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our FOCUS finding a cure. 2016 ANNUAL REPORT “If you’ve got glaucoma, GRF is the best community out there— they’re looking forward for the cure.” – Catherine Wilmoth and her son, Christopher who was diagnosed with glaucoma when he was 7 months old.

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Page 1: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

“No one should have to fear blindness from glaucoma.”

– Thomas M. Brunner, President and CEO

“We accelerate new and safe solutions for glaucoma patients.”

– Andrew G. Iwach, MD, Chair, Board of Directors

251 Post Street, Suite 600, San Francisco, CA 94108 – (415) 968-3162 – www.glaucoma.org

GRF CouncilA national leadership council of physicians working with GRF to improve access to informative and unbiased educational materials for all glaucoma patients.

Chair, GRF CouncilCarl Migliazzo, MD

(Central Regional Councilor)

GRF Councilors Stuart F. Ball, MDRobert J. Barnes, MDMichael S. Berlin, MDKathryn Bollinger, MDSteven V.L. Brown, MD, FACSDean Carlson, MD John S. Cohen, MD

(Midwest Regional Councilor)Randy Craven, MDRobert J. Derick, MDMonte Dirks, MDAmish Doshi, MDDoreen Fazio, MDRobert Feldman, MD

(Southwest Regional Councilor)Gloria P. Fleming, MDDavid Gilbert, MDLinda Greff, MDAgnes Huang, MDDan Jewelewicz, MDMartin B. Kaback, MDL. Jay Katz, MD

(Northeast Regional Councilor)Anup Khatana, MDDouglas Kohl, MDMichael S. Korey, MDRohit Krishna, MDRishi Kumar, MD

Linda Lawrence, MDRichard Lehrer, MDSteve Litinsky, MD

(Southeast Regional Councilor)Charles McMahon, MD

(Mountain Regional Councilor)Anne Miller, MDKevin Miller, MDJohann Ohly, MDDavid J. Palmer, MDCindy Penzler, MDJames Plotnik, MD, FACSAndrew Prince, MDAndrew Rabinowitz, MDGeorge Reiss, MDMichael Sakamoto, MD

(Western Regional Councilor)Keith Sanford, MDSonja W. Schluter, MD, MPHBradley Schuster, MD

(Mountain Regional Councilor)Arthur L. Schwartz, MDDonald Schwartz, MDGail F. Schwartz, MDMy Le Shaw, MDRajesh Shetty, MDCharles Eric Shrader, MDOluwatosin Smith, MD

(Southwest Regional Councilor)Michael Stiles, MDShigemi Sugiki, MDThomas Tayeri, MDSteven Vold, MD

(Southern Regional Councilor)Brian Welcome, MDMark Werner, MDRuth D. Williams, MD

(Midwest Regional Councilor)Jeffrey Zink, MD

VISIONfor life.

Dear Friends,

At Glaucoma Research Foundation, our bold vision is a future without glaucoma. With generous support from you and others dedicated to our mission we can make Vision for Life a reality for all those at risk and suffering from glaucoma. We are a catalyst for game-changing diagnostics, for innovative treatment options, and ultimately for a cure. This bold vision requires

intense focus, careful planning, thoughtful and creative research funding, and meaningful education and outreach. Thank you for your ongoing partnership. Together, we are closer than ever to achieving Vision for Life for all who have glaucoma and are at risk of glaucoma.

Andrew G. Iwach, MDChair, Board of Directors

Thomas M. BrunnerPresident and CEO

our FOCUSfinding a cure.

2016 ANNUAL REPORT

“If you’ve got glaucoma, GRF is the best community out there— they’re looking forward for the cure.”

– Catherine Wilmoth and her son, Christopher who was diagnosed with glaucoma

when he was 7 months old.

Page 2: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

“No one should have to fear blindness from glaucoma.”

– Thomas M. Brunner, President and CEO

“We accelerate new and safe solutions for glaucoma patients.”

– Andrew G. Iwach, MD, Chair, Board of Directors

251 Post Street, Suite 600, San Francisco, CA 94108 – (415) 968-3162 – www.glaucoma.org

GRF CouncilA national leadership council of physicians working with GRF to improve access to informative and unbiased educational materials for all glaucoma patients.

Chair, GRF CouncilCarl Migliazzo, MD

(Central Regional Councilor)

GRF Councilors Stuart F. Ball, MDRobert J. Barnes, MDMichael S. Berlin, MDKathryn Bollinger, MDSteven V.L. Brown, MD, FACSDean Carlson, MD John S. Cohen, MD

(Midwest Regional Councilor)Randy Craven, MDRobert J. Derick, MDMonte Dirks, MDAmish Doshi, MDDoreen Fazio, MDRobert Feldman, MD

(Southwest Regional Councilor)Gloria P. Fleming, MDDavid Gilbert, MDLinda Greff, MDAgnes Huang, MDDan Jewelewicz, MDMartin B. Kaback, MDL. Jay Katz, MD

(Northeast Regional Councilor)Anup Khatana, MDDouglas Kohl, MDMichael S. Korey, MDRohit Krishna, MDRishi Kumar, MD

Linda Lawrence, MDRichard Lehrer, MDSteve Litinsky, MD

(Southeast Regional Councilor)Charles McMahon, MD

(Mountain Regional Councilor)Anne Miller, MDKevin Miller, MDJohann Ohly, MDDavid J. Palmer, MDCindy Penzler, MDJames Plotnik, MD, FACSAndrew Prince, MDAndrew Rabinowitz, MDGeorge Reiss, MDMichael Sakamoto, MD

(Western Regional Councilor)Keith Sanford, MDSonja W. Schluter, MD, MPHBradley Schuster, MD

(Mountain Regional Councilor)Arthur L. Schwartz, MDDonald Schwartz, MDGail F. Schwartz, MDMy Le Shaw, MDRajesh Shetty, MDCharles Eric Shrader, MDOluwatosin Smith, MD

(Southwest Regional Councilor)Michael Stiles, MDShigemi Sugiki, MDThomas Tayeri, MDSteven Vold, MD

(Southern Regional Councilor)Brian Welcome, MDMark Werner, MDRuth D. Williams, MD

(Midwest Regional Councilor)Jeffrey Zink, MD

VISIONfor life.

