S o u t h S u d a n P e a c e c i r c l e

FO

CU

S

2013

40 years of civil war... Will curing blindness bring peace?

university of utah health care

John A. Moran Eye Center

Moran advisory council2

013

Wayne ImbrescIa John A. Moran Eye Center

claudIa s luttrell Salt Lake City, Utah

robert e marc, Phd John A. Moran Eye Center

John a moran Palm Beach, Florida

randall J olson, md John A. Moran Eye Center

chase n Peterson, md Park City, Utah

lynn Ward John A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye Center

steve Wynn Las Vegas, NevadaLas Vegas, NevadaLas Vegas, NevadaLas Vegas, NevadaLas Vegas, Nevada

norm a ZabrIskIe, md John A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye Center

robert F bennett Falls Church, Virginia

John bloomberg La Jolla, California

reed brInton Salt Lake City, Utah

alan s crandall, md John A. Moran Eye Center

Ian cummIng Jackson Hole, Wyoming

steve deZII Las Vegas, Nevada

sPencer F eccles Salt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, UtahSalt Lake City, Utah

gregory s hageman, Phd John A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye CenterJohn A. Moran Eye Center

alan hIrschFIeld Jackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, WyomingJackson, Wyoming

Fo

cu

s 2

013

1

2 Message from the Chair The Words of a Mother, the Miracles of Vision and Peace Today

4 South Sudan Seeing Your Enemy in a New Light

8 Night for Sight Dedicated Volunteers, Friends, and Generous Donors

10 Highlights

13 Ophthalmologists

18 Val A. and Edith D. Green Foundation Three Generations of Giving

19 Every Little Bit of Kindness Comes Back

22 Charitable Saturday Surgery Day

24 Andy’s Unexpected Pit Stop

27 Research Team

30 Our Mission is Remission Diagnosis and Treatment of Uveitis

32 Moran Researchers Upend Prevailing Theories about Rare Childhood Disease

34 Shedding New Light on Retinopathy of Prematurity

36 Residents and Fellows 2013-2014

38 Moran’s New Resident Continuity Clinic

40 A Clear Vision of Service

41 Community Clinics

42 David Kelby Johnson Hope Fund

44 The Expanding, Enduring Legacy of Sam Skaggs

46 Second Suns Moran’s Drs. Geoffrey Tabin

and Sanduk Ruit

48 Donors 2012

54 Appointments, Honors, and Awards 2012-2013

56 Industry Leadership and Service

62 Clinical Trials

64 Technology Commercialization and Intellectual Property/Patents 2012-2013

66 Grand Rounds

68 Published Research

72 Research Grants and Contracts 2012-2013

79 National and International Presentations

Official Publication of the John A. Moran Eye Center University of Utah Health Care, Salt Lake City, Utah 84132

John A. Moran Eye Center 65 Mario Capecchi Drive Salt Lake City, UT 84132 801-581-2352

EDIToR Steve Brown, Communications Manager

ExTERNAL RELATIoNS TEAM/CoNTRIBUToRS Linda Bult, Editor, WriterTawnja Carballo, Development SpecialistB.J. Fullmer, Administrative AssistantKirsten Mallik, Director of DevelopmentEsther Pomeroy, Communications SpecialistHeidi Reid, Development OfficerLynn Ward, Executive Director

INTERNATIoNAL DIVISIoN oF oPHTHALMoLoGy AND LoCAL oUTREACH Julie Crandall, Project Coordinator Tara Kisow, Program Coordinator Michael Yei, Manager

CoNSULTANTS Virginia Rainey, Editor, Writer

GRAPHIC DESIGN Spatafore & Associates

PHoToGRAPHy Steve BrownLaurel DokosJames Gilman, CRA, FOPSBryan W. Jones, PhDAce KvaleSteve LeitchBrandee MichaelsonTimmy O’NeillPatrick ReddishMichael Schoenfeld

PRINTING Printers Inc. Salt Lake City, Utah

A special thanks to the many hard working Moran Eye Center employees, management, health care workers, physicians, patients, and researchers who generously contributed their time and talent to make this publication possible. Special thanks also to Kay Spatafore and Lori Garfield, Designers.

For more information about the Moran Eye Center, visit our website: www.moraneyecenter.org. Follow us on Facebook at Moran Eye Center and on Twitter @MoranEyeCenter. Requests for additional copies of this publication may be sent to the following: Communications Manager, Moran Eye Center, 65 Mario Capecchi Drive, Salt Lake City, Utah 84132.

©2013 John A. Moran Eye Center. All rights reserved. The Moran Eye Center does not assume responsibility for any representation therein, nor the quality or deliverability of the product themselves. Reproductions of articles or photographs, in whole or in part, contained herein are prohibited without express written consent of the publisher, unless otherwise stated.

J o H N A . M o R A N E y E C E N T E R

ContentsFOCUS 2013

patient care1

research

outreach

education

Fo

cu

s 2

013

2

Fo

cu

s 2

013

3

“When Dr. Olson told me about his dream to carry out research that might someday restore vision to the

blind, it brought to my mind stories my mother read to me as a child,” John says. “As a little boy, I was

particularly touched by the stories of the blind beggar, the power of faith, the miraculous restoration of

sight, and being kind to our neighbors as well as toward strangers. One of the reasons this building exists is

because my mother planted within me a belief in miracles. Even today, these many decades later, my vision

of life’s possibilities is influenced by my mother’s love.”

I’ve told John’s story many times, but it feels especially fitting for this publication as we spotlight our outreach

programs. I watch in awe as this simple yet profound story plays out through our local and international

charitable programs every day. While I’m confident the devoted researchers at the Moran Eye Center will

play a big role in discovering treatments and cures for blinding eye diseases in the near future, until that time

comes, we will bring sight to as many individuals with curable blindness as we can—not sometime in the

future, but today. Fulfilling the vision that John Moran’s mother instilled in him as a young boy cannot wait!

We receive word of these modern miracles of sight restoration through regular updates from our doctors in

the field. Here’s an example from our most recent mission to South Sudan.

Message from the Chair

Did you know that by the age of eight, the average child has heard between 13 and 48 million words from his or her mother? Our mother’s words act as a compass as we navigate through life. When we’re young, we may reject them, but soon we lean on them, recite them, and eventually live by them. John Moran, our chief benefactor and namesake, can point to words his mother said that changed not only his life but the lives of countless individuals throughout the world.

mir

ac

lesThe Words of a mother, the miracles

of Vision and Peace Today of Vision and Peace Today

Randall J Olson, MD, Professor and Chair Division of Ophthalmology, University of Utah; CEO Moran Eye Center

Young South Sudan patient will soon see again

sighT

Journal entries from the lost Boys clinic, south sudan:

Our first story in this issue is about the Moran Eye Center’s five-year commitment to help cure treatable blindness in

the world’s newest, and one of the most violent countries, South Sudan. It is also about peace. It’s about a second

miracle where the leaders of three warring tribes came together in a peace observance with their fellow South

Sudanese citizens—regardless of tribal affiliation—who had received the gift of sight. We have now watched this

extraordinary event take place and, in this issue, you can read about its extraordinary effects on the lives of individuals

and the improved situation between the various tribes.

This year, we celebrate the twentieth anniversary of the John A. Moran Eye Center. In the appendix of this annual

report, we highlight our growth and accomplishments for 2012; but perhaps one of our most extraordinary

achievements can be found in the evidence from South Sudan—that we are successfully navigating the compass

points taught to John Moran by his mother.

Peace

Randall J Olson, MD Professor and Chair of OphthalmologyCEO, John A. Moran Eye CenterUniversity of Utah

Day Three “The team completed 34 cataract surgeries. Patients from all three opposing tribes (the Nuer, Dinka, and Murle) were brought together under the dire circumstances of blindness.”

Day Four “The team completed 34 more cataract surgeries. While some spent endless hours in the extremely hot operating room, others offered post-operative care for patients in the blazing sun.”

Day Six “The peace initiative was a huge success. Formerly blind patients, their families, and leaders from the warring tribes gathered together in peace to discuss how the sight-restoring surgeries will change their lives. The evening concluded with a group hug between the three tribes, resulting in tears from all.”

—Michael Yei, Moran International Division Manager

South Sudan Peace Circle 2012

Lloyd Williams, MD, John Dau, Alan Crandall, MD, Geoffrey Tabin, MD—South Sudan 2011

John Dau and Randall J Olson, MD

Fo

cu

s 2

013

5

Seeing Your Enemy in a

New Light

Seeing Your Enemy in a

What can one man and ophthalmologists from the Moran Eye Center do to bring peace to South Sudan that United Nations peacekeepers, diplomacy, and millions of dollars in international aid have struggled to do? The answer lies in a simple ten-minute sight-restoring surgical operation and a commitment to peace.

Hope and Heartbreak South Sudan is the newest country in the world and one of the poorest. �ere are literally no ophthalmologists in this country of ten million, resulting in nearly one million of its citizens living with blinding eye diseases. Tragically, the vast majority of these individuals could have their sight restored with a common eye surgery. Everyday life is a struggle to survive in South Sudan, but becoming blind is an early death sentence—without the ability to see, a blind person cannot care for him or herself and is a physical and �nancial burden to family, village, and nation.

In 2011, South Sudan gained independence, but at a devastating price: between 1983 and 2005, 2.5 million Sudanese were killed in the civil war, leaving behind more than 20,000 displaced or orphaned children. �ousands of those children, known as the “Lost Boys of Sudan,” �ed the war on foot over 1,000 miles to Ethiopia. John Dau is one of three leaders of 3,800 Lost Boys who relocated to the United States. His horri�c experiences compelled him to establish the John Dau Foundation and open the Duk Lost Boys Clinic in his home village of Duk Payuel.

Dr. Alan Crandall and John Dau—Sowing Early Seeds of Peace In 2006, Moran’s Dr. Alan Crandall, Co-director of the Division of International Ophthal-mology and Professor and Senior Vice Chair of Ophthalmology at the University of Utah, met John Dau. Dr. Crandall had been performing sight-restoring missions in other parts of Africa for more than a decade. Moved by the younger man’s remarkable vision and tenacity, Dr. Crandall pledged to bring eye care to the Duk Lost Boys Clinic.

Sou

th S

udan

South Sudanese man needlessly blind from untreated cataract

A blind patient in South Sudan has his eyes examined before surgery

Dr. Tabin, John Dau and Dr. Crandall, 2011 South Sudan mission

In December 2011, a Moran surgical team was �nally able to enter the country, but only under the protection of armed guards. "�is was actually our third attempt to go into this region. Twice we were turned back because of violence, but we persisted,” says Dr. Crandall.

�e �rst eye camp was a challenge unlike anything the Moran team had ever experienced. In high humidity with tempera-tures exceeding 105 degrees, the cinder block operating room allowed insects, bats, snakes, and lizards to �y and slither through open entryways and windows. �e electricity would cut o� without warning. Patients walked for days through a war zone to get to the clinic. �ere was disease and malnutri-tion at every turn. Despite these extreme conditions, the eye camp was a success. Two hundred forty-one people received the gi� of sight through cataract and trachoma operations. Skeptical patients, who arrived at the clinic led with a stick by their children, departed under their own power.

�e Moran team was also reminded of the violence all around them. �ey heard daily gun�re, and during their stay, 40 people in a nearby village were killed and 16 children were taken into slavery. A�er the team le�, a wave of intertribal vio-lence surfaced in a village just 150 miles southeast of the clinic that took the lives of 3,000 individuals. Tragically, one of the patients, Lonnie, who had his sight restored at the clinic, was killed shortly a�er leaving.

A Commitment to Peace During the 2011 mission, Dr. Crandall made a commitment to Dau that he would carry out four more medical missions to South Sudan. In addition, Dau suggested that as a way to miti-

gate South Sudan’s continuing warfare, the Moran team could tie future medical missions to peace; Dr. Crandall agreed. �e Moran team would not return to perform eye surgeries unless the warring tribes pledged to assemble together in peace for a shared eye camp. With this mandate, a�er the clinic ended, those who had been given the gi� of sight and their families and friends returned home and spread the wonderful news of the eye camp and the conditions for the next one. Local and state agencies also spread the word about the clinic and the peace agreement throughout the region, and many of the tribal leaders agreed to the terms.

Sight is a Precious Thing Jump ahead one year to December 11, 2012. A ��een-member medical team from Moran arrived for a second eye care mis-sion at the Lost Boy’s Clinic with hope that their plan for a peace summit would become a reality. �e team included ophthalmologists Roger Furlong, Alan Crandall, and Charles Weber. �e team packed 2,000 pounds of their own equipment over 8,000 miles to be “greeted by a lot of smiling faces,” said Dr. Weber.

Wary of other warring tribes, once again hundreds of blind, hungry, and sick Sudanese walked miles to the Lost Boy’s Clinic, risking their safety for the promise of sight. Over 600 were screened. At the end of the week, 227 individuals, includ-ing Murle, Nuer, and Dinka tribal leaders, gained sight—some for the �rst time—others a�er years and even decades without vision.

New

Hop

e

Fo

cu

s 2

013

6

Pea

ce

Miracles

�e experience was profound. As the surgical bandages were removed during the week, warring tribal members saw each other—for the �rst time—as comrades, relishing the gi� of sight—not as mortal enemies. “�is is a very stoic culture,” said Dr. Weber. “�ey usually don’t show any kind of out-ward emotion. But to see patients break out in song and hug is pretty incredible.” Moran International Division Manager Michael Yei reported at the time: “I just watched two elderly women, post-op, wander through the camp looking up at everything and occasionally stopping to hug each other. Sight is a precious thing.”

Drunk from Love Near the end of the eye camp, the stage was set for a special planned peace circle. Imagine if you will, the following scene as depicted by several who experienced this event: Patients from the warring tribes and their leaders, friends, and families are sitting in a circle under the quiet beauty of the African

South Sudan tribal leaders and John Dau (right foreground) discuss improving relations during peace circle ceremony, 2012, as Moran’s medical team looks on.

Pre-op patients

skies—many patients are seeing the sunset or the faces of their children or grandchildren for the �rst time. As they look across the circle, they see the faces of patients from other tribes in a whole new light.

�e sudden gi� of sight produces such overwhelming joy in the circle that thoughts of war, hatred, and anger dissolve. Former enemies become kindred souls. �ey smile at each other and tears �ow as they embrace—now citizens of one nation. Dau described the experience this way, “Patients looked absolutely like they were drunk, and actually they were drunk—from love. You can see clearly that there is love among the people of Jonglei State!”

When all have assembled, Dau stands up to speak. He is all of six-feet, eight-inches tall with a captivating voice and an eloquent manner. A report from the �eld says that all eyes are on him, as he says to the group, “We want to disarm your hearts,” earning him a sincere round of applause.

�e Moran team needed key words such as “Don’t move” translated into three tribal languages

“As the surgical bandages were removed during the week, warring tribal members saw each other—for the �rst time—as comrades, relishing the gift of sight—not as mortal enemies.”

Fo

cu

s 2

013

7

Post-op patients participating in the peace circle

Dau continues to inspire, and his message is truly felt by members of all tribes. He then opens up the discussion. In a statement that re�ects the feelings of all the patients, a woman declares, “Peace is possible when you can see the other party. Now that we can see each other, let us unite and become mes-sengers for peace.”

Peace is Possible When You Can See the Other Party �ere have been con�icts in other parts of South Sudan since the 2012 camp. Yet, a�er the latest eye mission and the peace circle, a recent report said there has been peace in the region for the �rst time in many years. A John Dau Foundation trip report on the 2012 eye camp included remarks from patients who participated in the peace circle:

Police First Lieutenant Lam Kong from Uror County who was partially blind by cataract said, “�e �rst time I have heard of someone who have restored eye sights for free is in the Bible…

and the second time is today, and they are these doctors. Lou Nuer and Jiang (tribes) are now one people, and you will never hear of any con�ict again.”

Elijah Bol Kuot from Twic East County said, “For those whose eye sight was restored, will you not communicate this miracle that has happened to your youth to stop raiding other villages? Peace is possible when you can see the other party. Now that we can see each other, let us unite and become the messengers for peace in Jonglei State. Let’s stop our thieves from causing trouble to the neighbor country.”

Nyaboth Tutdel from Ayod County said, “Americans who were brought here by John Dau are either sent by God or they are the real God’s people. How can they leave their families behind and come to help open our eyes?”

Patients wait to have their eyes screened

“Patients looked absolutely like they were drunk—actually they were drunk, from love. You can see clearly that there is love among the people of Jonglei State!” —John Dau

2014

“DISARM THEIR HEARTS” A Vision of SustainabilityThe Sudanese people have experienced only 15 years of relative peace in the past 60 years. Like all peace initiatives, this one will take time to measure in terms of long-term success. After hearing the success of the first sight-restoring peace initiative, leaders from other states now want Moran ophthalmologists to bring eye care missions and the peace ceremony and experience to their residents.

A team from the Moran Eye Center is preparing to carry out a third mission to South Sudan in January 2014. The goal is to bring sight to more than 300 members of multiple tribes from the extremely isolated and neglected region that has been called the “Conflict Triangle.”

While these first missions are important, with almost one million citizens of South Sudan experiencing blindness year after year, at this rate it would take more than 3,000 years just to restore their sight. Fortunately, it won’t take that long. A key component of our international outreach vision and the vision of the John Dau Foundation is one of self-sustainability. With continued support from many wonderful people, one day these clinics will be staffed and run by the people of South Sudan—and the good news is, this program has already begun.

Two assistants from the Lost Boy’s Clinic recently went to Nairobi, Kenya for ophthalmic training and will return to Sudan as certified technicians. It won’t be long before they will be able to treat trachoma by themselves and to train other South Sudanese to do so, long after the Moran team is gone. It is our vision that in the not too distant future, eye care will become self-sustainable in South Sudan, and vision clinics that include peace ceremonies will become a yearly tradition that spreads across all 14 states in that country, so that everyone will have a chance to “disarm their hearts.”

Fo

cu

s 2

013

8

Fo

cu

s 2

013

9

Night for Sight

2013

Thanks to a stellar committee and more than 530 supportive guests,

sponsors, and donors, The John A. Moran Eye Center’s annual Night for Sight gala was

a rousing success. Held on June 22, 2013, at Salt Lake’s Grand America Hotel, Moran’s

premiere fundraiser brought in much-needed funds to support local and international

outreach programs that are an integral part of our mission to treat and cure preventable

blindness and vision loss at home and around the world.

Amid panels of stunning, large-format photography

that documented Moran’s charity care locally and

abroad, guests gathered for an elegant reception and dinner along with live and

silent auctions. Bidding opportunities were as varied as a chance to drive BMW race

cars on a private track to working alongside Moran medical teams at surgical eye

camps deep in the Himalayas. Guests bid on many one-of-a-kind items, including

“The World’s Best Dinner Party” with chef Mikel Trapp and a private concert with

Emmy-winning composer Kurt Bestor. Another opportunity celebrated “The Kid

Inside” with a chance for 20 friends to join in a day of grown-up “sandbox” play,

learning and operating a full suite of earth movers from Intermountain Bobcat, and

savoring a privately catered south-of-the-border style dinner afterwards.

Dedicated volunteers, friends, and generous donors create a special evening to remember

Moran doctors in South Sudan

Short films illustrating Moran’s outreach efforts rounded out the evening, as did an inspiring speech by Moran CEO and Department Chair Dr. Randall Olson. Attendees learned about the unprecedented five-year peace and sight-restoration mission that Moran is carrying out in South Sudan in an alliance with John Dau and the Duk Lost Boys Clinic. Moran surgeon Dr. Geoffrey Tabin, the subject of the highly anticipated best seller Second Suns, also read touching passages from the book.

Everyone who attends or volunteers at Night for Sight is a critical part of our effort to end unnecessary blindness. Donors of time or money support a proud tradition that spans three decades of providing medical care for the underserved, locally and around the world. Just last year, Moran Eye Center ophthalmologists donated their time and talents carrying out sight-restoring missions in fourteen countries on five continents. Moran doctors are also training doctors from Ethiopia, Tanzania, Ghana, Nepal, China, Trinidad and Tobago, India, Bhutan, El Salvador, South Sudan, Indonesia, and Kenya to perform sight-restoring surgeries in their own countries.

Special thanks to our Honorary Chairs John and Marva Warnock, Event Chair Carol Firmage, and the volunteer committee who worked tirelessly to create such a special evening. Thanks also to Drs. Geoff Tabin and Alan Crandall, co-directors of Moran’s International Division. We are also grateful to the many community and business leaders throughout the Salt Lake Valley, Park City, and the entire Wasatch Front who participated in the event. And finally, a sincere thanks to the medical professionals from Moran and all of our industry partners who volunteer time and resources to do outreach work in Utah and around the world.

See the video shorts and learn more about Night for Sight at www.moraneyecenter.org. If you are interested in volunteering, attending, or receiving information about sponsoring the next Night for Sight, please contact the Moran Eye Center Development Office at 801-585-9700 or email heidi.reid@hsc.utah.edu.

THANK YOU TO OUR NIGHT FOR SIGHT SPONSORS

Presenting SponsorsBMW of Murray

BMW of Pleasant Grove

MINI of Murray

Elizabeth A. Johnson, in memory of David Kelby Johnson

O.C. Tanner

John and Marva Warnock

Platinum SponsorsBamberger-Allen Health & Education Foundation

Grand America Hotel

Claudia Skaggs Luttrell

Reagan Outdoor Advertising

Visionary SponsorsJohn and Toni Bloomberg

George S. and Dolores Doré Eccles Foundation

FFKR Architects

SD Stewart Foundation

Zions Bank

Table SponsorsBennion Jewelers

EnergySolutions

Fred and Christine Fairclough

FreeportWest Industrial Properties

Justin Grant Photography

Legislative Insight Consulting LLC

Lipman Winston

Mayor Ben McAdams

Molina Healthcare

Julie Nester Gallery

HONORARY CHAIRS John Warnock, Scott Murray, Marva Warnock; Event Chair Carol Firmage

Mark Miller, Dr. Randall J Olson Dr. Geoff Tabin

Fo

cu

s 2

013

10

Fo

cu

s 2

013

11

m o r a n e y e c e n t e r H I G H L I G H T S

RANDALL J OLSON, MD, Professor and Chair of Ophthalmology and Visual Sciences, CEO, John A. Moran Eye Center, University of Utah School of Medicine

Dr. Randall J Olson completed his undergraduate training and medical schooling at the University of Utah (BA ’70, MD ’73); his residency at UCLA in 1977 in ophthalmology; and fellowships in cornea at the University of Florida in Gainesville and at the Louisiana State University Eye Center in New Orleans, where he joined the faculty in 1977 as Director of Corneal Services. Dr. Olson started as a one-person Division Chief in June, 1979, at the University of Utah and has been Chief of Ophthalmology ever since. During this time, he has directed the building of two eye centers and managed faculty that has expanded from one to over fifty members today. And now, more than half of the current 210,000-square-foot Moran Eye Center, built in 2006, is dedicated to research.

Rand

all J

Ols

on, M

DDr. Olson Receives Four New HonorsThe Moran Eye Center faculty, staff, as well as our patients, supporters, and friends feel it is a privilege to work with our remarkable chair and CEO, professor and surgeon, Dr. Randall J Olson. It is always special when we hear that Dr. Olson has received an honor from his colleagues, universities, or other institutions. Adding to his many awards, we’re pleased to announce that Dr. Olson recently received FOUR major accolades:

The Fourth Annual Distinguished Ophthalmic Educator Award, University of Iowa Carver College of Medicine, Iowa City, Iowa, May 17, 2013. Dr. Olson was also guest faculty and the keynote speaker at this event. This award was given to Dr. Olson for his many accomplishments and years of contributions to ophthalmology, education, and patient care.

The Dr. Clark Lowe Rich Distinguished Surgeon Award. Educator, University of Utah, Salt Lake City, Utah, May 23, 2013. This award recognizes one outstanding surgeon each year at the University of Utah who has demonstrated exceptional skill and dedication in the field of surgery, including teaching, advising, and mentoring medical students, interns, residents, or fellows. The recipient is a role model in the tradition established by Dr. Rich during his lifetime of service in surgery and patient care.

The 34th Annual Tullos O. Coston Lectureship at the Dean McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma, June 8, 2013.This lectureship was established in honor of the enormous contributions of founding ophthalmic surgeon Dr. Tullos O. Coston. Held at the Annual Resident and Alumni Meeting, distinguished ophthalmologists are invited to share their research, interest, and expertise.

The 44th Annual Jules Stein Pettit Lectureship Award, Jules Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, California, June 14, 2013. The Pettit Lecture is awarded to clinical researchers with outstanding research throughout their careers, who are invited back to the institute where they trained, to share their findings with the residents, fellows, and faculty of the Jules Stein Eye Institute and the UCLA School of Medicine.

Four Major Awards

Balamurali K Ambati, MD, PhD, MBA is Appointed the Official Utah Utes Team OphthalmologistDr. Bala Ambati, Professor, Department of Ophthalmology and Visual Sciences and Adjunct Associate Professor of Neurobiology and Anatomy at the University of Utah Health Center was appointed team ophthalmologist for the University of Utah Utes in August 2012. “I’ve always been interested in eye trauma, sports medicine, and the Utes,” says Dr. Ambati. “I take care of coaches and staff as well as the athletes. I’ll treat any injuries to the front of the eye such as scratches, rup-tured globes, chemical burns—and perform routine eye exams and treat any eye diseases that they may have.”

Dr. Ambati also provides eye injury prevention, eye trauma, and eye health edu-cation for athletes and coaching staff. He cannot stress enough the importance of wearing protective goggles to avoid foreign objects getting into or hitting the eyes. He would like to express his “special thanks” to Trevor Jameson, the Utes’ head athletic trainer.

Dr. Ambati has the distinction of being the world's youngest person to graduate from medical school at age 17. He is experienced in cornea transplants, cata-ract extraction, keratoprosthesis (artificial cornea), LASIK, and other complex procedures of the cornea and anterior segment of the eye. He conducts pioneer-ing work in showing what keeps the cornea clear and is developing novel drug delivery systems for several eye diseases.

Unprecedented—Nick Mamalis, MD, Named Moran’s Second Binkhorst Medal Winner Dr. Nick Mamalis, Professor of Ophthalmology at the University of Utah, has received the American Society of Cataract and Refractive Surgery’s (ASCRS) greatest tribute—the Binkhorst Medal of Honor, an award of global prominence. This award marks an unprecedented honor for Moran Eye Center, as Dr. Randall J Olson was the 2012 recipient. Binkhorst Medal winners are selected for their “significant contributions to the science and practice of ophthalmology.”

Dr. Mamalis’ work, specializing in the study and understanding of toxic anterior segment syndrome, has established him as a leader in the field of ophthalmol-ogy. He was presented with the award at the ASCRS and American Society of Ophthalmic Administrators Symposium and Congress in San Francisco, April, 2013, where Dr. Mamalis delivered the Binkhorst Lecture.

His lecture, “Intraocular Lens Evolution: What a Long, Strange Trip it’s Been,” explores the “history and future of IOL implantation and traces surgical techniques from the beginning to the next technological frontier in providing clear and uncorrected distance, intermediate, and near vision following cataract surgery.”

Dr. Mamalis is a practicing ophthalmic surgeon, Director of the Ophthalmic Pathology Laboratory at the Moran Eye Center, Co-director of the Intermoun-tain Ocular Research Center, Chairman of the ASCRS Task Force, and an editor of the Journal of Cataract & Refractive Surgery.

Bala

mur

ali K

Am

bati,

MD,

PhD

, MBA

Nick

Mam

alis

, MD

Binkhorst Medal

Utah Utes Team Ophthalmologist

Fo

cu

s 2

013

12

Yingbin Fu, PhD, Wins “Challenge to Identify Audacious Goals” Dr. Yingbin Fu, Assistant Professor of Neurobiology & Anatomy, Neuro-sciences, Molecular Biology, and Director of Model Development, Moran Center for Translational Medicine, was one of 10 esteemed winners of the National Eye Institute (NEI) “Challenge to Identify Audacious Goals in Vision Research and Blindness Rehabilitation,” 2013. His winning submission: “Precise Gene Editing In Vivo” aims to permanently correct (by being delivered safely and efficiently into the eye) any disease-associated mutations in a patient through the use of molecules specially designed to target mutated DNA sequences.

“If this goal is achieved, the impact would be enormous in the prevention and cure of human diseases,” Dr. Fu said. “As we enter the era of person-alized medicine, it has become more and more practical to sequence a person’s genome at low cost, which makes it possible for us to catch disease-causing mutations early and before the onset of disease.” Beyond eye disease, this strategy could also be applied to the genetic component of virtually any human disease, whether inherited or resulting from cellular responses to environmental stresses.

“It is an incredible honor for the Moran Eye Center and for Dr. Fu to receive this prestigious and well-deserved award,” said Dr. Randall J Olson, Chair-man and CEO, John A. Moran Eye Center. This work is truly ‘audacious’ in the best sense of the word and revolutionizes this area of science.” In 2012, Dr. Fu was also presented with the “National Eye Institute Travel Award” at the XVth International Retinal Degeneration Symposium, Bad Gögging, Bavaria, Germany.

