-fired power power plantsplants

Nuclear Nuclear reactorsreactors

Depleted Depleted Uranium in Uranium in Ammunition Ammunition and and warheadswarheads

GENES, GENES, ENVIRONMENTENVIRONMENT & DIET & DIET

– 8– 8

““heavy metals”heavy metals”

Page 21: GENES, ENVIRONMENT AND DIET… Do these really matter?

CARIN S. SMIT – C/CLINICAL METAL CARIN S. SMIT – C/CLINICAL METAL TOXICOLOGIST - SYNAPSE AFRICA NEURO-TOXICOLOGIST - SYNAPSE AFRICA NEURO-

NUTRITIONAL CLINICNUTRITIONAL CLINIC

Courtesy: Gethin Chamberlain – UK Guardian

Page 22: GENES, ENVIRONMENT AND DIET… Do these really matter?
Page 23: GENES, ENVIRONMENT AND DIET… Do these really matter?
Page 24: GENES, ENVIRONMENT AND DIET… Do these really matter?
Page 25: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENTENVIRONMENT & &

DIET – 8DIET – 8

““heavy metals”heavy metals”MercuryMercury HIGHLY TOXIC TO HUMANS HIGHLY TOXIC TO HUMANS – Inhibits enzyme activity– Inhibits enzyme activity!!

Worldwide production – Worldwide production – exceeds 10,000 tons p/aexceeds 10,000 tons p/aCNS disorders and paralysis CNS disorders and paralysis

Destroys red blood cells Destroys red blood cells Birth defectsBirth defects

Causes chromosomal damage Metallic taste Causes chromosomal damage Metallic taste

Loss of appetite and weight Loss of appetite and weight

Inflamed gums and loose teeth and Inflamed gums and loose teeth and

Skin irritationsSkin irritations

Increased salivation IrritabilityIncreased salivation Irritability

Hyperactivity Blushing Hyperactivity Blushing

Increased blood pressure PsychosesIncreased blood pressure Psychoses

Depression Loss of energy AllergiesDepression Loss of energy Allergies

Hallucinations Ataxia Hallucinations Ataxia Asthma Asthma Convulsions Convulsions

Extreme tremorExtreme tremor

Acute mental and emotional Kidney failureAcute mental and emotional Kidney failure

DisordersDisorders

Frequent Frequent consumption of consumption of large fish – e.g. large fish – e.g. tunatuna

PlasticPlastic

Printer’s inkPrinter’s ink

PigmentsPigments

CosmeticsCosmetics

PesticidesPesticides

Dental Dental amalgamsamalgams

Fabric Fabric softenerssofteners

Chlorine bleachChlorine bleach

Grains treated Grains treated with fungicideswith fungicides

VaccinationsVaccinations

Page 26: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENTENVIRONMENT & &

DIET – 9DIET – 9

““heavy metals”heavy metals”LeadLead HIGHLY TOXIC – Inactivates HIGHLY TOXIC – Inactivates enzymesenzymes!!

Renal, CNS Renal, CNS (AFFECTS EMOTIONAL (AFFECTS EMOTIONAL AND PHYSICAL HEALTH – REDUCES AND PHYSICAL HEALTH – REDUCES

INTELLECTUAL CAPACITY)INTELLECTUAL CAPACITY), , endocrine, immune and endocrine, immune and hemopoietic damagehemopoietic damage: : Fatigue Fatigue (anaemia), Constipation, Abdominal pain, (anaemia), Constipation, Abdominal pain, Anorexia, Altered sleep patterns, Irritability, Anorexia, Altered sleep patterns, Irritability, DiarrhoeaDiarrhoea

Nausea, Headaches,Nausea, Headaches,

Vertigo, Tremor, Vertigo, Tremor,

Joint pain, Psychoneuroses, Colic, Loss of Joint pain, Psychoneuroses, Colic, Loss of muscle strength, muscle strength,

Paresthesia, Paresthesia,

Neuropathy and encephalopathy, Aggression Neuropathy and encephalopathy, Aggression during adolescence,during adolescence,

Mental retardation, learning disabilities, Mental retardation, learning disabilities, speech disturbance, speech disturbance,

Intermittent fever, DehydrationIntermittent fever, Dehydration

ADVANCED STAGE: LETHAL!ADVANCED STAGE: LETHAL!

