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1 First Quarter 2015 Results April 30, 2015

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Page 1: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

1

First Quarter 2015 Results April 30, 2015

Page 2: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

2 2 Safe Harbor Statement under the U.S. Private Securities Litigation Reform Act of 1995:

The following discussion and analysis contains forward-looking statements, which are based on management’s current beliefs and expectations and involve a number of known and unknown risks and uncertainties that could cause our future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. Important factors that could cause or contribute to such differences include risks relating to: our ability to develop and commercialize additional pharmaceutical products; competition for our specialty products, especially Copaxone® (including competition from orally-administered alternatives, as well as from generic equivalents such as the Sandoz product recently approved by the FDA) and our ability to migrate users to our 40 mg/mL version and maintain patients on that version; our ability to identify and successfully bid for suitable acquisition targets or licensing opportunities, or to consummate and integrate acquisitions; the possibility of material fines, penalties and other sanctions and other adverse consequences arising out of our ongoing FCPA investigations and related matters; our ability to achieve expected results from the research and development efforts invested in our pipeline of specialty and other products; our ability to reduce operating expenses to the extent and during the timeframe intended by our cost reduction program; the extent to which any manufacturing or quality control problems damage our reputation for quality production and require costly remediation; increased government scrutiny in both the U.S. and Europe of our patent settlement agreements; our exposure to currency fluctuations and restrictions as well as credit risks; the effectiveness of our patents, confidentiality agreements and other measures to protect the intellectual property rights of our specialty medicines; the effects of reforms in healthcare regulation and pharmaceutical pricing, reimbursement and coverage; governmental investigations into sales and marketing practices, particularly for our specialty pharmaceutical products; adverse effects of political or economic instability, major hostilities or acts of terrorism on our significant worldwide operations; interruptions in our supply chain or problems with internal or third-party information technology systems that adversely affect our complex manufacturing processes; significant disruptions of our information technology systems or breaches of our data security; competition for our generic products, both from other pharmaceutical companies and as a result of increased governmental pricing pressures; competition for our specialty pharmaceutical businesses from companies with greater resources and capabilities; the impact of continuing consolidation of our distributors and customers; decreased opportunities to obtain U.S. market exclusivity for significant new generic products; potential liability in the U.S., Europe and other markets for sales of generic products prior to a final resolution of outstanding patent litigation; our potential exposure to product liability claims that are not covered by insurance; any failure to recruit or retain key personnel, or to attract additional executive and managerial talent; any failures to comply with complex Medicare and Medicaid reporting and payment obligations; significant impairment charges relating to intangible assets, goodwill and property, plant and equipment; the effects of increased leverage and our resulting reliance on access to the capital markets; potentially significant increases in tax liabilities; the effect on our overall effective tax rate of the termination or expiration of governmental programs or tax benefits, or of a change in our business; variations in patent laws that may adversely affect our ability to manufacture our products in the most efficient manner; environmental risks; and other factors that are discussed in our Annual Report on Form 20-F for the year ended December 31, 2014 and in our other filings with the U.S. Securities and Exchange Commission (the "SEC"). Forward-looking statements speak only as of the date on which they are made and we assume no obligation to update or revise any forward-looking statements or other information contained in this report, whether as a result of new information, future events or otherwise. You are advised, however, to consult any additional disclosures we make in our reports to the SEC on Form 6-K. Also note that we provide a cautionary discussion of risks and uncertainties under “Risk Factors” in our Annual Report on Form 20-F for the year ended December 31, 2014. These are factors that we believe could cause our actual results to differ materially from expected results. Other factors besides those listed could also adversely affect us. This discussion is provided as permitted by the Private Securities Litigation Reform Act of 1995.