Dear Friends,

At Glaucoma Research Foundation, our bold vision is a future without glaucoma. With generous support from you and others dedicated to our mission we can make Vision for Life a reality for all those at risk and suffering from glaucoma. We are a catalyst for game-changing diagnostics, for innovative treatment options, and ultimately for a cure. This bold vision requires

intense focus, careful planning, thoughtful and creative research funding, and meaningful education and outreach. Thank you for your ongoing partnership. Together, we are closer than ever to achieving Vision for Life for all who have glaucoma and are at risk of glaucoma.

Andrew G. Iwach, MDChair, Board of Directors

Thomas M. BrunnerPresident and CEO

our FOCUSfinding a cure.

2016 ANNUAL REPORT

“If you’ve got glaucoma, GRF is the best community out there— they’re looking forward for the cure.”

– Catherine Wilmoth and her son, Christopher who was diagnosed with glaucoma

when he was 7 months old.

Page 3: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

“Our proposed experiments can potentially develop treatments that target early pathological events.”

Richard T. Libby, PhDAssociate Professor, Department of Ophthalmology,

University of Rochester Medical School, Flaum Eye Institute, Rochester, New York

4 13

vision for LIFEtogether we can stop blindness from glaucoma.

Board of Directors

Board ChairAndrew G. Iwach, MDGlaucoma Center of San FranciscoSan Francisco, CA

President and CEO Thomas M. BrunnerGlaucoma Research FoundationSan Francisco, CA

Vice ChairRobert L. Stamper, MDUniversity of CaliforniaSan Francisco, CA

SecretaryRick Halprin, CPADirector, Professional Affairs (retired)Forth Worth, TX

TreasurerCharles R. Wilmoth Wells Fargo Advisors, LLC San Francisco, CA

DirectorsFrederick H. BrinkmannDirector, Information Technology (Retired)Santa Rosa, CA

Timothy J. DwyerPrivate InvestorWoodside, CA

Adrienne L. Graves, PhDIndependent DirectorSan Francisco, CA

Yehia Hashad, MD Allergan, Inc.Irvine, CA

Linda C. LinckDelta Gamma FoundationLafayette, CA

Dennis E. SingletonSpieker PartnersMenlo Park, CA

Monica L. Vetter, PhDUniversity of UtahSalt Lake City, UT

Martin B. Wax, MDPanOptica, Inc.Bernardsville, NJ

Ruth D. Williams, MDWheaton Eye ClinicWheaton, IL

Mona ZanderThe Mona and Ed Zander Family FoundationCarmel, CA

Founders John Hetherington, Jr., MDUniversity of CaliforniaSan Francisco, CA

H. Dunbar Hoskins, Jr., MDAmerican Academy of Ophthalmology (Retired)San Francisco, CA

Robert N. Shaffer, MD(1912–2007)

Honorary Advisory BoardF.T. BarrAfex International, Inc.Houston, TX

June Behrendt OttoThe Edward J. Daly FoundationSan Francisco, CA

Sarah BrownSan Francisco, CA

Steven KirschSan Jose, CA

Roger McGuinnWindemere, FL

Robert C. NevinsLafayette, CA

David E.I. Pyott Former Chairman and CEO of Allergan, Inc. Irvine, CA

Cary R. Rayment Alcon, Inc. (Retired) Cle Elum, WA

Professional StaffThomas M. BrunnerPresident and CEO

Nancy GraydonExecutive Director of Development

Andrew L. JacksonDirector of Communications

Catalina San AgustinDirector of Operations

Aileen TrieuAssociate Director of Development

Christie D’AngeloAssistant Director, Events and Volunteer Management

Michelle DavidsonEvent Program Manager

Briana FosterDevelopment Assistant

research VISION

Some of the most important discoveries in scientific research come from an investigator with a new, untested idea who needs funding to explore a creative project.

“The Shaffer program is perfect for young researchers with exciting ideas but little funding.”

Tonia Rex, PhDVanderbilt Eye Institute Director of Resident Research

and Co-Director of the Gene and Protein Analysis Module in the Vanderbilt Vision Research CenterVisit glaucoma.org/grants to learn more about our 2016 research grants..

We know that research is the answer—research built on the knowledge and discoveries of many scientists and laboratories. The 2016 research grants were made possible through leadership gifts from The Frank Stein and Paul S. May Grants for Innovative Glaucoma Research,

The Alcon Foundation, The Melza M. and Frank Theodore Barr Foundation, Inc., the Dr. Henry A. Sutro Family Grant for Research, and Dr. James and Elizabeth Wise. These one-year research grants were funded at $40,000 each to explore promising new ideas.

2016 RESEARCH GRANTSresearch holds the answers…and the cure.

3

Evan B. Stubbs, Jr., PhD Edward Hines, Jr.

VA Hospital, Hines, Illinois

Frank Talke, PhDUniversity of California, San Diego, California

David T. Stark, MD, PhDStein Eye Institute,

David Geffen School of Medicine at UCLA,

Los Angeles, California

Ian Pitha, MD, PhDJohns Hopkins University,

Wilmer Eye Institute, Baltimore, Maryland

Carla J. Siegfried, MDWashington University

School of Medicine, St. Louis, Missouri

W. Daniel Stamer, PhDDuke University Eye Center

Durham, North Carolina

Kevin Park, PhDUniversity of Miami Miller

School of Medicine, Miami, Florida

Louis R. Pasquale, MDCo-investigator

Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School,

Boston, Massachusetts

David A. Sullivan, MS, PhD, FARVO

“Support from GRF allowed me to use creative and alternative approaches to my research.”

Sayoko E. Moroi, MD, PhDProfessor, Ophthalmology and Visual Sciences,

Kellogg Eye Center, University of Michigan

“The grant from GRF was critically important for our new research strategy.”

Thomas A. Reh, PhDProfessor, Department of Biological Structure, University of Washington School of Medicine,

Seattle, Washington

Page 4: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

“Our proposed experiments can potentially develop treatments that target early pathological events.”

