framework use in clinical research

6
RE- AIM Reach Efficacy Advocate Implement Maintenance Framework Use in Clinical Research

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Page 1: Framework Use in Clinical Research

RE-AIM

Reach

Efficacy

Advocate

Implement

Maintenance

Framework Use in Clinical Research

Page 2: Framework Use in Clinical Research

Theory vs. Model vs. Framework: Nilsen

• Theory: principles, statements to explain things of the world; explanatory and descriptive

• Model: a narrowed theory; descriptive• Framework: structure, overview, outline of descriptive

categories

Page 3: Framework Use in Clinical Research

Pre-RE-AIM

• Impact of interventions

• I = R * E

• Missing aspects public health impact

• Did not take setting into consideration

Page 4: Framework Use in Clinical Research

Nilsen, P 2015

Page 5: Framework Use in Clinical Research

RE-AIM

• Reach: Individual level measurement; participation out of population

• Efficacy: Biological, behavioral outcomes, and QOL to measure success

• Adoption: representation in the settings• Implementation: individual (adherence) and setting

(protocol deviations)• Maintenance: post study sustainability

Page 6: Framework Use in Clinical Research

RE-A

IM 1

999- Public Health

- Evaluation- All 5 are equally important but may be weighted differently- Internal/External validity- Individual interventions

Over

time- Used in planning,

progress, report results- Used outside of public health- Confusion over term use- Not all dimensions used