foot and mouth disease in the uk (surrey) · key - range of uncertainty in age of lesions - most...
TRANSCRIPT
2
Agenda
• Information as at 17:00 17 Oct 2007• History of 8 IPs and epidemiology• Additional measures• Surveillance• Domestic movement controls
5
August cluster
• 3 Aug: IP1 (3 locations)• 6 Aug: IP2 (3 locations)• Virus only found at 1 location in each case• 3 contact herds culled• 24 Aug: PZs lifted• 8 Sep: SZ lifted• Origin: contamination from Pirbright site• Virus: O1 BFS
7
September ClusterConfirmation dates
• IP3, 12 Sep• IP4, 13 Sep • IP5, 17 Sep• IP6, 21 Sep• IP7, 24 Sep• IP8, 30 Sep
9
InfectionTim
eline –Septem
ber Cases
Day of outbreak
23
45
67
89
910
1112
1314
1516
1718
1920
2122
2324
2526
2728
2930
3132
3334
3536
3738
3940
4142
4344
4546
4748
4950
5152
5354
5556
5758
59D
ay of outbreak
Date
04/08
05/08
06/08
07/08
08/08
09/08
10/08
11/08
12/08
13/08
14/08
15/08
16/08
17/08
18/08
19/08
20/08
21/08
22/08
23/08
24/08
25/08
26/08
27/08
28/08
29/08
30/08
31/08
01/09
02/09
03/09
04/09
05/09
06/09
07/09
08/09
09/09
10/09
11/09
12/09
13/09
14/09
15/09
16/09
17/09
18/09
19/09
20/09
21/09
22/09
23/09
24/09
25/09
26/09
27/09
28/09
29/09
30/09
01/10
Date
Day
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Day
Source w
indow
for IP4B
Source w
indow for
IP4B
Day 0 IP
4BD
ay 0 IP4B
Spread w
indow
for IP4B
Spread w
indow for
IP4B
Source w
indow
for IP4B
Source w
indow for
IP4B
Day 0 IP
4BD
ay 0 IP4B
Spread w
indow
for IP4B
Spread w
indow for
IP4B
Source w
indow
for IP3B
*S
ource window
for IP
3B
Day 0 IP
3B*
Day 0 IP
3B
Spread w
indow
for IP3B
*S
pread window
for IP
3B
Source w
indow
for IP3C
Source w
indow for
IP3C
Day 0 IP
3CD
ay 0 IP3C
Spread w
indow
for IP3C
Spread w
indow for
IP3C
Source w
indow
for IP6B
Source w
indow for
IP6B
Day 0 IP
6BD
ay 0 IP6B
Spread w
indow
for IP6B
Spread w
indow for
IP6B
Source w
indow
for IP7
Source w
indow for
IP7
Day 0 IP
7D
ay 0 IP7
Spread w
indow
for IP7
Spread w
indow for
IP7
Source w
indow
for IP8B
Source w
indow for
IP8B
Day 0 IP
8BD
ay 0 IP8B
Spread w
indow
for IP8B
Spread w
indow for
IP8B
Day of outbreak
23
45
67
89
910
1112
1314
1516
1718
1920
2122
2324
2526
2728
2930
3132
3334
3536
3738
3940
4142
4344
4546
4748
4950
5152
5354
5556
5758
59D
ay of outbreak
Date
04/08
05/08
06/08
07/08
08/08
09/08
10/08
11/08
12/08
13/08
14/08
15/08
16/08
17/08
18/08
19/08
20/08
21/08
22/08
23/08
24/08
25/08
26/08
27/08
28/08
29/08
30/08
31/08
01/09
02/09
03/09
04/09
05/09
06/09
07/09
08/09
09/09
10/09
11/09
12/09
13/09
14/09
15/09
16/09
17/09
18/09
19/09
20/09
21/09
22/09
23/09
24/09
25/09
26/09
27/09
28/09
29/09
30/09
01/10
Date
Day
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Mon
Day
KE
Y- range of uncertainty in age of lesions
- most likely source w
indow
- range of uncertainty in source window
- most likely day zero date
- range of uncertainty in spread window
- most likely spread w
indow
*N
ote: On IP
3B, 28 out of 29 cattle found to be negative on serology. T
herefore, expert opinion confirms that lesions ages m
ust be five days or less.N
ote: Expert opinion on IP
7 confirms age of lesions at 5 days
Note: IP
8 date of 1st lesions (Wednesday 26 S
eptember 2007) aw
aiting final confirmation from
IAH
Pirbright staff.