Richard T. Libby, PhDAssociate Professor, Department of Ophthalmology,

University of Rochester Medical School, Flaum Eye Institute, Rochester, New York

4 13

vision for LIFEtogether we can stop blindness from glaucoma.

Board of Directors

Board ChairAndrew G. Iwach, MDGlaucoma Center of San FranciscoSan Francisco, CA

President and CEO Thomas M. BrunnerGlaucoma Research FoundationSan Francisco, CA

Vice ChairRobert L. Stamper, MDUniversity of CaliforniaSan Francisco, CA

SecretaryRick Halprin, CPADirector, Professional Affairs (retired)Forth Worth, TX

TreasurerCharles R. Wilmoth Wells Fargo Advisors, LLC San Francisco, CA

DirectorsFrederick H. BrinkmannDirector, Information Technology (Retired)Santa Rosa, CA

Timothy J. DwyerPrivate InvestorWoodside, CA

Adrienne L. Graves, PhDIndependent DirectorSan Francisco, CA

Yehia Hashad, MD Allergan, Inc.Irvine, CA

Linda C. LinckDelta Gamma FoundationLafayette, CA

Dennis E. SingletonSpieker PartnersMenlo Park, CA

Monica L. Vetter, PhDUniversity of UtahSalt Lake City, UT

Martin B. Wax, MDPanOptica, Inc.Bernardsville, NJ

Ruth D. Williams, MDWheaton Eye ClinicWheaton, IL

Mona ZanderThe Mona and Ed Zander Family FoundationCarmel, CA

Founders John Hetherington, Jr., MDUniversity of CaliforniaSan Francisco, CA

H. Dunbar Hoskins, Jr., MDAmerican Academy of Ophthalmology (Retired)San Francisco, CA

Robert N. Shaffer, MD(1912–2007)

Honorary Advisory BoardF.T. BarrAfex International, Inc.Houston, TX

June Behrendt OttoThe Edward J. Daly FoundationSan Francisco, CA

Sarah BrownSan Francisco, CA

Steven KirschSan Jose, CA

Roger McGuinnWindemere, FL

Robert C. NevinsLafayette, CA

David E.I. Pyott Former Chairman and CEO of Allergan, Inc. Irvine, CA

Cary R. Rayment Alcon, Inc. (Retired) Cle Elum, WA

Professional StaffThomas M. BrunnerPresident and CEO

Nancy GraydonExecutive Director of Development

Andrew L. JacksonDirector of Communications

Catalina San AgustinDirector of Operations

Aileen TrieuAssociate Director of Development

Christie D’AngeloAssistant Director, Events and Volunteer Management

Michelle DavidsonEvent Program Manager

Briana FosterDevelopment Assistant

research VISION

Some of the most important discoveries in scientific research come from an investigator with a new, untested idea who needs funding to explore a creative project.

“The Shaffer program is perfect for young researchers with exciting ideas but little funding.”

Tonia Rex, PhDVanderbilt Eye Institute Director of Resident Research

and Co-Director of the Gene and Protein Analysis Module in the Vanderbilt Vision Research CenterVisit glaucoma.org/grants to learn more about our 2016 research grants..

We know that research is the answer—research built on the knowledge and discoveries of many scientists and laboratories. The 2016 research grants were made possible through leadership gifts from The Frank Stein and Paul S. May Grants for Innovative Glaucoma Research,

The Alcon Foundation, The Melza M. and Frank Theodore Barr Foundation, Inc., the Dr. Henry A. Sutro Family Grant for Research, and Dr. James and Elizabeth Wise. These one-year research grants were funded at $40,000 each to explore promising new ideas.

2016 RESEARCH GRANTSresearch holds the answers…and the cure.

3

Evan B. Stubbs, Jr., PhD Edward Hines, Jr.

VA Hospital, Hines, Illinois

Frank Talke, PhDUniversity of California, San Diego, California

David T. Stark, MD, PhDStein Eye Institute,

David Geffen School of Medicine at UCLA,

Los Angeles, California

Ian Pitha, MD, PhDJohns Hopkins University,

Wilmer Eye Institute, Baltimore, Maryland

Carla J. Siegfried, MDWashington University

School of Medicine, St. Louis, Missouri

W. Daniel Stamer, PhDDuke University Eye Center

Durham, North Carolina

Kevin Park, PhDUniversity of Miami Miller

School of Medicine, Miami, Florida

Louis R. Pasquale, MDCo-investigator

Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School,

Boston, Massachusetts

David A. Sullivan, MS, PhD, FARVO

“Support from GRF allowed me to use creative and alternative approaches to my research.”

Sayoko E. Moroi, MD, PhDProfessor, Ophthalmology and Visual Sciences,

Kellogg Eye Center, University of Michigan

“The grant from GRF was critically important for our new research strategy.”

Thomas A. Reh, PhDProfessor, Department of Biological Structure, University of Washington School of Medicine,

Seattle, Washington

Page 5: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

SCIENTIFIC ADVISORSBalwantray Chauhan, PhDDalhousie University, Nova Scotia

George A. Cioffi , MDColumbia University College of Physicians and Surgeons

Anne L. Coleman, MD, PhDStein Eye Institute, UCLA

Scott Fraser, PhDUniversity of Southern California

Christopher A. Girkin, MDUniversity of Alabama at Birmingham

David S. Greenfi eld, MDUniversity of Miami

Steven L. Mansberger, MD, MPHDevers Eye Institute/Legacy Health

Martin Raff , MDUniversity College, London

Douglas Rhee, MD Case Western Reserve University School of Medicine

Joel S. Schuman, MDNew York University School of Medicine

Ernst R. Tamm, MDUniversity of Regensburg, Germany

Monica Vetter, PhDUniversity of Utah

Martin B. Wax, MDPanOptica, Inc.

Arthur J. Weber, PhDMichigan State University

Janey L. Wiggs, MD, PhDMassachusetts Eye & Ear Infi rmary

5

• Founded 1978 in San Francisco

• Speeding the cure through research collaboration

• Raising awareness and educating the public

• Leading the way in glaucoma research until a cure is found

Prevent vision loss from glaucoma by investing in innovative research, education, and support with

the ultimate goal of fi nding a cure.

