Introduction Chief Executive Officer: Professor Gary Ford, CBE Chief Operating Officer: Dr Paul Durrands

AHSN core purpose – health and wealth

• Licensed by NHS England for 5 years to deliver four

objectives:

• Focus on the needs of patients and local populations:

support and work in partnership with commissioners and

public health bodies to identify and address unmet health and

social care needs, whilst promoting health equality and best

practice.

• Speed up adoption of innovation into practice to improve

clinical outcomes and patient experience - support the

identification and more rapid uptake and spread of research

evidence and innovation at pace and scale to improve patient

care and local population health.

• Build a culture of partnership and collaboration: promote

inclusivity, partnership and collaboration to consider and

address local, regional and national priorities.

• Create wealth through co-development, testing, evaluation

and early adoption and spread of new products and services.

The Oxford AHSN

• Our Vision. Best health for our population and prosperity for our region

• Our Mission. We will support collaboration, research and innovation across the NHS, universities and business, building on our strengths to deliver exemplary care and create the strongest life science cluster

The Oxford AHSN • Strategy and objectives. Our strategy is to be facilitative and

work through our partners

• We will build infrastructure and support the development of people to accelerate innovation and early adoption in our NHS partners that improves health and adds value

• This will include funding clinical networks and developing teams for commercial development and innovation adoption to promote and accelerate change

• Our values. We will be inclusive, transparent and fair

What and where

Oxford AHSN – 1 of 15 in England

3.3M population

Annual NHS spend circa £5bn

NHS employees 65,000

12 Clinical Commissioning Groups

4 Local Enterprise Partnerships

12 Councils

Major international companies

569 healthcare and life science

organisations

Complex and varied landscape

http://www.oxfordahsn.org/our-work/wealth-creation/obn-map/

Oxford AHSN Life Sciences map link:

Our healthcare, academic and LEP partners 11. South Central Ambulance Service FT 11

New partnerships

Universities

Life Science

Industry

Wealth Creation

Clinical Innovation

Adoption

Research &

Development

Interaction between NHS and universities was not

strong – AHSNs are addressing this

Patients

and Public

Best Care

INVENTION EVALUATION ADOPTION DIFFUSION

NIHR

Infrastructure

BRCs, BRUs, CRFs

NIHR

Infrastructure

CLAHRCs

AHSCs AHSNs

NHS

Patient Care

NHS

Patient Care

NIHR

Infrastructure

Clinical Research Network

NIHR

Programmes

MRC

Programmes

AHSNs, AHSCs and the

Research and Innovation Landscape

Oxford AHSN Governance Structure

Programme Office

Oxford AHSN Board – Nigel Keen (Chair), Gary Ford (CEO) and Paul Durrands (COO) and oversight group chairs

Joe

Harrison

OSG

Best Care

Programme

Clinical

Networks

Jonathan

Michael

OSG

R & D

Programme

Projects

Nick

Edwards

OSG

Wealth

Creation

Programme

Projects

Stuart

Bell CBE

OSG

Informatics

Theme

Projects

Justin

Wilson

OSG

PPIEE

Theme

Projects

AHSN Partnership

Council (annual general meeting open to all)

AHSN Partnership

Board (all NHS CEOs, HEI Leads, LEPs, CCGs,

HETV, SCN, ABPI, ABHI

3 meetings per year)

Anne

Eden

OSG

Clinical

Innovation

Adoption

Projects

We welcome new partners

Great Western Hospitals (NHS) FT is working with our clinical networks, R&D network and

Clinical Innovation Adoption programmes. Bedford Hospitals is working with Imaging Network

and has EBH Fellowship. Frimley Park is engaged in Clinical Innovation Adoption programme.