Leaded petrol Leaded petrol (gasoline) – (gasoline) – 600,000 tons p/a 600,000 tons p/a into atmosphere!into atmosphere!

Lead paint – bitter Lead paint – bitter legacy of legacy of governmental governmental failure to act!failure to act!

Burning coalBurning coal

Smelting worksSmelting works

Batteries Batteries PigmentsPigments

PotteryPottery

CrystalCrystal

Page 27: GENES, ENVIRONMENT AND DIET… Do these really matter?
Page 28: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENT & ENVIRONMENT & DIETDIET - 1- 1 WHY DIET?WHY DIET?

Genetic Genetic predisposition to predisposition to weak digestionweak digestion

Enzyme Enzyme suppressing suppressing environmental environmental insultsinsults

Foods which Foods which suppress suppress enzymatic functionenzymatic function

Page 29: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENT & ENVIRONMENT & DIETDIET - 2- 2 Family history of Family history of

digestive problemsdigestive problems Heavy metals Heavy metals

suppress enzyme suppress enzyme functionfunction

Certain foods Certain foods contain chemicals contain chemicals which suppress which suppress pancreatic pancreatic enzymesenzymes

Page 30: GENES, ENVIRONMENT AND DIET… Do these really matter?

GrainsGrains DairyDairy

Legumes, Legumes, Nuts, Seeds Nuts, Seeds

& Pulses& PulsesGluten(60)/Gluten(60)/

Gliadin(40)Gliadin(40)CaseinCasein Gliadin(100)Gliadin(100)

Gluta-Gluta-morphinemorphine / / Gliadino-Gliadino-

morphinemorphine

Caso-Caso-morphinemorphine

Gliadino-Gliadino-morphinemorphine

Amino AcidsAmino Acids Amino AcidsAmino Acids Amino AcidsAmino Acids

HOW PROTEINS BREAK DOWN…

Page 31: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENT & ENVIRONMENT & DIET DIET - 3- 3

GF/CF GF/CF versusversus HistoricallyHistorically – milk – milk

& wheat& wheat ThenThen all gluten- all gluten-

containing containing products and products and dairydairy

ThenThen lists of lists of gluten and gluten and casein-containing casein-containing foodsfoods

GF/C/F/GF/C/F/G/FG/F THE PROBLEM:THE PROBLEM:

All grains contain All grains contain gluten & most gluten & most contain gliadin toocontain gliadin too

Gliadin is the Gliadin is the toxic toxic protein that protein that causes coeliacs causes coeliacs to lose endothelial to lose endothelial cells!cells!

100% of protein in 100% of protein in legumes, nuts, legumes, nuts, seeds and pulses seeds and pulses is is GLIADINGLIADIN!!

Page 32: GENES, ENVIRONMENT AND DIET… Do these really matter?

“There are three kinds of lies: lies, damn lies and statistics…”Benjamin Disraeli, 1804 - 1881

Page 33: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENT & ENVIRONMENT & DIETDIET - 5 - 5

““Lies, damn lies Lies, damn lies and statistics…” and statistics…” – – Pinnochio Pinnochio syndrome!syndrome!

Soya, Nuts, Soya, Nuts, Seeds, Milk, Seeds, Milk, Grains – are Grains – are they good for they good for you?you?

What is there What is there to loseto lose?!?!

Page 34: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENT & ENVIRONMENT & DIETDIET - 4- 4 LEGUMESLEGUMES – –

Soya i.s.o. Milk!Soya i.s.o. Milk! Nuts, Seeds Nuts, Seeds

and pulsesand pulses - - as alternative as alternative protein protein sources???sources???

““NO! No! NO! No! No!”No!”

Page 35: GENES, ENVIRONMENT AND DIET… Do these really matter?

GENES, GENES, ENVIRONMENT &ENVIRONMENT & DIETDIET - 5- 5 Nutrients LostNutrients Lost

CalciumCalcium

MagnesiumMagnesium

ZincZinc

B-ComplexB-Complex

Essential aminoEssential amino

acidsacids

Essential fatty acidsEssential fatty acids

Trace elementsTrace elements

Vitamin CVitamin C

Page 36: GENES, ENVIRONMENT AND DIET… Do these really matter?

WHY DIET?WHY DIET?