Page 3: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

3 3

Erez Vigodman President & CEO

Page 4: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

4 4

Q1 2015* Q1 2014* (1) Change Revenues $m 4,982 5,001 (0.4%)

Operating Income $m 1,533 1,381 11%

Net Income $m 1,165 1,051 11%

EPS $ 1.36 1.23 11%

Cash Flow from Operations $m 1,354 898 51%

Free Cash Flow $m 1,213 673 80%

*Net income, operating income and EPS are non GAAP results. (1) Adjusted for exclusion of equity compensation

Q1 2015 – Financial Highlights Strong Results on All Fronts

Page 5: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

5 5 Making Progress on Our Key Priorities for 2015

Continue solidifying the generics business, improve its profitability by additional 400bps and drive organic growth

Deliver on the promise in our specialty pipeline

Further maintain the Copaxone® franchise and continue to enhance our current product offerings

Generate $500m in net cost reductions

Continue enhancing the competitiveness of our operational network

Continue the transformation of the company to create its new future

Strong focus on business development

©

Page 6: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

6 6 Generics Highlights Continued Growth and Improvement in Generics

Significantly improved profit despite FX impact - 59% increase to $799 million

Revenues $2.6 billion, up 9%

Major improvement in profitability to 30.5%

US - Successful launch of generic Nexium® US - Solid performance of the base business

International Growth Markets - Double digit growth in local currency terms

EU - Strong performance in Germany, UK and Italy. Record profitability levels

OTC revenues up 20% in local currency terms; Profitability improved significantly

Page 7: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

7 7

45.2% 43.5% 41.3% 43.3% 46%

20.2% 19.9% 16.7%

21.9% 27%

10%

20%

30%

40%

50%

FY11 FY12 FY13 FY14 FY15 mid-point

Gross Profit Margin Segment Profit Margin

Profitability consists of gross profit, less S&M and R&D expenses related to the segment * Segment profitability does not include G&A expenses, amortization and certain other items

Continued Growth and Improvement in Generics

Continue to improve operating profitability

More focus on key markets and portfolio management

Execution of growth market strategy

Clear strategy for OTC

Sales force effectiveness in key markets

Page 8: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

8 8

Registration

CEP-33237 ER Hydrocodone (abuse det.) US - Pain Copaxone® 40mg 3w ROW Multiple sclerosis Copaxone® 20mg per Day Japan Multiple sclerosis Reslizumab IV Asthma Bendamustine Rapid Infusion* CLL, NHL

CNS & Pain Respiratory Other * Filed by Eagle Pharmaceutical, commercialized by Teva Note: Pipeline correct as of April 15, 2015. Phase 1 includes also projects designated for IND filing

Phase 1

TV-46763 (abuse deterrent) Pain TV-46139 (abuse deterrent) Pain Fluticasone Salmeterol Spiromax EU Asthma, COPD Reslizumab SC Asthma Fluticasone Salmeterol (MDI) EU Asthma, COPD TEV-46017 (tidal inhaler) COPD TEV-48108 (tidal inhaler) COPD TEV-90110 HIV TEV-90112 HIV

Phase 2

Laquinimod Multiple sclerosis (progressive forms) Laquinimod Huntington’s disease Pridopidine Huntington’s disease TV-45070 Topical Osteoarthritis pain TV-45070 Topical Neuropathic pain TEV-48125 (anti CGRP) Chronic and episodic migraine CEP-41750 (mesenchymal precursor cell) Acute myocardial infarction Albutropin Growth hormone deficiency

Phase 3

Laquinimod Multiple sclerosis (relapsing remitting) Fluticasone Propionate MDPI Asthma Fluticasone Salmeterol MDPI Asthma QVAR® (BAI) US Asthma CEP-41750 (mesenchymal precursor cell) Chronic heart failure

SD-809 Tourette syndrome SD-560 Idiopathic pulmonary fibrosis/other fibrotic conditions

SD-809 Tardive dyskinesia SD-809

HD (Mid-2015 NDA filing)

Auspex – pending deal completion

Teva Specialty pipeline - pending Auspex deal

Page 9: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

9 9 Delivering On The Promise In Our Pipeline

ProAir® RespiClick NDA approved - first and only breath-actuated dry-powder rescue inhaler for the treatment of acute asthma symptoms. Launch expected in Q2 15.

Reslizumab IV BLA submitted for the treatment of moderate to severe asthma.

TEV-48125 (CGRP MAb) positive phase 2b results in chronic and episodic migraine.

