folding molecular. camila cruz

FOLDING

• Many chromosomal parsare lost or gained togeheracross various cancertypes.

• This chromosomalaberrations can develop a differents cancer typessuch as: Kidney, skeletonand liver cancer.

Patterns of chromosomes Abnormality:

The key to cáncer?

• The CPEB (Cytoplasmicpolyadenylation element binding protein) is a RNA-binding protein that promotes the elongation of the polyadenine tail of messenger RNA.CPEB most commonly activates the target RNA for translation, but can also act as a repressor.

Making memories last:

Prion-like protein plays

key role in storing long-

term memories.

Making memories last: Prion-like protein plays key role in storing long-term memories.

Science Daily (January. 23, 2012).



• The prion domain of CPEB causes self-perpetuation in neurons and this is the

mechanism that maintains long-term memory in neurons.



• The Orb2 and the CPEB has the same function apparently , shows the organisms with relatively

simple nervous systems offer a realistic platform to understand how and where memories are formed

and stored in defined neural circuits.



• This kind of study may help to the doctors and the scientists to understand all pathologic process in the neurodegerative disease, and also give them an idea to treatment. In the new the scientist tries to make emphasis in some common pathology caused by proteins like: Alzheimer Huntington Parkinson and Creutzfeldt-Jakob this show us that oligomer-linked diseases are relatively common.

Patterns of chromosome abnormality: The key to cancer?

Science daily (Jan. 27, 2012)



• Cancer may be defined as a progressive series of genetic events that occur in a single clone of cells because of alterations in a limited number of specific genes: the oncogenes and tumor suppressor genes.



• The association of consistent chromosome aberrations with particular types of cancer has led to the identification of some of these genes and the elucidation of their mechanisms of action.

• The study and the different theories about the memory development are very important in the medicine, because the existence of oligomers and proteins for example the CPEB allows to find new answer and new treatment in the neurological disease like the Alzheimer or dementia.

• The existence of this kind of proteins like CPEB in the neurons can help to the medical staff to understand strange pathologies as well as prion disease, because this kind of disease involve spread in the brain of toxic oligomers of various protein, so only with the interruption of spread of this protein could be the solution for the creutzfel-jakob disease.

• The different kind of embryonic cancer types can be develop owing to a: the abnormality in the synthesis of chromosomes and the chromosomes aberration. From the information that gives us a karyogram we can prevent the development and expansion of the cancer, and we can to know since the intrauterine life the high risk of suffer it.

BIBILIOGRAFIA

• Patterns of chromosomes Abnormality: The key to cancer? (Online) http://www.sciencedaily.com/releases/2012/01/120123115527.htm (January. 23, 2012)

• Making memories last: Prion-like protein plays key role in storing long-term memories (online) http://www.sciencedaily.com/releases/2012/01/120127162409.htm (January. 27, 2012)

http://www.sciencedaily.com/releases/2012/01/120123115527.htm




folding molecular. camila cruz

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