Oxford AHSN Core Team Structure

CEO Gary Ford

Chair Nigel Keen

COO Paul Durrands

Executive Assistant

Pam Munnelly

Programme Officer

Amy Shearman

PPIEE Sian Rees

Informatics Mike Denis

Wealth Creation

Nick Scott-Ram MBE

R&D (Gary Ford)

Programme and Theme Senior Responsible Officers Best Care

Chandi Ratnatunga

Interim

Programme Director

Simon Hay

Senior Project Manager –

Clinical Networks Will Pank

Commercial Development

Manager Buckinghamshire

/Bedfordshire Nicki Bromwich

Commercial Development

Manager Berkshire

Hugh Penfold

Project Manager

TBC

Director of Corporate

Affairs Megan

Turmezei

Head of Communications

Martin Leaver

Finance Manager

Paul Foster

(through OUH)

Innovation Adoption Manager Sue Ikin

Innovation Adoption Manager

Dominic Balchin

Informatics Lead

Simon Pizzey

Communications and Informatics Administrator

Rochelle Nelson

Implementation Manager

Sarah Pyne

Innovation and Wealth

Administrator Lauren Davis

Procurement Contracts

IT

(Provided by OUHT)

Clinical Innovation Adoption

Tracey Marriott

Clinical Engagement

Lead Katie James

The Oxford AHSN – 4 programmes • Best Care programme

• 10 AHSN funded clinical networks and working with Thames Valley Strategic Clinical Networks

• Continuous learning – working with Health Education Thames Valley

• Evidence Based Healthcare Fellowships

• Patient Safety Academy (and Patient Safety Collaborative)

• Clinical Innovation Adoption programme – adoption at scale of innovations to improve patient outcomes, experience and safety. Clinically led, working with NHS providers and industry

• Research and Development programme - work with Thames Valley and South Midlands Local CRN, NIHR, CLAHRC, life science industry and other research infrastructure

• Wealth Creation programme - to help the region become the favoured location for inward life science investment, life science business creation and growth

Best Care The Oxford AHSN is funding and supporting ten clinical networks for driving improvements in health. We also work closely with the Thames Valley Strategic Clinical Networks (SCN).

1. Children - Prof Andrew Pollard 2. Dementia - Dr Rupert McShane 3. Depression and anxiety - Prof David Clark 4. Diabetes - Prof Stephen Gough/Dr Katharine Owen 5. Early intervention in mental health - Dr Belinda Lennox 6. Imaging - Prof Fergus Gleeson 7. Maternity - Mr Lawrence Impey 8. Medicines optimisation - Mr Boo Vadher 9. Mental and physical comorbidity - Prof Michael Sharpe 10. Out of Hospital Care - Dr Daniel Lasserson 11. Cancer SCN – Dr Bernadette Lavery 12. Cardiovascular SCN – Dr Will Orr

Mr Chandi Ratnatunga, Associate Medical Director at Oxford University Hospitals NHS Trust, is the Senior Responsible Office for the Best Care Programme. He has been involved in the Oxford AHSN since June 2012, working on the development of clinical networks, a unique feature of the Oxford AHSN.

Clinical Network /

Programme / Theme

Host Lead PIDs (Projects)

Anxiety & Depression

Clinical Network

Oxford Health NHS FT Prof David Clark • Reduction in unwarranted variation

• IAPT service development

• Pathfinder IAPT projects

Children’s Clinical

Network

Oxford University Hospitals

NHS Trust

Prof Andrew Pollard • e-Clinics

• Improve immunisation coverage

• Reduce variation in care (Practice

Educator)

• Research facilitation

Co-morbidity Clinical

Network

Oxford University Hospitals

NHS Trust

Prof Mike Sharpe • Reduce variation in care

Dementia Clinical

Network

Oxford Health NHS FT Dr Rupert McShane • ΔG™ Nutraceutical

• Reduce variation in care

• Neighbourhood return

• Data capture systems

Diabetes Clinical

Network

Oxford University Hospitals

NHS Trust

Dr Katharine Owen • Islet cell transplantation

• Tackling variation in diabetes care

• Gestational diabetes telehealth

• Young adult diabetes

Early Intervention

Clinical Network

Oxford Health NHS FT Dr Belinda Lennox / Dr

Mark Allsopp

• Reduce variation in care

• Research recruitment

• Enhancing care continuity and

extending the model of early

intervention

• Common assessment

Imaging Clinical Network Oxford University Hospitals

NHS Trust

Prof Fergus Gleeson • Creation of Radiology on-call /

specialist opinion network

• Imaging trial development and

delivery

• Early PET-CT in Lung Cancer

• Audit of multi-provider imaging

services

Clinical Network /

Programme / Theme

Host Lead PIDs (Projects)