Ying

bin

Fu, P

hDm o r a n e y e c e n t e r H I G H L I G H T S

Dr. Yingbin Fu with Director of the National Eye Institute, Paul Sieving

Challenge to Identify Audacious

Goals in Vision Research and

Blindness Rehabilitation

Fo

cu

s 2

013

13

CEo of the John A. Moran Eye CenterRandall J olson, MD, is the chair of the Department of ophthalmology and Visual Sciences and ceoof the John A. Moran Eye Center. Dr. Olson is the author of more than 300 professional publications and a worldwide lecturer. He specializes in research dealing with intraocular lens complications, tele-ophthalmology, and corneal transplantation techniques. He was selected as one of the 15 best cataract surgeons in the United States in a peer survey conducted by Ophthalmology Times. Cataract and Refractive Surgery Today named Dr. Olson as one of 50 international opinion leaders. Time constraints limit the Surgery Today named Dr. Olson as one of 50 international opinion leaders. Time constraints limit the Surgery Todaynumber of patients Dr. Olson is able to see, yet he continues to enjoy patient care visits on a regular basis.

specialty• Cataract Services and External Eye Diseases

Doctors in Alphabetical Order

Balamurali K Ambati, MD, PhD, MBA, specializes in cornea transplants,cataract extraction, keratopros-thesis (artificial cornea), LASIK, and other complex procedures of the cornea and anterior segment of the eye. He welcomes patients in these areas as well as general ophthalmic issues. Dr. Ambati also maintains a dynamic research laboratory and has more than forty peer-reviewed publications and two books.

specialties• Cornea• Cataract Services• Vision Correction Surgery

(LASIK, Laser, and Non-laser)• Uveitis

Paul S Bernstein, MD, PhD,specializes in age-related macular degeneration with special em-phasis on the role of nutrition and environment in its treatment and prevention; inherited retinal and macular dystrophies; and surgical treatment of vitreoretinal disor-ders such as diabetic retinopathy and retinal detachments.

specialties• Vitreoretinal Diseases

and Surgery • Retinal Biochemistry• Macular and Retinal

Degeneration

Alan S Crandall, MD, is the Senior Vice chair of the Department of ophthalmology and Visual Sciences, Director of moran’s Glaucoma and cataract Division, and Co-director of Moran’s International Divsion. He focuses on the medical and surgical management of glaucoma and cataracts. Dr. crandall has experience with trabeculoplasty and laser cyclo-photocoagulation. He is involved in numerous clinical research studies at the Moran Eye Center, lectures throughout the world, and was selected by Cataract and Refractive Surgery Today and Refractive Surgery Today and Refractive Surgery Todayas one of 50 international opin-ion leaders.

specialties• Cataract Services• Glaucoma

Susan Chortkoff, MD, focuses on the management and treatment of glaucoma as well as comprehensive ophthalmology. Dr. Chortkoff also has a special interest in the management of dry eye syndrome.

specialties• Comprehensive Ophthalmology• Glaucoma

William Barlow, MD, specializes in comprehensive oph-thalmology with a focus on the surgical management of routine and complex cataracts, anterior segment surgery, and vision cor-rection surgery using laser and intraocular lenses. His current research interest is focused on cataract surgical outcomes.

specialties• Comprehensive Ophthalmology• Cataract Services• Refractive Surgery (LASIK,

Laser, and Non-laser)

Craig J Chaya, MD, specializes in comprehensive ophthalmology with a focus on the medical and surgical manage-ment of cataracts and glaucoma. Dr. chaya also has an interest in international ophthalmology and has worked in Guam, Pohnpei, Ghana, Haiti, Thailand, and Nepal.His research interests include cataract and glaucoma surgery in the developing world.

specialties• Comprehensive Ophthalmology• Cataract Surgery• Glaucoma

2013m o r a n e y e c e n t e r o P H T H A L M o L o G I S T S

Fo

cu

s 2

013

14

David C Dries, MD, provides medical and surgicalcare for a wide range of eye diseases and visual impairments in children as well as evaluation and management of strabismus in both children and adults. He has special interest in amblyopia, esotropia, exotropia, retinopathy of prematurity, retinoblastoma, infant and childhood cataracts, and nasolacrimal duct obstruction.

specialties• Pediatric Ophthalmology• Adult Strabismus

R Michael Duffin, MD, practices comprehensive ophthalmology, specializing in cornea and external eye diseases. He joined the Moran Eye Center after 22 years of private practice experience in California. Dr. Duffin has conducted over 25 humani-tarian eye projects, mostly in Latin America, including cataract surgery and cornea transplants.

specialty• Comprehensive Ophthalmology

Jason Goldsmith, MD, focuses on the medical and surgi-cal management of cataracts andglaucoma. Dr. Goldsmith’s researchinterests include the use of opticalcoherence tomography, an oph-thalmic imaging technology used in screening for angle-closure glaucoma.

specialties• Cataract Services• Glaucoma

Joseph L Hatch, MD, provides expertise and experi-ence in all areas of ophthalmology and has extensive experience in contact lens fitting. In 2008, Dr. Hatch was asked to serve on the Church of Jesus Christ of Latter-day Saints Church Vision Initiative. This program sends eye care profes-sionals to countries throughout the world.

specialty• Comprehensive Ophthalmology

Roger P Harrie, MD,practices comprehensive ophthal-mology and ocular surgery with a subspecialty in ophthalmic ultra-sound. He is the senior instructor in the ocular ultrasound course at the annual american academy of Ophthalmology meeting. Dr. Harrie has made more than 20 humanitarian trips, mostly training doctors in developing countries in diagnostic and therapeutic techniques.

specialty• Comprehensive Ophthalmology

Mary Elizabeth Hartnett, MD,is Director of Pediatric Retina. She specializes in vitreoretinal surgery and treats and manages adult and pediatric retinal cases. She is now building a pediatric retina center and a pediatric and adult retina clinical practice at the Moran Eye center. She performs surgery at both the moran eye center at the University of Utah and the moran Eye Center at Primary Children’s Hospital.

specialty• Pediatric and Adult Retinal

Diseases and Surgery

Alison Crum, MD, specializes in both oculoplastics and orbital surgery—the recon-struction of the bones around the eyes after traumas, cor-recting drooping eyelids, and aesthetic surgeries, such as eyelid lifts. She also practices neuro-ophthalmology, the study of how the eye connects to the brain, and provides medical and surgical treatments for visual disorders. Her interests include treatment of Graves’ disease and treatment of papilledema.

specialties• Neuro-ophthalmology• Oculoplastics &

Facial Plastic Surgery• Ophthalmology

Kathleen B Digre, MD, is a Past President of the North American Neuro-ophthalmology Society. She specializes in neuro-ophthalmology and evaluates and treats complex visual complaints which can be due to optic nerve or brain disease. Her interests include gender differences in neuro-oph-thalmic disorders, pseudotumor cerebri, ischemic optic neuropathy, temporal arteritis, papilledema, episodic vision loss, headaches and eye pain, diplopia and Graves’ Disease. She has worked with the North American Neuro-ophthal-mology Society and the University of Utah Eccles Library to develop a Neuro-ophthalmology Virtual Educational Library (NOVEL) on the internet at http://novel.utah.edu.

specialty• Neuro-ophthalmology

2013m o r a n e y e c e n t e r o P H T H A L M o L o G I S T S

Fo

cu

s 2

013

15

Annie Kuo, MD, specializes in diagnosis and treat-ment of acquired and inherited eye diseases in children, including cataract, glaucoma, amblyopia, and lacrimal disorders. She also provides medical and surgical care to children and adults with strabismus.

specialties• Comprehensive Ophthalmology• Cataract Services• Glaucoma• Adult and Pediatric Strabismus• Pediatric Ophthalmology

Nick Mamalis, MD, is Director of the ophthalmic Pathology Laboratory and evalu-ates all specimens submitted to the laboratory. He focuses his clinical practice on comprehensive ophthalmology including cataract and other anterior ocular surger-ies. Dr. mamalis is the editor of the Journal of Cataract and Refractive Surgery and is a member of the Surgery and is a member of the SurgeryAmerican Association of Oph-thalmic Pathologists. He is also Co-director of the Intermountain ocular research center and is performing research in the area of intra-ocular lenses and postopera-tive inflammation. Dr. Mamalis was selected by Cataract and Refrac-tive Surgery Today as one of the 50 tive Surgery Today as one of the 50 tive Surgery Todayinternational opinion leaders.

specialties• Cataract Services• Ophthalmic Pathology• Comprehensive Ophthalmology

Mark D Mifflin, MD, is Moran’s Education Director and the medical Director of the Utah Lions Eye Bank. He specializes in the medical and surgical treatment of corneal and anterior segment eye diseases. His expertise includes all types of corneal transplantation, cataract surgery, and vision correction using lasers, intraocular lenses, and conductive keratoplasty.

specialties• Cataract Surgery• Vision Correction Surgery

(LASIK, Laser, and Non-laser)• Cornea Transplant Surgery

Majid Moshirfar, MD, FACS,is the Director of moran’s cornea and Refractive Surgery Divisions. He specializes in corneal transplan-tation, keratoprosthesis (artificial cornea), management of corneal disorders, cataract extraction, LASIK, inflammatory eye diseases, and other complex procedures of the cornea and anterior segment of the eye. Dr. moshirfar lectures extensively around the country on a variety of vision correction procedures and has become a community spokesperson on the benefits and risks of vision cor-rection surgery. He has appeared in the last three editions of Best Doctors in America.

specialties• Cornea Transplant• Vision Correction Surgery

(LASIK, PRK, LASEK, Phakic IOL, Intacs, CK)

• Cataract Surgery and Intraocular Implants

• Corneal Inflammatory Eye Diseases

• Artificial Cornea

2013m o r a n e y e c e n t e r o P H T H A L M o L o G I S T S

Robert o Hoffman, MD, is Chief of the Division of Pediatric ophthalmology and eye muscle Disorders. He has special interests in retinopathy of prematurity, ocular genetics, craniofacial disorders, pediatric cataracts, and complicated strabismus.

specialties• Pediatric Ophthalmology• Adult Strabismus

Bradley J Katz, MD, PhD, specializes in neuro-ophthal-mology, cataract, and com-prehensive ophthalmology. He evaluates patients with diseases that affect the optic nerve and diseases of the brain that affect vision and eye movements. Dr. Katz also conducts research in these areas: giant cell arteritis, photophobia and migraine, optic neuritis, and multiple sclerosis.

specialties• Cataract Services• Neuro-ophthalmology

Rachael Jacoby, MD, specializes in medical and surgical diseases of the retina and vitreous. Her primary clinical and surgical interests include retinal detach-ments, diabetic retinopathy, and macular and retinal degeneration.

specialties• Retinal Diseases and Surgery• Macular and Retinal

Degeneration

Fo

cu

s 2

013

16Albert T Vitale, MD, is Director of Moran’s Uveitis Division. He specializes in patients with diseases of the retina and vitreous. He is one of the only oph-thalmologists in the Intermountain West specializing in the diagnosis and treatment of uveitis and other infections and inflammatory diseases of the eye. His research interests include ocular manifesta-tions of systemic diseases, novel therapeutic agents, and new drug delivery systems in the treatment of ocular inflammatory disease, retinal vascular disease, and the pharmacotherapy of age-related macular degeneration. He is one of a few people in the country with dual training in ocular immunol-ogy and inflammatory disease and vitreoretinal surgery. Dr. Vitale is co-author of the definitive text on the subject, with Dr. C. Stephen Foster, entitled, Diagnosis and Treatment of Uveitis.

specialties• Uveitis, Ocular Infections• Retinal Diseases and Surgery

Michael P Teske, MD, is the Director of Vitreoretinal Diseases and Surgery. Dr. Teske specializes in medical and surgical diseases of the retina and vitre-ous. His primary surgical interests include retinal detachment, prolif-erative vitreoretinopathy, diabetic retinopathy, retinopathy of pre-maturity, epiretinal membranes, macular holes, and posterior segment trauma.

specialty• Retinal Disease and Surgery

Judith E A Warner, MD, is Chief of Neuro-ophthalmology, specializing in neuro-ophthal-mology—the study of the eye as it relates to the brain. She evalu-ates complex visual complaints, which can be due to optic nerve or brain disease, and provides treatment for these disorders. Her interests include diplopia, giant cell arteritis, papilledema, optic neuritis, episodic vision loss, idiopathic intracranial hyperten-sion, ischemic optic neuropathy, and unexplained vision loss.

specialty• Neuro-ophthalmology

Geoffrey Tabin, MD, is Co-director of Moran’s International Division. He is a corneal specialist, and in addition to his work in Utah providing corneal, cataract, and refractive care, Dr. Tabin is working to develop eye care delivery in developing countries. Part of his research includes improving cataract and corneal surgery.

specialties• Cataract Services• Vision Correction Surgery

(LASIK, Laser, and Non-laser)

Jean Tabin, MD, provides general vision care and comprehensive ophthal-mology services at the moran Eye Center. Dr. Tabin enjoys working in Moran’s Triage Clinic, treating patients and teaching medical students and residents who are interested in learning more about ophthalmology.

specialty• Comprehensive Ophthalmology

2013m o r a n e y e c e n t e r o P H T H A L M o L o G I S T S

Barbara M Wirostko, MD, specializes in clinical research and drug development for glaucoma pharmaceutical therapies. Her research interest is in sustained delivery of therapeutics for ocular pathologies and approaching glaucoma through non-intraocular pressure mediated approaches.

specialties• Comprehensive Ophthalmology• Glaucoma

Jeff Pettey, MD, is Moran’s Residency Program Director and specializes in comprehensive ophthalmology, complex cataracts, and anterior segment surgery. He coordinates the teaching and training of medi-cal students, residents, interna-tional observers, and fellows. Dr. Pettey also has an interest in local outreach and in international ophthalmology where he works to develop teaching and training collaborations with programs in developing countries.

specialties• Comprehensive Ophthalmology• Cataract Services

Bhupendra C K Patel, MD, FRCS, FRC, is an expert in the management of disorders involving eyelids, periorbital tissues, the lacrimal system, and facial bones, including fractures. His clinical research interests include thyroid disease, optic nerve disorders, orbital and eyelid tumors, blepharospasm, lacrimal surgery, and facial cosmetic surgery.

specialty• Oculoplastic and

Facial Plastic Surgery

Fo

cu

s 2

013

17

Lisa ord, PhD, LCSW, is the Director of the ophthal-mology-based Patient Support Program for people with visual impairment and their families. Services in this program include crisis counseling, information and referral services, support groups, and the Orientation to Vision Loss Program.

specialty• Counseling Related to Vision Loss

Donnell J Creel, PhD, is Director of electrophysiology Service at the John a. moran eye center. the electrophysiology Service provides examinations including visually evoked poten-tials, full-field electroretinograms, auditory brainstem responses, electro-oculograms, multifocal electroretinograms, and multifocal visually evoked potentials. These tests quantitate retinal, optic path-way, visual cortical, and brainstem auditory pathway function.

specialty• Electrophysiology

Derek J Sakata, MD, is the Medical Director for Anes-thesia Services at the John a. Moran Eye Center. Dr. Sakata provides and directs anesthesia care for ophthalmic patients before, during, and after surgery. He also has a background in engi-neering and has been involved in medical device design and subsequent company startups. He continues to be involved in research into new medical device designs and drug delivery.

specialty• General Anesthesiology

2013m o r a n e y e c e n t e r o P H T H A L M o L o G I S T S

Norm A Zabriskie, MD, is the Vice chair and medical Direc-tor of clinical Services and Director of Clinical Operations at the John A. moran eye center. He specializes in the medical and surgical treatment of glaucoma and cataracts. He has a research interest in the genetics of glaucoma.

specialties• Cataract Services• Glaucoma

Marielle young, MD, provides medical and surgical care for children with eye disease as well as adults and children with strabismus. Her clinical expertise includes the evaluation and treatment of amblyopia, strabismus, infantile and developmental cataracts, and nasolacrimal duct obstruction.

specialties• Pediatric Ophthalmology• Adult and Pediatric Strabismus

Alison Crum, MD, specializes in both oculoplastics and orbital surgery—the recon-struction of the bones around the eyes after traumas, correcting drooping eyelids, and aesthetic surgeries, such as eyelid lifts. She also practices neuro-ophthal-mology, the study of how the eye connects to the brain, and provides medical and surgical treatments for visual disorders. Her interests include treatment of Graves’ disease and treatment of papilledema.

specialties• Neuro-ophthalmology• Oculoplastics &

Facial Plastic Surgery• Ophthalmology

Craig J Chaya, MD, specializes in comprehensive ophthalmology with a focus on the medical and surgical manage-ment of cataracts and glaucoma. Dr. chaya also has an interest in international ophthalmology and has worked in Guam, Pohnpei, Ghana, Haiti, Thailand, and Nepal.His research interests include cataract and glaucoma surgery in the developing world.

specialties• Comprehensive Ophthalmology• Cataract Surgery• Glaucoma

Haibo Wang, MD, PhD, Research Assistant Professor of ophthalmology & Visual Sciences.

specialty• Vascular Biology

NEW RESEARCH FACULTyNEW CLINICAL FACULTy

oTHER SPECIALTIES

Fo

cu

s 2

013

18

Fo

cu

s 2

013

19

Every day, the Greens’ contributions impact ophthalmic care at the Moran Eye Center—through the work of inaugural chair-holder Dr. Alan Crandall and at the Val A. and Edith D. Green Foundation Clinical Research Center, where all patients who enroll in Moran’s Center for Translational Medicine (CTM) research are welcomed and examined.

The family’s relationship with Moran stretches back a few decades when age-related macular degeneration (AMD) first struck Mr. Green. Because his vision was so compromised, he could no longer drive and had to take an early retirement from a highly successful career with The Coca Cola Company. “While the doctors at Moran were able to help slow the progression of the disease, they couldn’t prevent it,” says their son, Val Green, of Park City, Utah. “Despite that, the team at Moran built a real desire in my dad to someday help beat AMD. They gave him hope. My mom also had challenges with her vision and ended up having a cornea replaced. Thanks to Drs. Mano Swartz and Alan Crandall and Moran’s Patient Support Program, her vision was fine for years after that.”

Val A. and Edith D. Green Foundation

Three Generations of

When Val A. and Edith D. Green established their Presidential Endowed Chair in Ophthalmology at the University of Utah in 1997, it was with a generosity of spirit that has carried on through the generations.

GIVING

The Greens’ legacy now thrives in their children and grandchildren who are making a difference through the foundation established by Val and Edith’s estate. “My dad loved the Layton area and the Wasatch Front, and he wanted to really help people here,” he notes. “We set the foundation up together with the intention of making it a generational thing, so my entire family is involved, including my wife Elizabeth, my sister Hollie, and her son Brodie. My oldest son, Aaron, is already on the grants board, and Matthew, the youngest, is a photographer who helps document some of our projects. Our causes are fairly eclectic, so there’s a lot of research to do, and it’s important that the whole family knows what’s going on.

“When it comes to Moran,” he says, “we have a long and trusting relationship, so we all know that whatever the needs are, they are worthy. I don’t hesitate to tell people facing vision challenges, ‘this is where you have to go—there is no better place in the country—so put your eyes in their hands.’”

“…the team at Moran built a real desire in my dad to someday help beat AMD. They gave him hope.” —Val Green

Val A. and Edith D. Green

Dr. Crandall has always remembered his father’s philosophy. Whether in his pioneering work in international outreach at Moran or his day-to-day interactions with patients and students, his outlook remains the same: “Every little bit you can do to help can make a big di�erence in the long run. I really believe that. Every little kindness comes back.”

New Presidential Endowed Chair in Ophthalmology Dr. Crandall brings a rich and storied legacy to his newly appointed position as the inaugural holder of the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology. A highly respected surgeon, educator, and humanitarian, he holds the titles of Senior Vice Chair, Director of Glau-coma and Cataract, and Co-director of Moran’s International Division. Among other notable honors, he is a past presi-dent of the American Society of Cataract and Refractive Surgery (2010).

History-making Friendship with Randall J Olson, MDDr. Crandall’s path to the Moran Eye Center began at the University of Utah where he �rst met now-CEO Randall J Olson, MD. As medical students, the two forged a bond, but had no idea what lay ahead in terms of the history they would create over the next few decades. A�er completing medical school, each went his own way for residencies and fellow-ships. Dr. Olson returned to Salt Lake City to become a one-person division of ophthalmology at the U.

COMES BACKDr. Alan S. Crandall honored as the Inaugural Holder of the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology

As the son of one of Utah’s first ophthalmologists, Dr. Alan S. Crandall recalls accompanying his father to the

original St. Mark’s hospital in Salt Lake City where some of his father’s patients paid him on the barter system.

“It wasn’t unusual to receive a chicken instead of cash. My father’s philosophy was that he would treat every-

body exactly the same way. As far as I could tell, he had no prejudice against anything other than stark stupidity.

He was true to his word—he worked hard and loved what he did.”

Every Little Bit of Kindness

Fo

cu

s 2

013

20

back. As we now do worldwide, we have also trained their doctors by bringing them here to Moran. �ey are then able to go back to do the work and to train other doctors.” Because of these and other heroic e�orts, Dr. Crandall points out that the rate of curable blindness has dropped and is now decreasing every year in several third-world countries for the �rst time in history.

“I am honored that the Greens and the University of Utah feel that they can count on me to deliver excellent care, stay on the cutting edge, and continue to spread Moran’s mission of curing blindness in every sphere—locally and around the world,” Dr. Crandall says. “To me, it also means they recognize that I’m a hard worker, and I’m making a di�erence.”

Among many other acts of giving, Dr. Crandall uno�cially initiated Moran’s International Outreach Program. It all began in the late 1970s, a few years a�er Alex Haley’s best selling book, Roots came out. “One of my patients, Gladys Richardson, read it and wanted to �nd out more about her family’s history in Africa,” he says. “She went to Ghana, and when she came back, she talked to me about the dire need for schools and treatments to help reverse the epidemic of blindness caused by cataracts. So I said, what the heck, let’s go over there and see what we can do.

“We made contact with �e Komfo Anokye Teaching Hospital (KATH) in Kumasi, in central Ghana. We started slowly, with just ten to ��een cataract surgeries. At the time, that was what they were able to do in a two-or three-day period. Every year since, we’ve gone

“ALL IT TOOK WAS A CALL FROM RANDY ASKING ME TO JOIN HIM BACK HERE, AND THAT WAS IT.”

—Dr. Alan S. Crandall

“I still remember our first Christmas party. Our division consisted of six people, including three doctors. I brought my boom box in, and we listened to Willie Nelson’s Christmas album. It was great.”

—Dr. Alan S. Crandall

Meanwhile, Dr. Crandall joined the faculty at the Scheie Institute, University of Pennsylvania. He says he enjoyed the Ivy League, but Salt Lake City and its mountain-ringed landscape still called to him. “All it took was a call from Randy asking me to join him back here, and that was it,” recalls Dr. Crandall. I still remember our �rst Christmas party. Our division consisted of six people, including three doctors. I brought my boom box in, and we listened to Willie Nelson’s Christmas album. It was great.” Dr. Crandall says he also felt more at home in Utah sporting his growing collection of bolo ties, which he started wearing in Pennsylvania once he �gured out that he was “not the bow-tie type.”

Eventually, the division became a department. “Our goal was to deliver �rst-rate care and then to expand to become an international center for research. So, we grew with a lot of hard work and a bit of luck. �e fact that John A. Moran also wanted to give back and attach his name to our cause changed everything.” Today Moran has become a global leader in ophthalmology.

Dr. Alan S. Crandall

Fo

cu

s 2

013

21

“Every little bit you can do to help can make a big difference in the long run. I really believe that.”

—Dr. Alan Crandall

Dear Friends and Colleagues:

I have been dying to make this announcement for quite a while, but had to wait until it was official. One of the highest honors that can be awarded a faculty member is to be appointed as a presidential endowed professor, which is the highest of the Endowed Chairs at the University of Utah. Well, it is my distinct honor and pleasure to announce that Alan Crandall, after years of amazing service in every aspect of his career, is now officially the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology! Please join with me in celebrating this distinct honor and thanking this remarkable individual for all he has done for the John A. Moran Eye Center!

Alan, you are the best!!

Sincerely, Randall Olson, MD CEO, JMEC

Dr. Olson sent this email to all Moran employees. It shows the great friendship and admiration he has for Dr. Crandall:

Dr. Crandall in surgery

Fo

cu

s 2

013

23

Debilitating vision problems know no borders. they affect every population and ripple through economies both international and local. that’s why Moran’s outreach Programs aim to reach around the world as well as down the street. Close to home in Salt Lake City, Moran surgeons, medical technicians, and staff donate their services to provide surgery to people in need at Moran’s own surgical facilities one special day each year.

Charitable Saturday Surgery Day at the Moran Eye Center, originally conceived in 2007 by two

fourth-year medical students, is now an established community service with a monumental effort

behind it. one Saturday each year, after months of planning and preparation, Moran staffs up with

40 volunteers, including secretaries, scrub techs, anesthesiologists, technicians, residents, fellows,

nurses, surgeons, and our guest relations specialist to welcome 12 patients, many of whom have

been screened and diagnosed through Moran’s monthly outreach work at the fourth Street and

Maliheh Clinics in Salt Lake City and the People’s Clinic in Park City.

Charitable Saturday Surgery Day

Moran’s Cynthia Johnston, pre-and post-op nurse, readies Leitha Harvey for surgery

Cha

ritab

le

“Mrs. Harvey is a prototype of

many of the patients I see,” says

Moran’s Bradley J. Katz, MD, PhD,

who specializes in cataract surgery

and neuro-ophthalmology and is

one of the surgeons who donates

his services on Surgery Day and

throughout the year at local clinics.

“She is 64, doesn’t yet qualify for

Medicare or Medicaid. She works,

but doesn’t make enough for health

insurance. Even if she did, cataracts

are an elective surgery not always

covered by insurance.”

Not surprisingly, the need for help is

greater than the capacity, so Moran

has scheduled a second surgery day

for October 2013.

Because Moran is the only major aca-

demic ophthalmology center for the

Intermountain West, working at Fourth

Street Clinic for the homeless provides

a unique educational opportunity for

medical students, residents, and

fellows to see pathology that they

would not necessarily see. They pro-

vide volunteer services one Tuesday

evening per month for as many as 25

patients needing eye care.

“While it sounds exotic to travel to

Nepal,” says Albert T. Vitale, MD, who

specializes in retinal diseases and

uveitis and is the Medical Director for

the Moran Eye Clinic at the Fourth

Street Clinic, “plenty of people right

down the street need eye care. Our

work serves an unmet need for the

uninsured and marginalized. It also

gives residents an opportunity to

perform surgeries and expands the

Moran Eye Center’s mission of service

at home.”

“I started crying,” says Leitha Harvey,

about her reaction to having cataract

surgery. “My gosh…everything is so

bright. I’m thrilled; I’m energized; I

have a new lease on life—I’m just so

grateful they gave me back my vision.”

sur

gery

Day

“My gosh…everything is so bright. I’m thrilled; I’m energized; I have a new lease on life—I’m just so grateful they gave me back my vision.” —Leitha Harvey

Last year, Leitha Harvey was one of

those deserving patients. A sixty-

four-year-old massage therapist

suffering from advanced cataracts,

she is employed but uninsured and

living with her son. By the time she

was able to get cataract surgery at

Moran, this is how Leitha functioned:

“Co-workers had to clock me in and

out and write out the names of my

clients. I could only see to drive in

the daytime with one eye covered. I

went to work during daylight hours,

but had to come home after dark,

so I covered my right eye to see with

my left and prayed that no one was

coming! I have to say that I crossed

over lines a few times. I’m just really

grateful for the team of workers here

and the people who are willing to

donate to this cause. I didn’t think it

was available for someone like me. I’m

not from Nepal or Africa or the Indian

Reservation, but I find myself in a

position that I need help.”

Dr. Derek J. Sakata, standing; Dr. Bradley J. Katz and surgical team

Dr. Bradley Katz and Leitha Harvey

Fo

cu

s 2

013

24

Fo

cu

s 2

013

25

ANDY’S

“You may encounter many defeats, but you must not be defeated. In fact, it may be necessary to encounter the defeats, so you can know who you are, what you can rise from, how you can still come out of it.” —Maya Angelou

Unexpected Pit Stop

Mike Nish, Andy Nish, and Moran’s Dr. Paul Bernstein

An Innocent Game of Dodge Ball Watching fourteen-year-old Andy Nish cross the �nish line for second place in the 2012 World Junior Karting Cham- pionship at Miller Motorsports Park, you would never know that he accom-plished this feat with a macular hole and detached retina—and neither did Andy! Just as shocking, Andy had been functioning with this catastrophic vision injury for almost two years be-fore he sought help.

�e answer to the obvious question, “How did Andy not know?” is a combination of his utterly youthful resilience and his reticence to complain. “If he did complain, I didn’t hear it,” says Andy’s dad, Mike Nish, “nor did his mother.” It wasn’t until Mike asked, “How come your eye is so red?” and heard Andy’s jaw-dropping reply, “cause I can’t see out of the other one,” that they �nally sought treatment. Recalling

“We can ask other patients to lie face

down for a week, but it is very hard to do

that with an active teenager.” —Dr. Paul Bernstein

past accidents, they realized that Andy had been slammed in the side of the head with a dodge ball two years prior, but because the incident was so long ago and the problem had gone undetected, the injury gradually degenerated to where Andy nearly lost all vision in his le� eye.

Diagnosis “�e severity of the injury to the retina, the hole torn directly in the macula, and complex scar tissue reaction made Andy’s injury signi�cantly complicated and challenging,” says Moran Eye Center’s world-renowned retinal specialist, Paul S. Bernstein, MD, PhD, who specializes in vitreoretinal diseases and surgery, retinal biochemistry, and macular and retinal degeneration.

�e macula is the part of the retina that is responsible for our central vision and ability to see color and �ne detail when looking directly at an object. “Macular holes from trauma are not common in children, but when they occur, they are very severe,” says Dr. Bernstein.

Surgery To heal Andy’s eye, Dr. Bernstein �rst sewed a scleral buckle, a plastic band, around the equator of the eye, which “feels like getting hit in the eye with a pool cue,” remarks Andy. �is relieves tension on the retina and pushes the sclera toward the middle of the eye toward the tear until it heals. Several weeks later, he performed a state of-the-art small-incision vitrectomy to remove the vitreous and scar tissue. Looking through a microscope through Andy’s dilated pupil, Dr. Bernstein used tiny 25-gauge needles to go in through three ports: “One pumps �uid in, one puts a light source in, and one is the actual instrument,” he explains. Several weeks a�er the vitrectomy, Dr. Bernstein �lled the hole in Andy’s macula with silicone oil, which acts like a shock absorber and pushes the retina back in place, allowing the hole to close. �e scleral buckle and silicone oil will stay in Andy’s eye forever.

Tailoring Andy’s Care Dealing with an active young person who plays basketball, wrestles, and races Karts poses a di�erent kind of challenge. “We can ask other patients to lie face

Andy getting a post-surgery checkup with Dr. Bernstein

Andy in the winner’s circle

The Race to Recovery is Longer than Expected, but the Driver Remains Focused “I thought I would have one surgery, and it would be fixed,” says Andy. “My advice to other kids about having to stop the thing they are passionate about—stay as involved as much as you can. Even though I can’t race yet, I coached a five-year-old boy at the track and helped my little sister with her championship race; I can’t wrestle yet, but Dr. Bernstein says I can be a wrestling manager.”

Yet, in treating an undaunted teenager who aspires to follow in his father’s footsteps, who is as tough and resilient as the 2500-horsepower Nitro Hemi engine that powers his family’s Royal Purple Streamliner, and who has almost completely lost the vision of one eye—the biggest challenge for Dr. Bernstein may not be healing Andy’s eye. Indeed, it may be how to steward the transi-tion of a feisty, driven adolescent as he evolves, through introspection, to adopt a very mature, life-changing philoso-phy—that he may have to reformulate his dream.

down for a week, but it is very hard to do that with an active teenager,” says Dr. Bernstein. “While Andy is a very good patient, he is still very limited in his activities. He always wants to know what he can do and when he can go back to sports…to car racing.”

And car racing is in Andy’s blood. Among the land-speed racing community, the name Nish conjures instant recognition. Terry Nish, Andy’s grandfather, and his three sons, Mike (Andy’s dad), Jeff, and T.J., often tout themselves as the world’s fastest family, holding thirteen records set at the Bonneville Salt Flats—all four are in the 300 MPH Club. This year, the Nishes hope to break their own land-speed record, reaching 425 MPH in their “Royal Purple Streamliner.” It is Andy’s dream to follow in their “racetracks.”

“When I get in the car, I’m completely focused,” says Andy. “I run the track through my mind. And when the green flag drops, it is an adrenalin rush. I never feel scared; it is not a priority. I just want to beat anyone who is in front of me. But racing is not easy,” he explains. “The concentration is mentally and physically exhausting. You have to constantly think and strategize about a maneuver two laps ahead.” Andy wants to drive the Streamliner—a hot-rodder’s dream that goes over 400 mph. “That’s what I’ve wanted to do since I was two,” Andy grins. “Drive.”

Andy has endured several more surgeries to remove scar tissue that tugs at his retina, and he has had a cataract removed. Now, “the macular hole is closed, the retina is reattached, and he has pretty good peripheral vision,” says Dr. Bernstein. “But Andy has lost central vision, which he will never completely get back.” “When I close my good eye, I can see your outline,” says Andy. “But I can’t see detail.”

“I’m amazed every time Andy comes in,” says Dr. Bernstein. “We just want him to have a very functional eye, very useful for the rest of his life.”

“My dream is to race Formula One,” states Andy, “if I can’t do that, I’ll be involved in whatever way I can—I stay involved because I need to stay involved.”