Q1 15 Update

Page 10: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

10 10

• TEV-48125 is the first anti-CGRP compound to report positive data in the disease

• The two tested doses were positive on primary and secondary endpoints (decrease in the number of hours and of headache days at three months relative to baseline)

• Both doses also separated from placebo at 1 month

• TEV-48125 significantly decreased consumption of triptans, different than Botox

• Data to be presented at the International Headache Society

Two active doses tested

Endpoints – Decrease in migraine (primary) and headache (secondary) days at three months relative to baseline

Both doses separated from placebo on primary and secondary endpoints (highly statistically significant after adjustments for multiplicity in two-sided tests)

Both doses also significantly separated at 1 month for both endpoints

No safety concerns in the episodic (or chronic) migraine trials

Data submitted to the American Headache Society conference

TEV-48125 Episodic Migraine Chronic Migraine

Page 11: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

11 11

• First anti-CGRP antagonist to show positive efficacy results in chronic and episodic migraine

• Four dosing paradigms tested across the two conditions. All positive for primary and secondary endpoints, and at 1 month of therapy

• Only monoclonal antibody anti CGRP that has separated from placebo across the entire duration of the study for primary and secondary

• No important safety concerns were identified

TEV-48125

Page 12: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

12 12

SD-809 Provides Substantial Addressable Market Opportunities with Significant Commercial Potential

Huntington’s Disease

Tardive Dyskinesia

Tourette Syndrome

Estimated Patient Population (U.S.)

% of Physicians who suggested they would prescribe SD-8091 Other Considerations

85%

94%

64%

Severe

Moderate

Mild

84%

84%

81%

Severe

Moderate

Mild

89%

90%

73%

Severe

Moderate

Mild

1 Source: Healogix physician survey.

~30,000 Patients

~350,000 Patients

~150,000 Patients

Only one approved drug in the US: Tetrabenazine – Only 5% of patients treated – 2014 sales of ~$300mm – Annual price per patient of $80-$85k – Established reimbursement landscape

Received FDA orphan designation Expected launch in 2016

No approved treatment in the US – Tetrabenazine is approved in the EU

Limited off-label usage of Tetrabenazine in the US despite significant clinical response – Improved profile should result in increased usage

Only one approved drug in the US: Aripiprazole – Associated with drowsiness, agitation, weight

gain, and sleep disturbances Limited off-label usage of Tetrabenazine despite

significant clinical response Received FDA orphan designation

Majority of movement disorder patients treated by neurologists – Highly synergistic with Teva’s premier neuroscience sales force

SD-809: Significant Near-Term Commercial Opportunity

Page 13: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

13 13

Frequency of Adverse Events: SD-809 Placebo (%)

Depression 4 % 7 %

Somnolence 11 % 4 %

Akathisia / Restlessness 2 % 2 %

Anxiety 2 % 2 %

Irritability 7 % 13 %

Fatigue 7 % 4 %

Insomnia 7 % 4 %

Parkinsonism / Bradykinesia 0 % 0 %

QT Prolongation: < 5 milliseconds

Dosing Frequency: BID (2 x day)

SD-809: Favorable Side Effect Profile; BID Dosing

Page 14: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

14 14

Eyal Desheh EVP, Chief Financial Officer

Page 15: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

15

Q1 2015 Results

Page 16: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

16 16

Q1 2015* Q1 2014* (1) Change

Revenues $m 4,982 5,001 (0.4%)

Operating Income $m 1,533 1,381 11%

Net Income $m 1,165 1,051 11%

EPS $ 1.36 1.23 11%

Cash flow from Operations $m 1,354 898 51%

*Net income, operating income and EPS are non GAAP results. (1) Adjusted for exclusion of equity compensation

Q1 2015

Page 17: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

17 17 Foreign Exchange Impact

Q1 2015 Q1 2014 Change ($m) Fx Effect* ( $m) Real Change

Revenues $m 4,982 5,001 (19) (368) 349

Operating income $m 1,533 1,381 152 (42) 194

*Includes profits from certain hedging transactions

Page 18: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

18 18 Cash Flow Trends

673 882

1,218 1,483

1,213 225

171

206

269

141

Q1 2014 Q2 2014 Q3 2014 Q4 2014 Q1 2015

$ million

Free Cash Flow*

Asset Purchase, Net

Cash From Operations 898 1,053

1,424

* Commencing Q4 2014, the data presented has been conformed to reflect the revised definition of free cash flow before dividend, for all periods.

