foodintolerance - sinseb.it · case report –motogp rider terapy: ‐diet(foodintolerance)...
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Colazione ......................................................... 706 KcalAcqua, appena sveglio2 cucchiai di mieleSuperscodella di mueslilatte di mandorle o di riso non zuccherato
Spuntino di metà mattina (se necessario) .......... 488 KcalPane o crakers senza glutineavocado e tonno
Pranzo ................................................................. 440 KcalInsalata mistaPasta primavera senza glutine
Merenda ............................................................. 316 KcalMela con burro di anacardiMelone, anguria o simili
Cena ..................................................................... 880 KcalInsalata Caesar con cavolo nero e quinoaMinestroneSalmone alle erbe ________
2830 Kcal
DIAGNOSI: TEST GENETICO
Popolazione
DQ2 – DQ8
Celiaci
90‐95% DEI PAZIENTI AFFETTIDA MALATTIA CELIACA E’ POSITIVA PER HLA‐DQ2
1‐2% DELLE PERSONE CON HLA‐DQ2 COMPATIBILE CON LA CELIACA SVILUPPERA’ LA MALATTIA
Transglutaminasi
ID DQ2 DQ8IgA
< 10 U/mLIgG
< 50 U/mLIgA IgG
IgA < 10 U/mL
Intolleranza frumento (ALCAT)
1 DQA1*050 NO 6,5 15,4 < 1/5 < 1/10 3,8 22 DQB1*0201 NO 4,3 43,7 < 1/5 < 1/10 2,6 03 DQA1*050 NO < 3 < 3 15,1 04 DQ2 NO < 3 < 3 2,7 05 DQA1*050 NO < 3 < 3 4 06 NO NO 1,6 12,1 < 1/5 < 1/10 3,8 17 DQA1*050 NO 2,1 85,9 < 1/5 < 1/10 3 28 DQ2 DQ8 0,6 14,2 < 1/5 < 1/10 2,9 09 DQ2 NO 1,2 3,5 < 1/5 < 1/10 4,1 110 DQ2 NO 2,4 4,3 < 1/5 < 1/10 2,9 111 DQ2 NO 3,1 4,6 < 1/5 < 1/10 2,5 112 DQA1*050 NO < 3 < 3 3,5 013 DQ2 DQ8 3,1 3,3 < 1/5 < 1/10 3,8 014 DQB1*0201 NO < 3 < 3 3,2 215 DQ2 NO 2,6 16,3 < 1/5 < 1/10 3,8 216 DQ2 NO 3,1 62,3 < 1/5 < 1/10 2,7 217 DQA1*050 NO 6,7 33,2 < 1/5 < 1/10 4,9 118 DQ2 NO 4,2 43,0 < 1/5 < 1/10 9,7 019 DQ2 NO 0,4 16,0 < 1/5 < 1/10 10,2 220 DQ2 DQ8 2,9 81,2 < 1/5 < 1/10 5,6 121 DQ2 NO 3,5 4,0 < 1/5 < 1/10 2,3 122 DQ2 DQ8 1,1 3,0 < 1/5 < 1/10 3,3 123 DQA1*050 NO 1,3 43,3 < 1/5 < 1/10 4,5 224 DQA1*050 NO 0,4 5,4 < 1/5 < 1/10 3,7 325 DQB1*0201 NO 2,1 6,7 < 1/5 < 1/10 3,7 226 DQB1*0201 NO < 3 < 3 3 027 DQ2 DQ8 0,6 3,5 < 1/5 < 1/10 2,4 1
Anti Gliadina Anti Endomisio
1 Intolleranza Lieve2 Intolleranza Moderata3 Intolleranza Marcata
CELIAC DISEASE: GENETIC, MARKERS CHEMISTRY & FOOD INTOLERANCES
48
“ I eat a zone or man enough to be comfortable during the game “
“ I eat a zone or on man enough to becomfortable duringmy performance ”
“ Del Piero Say Me ……..”
• < 20 g al giorno di CHO o < 5% dell’energia totale giornaliera da CHO utilizzo dei grassi
• L’originale KD era prevista come 4:1 lipidi:non‐lipidi con 80% grassi, 15% proteine e 15% carboidrati.