The Nish family’s Royal Purple Streamliner

Andy in Kart #82 takes the lead

Fo

cu

s 2

013

26

Balamurali K Ambati, MD, PhD, MBAProfessor of Ophthalmology and Visual Sciences and Adjunct Associate Professor of Neurobiology and Anatomyspecialtiesocular angiogenesis and corneal research

Alessandra Angelucci, MD, PhDAssociate Professor, Ophthalmology and Visual SciencesspecialtyVisual Cortex Circuitry and Function

R E S E A R C H T E A M 2013m o r a n e y e c e n t e r

reSe

arcH

Wolfgang B Baehr, PhD

Professor and Director, Michael M. Wynn Center for Inherited Retinal Diseases; Ralph and Mary Tuck Professor of Ophthalmology and Visual SciencesspecialtiesPhototransduction, the Retinoid Cycle, and Membrane Protein Transport in Photoreceptors; Biochemistry, Molecular and Cell Biology

Paul Bressloff, PhD

Adjunct Professor, Ophthalmology and Visual Sciences; Professor of Mathematicsspecialtymodeling of Visual cortex

Paul S Bernstein, MD, PhD

Director of Clinical Research and Associate Director of Research; Mary H. Boesche Professor of Ophthalmology and Visual SciencesspecialtiesVitreoretinal Diseases and Surgery; Retinal Biochemistry; Macular and Retinal Degeneration

Donnell J Creel, PhD

Research Professor, Ophthalmology and Visual Sciencesspecialtyelectrophysiology

Jeanne M Frederick, PhD

Research Associate Professor, Ophthalmology and Visual SciencesspecialtyRetinal Cell and Molecular Biology

Margaret DeAngelis, PhD

Associate Professor of Ophthal-mology and Visual SciencesspecialtyGenomic Convergent/Systems Biology: approaches in an effort to pinpoint disease causality in age-related macular degeneration, diabetic retinopathy, and rare ocular diseases.

yingbin Fu, PhD

Assistant Professor of Ophthal-mology and Visual SciencesspecialtiesMacular and Retinal Degeneration; Gene Therapy; Phototransduction

Fo

cu

s 2

013

27

Fo

cu

s 2

013

28

Sabine Fuhrmann, PhD

Associate Professor, Ophthalmology and Visual SciencesspecialtiesOcular Development; Retinal Pigment Epithelial Cell Biology

Werner Gellermann, PhD

Adjunct Professor, Ophthalmology and Visual Sciences; Research Professor, PhysicsspecialtySpectroscopy of Living Human tissue

Helga E T Kolb, PhD

Professor (Emeritus), Ophthal-mology and Visual SciencesspecialtyRetinal Anatomy

David Krizaj, PhD

Associate Professor, Ophthal-mology and Visual SciencesspecialtiesRetinal Neurobiology; Calcium Regulation; Glaucoma

Mary Elizabeth Hartnett, MD

Professor, Ophthalmology and Visual SciencesspecialtyRetinal Angiogenesis Relating to Retinopathy of Prematurity and Age-related Macular Degeneration

Bryan W Jones, PhD

Research Assistant Professor, Ophthalmology and Visual SciencesspecialtyRetinal Degeneration Disorders: how those diseases affect the intrinsic retinal circuitry, including the implications for rescue of vi-sion via gene therapy and retinal bionic or biological implants; Retinal Neurotransmission and Neurocircuitry; Metabolomics: for application in understanding physiology and medicine for drug development

Gregory S Hageman, PhD

John A. Moran Presidential Professor, Department of Oph-thalmology and Visual Sciences; Executive Director, Moran Center for Translational MedicinespecialtiesThe Genetics and Assessment of Pathways Involved in the Etiology of Age-related Macular Degenera-tion; Retinal Cell Biology

Building bridges from research to patient careg ges fges fg patient ca

Bradley J Katz, MD, PhD

Associate Professor, Ophthal-mology and Visual SciencesspecialtiesNeuro-ophthalmology; Diseases of the Optic Nerve; Comprehen-sive ophthalmology and Surgery

Julia Kleinschmidt, PhD, LCSWProfessor (Emeritus), Ophthal-mology and Visual SciencesspecialtyOrientation and Support Services for international ophthalmolo-gists training under the moran Eye Center’s International Out-reach Division

Fo

cu

s 2

013

28

Ning Tian, PhD

Professor, Ophthalmology and Visual SciencesspecialtyRetinal Neurobiology

Monica Vetter, PhD

Adjunct Professor, Ophthalmology and Visual Sciences; George and Lorna Winder Professor of Neuroscience; and Chair, Neurobiology and AnatomyspecialtiesRetinal Development, Glaucoma

Haibo Wang, MD, PhD

Research Assistant Professor of Ophthalmology and Visual SciencesspecialtyVascular Biology: abnormal vessel growth implicated in pathological neovascularization in age-related macular degenera-tion, retinopathy of prematurity, and diabetic retinopathy

Richard A Normann, PhD

Professor, Ophthalmology and Visual Sciences; Distinguished Professor of BioengineeringspecialtyArtificial Vision/Neural Prosthetics

Edward M Levine, PhD

Associate Professor, Ophthalmology and Visual SciencesspecialtyRetinal Neurogenesis and Regeneration

Nick Mamalis, MD

Professor, Ophthalmology and Visual Sciences; Co-director, Intermountain Ocular Research CenterspecialtiesOcular Pathology; Comprehensive Ophthalmology; Intraocular Lens Research; Postoperative Inflammation

Robert E Marc, PhD

Director of Research and Distin-guised Professor of Ophthal-mology, John A. Moran Eye Center; Cal and JeNeal Hatch Presidential Endowed Chair in Ophthalmology and Visual SciencesspecialtiesRetinal Neurotransmission and Neurocircuitry; Metabolomics

R E S E A R C H T E A M 2013m o r a n e y e c e n t e r

Jun yang, PhD

Assistant Professor, Ophthal-mology and Visual SciencesspecialtiesCell Biology of Photoreceptors and Retinal Diseases

Barbara M Wirostko, MD

Clinical Adjunct Associate Professor, Ophthalmology and Visual SciencesspecialtiesGlaucoma; Drug and Device Development

Liliana Werner, MD, PhD

Associate Professor, Ophthal-mology and Visual Sciences; Co-director Intermountain Ocular Research CenterspecialtyOcular Biodevices Research including different intraocular lens designs, materials and surface modifications, and interactions with ocular tissues.

reSe

arcH

Fo

cu

s 2

013

29

Fo

cu

s 2

013

30

While it is well known that glaucoma, macular degeneration, and retinitis pigmentosa can cause blindness, many people do not know that 10-15 percent of all blindness in the US is a result of inadequately treated uveitis. “That’s key,” states Dr. Vitale. Uveitis is inflammation of the uvea, the middle layer of the eye, consisting of the iris, choroid,

and ciliary body. Any form of uveitis may be serious and may be a symptom for other serious conditions. “Forty-five to fifty percent of patients will have permanent visual impairment from not being adequately treated,” says Dr. Vitale. “The impact of that blindness is significant because it frequently affects people in their productive prime. So, it is essential to make a diagnosis and to treat uveitis effectively and adequately—to get the inflammation under control to prevent the ocular structural damage to the eye that leads to permanent visual impairment.”

And this is the crux of the disease: “Uveitis can be challenging to diagnose because of its complexity. It can occur by itself or as a feature of an underlying disease,” says Dr. Vitale. “Uveitis is not one disease—it is about 30 diseases.”

The book presents a unique philosophy: “Our mission is remission—a complete intolerance to chronic, even low-grade intraocular inflammation—with no relapse.” The text stresses that physicians follow a comprehensive approach to diagnosing the underlying cause of the patient’s uveitis. This includes collaborating with a trained and truly expert chemotherapist or ocular immunologist about how to use immunomodulatory medications so that the patient does not experience any significant drug-induced side effects. “Use whatever you need, but don’t subject the patient to unnecessary medications just to induce a remission of these diseases—this is a key concept—however you can do that,” stresses Dr. Vitale.

“I’m not against any one therapy, but the approach needs to be individualized to the patient, to their disease, and to what they can or cannot tolerate. It requires knowing the patient very well, medically, ocularly, and personally,” he continues. “If a patient tells you, ‘You know what, I’m going to become a homicidal maniac if you give me systemic steroids,’ I probably won’t do that.”

OUR MISSION IS REMISSION

Second Edition

Diagnosis and Treatment of Uveitis

As the ophthalmic community is rife with uveitis texts and references, how does one become excited about yet another tome…and the second edition at that?

The extraordinary commitment and conscious philosophy of one Moran physician

may be the answer. Please join Moran and the worldwide medical community in

welcoming the second edition of Dr. Albert T. Vitale’s definitive textbook, Diagnosis

and Treatment of Uveitis. The book, noted for its “encyclopedic organization,” was

published in 2012 with co-author Dr. C. Stephen Foster. Dr. Vitale is one of the

only ophthalmologists in the Intermountain West specializing in the diagnosis and

treatment of uveitis and other infections and inflammatory diseases of the eye.

He is also one of a handful of people in the country with dual training in ocular

immunology and inflammatory disease as well as vitreoretinal surgery. He is the

only provider of such expertise in the Intermountain West.

Not only is the book clear about its philosophy, it is comprehensive in scope, offering six sections, 83 chapters, and over 1,200 pages. “There are other books, which are great textbooks, but this is very user-friendly—very readable. I think in broad categories…you’ve got all this information available…you can look here for specifics, in chapters,” explains Dr. Vitale.

“You have to stay in the hunt: if you don’t at first come up with a diagnosis, always evaluate, reassess, and rethink the patient’s response to your treatment. If something isn’t working, try something different to gain control of the inflammation without pro-ducing untoward side effects,” he stresses.

“I believe that we are on the planet to help each other. There is much more that binds us together than separates us if you are awake and attentive to it,” says Dr. Vitale. “I see that every day in taking care of my patients…I really do. They just teach me so much. It is humbling. It is a real privilege to be a physician.”

“I’m totally awed and humbled

by the way in which many of my

patients handle tremendous adversity

and the trust that they put in me. The

burden that they manage is almost

unthinkable sometimes.” —Albert T. Vitale

VIT

ALE

Albert T. Vitale MD, has incorporated his research interests into clinical practice and is focused on novel drugs and delivery systems for the treatment of ocular inflammatory disease, age-related macular degeneration, and diagnostic and therapeutic vitreoretinal surgery in the management of uveitis, pediat-ric uveitis, and the interface between ocular inflammatory disease and age-related macular degeneration.

In addition, he is involved in the delivery of comprehensive and sustainable retinal care in the developing world through the Division of International Ophthalmology at the Moran Eye Center and ORBIS. He also works with the indigent and underserved in Salt Lake City, serving as Medical Director for the Moran Eye Clinic at the Fourth Street Clinic. Dr. Vitale is committed to education, not only among residents and fel-lows at the Moran Eye Center, but nationally and internationally, serving as contributing editor for several American Academy of Ophthalmology publications.

Fo

cu

s 2

013

32

Fo

cu

s 2

013

33

�ere is huge pressure for scientists to report positive �ndings, and historically,

negative results have been harder to publish. However, corrective science is part of the

process—and needs just as much attention. —Bryan W. Jones, PhD

Moran Researchers Upend Prevailing Theories about

RARE CHILDHOOD DISEASE

A commitment to ongoing, intensive vision research with the potential to change millions of

lives sets the Moran Eye Center apart. Keeping Moran at the forefront are creative researchers

like David Krizaj, PhD (pronounced KREE-zhai); Peter Barabas, PhD; Aihua Liu, PhD; Wei Xing;

Ching-Kang Cheng, PhD; Zongzhong Tong, PhD; Carl B. Watt, PhD; Bryan W. Jones, PhD; Paul

S. Bernstein, MD, PhD; and their willingness to question assumptions behind accepted theories.

Case in point: For years, vision scientists believed that a lack of very long-chain fatty acids (VLC-PUFAs) in photoreceptor cells caused blindness in children with Stargardt type 3 retinal degeneration. Stargardt, an incurable eye disease, is a form of macular degeneration that strikes about one in ten-thousand children between the ages of six and twenty. The severity and progression of the disease varies widely, but vision loss is most intense in the macula, in the center of the retina. Some peripheral vision may remain, but visual acuity can decline to 20/200 or slightly worse, rendering children legally blind.

Three types of Stargardt are caused by three different gene mutations: ABCA4, CNGB3, and ELOV4. Scientists have long thought that type 3, the rare and autosomal dominant form of the disease, is caused by defects in the gene ELOVL4. (Moran’s Dr. Paul Bernstein, retinal specialist and professor of ophthalmology and visual sciences, was one of the original discoverers of the ELOV4 mutation, having characterized it in a Utah family.) However, ongoing studies and results regarding Stargardt type 3 have actually been somewhat contentious. According to Dr. Krizaj, “The prevailing theory about long-chain fatty acids has always been up for dispute because, for one thing, scientists were unable to generate an animal model of the disease—mice in which ELOVL4 was knocked out did not survive.”

To Dr. Krizaj and his team, the challenge was academically fascinating as well as motivating. “While the focus in our lab is on photoreceptor cells—mainly their physiology—we thought we had a shot at providing a more definitive theory as to what the mechanism underlying this devastating disease might be,” he explains. “If we can understand its causes, we can possibly find treatments to first delay and then maybe prevent it from manifesting.”

Engineering Change By actually breeding a better mouse, the researchers disproved the prevailing theory. Our models lacked ELOVL4 only in their photoreceptor cells, allowing the mice to survive, but with the fatty acids in those cells reduced up to 90 percent. This allowed them to test directly whether loss of very long-chain fatty acids replicates vision loss in children with Stargardt disease. Electrophysiological and behavioral testing of day and night vision in the mice showed that sight was not affected despite the dramatic reduction in very long-chain fatty acids in photoreceptor cells. The group published its findings in PNAS online, March 11, 2013. Peter Barabas, PhD, a postdoctoral fellow in Dr. Krizaj’s group, is the first author on the study.

As a result, the research community experienced a “one-step-back” moment—which, according to Dr. Krizaj, “means that a set of proposed treatment strategies can be set aside, and we can start thinking of new possibilities. One is that mutated proteins escaping from the endoplas-mic reticulum are aggregating in the cytoplasm, a jelly-like substance in the cell, and resulting in large deposits of mutated and normal proteins. This is almost like causing photoreceptor cell death by blocking intracel-lular traffic and clogging the cells’ drains,” Krizaj notes.

Going Forward While the published study constituted a breakthrough moment, mouse models are by no means perfect replications of human Stargardt type 3. Moran researchers have a solution. “Humans rely on cone photoreceptors much more than rods during the daytime,” explains Dr. Krizaj. “Mice are basically nocturnal, so they have just a small percentage of cones. Our mouse models are closer replicas of the human Stargardt disease. We have submitted a grant with Dr. Bernstein to the Foundation Fighting Blindness and will eventually go to the National Institutes of Health to pursue the grand question: what is the best way to first delay and then prevent Stargardt type 3?”

A scan of a patient’s retina with Stargardt Disease, or fundus �avimaculatus, an inherited form of macular degeneration that causes progressive vision loss and blindness. �is retinal scan is projected on top of the retina of a mouse model in red and green, designed to let scientists at the Moran Eye Center study some of the mechanisms of the disease.

Photo credit: Bryan William Jones, PhD

Paul S. Bernstein, MD, PhD, David Krizaj, PhD, Bryan W. Jones, PhD, and Peter Barabas, PhD

Fo

cu

s 2

013

34

Premature babies born weighing less than 2-3/4 pounds have always been at risk for ROP because the retina is not fully developed until full term. But because technology to save ever smaller and younger preterm babies has developed throughout the world, ROP has become a leading cause of infant and childhood blindness worldwide. “I’ve been examining babies and treating them with laser and surgery for over 20 years. �e gestational age of preterm infants who survive to develop ROP has become younger, and the appearance of ROP has changed with this. However, in developing countries outside the US, older and larger preterm infants

Retinopathy of prematurity is a vision-threatening disease caused by abnormal development of the retinal blood vessels, whereby instead of growing into the retina, the blood vessels start to grow into the vitreous gel where they bleed and form scars. Retinopathy of prematurity occurs only in premature infants and is the subject of a Medical Progress Report by Dr. Hartnett and co-author John Penn, PhD, of Vanderbilt University, published in the New England Journal of Medicine, December 27, 2012.

Mary Elizabeth Hartnett, MD

are developing ROP in part because the resources to regulate oxygen are lacking. Many of these infants are developing ROP similar to what occurred in the US in the 1950s,” she says.

“When ROP was �rst recognized in the US, it was thought to manifest because of the amount of oxygen that was being given to preterm babies—100 percent in some cases—which injured the babies’ newly developing endothelial cells. But with the ability to regulate oxygen to preterm infants, our perspective has since changed: initial descriptions may have represented a di�erent form of ROP than we see now

M������ P������� R�����:

S H E D D I N G

New Light on Retinopathy of

Prematurity

If there is any way to avoid the need for vitreoretinal surgery on a preterm baby, Dr. Mary Elizabeth Hartnett is

determined to �nd it. “�e safe area to enter the eye of a premature baby is less than a millimeter wide. Outside of that, you could

damage the tiny lens or injure the retina, which could lead to inoperable retinal detachment,” she says. “Obviously, the stakes are

incredibly high.” And yet, there have been cases in which Dr. Hartnett, who specializes in pediatric and adult retinal diseases and

surgery at the Moran Eye Center, has had to operate on preterm infants whose gestational and chronologic age combined was

under term birth. �ese infants were experiencing retinal detachments from retinopathy of prematurity (ROP). Fo

cu

s 2

013

35

PEDIATRIC RETINA CENTER AT MORAN Whether an infant experiences surgery for the most progressive stages of ROP or develops a milder form that eventually resolves on its own, infants with ROP are considered to be at higher risk for developing certain eye problems later in life, such as retinal detachment, myopia (nearsightedness), strabismus (crossed eyes), amblyopia (lazy eye), and glaucoma. In many cases, these eye problems can be treated or controlled, but as Dr. Mary Elizabeth Hartnett points out, “Doctors and parents must be constant advocates for these kids. It is so important.”

The Pediatric Retina Center at Moran is equipped to diagnose and treat these and myriad other conditions, including rare situations specific to children. Moran’s highly specialized team has the capacity to perform vitreoretinal surgery and offers diagnostic testing, such as electroretinography (which measures the function of the retina since very young children can’t read a chart), consultations, and visual rehabilitation. The team also consults with people who can’t make it to the clinic or with their doctors. The center has the potential to become a hub of services and resources in the inter-mountain region.

The Pediatric Retina Center at Moran can also be of particular help in small or rural areas that may not have pediatric retina specialists by bridging the gap between what doctors and patients know about pediatric retinal conditions and what can be done, including vetting the best websites, providing reliable information and images, and consulting with doctors nationwide.

that oxygen is regulated,” Dr. Hartnett explains. “Rather than injuring already developed retinal vessels, we see that normal retinal vessel development is slowed down, and instead, vessels grow abnormally from the retina into the normally clear gel that �lls the back of the eye. �ese vessels are fragile and can leak, causing bleeding into the eye. As a consequence, scar tissue may develop and pull the retina loose from the eye’s inner surface. In severe cases, this results in loss of vision.

“It is really di�cult to research ROP. In the infant, especially a premature one, taking any �uid from the eye is extremely risky and can lead to blindness. And of course, preterm infants don’t have a lot of blood, so taking too much blood is avoided. Consequently, we study ROP by using mouse models,” Dr. Hartnett

explains. “From the 1940s–60s, there was a mouse model of oxygen-induced retinopathy using high oxygen to examine the cellular and molecular mechanisms that drive the progression of pathologic changes in ROP. But the mouse model really doesn’t re�ect most of the ROP we see in the US today. A number of technical advances have occurred so that we can regulate and monitor the oxygen levels of babies, but in a disease where we are limited as far as what we can do in the human infant, we really need to use relevant animal models to be able to study the disease. �at was the �rst part of our article,” she says. “In the second part, we described various pathways that appear to be important using a rat model developed by John Penn that may lead to treatments for ROP.”

As the article points out, this is a �eld in �ux, with a number of dilemmas. Some treatments, such as anti-vascular

endothelial growth factor (VEGF) injections that seem to help may also have adverse e�ects (this topic is explored in recently published papers from Dr. Hartnett’s lab). “What makes it hard is that there are so many things going on with preterm babies. We are dealing with issues of development as well as the disease,” she notes. “Sometimes factors, such as VEGF, that cause pathologic features of ROP are also important in the development of the preterm infant. As we understand more of what’s going on in preterm babies with ROP, we will be able to better treat the disease, improve visual development, and hopefully, avoid the need for surgery.”

Mary Elizabeth Hartnett, MD, Professor, Department of Ophthalmology and Visual Sciences at the Moran Eye Center,

was awarded the Honor of Silver Fellow, 2013, by the Association for Research in Vision and Ophthalmology for her work as

a role model and mentor for people pursuing careers in vision and ophthalmology research. She was also recently selected

for a prestigious post with the National Eye Institute at the National Institutes of Health as Chairperson to the Diseases and

Pathophysiology of the Visual System Study Section at the Center for Scientific Review, 2013. As chair, she will be leading

one of the main translational eye study sections that reviews grants for the National Eye Institute.

Fo

cu

s 2

013

36

S E C o N D y E A R

Fellowship P grFellowship P grFellowship PFellowship PrFellowship P grFellowship PrFellowship P ogroFellowship P oFellowship P grFellowship P oFellowship Pror grrorFellowship PrFellowship P oFellowship PrFellowship P grFellowship PrFellowship P oFellowship PrFellowship P am 2013-2014gram 2013-2014gr

Luis Santiago-Caban, MD

C O R N e a

R E T I N A

G L a u C O M a

ResidencYResidencYResidenc PY PY gr P gr P Pr P gr Pr P ogro P o P gr P o Pror grror Pr P o Pr P gr Pr P o Pr P am 2013-2014gram 2013-2014grF I R S T y E A R

Adam Jorgensen, MD Brian Stagg, MD Russell Swan, MD

Zachary Joos, MD Trent Richards, MD Brian Zaugg, MD

T H I R D y E A R

Valli Muthappan, MD

Ronald Hobbs, MDNikhil Batra, MD

Meng Lu, MDJoseph Chen, MDDan Bettis, MD Leah Owen, MD, PhDJim Bell, MD

Ophthalmology training at the highest levels2012 ushered in an innovative education model at Moran—a “Resident Continuity Clinic” in which future

ophthalmologists start seeing patients on day one, under the supervision of a board certified ophthalmologist.

R E S I D E N T S A N D F E L L o W S

2013-2014m o r a n e y e c e n t e r

Krista Kinard, MD

Benjamin Thomas, MD

NEURo-oPHTHALMoLoGy

MORaNINTERNATIoNALFELLoWSHIP

Fantastic program, hospital, university, and location With 12 locations and four state-of-the-art ophthalmic surgery suites, over 40 ophthalmology specialists carry out more than 8,000 surgeries per year. The Moran Eye Center benefits from sufficient patient visits (120,000/year) to ensure a full spectrum of clinical and surgical experiences for both residents and fellows. The Moran residency and fellowship programs are crafted to mesh perfectly and to enhance the education of each individual specialist who we train.

the Department of ophthalmology and the moran eye center are key components of the 400-bed University Hospital and its satellite clinics. This includes more than 1,200 board-certified physicians staffing four University hospitals. Consistently ranked among US News & World Report’s “Best Hospitals,” we also “Best Hospitals,” we also “Best Hospitals,”provide training at the 131-bed Veterans Administration Medical Center and Primary Children’s Hospital.

Located at the base of the spectacular Wasatch Mountains, the University of Utah is the flagship institution of higher education in Utah. With world-class skiing, gorgeous desert country, and a population known for friendliness, Salt Lake continues to be ranked among the top cities in which to live—all factors contributing to making the postgraduate positions available at the John a. moran eye center a superb overall experience.

I N T E R N S A N D PAT H o L o G y F E L L o W Sm o r a n e y e c e n t e r

2013-2014InterInterInte ns & Ocularns & Ocular rns & Ocularns & Ocula Patholor Patholor gy Pathology Patholo Fellows 2013-2014gy Fellows 2013-2014gy

Eileen Hwang, MD, PhD Julia Byrd, MD Rene Choi, MD, PhD

Scott Cole, MD Joshua Ford, MD Justin Kohl, MD

I N T E R N S

o C U L A R P A T H o L o G y / R E S E A R C H

Fo

cu

s 2

013

38

Fo

cu

s 2

013

39

Moran’s New Resident Continuity ClinicDay One: Meet Your Patient

Dr. Je� Pettey examines Fourth Street patient

Aabid Faruukhi, U of U medical student with a Fourth Street patient

Drs. Russell Swan, Zachary Joos, Krista Kinard, Jim Bell, Trent Richards, Derick Holt, Leah Owen, Dan Bettis, Brian Zaugg

2012 ushered in an innovative education model at Moran—a “Resident Continuity Clinic” in which future ophthal-mologists start seeing patients on day one, under the supervision of a board certified ophthalmologist.

Day One: Meet Your Patient Taking the helm as new residency program director and striving to continue to provide the most progressive, forward-thinking resident program, Dr. Jeff Pettey, Assistant Professor and As-sociate Program Director of Ophthalmology and Visual Sciences, evaluated current academic ophthalmology practices and models in the United States and worldwide, focusing on cutting-edge innovations in training and teaching. He found that residents may miss out on some important aspects of training that occur when a patient identifies a doctor as their primary eye care provider. As a result, he established a resident-staffed model “Continuity Clinic,” which provides opportunities for residents to follow patients during their training under the supervision of a board certified ophthalmologist. “The clinic provides a unique teaching environ-ment and an opportunity for residents to learn how to become the

provider for the patient in a well-supervised setting with graduated levels of responsibility, beginning day one,” says Dr. Pettey. “This is an opportunity for residents to really personalize their training.”

It begins as residents examine patients and propose a diagno-sis. Dr. Pettey also examines the same patients, teaching the residents throughout the process. Senior residents are able to diagnose and come up with a treatment plan, and Dr. Pettey then compares it with his own plan. For example, “We had a really complicated patient who had been to emergency two times then

Moran’s continually rising reputation and state-of-the-art graduate training program has resulted in a record-high increase in the number of resident applications received to date. “We just �nished interviewing 28 applicants out of 400 top-tier candidates and submitted our matches; it’s very exciting,” said Dr. Je� Pettey. �is year, the competition was more intense than ever.”

—Dr. Je� Pettey, January 2013

Dr. Tom Oberg, resident

came to the clinic with signs of a viral infection. He had a blood clot in his brain that would have killed him if not properly di-agnosed. A resident put the clues together—he knew exactly where the clot should be—and we sent him back to emergency for tests, literally saving his life. I’m frequently humbled that the residents’ level of knowledge is at times equal to or surpasses mine,” Dr. Pettey notes.

During clinics, residents see their own patient for the entire course of the patient’s treatment. Because the Continuity Clinic sees a low volume of patients—an average of six to ten per day—Dr. Pettey is able to take more time to teach, residents get more time with patients, and care is highly personalized. Some of the clinic’s patients are University Hospital in-patients who have complex medical problems and may come to Moran if they are medically stable. Others are seen at the Fourth Street Clinic as part of Moran’s local outreach efforts. Issues may range from loss of vision to diabetes to stroke, so residents get a range of experience. Interns see patients for one-half day each week, increasing patient time as they advance each year. Residents assist in surgery for the first two years and transition to primary surgeon their third year, when they apply to subspecialty fellowships—again, always under the supervision of a board certified ophthalmologist.

“I believe in finding the joy in every challenge, in every success,” says Dr. Pettey. “I get personally attached to the residents’ success—to get them to connect and see the vision—I’m still teaching, but the process is much more rewarding than a one-way teacher-student relationship. I learn from them every day.”

Fo

cu

s 2

013

40

A Clear Vision of ServiceMoran Resident Brian C. Stagg, MD, is Already Making a DifferenceIt’s no surprise that twenty-nine-year-old Moran resident Brian C. Stagg, MD, had plenty of choices when he was deciding on a residency program. In addition to having a decade of service projects, teaching, research, and publications to his credit, his resume includes a Bachelor of Science in Neuroscience and a minor in Portuguese with honors from Brigham Young University and a medical degree from the University of Utah. “I looked into several possibilities and found that the amount of experience residents get at Moran is really far above average—as is the faculty,” he says. “In most places, you don’t get an intern year with a lot of experience in ophthalmology, but with Moran’s Continuity Clinic we get a very special experience that includes building patient relationships.”

Dr. Stagg is as fascinated by the eye as he is motivated by build-ing relationships. Even before he entered the residency program, Stagg was deeply involved with Moran’s ongoing, monthly out-reach at Salt Lake’s Fourth Street Clinic—a free clinic that provides comprehensive healthcare to the city’s homeless population. He coordinated volunteers and managed the clinic, doing every-thing from scheduling appointments to making sure patients who needed further treatment actually made it to Moran and had a place to stay after surgery, if needed. When Moran doctors visited the clinic to help patients with issues from cataracts to diabetes, Stagg made sure that everything was set up and ready so they could go straight to work.

Now, he’s also a member of the team examining patients. “The chronically ill are a special challenge,” he notes. “I’m working on setting up special blocks of time for them because I think we can make a big difference and run the eye clinic more efficiently.” He also plans to help find ways to put better equipment in place and add another lane for examinations. “I like coming up with solutions, not staying with the status quo. Teaching, research, having a practice—I want to do it all.”

“I like coming up with solutions, not staying with the status quo. Teaching, research, having a practice—I want to do it all.”

—Brian C. Stagg, MD

Dr. Jeff Pettey, Hector Monjaras, Dr. Brian C. Stagg

Dr. Grant Morshedi, Kevin Kirk, U of U fourth-year medical student at Fourth Street Clinic

Brian C. Stagg, MD, received the 2013 Scholar Award from the Achievement Rewards for College Scientists Foundation Inc. (ARCS). The foundation’s mission is to “advance science and technology in the US by providing financial awards to academi-cally outstanding US citizens studying to complete degrees in science, engineering, and medical research.” Only US universi-ties whose departments are ranked in the top 100 in the country are eligible to receive ARCS Foundation Scholar Awards.

Fo

cu

s 2

013

41

Moran eye Center in your Community The Moran Eye Center provides comprehensive eye exams, fashion eyewear, and the latest contact lenses to meet all of your eye care needs. We have 13 locations along the Wasatch Front. Moran Community Clinics are typically located with a University of Utah Health Care Clinic, which provides a full range of world-class medical services.

2013m o r a n e y e c e n t e rC o M M U N I T y C L I N I C S

Moran Eye Center Doctors of Optometry

Robert Corry, OD

Timothy Gibbons, OD

Mark McKay, OD

Alan Morgan, OD

Harald Olafsson, OD

Clair Palmer, OD

Colleen Schubach, OD

Craig Smith, OD

Bryan Vincent, OD

Fo

cu

s 2

013

43

A self-described “spunky” ninety-�ve-and a-half-year-old, Elizabeth says she is “simply ecstatic” about her gi�, the matching donation, and the fact that David’s name will live on in Moran’s mission of providing hope, understanding, and treatment to all. In her words, “�e sight-saving work that Moran is doing all over the world and right here in Utah, in the Navajo Nation, just blows my mind!” Starting with their next mission to Nepal in October, Moran teams will carry and unfurl a huge banner with David’s face and name on it. �ey will �y the banner at each eye camp that they establish, eventually covering twenty-two countries on six continents.

Elizabeth’s Story Born in North Carolina in 1917, Elizabeth was just two years old when her mother passed away and she was sent to live with relatives in Salt Lake City. While it wasn’t the happiest childhood, she says she seems to have been “born with some kind of spunk inside—and a good dose of integrity and ability to see the true nature of people.” As a young “Tri Delt” at the University of Utah, she met and four years later married Raymond Irvin Johnson, an outstanding head-of-his-class “Pi Kap.” True to her ability to discern a person’s nature, she had fallen in love with a man who would become one of Utah’s most successful businessmen. �e youngest person ever to pass the CPA exam at age 22, Raymond was immediately snapped up by the FBI where he worked as a special agent, using his expertise to uncover a number of illegal �nancial schemes. A�er he resigned from the FBI, he started his own construction �rm—the largest in Marin County, California and nearby Lake Tahoe. A�er 20 years, he closed the construction �rm. “But he stayed active in the �nancial world, saving both Alpine Meadows and Park City Ski and Mountain Resort from bankruptcy,” says

Elizabeth. �roughout their marriage, Elizabeth took immense pleasure and pride in planting and nurturing her lush gardens, creating warm and welcoming homes, and traveling the world.

David’s Legacy She punctuates her conversation with smiles and twin-kling eyes, constantly gesturing with her delicate hands and eliciting laughs with pointed comments—and not much gets past her. But to this day, Elizabeth still has to stop and take a deep breath when she contemplates the sad and senseless loss of her grandson over 30 years ago. When he was just eight years old, David was hit and killed by a drunk driver while standing on the sidewalk on the street corner of Main Street in Salt Lake City. �at tragedy forever changed and a�ected Elizabeth; she has been a relentless crusader against drunk driving ever since. “I want people to know about what happened to David, and to remember it,” she says. “Please, do not drink and drive.”

Game-changer International Division Manager Michael Yei notes, “Elizabeth’s incredibly generous gi� is a true game-changer. �e David Kelby Johnson Hope Fund will allow us to expand our programs into new areas of desperate need— it will bring more sight-saving surgeries to so many more blind patients in some of the most neglected and underserved regions of the world, and it will give us a springboard for more long-term, sustainable programs.”

“I’ve always stood up for what I believe in,” Elizabeth is fond of saying. “And I really believe in Moran. �is gi� will help so many desperate young people to restore their sight and give them hope for a brighter future. David would be so delighted to know that he will forever be a part of that.”

When Elizabeth Hope Johnson of Salt Lake City dreams, she dreams big. One of her wishes has always

been to honor and share the memory of her late grandson,

David Kelby Johnson. In 2013 she made that wish come

true with an extraordinary, heart-felt donation to Moran’s

ongoing outreach programs—locally and around the world.

The center’s namesake, John A. Moran, matched her

donation of one million dollars, and Mrs. Johnson happily

christened it the “David Kelby Johnson Hope Fund.”