1,752

1,354 +51%

+80%

Page 19: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

19 19 Quarterly Revenue Breakdown by Segment

2,398 - 48% 2,621 – 52%

1,070 - 21% 924 – 19%

1,044 - 21% 1,032 – 21%

489 - 10% 405 - 8%

Q1 14 Q1 15

OTC & Other

Specialty ex-MS

MS

Generics

$ million

5,001 4,982

Page 20: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

20 20

30% 44%

46% 36%

21% 17% 3% 3%

Q1 14 Q1 15

OTC & Others

Specialty ex-MS

MS

Generics

Quarterly Profit* Breakdown by Segment

* Segment profit consists of gross profit, less S&M and R&D expenses related to the segment. Segment profit does not include G&A expenses, amortization and certain other items.

1,826 1,674

$ million

Page 21: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

21 21 Generics Segment Gross Profit and Profitability* Evolution

* Segment profit consists of gross profit, less S&M and R&D expenses related to the segment. Segment profit does not include G&A expenses, amortization and certain other items. Segment profitability is segment profit as a percentage of segment revenues.

21.0% 21.3% 23.0% 23.0%

30.5%

43.5% 41.7%

44.3% 43.9%

49.0%

Q1 14 Q2 14 Q3 14 Q4 14 Q1 15

Profit Margin* Gross Profit Margin

Page 22: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

22 22

2,629 - 53% 2,921 - 59%

1,507 - 30% 1,267 - 25%

865 - 17% 794 - 16%

Q1 14 Q1 15

ROWEuropeUS

5,001 4,982

$ million Quarterly Revenue Breakdown by Market

Page 23: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

23 23 Quarterly Revenues

5,001 4,982

431

43 32

368

48 109

Q1 2014 Generics Specialtyex-MS

OTC & Other FX US OTC* MS Q1 2015

All data, except Fx, are net of the impact of foreign exchange fluctuations. *In July 2014, we sold our U.S. OTC plants, previously purchased from P&G, back to P&G.

$ million

Page 24: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

24 24 Copaxone® Revenues Evolution

$ million

816 835 732

254 286

192

25%

27%

29%

31%

33%

35%

0

200

400

600

800

1,000

1,200

Q1 14 Q4 14 Q1 15

US sales Ex-US sales US TRx MS*

* Market share data, including historic data, is based on IMS March 2015 data.

Revenues fluctuate but demand in the US is stable

Page 25: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

25 25 Quarterly Operating Income bridging

1,381 1,381 1,603 1,575 1,533 1,533

312

90

28 42

Q1 2014 Generics* MS Specialtyex-MS

Fx Q1 2015

* Segment profit consists of gross profit, less S&M and R&D expenses related to the segment. Segment profit does not include G&A expenses, amortization and certain other items. -Generics includes profit of other activities

$ million

Page 26: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

26 26 Liquidity Trends

Leverage

Debt/EBITDA

33% 31% 31% 32% 34% 35% 1.73 1.67 1.76 1.90 2.04 2.16

22.6 23.0 23.6 23.7 23.4 22.7

12.2 11.8 11.2 10.6 10.3 11.0

Q4 2013 Q1 2014 Q2 2014 Q3 2014 Q4 2014 Q1 2015

Debt

Equity

Gross debt increased by $0.7B from Dec 31, 2014

$ billion

Page 27: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

27 27 Teva’s Dividend Payments

Total dividends represent payment of the dividend declared for the quarter. Current quarter data is an estimate.

164 167 172 203 203 204 190 174

230 237 214

281 268 264 276 291 299 294 272

290 288

$0.00

$0.05

$0.10

$0.15

$0.20

$0.25

$0.30

$0.35

$0.40

0

50

100

150

200

250

300

350

Total Dividend ($m) $ per Share

Q1 2015 dividend per share of $0.34

Page 28: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

28 28 2015 Business Outlook: Increased Despite Currency Volatility and Approval of Copaxone® Generic

2015E Net Revenues ($b) 19.0-19.4

Gross Profit (%) 59.5%-61.5%

R&D ($b) 1.3-1.4

S&M ($b) 3.3-3.5

G&A ($b) 1.1-1.2

Operating Income* ($b) 5.7-5.9

Finance Expenses ($m) 250-290

Tax (%) 19%-21%

Number of Shares (M) 850-860

EPS ($) 5.05-5.35

Cash Flow from Operations ($b) 4.3-4.7

Page 29: First Quarter 2015 Results · – 2014 sales of ~$ 300mm – Annual price per patient of $80-$85k – Established reimbursement landscape Received FDA orphan designation Expected

Thank You