Clears brain of opiates (morphines)Clears brain of opiates (morphines) Improves appetite for other foods – wider Improves appetite for other foods – wider

food choicesfood choices StopsStops neural pruning whilst heavy metals neural pruning whilst heavy metals

issues are being addressedissues are being addressed StopsStops insults to immune system (WBC’s & insults to immune system (WBC’s &

DPPIV)DPPIV) StopsStops mineral-leeching (Ca, Mg, Zn…) mineral-leeching (Ca, Mg, Zn…) Makes body feel better – health benefitsMakes body feel better – health benefits Heals gastro-intestinal systemHeals gastro-intestinal system Improves mood, focus and memoryImproves mood, focus and memory StopsStops mal-digestion, malabsorption and mal-digestion, malabsorption and

malnutritionmalnutrition

Page 37: GENES, ENVIRONMENT AND DIET… Do these really matter?

METALLOTHIONEIN – METALLOTHIONEIN – WHAT IT IS AND WHAT IT WHAT IT IS AND WHAT IT

DOES?DOES? Body’s control mechanism for

copper and zinc Development of neurons Detoxifies heavy metals Matures the GI tract Anti-oxidation Boosting immune function Delivers zinc to cells

Page 38: GENES, ENVIRONMENT AND DIET… Do these really matter?

METALLOTHIONEIN-METALLOTHIONEIN-RELATED ISSUES IN RELATED ISSUES IN

AUTISMAUTISM Incomplete breakdown of Incomplete breakdown of

casein/gluten/gliadin protein by zinc casein/gluten/gliadin protein by zinc dependent enzymesdependent enzymes

Disrupted ability to combat yeastDisrupted ability to combat yeast Reduced production of stomach acidReduced production of stomach acid Impaired stimulation of pancreas by Impaired stimulation of pancreas by

secretinsecretin Leaky gut syndromeLeaky gut syndrome Inability to clear body of Inability to clear body of heavy metalsheavy metals Disordered immune systemDisordered immune system Neurological changes we ultimately see in Neurological changes we ultimately see in

AutismAutism

Page 39: GENES, ENVIRONMENT AND DIET… Do these really matter?

11 HELPFUL BIO-MECIDAL SCREENING – HELPFUL BIO-MECIDAL SCREENING – Checking metabolism

Mineral Hair Analysis – Micro Trace Minerals Lab - Germany Urinary Chelation Tests – Micro Trace Minerals Lab - Germany Advanced Metallothionein Profile – Great Plains - USA Organic Acid Testing – Great Plains USA Urinary Peptide Analysis – University of Oslo – Norway (Other: Porphyrin Testing / Comprehensive Allergy Test, etc)

22 INITITAL CONSULTATION – INITITAL CONSULTATION – Recommendations given to commence appropriate sensory-motor integration therapies and employ methods to advance general detoxification: Auditory Integration Training Magnesium-Sulphate baths Jogging, bouncing which enhance cardio-vascular

function Neuro-Cognitive Mobilisation – brain-stem activation Have water tested for toxicity – switch to “good” water

i.s.o. other drinks

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33 FOLLOW-UP CONSULTATION REGARDING FOLLOW-UP CONSULTATION REGARDING FINDINGS: FINDINGS: Plan a follow-up consultation within 8 weeks of initial bio-medical screening tests (personal or tele-conferencing) Discuss yeast & fungal eradication, Diet & Super-nutrition; Methylcobalamin-

injections, MT Promoter (?), chelation. Management plan for further therapeutic interventions.

44 COMMENCE YEAST / FUNGAL ERADICTION & COMMENCE YEAST / FUNGAL ERADICTION & ENSURE OPTIMAL MINERAL AND TRACE ELEMENT ENSURE OPTIMAL MINERAL AND TRACE ELEMENT STATUS STATUS

55 COMMENCE CHELATION – COMMENCE CHELATION – Oral or Intravenous – liver Oral or Intravenous – liver and kidney function tests.and kidney function tests.

66 IMPERATIVE: IMPERATIVE: Follow-up tests EVERY 3 – 6 MONTHSFollow-up tests EVERY 3 – 6 MONTHS Mineral Hair Analysis, Urinary chelation, AMP, Organic Mineral Hair Analysis, Urinary chelation, AMP, Organic

Acids, Iron StoresAcids, Iron Stores

Page 41: GENES, ENVIRONMENT AND DIET… Do these really matter?