David Kelby Johnson

A Grandson’s Legacy and a Game-changer for Moran’s Outreach Program

HOPEFUND

David Kelby Johnson

Fo

cu

s 2

013

44

John A. Moran met Sam Skaggs in 1962 when Mr. Moran was a young investment banker just getting started. “Sam helped me complete my first financing transaction with the investment firm I joined after I’d been released from active duty in the navy,” Mr. Moran recalls fondly. “It meant a lot to me and boosted my confidence. I have never forgotten Sam’s belief in me and his longtime support. I consider him one of my dearest friends.”

Dr. Olson recalls a critical gift from the Skaggs family: “Two-and-a-half years after John Moran gave his lead gift toward the new 210,000-square-foot Moran Eye Center, Moran needed another major gift to begin construction. Sam Skaggs and The ALSAM Foundation stepped up with that second major gift, making it possible to construct our beautiful new eye center in 2006.”

The six-story L.S. and Aline W. Skaggs Research Pavilion at the Moran Eye Center unites more than 60 PhD vision researchers who were once scattered around the University of Utah Campus. It is also connected by bridges to our clinical facilities, symbolizing our desire to bring research discoveries to patient care as quickly as possible. These state-of-the-art research laboratories are helping to recruit top new scientists to Moran. Sam’s generosity is literally speeding up research that is bringing us closer to treatments and cures for vision loss.

Most recently, The ALSAM Foundation provided a generous donation for Moran researchers to work with Native American populations in Utah, a lifelong passion of Mr. Skaggs who felt a desire to help America’s underserved tribes. This donation is funding Moran molecular biologist and geneticist Dr. Margaret DeAngelis and her team as they carry out research

This year faculty, staff, and friends of the John A. Moran Eye Center lost a dear friend and generous

benefactor in the passing of Sam Skaggs. Dr. Randall J Olson, Chair of Ophthalmology and CEO of the

John A. Moran Eye Center, said this about Mr. Skaggs: “Sam Skaggs and John Moran have been spe-

cial friends throughout their lives. With Sam’s passing, we all feel we’ve lost a friend. Not only was he a

remarkable businessman, he was a dedicated husband and father. Sam and his dear wife Aline worked

hard and saved their money to create a better world through philanthropy. We see these same principles

mirrored in the lives of their children.”

The Expanding, Enduring Legacy of

“Let no one weep for me, or celebrate my funeral with mourning; for I still live, as I pass to and fro through the mouths of men.”—Quintus Ennius

Sam Skaggs

John A. Moran

L. Sam Skaggs

Moran Eye Center construction 2005

into retinal diseases among Native Americans. As Moran researchers carry out this program of research, we have been privileged to witness firsthand the legacy of giving that Sam Skaggs instilled in his children. Before his passing, Mr. Skaggs was delighted and proud to learn that his daughter Claudia was working alongside Dr. DeAngelis to ameliorate retinal disease in this population. Following in her father’s footsteps, Claudia is committed to quiet philanthropy and service and continues to donate her time to this program.

If Sam Skaggs could speak to us today, one wonders if he might echo the wish of Quintus Ennius and say: “Let no one weep for me, or celebrate my funeral with mourning; for I still live, as I pass to and fro through the mouths of men.”

The Philanthropy of Sam and Aline Skaggs

Making the world a better place for generations to come

Sam and Aline Skaggs have bestowed a legacy of giving personally and through The ALSAM Foundation and other entities they founded over the past 65 years. They have given hundreds of millions of dollars to education, health care, and research by way of scholarships, the establishment or funding of many university and research centers, and the nation’s largest single parochial elementary and secondary complex, located in Salt Lake City.

Six major universities have named either their pharmacy school or a building housing their pharmacy school after Sam and Aline due to their generous funding. Mr. Skaggs gave one of the largest gifts ever made to medical research for the creation of The Skaggs Center for Chemical Biology at The Scripps Research Institute.

Many universities and colleges have recognized the important effect Sam Skaggs has had on education. As early as 1970, he received a citation from the University of Utah that captures his spirit of giving: “To Mr. L.S. Skaggs, Jr., distinguished native son of the West, dynamic personality, and capable administrator in the distribution of pharmaceuticals and health care needs, leader in the intricate and competitive world of business, friend of education and research as the key to our successful future.”

The crown jewel representing Sam Skaggs’ commitment to education, health care, and research at the University of Utah is the new L.S. Skaggs Pharmacy Research Institute, which connects to the older pharmacy building constructed in the 1950s to honor Sam’s father. The joining of two buildings into one great school demonstrates the father/son commitment to education over 60 years. We’re proud to say that John Moran was a key donor to the L.S. Skaggs Pharmacy building.

Claudia Skaggs Luttrell and Dr. Margaret DeAngelis

John A. Moran Eye Center

L.S. Skaggs Pharmacy Research Institute

Fo

cu

s 2

013

45

Fo

cu

s 2

013

46

Fo

cu

s 2

013

47

Second Suns: “Required reading for anybody with an interest in humanitarian philanthropy…”—Outside Magazine

moRan’s DRs. GeoFFRey taBIn anD sanDuk RuIt

featured in New Book

Drs. Tabin and Ruit have dedicated their time and efforts to eliminating preventable blindness in the world by developing a revolutionary ten-minute surgery that costs about twenty dollars. Their system includes building self-sustaining hospitals in emerging nations and training local doctors who then train other local and international doctors in this surgical process. To date, Drs. Tabin and Ruit are directly or indirectly responsible for restoring sight to more than 1 million individuals in some of the world’s most isolated and impoverished nations, including those in the Himalayas and Sub-Saharan Africa.

Moran’s Role in a Sustainable Eye Care Model The Moran Eye Center sends ophthalmic surgeons on multiple international sight-restoring medical missions every year, including some of those featured in Second Suns.

Doctors from around the world are brought to the Moran Eye Center to observe and train with Moran ophthalmology specialists where they learn advanced techniques for restoring sight. They then go back to their home countries to perform these surgeries and to teach local physicians the same sight-restoring skills.

“Ninety percent of cataract blindness occurs in developing countries where such a curable affliction can actually lower the life expectancy by one-third,” said Tabin. “I’m proud to say that for the first time in history, we are witnessing the number of individuals with blinding eye diseases go down each year wherever our system is in place.”

Since its release June 18, 2013, Second Suns has been featured in hundreds of national and international broadcast, print, and electronic, media. Outside Magazine states that “Second Suns should be required reading for anybody with an interest in humanitarian philanthropy—or, for that matter, a desire to feel a little better about the world.”

The dedicated sight-restoring work of Moran faculty members Drs. Geoffrey Tabin and Sanduk Ruit, is chronicled in Second Suns, a recently released book by New York Times bestselling author David Oliver Relin. Dr. Tabin is Professor of Ophthalmology and Visual Sci-ences and Co-director of Moran’s International Division, specializing in corneal, cataract, and refractive care. Dr. Ruit is Adjunct Professor of Ophthalmology at the Moran Eye Center and Medical Director of the Tilganga Eye Centre in Kathmandu, Nepal. Relin’s captivating book tells the story of both doctors’ work to develop and improve eye-care delivery and to help cure preventable blindness in developing countries across the globe.

Drs. Sanduk Ruit, Randall J Olson, Geoffrey Tabin

contentSDonor Report 48

Appointments Honors and Awards 54

Industry Leadership and Service 56

Clinical Trials 62

technology commercialization and Intellectual Property/Patents 64

Grand rounds 66

Published Research 68

Research Grants and Contracts 72

national and International Presentations 79

APP

END

ICES

Fo

cu

s 2

013

48

Fo

cu

s 2

013

49

gifts of $50,000 a n d a b o v e

Frank E. Delvie*

Willard L. Eccles Charitable Foundation

Alan J. Hirschfield

Ben B. and Iris M. Margolis Foundation

gifts of $25,000 a n d a b o v e

Avis Badami

Bamberger-Allen Health & Education Foundation

Bausch & Lomb

Wattis Dumke Foundation

IVEENA LLC

Elizabeth A. Johnson

Noel and Florence Rothman Family

gifts of $10,000 a n d a b o v e

Allergan, Inc.

ARCS Foundation Inc., Utah Chapter

Richard D. Bass

John I. and Toni F. Bloomberg

Brindle Foundation

Kathleen Digre, MD and Michael Varner, MD

Fred W. and Christine A. Fairclough

The Good Works Institute Inc.

Hoya Medical Singapore PTE LTD

Stephen A. and Elizabeth M. Huish

Stephen C. and Lynda M. Jacobsen

Robert A. and Joan Judelson

Gordon M. and Marcia* Olch

Rayner Intraocular Lenses LTD

Richard A. and Carmen Rogers

Snowbird Ski & Summer Resort

Denise R. Sobel

Strazza Family Trust

Hank and Sally Tauber

Jack C. Taylor

Susan O. Taylor

Utah Lions Foundation

James W. and Jeanne J. Welch

gifts of $5,000 a n d a b o v e

Alcon Laboratories Humanitarian Services

Balamurali K. Ambati, MD, PhD

Anew Optics

Bonnie Barry

Kurt Bestor

Dale A. and Janeel O. Burningham

William H. and Patricia W. Child

The Lawrence T. and Janet T. Dee Foundation

Errol P. and Sonja Chesley Eernisse

William K. and Fern H. England

Chase T. Hibbard and Emily L. Stonington

The Jarstad Family

Johnson Foundation

G. Frank and Pamela M. Joklik

Paul Joos, MD

James M. and Alison R. Luckman

Vicki B. Merchant

Herbert I. and Elsa B. Michael Foundation

Ralph P. and Marge L. Neilson

Kirk and Linda Nobis

Margaret D. Ordway

Powervision, Inc.

Rafati Foundation

DonorsThe following individuals and organizations contributed to the Moran Eye Center from January 1, 2012 through December 31, 2012

J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2

2012

gifts of $1,000,000 a n d a b o v e

John A. and Carole Moran

gifts of $500,000 a n d a b o v e

The ALSAM Foundation

Edmund W. and Carol B. Dumke

gifts of $100,000 a n d a b o v e

John B. and Geraldine W.* Goddard

Val A. and Edith D. Green Foundation

Helen K. and Arthur E. Johnson Foundation

Sylvia Prahl-Brodbeck

Hazel M. Robertson

Khosrow B. and Ghazaleh Semnani

Lincoln Shurtz and Lisa Harrison

West Jordan Lions Club

Linda Lewis Wolcott and J. M. Steele

gifts of $1,000 a n d a b o v e

Aaren Scientific, Inc.

George M. Ahn

G. W. and Ida Lee Anderson

N.L. and David R. Anderson, MD

Dan Bass

Raymond E. and Janette H. Beckham

Joseph C. and Gainor L. Bennett

William F. and Victoria F. Bennion

Bennion Jewelers

Ann and Paul Bernstein, MD

BMW of Murray

Bob Bonar

Rodney H. and Carolyn H. (Mitzi) Brady

Eveline Bruenger

Timothy L. Byers, MD, PhD

Laura D. Byrne

Robert A. and Ann Janette L. Carlson

Robert S. Carter Foundation, Inc.

Irene G. Casper

Robert Cionni, MD

Whitney O. and Frances R. Cluff

Kenneth D. Collins

Julie Crandall and Alan S. Crandall, MD

F. Anthony and Joyce G. Crandall

Robert W. and Carol N. Culver

CycleSmith

de Conde’s

Tim and Candace Dee

Barbara S.* and George L. Denton, Jr.

Cameron Brady Diehl

Larry A. Donoso, MD, PhD

Porcupine Pub & Grill

Linda Rankin, PhD

Richard F.* and Jan Rasmussen

Raymond James Charitable Endowment Fund

Ron and Carolyn Reaveley

The Regence Group

Edward N. and Carol S. Robinson

Rockwell Collins

Michael and Bonnie Rothman

Clough and Kay Shelton

Howard S. Spurrier, DDS

Tom and Kristin Stockham

Strong Audi

Blake E. and Cindy Ann Strong

Brad D. Strong

O. C. Tanner Company

Tueng T. Shen, MD and Jan H. Thijssen

Yvette S. Ungricht

James H. and Rolande K. Vaughn

M. Walker and Sue R. Wallace

WanSutter Insurance

Anna M. and Jeffrey R. Weis, MD

Weis Eye Center, PA

Luree and Robert C. Welch, MD

Thacher W. White and Doris Blazek-White

James R. and Linda R. Wilson

Terry L. Wright

Louise and Norm A. Zabriskie, MD

Robert C. and Patience Ziebarth

gifts of $100 a n d a b o v e

Abel Automatics, Inc.

G. Howard Abplanalp

Ann Acaya and Greg Balch

Curtis E. Ackerlind, Jr.

Joel Adams Photography

Jean W. Adamson

Jess and Olivia Agraz

E. R. (Zeke) and Katherine W. Dumke

Jane Durcan, MD and John Hoffmann, MD

Eye System Inc.

Michael A. and Muffy M. Ferro

Carol W. and John H. Firmage III

Joan B. and John H. Firmage II

Cecelia H. Foxley, PhD

Friberg Fine Art, Inc.

Angela and Michael T. Furlong, MD

Nicholas and Courtney Gibbs

Jason A. Goldsmith, MD

Adrienne Graves

Leah Hatziathanasiou and family

C. Charles and Elise Hetzel

Carolyn S. and Robert O. Hoffman, MD

Ann Hollowell

Howard Rodney Horinbein

Alan E. and Drue B. Huish

Frank J. and Sarah G. Johnson

Brad, Tracey, Sam, Jonah, and Zev Katz

Ace Kvale

Mihail S. Lari and Scott E. Murray

James C. Lewis, JD and Carol L. Jent

Marmot Mountain LLC

Beth A. and Edward M. McGill, MD

Ambrose P. McLaughlin, III, MD

Peter R. and Kathy R. Metcalf

Valerie A. and Mark D. Mifflin, MD

Corey A. and Nancy J. Miller

Ruth A. Morey

G. Mitchell* and June M. Morris

Michael V. and Paula F. Morris

Mimi B. Mortensen

John J. Moy

George G. and Pauline Mulligan

Marilyn Olson

Ruth L. Olson and Randall J Olson, MD

Outdoor Research

J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2

Fo

cu

s 2

013

50

Fo

cu

s 2

013

51

Steven and Susan Dewey

T. Jerald and Carol D. Diana

Chantryce Elana Diehl

Raymon E. Diehl

The Dirty Dash

Vera Caren Dixon

The Dodo Restaurant

Draper Lions Club

Gaye N. and R. Michael Duffin, MD

George H. and Joan D. Earl

Steven George and Ingunn Hoff Earl

Joshua D. Echols

M. David Eckersley and Anne Milne

John S. and Evelyn B. Edwards

Sarah and Bob Ehrlich

Rolf Engen

Falcon’s Ledge

James Farmer

Fat Cats

Richard A. and Carol M. Fay

Michael S. and Eugene Feldman

Spencer P. and Barbara S. Felt

Fish Tech Outfitters

Carole E. and Bruce R. Fishburn, MD

Keith A. and Cindy Hadden Fleming

Flowrider

Foothill Oriental Rugs

Frankie Ford

Stanley and Janice T. Foutz

Bonnie O. and Joseph B. Fowler, Jr.

Arthur E. and Victoria E. Franks

Peter Q. Freed

Heidi L. and Roger C. Furlong, MD

Jay and Lynda Gamble

David Ganansky and Cindy Nordling

David P. and Sheila S. Gardner

Paul E. Garland, MD

Gastronomy, Inc.

Deanna R. Gerber

Hans G. and Martha S. Ahrens

Alcohol Servers Training of Utah LLC

Richard A. Aldous, MD

Raymond H. and Ila Jane Aldrich

Ray W. and Bonnie Lou Alvord

Anil Amoogum

Gaby Anderson

Milton M. and Dianne K. Anderson

Catherine and Barry J. Angstman

Joey Archer

Mark and Christine Archibald

Aristo’s

John W. and Diane V. Armour

AsArt

Alan C. and Karen Ashton

Pamela J. Atkinson

Leah A. Baker

Jean S. Barker

Robert R. and Laurel Barrett

Surya Bastakoti and Carmen L. Fournier

Lloyd and Nancy Beacom

Jon C. and Carol L. Beck

Beehive Bail Bonds

Patricia Ann Berg

Brian Besch

Carl M. Biehn

Black Diamond Equipment, Ltd.

Emmy S. Blechmann

Elmen D. and Monika Bloedel

Elizabeth B. and H. Allen Bloomer, MD

Blum, Inc.

Steven J. Borst

Dave D. and Cate H. Boulden

Betsy T. Bradley

Stephen K. Bradley, MD

Carolyn O. Braza

Hugh and Constance Brennan

J. Steven and Susan J. Brown

Dolores Z. Buchanan

Shirley E. and Billie N. Burke

John K. Bushnell

William L. and Sheral L. Calvin

Robin C. Campbell and Marion Rogers Riley

Canyons Resort

Robert S. and Kimberly Ann Carson

Rameshwor Chapagain

Michelle and Craig J. Chaya, MD

Todd Chikaraishi, DDS

George A. and Pauline O. Childs

Qing Chong

Don V. and Anne E. Christensen

Mary T. and Andrew B. Christensen, PhD

Thayer S. and Sue D. Christensen

The Church of Jesus Christ of Latter-day Saints Foundation

Glenn D. and Kara E. Clapp, PhD

Willa Dean Cocorinis

Richard and Susan Coe

Cole Sports

Joseph V. & Nancy C. Cook

Robert D. and Cheryl D. Cook

Drury W. Cooper, III

Michael* and Diane Cooper

Ed and Deborah A. Cooper

William and Barbara B. Cowan

Vicki Cram

Lisa Z. and David A. Crandall, MD

Rufus L. Crawford

Yue and Donnell J. Creel, PhD

Paul B. Crookston

Alan S. and Joan E. Cruickshank

Craig W. Dayhuff

Deerfield Ranch Winery

Edward R. and Terri Dejulis

Denver Eye Surgeons

Gwila C. Despain

J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2

Stephen L. and Leslie Goddard

Lawrence K. and Suzanne Goldsmith

Roxanne Googin

Shari Gowers

Robert M. and Joyce S.* Graham

Grant Farms

Neil J. and Stephanie D. Gray

Donald R. and Susan Greenberg

The Group Real Estate, LLC

Thomas L. and Victoria E.* Guinney

Doug and Kristy Gunnell

David G. and Donna Ann Hall

John R. and Andrea M. Hampshire

Barry K. Hanover and Allison R. Brunvand

Gerald and Betty Jo Hanson

Sylvia and Roger P. Harrie, MD

Joy T. Hashimoto

Barbara Ann Hathaway

Jim and Jennifer Hathorne

Rick F. and Jane R. Hays

William G. Hayward, Jr.

Jack Hegardt Masonry

John B. and Jean M. Henkels

Gary J. and Elvia I. Hennings

Ruth A. Hensel

Margaret D. and Hillard D. Hicks

Hidden Valley Country Club

David C. and Eileen Grevey Hillson

Himalayan Kitchen Restaurant

Ross and Kathy S. Hinman, DVM

Einar and Madora I. Hoff

H. Earl and Barbara C. Hoover

Edward L. Hughes and Roberta L. Anner-Hughes

Gilbert H. and Thelma P. Iker

James F. Ingold

Intermountain Harley Davidson

Edward M. and Nita Jenkins*

Martha Lewis Jennings

Jerry J. and Roslyn Jensen

Norman S. and Gail R. Jensen

Lars and Kendeyl D. Johansen

Johnie’s

Thomas P. and Wendy A. Johnson

Patty S. and Randolph L. Johnston, MD

Ryan C. and Jaime Lynn Jones

Leon L. and Judith Anne Jones

Zachary Joos, MD

Carol A. Jost

Wally Joyner

Michael J. and Dianne Jean Kane

Alan and Pam Kantrowitz

Charles and Laurel D. Kay

Kearns Lions Club

KEEN

Dennis Keller

Jean L. Kendall

Carl R. and Gillean M. Kjeldsberg

William M. and Julia J. Kleinschmidt, PhD

Rodney James Korst and Lynn Price, MD

Peter and Geraldine S. Kypreos

Polly I. Lambson

Larry G. and Dixie D. Lehman

Larry G. and Claire O. Leonard

Ralph M. and Susan M. Lewis

Links to Clinical Research LLC

Laura P. and Robert P. Liss, MD

Richard M. and Susan N. Lockwood

Los Miradores Unit Owners Association

James L. and Carol C. Macfarlane

Mercina and Nick Mamalis, MD

Mammco, LLC

Tad and Mary Mancini

Brent V. and Chris C. Manning

Michael and Andrea Manship

Franklin Marold

Julie Marple

Steven and Karen Marsden

George and Connie Marshall

William A. Marshall

Charles and Florence I. Masters

Willard Z. and Rona Lee Maughan

Les E. and Therese M. Mayes

Mayfield Lions Club

David and Laura McArthur

Sandra and Duncan K. McDonald, MD

Molly L. McFadden

Daniel J. McInerney

Scott E. McIntosh

Ms. Jeanne L. McJoynt

Philip M. and Susan L. McLaughlin

John and Emily McVey

Don and Mary Mealing

Marvin and Renee Melville

Lloyd R. and Marjorie R. Merrill

Larry H. Miller Sports & Entertainment Group

Patricia G. Millington

Nathan Miller

Aditya V. Mishra, MD

Montebello Truck Terminals

Montgomery Fur Co.

Amedee D. and Cammie Moran

John A. Moran Eye Center Optical Shop

Judith S. Moreton

Anthony W. and Mary Ann Morgan

John and Cherie Morris Family Foundation

Anna C. and Grant Morshedi, MD

Mountain Film in Telluride

Mountain Trails Foundation

Mountain View Animal Hospital

Gene Muir

J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2

Fo

cu

s 2

013

52

Fo

cu

s 2

013

53

Spencer 2010 Vision PC

Heather and Terrence Scott Spencer, MD

Squatter’s Pub Brewery

Marland L. and Rachel Stanley

Robert and Rosemary Starr

Shirley N. Stevenson

Thomas G.* and Martha G. Stockham

John R. and Helen B. Stone

William E. and Dena Stratton

Preston and M. Catherine Strazza

Charles and Kathleen Feid Sturgis

Raju Subedi

Carlton T. Sumison

Sundance Institute

Super Sonic Car Wash

Edward Harris Sweet

Geoffrey Tabin, MD

Lary J. and Judy W. Talbot

William Tanner & Susan Heath

Carolyn W. and Kim Y. Taylor, MD

Mark Taylor

Robert C. and Jacque Taylor

R. Burke Teichert

Thanksgiving Point

David B. Theobald

Mary E. Thompson

Craig Tinkham

Lilian S. Tinsley

Kris Tribe and Scott S. Hale

Jim and Candy Turnbull

Kirk A. Umphrey, CPA

Stephen C. and Kathy Ure

Paul and Kristi Ann Urry

Utah Mountain Adventures

V Chocolates

Maynard H. and Carol B. Victor

Vinto Restaurant

Albert T. Vitale, MD and Patricia A. Vitale, MD

Ron and Kris Murri

Bobby Nassir

Native Eye Wear

William H. and Christine M. Nelson

Newpark Resort and Hotel

Hanh T. Ngo

Roland C. Nickerson

Samdup Norgyal and Thupten Wangmo

Jennifer Norris, MD

Michael A. Norseth

Clay W. and Dianne R. Northrop

David E. Oberly and Karen Ehresman

Charles W. and Joan Odd

James and Sandra O’Hearn

The Olive Garden

Osprey Packs

Outdoor Utah

Eugene and Jean Overfelt

Paisley Pomegranate

Richard D. Paisner and Christie Weiner

Joseph J. and Dorothy Ann Moyle Palmer

Park City Lions Club

Karen and Matthew R. Parsons, MD

Patagonia

Gregory G. Pavich

Chase N. and Grethe B. Peterson

Elaine Peterson

Gary Peterson

Peter W. and Anne P. Peterson

Raymond R. and Judith C. Peterson

PETZL America

Piaget Designs

Marlynn Pike

Paul Z. and Lisa Dang Pilzer

Ralph W. and Maurine* Pixton

Blanche B. Prisbrey

The Pub Group

Susan J. Quaal, PhD

James W. and Brunhilda Rail

Elizabeth D. and V. Ramama Rao

Mervin J. and Verna B. Rasmussen

L. Richard and Jean C. Raybould

Debra S. and J. Scott Raymond, MD

Colleen M. Reardon

Ralph E. and Rita G. Reese

Donald G. Reid

Research to Prevent Blindness

Saeed Rezai and Christine M. Turner-Rezai

Gladys Richardson

Alvin and Helene Richer

Phil and Glenda Riesen

Manda and Robert E. Robinson, JD

Ron Rubin

Susan L. Ruebush

Melodie Rydalch

Saari Revocable Trust

John M. and Melanie A. Sacco

David E. and Lois P. Salisbury

Salt Lake Country Club

Salt Lake County Government Center

Salt Lake Marriott Downtown

Paul F. and Janice W. Sargent

Tasha Savage

Peter and Jutta Scholla

John F. Schroll

Susan B. Schulman

Michael R. Scott and Loretta G. Falvo-Scott

Sego Art and Frame

Jerry Seiner Chevrolet Employees Fund

Roger Shane

Pamela B. Sheeler

William Simkins

Albert H. Small

Quentin R. Smelzer, Jr.

Clark T. Smith

Otto F. Smith, MD

Mark E. and Vicki L. Southwick

J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2

William L. and Nancy Y. Wagner

D. Jesse and Ann T. Wagstaff

Gerald Wallace and Ruth Y. Cooke

W. Jeffrey and Mona Walters

Jana C. and Curtis R. Ward, JD

Matthew and Lynn W. Ward

Jeffrey S. Ware

Judith E.A. Warner, MD

Marta Sutton Weeks-Wulf

George P. and Adele W. Weiler

Wells Fargo

Marilyn F. Westegaard

Bart L. and Marlene G. Wheelwright

Pauline Wiessner, PhD

Don M.* and Joleen Willey

John W. Williams

Gordon R.* and Georgia A. Wilson

Jennifer Wilson and Trell Rohovit

Ted L. Wilson and Holly J. Mullen

David B. and Jeralynn T. Winder

Pamela and Robert W. Wing, MD

Wisan, Smith, Racker & Prescott

Bruce R. and Jean P. Wisan

Richard and Nancy S. Wolthius

Michael H. Yei and Jill A. Miller

Zy Restaurant

I N H O N O R O F

Those in whose honor gifts were made to the Moran Eye Center from January 1, 2012 through December 31, 2012

Captain Daniel M. Anderson, MD

Paul S. Bernstein, MD, PhD

Kim Corbin-Lewis and David R. Lewis

Julie and Alan Crandall, MD

Laverne and David Diehl

Jason Goldsmith, MD

Susan W. Hodgins

Alan E. Huish

Collin G. Jensen and Heidi J. Hunsaker

Brandon and Rebecca Jensen

Bradley Katz, MD, PhD

Bonnie and Ernie Messerly

John A. and Carole Moran

Majid Moshirfar, MD

Terry and Tiffany Parkin

Matthew R. Parsons, MD

Matthew Porter

Tami Porter

Thomas Starkovich

Michael P. Teske, MD

Albert Vitale, MD

John Waldrip

I N M E M o R y o F

Those in whose memory gifts were made to the Moran Eye Center from January 1, 2012 through December 31, 2012

Louis B. Baker

Elizabeth R. Beier

Maxine Bernhisel

Charles W. Bezyack

Eugene (Jim) Smith Bezzant

Robert Buchmiller

Thomas Callahan

Dan Changar

Dan Collings

Eloise and Kirkham V. Crabb

Helen Bell Crawford

Robert V. Despain

Clifford Benjamin Digre

Robert Duke

Donald “Don” Eyre

Edith A. Fallentine

Susan Fallentine Flatberg

Jack Forgie

Mildred Gawlicki

Ted Hallstrom

Mark Hanna

Martha Ann Dumke Healy

Margaret Hutchings

Jennie Janzen

Clara Jaques Richins Jensen

Lois E. Bleak Johnson

Tim Lynch

Thomas J. McJoynt

Kevin Craig McKenna

Fern Whicker Mortensen

Steven Nichols

Elaine Nielson

Donna Olson

Don Percival

Neuman C. Petty

Anna K. Picco and Patricia Politano

Robert A. Pirtle

Maurine Pixton

Ramona Rochford

Lynn Seely

Edward G. Shearer

Robert C. Sloan

James H. Swonson

Isabel Thomas

Effie Torrey

Elton Varner

Leslie Wansgaard and Pearl Kirk

Don Willey

William Meeks Wirthlin

*Deceased

The Moran Eye Center is very grateful for the contributions made to support our mission and goals. We have made every effort to ensure that this 2012 Donor Report is as accurate as possible. Should you find an error or wish to change your listing, please feel free to contact us at 801-585-9700.