Maternity Clinical

Network

Oxford University Hospitals

NHS Trust

Mr Lawrence Impey • Improving Fetal Medicine care and

consistency

• Maternity information sharing

Medicines Optimisation

Clinical Network

Oxford University Hospitals

NHS Trust

Mr Bhulesh Vadher • Reduction in unwarranted variation

• QIPP and waste reduction projects

• Provision of medicines information

knowledge on discharge

• Develop strategic relationship with

Pharmaceutical Industry partners

Out of Hospital Clinical

Network

Oxford University Hospitals

NHS Trust

Dr Daniel Lasserson • Improving & expanding Out of

Hospital Care models for acute

illness in frail patients

EBHC MSc Fellowship

Programme

University of Oxford Prof Carl Heneghan • Evidence Based Healthcare MSc

Fellowship Programme

Patient Safety Academy University of Oxford Prof Peter McCulloch

Dr Helen Higham

• Development of programmes in

Mental Health & Primary Care

• Training for Trust management staff

• Establishment of the PSA

• Training for Surgical teams

Sustainability Centre for Sustainable

Healthcare

Ms Rachel Stancliffe • Frugal Innovation Fund bid

• Introduce sustainable practice to

everyday considerations

Best Care Oversight Group • Joe Harrison, CEO, Milton Keynes Hospital, Chair • Chandi Ratnatunga, Associate Medical Director, Oxford University Hospitals, Senior

Responsible Owner (SRO) • Tina Kenny Medical Director, Buckinghamshire Healthcare. Medical Lead • Nursing Leads: Catherine Stoddart, Chief Nurse Designate, Oxford University Hospitals

and Helen McKenzie, Director of Nursing, Berkshire Healthcare • David Buckle, Medical Director, NHS Central Southern CSU and Annette Gamel, Chief

Clinical Officer, Chiltern CCG, Clinical Sciences Lead/Allied Healthcare Commissioning Leads

• Sir John Muir Gray, Public Health Lead • Jim Davis, Professor of Software Engineering, University of Oxford, Informatics Lead • Angela Coulter, Senior Research Scientist - Health Services Research Unit,

Independent Advisor • Nigel Edwards CEO, Nuffield Trust, Independent Advisor • Jennifer Dixon (to be confirmed) CEO Health Foundation, Independent Advisor • Paul Durrands COO, Oxford AHSN, Senior Business Lead • Will Pank Best Care Programme Manager, Oxford AHSN

Clinical Networks tackle variation • Significant variation in diagnosis, treatment and health outcomes (eg amputations)

across Oxfordshire

• Our clinical networks are tackling variation, eg in fetal health and diagnosis and treatment of young people with diabetes

Monster Manor - helping children manage their diabetes

Healthy babies for mothers with diabetes – self management

Dr Lucy Mackillop

Prof Tarassenko

Clinical Innovation Adoption The Clinical Innovation Adoption programme has evaluated around 200 innovations taking account of potential benefits, impact on patient experience, local priorities and ease of implementation. A final shortlist of ten, drawn from various sources including the Oxford AHSN clinical networks, local providers, national awards and National Institute for Health and Care Excellence (NICE) Technology Appraisal (TA) recommendations – were approved by the Oxford AHSN Board and are being adopted across our region in 2014/15.

Tracey Marriott, Director of Clinical Innovation Adoption/ Tracey is leading the Clinical Innovation Adoption Programme for the Oxford AHSN, working closely with the Oxford AHSN clinical networks, providers, commissioners and suppliers for innovation implementation.

Higher

Priority

Medium

Priority

Lower

Priority

Review of Oxford AHSN Region NHS Strategic Priorities

Source: NHS Providers Strategic Plans, NHS CCGs Strategic Plans, Joint Strategic Needs

Assessments for Oxfordshire, Buckinghamshire, Berkshire and Bedfordshire

Review of Oxford AHSN Region NHS Strategic Priorities

Clinical Innovation Adoption Ten Innovations for 2014/15

1. CAUTI bladder scanner – reduce urinary tract infections

2. ECG Monitor - moving care closer to home

3. Electronic blood transfusion – patient safety and waste reduction

4. Intermittent pneumatic compression stockings – reduce risk of stroke

5. SHaRON (adults with eating disorders) – better clinical engagement and experience

6. NICE TA - Alzheimer's – improved patient outcome and carer experience

7. NICE TA - Rheumatoid arthritis – improved patient outcome and experience

8. NICE TA - AF, warfarin, anticoagulants - reduce risk of stroke

9. NICE TA - Renal cancer - improved survival

10. Intra operative fluid management - patient safety and recovery

Clinical Innovation Adoption Oversight Group Role Name Title

Chair Anne Eden CEO – Buckinghamshire Health

Senior Responsible Owner (SRO) Best Care Chandi Ratnatunga Consultant Cardiothoracic Surgeon – Oxford University Hospitals