• Modifiche: rispetto al rapportoe non limite all’apportoenergetico con grassi ad libitum (proteine NO)
Recovery Meal Post Exercise
• 7 subjects ingested CHO‐PRO (80g, 28g, 6g), LCHO (80g, 6g) or HCHO (108g, 6g) 10‐min and 2‐hr after completing glycogen‐depleting cycling exercise.
• Before exercise and 4‐hr into recovery, muscle [glycogen] was determined via 13C‐NMR spectroscopy.
• Results indicated that CHO‐PRO significantly increased muscle [glycogen] relative to LCHO & HCHO.
0
10
20
30
40
50
LCHO HCHO CHO‐PRO
% glycogen restored
Ivy et al., 2002 (J Appl Physiol)
PROTEIN QUALITY
intracellular, [Leu
cine
]
Katsanos CS, Kobayashi H, Sheffield‐Moore M, et al . Am J Physiol. 2006;291:E381–7.Glover EI, Phillips SM, Oates BR, et al.. J Physiol. 2009;586: 6049–61
Sports Med (2014) 44 (Suppl 1):S71–S77
Leucine is a key amino acidin stimulating MPS and itscontent in whey protein isprobably a primary reasonwhy whey protein is soeffective at stimulatingMPS as opposed to isolatedsoy and casein proteins
Proteins containing a high content of leucine that are digestedrapidly are most effectively directed toward MPS;
Ingestion of foods such as milk promote a robust stimulation of MPSand highlight the fact that ‘blends’ of fast and slow proteins are stilleffective in stimulating MPS
P70S6KMRF4MyoD
Myogenin
EAA
Muscle IGF-1
EAA
MUSCOLO
SANGUE
+
Modificata da: Willoughby D.S.: ISSN presentation, 2007
CREATINA
Carboidrati
• NON essential amino acids are not required for SP
• It takes 3 g of EAA to a partial stimulation of PS (Miller et al. 2003).
• 100 g of CHO can increase the SP by 35% ...... but 6 g of EAA increase the SP of 250% (Biolo et al. 1997, Borsheim et al. 2003).
• 20 g of EAA to optimize the SP (Drummond et al. 2008. J Appl Physiol. 104:1452‐61)
• 20 g of whey good quality ~ 8‐12 g of EAA (and ~ 2 g of leucine)
ESSENTIAL AMINO ACIDS
1) An acute exercise stimulus, particularly resistance exercise, and protein ingestionboth stimulate muscle protein synthesis (MPS) and are synergistic when protein consumption occurs before or after resistance exercise.
2) For building muscle mass and for maintaining muscle mass through a positive muscle protein balance, an overall daily protein intake in the range of 1.4–2.0 g protein/kg body weight/day (g/kg/d) is sufficient for most exercising individuals, a value that falls in line within the Acceptable Macronutrient Distribution Rangepublished by the Institute of Medicine for protein.
3) There is novel evidence that suggests higher protein intakes (>3.0 g/kg/d) may have positive effects on body composition in resistance‐trained individuals (i.e., promote loss of fat mass).
2010
Supplementi per i quali la letteratura scientifica ha dimostrato una certa efficacia e sicurezza di utilizzo.
Supplementi i cui studi iniziali hanno confermato un possibile uso in campo sportivo, ma richiedono maggiori indagini per stabilirne l’efficacia sull’allenamento e/o il recupero.
Supplementi per i quali esiste solo un interesse teorico e la mancanza di una ricerca applicata non consente ancora di approcciarne un utilizzo in campo sportivo.
Supplementi senza alcun razionale scientifico, poiché le ricerche hanno chiaramente dimostrato la loro inefficacia nel migliorare la prestazione e/o il recupero.
Potential Ergogenic Benefits
• Increased single and repetitive sprint performance
• Increased muscle mass & strength adaptations during training
• Enhanced glycogen synthesis • Increased anaerobic threshold • Possible enhancement of aerobic
capacity via greater shuttling of ATP from mitochondria
• Increased work capacity• Enhanced recovery• Greater training tolerance