four score validity
DESCRIPTION
validity of four score in ICU settingTRANSCRIPT
Vivek N. Iyer, MD; Jayawant N. Mandrekar, PhD; Richard D. Danielson, RN;Alexander Y. Zubkov, MD, PhD; Jennifer L. Elmer, RN; and Eelco F. M. Wijdicks, MD, PhD.
Validity of the FOUR Score Coma Scale in the Medical Intensive
Care Unit
Objective
To evaluate the validity of the FOUR score (ranging from 0-16), a new coma scale that consists of 4 components (eye response, motor response, brainstem reflexes and respiration pattern) when used by ICU members.
Patients and Methods
100 critically ill patients were observed for interobserver agreement, comparison by using FOUR score and GCS score.
Observer are randomly assigned to pair (nurse/fellow, nurse/consultant, fellow/fellow, or fellow/consultant)
Result
Interobserver agreement with the FOUR score was excellent (similar to GCS).
In terms of predictive power for poor neurologic outcome, FOUR score is similar to GCS.
Mortality rate for patients with the lowest score is higher with the FOUR score (89%) than GCS (71%)
Conclusion
Interobserver agreement of FOUR score was excellent.
In contrast to GCS, all components of FOUR score can be evaluated in intubated patients.
FOUR score is a good predictor of the prognosis of critically ill patients.
FOUR score has important advantages over the GCS in ICU setting.
Description of FOUR Score
4 components : Eye response Motor response Brainstem reflexes Respiratory pattern
Eye Response
Motor Response
Brainstem Reflexes
Respiratory Pattern
Outcome Assessment
Morbidity was assessed at 3 months with Modified Rankin Scale
0 -> no symptoms1 -> no evident disability, symptoms (+)2 -> slight disability, ADL disturbance (-)3 -> moderate disability, need some help but able
to walk without assistance.4 -> moderately severe disability, unable to walk
without assistance.5 -> severe disability, bed ridden, incontinent,
require constant caring6 -> death
Statistical Analysis
Pairwise weighted k valuesOverall weighted k valuesIntraclass correlation
Cornbach α calculated for assessment of internal consistencySpearman correlation calculated between FOUR score and GCS score
Calculated for FOUR Score and GCS Score
Result
FOUR SCore
FOUR Score
Glasgow Coma Scale
FOUR Score
Glasgow Coma Scale
Cont...
High degree of internal consistency for both FOUR and GCS
For every 1 –point increase in the total FOUR Score, the odds of in- hospital mortality were reduced 15%, poor neurologic outcome was reduced 18% (comparable to GCS)
8 of 9 patient with lowest FOUR score died (89%)
15 of 21 patients with lowest GCS score died (71%)
Discussion
The level of interobserver agreement found in the current study was slightly higher than that found by the first validation study
An ideal coma scale would be reliable,valid, linear and easy to use
The GCS has a number of shortcomings,the verbal component. It could not reliably assesed in 45 of the 100 patients in the study
Cont....
The FOUR score aims to overcome these shortcomings because it is both simple to use and comprehensive.
The FOUR score can be easily used in ICU settings
The FOUR score accurately predicts poor outcome,detect braindeath, and diagnose a locked-in syndrome
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