PS
= Pirbright site
IP3
IP 4IP 3
IP4 IP5
IP 5
IP6BIP7
IP6BIP7
IP8B
IP8B
IP4B
day
0IP
4B m
ost likely spread window
30/08 to 15/09
IP3B
most likely source w
indow
24/08 to 05/09IP
3B
Day
IP3B
most likely spread w
indow
06/09 to 14/09
IP4B
most likely source w
indow20/08 to 01/09
IP3C
source window
26/08 to 07/09IP
3C
Day
IP3C
most likely spread w
indow08/09 to 16/09
IP5
day 0
IP5 m
ost likely spread window
12/08 to 21/09
IP5 m
ost likely source window
06/08 to 18/08
IP6B
D
ay
IP6B
most likely spread w
indow16/09 to 23/09
IP 7
Day
IP6B
source window
03/09 to 15/09
IP7 source w
indow05/09 to 17/09
IP7 m
ost likely spread window
18/09 to 25/09
IP8 m
ost likely spread window
25/09 to 01/10
IP 8
Day
IP8 source w
indow12/09 to 24/09
10
Clinical disease on each IPDistribution of Day 0 lesions on all IPs
IP1
IP1
IP1
IP1
IP1
IP1
IP1
IP1
IP2
IP2
IP2
IP2
IP2
IP2
IP2
IP2
IP5
Shee
p
IP5
Cat
tle IP5
Cat
tle
IP5
Cat
tle
IP4B
IP4B
IP4B
IP4B
IP4B
IP4B
IP3B
IP3B
IP3B
IP3B
IP3B
IP3B
IP3C
IP3C
IP7IP7 IP7
IP7IP7IP6B
IP6B
IP8
0
2
4
6
8
10
12
14
16
18
20
25.7.
0727
.7.07
29.7.
0731
.7.07
2.8.07
4.8.07
6.8.07
8.8.07
10.8.
0712
.8.07
14.8.
0716
.8.07
18.8.
0720
.8.07
22.8.
0724
.8.07
26.8.
0728
.8.07
30.8.
071.9
.073.9
.075.9
.077.9
.079.9
.0711
.9.07
13.9.
0715
.9.07
17.9.
0719
.9.07
21.9.
0723
.9.07
25.9.
0727
.9.07
Date
Num
ber o
f ani
mal
s w
ith D
ay 0
lesi
ons
IP1 IP2 IP5 Sheep IP5 Cattle IP4B IP3B IP3C IP7 IP6B IP8
11
Infected Premises 5
• Detected 16 September. No acute signs.• 17 out of 22 cattle with 4-5 week old lesions.
All seropositive, virus negative.• 15 out of 16 sheep seropositive; 10 with old
lesions. • 2 pigs – no lesions; seronegative, virus
negative.• Confirmed 17 September. Single location.
12
Links between IPs
PIRBRIGHT
FACILITIES20 Jul
to
08 Aug
IP2Infectious from
27 Jul to
09 Aug
IP3BInfectious from
06 Sep to
14 Sep
IP4BInfectious from
02 Sep* to
15 Sep
IP3CInfectious from
08 Sep to
16 Sep
IP1Infectious from
22 Jul to
09 Aug IP5Infectious from
19 Aug* to
21 Sep
IP6BInfectious from
15 Sep to
23 Sep
IP7Infectious from
18 Sep to
25 Sep
IP8BInfectious from
25 Sep to
1 Oct
13
Additional Culling
• 160 cattle + 1 goat on 4 holdings(5 locations) within 3km of IP8
• Likely to be exposed to infection and incubating disease
• Laboratory tests negative
18
100%ESA 4
97%ESA3b
100%ESA 3a
100%ESA 2
100%ESA 1
% Visits completedEnhanced Surveillance Area
Enhanced Surveillance
20
Report cases of Suspect FMD
As of 12:00, 18 October
• Confirmed: 8• Negated: 197• Under investigation: 1
Total: 208
24
Abattoir surveillance
Intensified AME & PME (August-September)
– 347,656 cattle– 2,495,320 sheep– 1,336,396 pigs– 8,162 deer– 862 goats
25
Clinical Inspections at welfare visits (as at 11 October)
• 283 groups of animals on-farm• 235 groups of animals at markets
28
Developments this week
17 October• PZ surveillance completed and lifted • Restricted zone reduced to ‘8 counties’
30
Summary
• 8 IPs, 2 clusters in Surrey. Very low risk that infection has spread outside this area
• Unlikely that contaminated meat or other products are in circulation
• Intensive surveillance well beyond minimum requirements of Directive
• Over 12 000 surveillance samples tested with negative results (except sheep on IP5)
• Tracings from IPs, PZs, SZs negative• Nationwide monitoring through report cases,
abattoirs, welfare and licensing inspections.