Glaucoma Research Foundation

MISSION.

2016_GRF_AnnualReport_body_v12_FinalMechanical.indd 1 10/31/16 11:30 AM

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6

the CATALYST FOR A CURE keeping the cure in sight.

The Catalyst for a Cure research team brings together four laboratories, each with a specific skill, to work together to discover new biomarkers. Sensitive biomarkers will help doctors diagnose glaucoma earlier and treat it more effectively. In 2016 the team has made significant progress toward biomarker validation for clinical use.

Alfredo Dubra, PhDAssociate Professor of Ophthalmology and Biophysics

Department of Ophthalmology, The Eye InstituteMedical College of Wisconsin

“We borrow ideas from astronomy, microscopy, mathematics, even chemistry and apply them to the

study of glaucoma.”

Jeffrey L. Goldberg, MD, PhDProfessor and Chair of Ophthalmology

The Byers Eye Institute at Stanford

“The Biomarker Initiative catalyzes our ability to move candidate therapies from the laboratory to the clinic.”

Andrew Huberman, PhDAssociate Professor, Departments of Neurobiology

and Ophthalmology Stanford University School of Medicine

“We are deeply committed to making a difference in the lives of glaucoma patients.”

“Biomarkers can detect the progression of glaucoma at a stage where it can be prevented.”

Vivek Srinivasan, PhDAssistant Professor of Biomedical Engineering

University of California, Davis Department of Biomedical Engineering

Page 7: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

7

CATALYST FOR A CUREbiomarker initiative.

Learn more at glaucoma.org/catalyst

What are Biomarkers? And Why are they So Important?

Early detection. Early diagnosis is the key to preventing vision loss. Sensitive biomarkers hold the potential to let doctors detect the disease early, before sight is permanently lost.

More effective treatment. Biomarkers could help doctors learn sooner if a treatment is working or not, helping them to treat glaucoma patients more effectively.

Faster drug discovery. Glaucoma progresses slowly. An effective biomarker could demonstrate the efficacy of a drug more quickly and accelerate federal approval for new treatments.

Closer to a cure. The more we understand about biomarkers the closer we are to discovering the root causes of the disease—and the cure.

Page 8: FOCUS - Glaucoma Research Foundation · Robert Feldman, MD ... Donald Schwartz, MD. Gail F. Schwartz, MD My Le Shaw, MD. Rajesh Shetty, MD ... intense focus, careful planning, thoughtful

8

2016 FINANCIAL REPORT investing your donations wisely and responsibly.

Total revenue for the fiscal year ended June 30, 2016 was $3.8 million. Through generous support from our donors, $3.5 million was committed to essential glaucoma research and education programs. Glaucoma Research Foundation continues to have a strong balance sheet, finishing the year with total assets of $9.7 million.

Independent nonprofit evaluators Charity Navigator and GuideStar give us high ratings for transparency and accountability. Our audited financial reports are available on our website and we meet all 20 of the Better Business Bureau’s Standards for Charity Accountability. Careful stewardship ensures that 86 cents of every dollar donated goes directly to research and education programs.

This year we have committed one million dollars to the collaborative Catalyst for a Cure Biomarker Initiative. This type of major commitment requires steadfast support. We need your help to close a funding gap and meet our ambitious goals in the coming fiscal year.

Thank you for your personally significant contributions and your ongoing advocacy to help speed the cure.

Charles WilmothTreasurer

4%Foundations

9%Conferences

1%Corporations

86%Individuals

Revenue

63%Research

Expenses

23%Education

11%Development

3% Administration

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9

Glaucoma Research Foundation

Statement of Financial Position as of June 30, 2016*

Statement of Activities for the Year Ended June 30, 2016*2016 2015

UnrestrictedTemporarily

RestrictedPermanently

Restricted Total TotalSUPPORT AND REVENUE Donations and bequests $2,166,042 $955,297 – $3,121,339 $2,912,057 Special Events, net of expenses 418,260 – – 418,260 502,199 Other Income/Reductions 3,861 – – 3,861 15,358 Investment Income (10,438) (69,599) – (80,037) 291,670 Change in value of charitable trusts (3,162) – – (3,162) 8,591 Conference/Forum income 363,400 – – 363,400 252,857 Assets released from restrictions 430,269 (430,269) – - – Total Revenue, gains, & support 3,368,232 455,429 – 3,823,661 3,982,732 EXPENSES Research Programs 2,544,735 - - 2,544,735 2,347,906  Education Programs 919,803 - - 919,803 917,912  Administration 129,534 - - 129,534 114,367  Fundraising 426,857 - - 426,857 446,257 Total Expenses 4,020,929 4,020,929 3,826,442

Change in Net Assets (652,697) 455,429 (197,268) 156,290  Net Assets, beginning of year 3,235,752 1,850,108 3,342,500 8,428,360 8,272,100 Net Assets, end of year $2,583,055 $2,305,537 $3,342,500 $8,231,092 $8,428,390

ASSETS 2016 2015CURRENT ASSETS

Cash $1,249,612 $666,585 Pledges and bequests receivable 390,278 186,610 Prepaid expenses 111,952 118,567 Booklet inventory 35,330 31,822 TOTAL CURRENT ASSETS 1,787,172 1,003,584

NON-CURRENT ASSETSPledges and bequests receivable (net of present value discount and current portion)

592,523 108,000

Assets held in trust (at market value) 188,742 191,947 Investments (at market value) 3,743,727 4,959,650 Furniture and equipment (net of depreciation) 28,476 33,096 Permanently restricted cash 3,342,500 3,342,500 TOTAL NON-CURRENT ASSETS 7,895,968 8,635,193 TOTAL ASSETS $9,683,140 $9,638,777

LIABILITIES AND NET ASSETSCURRENT LIABILITIES

Accounts payable and accrued expenses 134,434 50,261 Trusts, distributions payable, current portion 22,131 25,907 Grants payable 1,192,500 1,035,000 TOTAL CURRENT LIABILITIES 1,349,065 1,111,168

NON-CURRENT LIABILITIESLiabilities to trust beneficiaries (at present value) 102,953 99,219 TOTAL LIABILITIES 1,452,018 1,210,387

NET ASSETSUnrestricted 2,583,085 3,235,782 Temporarily restricted 2,305,537 1,850,108 Permanently restricted net assets 3,342,500 3,342,500 TOTAL NET ASSETS 8,231,122 8,428,390 TOTAL LIABILITIES AND NET ASSETS $9,683,140 $9,638,777

*Audited Financial Report

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10

In AppreciationWe express our deepest appreciation to all of our donors. Each and every gift is essential and assists us with forwarding our important mission.