J o H N A . M o R A N E y E C E N T E R D o N o R R E P o R T F o R 2 0 1 2

Fo

cu

s 2

013

54

Fo

cu

s 2

013

55

Appointments, Honors, and Awards

AppointmentsBalamurali K Ambati, MD, Official Utah Utes Team OphthalmologistPhD, MBA

Mary Elizabeth Hartnett, MD International Association for Research in Vision and Ophthalmology (ARVO) Program Committee for Retinal Cell Biology

Chair Elect, ARVO Ethics and Regulations in Human Research Committee Study Section for Diseases and Pathology of the Visual System

Women in Ophthalmology Audit Committee

National Research Policy Committee, American Diabetes Association

Credentials Committee, Macula Society

University of Utah Committee for Academic Promotions, Retention, and Tenure

Academic Senate Teleophthalmology Board

Wayne Imbrescia, MPH, MHSA President of University Administrators of Ophthalmology

Nick Mamalis, MD Governing Board, American Society of Cataract and Refractive Surgery

Randall J olson, MD President of the Association of University Professors of Ophthalmology April 1, 2012 – March 31, 2013; continuing to serve in the capacity of Past President until March 2014

Liliana Werner, MD, PhD Board member, Institutional Review Board, University of Utah

Honors and AwardsWolfgang B Baehr, PhD Association for Research in Vision and Ophthalmology’s highest research honor,

a $100,000 prize from the ALCON Research Institute for research that is likely to “expand the frontiers of vision sciences throughout the world”

Kathleen B Digre, MD Rosenblatt Prize for Excellence, the University of Utah’s highest faculty honor

Martha Hughes Cannon Award for contributions to women’s health in the state of Utah, Utah Department of Health

R Michael Duffin, MD Recognition for Humanitarian Service from FUDEM, a woman’s humanitarian service organization dedicated to providing eye care to the needy, in El Salvador at their 20th Anniversary Celebration, San Salvador

yingbin Fu, PhD National Eye Institute Travel Award, XVth International Retinal Degeneration Symposium, Bad Gögging, Bavaria, Germany

James Gilman, CRA, FoPS Honorable Mention for “Ravenous Retinopathy” and Second Place for an “Iris Tumor” at the Ophthalmic Photographers’ Society (OPS) Scientific Exhibit at the American Academy of Ophthalmology Annual meeting

Outstanding Contribution Award for five years of teaching from the Joint Commission on Allied Health Personnel in Ophthalmology

Gregory S Hageman, PhD Lighthouse International Madame Georgette Pisart Vision Award for the “most extraordinary advance in the field with work of an enduring nature that has inspired others”

Prix de la Recherche, Macula of Paris

J o H N A . M o R A N E y E C E N T E R

2012-2013Senior Scientific Investigator Award, Research to Prevent Blindness

Harold Gifford Jr, MD, Lecture, Stanley M Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska

Congressional Briefing Featured Speaker, AEVR Sponsored International Age-related Macular Degeneration Week 2012, 20 September, Washington DCAge-related Macular Degeneration Week 2012, 20 September, Washington DCAge-related Macular Degeneration Week

Roger P Harrie, MD Annual Service Award from the Salt Lake Valley Youth Detention Center for a glasses project in which he checks the eyes of youth in detention and donates glasses to those who need them

Mary Elizabeth Hartnett, MD Representative nominated by Retina Society for Practicing Ophthalmologist Curriculum

Robert o Hoffman, MD Lewis Peterson Award at Primary Children’s Medical Center, Principle Investigator-eROP, Utah Study Center

Bryan W Jones, PhD First Place, International Science and Engineering Visualization Challenge sponsored by the journal Science and the National Science Foundation

Julia Kleinschmidt, PhD, LCSW Awarded Emeritus Professorship, the University of Utah, 2012

Nick Mamalis, MD Best Poster Award – ASCRS/ESCRS, 2012: Survey on Foldable IOLs Requiring Explanation or Secondary Intervention: 2011 Update. American Academy of Ophthalmology annual meeting, Chicago , Il

Robert E Marc, PhD University of Utah Distinguished Professorship

Mark D Mifflin, MD Residents’ Outstanding Faculty Member Award, 2012

Richard A Normann, PhD Presented with a Festchrift, “a volume of learned articles or essays by colleagues and admirers, serving as a tribute or memorial especially to a scholar,” honoring his 70th birthday, February 8, 2013

Randall J olson, MD Binkhorst Medal of Honor for “an individual as making significant contributions to the science and practice of ophthalmology and establishes that person among the world’s most prominent ophthalmologists,” American Society of Cataract and Refractive Surgery

Binkhorst Award for American Society of Cataract and Refractive Surgery, 2012

Monica Vetter, PhD Innovative Ophthalmic Research Award for Research to Prevent Blindness;Chair, 1 R13 EY020680 Visual System Development Gordon Research Conference, 2010 Visual System Development

Liliana Werner, MD, PhD Best-Paper-of-Session Award, Session 3-N IL Intraocular Surgery Complications: “Pathological Assessment of Complications with Asymmetric or Sulcus Fixation of Square-edged Hydrophobic Acrylic IOLs,” the Annual Meeting of the American Society of Cataract and Refractive Surgery, Chicago, Illinois

First Prize, EDUCATIONAL category for The Art of the Pre-chopping: Analyses from the Miyake-Apple Perspective, at the video festival of the XII International Congress of Cataract and Refractive Surgery Video Festival, São Paulo, Brazil

Afonso Fatorelli Medal and Lecture, XII International Congress of Cataract and Refractive Surgery, São Paulo, Brazil

The Mamalis/Werner Lab received a donation from Alcon Laboratories in the value of $50,000 dollars to support analyses of light scattering and light transmission of explanted intraocular lenses. Alcon also provided two pieces of equipment in the value of $30,000, which are essential for these analyses: an anterior segment analyzer (EAS-1000 Scheimpflug camera, Nidek) and a UV-Vis spectrophotometer (Perkin-Elmer Inc)

Paul Zimmerman, MD The family of the late Dr. Zimmerman, former ophthalmologist and educator at the Moran Eye Center, along with the Utah Lions Eye Bank and many other donors, made possible the purchase of a state-of-the-art eye surgery simulator (EYESi) to enhance education and training programs. Dr. Zimmerman, the Utah Lions Eye Bank, and other donors who helped purchase the simulator were honored at an event held at Moran Eye Center, 18 September, 2012

J o H N A . M o R A N E y E C E N T E R

Fo

cu

s 2

013

56

Fo

cu

s 2

013

57

Balamurali K Ambati, MD, PhD, MBA2008-Present Section Editor, American Academy of Ophthalmology, Basic & Clinical Science course in ophthalmology

Ad Hoc Member, National Eye Institute, Special Emphasis Panel

Alessandra Angelucci, MD, PhD2008-Present Review Editor, Frontiers in Neuroanatomy

2007-Present Member, Editorial Board for Visual Neuroscience

Review Editor, Frontiers in Systems Neuroscience

2007-Present Member, American Physiological Society, USA

2002-Present Committee Member, Departmental Distinguished Speaker Seminar Series, Department of Ophthalmology, University of Utah

1997-Present Member, British Neuroscience Association, UK

1994-Present Member, Society for Neuroscience, USA

1990-Present Member, Italian Medical Doctors Association, Italy

Wolfgang B Baehr, PhD 2012 Organizer, the 14th Annual Vision Research Conference, Board of Vision Research; a two-day meeting on Retinal Ciliopathies: From Genes to Mechanisms and Treatment, preceded ARVO, Ft. Lauderdale

Organizer, the five-day XX Biennial Meeting of the International Society for Eye Research, Retinal Neuroscience, Berlin, Germany

Editor, Vision Research, volume 53, (2012). Special Edition of the 14th Biannual Vision Research Conference on “Retina Ciliopathies: From Genes to Mechanisms and Treatment”

2004-Present Senior Editor, Vision Research, Elsevier Science, San Diego, CA

Paul S Bernstein, MD, PhD 2012-Present Member, Board of Trustees, Association for Research in Vision and Ophthalmology

2011-Present Organizer, the 17th International Symposium on Carotenoids, Park City, Utah

2008-Present Mary Boesche Endowed Professor of Ophthalmology and Visual Sciences

2008-2011 Committee Member, Biochemistry Program, Association for Research in Vision and ophthalmology

2006-Present Elected Member, America’s Best Doctors

2005-Present Medical Advisor, Journal of Ophthalmic Photography, University of Utah World class U award

Member, Scientific Advisory Board, International Symposium on Ophthalmic Pharmacology and Therapeutics

Margaret DeAngelis, PhD 2012-Present Member, Executive Committee, International Consortium for Refractive Error and Myopia, sponsored by NEI/NIH

Member, Editorial Board, International Scholarly Research Network Genetics

Member, International Consortium for Refractive Error and Myopia

Member, Age-related Macular Degeneration Gene Consortium

J o H N A . M o R A N E y E C E N T E R

2012Industry Leadership and ServiceThis is a partial list of Moran Industry Leadership and Service for 2012

2012 Member, National Institute of Health ZRG1 F05-R Fellowship: Cell Biology, Development, and Bioengineering Study Section

Member, Macular Degeneration Foundation, Australia Research Grants Program, Peer Review Panel

Session Co-chair, “Nuclear Receptors and their Role in the Retina and in AMD,” Biennial Meeting of the International Society for Eye Research, Berlin, Germany

Chairperson, Rapid Fire Presentations: 9th Alumni & Research Day, Centre for Vision and Vascular Science and Royal Hospitals, Queens University, Belfast, Ireland

Judge, Post-doctoral Fellows Poster Sessions: 9th Alumni & Research Day, Centre for Vision and Vascular Science and Royal Hospitals, Queens University, Belfast, Ireland

2011-Present Member, Senior Executive Committee/Steering Committee, Age-related Macular Degeneration Gene Consortium, sponsored by the NEI/NIH

2010-Present Member, National Institutes of Health, Research Peer Review Panel, Edinburgh, Scotland, United Kingdom

Member, Australia Macular Degeneration Foundation, Research Peer Review Panel

2008-Present Member, Guide Dogs for the Blind, Research Peer Review Panel, United Kingdom

Kathleen B Digre, MD 2010-Present Member, Achievement Rewards for College Scientists

2007-Present Visiting Professor, American Academy of Ophthalmology, Neuro-Ophthalmology/Orbit, Differential Diagnosis of Headache and Eye Pain

2004-Present Chairman, Board of Directors, North American Neuro-Ophthalmologic Society

Chair, American Headache Society Publications Committee

2003-Present Member, American Neurological Association Membership Committee

Member, International Genetic Epidemiology Society

2002-Present Member, American Headache Society Review Board

2001-Present Representative, American Neurological Association, to One-Voice (aka American Brain Coalition)

Fellow, American Heart Association Stroke Council

1999-Present Member, American Headache Society Grant and Awards Committee

Member, Association for Research in Vision and Ophthalmology

1998-Present Board of Directors, Member, North American Neuro-Ophthalmology Society

1995-Present Member, Editorial Board, Journal of Neuro-Ophthalmology

R Michael Duffin, MD 2012 Member of the Vision Advisory Committee of the Humanitarian Department of The Church of Jesus Christ of Latter-day Saints, with responsibilities to assist in developing humanitarian vision care projects for the needy in Latin America

2008-Present Member, Interview Sub-committee of the Admissions Committee of the University of Utah School of medicine

Sabine Fuhrmann, PhD 2011-Present Academic Senate

2012 Member, Molecular Biology Graduate Program Admission Committee

2012 Internal Reviewer, Graduate Council Review for the Department of Pharmacology and toxicology toxicology t

2012 Member, Funding Incentive Seed Grant Program

2004-Present Member, Editorial Board, Developmental Dynamics

Member, Society for Neuroscience, Association for Research and Vision in Ophthalmology, Society for Developmental Biology, Research to Prevent Blindness

J o H N A . M o R A N E y E C E N T E R

Fo

cu

s 2

013

58

Fo

cu

s 2

013

59

Gregory S Hageman, PhD 2012 Scientific Founder, Voyant Biotherapeutics LLC, Salt Lake City, UT

Member, National Eye Institute, Age-related Eye Disease Study 2 Advisory Group

Member, NIH ZEY1 VSN Study Section

Member, National Eye Institute Age-related Macular Degeneration Gene Consortium

2012-Present Member, Sequenom, Inc., Ophthalmology Clinical Advisory Board

2011-Present Advisor, Gerson Lehrman Group

Member, Foundation Fighting Blindness Scientific Advisory Board

2010-Present Member, Macular Degeneration Foundation Australia Scientific Committee

Member, Advisory Board, ViroPharma Incorporated

Advisor, Apeliotus Technologies Inc.

Member, American Society for Cell Biology

Member, American Society for Matrix Biology

Member, Association for Research in Vision and Ophthalmology

Member, Central States Microscopy & Microanalysis Society

Member, Electron Microscopy Society of America

Member, International Complement Society

Member, International Society for Eye Research

Member, International Society for Matrix Biology

Member, International Society for Ocular Cell Biology

Member, Macula Society

Member, Phi Beta Kappa

Member, Schepens International Society

Member, Sigma Xi Scientific Research Society

Member, Society for Neuroscience

2009-Present Member, AMD Alliance International Board of Directors

Member, Executive Committee, Arnold and Mabel Beckman Initiative for Macular Research

Member, Edward N & Della L Thome Memorial Foundation Scientific Review Committee

Member, Alcon Research Institute

Advisor, Allergan Pharmaceuticals, Irvine, California

Mary Elizabeth Hartnett, MD 2012 Committee Member Elect, ARVO Program for Retinal Cell Biology

Chair Elect, ARVO Ethics Committee

Member, National Eye Institute Study Section for Diseases and Pathology of the Visual System

Member Elect, Board of Directors, Women in Ophthalmology

Member, National Research Policy Committee, the American Diabetes Association

Member, Credentials Committee, the Macula Society

Member, Committee for Academic Promotions, Retention, and Tenure; Academic Senate Teleophthalmology Board, University of Utah

Organizer and Host, International Association for Pediatric Retinal Surgeons Meeting, Park City, Utah

2012-Present Editor, American Academy of Pediatric Ophthalmology and Strabismus

2011-Present Editor, Molecular Vision Scientific Review

2009-Present Member, Honorary Editorial Board, Patient Related Outcome Measures (Dove Press)

2009-Present Member, Honorary Editorial Board, Eye and Brain

Member, Editorial Board, Clinical Ophthalmology

J o H N A . M o R A N E y E C E N T E R

Bryan W Jones, PhD 2002-Present Editor/Webmaster, Webvision http://webvision.med.utah.edu

1992-Present Member, American Association for the Advancement of Science

1999-Present Member, Association for Research in Vision and Ophthalmology

2004-Present Member, Medical School Admissions Committee

Bradley J Katz, MD, PhD 2011-Present Member, Self-assessment Committee, Item Review Subcommittee, American Academy of Ophthalmology

Primary Investigator, Technology Commercialization Project Grant, “Development of Thin Films to Treat Photophobia and Migraine,” University of Utah Technology Commercialization Office

2009-Present Primary Site Investigator, Phase I Open Label, Dose Escalating Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Patients with Optic Nerve Atrophy (Stratum I) and Acute Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) (Stratum II), QUARK Pharmaceuticals, Fremont, California

Member, Committee on Aging, American Academy of Ophthalmology

David Krizaj, PhD 2012 Moderator, Association for Research in Vision and Ophthalmology, Membrane Physiology,

and Signal Transduction Poster Session

Member, Special Interest Group, Association for Research in Vision and Ophthalmology

Co-organizer and Moderator, RGC Death in Optic Neuropathies and Retinal Ischemia

Session Co-moderator, “TRP Channels in Eye Research,” International Society for Eye Research Conference, Berlin

2012-Present Member, Editorial Board, Center for Translational Medicine, University of Utah

2011-Present Member, Editorial Board, International Journal of Physiology, Pathophysiology and Pharmacology

2010-Present Member, Editorial Board, Society for Neuroscience Intermountain Chapter, Open Access Animal Physiology

2009-Present Member, American Physiological Society

Member, Scientific Inquires in Qualia Interdisciplinary Faculty Research Interest Group under auspices of Tanner Humanities Center

2007-Present Member, American Association for the Advancement of Science

2006-Present Member, International Society for Eye Research

2004-Present Member, Sinapsa (Slovenian Association for Neuroscience)

1996-Present Member, Association for Research in Vision and Ophthalmology

1992-Present Member, Society for Neuroscience

Edward M Levine, PhD2004-Present Member, Editorial Board, Developmental Dynamics

Nick Mamalis, MD2012 Moderator, Cataract Symposium, American Society of Cataract and Refractive Surgery,

Chicago, Illinois

2007-Present Editor, Journal of Cataract and Refractive Surgery

Member, Executive Committee, American Society of Cataract and Refractive Surgery

1998-Present Editorial Board, Review of Ophthalmology

1997-Present Member, American Society of Cataract and Refractive Surgery Cataract Clinical Committee

1989-Present Member, Board of Directors, National Society to Prevent Blindness: Utah Affiliate

1988-Present Volunteer, Research to Prevent Blindness Ophthalmological Associate

J o H N A . M o R A N E y E C E N T E R

Fo

cu

s 2

013

60

Fo

cu

s 2

013

61

Robert E Marc, PhD 2012 Member, Editorial Board, Journal of Comparative Neurology, Society for Neuroscience

Member, Association for Research in Vision and Ophthalmology

Member, American Association for the Advancement of Science

Member, Optical Society of America

Majid Moshirfar, MD 2012-Present Member, Editorial Board, Oman Journal of Ophthalmology

Member, Editorial Board, Journal of Cataract and Refractive Surgeons Consultation Section

2011-Present Member, Editorial Board, Scientific World Journal

2009-Present Member, Editorial Board, International Advisory Board, Middle East African Journal of Ophthalmology

Richard A Normann, PhD Host, 40th Neural Interfaces Conference, Salt Lake City, Utah

Randall J olson, MD 2012 Executive Editor, American Journal of Ophthalmology

Editorial Board, Ophthalmologica

Bhupendra C K Patel, MD, FRCS, FRC 2007-Present Chief Section Editor, Plastic Surgery, British Journal of Ophthalmology

2006-Present Chief Section Editor, Plastic Surgery, EYE

2005-Present Chief Co-editor, ORBIT

2003-Present Member, Editorial Board, Evidence Based Eye Care

2002-Present Editor, USA ORBIT

2000-Present Member, Editorial Board, Aesthetique

1999-Present Member, Editorial Board, Journal of Cranio-Maxillofacial Trauma

1996-Present Member, Medical Advisory Board, American Society of Ocularists

1991-Present Member, Editorial Board, Abstracts from the Literature for Ophthalmic, Plastic, and Reconstructive Surgery

Geoffrey Tabin, MD 2006-Present Editor, Stedman’s Medical Dictionary

Monica Vetter, PhD 2011-present Member, Scientific Advisory Board, “Catalyst for a Cure 2,” Glaucoma Research Foundation

Albert T Vitale, MD 2011-Present Member, University of California, Los Angeles, UCLA Center for the Health Sciences, International Workshop on Uveitis in Children, Jules Stein Eye Institute

2009-Present Member, American Uveitis Society, Standardization of Uveitis Nomenclature (SUN) Working Group

2009-Present Member, American Uveitis Society Executive Committee, Secretary for Internal Affairs

2006-Present Member, Editorial Board, Editorial and Writing Committee for Practicing Ophthalmologists Committee, American Academy of Ophthalmology

Editor, American Academy of Ophthalmology Basic Science Course

Editor, Intraocular Inflammation, Uveitis, and Tumors, Focal Points

2005-Present Contributing Editor and Writing Committee Member, “Intraocular Inflammation and Uveitis, BCSC 9, Basic Science Course,” American Academy Ophthalmology

Section Editor, Uveitis and Intraocular Tumors, Focal Points, American Academy of Ophthalmology

J o H N A . M o R A N E y E C E N T E R

Judith E A Warner, MD 2004-Present Member, Editorial Board, Neuro-Ophthalmology

Liliana Werner, MD, PhD 2012 Chief Judge, Annual Video Festival, American Society of Cataract and Refractive

Surgery

Member, Scientific Advisory Board, Powervision Inc.

2012-present Board Member, Institutional Review Board, University of Utah 2012

2011-present Chair, Continuing Medical Education Advisory Committee, American Society of Cataract and Refractive Surgery 2010-Present

2010-present Chair, Sequenom, Inc., Clinical Advisory Board

2009-present Member of the Scientific Advisory Board of Powervision Inc., USA

2009-present Member, American Academy of Ophthalmology Ophthalmic News & Education Network

2004-Present Member, Editorial Board, Journal of Cataract & Refractive Surgery

2004-Present Member, Editorial Board, EyeWorld Magazine

2003-present Member, Continuing Medical Education Advisory Committee, American Society of Cataract and Refractive Surgery

Barbara M Wirostko, MD2012 Member, Advisory Board and Chairperson/ Moderator, 4th Ocular Diseases and Drug Discovery Conference, Las Vegas, Nevada

2011-Present Chief Medical Officer Retained Consultant, Altheos, Inc.

Executive Team Member, Lead Clinical Development Program & Glaucoma Strategy, Novel Rho Kinase Inhibitor, Currently in Phase 2

Ophthalmology Consultant and Member, Medical Advisory Board, Premier Research LTD., Wokingham, United Kingdom; expert Advisor, Ophthalmology Drug Development Clinical Research Protocols and Strategy

Chief Medical Officer and Strategic Advisory Board Member, SKS Biotech Incubator Investigating Novel Delivery Methods for Ophthalmic Diseases: AMD & Glaucoma

Member/Advisor, Entrepreneurial Faculty Scholars, Entrepreneurial Opportunities and Clinical Research, University of Utah

Member, Scientific Advisory Committee for Glaucoma Research Foundation, San Francisco, California

2011 Advisory Board Member, Chairperson, Moderator, 3rd Ocular Diseases & Drug Discovery Conference, Boston, Massachusetts

2010-Present Member, California Institute for Regenerative Medicine Scientific and Medical Research Grants Review Working Group, Editorial Board, Acta Ophthalmologica

2009-Present America Top Ophthalmologist, Journal of Consumer Research

2007-Present Associate Editor and Peer Reviewer, Acta Ophthalmologica

Jun yang, PhD 2012 Member, Scientific Review Committee, Fight for Sight, New York, New York

J o H N A . M o R A N E y E C E N T E R

Fo

cu

s 2

013

62

Fo

cu

s 2

013

63

RETINA Title: Follow-up Evaluation of Participants from a Prior Study of Implants of Encapsulated Human NTC-201 Cells Releasing Ciliary Neurotrophic Factor (CNTF) for Atrophic Macular Degeneration

Sponsor: Lowy Research InstitutePrincipal Investigator: Paul S Bernstein, MD, PhD

Title: Age-related Eye Disease Study 2 (AREDS2): A Multi-center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 Long-Chain Polyunsaturated Fatty Acids (Docosahexaenoic Acid [DHA] and Eicosapentaenoic Acid [EPA]) in Age-related Macular Degeneration

Sponsor: NIH/NEIPrincipal Investigator: Paul S Bernstein, MD, PhD

Title: Home-vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device

Sponsor: Notal Vision, Ltd. Principal Investigator: Paul S Bernstein, MD, PhD

Title: Genetics Protocol of Macular Telangiectasia Type 2: The MacTel Study

Sponsor: Lowy Research Foundation Principal Investigator: Paul S Bernstein, MD, PhD

Title: Utah Center for the Collaborative Study of the Role of the Macular Pigment Carotenoids in the Pathogenesis and Treatment of MacTel

Sponsor: Lowy Research Institute Principal Investigator: Paul S Bernstein, MD, PhD

Title: A Phase 2, Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) Given in Combination with LUCENTIS® in Subjects with Neovascular Age-related Macular Degeneration

Sponsor: Ophthotech, Inc.Principal Investigator: Paul S Bernstein, MD, PhD

Title: Raman Measurement of Macular Carotenoid Pigments in the Human Retina

Sponsor: NIH/NEIPrincipal Investigator: Paul S Bernstein, MD, PhD

Title: Macular Pigment Imaging in Infants Using the RetCam®

Sponsor: Abbott Laboratories, Inc. Principal Investigator: Paul S Bernstein, MD, PhD

Title: A Phase II Multiple Site, Randomized, Placebo-controlled Trial of Oral Valproic Acid for Retinitis Pigmentosa

Sponsor: National Neurovision Research Institute Principal Investigator: Paul S Bernstein, MD, PhD

Title: National Ophthalmic Genotyping and Phenotyping Network, Stage 1 — Creation of DNA Repository for Inherited Ophthalmic Diseases (eyeGENE)

Sponsor: NIH/NEI Principal Investigator: Paul S Bernstein, MD, PhD

Title: Phase 2 Multicenter, Randomized Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of GSK933776 in Adult Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration

Sponsor: GlaxoSmithKline Principal Investigator: Paul S Bernstein, MD, PhD

Title: Prospective Multicenter Post-approval Study of VisionCare’s Implantable Miniature Telescope in Patients with Severe to Profound Central Vision Impairment Associated with End-stage Age-related Macular Degeneration

Sponsor: VisionCare Ophthalmic Technologies Principal Investigator: Majid Moshirfar, MD

Title: A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab as Maintenance Therapy in Subjects Requiring High-dose Corticosteroids for Active Non-infec-tious Intermediate-, Posterior-, or Pan-uveitis

Sponsor: Abbott Laboratories, Inc. Principal Investigator: Albert T Vitale, MD

Title: A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Inactive Non-infectious Intermediate-, Posterior-, or Pan-uveitis

Sponsor: Abbott Laboratories, Inc. Principal Investigator: Albert T Vitale, MD

Title: A Multicenter Open-label Study of the Long-term Safety and Efficacy of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects with Non-infectious Intermediate-, Posterior-, or Pan-uveitis Incorporating Amendment 1

Sponsor: Abbott Laboratories, Inc. Principal Investigator: Albert T Vitale, MD

Title: Long-term Followup of Patients Participating in the Multicenter Uveitis Steroid Treatment (MUST) Trial

Sponsor: NIH/NEI Principal Investigator: Albert T Vitale, MD

CATARACT AND GLAUCoMA Title: A Prospcetive Multicenter Clinical Study to Evaluate the Saftey and Effectiveness of the Synchrony® Dual Optic Intraocular Lens in Patients Undergoing Cataract Extraction

Sponsor: Visiogen, Inc.Principal Investigator: Alan S Crandall, MD

Title: A Study of Phenylephrine HCl’s and Ketorolac Tromethamine’s Ability, Alone and in Combination, to Maintain Mydriasis and Relieve Pain and Inflammation in Subjects Undergoing Unilateral Cataract Extraction with Lens Replacement (CELR)

Sponsor: Omeros CorporationPrincipal Investigator: Alan S Crandall, MD

Title: Communication about Glaucoma and Patient Outcomes

Sponsor: NIHPrincipal Investigator: Jason Goldsmith, MD

CORNEA Title: Cornea Donor Study

Sponsor: JAEB Center for Health Research/NEIPrincipal Investigator: Mark D Mifflin, MD

Title: Effect of Corneal Graft Preservation Time on Long-term Graft Success Study (CPTS)

Sponsor: NIH/NEIPrincipal Investigator: Mark D Mifflin, MD

NEURo-oPHTHALMoLoGy Title: Case-crossover Study of PDE5 Inhibitor Exposure as a Potential Trigger Factor for Acute NAION

Sponsor: Pfizer, Inc. Principal Investigator: Kathleen B Digre, MD

Currently, more than 50 clinical research trials are being carried out at the Moran Eye Center

C L I N I C A L T R I A L STitle: A Mulitcenter, Double-blind, Randomized, Placebo-controlled Study of Weight-reduction and/or Low-sodium Diet Plus Acetazol-amide vs Diet Plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss

Sponsor: NIH/NEI Principal Investigator: Kathleen B Digre, MD

Title: Phase I Open-label, Dose-escalating Trial of QPI-1007 Delivered by Intravitreal Injection to Patients with Optic Nerve Atrophy and Acute Non-arteritic Anterior Ischemic Optic Neuropathy

Sponsor: Quark Pharmaceuticals, Inc. Principal Investigator: Bradley J Katz, MD, PhD

Title: Predictive Value of Optic Nerve MRI Measurements at Onset of Optic Neuritis for Two-year MS Outcomes

Sponsor: Cummings FoundationPrincipal Investigator: Bradley J Katz, MD, PhD

Title: Thin-film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients with Migraine

Sponsor: Axon OpticsPrincipal Investigator: Bradley J Katz, MD, PhD

PEDIATRIC oPHTHALMoLoGy Title: Telemedicine Approaches to Evaluating Acute-phase ROP (The e-ROP Study)

Sponsor: NIH/NEI Principal Investigator: Robert O Hoffman, MD

Title: Postnatal Growth and Retinopathy of Prematurity Model Development Study (G-ROP)

Sponsor: NIH/NEI Principal Investigator: Robert O Hoffman, MD

Title: Ambylopia Treatment Study (ATS)15: Increasing Patching for Ambylopia

Sponsor: JAEB Center for Health Research/NIHPrincipal Investigator: Marielle Young, MD

Title: Pediatric Cataract Surgery Outcomes Registry

Sponsor: Jaeb Center for Health Research/NIHPrincipal Investigator: Marielle Young, MD

INVESTIGAToR-SPoNSoRED CLINICAL RESEARCH PRoJECTS Title: Collagenase Assisted Deep Anterior Lamellar Keratoplasty

Principal Investigator: Balamurali K Ambati, MD, PhD, MBA

Title: Topical Clinical Interventions Against Stargardt Macular Dystrophy: DHA Supplementation in Patients with STGD3

Principal Investigator: Paul S Bernstein, MD, PhD

Title: Effects of Maternal Nutrition and Intrauterine Growth Restric-tion on Infant Carotenoid Status

Principal Investigator: Paul S Bernstein, MD, PhD

Title: IIH Without Papilledema Exists

Principal Investigator: Kathleen B Digre, MD

Title: Evaluation of Optic Neuropathies with Imaging

Principal Investigator: Kathleen B Digre, MD

Title: Assessment of Photophobia in Moran Eye Center Patients

Principal Investigator: Kathleen B Digre, MD

Title: Genetic Associations in Preterm Infants at Risk of Retinopathy of Prematurity

Principal Investigator: Mary Elizabeth Hartnett, MD

Title: Genetics of Pediatric Retinal Disorders

Principal Investigator: Mary Elizabeth Hartnett, MD

Title: Preeclampsia and Retinopathy of Prematurity

Principal Investigator: Mary Elizabeth Hartnett, MD

Title: Retrospective Analysis of Neurofibromatosis Type 1-associated Optic Glioma Outcome after Treatment

Principal Investigator: Robert O Hoffman, MD

Title: Measurement of Critical Flicker Fusion Frequency

Principal Investigator: Bradley J Katz, MD, PhD

Title: Proteomics and Genomics of Giant Cell Arteritis

Principal Investigator: Bradley J Katz, MD, PhD

Title: Genomic Analysis of Non-arteritic Anterior Ischemic Optic Neuropathy

Principal Investigator: Bradley J Katz, MD, PhD

Title: Optic Nerve Drusen: Clinical Characterization and Genetic Mapping

Principal Investigator: Bradley J Katz, MD, PhD

Title: Treatment of Giant Cell Arteritis with Antibiotics

Principal Investigator: Bradley J Katz, MD, PhD

Title: Screening Device for Diseases of the Optic Nerve

Principal Investigator: Bradley J Katz, MD, PhD

Title: Retrospective Study of Descement’s Stripping Automated Endothelial Keratoplasty Outcomes

Principal Investigator: Mark D Mifflin, MD

Title: Topical Proparacaine vs Tetracaine in Photorefractive Keratectomy (PRK)

Principal Investigator: Majid Moshirfar, MD

Title: Topical Proparacaine vs Tetracaine in Laser Assisted in Situ Keratomileusis (LASIK)

Principal Investigator: Majid Moshirfar, MD

Title: Biomechanical Changes in the Cornea after Laser Assisted in situ Keratomileusis (LASIK) and Photorefractive Keratectomy (PRK)

Principal Investigator: Majid Moshirfar, MD

Title: Impact of AcrySof Glistenings on Visual Quality

Principal Investigator: Randall J Olson, MD

Title: Refractive Index and Pseudophakic Dysphotopsia

Principal Investigator: Randall J Olson, MD

Title: Quality of Life Assessment in an Indigent Population Following Cataract Surgery

Principal Investigator: Jeff Pettey, MD

Title: Experience in an Ophthalmology Clinic for Homeless Patients

Principal Investigator: Brian Stagg, MD

Title: Efficacy of Pars Plana Vitrectomy and Sub-retinal Tissue Plasminogen Inhibitor for the Treatment of Sub-macular Hemorrhage

Principal Investigator: Michael P Teske, MD

Title: Non-interventional Cross-sectional Observational Study Assessing Various Novel Vascular and Diagnostic Parameters and their Relationship to Glaucoma

Principal Investigator: Barbara M Wirostko, MD

Fo

cu

s 2

013

64

Fo

cu

s 2

013

65

Balamurali K Ambati, MD, PhD, MBA06/13/2012 Patent Pending: “Nitinol Ring-Capsulotome,” U-5400.

11/29/2012 Released to Inventor: “The Poodle-Cat,” U-5510.

12/05/2012 Patent Pending: “Raver2 as Controller of sFlt-1 and Vascular Demarcations,” U-5512.

Margaret DeAngelis, PhD7/31/2012 Patent: “Methods for Detecting Neovascular Age-related Macular Degeneration,” US8232056.Patent filed as a result of association studies performed in the DeAngelis laboratory that linked genetic variants to risk of age-related macular degeneration. US Patent Application No. 13/115,912.

Gregory S Hageman, PhD; yingbin Fu, PhD9/2012 Patent: “Methods of Diagnosing and Treating Vascular Associated Maculopathy and Symptoms Thereof.” University of Utah Research Foundation, WO 2012/125872.

Patents Pending: “Assessing Susceptibility to Vascular Disorders (ParAllele).” Washington, DC. Patent and Trademark Office.

“Binding of Complement Factor H to C-Reactive Protein (CFH-CRP Binding).” Washington, DC. Patent and Trademark Office.

“Biomarkers Associated With Age-related Macu-lar Degeneration (DIGE & MALDI Biomarkers).” Washington, DC. Patent and Trademark Office.

“Diagnostics and Therapeutics for Arterial Wall Disruptive Disorders (AMD to AAA).” Washington, DC. Patent and Trademark Office.

“Genes and Polymorphisms Associated with AMD (ParAllele).” Washington, DC. Patent and Trademark Office.

“Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration (CFHR1/R3 Deletion).” Washington, DC. Patent and Trademark Office.

“Predicting AMD with SNPs Within or Near C2, Factor B, PLEKHA1, HTRA1, PRELP, or LOC387715 (ParAllele).” Washington, DC. Patent and Trademark Office.

“RCA Locus Analysis to Assess Susceptibility to AMD and MPGNII.” Washington, DC. Patent and Trademark Office.

“Variants In Complement Regulatory Genes Predict Age-related Macular Degeneration (CFB/C2 Diagnostics).” Allikmets RL, Hageman GS, Dean MC, Gold AM. Washington, DC. Patent and Trademark Office.

Bryan W Jones, PhD; Robert E Marc, PhD2012Patent Pending: “Oncological Application of Computational Molecular Phenotyping.”

Bradley J Katz, MD, PhD2012Patent Pending: “Methods, Systems, and Apparatus for Reducing the Frequency and/or Severity of Photophobic Responses or for Modulating Circadian Cycles.” Founder and CEO of Axon Optics, www.axonoptics.com

Dr. Bradley J Katz, MD, PhD, joined with Tecport Optics to develop a ground-breaking optical interference filter coating process for plastic spectacle lenses. The process blocks the specific wavelengths of light that have been implicated as the cause of photophobic symptoms, particularly those associ-ated with triggering and exacerbating debilitating migraine headaches. The University of Utah has registered the existing proprietary property.