CIA Programme Director Tracey Marriott Director of Clinical Innovation Adoption – Oxford AHSN

Senior Business Lead Paul Durrands Chief Operating Officer – Oxford AHSN

Provider Medical Director Brian Reid Mr Brian Reid – Medical Director – Royal Berkshire Hospital

Provider Director of Nursing Catherine Stoddart Director of Nursing – Oxford University Hospitals

Provider Director of Finance Alex Gild Director of Finance – Berkshire Healthcare

Provider Procurement lead Wayne Preston Director of Finance and Procurement – Buckinghamshire Health

Provider Chief Operating Officer Lisa Glynn Chief Operating Officer – Heatherwood & Wexham Park Hospitals

Commissioner Finance lead Janet Meek Director of Finance, Berkshire West CCG Federation

Commissioner Contract Lead Rebakah Punter Director of Contracting & Procurement Central Southern CSU

Academic Lead Clinical Nursing Practice Susan Procter Clinical Nursing Lead, Buckinghamshire New University

Academic Lead Diagnostics & Primary Care Carl Heneghan Professor and Director of Centre for Evidence Based Medicine, University of Oxford. Also Co-Director Diagnostic Evaluation Collaborative

Academic Lead Innovation Adoption Clive Savory Open University – Communications & System Department

Academic Lead Patient Safety Charles Vincent Professor of Psychology – Department of Experimental Psychology

Oxford AHSN Medicines Optimisation Network Lead

Bhulesh Vadher Chief Pharmacist – Oxford University Hospitals

Senior Lecturer Marketing and Course – Leader PR & MarCom

Bill Nichols Director – Centre for Health Communications Research Buckinghamshire New University

Prof Gary A Ford CBE is Chief Executive Officer of the Oxford AHSN. Gary has led the adoption of innovation in stroke care for many years. He remains a practising clinician as a Consultant Stroke Physician at Oxford University Hospitals NHS Trust. He is also Director of the National Institute for Health Research (NIHR) Stroke Research Network.

• Brought together leads from Universities and NHS partners

• NHS partners to each develop R&D strategies

• Grow commercial research base and income across the NHS Trusts

• Close links with Clinical Research Network (LCRN) and the Collaboration for Leadership in Applied Health Research and Care (CLAHRC)

• Cross working with the Oxford Academic Health Science Centre (AHSC) – one of 6 leaders in research

Research & Development

Big Data: Delivering the Digital Medicine

Revolution

Building Novel NHS, University

and Industry Relationships

Modulating Immune

Response for Patient Benefit

Managing the Epidemic of

Chronic Disease

Emerging Infections &

Antimicrobial Resistance

Cognitive Health:

Maintaining Cognitive

Function in Health and

Disease

AHSC priorities

Oxford Academic Health Science

Centre - world leading

research in healthcare and life

sciences

Research and Development Oversight Group

University Research lead/alternate

Chairman Sir Jonathan Michael University of Oxford Professor Alastair Buchan

University of Reading Dr Ben Whalley Buckinghamshire New University Professor Susan Procter The Open University Dr Nacho Romero / Dr Claire Turner The University of West London Professor Heather Loveday/Dr Jennie Wilson

Oxford Brookes University Professor Linda King (Mary Boulton/Helen Dawes) University of Buckingham Professor Mike Cawthorne

University of Bedfordshire Professor Mike Cook/ Professor Mike Fisher Cranfield University TBC

Oxford University Hospitals Prof Keith Channon

Oxford Health Prof John Geddes Berkshire Healthcare Dr Justin Wilson Heatherwood and Wexham Park Dr Rob Loveland

Royal Berkshire Dr Atul Kapila South Central Ambulance Service Mr Will Hancock/John Black

Central and North West London Dr Alex Lewis Milton Keynes Mr Martin Wetherill Great Western Dr David Collins Buckinghamshire Healthcare Dr Matthew Burn Bedford Hospital Dr Colette Marshall Southern Health Dr Helen McCormack Health Education Thames Valley/Oxford University Clinical Academic Graduate School

Professor Chris Pugh

South Midland and Thames Valley Clinical Research Network Dr Belinda Lennox

Collaboration for Leadership in Applied Health Research Professor Richard Hobbs/Dr Belinda Lennox

Wealth Creation

Dr Nick Scott-Ram MBE, Director of Commercial Development, has over 25 years experience in commercial and business development in the life sciences sector. Nick was awarded the MBE for services to biotechnology in 2001.