The following is a listing of contributors of $500 or more from July 1, 2015 to June 30, 2016.

CORPORATIONS AND FOUNDATIONSBenefactors($100,000 to $199,999)The Alcon Foundation, Inc.

Pacesetters($25,000 to $49,999)Alcon Laboratories, Inc.The Allergan FoundationAllergan, Inc.Bausch + LombEdward Joseph Daly

FoundationMedical Research CharitiesMUFG Union Bank N.A. Ora, Inc.

Patrons($10,000 to $24,999)Aerie Pharmaceuticals, Inc.Akorn, Inc.Canon USA, Inc.Carl Zeiss Meditec, Inc.Carol Young Brooke

FoundationDodge & CoxElite Island ResortsGenentech, Inc.Glaukos CorporationMellam Family FoundationNew World Medical, Inc.Santen, Inc.ShireSun Pharmaceutical

Industries, Inc.

Sponsors($5,000 to $9,999)Allstate Life Insurance

CompanyDelta Gamma FoundationDiopsys, Inc.

Ellex, Inc.Heidelberg Engineering,

Inc.Icare USAInotek Pharmaceuticals

CorporationIridex CorporationLumenis, Inc.Neighbor To NationNidek, IncOcular Therapeutix, Inc.Optovue, Inc.Pfund Family FoundationRobert John Russo GalleryTranscend Medical, Inc.Voxeleron LLC

President’s Club($1,000 to $4,999)Atherton Plastic SurgeryAvellino LabsBeaver-Visitec

International, Inc.Elsewhere Advertising &

CommunicationsHotel del CoronadoImperial Hotel, TokyoIronman Foundation, Inc.Johnson & Johnson Family

of CompaniesKatenaMacy’s FoundationMai Land CorporationMarket Scope, LLCMaryland Charity

CampaignMega HertzNeoMedix CorporationNovaBay Pharmaceuticals,

Inc.Ophthalmic Mutual

Insurance CompanyThe Palace HotelSaks Fifth Avenue, Union

SquareSanDisk Corporation

Matching Gift ProgramShaler Area High SchoolSpirit Airlines

Contributors($500 to $999)Chevron Humankind

Employee Funds

Concrete Technology Corporation

Disneyland ResortGE FoundationHaag-Streit USA, Inc.Hinomaru Limousine Co.,

Ltd.Hyatt Lodge at McDonald’s

CampusKaur PhotographyLarabarLynnwood Retired Eagles

Activity ClubMarines’ Memorial

AssociationMichael Merrill Design

CenterMicrosoft Matching Gifts

ProgramOakley, Inc.Presidio Golf ClubPRP Wine InternationalShopifyThe Boeing Company Gift

Matching Programthrive SF FitnessWines for Humanity

INDIVIDUALSVisionaries($200,000+)Rubin - Obstgarten - Cohn

FamilyMona and Edward Zander

Benefactors($100,000 to $199,999)Charlot and Dennis E.

SingletonLiz Stratton

Founders ($50,000 to $99,999)Mr. and Mrs. F.T. BarrOlcott Family Foundation

Pacesetters($25,000 to $49,999)Wallace and Thomas M.

BrunnerMargaret and Russell

GarvinCarie and Larry HaimovitchSteven and Michele Kirsch

Rose J. LemIris and Lawrence LernerMary E. PittmanSchacknow Family

Foundation, Inc.Dr. James and Elizabeth

Wise

Patrons($10,000 to $24,999)Michael and Darlene

ArnoldSarah and Bill BrownJill and Michael ChmuraGermaine and Timothy

Dwyer, Wendy Dwyer Memorial

Mrs. Frances Vaughan Hunt

Andrew G. Iwach, MDRoberta R.W. KamedaThe Link FamilyJames and Rebecca

MorganJanet and Cary RaymentMargaret ReynoldsRobert H. and Terri L. Cohn

Family FoundationVirginia M. ShafferEmmett Skinner, Jr.Frank SteinAnupama and Matthew

TateCatherine and Charles

Wilmoth

Sponsors($5,000 to $9,999)Chris W. Allen, DVMArlene Anthony and

Thomas BradshawFrederick H. and Cynthia L.

BrinkmannPaul and Paula ChaneyBarry FriedbergFrank and Joseph Gila

FundAdrienne L. Graves, PhDDavid S. KlineCharles and Jane KusekPatricia LeeLawrence S. Lipkind, DDSKathryn MayerDhun Mehta

our BOLD VISION the cure is in sight.

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11

Judith and Charles Munnerlyn, PhD

Angela Nomellini and Kenneth E. Olivier

David T. Richardson, West Charitable Trust

Stephanie Twomey Roche and N. D’Arcy Roche

Randolph C. RoederJohn RussellNaomi and Robert

Stamper, MDLisa and Martin B. Wax, MDTodd ZanderThelma H. Zeller

Catalyst Circle($1,000 to $4,999)Allen S. Taylor FoundationThea AmbergFred AmorosoMr. Roger AndersonWeston and Jeannette

AndersonBetty J. AnnisAnonymousK. Arakelian FoundationThomas BakerMichael S. BarishDaniel BarryLezlie BeamHugh Beckman, MDTatyana BeldockArleen and Robert BelyeaSusan BentonMichael Bergamini, PhDRobert F. Blitzer and XenryRichard BondurantLori and Allen BouchChris BrasfieldGermaine BrennanGreta and Tom BriodyJ.A. BrownReay Brown, MDJames and Linda CafritzThe Charles Henry Smith