David Krizaj, PhD 2012Salcantay Vision Solutions, LLC CEO

2012Asha Vision, LLC, Founder and CEO

Technology Commercialization and Intellectual Property/PatentsTechnology Commercialization and Intellectual Property/PatentsTechnology Commercialization and

J o H N A . M o R A N E y E C E N T E R

2012-2013Patents, Patents Pending, Industry & Technology, Technological, and Other Scientific Innovations

“Saving Sight by Curing Glaucoma.” Dr. David Krizaj, PhD, and Asha Vision received a Technology Commercialization and Innovation Program (TCIP) grant from the State of Utah.

2012Center for Translational Medicine (CTM), University of Utah, member.

5/10/2012 Patent Pending: “Role of TRPV4 Antagonists in Ocular Disease.” Docket No. 00846-U5301.PROV. D Krizaj, DA Ryskamp, P Barabas. Inventor of a novel method for treatment of glau-coma and other ocular diseases associated with abnormal mechanical environment within the eye. the method has been validated in animal models and has the potential for a wide impact on clinical care, as there are currently no treat-ments that regulate intraocular pressure and protect retinal ganglion neurons in glaucoma.

10/16/2012 Patent Pending: “Mechanosensory Channel Antagonists in Glaucomatous Neuroprotection,” D 00846-US01.Krizaj, DA Ryskamp, P Barabas.

Richard A Normann, PhD2012 Richard A Normann, PhD, performed the first human implant of Utah electrode arrays in severed nerves of an upper limb amputee (project supported by Defense Advanced Research Projects Agency). The project sets the stage for work in blind human volunteers.

Randall J olson, MD2012 Patent Submitted: “A Vision Correction System to Minimize Intraocular Lens Rotation.”

Patents Pending: “A Vision Correction System,” patent 5087

Hypodermic Needle System and Method to Reduce Infection.” patent 4826

Liliana Werner MD, PhD1996-present “Procédé de revêtement de matériaux et produits ainsi obtenus. Téflon AF pour implant intraoculaire.”Legeais JM, Legeay G, Werner L, renard G. French patent number FR 9604267, registered on April 4th, 1996, Paris.

Barbara M Wirostko, MD2011-presentBarbara M Wirostko, MD, is co-founder and Chief Scientific Officer of Jade Therapeutics, LLC Drug Development Company focusing on developing sustained delivery drugs and prod-ucts in ophthalmic areas of high unmet need utilizing a novel crosslinked hyaluronic acid biodegradable polymer.

4/2012; 9/2012 Jade Therapeutics is the recipient of two prestigious entrepre-neurial grants: “Technology Commercialization and Innovation Program” (TCIP) grants through USTAR, $40,000 each.

8/2012–2/2013The TCIP (formerly “Centers of Excellence”) is a state-funded grant and mentoring program originally developed by the Utah Legislature in 1986 to help accelerate the process of taking cutting-edge technologies developed at Utah’s colleges and universities to market. PI: Barbara M Wirostko, MD, 10 percent effort.

2012US army medical research and materiel command clinical and Rehabilitative Medicine Research Program Research Area Directorate 5. ATTN: MCMR-RTR, 504 Scott Street BLDG 722, Fort Detrick, MD 21702. Submitted 2012; awarded 2013.

“Treatment of Corneal Epithelial Wound Using A Novel Sustained Drug Delivery of Human Growth Hormone.” Dr. Wirostko is providing strategic and technical oversight without compensation. CRADA in place for non-GLP proof of concept preclinical work to occur at USAISR using novel burn models NOT included in the BAA proposal. Jade will supply the needed drug loaded delivery materials.

PI: Col. Anthony Johnson, MD, Task Area Manager of US Army Institute of Surgical Research; CO-I: Barbara M Wirostko, MD, 5 percent effort.

Title/#/ Solicitation Date: Internal Core Funds AIBS NO:120336. CRADA in place between Jade and USAIRS for this preclinical work.

2012Barbara M Wirostko, MD, through Jade, has submitted an NSF SBIR-Phase I Solicitation FY-2013; 12-605 (BM3). Grant has been awarded in 2013.

2011-2012Patents Pending filed by Jade Therapeutics, Inc.:

Application #1 US Patent No. 61/62, 4730 (Filed 2011)“Corneal Wound Healing.”

Application #2 US Patent No. 61/58, 1845 (Filed 2012) “Dermal Wound Healing.”

Application # 3 Provisional US Patent No. 3246-005 (Filed 2012) “Corneal Re Innervation.”

J o H N A . M o R A N E y E C E N T E R

Fo

cu

s 2

013

66

Fo

cu

s 2

013

67

January 11 Marielle Young, MD The Diagnosis & Management of Ocular Torsion

Lloyd Williams, MD South Sudan

January 18 Krista Kinard, MD, Resident Restriction vs Dysinnervation

January 25 Mark Michelson, MD, Associate Clinical Professor Pseudophakic Accommodation: of Ophthalmology & Director of Cornea, University Another Perspective of Alabama, Birmingham

February 1 Alan S Crandall, MD Femtosecond & Ultrachopper

February 8 Balamurali K Ambati, MD, PhD, MBA Soluble FLT-1: From Wellspring of Avascularity to Springboard for Anti-Angiogenics

Brian Zaugg, MD, Resident Ocular Lymphoma

February 15 Tony Adamis, VP & Global Head of Ophthalmology Next Steps in AMD at Genetech

February 22 Jason Goldsmith, MD Cognitive Errors in Medical Decision Making

February 29 Barbara M Wirostko, MD Research Opportunities at the Moran

Joyce Mitchell, Biomedical, University of Utah clinical cohort Finding with the FUrtHer System

March 7 Jim Bell, MD, Resident Acute Unilateral Vision Loss with Stiffness

Angela Peters, MD, Neurology Resident NARP: Neurogenic Muscle Weakness, Ataxia & Retinitis Pigmentosa

March 14 Gregory S Hageman, MD A New Era in Our Understanding of Age-related Macular Degeneration

March 21 Dr. Sanduk Ruit, Founder of the Tilganga Eye Overcoming Cataract Blindness in the Institute & Lead Partner of Moran’s International Developing World Division of ophthalmology

March 28 Michael Varner, MD, Professor, University of Utah Personalized Health Care OBGYN

April 11 Kathleen B Digre, MD, Moran/Eccles Library Using Library Resources to Enhance your Career

April 18 Dan Bettis, MD Unexplained Vision Loss

April 25 Todd Cahoon, Medical Student, University of Utah COMP.Ang1-induced Vascular Normalization Enhances Visual Structure and Function in Murine Type 1 Diabetic Retinopathy

May 9 Sabine Fuhrmann, PhD Extracellular Signals Regulating eye Development

May 23 Leah Owen, MD, Resident Bad Eyes & Bad Ears Run in the Family— Early Onset Vision and Hearing Loss

May 30 Zachary Joos, MD Intern Floaters, Fatigue, and Forgotten Insulin

Briana Sawyer, Genetic Counselor, Introduction to Genetic Counseling ophthalmology Services

June 6 Gene Kim, MD Confocal Microscopy of the Cornea: Clinical Applications & Standardizing Data Acquisition + Neuroretinitis vs. Optic Neuritis

June 13 Maylon Hsu, MD DSAEK Ultra Thin Grafts & Complication & Outcomes of Challenging Cases + A Big Blind Spot

June 20 Tom Oberg, MD, Resident Cryoprin Associated Periodic Syndromes & the Eye + Gial Cell Arteritis: Spectrum and Future

July 18 Nick Behunin, MSIV, Keratoconus Treatments University of Utah

Scott Butikofer, MSIV, Enterobacter Cloacae Post-surgical University of Washington SOM Endophthalmitis

Rachel Simpson, MSIV, Ocular Complications of Diabetes University of Arizona COM

D A T E P R E S E N T E R T o P I C o R T I T L E

2012Grand Rounds

July 25 Lucas Lenci, MSIV, Orbital Cellulitis University of Missouri Columbia SOM

John Bennion, Ocular Manifestations of Inflammatory West Virginia University Health Sciences Bowel Disease

Gary Nelson, MD, Neurology Resident Third Nerve Palsy

August 8 Alan S Crandall, MD Update on Minimally Invasive Glaucoma Surgery

August 15 Steve Christensen, MSIV, University of Utah Keratometric Changes after Refractive Surgery

Gavin Roddy, MSIV, Adult Stem/Progenitor Cells & Their Secreted Texas A&M Health Sciences COM Proteins for the Treatment of Ocular Disease

August 22 Andrew Rodenburg, MSIV, Ophthalmology: The Digital Age University of North Dakota SOM

Chris Smith, MSIV, Comparison of Noncontact & Contact Confoval University of Texas Medical Branch Microscopy after Descemet’s Stripping Automated Endothelial Keratoplasty

August 29 Zach Oakey, MSIV, University of Utah Keratoconus, Anatomy, Pathology, and Case Presentation

Bryce Radmall, MSIV, University of Utah Vision of the Homeless: The Moran Eye Center at the Fourth Street clinic

September 5 Paul S Bernstein, MD, PhD, & Brianna Sawyer, Genetic Counseling in Ophthalmology Genetic Counselor, Ophthalmology Services

September 12 Ronnie Bhola, MD Trocar Assisted Sutureless Scleral Fixation Visiting Physician, Trinidad/Tobago of Posterior Chamber IOL Viscodissection Diabetic Delamination

September 19 Chad Jackson, MSIV, University of Kentucky COM Birdshot or Not? Birdshot Retinachoroidopathy

Jason Hooten, MSIV, Terrien’s Marginal Degeneration Case University of Washington SOM Presentation & Discussion

Peter Ririe, MSIV, University of Texas SW a novel model for Studying Fibroblast Medical Center at Dallas Migration through Fibrin Matricies

September 26 Zachary Joos, MD Clinical Case: A twenty-year-old with encephalopathy & Scotoma

October 10 Brian Stagg, MD, Intern Pre-operative Medical Assessment of Patients Undergoing eye Surgery

Allison Jarstad, MSIV, Pacific Northwest Child with Rapidly Progressive Proptosis University of Health Sciences

October 17 Bhupendra C K Patel, MD, FRCS, FRC Procedures for Ophthalmologists: Part 1. Video Presentation with Tips

October 24 Trent Richards, MD Patient with Multiple Branch Retinal artery occlusions

October 31 Brian Zaugg, MD, Resident Intraoperative Floppy Iris Syndrome

November 7 Randall J Olson, MD What Does Optical Quality Mean and What Can It Tell Us

November 14 Jim Bell, MD Red Eyes & Intubated: A Uveitic Curiosity

Chung Lee, MD, Neurology Resident Word Blindness

November 28 Nick Mamalis, MD Pathology of PX

Liliana Werner, MD, PhD IOL/CTR Subluxation/Dislocation

Jeff Pettey, MD Sleep Deprivation

December 5 Dan Bettis, MD Wait…Can you Fake That?

December 12 Peter Barabas, PostDoc in Krizaj Lab Mouse Models of STGD3

D A T E P R E S E N T E R T o P I C o R T I T L E

2012Grand Rounds

Fo

cu

s 2

013

68

Fo

cu

s 2

013

69

Advances in Experimental Medicine & BiologyXing W, Akopian A, Krizaj D. Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 alpha1 subunits. Adv Exp Med Biol 2012; 723:739-744

American Journal of Human GeneticsTantravahi SK, Williams LB, Digre KB, Creel DJ, Smock KJ, DeAngelis M, Clayton FC, Vitale AT, Rogers GM. An inherited disorder with splenomegaly, cytopenias, and vision loss. Am J Hum Genet 2012; 201;158, 475-81

American Journal of Ophthalmology Lim JH, Wickremasinghe SS, Xie J, Chauhan DS, Baird PN, Robman LD, Hageman GS, Guymer RH. Delay to treatment and visual outcomes in patients treated with anti-vascular endothelial growth factor for age-related macular degeneration. Am J Ophthalmol 2012; 153(4), 678-86

Dhital A, Spalton DJ, Goyal S, Werner L. Calcification in hydrophilic intraocular lenses associated with injection of intraocular gas. Am J Ophthalmol 2012 Jun; 153(6):1154-60.e1

American Journal of Pathology Wang H, Byfield G, Jiang Y, Smith GW, McCloskey M, Hartnett ME. VEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoietin expression. Am J Pathol 2012; 180(3), 1243-53

Archives of Biochemistry and Biophysics Vachali P, Li B, Nelson K, Bernstein PS. Surface plasmon resonance (SPR) studies on the interactions of carotenoids and their binding proteins. Arch Biochem Biophys 2012; 519(1), 32-37

Archives of OphthalmologyFrandsen JE, Llop S, Digre KB, Bernstein PS, Sharifzadeh M, Warner JE, Gellerman W, Katz BJ. Quantification of macular carotenoids using autofluorescence imaging in patients with photosensitive migraine and benign essential blepharospasm. Arch Ophthalmol 2012; 130(2), 259-60

Bourne R, Price H, Stevens G, Hartnett ME, GBD Vision Loss Expert Group. Global burden of visual impairment and blindness. Arch Ophthalmol 2012; 130(5), 645-7

Wu C, Lofqvist C, Smith L, VanderVeen DK, Hellstrom A, Hartnett ME, WINROP Consortium. Importance of early postnatal weight gain for normal retinal angiogensis in very preterm Infants. Arch Ophthalmol 2012; 1-8

Kopplin LJ, Przepyszny K, Schmotzer B, Rudo K,

Babineau DC, Patel SV, Verdier DD, Jurkunas U, Iyengar SK, Lass JH, Fuchs Endothelial Corneal Dystrophy Genetics Multi-center Study Group (Mifflin MD). Relationship of Fuchs endothelial corneal dystrophy severity to central corneal thickness. Arch Ophthalmol 2012; 130(4), 433-439

Espandar L, Bunnell B, Wang GY, McBride C, Moshirfar M. Adipose-derived stem cells on hyaluronic acid-derived scaffold: a new horizon in bioengineered cornea. Arch Ophthalmol 2012; (6), 213-8

Digre K, Warner J, Katz B, Gilman J. Imaging characteristics of myelinated retinal nerve fiber layer. Arch Ophthalmol 2012

British Journal of Ophthalmology Cherepanoff S, Killingsworth MC, Zhu M, Nolan T, Hunyor AP, Young SH, Hageman GS, Gillies MC. Ultrastructural and clinical evidence of subretinal debris accumulation in type 2 macular telangiectasia. Br J Ophthalmol 2012

Zore M, Harris A, Tobe LA, Siesky B, Januleviciene I, Behzadi J, Amireskandari A, Egan P, Garff K, Wirostko BM. Generic medications in ophthalmology. Br J Ophthalmol 2012 Nov 9

British Medical JournalWirostko BM, Tressler C, Hwang LJ, Burgess G, Laties AM. ocular safety of sildenafil citrate when administered chronically for pulmonary arterial hypertension: results from a phase 3, randomised, double-masked, placebo-controlled trial and 2 year open label extension. British Medical Journal 2012 Feb 21; 344:e554

Canadian Journal of Ophthalmology Sorensen T, Chan CC, Bradley M, Braga-Mele R, olson RJ. A comparison of cataract surgical practices in Canada and the United States. Can J Ophthalmol 2012; 47(2),131-9

Cell Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, Ponicsan SL, Chaudhuri G, Murphy MP, Dunaief JL, Ambati BK, Ogura Y, Yoo JW, Lee DK, Provost P, Hinton DR, Nunez G, Baffi JZ, Kleinman ME, Ambati J. DICER1 loss and Alu RNA induced age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012; 149(4),847-59

Cerebral CortexJeffs J, Federer F, Ichida JM, and Angelucci A. High-resolution mapping of anatomical connections in marmoset extrastriate cortex reveals a complete representation of the visual field bordering dorsal V2. Cerebral Cortex 2012; doi:10.1093

Clinical & Experimental OphthalmologyShoshani Y, Harris A, Shoja MM, Arieli Y, Ehrlich R, Primus S, Ciulla T, Cantor A, Wirostko B, Siesky BA. Impaired ocular blood flow regulation in patients with open angle glaucoma and diabetes. Clin Experiment Ophthalmol 2012 Sep; 40(7):697-705

Clinical OphthalmologyChristiansen SM, Mifflin MD, Edmonds JN, Simpson RG, Moshirfar M. Astigmatism induced by conventional spherical ablation after PRK and LASIK in myopia with astigmatism <1.00 D. Clin Ophthalmol 2012; 6,2109-17

Khakshoor H, Moshirfar M, Simpson RG, Garaee H, Vejdani AH, Christiansen SM, Edmonds JN, Behunin NL. Anesthetic keratopathy presenting as bilateral Mooren-like ulcers. Clin Ophthalmol 2012; (6), 1719-22

Simpson RG, Moshirfar M, Edmonds JN, Christiansen SM, Behunin N. Laser in situ keratomileusis in patients with collagen vascular disease: a review of the literature. Clin Ophthalmol 2012; (10), 2147

Simpson RG, Moshirfar M, Edmonds JN, Christiansen SM. Laser in-situ keratomileusis in patients with diabetes mellitus: a review of the literature. Clin Ophthalmol 2012; (6), 1665-74

Mifflin MD, Leishman LL, Christianse SM, Sikder S, Hus M, Moshirfar M. Use of lotoprednol for routine prophylaxis after photorefractive keratectomy. Clin Ophthalmol 2012; (6), 653-9

Huse M, Hereth WL, Moshirfar M. Double-pass microkeratome technique for ultra-thin graft preparation in Descemet’s stripping automated endothelial keratoplasty. Clin Ophthalmol 2012; (6), 425-432

Moshirfar M, Ollerton A, Semnani RT, Hau M. Radial keratotomy associated endothelial degeneration. Clin Ophthalmol 2012; (6), 213-8

Cornea Cho YK, Uehara H, Young JR, Archer B, Ambati BK. Pretreatment in a murine penetrating keratoplasty and suture model. Cornea 2012

Moshirfar M, Khalifa YM, Davis D, Fenzl CR, Espandar L, Change JC, Mamalis N, Mifflin MD. Descement stripping automated endothelial keratoplasty using donor corneas with previous laser in situ keratomileusis or photorefractive keratectomy: a case series and donor cap histopathology. Cornea 2012; 31(5), 533-537

Louttit MD, Kopplin LJ, Igo RP, Fondran JR, Tagliaferri A, Bardenstein D, Aldave AJ, Croasdale CR, Price MO, Rosenwasser GO, Lass JH, Iyengar SK, FECD Genetics Multi-center Study Group (Mifflin MD). A multicenter study

A sample of more than 200 published and presented materials by Moran faculty members between January 1 and December 31, 2012

P U B L I S H E D R E S E A R C Hto map genes for Fuchs endothelial cornea dystrophy: baseline characteristics and heritability. Cornea 2012; 31(1), 26-35

Sugar A, Montoya MM, Beck R, Cowden JW, Dontchev M, Gal RL, Kollman C, Malling J, Mannis MJ, Tennant BA, Cornea Donor Study Investigator Group (Mifflin MD). Impact of the cornea donor study on acceptance of corneas from older donors. Cornea 2012; 31(12), 1441-1445

Calvo CM, Sikder S, Mamalis N, Mifflin MD. Linear interstitial keratitis: a distinct clinical entity revisited. Cornea 2012; 31(12), 1500-1503.

Stulting RD, Sugar A, Beck R, Belin M, Dontchev M, Feder RS, Gal RL, Holland EJ, Kollman C, Mannis MJ, Price F Jr, Stark W, Verdier DD, Cornea Donor Study Investigator Group (Mifflin MD). Effect of donor and recipient factors on corneal graft rejection. Cornea 2012; 31(10),1141-1147

Hsu M, Jorgensen AJ, Moshirfar M, Mifflin MD. Management and outcomes of descemet stripping automated endothelial keratoplasy with intraocular lens exchange, aphakia, and anterior chamber intraocular lens. Cornea 2012

Moshirfar M, Kim G. The role of host endothelial cell proliferation in descemet membrance endothelial transfer. Cornea 2012

Current Eye ResearchShoshani Y Z, Harris A, Shoja MM, Rusia D, Siesky B, Arieli Y, and Wirostko B. Endothelin and its suspected role in the pathogenesis and possible treatment of glaucoma. Curr Eye Res 2012 Jan; 37(1):1-11

Current Opinion in NeurobiologyMarc RE, Anderson JR, Jones BW, Watt CB. Building retinal connectomes. Curr Opin Neurobiol 2012 April; 22:568-574

Current Opinion in Ophthalmology Holt DG, Young J, Stagg B, Ambati BK. Anterior chamber intraocular lens, sutured posterior chamber intraocular lens, or glued intraocular lens: where do we stand? Curr Opin Ophthalmol 2012; 23(1), 62-7

Developmental Dynamics Das G, Clark AM, Levine EM. Cyclin D1 inactiva-tion extends proliferation and alters histogen-esis in the postnatal mouse retina. Develop-mental Dynamics, 2012; 241:941-952

Diabetologia Maile LA, Gollahon K, Wai C, Byfield G, Hartnett ME, Clemmons D. Disruption of the associa-tion of integrin-associated protein (IAP) with tyrosine phosphatase non-receptor type substrate-1 (SHPS)-1 inhibits pathophysiologi-cal changes in retinal endothelial function in a rat model of diabetes. Diabetologia 2012; 55(3), 835-44

EyeNet Magazine Crandall AS. Case 4: fun with zonules (not). EyeNet 2012; (2),48-9.

European Journal of Clinical Nutrition Scarmo S, Henebery K, Peracchio H, Cartmel B, Lin H, Ermakov IV, Gellermann W, Bernstein PS, Duffy VB, Mayne ST. Skin carotenoid status measured by resonance Raman spectroscopy as a biomarker of fruit and vegetable intake in preschool children. Eur J Clin Nutr 2012; 66(5), 555-60

European Journal of Neuroscience Seiler MJ, Jones BW, Aramant RB, Yang PB, Kei-rstead HS, Marc RE. Computational molecular phenotyping of retinal sheet transplants to rats with retinal degeneration. Eur J Neurosci 2012 June; 35(11), 1692-1704

Federation of American Societies for Experimental Biology JournalUehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK. Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR). FASEB J 2012

Lin Y, Jones BW, Liu A, Tucker JF, Rapp K, Luo L, Baehr W, Bernstein PS, Watt CB, yang JH, Shaw MV, Marc RE. Retinoid receptors trigger neuritogenesis in retinal degenerations. FASEB J 2012; 26(1), 81-92

Genome MedicineNewman AM, Gallo NB, Hancox LS, Miller NJ, Radeke CM, Maloney MA, Cooper JB, Hageman GS, Anderson DH, Johnson LV, Radeke MJ. Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks. Genome Medicine 2012; 4(2), 16

Human Molecular GeneticsWang L, Zou J, Shen Z, Song E, yang J. Whirlin interacts with espin and modulates its actin-regulatory function: an insight into the mechanism of Usher syndrome type II. Hum Mol Genet 2012; 21(3), 692-710

IEEE Image ProcessingVignesh Jagadeesh, BS Manjunath, BS Anderson, James R, Jones Bryan W, Marc Robert E, Steven Fisher. Parameter estimation in dynamic markov random fields for image sequence analysis. IEEE Image Processing 2012; Online

International Ophthalmology ClinicsShakoor A, Vitale AT. Imaging in the diagnosis and management of multifocal choroiditis and punctate inner choroidopathy. Inter Ophth Clinic, 2012; 52(4), 243-256

Investigative Ophthalmology and Visual SciencesQazi Y, Stagg B, Singh N, Singh S, Zhang X, Luo L, Simonis J, Komeplla UB, Ambati BK. Nanoparticle-mediated delivery of shRNA.VEGF-aplasmids regresses corneal neovascularization. Invest Ophthalmol Vis Sci 2012; 53(6), 2837-44

Cho YK, Uehara H, Young JR, Tyagi P, Kompella UB, Zhang X, Luo L, Sigh N, Archer B, Ambati BK. Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone. Invest Ophthalmol Vis Sci 2012; 53(4), 2328-36

Cho YK, Uehara H, Young JR, Archer B, Zhang X, Ambati BK. Vascular endothelial growth factor receptor 1 morpholino decreases angiogenesis in a murine corneal suture model. Invest Ophthalmol Vis Sci 2012; 53(2), 685-92

Bernstein PS, Ahmed F, Liu A, Allman S, Sheng X, Sharifzadeh M, Ermakov I, Gellermann W. Macular pigment imaging in AREDS2 participants: an ancillary study of AREDS2 subjects enrolled at the Moran Eye Center. Invest Ophthalmol Vis Sci 2012; 53(10), 6178-86

Daniels AB, Lee JE, MacConaill LE, Palescandolo E, Van Hummelen P, Adams SM, DeAngelis MM, Hahn WC, Gragoudas ES, Harbour JW, Garraway LA, Kim IK. High throughput mass spectrometry-based mutation profiling of primary uveal melanoma. Invest Ophthalmol Vis Sci 2012 Oct 9; 53(11):6991-6

Zhang T, Baehr W, Fu y. Chemical chaperone TUDCA preserves cone photoreceptors in a mouse model of Leber congenital amaurosis. Invest Ophthalmol Vis Sci 2012; 53(7), 3349-3356

Ross JW, Fernandez de Castro JP, Zhao J, Samuel M, Walters E, Rios C, Bray-Ward P, Jones BW, Marc RE, Wang W, Zhou L, Noel JM, McCall MA, DeMarco PJ, Prather RS, Kaplan HJ. Generation of an inbred miniature pig model of retinitis pigmentosa. Invest Ophthalmol Vis Sci 2012 January; 53(1), 501-507

Japanese Journal of OphthalmologyJones BW, Kondo M, Terasaki H, Lin Y, McCall M, Marc RE. Retinal remodeling. Jpn J Ophthalmol 2012; 56(4), 289-306

Journal of AAOPSBlair MP, Shapiro MJ, Hartnett ME. Fluorescein-anaiography to estimate normal peripheral retinal nonperfusion in children. J AAPOS 2012; 16(3), 234-7

young MP, Heidary G, VanderVeen DK. Relationship between the timing of cataract surgery and develpment of nystagmus in patients with bilateral infantile cataracts. J AAPOS 2012; 16(6), 554-7

Journal of Cataract & Refractive SurgeryMoshirfar M, Kim G. Complications related to the explanation of cosmetic iris implants. J Cataract Refract Surg 2012; 38(10), 1876-7

Slade DS, Hater MA, Cionni RJ, Crandall AS. Ab externo scleral fixation of intraocular lens. J Cataract Refract Surg 2012; 38, 1316-2

McIntyre JS, Werner L, Fuller SR. Kavouissi AC, Hill M, Mamalis N. Assesment of a single-piece hydrophilic acrylic IoL for piggyback sulcus fixation in pseudophakic cadaver eyes. J Cataract Refract Surg 2012 Jan 1; 38, 155-62

Bodnar Z, Clouser S, Mamalis N. Toxic anterior segment syndrome: update on the most common causes. J Cataract Refract Surg 2012; 38,1902-10

Goecks T, Werner L, Mamalis N, Fuller SR, Jensen M, Kavoussi SC, Hill M, olson RJ. Toxicity

Fo

cu

s 2

013

70

Fo

cu

s 2

013

71

comparison of intraocular azithromycin with and without a bioadhesive delivery system in rabbit eyes. J Cataract Refract Surg 2012; 38(1), 137-145

oberg TJ, Sikder S, Jorgensen AJ, Mifflin MD. Topical-intracameral anesthesia without preoperative mydriatic agents for Descemet-stripping automated endothelial keratoplasty and phacoemulsification cataract surgery with intraocular lens implantation. J Cataract Refract Surg 2012; 38 (3), 384-6

Holt DG, Sikder S, Mifflin MD. Surgical management of traumatic LASIK flap dislocation with macrostriae and epithelial ingrowth 14 years postoperatively. J Cataract Refract Surg 2012; 38(2), 357-61

Moshirfar M, Kim G. May consultation #2. J Cataract Refract Surg 2012; (6), 459-64

DeMill DL, Zaugg BE, Pettey JH, Jensen JD, Jardine GJ, Wong G, olson RJ. objective comparison of 4 nonlongitudinal ultrasound modalities regarding efficiency and chatter. J Cataract Refract Surg 2012; 38(6), 1065-1071

Stringham J, Pettey JH, olson RJ. Evaluation of variables affecting intraoperative aberrometry. J Cataract Refract Surg 2012 Mar; 38(3), 470-4

Ollerton A, Werner L, Fuller SR, Kavoussi SC, McIntyre JS, Mamalis N. Evaluation of a new single-piece 4% water content hydrophobic acrylic intraocular lens in the rabbit model. J Cataract Refract Surg 2012 Oct; 38(10):1827-32

Leishman L, Werner L, Bodnar Z, Ollerton A, Michelson J, Schmutz M, Mamalis N. Prevention of capsular bag opacification with a modified hydrophilic acrylic disk-shaped intraocular lens. J Cataract Refract Surg 2012 Sep; 38(9), 1664-70

Werner L, Michelson J, Ollerton A, Leishman L, Bodnar Z. Anterior segment optical coherence tomography in the assessment of postoperative intraocular lens optic changes. J Cataract Refract Surg 2012 Jun; 38(6), 1077-85

Jaber R, Werner L, Fuller S, Kavoussi SC, McIntyre S, Burrow M, Mamalis N. Comparison of capsulorhexis resistance to tearing with and without trypan blue dye using a mechanized tensile strength model. J Cataract Refract Surg 2012 Mar; 38(3), 507-12

Werner L, Wilbanks G, Ollerton A, Michelson J. Localized calcification of hydrophilic acrylic intraocular lenses in association with intracameral injection of gas. J Cataract Refract Surg 2012 Apr; 38(4), 720-1

Michelson J, Werner L, Ollerton A, Leishman L, Bodnar Z. Light scattering and light transmittance in intraocular lenses explanted because of optic opacification. J Cataract Refract Surg 2012 Aug; 38(8), 1476-85

Sorensen T, Chan CC, Bradley M, Braga-Mele R, olson RJ. Ultrasound-induced corneal incision contracture survey in the United States and Canada J Cataract Refract Surg. 2012 Feb; 38(2):227-33

Journal of Clinical Neuroscience French KF, Hoesch RE, Allred J, Wilder M, Smith AG, Digre KB, La Barge DV 3rd. Repetitive use of intra-arterial verapamil in the treatment of reversible cerebral vasoconstriction syndrome. J Clin Neurosci 2012; 19(1), 174-6

Irak-Dersu I, Thostenson J, Durcan FJ, Hamilton SM, Digre KB. optic disc and visual findings in migraine patient. J Clinical Neuroscience. 2012; 24 September Online

Journal of Comparative Neurology Lauritzen JS, Anderson JR, Jones BW, Watt CB, Mohammed S, Hoang JV, Marc RE. oN cone bipolar cell axonal synapses in the oFF inner plexiform layer of the rabbit retina. J Comp Neurol 2012 Oct 8

Journal of Developmental BiologyKruse-Bend R, Rosenthal J, Quist TS, Veien ES, Fuhrmann S, Dorsky RI, Chien CB. Extraocular ectoderm triggers dorsal retinal fate during optic vesicle evagination in zebrafish. Dev Biol 2012; 371, 57-65

Al Diri I, Vetter ML. PRC2 during vertebrate organogenesis: a complex in transition. Dev Biol 2012; 367:91-99

Journal of GlaucomaHoffman RS, Crandall AS, Crandall DA, Fine IH, Packer M, Sims AC. Minimally invasive external mini-glaucoma shunt implantation without conjunctival dissection. J Glaucoma 2012

Stewart WC, DeMill DL, Wirostko BM, Nelson LA, Stewart JA. Review of the influence of pigment dispersion and exfoliation glaucoma diagnosis on intraocular pressure in clinical trials evaluating primary open-angle glaucoma and ocular hypertension. J Glaucoma 2012 Jan 20

Journal of Neural EngineeringRA Normann, Dowden BR, Frankel MA, Wilder AM, Hiatt SD, Ledbetter NM, Warren DA, Clark GA. Coordinated, multi-joint, fatigue-resistant feline stance produced by Utah slanted electrode arrays in hind limb nerves. J Neural Eng 2012 Apr; 9(2):026019

Journal of Neuro-OphthalmologyDigre KB, Brennan KC. Shedding light on photophobia. J Neuro-ophthalmol 2012; 32(1), 68-81

Shelton JB, Digre KB, Katz BJ, Warner JE. Chiasmal stroke in patient with atrial fibrillation and complete occlusion of right internal carotid artery. J Neuro-ophthalmol 2012

Shelton JB, Digre KB, Katz BJ, Warner JE. Reversible prolonged bilateral inferior altitudinal visual field defects associated with migraine. J Neuro-ophthalmol 2012