The Wealth Creation Programme will help the region become the favoured location for life science investment, life science business creation and growth, helping the NHS – through the Oxford AHSN’s Clinical Networks – to accelerate the adoption of proven innovations which will bring significant benefit to patients. The Oxford AHSN wealth creation strategy is for, and on behalf of, our member organisations – the NHS, Local Enterprise Partnerships (LEPs), Universities and industry – and the population who all share an interest in economic growth across the region.

Oxford AHSN Wealth Creation

Types of Medical Innovation Any new product or service that delivers benefit to patients

• Pharmaceuticals – New drugs or new uses for established drugs

• Vaccines

• ATMP (Advanced Therapy Medicinal Products) – Gene or cell therapies

• Tissue engineered products and regenerative medicine

• Surgical innovations

• Medical diagnostics and devices

• Information Technology, medical informatics, mHealth and eHealth

• Clinical decision making and support including IT tools to support compliance with best practice

• Healthcare delivery, management and administration

• Health promotion & disease prevention and patient driven wellness (public health)

Outbound Innovation

Helping to ensure that great ideas from

the NHS, universities and industry are

converted into products and services

that create value for patients within and

beyond our region

Inbound Innovation

Informing the NHS about high value

innovations and enabling staff to make

full use of them to improve outcomes

and experiences of patients

Wealth Creation Initiatives in Oxford AHSN region

• The Structural Genomics Consortium • Open access partnerships with the pharmaceutical industry

• The Oxford BioEscalator • Facilitating new models for business growth

• Target Discovery Institute • Link genomics, cell and chemical biology for improved drug discovery

• Centre of Excellence in Personalised Healthcare • Institute of Biomedical Engineering

• University of Reading Science and Innovation Park • £50 million investment in site infrastructure and Phase I

• Phase I – 150,000 – 200,000 sq.ft.

Wealth Creation - create a system to support key stakeholders

• Large companies • Helping identify opportunities for joint working / acquisitions of start ups

• Helping them engage with the NHS

• Innovators / entrepreneurs • Need to know how to get started, how to get help, how to get funding

• Many of these will be from University / NHS

• SBRI working with the other AHSNs

• Helping them engage with the NHS

• Investors • Facilitating the search for investments within the areas of interest

• Improved information provision and "marketing" of investment opportunities in the region

• Experienced entrepreneurs / business people • Connecting with, investing in and supporting start-ups in the region

• Infrastructure providers (LEPs, Isis & others) • Recognising what is needed from them and ensuring that have aligned strategies for

investment

Wealth Creation - building alignment

Category Benefit

Academia Innovation commercialisation and adoption

Clinicians Improved industry engagement and innovation commercialisation

Industry Improved engagement with clinicians, academics, providers; opportunities to commercialise and improved innovation adoption

Patients & Public Improved engagement with clinicians and providers and opportunities to participate in research

Providers Improved engagement with academics and industry

Wealth Creation - benefits for industry

• Better engagement with clinicians, providers and patients / public • Builds a clearer understanding of clinical, provider & patient behaviours

• Improved approach to adoption, by providers, of innovation at scale • Adoption and methods of care assessed in a systemic fashion across the system rather

than by top down imposition or ad hoc local adoption

• Understanding of large strategic changes • Shift to out of hospital care, integrated care

• Opportunities to work with innovators to commercialise their innovations

• New technologies can act as catalyst for change across care pathways which leads to patient benefit

Wealth Creation - emerging themes • Exploring new opportunities for investment vehicles within the region

• MedTech and e-health

• Building a culture of innovation in the NHS • Supporting entrepreneurship – boot camp • Challenge 2023 • Clinical consultancy for businesses • Sustainability – opportunity assessment for HEIs and Trusts on carbon reduction