Sr. FoundationNobuko Saito Cleary and

Gary Cleary, PharmD, PhDKathy and Jeff CongdonAlan S. Crandall, MDC. Seth CunninghamSis and Bert DamnerMichael DarlingPhuong Mai DauMarc de AngelisNathaniel De RothschildSeth DeAvilaThe Bodri Foundation of

the Jewish Community Endowment

Victoria and Donald F. DeMuth

Molly and Brett DickKimberly Eckstein

Amanda EddyWilliam EdlundCarolyn B. EdwardMichael and Tracey

ElfstromEmily FarinaRobert D. Fechtner, MDMarilyn A. Fenneman and

Alex ForresterDonald FishbeinAnthony R. Fisher, PhDScott J. Fudemberg, MDMartin and Gwen GansGilbert H. GatesMarlene GerbsmanLaRue R. Gibson, Jr.Judy F. Gordon, DVMNancy M. GraydonGary GreenbergRichard C. GreenwaldCathy and Rod GremaudSharlene and Alfred Hall,

PharmDCarol M. HallLouise and Rick Halprin,

CPATracy HammondMarjorie D. HartYehia Hashad, MDPaul HeimanJohn Hetherington, Jr., MDAnn and H. Dunbar

Hoskins, Jr., MDTakashi IizukaManraj JohlThe Kahn FoundationRobert KarpJerrold KeilsonJean D. KliewerMartin KnightBradey KroneAndrew J. KujawaMark R. and Rae N.

LemberskyNorma S. LenhertAlvin and Rosanne LevittRichard A. Lewis, MDGrace LinLinda and Donald Linck,

DDSMargaret LondonJane R. LurieMrs. Donna F. MahinGrace and George R.

Marcellino, PhDIsao S. MatsuuraLiam MayclemJulia J. McMahonAndrew C. Meyer, Jr.Michael and Ina Korek

Foundation TrustElizabeth B. and Carl V.

Migliazzo, MDChris and Anny Monteilh

James R. Morano, PhDRobert and Maura MoreyChristopher M. MorganLawrence and Liz MorrisSeymour and Pearl

MoskowitzGeeta Narendra AhyaCarolyn M. NeerhofDebbie and Robert C.

NevinsMarjorie A. NevittHoward NodellVincent E. O’BrienMasashi OkaJudy F. OliphantCharlotte L. PettyDenise and Sam PolakoffRobert L. PondelicekDeirdre Porter and

Bradford HallHardy and Ellie PrenticeDavid E. I. PyottP. Anthony RidderCarol and George RogersPatricia A. RospendaDonald Schwartz, MDKaren Schwartz and Sam

ShelanskiAlan and Ellyn

SeelenfreundPatrick J. ShulerSaul SiemaskaMary R. SkuceTerry and Peggy SlatteryLaine and Carl SmithStephen E. SmithJeffrey and Nancy SoluriMichael SpeyerRichard SteegstraTania W. StepanianBill and Jane StocklinLynn StreimJoyce SuchslandShigemi Sugiki, MD, FACSArthur S. TakaharaCatherine and Richard TateHarry T. Tate, MDMarian and Julius Tills

Endowment Fund of the Dallas Jewish Community Foundation

Dr. and Mrs. Thomas G. Todaro

Carolyn and Matthew Vanderberg

Monica Vetter, PhDRebecca and Steven

VilendrerBarbara and Robert VossVincent A. WallaceAngela Webb, Moon

JoggersWendy Weisler

Dr. and Mrs. George M. Weston, In Loving Memory of Daniel S. Weston

Sally O. WhiteJohn and Cynthia WiedCandace WilliamsRuth D. Williams, MD and

Stephen C. Gieser, MD, MPH

Leslie and Mike WinnHarvey and Susan

WittenbergKatherine A. WoodBruce and Katrina

WoodskeRatna K. Yadla, MDCheryl and Thomas YoungJackie and Phillip Young

Contributors($500 to $999)Robert AdamsRory AndersonStephen AndolinaPaul Ashton, PhDJack and Carol AtenArthur BackMurat BadayDavid BaileyMary and Timothy BarnesJ. Bronwyn Bateman, MD

and Douglas Hershey, MDMicah BatesNancy and Joseph BlumJeffrey BoyumBreitman Family

Foundation, Inc.Chris BrownWilliam F. CaelJoan CarrollJermaine ChristieWilliam and Michele

CiganekJeff ClelandRob CookCraig Corbitt and Nancy

StoltzThomas CordaroEmmett Cunningham, Jr.,

MD, PhD, MPHKen J. DamozonioEdward DanseDick DavisMaryam Mehri DehnaviDiana Leis DelkerVenkat and Prema

DevarajanJeffrey J. DrzazgowskiKim EnnisSharon FarahaniSina FatehSteven and Debra FendrichJeff Finer, MDDan Finkle

Continued from page 10.

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Douglas C. Fisher, MDElizabeth FlaggCynthia FosterDoug FosterDr. Larry FreemanBradley FundingslandKen GaltMike GaranziniZoya GargiuloCraig GermanAvanti GhanekarSusan Glikbarg HansonPhillip GoodingMargaret and Joseph F.

GovednikLisa GrilloneMr. and Mrs. Harold E.

GuentherKinta HallerMartha HamiltonRobert T. HarkerKaren HarrisPaul Harvey, Jr.Peggy HawkinsTheresa HeahPatrick Healy, MPHHarold U. HernandezLilo HoffmanLes and Eleanore HolveLori and Mark HorneKamran HosseiniVera HsuDr. Charles A.C. JohnsonDan Joraanstad and

Bob HermannJim KasicTooran KhayambashiHugh KirkpatrickDaniel KohaneBill and Carolyn KolzowSusan KramerDr. Jens KratholmAchim H. KraussGrace David LandDiane LeeElizabeth A. Lee and

Marty OsterKen LeongRobert Levine, MDHoward and Susan LichtRandy LindholmLaura and Steven M.

Litinsky, MDDr. Fenghe LuAndrew LukRobert and Delores LyonsKelley MacDonald and R.