Journal of Neuroscience Shushruth, Mangapathy P, Ichida JM, Bressloff PC, Schwabe L, Angelucci A. Strong recurrent networks compute the orientation-tuning of surround modulation in the primate primary visual cortex. J. Neurosci 2012; 32:308-321

Lee D, Chona FV, Ferrell W, Tam B, Jones BW, Marc RE, Moritz O. Dysmorphic photoreceptors in a P23H mutant rhodopsin model of retinitis pigmentosa are metabolically active and capable of regenerating to reverse retinal degeneration. J Neurosci 2012 Feb; 32(6), 2121-2128

Journal of Ophthalmology Moshirfar M, Hsu M, Schulman J, Armenia J, Sikder S, Hartnett ME. The incidence of central serous chorioretinopathy after photorefractive keratectomy and laser in situ keratomileusis. J Ophthalmol 2012; 27-32

Shelton JB, Digre KB, Katz BJ, Warner JE, Quigley EP. Chiasmal stroke in patient with atrial fibrillation and complete occlusion of right internal carotid artery. J Ophthalmol 2012; 32(2),189

Journal of Pediatric Gastroenterology Chan GM, Chan MM, Gellermann W, Ermakov I, Ermakova M, Bhosale P, Bernstein P, Rau C. Resonance raman spectroscopy and the preterm infant carotenoid status. J Pediatr Gastroenterol Nutr 2012

Journal of PhysiologyMolnar T, Barabas P, Birnbaumer L, Punzo C, Kefalov V and Krizaj D. Store-operated channels regulate intracellular calcium in mammalian rods. Journal of Physiology 2012; 590: 3465

Journal of Proteome ResearchLen AC, Powner MB, Zhu L, Hageman GS, Song X, Fruttiger M, Gillies MC. Pilot application of iTRAQ to the retinal disease macular telangiectasia. J Proteome Res 2012; 11(2), 537-53

Journal of Refractive Surgery Mifflin MD, Hatch BB, Sikder S, Kurz CJ, Moshirfar M. Custom vs conventional PRK: a prospective, randomized, contralateral eye comparison of postoperative visual function. J Refract Surg 2012; 28(2), 127-32

Moshirfar M, Christiansen SM, Kim G. Comparison of the ratio of keratometric change to refractive change induced by myopic ablation. J Refract Surg 2012; 28(10), 675-82

Middle Eastern African Journal of Ophthalmology Moshirfar M, Anderson E, Hsu M, Armenia JM, Mifflin MD. Comparing the rate of regression after conductive keratoplasty with or without prior laser-assisted in situ keratomileusis or photorefractive keratectomy. Middle East Afr J Ophthalmol 2012; 19(4),376-81

Molecular Neurodegeneration Lin Y, Jones BW, Liu A, Vazquéz-Chona FR, Lauritzen JS, Ferrell WD, Marc RE. Rapid glutamate receptor 2 trafficking during retinal degeneration. Mol Neurodegener. 2012 Feb; 10;7:7. doi: 10.1186/1750-1326-7-7

Molecular Vision Baas DC, Ho L, Tanck MW, Fritsche LG, Merriam JE, van Het Slot R, Koeleman BP, Gorgels TG, van Duijn CM, Uitterlinden AG, de Jong PT, Hofman A, Ten Brink JB, Vingerling JR, Klaver CC, Dean M, Weber BH, Allikmets R, Hageman GS, Bergen AA. Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. Mol Vis 2012; 18, 657-74

Nepal Journal of OphthalmologyThapa R, Poudyal G, Maharjan N, Bernstein PS. Demographics and awareness of diabetic retinopathy among diabetic patients attending the vitreo-retinal service at a tertiary eye care center in Nepal. Nepal J Ophthalmol 2012; 4(7), 10-6

NeurocaseAfra P, Anderson J, Funke M, Johnson M, Matsuo F, Constantino T, Warner JE. Neurophysiological investigation of idiopathic acquired auditory-visual synesthesia. Neurocase 2012; 18(4),323-9

Neuro-Oncology Fisher MJ, Loguidice M, Gutmann DH, Listernick R, Ferner RE, Ullrich NJ, Pakcer RJ, Tabori U, Hoffman Ro, Ardern-Holmes SL, Hummel TR, Hargrave DR, Bouffet E, Charrow J, Bilaniuk LT, Balcer LJ, Liu GT. Visual outcomes in children with neurofibromatosis type 1-associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis. Neuro-Oncol 2012; (2), 1-8

New England Journal of Medicine Hartnett ME, Penn JS. Mechanisms and management of retinopathy of prematurity. N Engl J Med 2012; 367(26), 15-26

Ocular Immunology and In�ammation Morshedi RG, Bettis DI, Moshirfar M, Vitale AT. Bilateral acute iris transillumination following systemic moxifloxacin for respiratory illness: report of two cases and review of the literature. Ocul Immunol Inflamm 2012

Oman Journal of OphthalmologyKhakshoor H, Moghaddam AA, Vejdani AH, Armstrong BK, Moshirfar M. Diplopia as the primary presentation of foodborne botulism. Oman J Ophthalmol 2012; 5(2),109-11

Oncol Rep Yu K, Chen Z, Pan X, Yang Y, Tian S, Zhang J, Ge J, Ambati B, Zhuang J. Tetramethylpyrazine-mediated suppression of C6 gliomas involves inhibition of chemokine receptor CxCR4 expression. Oncol Rep 2012; 28(3), 955-60

Open Ophthalmology Journal Betts BS, oberg TJ, Hsu M, Moshirfar M. Choroidal neovascularization following implantation of verisyse iris-supposed phakic intraocular lens in a pregnant myopic patient. Open Ophthalmol J 2012; (6),6-7

Ophthalmology Mwanza JC, Durbin MK, Budenz DL, Sayyad FE, Change RT, Neelakantan A, Godfrey DG, Carter R, Crandall AS. Glaucoma diagnostic accuracy of ganglion cell-inner plexiform layer thickness: comparison with nerve fiber layer and optic nerve head. Ophthalmology 2012; 119(6),1151-8

Kirk KR, Werner L, Jaber R, Strenk S, Strenk L, Mamalis N. Pathologic assessment of complications with asymmetric or sulcus fixation of square-edged hydrophobic acrylic intraocular lenses. Ophthalmology 2012; 119,907-913

Werner L, Zaugg B, Neuhann T, Burrow M, Tetz M. In-the-bag capsular tension ring and intraocular lens subluxation or dislocation: a series of 23 cases. Ophthalmology 2012 Feb; 119(2):266-71

Ophthalmic Research DeMill DL, Wirostko BM, Nelson LA, Stewart JA, Stewart WC. Average eye versus highest intraocular pressure analyses in glaucoma clinical trials. Ophthalmic Res 2012; 49:49-51

Ophthalmic Surgery, Lasers & Imaging Saffra N, Agarwal S, Enin J, Werner L, Mamalis N. In vitro analysis of Nd:yAG laser damage to hydrophilic intraocular lenses. Ophthalmic Surg Lasers Imaging 2012 Jan-Feb; 43(1):45-9

Pharmaceutics Gooch N, Molokhia SA, Condie R, Burr RM, Archer B, Ambati BK, Wirostko BM. ocular drug delivery for glaucoma management. Pharmaceutics 2012

PLoS Genetics Zou C, Levine EM. Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high-affinity DNA binding. PLoS ONE 2012; 7(3), e33576

PLoS One owen LA, Uehara H, Cahoon J, Huang W, SimonisJ, Ambati BK. Morpholino-mediated increase in soluble Flt-1 expression results in decreased ocular and tumor neovascularization. PLoS ONE 2012; 7(3), e33576

Parmalee NL, Schubert C, Figueroa M, Bird AC, Peto T, Gillies MC, Bernstein PS, Kiryluk K, Terwilliger JD, Allikmets R. Identification of a potential susceptibility locus for macular telangiectasia type 2. PLoS ONE 2012; 7(8), e24268

Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H. Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS One 2012; 7(4):e35295

Igo RP Jr, Kopplin LJ, Joseph P, Truitt B, Fondran J, Bardenstein D, Aldave AJ, Croasdale CR, Price MO, Rosenwasser M, Lass JH, Iyengar SK, FECD Genetics Multi-center Study Group (Mifflin MD). Differing roles for TCF4 and CoL8A2 in central corneal thickness and fuchs endothelial corneal dystrophy. PLoS ONE 2012; 7(10),e46742

Proceedings of the National Academy of Sciences of the United States Dridi S, Hirano Y, Tarallo V, Kim Y, Fowler BJ, Ambati BK, Bogdanovich, Chiodo VA, Hauswirth WW, Kugel JF, Goodrich JA, Ponicsan SL, Hinton DR, Kleinman ME, Baffi JZ, Gelfand BD, Ambati J. ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proc Natl Acad Sci U S A 2012; 109(34),13781-6

Retinal Physician Colucciello M, Vitale AT, Smet M de. Pars Plana vitrectomy for the induction of drug-free remission in uveitis: It’s too soon to tell if PPV is the right way to go in treating uveitis. Retinal Physician, 2012; 9(2):18-22

Vision ResearchZhang H, Constantine R, Frederick JM, Baehr W. The prenyl-binding protein PrBP/δ: a chaperone involved in intracellular trafficking. Vision Res 2012; 75, 19-25

Ronquillo CC, Bernstein PS, Baehr W. Senior-Løken Syndrome: A syndromic form of retinal dystrophy associated with nephronophthisis. Vision Res 2012. 75, 88-97

Constantine R, Zhang H, Gerstner CD, Frederick JM, Baehr W. Uncoordinated(UNC)119: coordinating the trafficking of myristoylated proteins. Vision Res 2012; 75, 26-32

Khanna H, Baehr W. Retina ciliopathies: from genes to mechanisms and treatment. Vision Res 2012; 75, 1

Zou J, Lee A, yang J. The expression of whirlin and Ca(v)1.3alpha(1) is mutually independent in photoreceptors. Vision Res 2012; 75,53 - 5

Books PublishedFoster CS, Vitale A. Diagnosis and Treatment of Uveitis, Second Edition. Jaypee Brothers Medical Publishers, New Delhi, India. 2012

Book Chapters PublishedKrizaj D. Calcium Stores and Photoreceptor Function. In: Calcium Signaling, Advances in Experimental Medicine and Biology vol. 740, Ed. Shahidul Islam, Springer Verlag, Berlin. Invited review. Adv Exp Med Biol 740: 873-889 PMID: 22453974.

Ryskamp DA and Krizaj D. Polymodal Sensory Integration in the Visual System. Proc. IJS, Ljubljana, Slovenia. 2012

Mamalis N, Fuller S. Toxic Anterior Segment Syndrome. In Amar Agarwal, Athlyn Agarwal, Soosan Jacob (Eds.), Phacoemulsification (4th Edition, 38, pp. 137-145). New Dehli, India: Jaypee-Highlights. 2012

Vitale AT, Yang P. How Do I Differentiate Uveitis from Endophthalmitis? In Foster CS, Hinkle D& Opremcak EM (ed.), Curbside Consultation in Uveitis:49 Clinical Questions (Chapter 48). Slack Incorporated, New Jersey. 2012

Fo

cu

s 2

013

72

Fo

cu

s 2

013

73

R E S E A R C H G R A N T S

Balamurali K Ambati, MD, PhD, MBA

The Role of SFLT in Corneal Avascularity $338,625

National Eye InstituteDuration: 5/1/08–4/30/13

Intraceptor Interference of VEGF Pathways $278,187

National Eye InstituteDuration: 2/1/08–4/30/12

Subconjunctival Glaucoma Gel $35,000

University of Utah Research FoundationDuration: 12/1/11–11/30/12

Retinal Health Analyzer for Novel Therapy and Early Diagnostics for AMD $20,000

carl marshall & mildred almen Reeves FoundationDuration: 12/1/12–8/31/13

Endo-contact Lens for Corneal Protection in Cataract Surgery $35,000

University of Utah Research FoundationDuration: 6/1/12–5/31/13

Endoshield: Making Cataract Surgery Safer and Easier $40,000

Utah Governor’s Office ofeconomic Development Duration: 5/1/12–5/31/13

Pre-mRNA Interference of VEGF. VAMerit Award $650,000

VA Medical Center/Salt Lake City(US Veteran’s Administration)Duration: 10/01/09–9/13/13

Physician-scientist Award $60,000

Research to Prevent Blindness, Inc.Duration: 1/1/09–12/31/12

Intraceptor $1,498,040

NIH National Eye InstituteDuration: 5/1/08–4/30/12

Intraceptor Interference of VEGF inCorneal Angiogenesis. 5R01EY017182-02 $250,000

National Eye InstituteDuration: 4/1/07–3/31/12

Alessandra Angelucci, MD, PhD

V1 to V2 Pathways $372,488

National Institutes of HealthDuration: 8/1/09–7/31/12

Contextual Effects in V1 $120,000

National Science FoundationDuration: 3/1/09–2/29/12

Connectomics-feedback Circuits $28,000

University of Utah Research FoundationDuration: 1/1/12–12/31/12

A Novel Approach for Mapping Single-cell Long-range Connectionsin the Cerebral Cortex $298,916

National Institutes of HealthDuration: 5/1/12–7/31/14

Wolfgang B Baehr, PhD

Core Vision Research Grant (Baehr & Bernstein) $171,493

National Institutes of HealthDuration: 7/1/10–6/30/15

Membrane Protein Trafficking $335,239

National Institutes of HealthDuration: 12/1/08–11/30/13

Photoreceptor Ciliopathies: RP2, KIF17,and NPHP5 $373,750

National Institutes of HealthDuration: 5/1/12–4/30/16

The Role of Nephrocystin-5 in Retinal Degeneration $33,695

National Institutes of HealthDuration: 8/1/12–7/31/14

Study of Retinal Degeneration $57,000

Foundation Fighting BlindnessDuration: 8/1/10–7/31/13

The Function of ANKMY2 $90,500

International Retinal Research FoundationDuration: 10/7/11–11/7/12

Paul S Bernstein, MD, PhD

Biochemistry & Pharmacology of Macular Cartenoids $372,488

National Institutes of HealthDuration: 7/1/07–4/30/12

Macular Disorders $80,000

Macula Vision Research FoundationDuration: 12/16/09–12/15/12

Mactel Macular Carotenoids $147,600

Lowy Medical Research InstituteDuration: 11/1/10–10/31/12

Biochemical Studies in Support of the Next Generation AREDS Supplement for AMD $20,000

carl marshall & mildred almen Reeves FoundationDuration: 12/1/12–8/31/13

Research Grants and Contracts

J o H N A . M o R A N E y E C E N T E R

2012-2013Paul S Bernstein, MD, PhD

Bam114341 $234,887

GlaxosmithklineDuration: 05/01/11–12/31/14

Age-related Eye Disease (AREDS) Study II $168,000

EMMES Corporation/National Eye InstituteDuration: 06/01/06–Present

Biochemistry and Pharmacology of the Macular Cartenoids R01 EY 11600 $1,250,000

National Institutes of HealthDuration: 7/1/07–6/30/12

A Phase II/III Study of Encapsulated HumanNTC-201 Cell Implants Releasing Ciliary Neurotropic Factor (CNTF) for Participants with Retinitis Pigmentosa Using Visual Acuity as the Primary Outcome $114,820

Neurotech USA, Inc.Duration: 9/28/07–Present

NEER-CTEC For Vision Research $302,582

Foundation Fighting BlindnessDuration: 3/1/09–2/28/12

Macular Disorders $240,000

Macular Vision Research FoundationDuration: 8/1/09–12/15/12

Foreseehome Device $66,568

Emmes CorporationDuration: 06/1/10–12/31/12

Vpa Protocol $628,276

National Neurovision Research InstituteDuration: 06/1/10–1/31/13

Macular Pigment Carotenoids $179,500

Lowy Medical Research InstituteDuration: 12/1/10–11/30/12

Bam114341 $234,887

GlaxosmithklineDuration: 5/1/11–12/31/14

Opera $3,109

Emmes CorporationDuration: 10/1/11–9/30/12

MacTel Genetics Study $66,506

Lowy Medical Research Institute, Ltd.Duration: 5/1/89–12/31/12

AREDS 2 $149,081

Emmes CorporationDuration: 1/1/06–12/31/12

Alan S Crandall, MD

Oms302-Ilr-004 $48,270

Omeros CorporationDuration: 4/12/12–6/30/13

Oms302-Ilr-003 $21,467

Omeros CorporationDuration: 9/1/11–12/31/12

Cypass Glaucoma Implant $110,289

Transcend Medical, Inc.Duration: 1/1/11–12/31/14

Margaret DeAngelis, PhD

Identifying Underlying Mechanisms of Age-related Macular Degeneration $250,000

Edward N & Della L Thome MemorialDuration: 7/1/10–12/14/12

Identifying Underlying Mechanisms of Age-related Macular Degeneration for the Development of Appropriate Preventive and Therapeutic Interventions $681,816

Edward N & Della L Thome Memorial FoundationDuration: 12/15/09–12/14/12

Research to Understand the Genetic Epidemiology of Blinding Diseases of the Posterior Eye among Federally Recognized Native Americans $963,100

ALSAM FoundationDuration: 3/16/12–12/31/13

To Continue to Build a Repository of HumanEyes from the Utah Lions Eye Bank for Tissue Including the Isolation of Human Choroidal Endothelial Cells for Studies of Age-related Macular Degeneration for the Purpose of Gene Expression Assays and Functional Studies by the DeAngelis and Hartnett Laboratories $20,000

Principal Investigators: Margaret DeAngelis, Mary Elizabeth Hartnettcarl marshall reeves & mildred almen reeves Foundation, Inc.Duration: 12/1/12–8/31/13

Genetic Study of the Utah and Iowa Cohorts for Age-related Macular Degeneration $7,000

Educational Resource Development CouncilDuration: 5/1/11–5/31/12

Genetic Epidemiology Of AMD $94,310

Brigham and Women’s HospitalDuration: 9/1/10–8/31/12

Sibling Study of Age-related MacularDegeneration R01 EY-014458 $1,000,000

National Institutes of HealthDuration: 1/1/09–12/31/12

Kathleen B Digre, MD

Utah Women’s Health Information Network $500,000

Utah Department of Health Duration: 9/1/07–Present

Pairing Local Libraries with Local Health Centers $25,000

Department of Health and Human Services Duration: 1/1/08– Present

Gender-based Research na

Office on Women’s Health, Department of Health and Human Services Duration: 9/1/11–8/31/16

Coalition Healthier Community $465,701

National Cancer InstituteDuration: 9/1/11–08/31/16

Fo

cu

s 2

013

74

Fo

cu

s 2

013

75

Kathleen B Digre, PhD

Women’s Health Conference $1,811

DHHS Office on Women’s Health Duration: 12/2/11–9/14/12

Heart Campaign for Women $10,000

DHHS Office on Women’s Health Duration: 12/12/11–9/14/12

National Women’s Health Week 2012 $2,500

DHHS Office on Women’s Health Duration: 1/1/12–6/30/12

Nordic Iihtt $147,365

St. Lukes-Roosevelt Hospital Center Duration: 10/1/09–1/31/12

yingbin Fu, PhD

Cone Opsins in Photoreceptor Degeneration $373,541

National Institutes of Health Duration: 9/30/12–8/31/17

RPB Career Development Award $200,000

Research to Prevent Blindness Duration: 7/1/08–6/30/12

Strategies-Leber Congenital Amaurosis $240,000

E Matilda Ziegler Foundation Duration: 7/1/11–6/30/14

Leber Congenital Amaurosis $40,000

Knights Templar Eye Foundation Duration: 7/1/11–6/30/12

Development of Effective Therapies for Leber Congenital Amaurosis $60,000

Knights Templar Eye Foundation Duration: 7/1/12–6/30/13

A New Treatment Strategy for Age-related Macular Degeneration $20,000

Carl Marshall & Mildred Almen Reeves Foundation Duration: 12/1/2012– 8/31/2013

Sabine Fuhrmann, PhD

Mechanisms Controlling RPE Development $376,250

National Institutes of Health Duration: 1/1/10–12/31/13

Jason Goldsmith, MD

Communication about Glaucoma $54,551

University of North Carolina at Chapel Hill Duration: 3/1/11–4/30/13

Communication about Glaucoma and Patient Outcomes $91,426

National Institutes of Health Duration: 2/1/11–Present

Gregory S Hageman, PhD

DEC Complement MOD Therapy $2,986,452

National Institutes of Health Duration: 9/1/09–7/31/12

Genetic Susceptibility to Age-related Macular Degeneration $55,963

Columbia University Duration: 9/1/10–8/31/13

Hyperspectral Imaging of the Normal and Age-related Macular Degeneration $37,243

New York University Duration: 4/1/11–3/31/13

Research to Prevent Blindness Senior Scientific Investigator Award $150,000

Research to Prevent Blindness, Inc. Duration: 1/1/12–12/31/12

Improved Characterization of High-risk Phenotypes in Early AMD, Employing Novel Imaging and Functional Modalities $400,000

Macular Degeneration Foundation of Australia Duration: 10/4/11–10/4/14

Investigations of AMD in Africa $25,000

American Macular Degeneration Foundation Duration: 7/28/11–07/28/12

Alcon Recognition Award $200,000

Alcon Laboratories, Inc. Duration: 1/1/10–12/31/12

Development of Complement Modulating Therapeutics for Age-related Macular Degeneration: 1-R24-EY017404 $12,837,275

National Institutes of Health Duration: 8/1/06–7/31/12

Mary Elizabeth Hartnett, MD

Mechanisms of Angiogenesis in ROP $438,909

National Institutes of Health Duration: 7/1/10–6/30/14

Endothelial Transmigration in Neovascular Age-related Macular Degeneration $373,7505

National Institutes of Health Duration: 4/1/12–3/31/17

Diabetic Retinopathy Clinical Research Network NA

National Institutes of Health Duration: 1/1/11–Present

3R01 EY017011 03S1- Endothelial Transmigration in Neovascular Age-related Macular Degeneration, Instrument Supplement $500,000

National Institutes of Health Duration: 1/1/09–11/1/12

Endothelial Transmigration in Neovascular Age-related Macular Degeneration 3R01 EY01 $373,750

National Eye Institute Duration: 1/1/07–2/29/17

Studies on Angiogenic Mechanisms and Saftey Regarding Erythroprotein in Retinopathy of Prematurity: Seeking a Safe Treatment $90,000

March of Dimes Utah Chapter Duration: 2012–2015

Bryan W Jones, PhD

Normal Aging vs. Late Stage AMD Phenotypes $250,000

Edward N & Della L Thome Memorial Duration: 12/15/09–9/14/13

Retinal Circuits $827,185

Principal Investigators: Bryan W Jones, Robert E Marc

National Institutes of Health Duration: 12/1/11–11/30/16

Retinal Remodeling $440,990

Principal Investigators: Bryan W Jones, Robert E Marc

National Institutes of Health Duration: 12/1/03–3/31/16

Bradley J Katz, MD, PhD

Blast Ocular Injury $718,099

Principal Investigators: Brittany Coats, Yingbin Fu, Jason A Goldsmith, Bradley J Katz Kenneth L Monson

Army Medical Research Acquisition Activity Duration: 9/1/12–8/31/16

Quark 007 $93,635

Quark Pharmaceuticals, Inc. Duration: 9/1/12–8/31/16

David Krizaj, PhD

Regulation of Neurotransmission in the Retina $321,829

National Eye Institute Duration: 9/1/07–8/31/13

Core Vision Research Grant $85,254

National Institutes of Health Duration: 7/1/10–6/30/15

Role of Mechanosensation in the Retina $249,652

Nation Institutes of Health Duration: 12/1/12–11/30/16

Characterization of Molecular Mechanisms of Ocular Blast Trauma $269,406

Army Medical Research Acquisition Activity Duration: 8/15/12–8/14/2016

Retinal Inflammation and Degeneration are Modulated by TRPC Channels in Retinal Muller Glia $40,000

Knights Templar Eye Foundation Duration: 7/1/11–6/30/12

Pressure Transduction and Neuroprotection in Glaucoma $18,500

University of Utah Research Foundation Duration: 7/1/12–6/30/13

Novel TRPV4 Antagonist Prodrug for Treatment of Glaucoma $10,000

University of Utah Technology Commercialization Duration: 2012-2013

The Role of Very Long Chain Polyunsaturated Acids (VLC-PUFAs) in Dominant Stargardt Disease (STGD3) and Dry Age-related Macular Degeneration, TA-NMT-0810-0502-UUT $195,000

Principle Investigators: David Krizaj, Paul S Bernstein Foundation Fighting Blindness

Duration: 8/1/10–7/31/13

Edward M Levine, PhD

CCX10 Embryonic Retinal Cells $344,178

National Institutes of Health Duration: 12/1/08–11/30/12

Core Vision Research Grant $112,354

National Institutes of Health Duration: 7/1/10–6/30/15

Development & Evaluation of Mouse Models for Treating Retinal-related Pathologies $28,000

University of Utah Research Foundation Duration: 7/1/11–6/30/12

Nick Mamalis, MD

Power Adjustment and Biocompatibility, Amend #21 NA

Principal Investigators: Nick Mamalis, Liliana Werner

Calhoun Vision Inc. Duration: 5/5/07–4/30/12

Assessment of Capsular Bag Opacification after Implantation of Piggy Back IOL’s and a Dual-optic IOL NA

Principal Investigators: Nick Mamalis, Liliana Werner

Visiogen Inc. Duration: 1/1/05–Present

Evaluation of Removal of Lens Epithelial Cells in a Pig Eye NA

Alcon Research Ltd. Duration: 1/1/05–Present

AquaLase for Removal of Residual Lens Epithelial Cells During Cataract Extraction NA

Alcon Research Ltd. Duration: 3/1/05–Present

Gross and Histopathologic Evaluation of Explanted Rabbit Eyes that had been Implanted with a New Intraocular Lens NA

Principal Investigators: Nick Mamalis, Liliana Werner

Advanced Medical Optics Duration: 3/1/05–Present

Evaluation of EpiLoop to Remove Lens Epithelial Cells in Human Cadaver Eyes NA

Principal Investigators: Nick Mamalis, Liliana Werner

Phaco Treat Duration: 2/2/06–Present

Evaluation of the Power Adjustment and Biocompatibility of the Light Adjustable Lens in a Rabbit Model NA

Principal Investigators: Nick Mamalis, Liliana Werner

Calhoun Vision, Inc. Duration: 3/1/06–Present

Fo

cu

s 2

013

76

Fo

cu

s 2

013

77

Mark D Mifflin, MD

CPTS $51,800

Jaeb Center for Health Research Duration: 7/1/12–6/30/17

CPTS $109,350

Jaeb Center for Health Research Duration: 03/1/12–6/30/17

Evaluation of Topical Antibiotics/Risk of Endophthalmitis with Intravitreal Injection $20,000

Allergan, Inc. Duration: 1/1/09–Present

Cornea Donor Study: National Multicenter Investigation to Study the Effect of Age on Cornea Transplant Outcome $27,134

National Eye Institute Duration: 8/1/99–7/31/13

Robert E Marc, PhD

Structural Neurochemistry of Retinal Circuits $614,251

National Eye Institute Duration: 12/1/11–11/30/16

Retinal Remodeling $627,106

National Eye Institute Duration: 4/1/12–3/31/13

Core Vision Research Grant $166,840

National Eye Institute Duration: 7/1/10–6/30/15

Core Vision Research Grant (Main) $41,974

National Eye Institute Duration: 7/1/10–6/30/15

Core Vision Research Grant (Supplement) $300,000

National Eye Institute Duration: 7/1/12–6/30/13

Challenges in Imaging (ARRA) UCSB Subcontract $89,932

National Science Foundation Duration: 10/1/09–9/30/13

Retinoic Acid Plasticity $35,000

International Retinal Research Foundation Duration: 7/1/11–6/30/12

Normal Aging vs Late-stage AMD $691,825

Principal Investigators: Gregory S Hageman, Bryan W Jones, Robert E Marc

Edward N & Della L Thome Memorial Foundation Duration: 12/15/09–12/14/12

Retinal Remodeling $874,688

National Eye Institute Duration: 12/01/08–11/30/13

Retinal Circuits $1,569,456

National Institutes of Health Duration: 3/1/93–12/31/12

Majid Moshirfar, MD

ACOS Kxl-001 NA

Avedro, Inc. Duration: 9/1/12–6/30/13

IMT $71,090

VisionCare Ophthalmic Technologies, Inc. Duration: 12/2/11–12/31/16

Richard A Normann, PhD

Control of Efferent and Afferent Peripheral Nerve Activity with Intrafascicular Microstimulation $198,458

National Science Foundation Duration: 9/1/11–8/31/13

Randall J olson, MD

A Prospective Multi-centered Study of AcrySof Glistenings $25,000

Advanced Medical Optics, Inc. Duration: 6/1/08–Present

Assessing Post-occlusion Surge in Vacuum Flow Systems $10,000

Bausch & Lomb Duration: 05/1/08–Present

Visualizing MRSA Response to BAK +/- Gatifloxacin $8,000

Allergan, Inc. Duration: 5/1/08–Present

An Eyebank Comparison of Corneal Endothelial Damage with Dispersive OVDs $6,000

Advanced Medical Optics, Inc. Duration: 4/1/08–Present

Recovery of Bacteria from Intraocular Injection in Cadaver Eyes $25,000

Allergan, Inc. Duration: 8/1/07–Present

Differentiating the Effect of BAK and 4th Generation Fluoroquinolones against MRSA $12,000

Allergan, Inc. Duration: 4/1/07–Present

Michael P Teske, MD

The Natural History of Geographic Atrophy Progression (GAP) Study $75,900

Alcon Research Ltd Duration: 1/31/08–Present

GATE $312,860

Alcon Research Ltd Duration: 4/15/09–6/30/12

A Randomized, Double-masked, Active Controlled Phase III Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal VEGF Trap in Subjects with Neovascular Age-related Macular Degeneration Clinical Evaluation of Anti-angiogenesis in the Retina–Intravitreal Trial 3 (CLEAR-IT 3) NA

Regeneron Pharmaceuticals, Inc. Duration: 4/1/07–Present

A Phase 2, Randomized, Double-masked, Placebo-controlled, Dose-ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injections of Sirolimus in Patients with Diabetic Macular Edema Secondary to Diabetic Retinopathy NA

Sub investigator Macusight, Inc. Duration: 10/14/08–Present

Northern California Section of the Collaborative Ocular Melanoma Study NA

National Eye Institute Duration: 1/1/87–Present

Ning Tian, PhD

Development of Synaptic Pathways $374,375 in Retina

National Institutes of Health Duration: 4/1/11–3/31/16

Development of Synaptic Pathways in Retina (Supplement) $263,900

National Institutes of Health Duration: 4/1/12–3/31/13

Monica Vetter, PhD

1 R21 EY019390 Retina-derived Signals Regulating Development of the Vitreous Hyaloid Vasculature $413,771

National Institutes of Health, NEI Duration: 7/1/09–6/30/12

Catalyst for a Cure $1,101,250

Glaucoma Research Foundation Duration: 1/1/10–12/31/12

2 R01 EY012274 Regulation of Retinal Neurogenesis by bHLH Factors $2,740,163

National Institutes of Health Duration: 7/1/08–6/30/13

1 R01 EY020878 Role of Microglia in Experimental Glaucoma $984,465

National Institutes of Health Duration: 7/1/10–6/30/15

Albert T Vitale, MD

A Phase 2, Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Injections of E10030 (Anti-PDGF Pegylated Aptamer) Given in Combination with Lucentis in Subjects with Neovascular Age-related Macular Degeneration NA

Sub-Investigator Ophthotech Corporation Duration: 8/17/10–Present

The Safety and Efficacy of AL-8309B Ophthalmic Solution for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration NA

Sub-Investigator Alcon Research Ltd Duration: 8/18/09–Present

Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants with Retinitis Pigmentosa Using Visual Acuity as Primary Outcome NA

Neurotech USA, Inc. Duration: 4/1/07–Present

Multicenter Uveitis Steroid Treatment (MUST) Trial $281,000

Johns Hopkins University Neuro-education Initiative Duration: 12/1/05–Present

Genetic Epidemiology $963,100

Principal Investigators: Paul S Bernstein, Margaret DeAngelis, Mary Elizabeth Hartnett, Albert T Vitale

ALSAM Foundation Duration: 3/16/12–12/31/13

A Phase 2, Multi-center, Randomized, Double-masked, Placebo-controlled, Parallel-group Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of GSK933776 in Adult Patients with Geographic Atrophy Secondary to Age-related Macular Degeneration NA

