gastrointestinal disorders
DESCRIPTION
Immense research on Gastrointestinal disorders is seen due to its prevalence in majority countries in the world. thus its essential to understand how to tackle with it through natural medicine to avoid side effects of alopathyTRANSCRIPT
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Presented by Dr. Sudhakar KokateDirector PPRC, India
Plantsthat cure
Gastro Intestinal disorders(GID – Part I)
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Gastro-intestinal disorders (GID)
Include :Colitis
Constipation
Diarrhoea
Duodenal ulcers
Dyspepsia
Hyper-acidityPPRC/INDIA 01
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In India
Plant species: 9500 Medicinal: 7500 Tribal medicinal plants: 300 For G.I. Disorders:
Bael Isabgol KurchiPale catechu Palas GingerShatavari Mandar Carrot
PPRC/INDIA 02
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Around the World
Mexico: 65 plants to treat G.I. disorders(GID)
Thailand: 38 plants for GID Germany / France: Many herbs used as
prescription drug (Sale > $ 50bn……2010)
USA: $ 4 bn……1996 India: Drug market $1bn export of plant
crude drugs $ 80 mn PPRC/INDIA 03
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Knowledge of Medi-plants
Dates back to 400 B.C.
First documented in Atharva Veda datesback to 4500-1500 B.C.
119 compounds with therapeutic valuehave been identified till date
Japanese pharmacopoeia 1993 contains123 active plants of which 29 are used inWestern medicine
PPRC/INDIA 04
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Aconitum heterophyllum
PPRC/INDIA 05
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Aconitum heterophyllum Habitat: Eastern Asia, Western Himalaya
Chemicals:- Astisine- Hetratisine- Histsine- Benzoyl-heterophyllum
It is employed in as a bitter tonic andanti-periodic
PPRC/INDIA 06
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Aegle marmelos
PPRC/INDIA 07
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Aegle marmelos Habitat: India, China, Sri Lanka, Burma,
Thailand
Chemicals:
Leaves: Alkaloid, Agelin, Sterol as V-sitosterol and Coumarins, Essential oilssuch as d-limonene
Bark: Aegelinin, Marmin
PPRC/INDIA 08
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1/22/2014
Aegle marmelos Chemicals:
Fruit: Sugar, Tannin
Pulp: 2 furocoumarins-psoraen andMarmelosin
Properties: Astringent, Depurative,Alexeteric, Cooling, Anti-poison
PPRC/INDIA 09
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Amphipterygium adstringens
PPRC/INDIA 10
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Amphipterygium adstringensMost gastro-protective compounds:
3 epi-oleanolic acid
3 alpha-hydroxy mastica dienonic acid
Beta-sitosterol acid
PPRC/INDIA 11
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Arnica montana
PPRC/INDIA 12
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Arnica montana The plant is rich in Sesquiterpenes
It has advantage in states of depression,diarrhoea, dysentery, pneumonia, typhoidand excessive sweating
PPRC/INDIA 13
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Asparagus adscendens
PPRC/INDIA 14
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Asparagus adscendens Habitat: India – forests of Uttar Pradesh,
East Asia, Afghanistan, Himalayas, Iran
Chemical: Asparagine
Roots: Demulcent, Diaphoretic,Galactogogue, Stimulant are useful in thetreatment of Diarrhoea and dysentery
PPRC/INDIA 15
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Calotropis gigantea
PPRC/INDIA 16
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Calotropis gigantea Habitat: Sub-tropic & Tropic, India, Sri
Lanka, West Indies
Active principles: Saponins, Glucoside,Tannins, Lugeol, Flavonoids, Glycine,Butrin, Isobutrin, 3-o acetyl-calotropin
Root Bark extensively used for GID
PPRC/INDIA 17
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Coriandrum sativum
PPRC/INDIA 18
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Coriandrum sativum Coriander seed oil has anti-bacterial
property and is used for treating colic,neuralgia, rheumatism, diarrhoea,hemorrhoids, flatulence and abdominalpains
PPRC/INDIA 19
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Curcuma longa
PPRC/INDIA 20
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Curcuma longa Active principle: Curcumin
diferuoylemethane
PPRC/INDIA 21
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Daucus carota
PPRC/INDIA 22
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Daucus carota Chemicals: Lutenolin-7-glucoside,
Mevolonic acid, Pyrolidine daucine &Essential oils
Used in stomach & intestinal problems
Carrot soup remedy for diarrhoea
Properties: Anthelmintic, Carminative,Diuretic and Stimulant
PPRC/INDIA 23
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Eugenia jambolana
PPRC/INDIA 24
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Eugenia jambolana Seed powder effective in diarrhoea,
dysentery and diabetes
Habitat: India, Queensland
Chemicals: Oleanolic acid, Glucosideshowed significant reduction & G.I.motility
Fruit: Astringent, Stomachic, Carminative,Diuretic, Spleen enlargement, Chronicdiarrhoea & Urine retention PPRC/INDIA 25
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Helicteres isora
PPRC/INDIA 26
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Helicteres isora Chemicals:
- Phytosterol
- Hydroxy-carboxylic acid
- Phytolobotannins
Effective against G.I. disorders
PPRC/INDIA 27
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Melissa officinalis
PPRC/INDIA 28
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Melissa officinalis In Germany, Lemon balm is used as a
medicinal tea to treat G.I. disorders
Chemicals: 0.05% Volatile oil, Rosemaryacid
PPRC/INDIA 29
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Ocimum sanctum
PPRC/INDIA 30
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Ocimum sanctum Phyto-chemicals: Essential oils, Eugenol,
Methyl ether, Terbinene-4-01, Spigennins,Apigenin-7-0-glucuronide
Pharmacological action: Hypotensiveactivity, Inhibition of smooth musclecontraction induced by Acetylcholine,Carbachol and Histamine
PPRC/INDIA 31
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Pueraria lobata
PPRC/INDIA 32
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Puerata lobata In China, Japan; leaves, roots and shoots
are used for treating Alcoholism, Coldflu, G.I. disorders
Flowers and tubers are used for treatingFever, Cold, Diarrhoea, Dysentery andAcute intestinal ailments
PPRC/INDIA 33
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Phyto-drugs* for curing G.I. Disorders
Drugs/Chemical Plant used
Aesculetin Frazinus rhychophylla
Andrographolide Andrographis paniculata
Berberine Berberis vulgaris
Hemsleyadin Hemsleya amabilis
Neoandrographolide Andrographis paniculata* Commercial PPRC/INDIA 34
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Thank You !!