Thomas Martell, Jr.Leah MakleyLinda MarcinekMorten MarottRev. and Mrs. Alexander

McLachlanStanley Michael

Dorothy M. MilesJoan and Wayne MillerSandra MossDavid and Jane NewsomWeston NicholsThomas J. NicoGeorge N. NikopoulosAnthony and Linda NolanT. Michael Nork, MDDona and Gary D. Novack,

PhDVandy O’ReillyJohn and Alice OstermanAnton PetrovNancy and Charles PhilippChristine PhippsStephanie PilgrimMichael PiserAlan and Carol PomerantzGene M. PranzoRory PridayMary Jane Rafii, MBA, PhDFederico RampiniGale RichardsMichael Robinson, MDAndrew RockefellerMichael RoweCheryl Rowe-Rendleman,

PhDAnne L. Brody RubinRoman Rubio, MDSusan Ryu, MD and

Michael Gaynon, MDMisako M. SackRonald SandersRobert and Rosemary

SchafferSheila SchleeCharles L. SchmidtSusan SchneiderTodd ScottErik ScramagliaAndrew SedgwickCharles Semba, MDTimothy SenoGrace SetoNaj Sharif, PhDKen ShimokawaEdwin Shonfeld, MDErwin Si, PhDNicholas SiemaskaNelson SingletonRobert SpratlinVivek Srinivasan, PhDDouglas StewardMartha C. StisserErich StraussCraig SundstromEmiko SungWilliam SwartJohn D. SwayzeJames Tan, MD, PhDSarah TaoKevin Tausend

Kathy M. ThomasVincent TuccilloTracy Valorie, BS, MBADavid Van MeterMargrit VanderrynHazel H. WadaGary Walker, PhDMargo WalkerBrian A. Welcome, MDJane Weston, MD and Jan

Horn, MDBarbara Wirostko, MDSue and Richard WollackPeter WooYi YinM.P. and B. J. Zimprich

ADDITIONAL CONTRIBUTORSWe are grateful to the more than 3,200 donors who have contributed in fiscal year 2016 to forward our mission. Thank you for your steadfast support.

THE BLANCHE MATTHIAS SOCIETY

The Blanche Matthias Society recognizes those individuals who have included Glaucoma Research Foundation in their estate plans. We are grateful to the following individuals who have notified us of their intent to include us as a beneficiary in their wills, trusts, or other investment vehicles. Steven AberblattMariLynn BagienskiSchuyler and Susie BaileyAndrew BalabanDiana BelliveauGerald BeresniewiczBarbara J. BethuneFrances O. BlairWallace and Thomas M.

BrunnerBarbara R. ConwayDonald J. Digby, MD, FACS,

FAAORobert J. DrabkinSharon EntwistleArla EscontriasCharleen Evans-Thomas,

EdDJohn FilozofMarina L. Flores

Carol GasiorekE. Y. and William O. GeisertGloria GreenleeLarry HaimovitchRon Strickland and

Christine HartmannRuth M. HenningAndrew G. Iwach, MDVirginia Johansen-HudnallEsther JonesShirley KalgaardArlyne KrumNancy LamLaurence LandeSharon LeahyDonald LoeschCharles K. LongJane R. LurieRichard MalmDolores NievesNunes Living TrustMarnay O’NealCharlotte L. PettyPatricia A. PomerleauBetty RiessBarbara J. RitzenthalerCheryle RostMary J. SchaafJudith SchnorfMarianne SeidenbergerEmmett Skinner, Jr.Sara Marie SmithMary Ann SpicerBurton SpillerWilliam SteckowichFrank SteinBrian P. VaughanCarol E. VistnesMichael T. WalczykMel WalkerCraig T. WoodburyAnd three anonymous

members

For more information on the Blanche Matthias Society, visit our website at glaucoma.org/involved or contact us at 415-986-3162.This honor roll is composed of major donors who supported Glaucoma Research Foundation from July 1, 2015 to June 30, 2016. If your name has been omitted or there is an error in the listing, we ask that you notify us at 251 Post Street, Suite 600, San Francisco, CA 94108 or call 415-986-3162.

Continued from page 11.

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“Our proposed experiments can potentially develop treatments that target early pathological events.”

Richard T. Libby, PhDAssociate Professor, Department of Ophthalmology,

University of Rochester Medical School, Flaum Eye Institute, Rochester, New York

4 13

vision for LIFEtogether we can stop blindness from glaucoma.

Board of Directors

Board ChairAndrew G. Iwach, MDGlaucoma Center of San FranciscoSan Francisco, CA

President and CEO Thomas M. BrunnerGlaucoma Research FoundationSan Francisco, CA

Vice ChairRobert L. Stamper, MDUniversity of CaliforniaSan Francisco, CA

SecretaryRick Halprin, CPADirector, Professional Affairs (retired)Forth Worth, TX

TreasurerCharles R. Wilmoth Wells Fargo Advisors, LLC San Francisco, CA

DirectorsFrederick H. BrinkmannDirector, Information Technology (Retired)Santa Rosa, CA

Timothy J. DwyerPrivate InvestorWoodside, CA

Adrienne L. Graves, PhDIndependent DirectorSan Francisco, CA

Yehia Hashad, MD Allergan, Inc.Irvine, CA

Linda C. LinckDelta Gamma FoundationLafayette, CA

Dennis E. SingletonSpieker PartnersMenlo Park, CA

Monica L. Vetter, PhDUniversity of UtahSalt Lake City, UT

Martin B. Wax, MDPanOptica, Inc.Bernardsville, NJ

Ruth D. Williams, MDWheaton Eye ClinicWheaton, IL

Mona ZanderThe Mona and Ed Zander Family FoundationCarmel, CA

Founders John Hetherington, Jr., MDUniversity of CaliforniaSan Francisco, CA

H. Dunbar Hoskins, Jr., MDAmerican Academy of Ophthalmology (Retired)San Francisco, CA

Robert N. Shaffer, MD(1912–2007)

Honorary Advisory BoardF.T. BarrAfex International, Inc.Houston, TX

June Behrendt OttoThe Edward J. Daly FoundationSan Francisco, CA

Sarah BrownSan Francisco, CA

Steven KirschSan Jose, CA

Roger McGuinnWindemere, FL

Robert C. NevinsLafayette, CA

David E.I. Pyott Former Chairman and CEO of Allergan, Inc. Irvine, CA

Cary R. Rayment Alcon, Inc. (Retired) Cle Elum, WA

Professional StaffThomas M. BrunnerPresident and CEO

Nancy GraydonExecutive Director of Development

Andrew L. JacksonDirector of Communications

Catalina San AgustinDirector of Operations

Aileen TrieuAssociate Director of Development

Christie D’AngeloAssistant Director, Events and Volunteer Management

Michelle DavidsonEvent Program Manager

Briana FosterDevelopment Assistant

research VISION

Some of the most important discoveries in scientific research come from an investigator with a new, untested idea who needs funding to explore a creative project.