• Building sustainable businesses that can grow to significant mid-cap opportunities

• Exploring new types of multi-party agreements that enhance co-operation, increase probability of success within a pre-competitive and competitive environment

• Structural Genomics Consortium – disease specific late stage development • University of Reading – flavonoids and improvement of cognition

• Ensuring that the NHS can deliver in terms of innovation adoption, thereby supporting new innovative businesses – key dependency on the Clinical Innovation Adoption programme

Wealth Creation - Apps and e-health Lab • Commissioned App Development Roadmap

• Oxford e-health Lab – multi-partner coordinating hub for e-health activity and acceleration of innovation and implementation

• Local App examples: • AED Locator (find a defibrillator)

• Foodswitch – calorie and salt control

• Monster Manor – blood sugar control for children with Type 1 Diabetes

Wealth Creation - Oversight Group is aligned to the LEPs

Wealth Creation Oversight Group

Berkshire Working Group for Wealth

Creation

Buckinghamshire Working Group for

Wealth Creation

Oxfordshire Working Group for

Wealth Creation

Wealth Creation Oversight Group Role Name Title

Chair Dr Nicholas Edwards Chairman MedInnovate

Internal Dr Nick Scott-Ram MBE Director of Commercial Development – Oxford AHSN

Internal Professor Chas Bountra Professor of Translational Medicine, Head of Structural Genomics Consortium

External Dr Martino Picardo Chief Executive Officer – Stevenage Bioscience Catalyst

External Dr John Collins Chief Operating Officer and Technology Implementation Director – Center for Integration of Medicine and Innovative Technology (CIMIT, Boston, Mass)

External Mr Joel Haspel (Invited) Oracle

External Berkshire Working Group Chair (1)

TBA

External Buckinghamshire Working Group Chair

TBA

External Oxfordshire Working Group Chair

TBA

(1) The working groups have been aligned to the Local Enterprise Partnership geographies to better support inward investment

Informatics

Mike Denis, Director of Information Strategy and Governance, has a dual role across the Oxford AHSN and Oxford AHSC and provides strategic leadership in linking core business goals through informatics and technology innovation, whilst providing critical contribution to the Oxford AHSN and Oxford AHSC partners’ strategies Informatics is a cross-cutting theme, linking core business goals through technology innovation, both within the Oxford AHSN and with partner organisations Informatics map out requirements and establish a common information sharing agreement. We help to facilitate patient recruitment to research studies and clinical trials and extend programme research databases across organisations in primary, community and acute services

Mike Denis, Director of Information Strategy, has over 26 years experience working in NHS health informatics. He previously held a similar role at the South London and Maudsley NHS Foundation Trust.

Patient and Public Involvement, Engagement

and Experience (PPIEE)

Dr Sian Rees is the lead for Patient and Public Involvement, Engagement and Experience, working with colleagues in Trusts across the Oxford AHSN area, and the NHS England Area Team, Health Education Thames Valley and the CLAHRC. In particular, she will support this area of activity in each of the developing clinical networks.

The Oxford AHSN is working to embed partnership with patients and the public across its work programmes. Each of the clinical networks is developing plans for PPIEE. PPIEE Theme is a joint production with the Thames Valley Local Area team and Health Education Thames Valley

What do we mean by involvement? How patients and the public will be involved in the structures and processes of the work i.e though mechanisms such as governance, priority setting, teaching and education, identification of the need for innovation, assessment of technologies. What do we mean by engagement? How patients and their carers will be supported to be active participants in their own care through approaches such as personalised care planning and shared decision-making. What do we mean by experience? How the subjective experience of patients is captured and utilised for quality improvement.

Contact details: Megan Turmezei

Director of Corporate Affairs

Oxford AHSN

John Eccles House

Robert Robinson Avenue

OXFORD SCIENCE PARK

OX4 4GP

Megan.turmezei@ouh.nhs.uk

Megan.turmezei@oxfordahsn.org

T: 01865 338425

M: 07837 401519

www.Oxfordahsn.org

Newsletter: http://www.oxfordahsn.org/news-and-

events/network-newsletters/

Annual report: http://www.oxfordahsn.org/wp-

content/uploads/2014/06/Oxford_AH

SN_Annual_Report_2014.pdf