Sub-Investigator Glaxosmithkline Duration: 9/21/11–Present

MUST Follow-up Study $7,731

Johns Hopkins University Duration: 5/1/12–4/30/13

C-10-034 Durazol Uveitis $32,733

Alcon Research Ltd Duration: 12/1/10–12/31/12

Adalimumab M10-880 $93,537

Abbott Laboratories Duration: 7/1/10–12/31/12

Adalimumab M10-877 $95,771

Abbott Laboratories Duration: 7/1/10–12/31/12

Fo

cu

s 2

013

78

Fo

cu

s 2

013

79

Albert T Vitale, MD

Adalimumab M11-327 $63,014

Abbott LaboratoriesDuration: 7/1/10–12/31/12

Double-mass, Placebo-controlled, Multi-centered, Dose-ranging Study to Assess the Efficacy and Safety of LX211 as Therapy Clinically Quiescent Sight-threatening, Non-infectious Uveitis na

Lux Biosciences, Inc.Duration: 4/1/07–Present

Comparison of AMD Treatment Trial (CATT)–Lucentis–Avastin Trial na

Emmes Corporation/National Eye InstituteDuration: 4/1/07–Present

A Phase III Study of the Efficacy and Safety of RhufabV2 (Ranibizumab) In Subjects with Minimally Classic or Occult Subfoveal Neovascular Age-related Macular Degeneration (MARINA) na

Sub-Investigator Unmasked Treating Physician Genentech Inc.Duration: 3/1/03–Present

Phase II Clinical Trial: A Multicenter Randomized Double-masked Controlled Study to Evaluate the Safety and Efficacy of an Intravitreal Fluocinolone Acetonide (0.5 or 2 mg) Implant in Patients with Noninfectious Uveitis Affecting the Posterior Segment of the Eye, American Study na

Bausch & LombDuration: 1/1/03–Present

A Multicenter, Randomized Controlled Study to Evaluate the Safety and Efficacy of an Intravitreal Flucinolone Acetonide (0.5mg)Implant Compared to Standard Therapy in Patients with Non-infectious Uveitis Affecting the Posterior Segment of the Eye na

Co-InvestigatorBausch & LombDuration: 4/1/02–Present

Judith E A Warner, MD

A Multicenter, Double-blind, Randomized, Placebo-controlled Study of Weight- reduction and/or Low-sodium Diet Plus Acetazolamidevs Diet plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss Neuro- Ophthalmology Research Disease $80,500

Sub Investigator Investigator ConsortiumDuration: 11/30/09–11/30/15

Liliana Werner, MD, PhD

Evaluation of a New IOL $8,529

Principal Investigators: Nick Mamalis, Liliana Werner

PhysIOLDuration: 11/1/12–4/30/13

Evaluation of a New IOL $66,537

Principal Investigators: Nick Mamalis, Liliana Werner

Abbott Medical OpticsDuration: 2/10/12–1/31/13

New Intraocular Lens Material $20,374

Principal Investigators: Nick Mamalis, Liliana Werner

Innovia LLCDuration: 9/19/11–7/31/12Duration: 9/19/11–7/31/12Duration: 9/19/11–

Evaluation of a New IOL $10,986

Principal Investigators: Nick Mamalis, Liliana Werner

Advanced Vision Science, Inc.Duration: 10/1/10–9/30/13

Evaluation of a New IOL $43,323

Principal Investigators: Nick Mamalis, Liliana Werner

Anew Optics, Inc.Duration: 5/1/10–4/30/13

Silicone Oil in the Eye $201,211

Principal Investigators: Nick Mamalis, Liliana Werner

PowerVision, Inc.Duration: 3/30/09–Present

Evaluation of a Dual-optic IOL $48,650

Principal Investigators: Nick Mamalis, Liliana Werner

Visiogen, Inc.Duration: 1/15/09–12/15/12

Jun yang, PhD

Formation and New Components of the Usher 2 Placebo-controlled study of Weight-reduction and/or Low-sodium Diet Plus Acetazolamide vs Diet plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss Neuro-ophthalmology Research Disease $336,937

National Institutes of HealthDuration: 4/1/11–3/31/16

Formation and Function(s) of the Usher 2 Protein Complex in Photorecptors $80,000

E Matilda Ziegler FoundationDuration: 1/1/11–12/31/13

Gene Therapy for Retinitis Pigmentosain Usher Syndrome Type 2 $50,000

Foundation Fighting BlindnessDuration: 8/1/10–7/31/13

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Alessandra Angelucci, MD, PhD Invited Speaker Seminar, Circuits for Spatial Salt Lake City, UT 2002–presentIntegration of Information in the Primate Visual Cerebral Cortex. Math Biology Seminar Series, Department of Mathematics

Invited Speaker Seminar, Rewiring the Brain: Role of England 1998–presentAfferents and Targets in the Generation of Specific and Patterned Connections. Departmental Lecture, University Laboratory of Physiology, Oxford University

Honorary Lectureship, Department of Optometry Manchester, England 2001–presentand Neuroscience, UMIST

Seminar, The Spatial Logic of Intra-areal and Inter- Chicago, IL 1999–presentareal Connections within and between Areas V1, V2, V3, and V5/MT of the Macaque Visual Cortex. Computational Neuroscience Seminar Series, Department of Mathematics, University of Chicago

Invited Speaker Seminar, Rewiring the Brain: Role of Pisa, Italy 1998–presentAfferents and Targets in the Generation of Specific and Patterned Connections. Department of Physiology, Consiglio Nazionale delle Ricerche

Wolfgang B Baehr, PhD Membrane Protein Transport in Photoreceptors. Salt Lake City, UT 2012Department of Biochemistry, University of Utah

Organizer of 14th Vision Research Conference Ft. Lauderdale, FL 2012Retina Ciliopathies: From Genes to Mechanisms and treatment

The Function of PDE6D and UNC119 in Photoreceptors Berlin, Germany 2012

Membrane Protein Transport in Photoreceptors. Nashville, TN 2012Vanderbuilt

Membrane Protein Transport in Photoreceptors. Muenchen, Germany 2012MPI for Biochemistry

Paul S Bernstein, MD, PhD Invited Speaker and Moderator, International Symposium Rome, Italy 2010–presenton Ocular Pharmacology and Therapeutics

Invited Speaker and Panelist, Hohenheim Stuttgart, Germany 2008–presentconsensus conference

Invited Speaker, to Educate Russian Ophthalmologists Saint Petersburg 2010–presenton the Value of Nutritional Supplements for Age- and Moscow, Russia related Macular Degeneration

Invited Speaker, Royal Ophthalmological Society, Elizabeth Nottingham, England 2010–presentThomas Age-related Macular Degeneration Symposium

Invited Speaker, Retina Sub-specialty Day, San Francisco, CA 2012american academy of ophthalmology

Invited Lecturer, Ophthalmic Photographers Society San Francisco, CA 2012

Invited Speaker, Bascom Palmer Eye Institute Miami, FL 2009–present

Invited Speaker, Florida International University Miami, FL 2010–present

This is a partial list of Moran National and International Presentations

Fo

cu

s 2

013

80

Fo

cu

s 2

013

81

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Invited Speaker, American Optometric Association Orlando, FL 2010–present

Invited Lecturer, Ophthalmic Photographers Society Chicago, IL 2011–present

Alan S Crandall, MD Management of Cataract in Challenging Cases. Milan, Italy 2012Malpositioned Lenses: Techniques for Surgical Management. Finer Points in IOL Fixation: New Techniques, New Instrumentation. Management of Co-existing Cataract and Glaucoma: Surgical Challenges. Non-penetrating Glaucoma Surgery and Canaloplasty for New Glaucoma Surgeons. overview of Suprachoroidal Devices. The Surgical Management of Lens Exchange and the Malpositioned IOL. The XXX Congress of the European Society of Cataract & Refractive Surgeons

New Surgical Procedures. Managing Late Subluxation. Santiago, Chile 2012Pseudoexfoliation (Including Use of Capsular Devices). ltrachopper and managing Hard cataracts. managing Combined Glaucoma and Cataract (Trabeculectomy, Express Shunts and Canaloplasty). Express Shunt GlaucomaFiltration Lab. Seventh International Ophthalmology Symposium, University of Chile

Surgical Management of Subluxated Crystalline and Chicago, IL 2012Intraocular Lenses. Management of Difficult Cataracts and Challenging Situations. Finer Points in IOL Fixation: New Techniques, New Instrumentation. Toxic Anterior Segment Syndrome Following Cataract Surgery. Tackling Weak Zonules and Using Capsular Tension Devices. Fixing the Iris: Strategies and Surgical Techniques. Coexisting Cataract and Glaucoma: Tips for the Uneasy Relationship. International Prechop Symposium. Intraocular Lens Exchange and Repositioning Techniques. Risk Factors of Cataract Surgery in PXF. 2-H Intraocular Surgery: Challenging Cases. American Society of Cataract and Refractive Surgery

IOL Exchange. Spotlight on Cataracts: Clinical Decision- Chicago, IL 2012making With Cataract Complications. Advanced Refractive Cataract Surgery and Anterior Segment Reconstruction. Schlemm canal Surgery. the Surgical management of the Malpositioned IOL. Cataract Surgery in the Setting of Ocular Comorbidities and High-risk Features for Intraoperative and Postoperative Complications. One-stop Chop Squad. American Academy of Ophthalmology

Clinical Decisions in the Management of Complications New York, NY 2012of Cataract and IOL Surgery. Arbisser LB, Crandall AS, Hoffer J, Rowen S, Tabin GC, Gills JP, Michelson MA,Nichamin LD, et al. American Academy of Ophthalmology

Invited Speaker, The Role of Adjunctive Testing in Orlando, FL 2012Monitoring Glaucoma. Nuclear Disassembly Technique Including Femtosecond Laser and Nucleus Chopper. Glaucoma Surgery: New Variations and Techniques. Advanced Uses of Capsule Support System Introperatively. Masters in Ophthalmology 2012

Merging Complex Anterior Segment Surgery and Glaucoma: New York, NY 2012Why the Glaucoma Specialist Should Be the Best Surgeon in the Group. american Glaucoma Society 22nd Annual Meeting

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

Moderator, New Horizons in Glaucoma Devices. San Francisco, CA 2012–presentGlaucoma 360 - New Horizons Forum

Complex Cataract Cases and Management of Patients Philadelphia, PA 2012–presentwith Subluxed IOLs. Advanced Anterior SegmentUpdate, Wills Eye Institute

Staged Procedures, Surgery. World Ophthalmology Abu Dhabi, United Arab 2012Congress. The XXX111 International Congress Emiratesof ophthalmology

Malpositioned Lenses - Techniques of Surgical Vienna, Austria 2012Management. Course: IC-14 Management of Co-existingCataract and Glaucoma: Surgical Challenges. The Future of Cataract Surgery: Experience and Results. European Society of Cataract and Refractive Surgery

The ABCs of CTRs. Hard Lenses with Loose Zonules Playa del Carmen, 2012in PXE Case Presentation. Winter Update 2010, American MexicoSociety of Cataract and Refractive Surgery

Donnell J Creel, PhD Invited Speaker, Visually Evoked Potentials. International Kathmandu, Nepal 2012Retina and Glaucoma Conference. Tilganga Institute of ophthalmology

Invited Speaker, Visually Evoked Potentials. Chengdu, China 2012Electroretinograms. West China Hospital

Margaret DeAngelis, PhD Genomic Convergent Approach Provides Evidence Boston, MA 2012for a Role of CVD and Lipids in Age-related Macular Degeneration. The AMD Symposium, Harvard Medical School, Schepens Eye Institute

The Genetics of Age-related Macular Degeneration: Boston, MA 2003–presentAn Overview. The AMD Symposium, Massachusetts Eye & Ear Infirmary

Curing Age-related Macular Degeneration in our Lifetime. Salt Lake City, UT 2012Foundation Fighting Blindness Conference.

Genomic Convergent Approach to Characterizing Belfast, Ireland 2012Pathways/Mechanisms Underlying Age-related Macular Degeneration. Ninth Alumni and Research Day Meeting, Queen’s University

Nuclear Receptors as Druggable Targets for Age-related Berlin, Germany 2012Macular Degeneration. International Society for eye research

Kathleen B Digre, MD Idiopathic Intracranial Hypertension: Current Concepts. College Park, MD 2012University of maryland

Caring for Two: Neuro-ophthalmic Disorders in Dallas, TX 2012Pregnancy. The Carol Zimmerman Lecture, University of texas Southwestern texas Southwestern t

Photophobia in Blepharospasm. Dystonia Chicago, IL 2012Coalition Meeting

Episodic to Chronic Migraine and Back Again. Scottsdale, AZ 2012Digre KB, Schwedt TJ. American Headache Society

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Fo

cu

s 2

013

82

Fo

cu

s 2

013

83

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Oral Contraceptives and Migraine. American Scottsdale, AZ 2012Headache Society

Common Important Neuro-ophthalmoscopic Findings. New Orleans, LA 2012american academy of neurology

Neuro-ophthalmology. All-day Course, American New Orleans, LA 2012academy of neurology.

Moderator: Treatment. Digre KB, Dodick DW, Scottsdale, AZ 2012Silverstein SD. American Headache Society, Scottsdale Headache Symposium

Gregory S Hageman, PhD Invited Speaker, Biology, Genetics, and Pathways Beijing, China 2012Associated with Age-related Macular Degeneration: a new era. challenge in amD Study

Invited Speaker and Award Recipient, The Pathogenesis New York City, NY 2012Genetics, Diagnosis, and Treatment of Age-related Macular Degeneration: Entering a New Era. Lighthouse International Pisart Vision Award

Keynote Lecture, Toward a Refined Understanding of the Boston, MA 2012Genetics, Biology, and Treatment of Age-related Macular Degeneration. Distinguished Lecture, Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary

Keynote Speaker, Toward a Refined Understanding Omaha, NE 2012of Age-related Macular Degeneration: A New Era. Gifford Lecturer, Gifford-Truhlsen Residents and Alumni Day, University of Nebraska Medical Center

Invited Speaker, Drusen-Harbingers of Age-related Paris, France 2012Macular Degeneration-associated Pathways and Genes.Macula of Paris

Invited Speaker, The Genetics of Non-exudative New York, NY 2012Age-related Macular Degeneration. Macula 2012, Atlantic Coast Retina Club

Invited Speaker, Diagnostics & Therapeutics for Newport Beach, CA 2012Age-related Macular Degeneration: A New Era. Fifth Annual FFB & Gavin Herbert Eye Institute Ophthalmic Innovations Symposium

Moderator, Invited Speaker. Genotype Correlation-Biology- Newport Beach, CA 2012Phenotype. Clinical-pathological Correlation in Patients with a History of Reticular Pseudodrusen. Arnold and Mabel Beckman Initiative for Macular Research

Invited Speaker, Toward a Refined Understanding Chicago, IL 2012of the Biology and Genetics of Age-related Macular Degeneration: Therapeutic & Diagnostic Implications. Eleventh Macular Vision Research Foundation Conference

Invited Speaker, An Integrated Hypothesis of the San Francisco, CA 2012Development and Progression of Age-related Macular Degeneration Based upon Available Genetic and Biological Data. Sixty-second Annual Meeting of the American Society of Human Genetics

Invited Speaker, Hope in Sight, John Moran Eye Center Sun Valley, ID 2012

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

Invited Speaker, Toward the Development of Diagnostcs Seoul, South Korea 2012and Therapeutics Targeting Age-related Macular Degeneration and Its Co-segregating Diseases: A New Era. Fifteenth Samsung Macula Symposium, Samsung Medical Center, Sungkyunkwan University School of medicine

Invited Speaker, Toward a Refined Understanding Washington, DC 2012of the Genetics and Biology of Age-related Macular Degeneration. National Eye Institute

Invited Speaker, A New Era: Diagnostics and Therapeutics - Washington, DC 2012Targeting Age-related Macular Degeneration and Its Co-segregating Diseases. Alliance for Eye and Vision Research’s Decade of Vision, 2010-2020 Initiative: a Congressional Briefing, House Rayburn, United States congress

Invited Speaker, Royal Victoria Hospital Belfast, Northern Ireland 2012

Invited Speaker, Unique Angiographic Characteristics Melbourne, Australia 2012Associated with Reticular Psuedodrusen. Fluorescein Conference, Centre for Eye Research Australia

Invited Speaker, Concepts Relating to the Biology of Irvine, CA 2012Age-related Macular Degeneration. Beckman Initiative for Macular Research

Mary Elizabeth Hartnett, MD Personal and Historical Insights into the Henrietta Ft. Lauderdale, FL 2012Lacks Story. The Small GTPase Rap1 Regulates Intracellular ROS Generation in RPE. Wang H, Wittchen E, Hartnett ME. The Association for Research in Vision and Ophthalmology

Retina Lecture: Vascular and Choroidal Disease Salt Lake City, UT 2012(non-diabetic) II. Diabetic Retinopathy. Retinopathy of Prematurity. Considerations Regarding Anti-VEGF Treatments in Severe Retinopathy of Prematurity. John A. Moran Eye Center, University of Utah

Mechanisms involved in Neovascular Age-related Augusta, GA 2012Macular Degeneration. Vision Discovery Institute Distinguished Seminar Series

Delayed Retinal Angiogenesis by VEGF-mediated San Francisco, CA 2012Downregulation of Erythropoltin. PediatricRetinal Vascular Meeting

The Small GTPase Rap1 Regulates Intracellular ROS Ft. Lauderdale, FL 2012Generation in RPE. The Association for Research in Vision and ophthalmology

Invited Speaker, Evidence for use of Avastin in ROP. Salt Lake City, UT 2012Neonatal/Perinatal Conference, University of Utah, Primary Childrens Medical Center

Robert o Hoffman, MD Visiting Professor Lecture, Retinoblastoma. Rapid City, SD 2012Black Hills Regional Eye Institute

Bryan W Jones, PhD Clinical Faculty Day, University of Utah Ophthalmology Salt Lake City, UT 2012

Invited Speaker, Neural Retina. International Berlin, Germany 2012Society for eye research

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Fo

cu

s 2

013

84

Fo

cu

s 2

013

85

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Moderator: International Society for Eye Research, Berlin, Germany 2012Retinal Remodeling Session XX Biennial Meeting

Bradley J Katz, MD, PhD Presentation: Treatment of Subjects with Giant Cell San Antonio, TX 2012Arteritis with Antibiotics. A Murine Model of Giant Cell Arteritis: Infection with a Burkholderia Pseudomallei-like Strain Treated with Steroids and Antibiotics. Annual Meetingof the North American Neuro-Ophthalmology Society

Keynote Presentation, From Watching to Seeing: Surabaya, Indonesia 2012Retinal Signaling and Polymodal Integration of Sensory Information. Fifteenth International Multiconference on Cognitive Sciences, Jozef Stefan Institute

Featured Speaker, Zion Bank’s “Speaking on Business,” Salt Lake City, UT 2012KSL and KUTV. The KSL piece was distributed nationally

David Krizaj, PhD Invited Speaker, Retinal Glia: Glue, Feeders, Protectors, Snowbird, UT 2012and Mischief Makers. Neurobiology and Glia Symposium

Keynote Presentation, From Watching to Seeing: Ljubljana, Slovenia 2012Retinal Signaling and Polymodal Integration of Sensory Information. Fifteenth International Multiconference on Cognitive Sciences, Jozef Stefan Institute

Platform Presentation, Trpv4 Channels Modulate Steamboat, CO 2012Neurons. Federation of American Societies forExperimental Biology, Summer Research Conference on Retinal Processing

Platform Presentation, Polymodal TRPV4 Signals in Berlin, Germany 2012Retinal Ganglion Neurons. International Society for eye research

Platform Presentation, Diverse Mechanisms Mediate Snowmass, CO 2012TRPV4’s Polymodal Responses. Presented by D. Ryskamp. Summer Research Conference on Calcium Signaling, Federation of American Societies for Experimental Biology

Research Presentation, The Roles, Properties, and Ashburn, VA 2012Consequences of Mechanosensation in the Retina. Presented by D. Ryskamp. Janelia Farms

SIG Presentation, Mechanosensation, TRPV4 Signaling Ft. Lauderdale, FL 2012and Neurodegeneration in the Mammalian Retina. Annual Meeting of the Association for Research in Vision and ophthalmolog

Invited Seminar, TRPing the Retina: Role of Augusta, GA 2012Nonconventional Calcium Signals in Mechanosensation, Visual Behavior, and Disease. Georgia Health Sciences University

Nick Mamalis, MD Correction of Postoperative Refractive Surprises after Athens, Greece 2012Brunescent Cataract. Twenty-sixth International Congress of the Hellenic Society of Intraocular Implant and Refractive Surgery

The ASCRS/ESCRS Survey on Foldable IOLs Requiring Vienna, Austria 2012Explantation or Secondary Intervention, 2010 Update.Mamalis N, Fuller S, Kavoussi S, McIntyre J. Vienna. 2011 XXIX Congress of the European Society of Cataract and Refractive Surgeons

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Pathologic Comparison of Asymmetric or Sulcus Milan, Italy 2012Fixation of Three-piece Intraocular Lenses with SquareVersus Round Anterior Optic Edges. Mamalis N, Bodnar Z, Werner L, Leishman L, Ollerton A, Michelson J, Strenk S. Milan 2012 XXX Congress of the European Society of Cataract and Refractive Surgeons

Strategies and Techniques for IOL Exchange (A). Vienna, Austria 2012Tassignon MJ, Auffarth G, Mamalis N, Tetz M, Masket S

Cataract Surgery in Pseudoexfoliation Patients. Maui, HI 2012Hawaiian Eye 2012, Grand Wailea Resort

Toxic Anterior Segment Syndrome. Buffalo Buffalo, NY 2012Ophthalmology Symposium, Olmsted Center for Sight

Symposium/Moderator, Cataract. Controversies in Chicago, IL 2012in Cataract and Refractive Surgery. Correction of Refractive Surprises: Lens-based Versus Laser Correction. The ASCRS-ESCRS Survey of Foldable IOLs Requiring Explaintation or Secondary Intervention. Toxic Anterior Segment Syndrome: Update on Most Common Causes. Assessment of Single-piece Hydrophilic Acrylic and Silicone IOLs for Sulcus/Piggyback Fixation in Pseudophakic Cadaver Eyes. Evaluation of Capsular Bag Opacification With New Disc-shaped Hydrophilic Acrylic Foldable IOL in Rabbit Model. Pathological Assessment of Complications with Asymmetric or Sulcus Fixation of Square-edged Hydrophobic Acrylic IOLs. Pathological Comparison of Sulcus Fixation of 3-piece IOLs with Square or Round Anterior Optic Edges. Effective Communication Skills (Tips for Public Speaking/Writing. American Society of Cataract and Refractive Surgery

Risk Factors for Toxic Anterior Segment Syndrome, Chicago, IL 2012(Best Paper of Session). Pathologic Comparison of Asymmetric or Sulcus Fixation of 3-piece IOLs with Square vs. Round Anterior Optic Edges (Original Paper). Toxic anterior Segment Syndrome Following anterior Segment Surgery, Roundtable Moderator. Cataract Surgery in the Setting of Ocular Comorbidities and High-risk Features for Intraoperative and Postoperative Complications. Astigmatism in the Cataract Patient. IFIS: Clinical Update (Case 7 in Spotlight on Cataract: Clinical Decision-making with Cataract Complications. One-stop Chop Squad. ThePathology of Exfoiliation: Are the Canal and Collectors Affected? Spotlight on Pseudoexfoliation. Phacoemulsification and Advanced Techniques. American Academy of Ophthalmology/Asia Pacific Academy of ophthalmology

Majid Moshirfar, MD Ocular Surface Complications Associated with Acute Salt Lake City, UT 2012Blepharitis. ALCON Meeting

Dry Eye: A Disease that May Progress. ALLERGAN- Boise, ID 2012SCS-core Meeting

Dry Eye: A Disease that May Progress. ALLERGAN- Salt Lake City, UT 2012SCS-core Meeting

Fo

cu

s 2

013

86

Fo

cu

s 2

013

87

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Randall J olson, MD 2012 Binkhorst Lecturer, Where Are We on the Road Chicago, IL 2012to Optical Perfection? Symposium on Cataract, IOL, and Refractive Surgery. American Society of Cataract and Refractive Surgery

Talk Title: Cataract Surgery in the Face of a PKP. Chicago, IL 2003–presentCataract Surgery in the Setting of Ocular Comorbidities and High-risk Features for Intraoperative and Postoperative Complications. Annual Meeting, American Academy of ophthalmology

Senior Instructor, Advanced Phaco Labs. American Chicago, IL 2012Learning Phaco Chop. Latest on POE, Advanced Phacoemulsification Session. American Academy of ophthalmology

Session Moderator, White Lens + Uveitis. Eleventh Chicago, IL 2012Annual Spotlight on Cataract Symposium, American academy of ophthalmology

Intraocular Surgery, Surgical Techniques. Toxic Chicago, IL 2012anterior Segment Syndrome Following cataract Surgery. american Society of cataract and Refractive Surgery

Session Moderator, Advanced Phaco Skills. Senior Chicago, IL 2012Instructor, Learning Phaco Chop: Pearls and Pitfalls.American Society of Cataract and Refractive Surgery

Personal Experience with the Catalys System. Chicago, IL 2012Eyeworld Symposium, American Society of Cataract and Refractive Surgery

Presentation, Wound Burn: Causation and Prevention. Vail, CO 2012Twenty-ninth Annual Johns Hopkins Current Concepts in ophthalmology conference

Speaker, What We Know About PBK Prevention. Gainesville, FL 2012Fiftieth University of Florida Department of Ophthalmology Anniversary Meeting and Scientific Meeting, Hilton Conference Center, University of Florida

Speaker, Fundraising: Key to the Future. Innovation. Miami, FL 2012University Professors of Ophthalmology MeetingsCaucus on Translational Research. A Business Plan for Chair Tenure. Top Ten Management Problems. Association of University Professors of OphthalmologyMeeting

Speaker, Other Concerns Surrounding Intraoperative Maui, HI 2012Aberrometry. Hawaiian Eye Nursing Meeting

Speaker, Surgical Management of IFIS. Some Maui, HI 2012Concerns about Relying on Intraoperative Aberrometry. Non-surgical Means of Correcting Post-surgical Refractive Error. Hawaiian Eye Conference

Bhupendra C K Patel, MD, FRCS, FRC Cosmetic Surgery Forum. Facial Cosmetic Surgery Meeting Las Vegas, NV 2012

Jeff Pettey, MD Effective Communication during Patient Encounters. Salt Lake City, UT 2012Resident Lecture. John A. Moran Eye Center

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Geoffrey Tabin, MD International Opportunities for Young Ophthalmologists. Chicago, IL 2012Clinical Decisions in the Management of Complications of Cataract and IOL Surgery. Manual Extracapsular Cataract Extraction (ECCE/SICS). Surgery: Indications andTechniques. American Academy of Ophthalmology

Life Long Vision Foundation. The Eye Ball St. Louis, MO 2012

International Ophthalmology. Canadian Canada 2012ophthalmology Society

Impossible Dreams—The Ascent of Everest and Eradicating Salt Lake City, UT 2012World Blindness Program. The 33rd Annual Technical Staff Education.

Monica Vetter, PhD Genentech, Neuroscience Research Department Palo Alto, CA 2012

Harvard Medical School, Massachusetts Eye and Boston, MA 2012Ear Infirmary

Medical College of Wisconsin, Department of Milwaukee, WI 2012Cell Biology, Neurobiology & Anatomy

Gordon Research Conference on Visual System New London, NH 2012Development, Colby-Sawyer College

CSVT - Acute and Chronic Management and Concerns. Salt Lake City, UT 2012Stroke Conference, University of Utah

Albert T Vitale, MD Combined PPV and Phaco-IOL for Uveitis. Eighth Halkidiki, Greece 2012International Symposium of Uveitis (IUSG)

Invited Speaker: Is It Birdshot Retinochoroidopathy, Chicago, IL 2012and If So, How Should I Treat It? American Academy of Ophthalmology, Uveitis Sub-specialty Day

Panel Discussion: Uveitis Potpourri. American Academy Chicago, IL 2012of Ophthalmology, Uveitis Sub-specialty Day

Invited Speaker: Multimodal Imaging in Uveitis, and Orlando, FL 2012Diagnosis and Treatment of Uveitis. American Academy of ophthalmology

Invited Speaker: Diagnostic and Therapeutic Vitrectomy in San Francisco, CA 2012Uveitis. Cal Pacific

Poster Presentation: Macular Retinal Vasculitis Fort Lauderdale, FL. 2012and Choroiditis Associated with Wegener's Granulomatosis: Case Series. Vitale AT, Lim LT, Shelton J, Vasudevan V, Moorthy R. Association for Research in Vision and ophthalmology

Judith E A Warner, MD WINO Hot Topics in Neurology, NMO: What’s New? Salt Lake City, UT 2012

Neuro-ophthalmology Fall Festival Boston, MA 2012

NANOS: Hot Topics in Neuro-ophthalmology, Utah Artificial San Antonio, TX 2012Vision Project: Occipital Cortical Implants for Blindness

CSVT: Acute and Chronic Management and Concerns. Salt Lake City, UT 2012Stroke Conference, University of Utah

Fo

cu

s 2

013

88

P R E S E N T E R T o P I C o R T I T L E L o C A T I o N D A T E

N AT I o N A L A N D I N T E R N AT I o N A L P R E S E N TAT I o N S

Liliana Werner, MD, PhD Winter Update. american Society of cataract and Playa del Carmen, Mexico 2012and Refractive Surgery

Afonso Fatorelli Lecture, The XII International Congress São Paulo, Brazil 2012on Cataract and Refractive Surgery

The 26th Congress of the Deutschsprachige Berlin, Germany 2012Gesellschaft für Intraokularlinsen-Implantation und Refraktive Chirurgie (DGII)

Keynote Speaker, Annual Cataract Course Ayr, Scotland 2012

Barbara M Wirostko, MD Human Growth Hormone Delivery from PEA Fibers Dublin, Ireland 2012for the Treatment of Corneal Wounds. John Zupancich, Julien Bérard, Hecka A, Kemp A, Muller M, Mihov G, Reiver S, Messier K, Thies J, Wirostko B, Rafii MJ. Twenty-second Annual BioInterface Conference, University College

Human Growth Hormone Delivery from PEA Fibers New Orleans, LA 2012for the Treatment of Corneal Wounds. John Zupancich, Julien Bérard, Hecka A, Kemp A, Muller M, Mihov G, Reiver S, Messier K, Thies J, Wirostko B, Rafii MJ. Sixteenth Symposium on the material Science and Chemistry of Contact Lenses

Invited Speaker, Early-stage Startup Companies: Ft. Lauderdale, FL 2012Strategies for entrepreneurship in ophthalmology. ARVO Education Course

Safety and Efficacy of a Novel Topical Rho Kinase Ft. Lauderdale, FL 2012Inhibitor ATS8535 In Vivo. Wirostko B, Umeno H, Hsu H, Kengatharan M. Abstract #. 5079. Association for research in Vision and ophthalmology

Sustained Delivery for Glaucoma. March Meeting, New York, NY 2012american Glaucoma Society

Jun yang, PhDyang, PhDy Current Understanding of the Usher 2 Complex, Fort Lauderdale, FL 2012Retina Ciliopathies: From Genes to Mechanisms and Treatment. Elsevier: 14th Vision Research Conference

Podium Presentation, Whirlin Modulates the San Diego, CA 2012Actin-regulatory Function of Espin. Midwinter Meeting, Association for Research in Otolaryngology

Functional Exploration of the Usher Syndrome Type 2 Salt Lake City, UT 2012Complex. Membrane Trafficking Minisymposium, University of Utah

Marielle young, MDyoung, MDy Pediatric Ophthalmology, Association for the Education Salt Lake City, UT 2012and Rehabilitation of the Blind and Visually Impaired. Division of Services for the Blind and Visually Impaired

Timing of Surgery and Nystagmus in Patients with Salt Lake City, UT 2012Bilateral Infantile Cataracts. Clinical Faculty Day, John A. Moran Eye Center, University of Utah

Diagnosis and Management of Ocular Torsion Disorders. Salt Lake City, UT 2012Infantile Cataracts. North Star Optometry Seminar, John A. Moran Eye Center, University of Utah.

Visit our website www.moraneyecenter.org

John a.Moran eye center

65 Mario capecchi drive

Salt lake city, ut 84132

801.581.2352