“The Shaffer program is perfect for young researchers with exciting ideas but little funding.”

Tonia Rex, PhDVanderbilt Eye Institute Director of Resident Research

and Co-Director of the Gene and Protein Analysis Module in the Vanderbilt Vision Research CenterVisit glaucoma.org/grants to learn more about our 2016 research grants..

We know that research is the answer—research built on the knowledge and discoveries of many scientists and laboratories. The 2016 research grants were made possible through leadership gifts from The Frank Stein and Paul S. May Grants for Innovative Glaucoma Research,

The Alcon Foundation, The Melza M. and Frank Theodore Barr Foundation, Inc., the Dr. Henry A. Sutro Family Grant for Research, and Dr. James and Elizabeth Wise. These one-year research grants were funded at $40,000 each to explore promising new ideas.

2016 RESEARCH GRANTSresearch holds the answers…and the cure.

3

Evan B. Stubbs, Jr., PhD Edward Hines, Jr.

VA Hospital, Hines, Illinois

Frank Talke, PhDUniversity of California, San Diego, California

David T. Stark, MD, PhDStein Eye Institute,

David Geffen School of Medicine at UCLA,

Los Angeles, California

Ian Pitha, MD, PhDJohns Hopkins University,

Wilmer Eye Institute, Baltimore, Maryland

Carla J. Siegfried, MDWashington University

School of Medicine, St. Louis, Missouri

W. Daniel Stamer, PhDDuke University Eye Center

Durham, North Carolina

Kevin Park, PhDUniversity of Miami Miller

School of Medicine, Miami, Florida

Louis R. Pasquale, MDCo-investigator

Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School,

Boston, Massachusetts

David A. Sullivan, MS, PhD, FARVO

“Support from GRF allowed me to use creative and alternative approaches to my research.”

Sayoko E. Moroi, MD, PhDProfessor, Ophthalmology and Visual Sciences,

Kellogg Eye Center, University of Michigan

“The grant from GRF was critically important for our new research strategy.”

Thomas A. Reh, PhDProfessor, Department of Biological Structure, University of Washington School of Medicine,

Seattle, Washington

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“No one should have to fear blindness from glaucoma.”

– Thomas M. Brunner, President and CEO

“We accelerate new and safe solutions for glaucoma patients.”

– Andrew G. Iwach, MD, Chair, Board of Directors

251 Post Street, Suite 600, San Francisco, CA 94108 – (415) 968-3162 – www.glaucoma.org

GRF CouncilA national leadership council of physicians working with GRF to improve access to informative and unbiased educational materials for all glaucoma patients.

Chair, GRF CouncilCarl Migliazzo, MD

(Central Regional Councilor)

GRF Councilors Stuart F. Ball, MDRobert J. Barnes, MDMichael S. Berlin, MDKathryn Bollinger, MDSteven V.L. Brown, MD, FACSDean Carlson, MD John S. Cohen, MD

(Midwest Regional Councilor)Randy Craven, MDRobert J. Derick, MDMonte Dirks, MDAmish Doshi, MDDoreen Fazio, MDRobert Feldman, MD

(Southwest Regional Councilor)Gloria P. Fleming, MDDavid Gilbert, MDLinda Greff, MDAgnes Huang, MDDan Jewelewicz, MDMartin B. Kaback, MDL. Jay Katz, MD

(Northeast Regional Councilor)Anup Khatana, MDDouglas Kohl, MDMichael S. Korey, MDRohit Krishna, MDRishi Kumar, MD

Linda Lawrence, MDRichard Lehrer, MDSteve Litinsky, MD

(Southeast Regional Councilor)Charles McMahon, MD

(Mountain Regional Councilor)Anne Miller, MDKevin Miller, MDJohann Ohly, MDDavid J. Palmer, MDCindy Penzler, MDJames Plotnik, MD, FACSAndrew Prince, MDAndrew Rabinowitz, MDGeorge Reiss, MDMichael Sakamoto, MD

(Western Regional Councilor)Keith Sanford, MDSonja W. Schluter, MD, MPHBradley Schuster, MD

(Mountain Regional Councilor)Arthur L. Schwartz, MDDonald Schwartz, MDGail F. Schwartz, MDMy Le Shaw, MDRajesh Shetty, MDCharles Eric Shrader, MDOluwatosin Smith, MD

(Southwest Regional Councilor)Michael Stiles, MDShigemi Sugiki, MDThomas Tayeri, MDSteven Vold, MD

(Southern Regional Councilor)Brian Welcome, MDMark Werner, MDRuth D. Williams, MD

(Midwest Regional Councilor)Jeffrey Zink, MD

VISIONfor life.

Dear Friends,

At Glaucoma Research Foundation, our bold vision is a future without glaucoma. With generous support from you and others dedicated to our mission we can make Vision for Life a reality for all those at risk and suffering from glaucoma. We are a catalyst for game-changing diagnostics, for innovative treatment options, and ultimately for a cure. This bold vision requires

intense focus, careful planning, thoughtful and creative research funding, and meaningful education and outreach. Thank you for your ongoing partnership. Together, we are closer than ever to achieving Vision for Life for all who have glaucoma and are at risk of glaucoma.

Andrew G. Iwach, MDChair, Board of Directors

Thomas M. BrunnerPresident and CEO

our FOCUSfinding a cure.

2016 ANNUAL REPORT

“If you’ve got glaucoma, GRF is the best community out there— they’re looking forward for the cure.”

– Catherine Wilmoth and her son, Christopher who was diagnosed with glaucoma

when he was 7 months old.