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Mandarin Ducks (Aix galericulata) are frequently featured
in Chinese art and are regarded as a symbol of fidelity.
Fidelity atits finest.Q5™ High-Fidelity
DNA PolymeraseQ5 High-Fidelity DNA Polymerase sets a new
standard for both fidelity and performance. With
the highest fidelity amplification available (>50X
higher than Taq), Q5 DNA Polymerase results
in ultra-low error rates. Its unique buffer system
provides superior performance for a broad range
of amplicons, regardless of GC content. Available
in master mix and hot start formulations, Q5 DNA
Polymerase represents the finest in fidelity.
For more information, including our
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Robust amplification even with high GC amplicons
Amplification of two human genomic amplicons of mid to high GC content.All reactions were conducted using 30 cycles of amplification and visualizedby microfluidic LabChip® analysis. All polymerases were cycled according tomanufacturer’s recommendations. For the 78% GC amplicon, GC Buffers orenhancers were used when supplied with the polymerase.
A = Q5™ High-Fidelity DNA Polymerase (NEB)B = Phusion® High-Fidelity DNA Polymerase (NEB)C = KOD DNA Polymerase (EMD)D = PfuUltra™ High-Fidelity DNA Polymerase (Agilent)
60% GC 78% GC
490029001900
1100
700
500
300
bp L A B C D A B C D
PHUSION® is a registered trademark and property of Thermo Fisher Scientific.
Phusion® DNA Polymerase was developed by Finnzymes Oy, now a part of Thermo Fisher Scientific.
PFUULTRA™ is a trademark of Agilent Technologies, Inc.
LABCHIP® is a registered trademark of Caliper Life Sciences, part of Perkin Elmer, Inc.
Q5™ is a trademark of New England Biolabs, Inc.
ALSO AVAILABLE: Optimized NEBNext® formulation
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eppendorfÆ, Eppendorf PhysioCare ConceptÆ, PhysioCare ConceptÆ and Eppendorf XplorerÆ
are registered trademarks and Eppendorf Xplorer plus is a trademark of Eppendorf AG.
All rights reserved incl. graphics and photos. Copyright © 2012 by Eppendorf AG.
Eppendorf XplorerÆ and Eppendorf XplorerÆ plusóthe electronic pipettes
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Launched in March 2012,
Science & Diplomacy
provides an open access forum
for rigorous thought, analysis,
and insight to serve stakeholders
who develop, implement, and
teach all aspects of science
and diplomacy. Learn more
about the latest ideas in
science diplomacy and
receive regular updates by following
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Science & Diplomacy is published by the Center for Science
Diplomacy of the American Associa�on for the Advancement of
Science (AAAS), the worldís largest general scien�ˇc society.
FOCUS ON CAREERS
Faculty
Produced by the Science/AAAS Custom Publishing Office
In This IssueThe science of biology is one thing but the science of business
is another animal all together. For academics who recognize that
their discovery or innovation can be commercialized into a prod-
uct or service for which people will actually pay, the promise of
entrepreneurial endeavors can be exhilarating and confounding at
the same time. Issues of intellectual property ownership, human
resources protocols, and time management, as well as the chal-
lenge of keeping a delineated barrier between profes-
sorial and business activities can be dif�cult to
manage, but these concerns shouldn�t prevent
academics from seeking to create a startup
company. The key is to �nd avenues to bal-
ance the two worlds so that scientists can
still continue to excel in what they do best
and enjoy most�research and discovery.
See full story on page 1368.
Upcoming Features
Top Employers Survey�September 21 (online); October 19 (print)
China Regional Focus�September 28
European Regional Focus�November 9
Finding Balance:The Professor/Entrepreneur
PERSONAL LAB STERILIZER
The CoolCLAVE is a compact, easy-to-use personal lab sterilizer which uses ozone gas to clean
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1365www.sciencemag.org/products SCIENCE VOL 337 14 SEPTEMBER 2012
Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are
featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or
materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.
Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.
Produced by the Science/AAAS Custom Publishing Office
ELONGATED TIPS
Combitips Advanced offer safe, accurate dispensing of liquids by
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WATER PURIFICATION SYSTEMS
The new AFS 8D and AFS 16D water puri� cation systems are de-
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EMD Millipore
For info: 800-645-5476 www.millipore.com
VISIBLE-NIR LIGHT SOURCEThe new high-power Model 610 includes a powerful 650 W quartz
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The McPherson Model 610 is useful for visible-near infrared (VIS-
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McPherson
For info: 978-256-4512 www.mcphersoninc.com
CRYO-SEM PREPARATION SYSTEMThe PP3000T is a highly automated, easy-to-use, column-mounted,
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For info: 215-412-8400 www.emsdiasum.com
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THE TRANSLATIONAL
SCIENCE OF RARE DISEASES:
FROM RARE TO CARE
October 8-10, 2012
Palais de Lichtenstein
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For more information, including a fulllist of speakers, visit dmm.aaas.org.
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